Project
avrg: GFI1 WT vs 36n/n vs KD
Navigation
Downloads
Results for Klf6_Patz1
Z-value: 3.20
Motif logo
Transcription factors associated with Klf6_Patz1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Klf6 | mm39_v1_chr13_+_5911481_5911521 | 0.91 | 3.3e-02 | Click! |
| Patz1 | mm39_v1_chr11_+_3239165_3239281 | 0.77 | 1.2e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr7_+_43959637 Show fit | 3.24 |
ENSMUST00000107938.8
|
SH3 and multiple ankyrin repeat domains 1 |
|
| chr6_-_119825054 Show fit | 2.13 |
ENSMUST00000079582.5
|
ELKS/RAB6-interacting/CAST family member 1 |
|
| chrX_-_71318353 Show fit | 2.03 |
ENSMUST00000064780.4
|
gamma-aminobutyric acid (GABA) A receptor, subunit epsilon |
|
| chr3_+_96604390 Show fit | 2.02 |
ENSMUST00000162778.3
ENSMUST00000064900.16 |
protein inhibitor of activated STAT 3 |
|
| chr14_-_52516695 Show fit | 1.99 |
ENSMUST00000167116.8
ENSMUST00000100631.11 |
RAB2B, member RAS oncogene family |
|
| chr7_-_15781838 Show fit | 1.99 |
ENSMUST00000210781.2
|
BRD4 interacting chromatin remodeling complex associated protein |
|
| chr17_-_32503107 Show fit | 1.83 |
ENSMUST00000237692.2
|
bromodomain containing 4 |
|
| chr6_-_38852857 Show fit | 1.83 |
ENSMUST00000162359.8
|
homeodomain interacting protein kinase 2 |
|
| chr19_+_10502679 Show fit | 1.82 |
ENSMUST00000235674.2
|
cleavage and polyadenylation specific factor 7 |
|
| chr2_-_143853122 Show fit | 1.81 |
ENSMUST00000016072.12
ENSMUST00000037875.6 |
ribosome binding protein 1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Klf6_Patz1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 5.0 | GO:0000083 | regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083) |
| 0.4 | 4.3 | GO:0050882 | voluntary musculoskeletal movement(GO:0050882) |
| 0.1 | 3.8 | GO:0060612 | adipose tissue development(GO:0060612) |
| 0.0 | 3.6 | GO:0035023 | regulation of Rho protein signal transduction(GO:0035023) |
| 0.2 | 3.5 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.0 | 3.3 | GO:0043149 | contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149) |
| 0.5 | 2.9 | GO:0032483 | regulation of Rab protein signal transduction(GO:0032483) |
| 0.3 | 2.8 | GO:0046959 | habituation(GO:0046959) |
| 0.3 | 2.7 | GO:0032485 | regulation of Ral protein signal transduction(GO:0032485) |
| 0.9 | 2.6 | GO:0060010 | Sertoli cell fate commitment(GO:0060010) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 9.5 | GO:0016605 | PML body(GO:0016605) |
| 0.0 | 5.2 | GO:0015629 | actin cytoskeleton(GO:0015629) |
| 0.1 | 3.9 | GO:0002102 | podosome(GO:0002102) |
| 0.3 | 3.8 | GO:0008024 | cyclin/CDK positive transcription elongation factor complex(GO:0008024) |
| 0.1 | 3.5 | GO:0005849 | mRNA cleavage factor complex(GO:0005849) |
| 0.1 | 3.4 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
| 0.0 | 3.2 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
| 0.0 | 2.4 | GO:0036126 | sperm flagellum(GO:0036126) |
| 0.1 | 2.2 | GO:0071565 | nBAF complex(GO:0071565) |
| 0.4 | 2.1 | GO:0000802 | transverse filament(GO:0000802) nuclear meiotic cohesin complex(GO:0034991) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 13.9 | GO:0001071 | nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700) |
| 0.0 | 10.3 | GO:0001228 | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228) |
| 0.0 | 6.6 | GO:0005096 | GTPase activator activity(GO:0005096) |
| 0.0 | 6.4 | GO:0017124 | SH3 domain binding(GO:0017124) |
| 0.1 | 5.8 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.4 | 5.1 | GO:0046790 | virion binding(GO:0046790) |
| 0.0 | 4.3 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.1 | 4.2 | GO:0001103 | RNA polymerase II repressing transcription factor binding(GO:0001103) |
| 0.1 | 4.1 | GO:0030506 | ankyrin binding(GO:0030506) |
| 0.0 | 4.1 | GO:0008013 | beta-catenin binding(GO:0008013) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 6.0 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
| 0.1 | 4.6 | PID ECADHERIN STABILIZATION PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.1 | 3.9 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.2 | 3.1 | ST JAK STAT PATHWAY | Jak-STAT Pathway |
| 0.1 | 3.0 | PID CD40 PATHWAY | CD40/CD40L signaling |
| 0.0 | 3.0 | PID P53 REGULATION PATHWAY | p53 pathway |
| 0.1 | 2.8 | PID WNT NONCANONICAL PATHWAY | Noncanonical Wnt signaling pathway |
| 0.0 | 2.6 | PID ERBB1 INTERNALIZATION PATHWAY | Internalization of ErbB1 |
| 0.1 | 2.3 | ST WNT CA2 CYCLIC GMP PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
| 0.0 | 2.3 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.9 | REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
| 0.0 | 4.3 | REACTOME NRAGE SIGNALS DEATH THROUGH JNK | Genes involved in NRAGE signals death through JNK |
| 0.1 | 3.6 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.1 | 3.2 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.1 | 3.1 | REACTOME PROCESSING OF INTRONLESS PRE MRNAS | Genes involved in Processing of Intronless Pre-mRNAs |
| 0.1 | 2.8 | REACTOME SEMA4D IN SEMAPHORIN SIGNALING | Genes involved in Sema4D in semaphorin signaling |
| 0.1 | 2.6 | REACTOME EGFR DOWNREGULATION | Genes involved in EGFR downregulation |
| 0.1 | 2.5 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
| 0.0 | 2.3 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.1 | 2.1 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |