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avrg: GFI1 WT vs 36n/n vs KD

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Results for Klf8

Z-value: 1.07

Motif logo

Transcription factors associated with Klf8

Gene Symbol Gene ID Gene Info
ENSMUSG00000041649.14 Kruppel-like factor 8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Klf8mm39_v1_chrX_+_152020744_1520208380.838.4e-02Click!

Activity profile of Klf8 motif

Sorted Z-values of Klf8 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr13_+_120151982 0.61 ENSMUST00000179869.3
ENSMUST00000224188.2
3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1
chr2_-_164197987 0.60 ENSMUST00000165980.2
secretory leukocyte peptidase inhibitor
chr17_-_34219225 0.57 ENSMUST00000238098.2
ENSMUST00000087189.7
ENSMUST00000173075.3
ENSMUST00000172912.8
ENSMUST00000236740.2
ENSMUST00000025181.18
histocompatibility 2, K1, K region
chr19_+_6952580 0.53 ENSMUST00000237084.2
ENSMUST00000236218.2
ENSMUST00000237235.2
protein phosphatase 1, regulatory inhibitor subunit 14B
chr7_-_103477126 0.52 ENSMUST00000023934.8
hemoglobin, beta adult s chain
chr10_+_79716876 0.51 ENSMUST00000166201.2
proteinase 3
chr16_+_30418535 0.49 ENSMUST00000059078.4
family with sequence similarity 43, member A
chr19_-_6117815 0.48 ENSMUST00000162575.8
ENSMUST00000159084.8
ENSMUST00000161718.8
ENSMUST00000162810.8
ENSMUST00000025713.12
ENSMUST00000113543.9
ENSMUST00000160417.8
ENSMUST00000161528.2
transmembrane 7 superfamily member 2
chr16_+_17884267 0.46 ENSMUST00000151266.8
ENSMUST00000066027.14
ENSMUST00000155387.8
DiGeorge syndrome critical region gene 6
chr18_-_43610829 0.44 ENSMUST00000057110.11
eukaryotic translation initiation factor 3, subunit J2
chr15_-_79976016 0.44 ENSMUST00000185306.3
ribosomal protein L3
chr14_-_55828511 0.44 ENSMUST00000161807.8
ENSMUST00000111378.10
ENSMUST00000159687.2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr19_+_6952319 0.44 ENSMUST00000070850.8
protein phosphatase 1, regulatory inhibitor subunit 14B
chr8_+_73449907 0.43 ENSMUST00000109950.5
ENSMUST00000004494.16
ENSMUST00000212095.2
ENSMUST00000212096.2
transcriptional regulator, SIN3B (yeast)
chr13_+_73476629 0.41 ENSMUST00000221730.2
mitochondrial ribosomal protein L36
chr7_-_126625657 0.39 ENSMUST00000205568.2
MYC-associated zinc finger protein (purine-binding transcription factor)
chr17_-_26014613 0.39 ENSMUST00000235889.2
predicted gene, 50367
chr10_+_39245746 0.39 ENSMUST00000063091.13
ENSMUST00000099967.10
ENSMUST00000126486.8
Fyn proto-oncogene
chr17_+_35117905 0.38 ENSMUST00000097342.10
ENSMUST00000013931.12
euchromatic histone lysine N-methyltransferase 2
chr11_+_101215889 0.38 ENSMUST00000041095.14
ENSMUST00000107264.2
amine oxidase, copper containing 2 (retina-specific)
chr11_+_83637766 0.37 ENSMUST00000070832.3
WAP four-disulfide core domain 21
chr3_-_121608859 0.37 ENSMUST00000029770.8
ATP-binding cassette, sub-family D (ALD), member 3
chr2_+_174169351 0.37 ENSMUST00000124935.8
GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus
chr2_-_164198427 0.36 ENSMUST00000109367.10
secretory leukocyte peptidase inhibitor
chr14_+_122771734 0.36 ENSMUST00000154206.8
ENSMUST00000038374.13
ENSMUST00000135578.8
propionyl-Coenzyme A carboxylase, alpha polypeptide
chrX_-_74460168 0.34 ENSMUST00000033543.14
ENSMUST00000149863.3
ENSMUST00000114081.2
C-x(9)-C motif containing 4
mature T cell proliferation 1
chr17_+_46957151 0.33 ENSMUST00000002844.14
ENSMUST00000113429.8
ENSMUST00000113430.2
mitochondrial ribosomal protein L2
chr17_+_35117438 0.33 ENSMUST00000114033.9
ENSMUST00000078061.13
euchromatic histone lysine N-methyltransferase 2
chr11_-_120538928 0.32 ENSMUST00000239158.2
ENSMUST00000026134.3
myeloid-associated differentiation marker-like 2
chr1_-_188740023 0.32 ENSMUST00000085678.8
potassium channel tetramerisation domain containing 3
chr8_+_86026318 0.32 ENSMUST00000170141.3
ENSMUST00000034132.13
origin recognition complex, subunit 6
chr17_+_74645936 0.31 ENSMUST00000224711.2
ENSMUST00000024869.8
ENSMUST00000233611.2
spastin
chr19_+_36325683 0.31 ENSMUST00000225920.2
polycomb group ring finger 5
chr2_-_157408239 0.31 ENSMUST00000109528.9
ENSMUST00000088494.3
bladder cancer associated protein
chr15_-_89258012 0.31 ENSMUST00000167643.4
SCO2 cytochrome c oxidase assembly protein
chr19_-_6899173 0.30 ENSMUST00000025906.12
ENSMUST00000239322.2
estrogen related receptor, alpha
chr2_-_28730286 0.30 ENSMUST00000037117.6
ENSMUST00000171404.8
general transcription factor IIIC, polypeptide 4
chr3_-_121608809 0.29 ENSMUST00000197383.5
ATP-binding cassette, sub-family D (ALD), member 3
chr12_+_28725218 0.29 ENSMUST00000020957.13
acireductone dioxygenase 1
chr7_-_126625617 0.29 ENSMUST00000032916.6
MYC-associated zinc finger protein (purine-binding transcription factor)
chr5_+_122347792 0.29 ENSMUST00000072602.14
hydrogen voltage-gated channel 1
chr5_+_31078911 0.29 ENSMUST00000201571.4
ketohexokinase
chr1_-_106641940 0.29 ENSMUST00000112751.2
B cell leukemia/lymphoma 2
chr19_+_5540591 0.28 ENSMUST00000237122.2
cofilin 1, non-muscle
chrX_+_7750483 0.28 ENSMUST00000115663.10
ENSMUST00000096514.11
solute carrier family 35 (UDP-galactose transporter), member A2
chr5_+_115373895 0.28 ENSMUST00000081497.13
processing of precursor 5, ribonuclease P/MRP family (S. cerevisiae)
chr5_+_139777263 0.27 ENSMUST00000018287.10
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian)
chr9_-_114610879 0.27 ENSMUST00000084867.9
ENSMUST00000216760.2
ENSMUST00000035009.16
CKLF-like MARVEL transmembrane domain containing 7
chr5_+_32616566 0.27 ENSMUST00000202078.2
protein phosphatase 1 catalytic subunit beta
chr4_-_150998857 0.26 ENSMUST00000105675.8
Parkinson disease (autosomal recessive, early onset) 7
chr10_-_80426125 0.26 ENSMUST00000187646.2
ENSMUST00000191440.7
ENSMUST00000003436.12
abhydrolase domain containing 17A
chr10_-_90959817 0.26 ENSMUST00000164505.2
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3
chr11_+_115310885 0.25 ENSMUST00000103035.10
potassium channel tetramerisation domain containing 2
chr1_-_66902429 0.25 ENSMUST00000027153.6
acyl-Coenzyme A dehydrogenase, long-chain
chr8_-_85414220 0.25 ENSMUST00000238449.2
ENSMUST00000238687.2
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr11_-_101357046 0.25 ENSMUST00000040430.8
vesicle amine transport 1
chrX_-_72965434 0.25 ENSMUST00000096316.4
ENSMUST00000114390.8
ENSMUST00000114391.10
ENSMUST00000114387.8
N(alpha)-acetyltransferase 10, NatA catalytic subunit
chr17_+_25992761 0.24 ENSMUST00000237541.2
cytosolic iron-sulfur assembly component 3
chr5_+_124045552 0.24 ENSMUST00000166233.2
density-regulated protein
chr5_-_122639840 0.24 ENSMUST00000177974.8
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr9_-_96513529 0.24 ENSMUST00000034984.8
RAS p21 protein activator 2
chr19_-_6899121 0.24 ENSMUST00000173635.2
estrogen related receptor, alpha
chr8_+_86567600 0.24 ENSMUST00000053771.14
ENSMUST00000161850.8
phosphorylase kinase beta
chr17_-_26087696 0.23 ENSMUST00000236479.2
ENSMUST00000235806.2
ENSMUST00000026828.7
MAPK regulated corepressor interacting protein 2
chr19_-_12478803 0.23 ENSMUST00000045521.9
deltex 4, E3 ubiquitin ligase
chr11_+_70548022 0.23 ENSMUST00000157027.8
ENSMUST00000072841.12
ENSMUST00000108548.8
ENSMUST00000126241.8
enolase 3, beta muscle
chr12_+_72807985 0.22 ENSMUST00000021514.10
protein phosphatase 1A, magnesium dependent, alpha isoform
chr5_-_33812830 0.22 ENSMUST00000200849.2
transmembrane protein 129
chr5_-_143255713 0.22 ENSMUST00000161448.8
zinc finger protein 316
chr2_-_38534099 0.21 ENSMUST00000028083.6
proteasome (prosome, macropain) subunit, beta type 7
chrX_-_74460137 0.21 ENSMUST00000033542.11
mature T cell proliferation 1
chr8_-_86026385 0.21 ENSMUST00000034131.10
VPS35 retromer complex component
chr19_+_45991907 0.21 ENSMUST00000099393.4
HPS6, biogenesis of lysosomal organelles complex 2 subunit 3
chr5_+_31079177 0.21 ENSMUST00000031053.15
ENSMUST00000202752.2
ketohexokinase
chr11_+_115310963 0.20 ENSMUST00000106533.8
ENSMUST00000123345.2
potassium channel tetramerisation domain containing 2
chr15_-_97665524 0.20 ENSMUST00000128775.9
ENSMUST00000134885.3
Rap guanine nucleotide exchange factor (GEF) 3
chr2_+_121859025 0.20 ENSMUST00000028668.8
eukaryotic translation initiation factor 3, subunit J1
chrX_+_161543384 0.19 ENSMUST00000033720.12
ENSMUST00000112327.8
retinoblastoma binding protein 7, chromatin remodeling factor
chr11_+_60428788 0.18 ENSMUST00000044250.4
alkB homolog 5, RNA demethylase
chr1_+_135945798 0.18 ENSMUST00000117950.2
transmembrane protein 9
chr15_-_89258034 0.18 ENSMUST00000228977.2
SCO2 cytochrome c oxidase assembly protein
chr1_+_172327812 0.18 ENSMUST00000192460.2
transgelin 2
chrX_-_84820209 0.18 ENSMUST00000142152.2
ENSMUST00000156390.8
glycerol kinase
chr8_+_22682816 0.18 ENSMUST00000033866.9
vacuolar protein sorting 36
chrX_+_161543423 0.17 ENSMUST00000112326.8
retinoblastoma binding protein 7, chromatin remodeling factor
chr18_-_10610048 0.17 ENSMUST00000115864.8
ENSMUST00000145320.2
ENSMUST00000097670.10
establishment of sister chromatid cohesion N-acetyltransferase 1
chr4_+_148125630 0.17 ENSMUST00000069604.15
methylenetetrahydrofolate reductase
chrX_-_72965524 0.17 ENSMUST00000114389.10
N(alpha)-acetyltransferase 10, NatA catalytic subunit
chr11_+_119833589 0.17 ENSMUST00000106231.8
ENSMUST00000075180.12
ENSMUST00000103021.10
ENSMUST00000026436.10
ENSMUST00000106233.2
brain-specific angiogenesis inhibitor 1-associated protein 2
chr7_-_142522995 0.17 ENSMUST00000009392.6
achaete-scute family bHLH transcription factor 2
chr2_-_90735171 0.17 ENSMUST00000005647.4
NADH:ubiquinone oxidoreductase core subunit S3
chr9_-_21202353 0.17 ENSMUST00000086374.8
cyclin dependent kinase inhibitor 2D
chr8_+_13389656 0.16 ENSMUST00000210165.2
ENSMUST00000170909.2
transcription factor Dp 1
chr14_-_68170873 0.16 ENSMUST00000039135.6
dedicator of cytokinesis 5
chr5_-_88823472 0.16 ENSMUST00000113234.8
ENSMUST00000153565.8
G-rich RNA sequence binding factor 1
chr18_+_36414122 0.16 ENSMUST00000051301.6
purine rich element binding protein A
chr7_+_110628158 0.16 ENSMUST00000005749.6
CTR9 homolog, Paf1/RNA polymerase II complex component
chr1_-_20890437 0.16 ENSMUST00000053266.11
minichromosome maintenance complex component 3
chrX_-_72965536 0.16 ENSMUST00000033763.15
N(alpha)-acetyltransferase 10, NatA catalytic subunit
chr9_-_99450948 0.15 ENSMUST00000035043.12
armadillo repeat containing 8
chr14_-_20844074 0.15 ENSMUST00000080440.14
ENSMUST00000100837.11
ENSMUST00000071816.7
calcium/calmodulin-dependent protein kinase II gamma
chr2_+_167922924 0.15 ENSMUST00000052125.7
par-6 family cell polarity regulator beta
chr4_+_155896946 0.15 ENSMUST00000030944.11
cyclin L2
chr2_+_90735077 0.15 ENSMUST00000111464.8
ENSMUST00000090682.4
kelch repeat and BTB (POZ) domain containing 4
chr11_-_45835737 0.15 ENSMUST00000129820.8
U7 snRNP-specific Sm-like protein LSM11
chr3_+_96543143 0.15 ENSMUST00000165842.3
peroxisomal biogenesis factor 11 beta
chr4_-_132649798 0.14 ENSMUST00000097856.10
ENSMUST00000030696.11
family with sequence similarity 76, member A
chr13_-_43324824 0.14 ENSMUST00000220787.2
TBC1 domain family, member 7
chr9_-_45847344 0.14 ENSMUST00000034590.4
transgelin
chr5_-_123270449 0.14 ENSMUST00000186469.7
ras homolog family member F (in filopodia)
chr5_+_122348140 0.14 ENSMUST00000196187.5
ENSMUST00000100747.3
hydrogen voltage-gated channel 1
chr4_-_149747644 0.14 ENSMUST00000105689.8
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
chr7_+_101070897 0.14 ENSMUST00000163751.10
ENSMUST00000211368.2
ENSMUST00000166652.2
phosphodiesterase 2A, cGMP-stimulated
chr15_+_5173342 0.14 ENSMUST00000051186.9
ENSMUST00000228218.2
protein kinase, AMP-activated, alpha 1 catalytic subunit
chr5_-_123270702 0.14 ENSMUST00000031401.6
ras homolog family member F (in filopodia)
chr4_+_115641996 0.13 ENSMUST00000177280.8
ENSMUST00000176047.8
ATP synthase mitochondrial F1 complex assembly factor 1
chr9_-_21202693 0.13 ENSMUST00000213407.2
cyclin dependent kinase inhibitor 2D
chr1_+_135945705 0.13 ENSMUST00000063719.15
transmembrane protein 9
chr17_-_71158184 0.13 ENSMUST00000059775.15
TGFB-induced factor homeobox 1
chr11_-_120489172 0.13 ENSMUST00000026125.3
Aly/REF export factor
chr17_+_29487881 0.13 ENSMUST00000234845.2
ENSMUST00000235038.2
ENSMUST00000235050.2
ENSMUST00000120346.9
ENSMUST00000234377.2
ENSMUST00000235074.2
ENSMUST00000235040.2
ENSMUST00000234256.2
ENSMUST00000234459.2
cDNA sequence BC004004
chr11_+_86574811 0.13 ENSMUST00000108022.8
ENSMUST00000108021.2
peptidyl-tRNA hydrolase 2
chr8_-_86567506 0.13 ENSMUST00000034140.9
integrin alpha FG-GAP repeat containing 1
chr7_+_30264835 0.13 ENSMUST00000043850.14
IGF-like family receptor 1
chr19_+_42078859 0.12 ENSMUST00000235932.2
ENSMUST00000066778.6
phosphatidylinositol 4-kinase type 2 alpha
chr10_+_80003612 0.12 ENSMUST00000105365.9
cold inducible RNA binding protein
chr17_-_3608056 0.12 ENSMUST00000041003.8
transcription factor B1, mitochondrial
chr12_-_69274936 0.12 ENSMUST00000221411.2
ENSMUST00000021359.7
polymerase (DNA directed), epsilon 2 (p59 subunit)
chr5_+_129924564 0.12 ENSMUST00000041466.14
zinc finger, BED type containing 5
chrX_-_84820250 0.12 ENSMUST00000113978.9
glycerol kinase
chr7_+_28937859 0.11 ENSMUST00000108237.2
Yip1 interacting factor homolog B (S. cerevisiae)
chrX_+_20524565 0.11 ENSMUST00000089217.11
ubiquitin-like modifier activating enzyme 1
chr9_+_64868127 0.11 ENSMUST00000170517.9
ENSMUST00000037504.7
integrator complex subunit 14
chr17_-_25179635 0.11 ENSMUST00000024981.9
Jupiter microtubule associated homolog 2
chr10_-_90959853 0.11 ENSMUST00000170810.8
ENSMUST00000076694.13
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3
chr17_-_71158052 0.11 ENSMUST00000186358.6
TGFB-induced factor homeobox 1
chr9_+_108765701 0.11 ENSMUST00000026743.14
ENSMUST00000194047.3
ubiquinol-cytochrome c reductase core protein 1
chr11_+_120489358 0.10 ENSMUST00000093140.5
anaphase promoting complex subunit 11
chr17_+_47983587 0.10 ENSMUST00000152724.2
ubiquitin specific peptidase 49
chr2_+_122479770 0.10 ENSMUST00000047498.15
ENSMUST00000110512.4
expressed sequence AA467197
chrX_-_7834057 0.10 ENSMUST00000033502.14
GATA binding protein 1
chr15_+_78290975 0.10 ENSMUST00000043865.8
ENSMUST00000231159.2
ENSMUST00000169133.8
mercaptopyruvate sulfurtransferase
chr4_+_118745806 0.10 ENSMUST00000106361.3
ENSMUST00000105035.3
olfactory receptor 1330
chr12_-_79219382 0.10 ENSMUST00000055262.13
vesicle transport through interaction with t-SNAREs 1B
chr7_-_19133783 0.09 ENSMUST00000047170.10
ENSMUST00000108459.9
kinesin light chain 3
chr18_+_21134928 0.09 ENSMUST00000234536.2
ENSMUST00000052396.7
ring finger protein 138
chr7_-_92523396 0.09 ENSMUST00000209074.2
ENSMUST00000208356.2
ENSMUST00000032877.11
DNA damage-induced apoptosis suppressor
chr7_-_6334239 0.09 ENSMUST00000127658.2
ENSMUST00000062765.14
zinc finger protein 583
chr4_-_130068902 0.09 ENSMUST00000105998.8
tubulointerstitial nephritis antigen-like 1
chr17_-_71158703 0.08 ENSMUST00000166395.9
TGFB-induced factor homeobox 1
chr9_+_119766672 0.08 ENSMUST00000035100.6
tetratricopeptide repeat domain 21A
chr10_-_5755412 0.08 ENSMUST00000019907.8
F-box protein 5
chr7_+_28937746 0.08 ENSMUST00000108238.8
ENSMUST00000032809.10
Yip1 interacting factor homolog B (S. cerevisiae)
chr6_-_28397997 0.08 ENSMUST00000035930.11
zinc finger protein 800
chrX_-_50294652 0.08 ENSMUST00000114875.8
muscleblind like splicing factor 3
chr7_+_28937898 0.08 ENSMUST00000138128.3
ENSMUST00000142519.3
Yip1 interacting factor homolog B (S. cerevisiae)
chr11_+_11634967 0.08 ENSMUST00000141436.8
ENSMUST00000126058.8
IKAROS family zinc finger 1
chr5_+_32616187 0.08 ENSMUST00000015100.15
protein phosphatase 1 catalytic subunit beta
chr8_+_85763534 0.08 ENSMUST00000093360.12
transportin 2 (importin 3, karyopherin beta 2b)
chr11_-_76386190 0.07 ENSMUST00000108408.9
active BCR-related gene
chr5_+_88712840 0.07 ENSMUST00000196894.5
ENSMUST00000198965.5
RUN and FYVE domain containing 3
chr19_-_12742811 0.07 ENSMUST00000112933.2
ciliary neurotrophic factor
chr15_-_97665679 0.07 ENSMUST00000129223.9
ENSMUST00000126854.9
ENSMUST00000135080.2
Rap guanine nucleotide exchange factor (GEF) 3
chr9_-_106035308 0.07 ENSMUST00000159809.2
ENSMUST00000162562.2
ENSMUST00000036382.13
glycerate kinase
chr5_-_108808649 0.07 ENSMUST00000053913.13
diacylglycerol kinase, theta
chr8_+_85763780 0.07 ENSMUST00000211601.2
ENSMUST00000166592.2
transportin 2 (importin 3, karyopherin beta 2b)
chr12_+_18564466 0.07 ENSMUST00000177778.9
ENSMUST00000063216.6
RIKEN cDNA 5730507C01 gene
chr2_-_136958544 0.06 ENSMUST00000028735.8
jagged 1
chr11_-_76462353 0.06 ENSMUST00000072740.13
active BCR-related gene
chr16_-_94171533 0.06 ENSMUST00000113910.8
phosphatidylinositol glycan anchor biosynthesis, class P
chr8_+_105991280 0.06 ENSMUST00000036221.12
F-box and leucine-rich repeat protein 8
chr8_-_71112295 0.06 ENSMUST00000211715.2
ENSMUST00000210307.2
ENSMUST00000209768.2
ENSMUST00000070173.9
pyroglutamyl-peptidase I
chr7_+_51528788 0.06 ENSMUST00000107591.9
growth arrest specific 2
chr12_-_118265103 0.06 ENSMUST00000222314.2
ENSMUST00000026367.11
trans-acting transcription factor 4
chr11_+_70548513 0.06 ENSMUST00000134087.8
enolase 3, beta muscle
chr15_-_83033559 0.06 ENSMUST00000058793.14
polymerase (DNA-directed), delta interacting protein 3
chr19_-_53026965 0.05 ENSMUST00000183274.8
ENSMUST00000182097.2
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
chr17_-_46956920 0.05 ENSMUST00000233974.2
kinesin light chain 4
chr11_-_62539284 0.05 ENSMUST00000057194.9
leucine rich repeat containing 75A
chr2_+_28403084 0.05 ENSMUST00000135803.8
ral guanine nucleotide dissociation stimulator
chr2_+_32496957 0.05 ENSMUST00000113290.8
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chrX_+_74460275 0.05 ENSMUST00000118428.8
ENSMUST00000114074.8
ENSMUST00000133781.8
BRCA1/BRCA2-containing complex, subunit 3
chr15_+_78290896 0.05 ENSMUST00000167140.8
mercaptopyruvate sulfurtransferase
chr9_+_37466989 0.05 ENSMUST00000213126.2
sialic acid acetylesterase
chr1_-_51517548 0.05 ENSMUST00000027279.12
ENSMUST00000186684.7
ENSMUST00000188204.7
ENSMUST00000185534.2
ENSMUST00000188051.7
nucleic acid binding protein 1
chr16_-_18630365 0.04 ENSMUST00000096990.10
cell division cycle 45
chr2_+_174169492 0.04 ENSMUST00000156623.8
ENSMUST00000149016.9
GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus
chr10_+_4660119 0.04 ENSMUST00000105588.8
ENSMUST00000105589.2
estrogen receptor 1 (alpha)
chr9_-_34967081 0.04 ENSMUST00000215463.2
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chr1_-_157072060 0.04 ENSMUST00000129880.8
RAS protein activator like 2
chr2_-_91540864 0.04 ENSMUST00000028678.9
ENSMUST00000076803.12
autophagy related 13
chr8_+_95781722 0.04 ENSMUST00000058479.7
dynein regulatory complex subunit 7
chr7_+_16576821 0.03 ENSMUST00000168093.9
protein kinase D2
chr9_-_21202545 0.03 ENSMUST00000215619.2
cyclin dependent kinase inhibitor 2D
chrX_-_59449137 0.03 ENSMUST00000033480.13
ENSMUST00000101527.3
ATPase, class VI, type 11C
chr2_-_169973076 0.03 ENSMUST00000063710.13
zinc finger protein 217
chr9_+_114807546 0.03 ENSMUST00000183104.8
oxysterol binding protein-like 10
chr14_-_47025724 0.03 ENSMUST00000146629.3
ENSMUST00000015903.12
cornichon family AMPA receptor auxiliary protein 1
chr7_-_132616977 0.03 ENSMUST00000169570.8
C-terminal binding protein 2
chr14_+_54713557 0.03 ENSMUST00000164766.8
rad and gem related GTP binding protein 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Klf8

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 0.7 GO:0036166 phenotypic switching(GO:0036166) cellular response to cocaine(GO:0071314)
0.1 0.5 GO:0009744 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.1 0.6 GO:0002484 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway(GO:0002484) antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent(GO:0002485)
0.1 0.5 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.1 0.4 GO:0010286 heat acclimation(GO:0010286)
0.1 0.2 GO:1903233 regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233)
0.1 0.5 GO:1903179 regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181)
0.1 0.3 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.1 0.3 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.1 0.6 GO:0017198 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.1 0.3 GO:1904451 regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904451) positive regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904453)
0.1 0.3 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.1 0.3 GO:0042758 long-chain fatty acid catabolic process(GO:0042758)
0.1 0.3 GO:0051013 microtubule severing(GO:0051013)
0.1 0.7 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 0.3 GO:0032847 regulation of cellular pH reduction(GO:0032847)
0.1 0.2 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160)
0.0 0.1 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.0 0.2 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.2 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.0 0.1 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.0 0.2 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.3 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.0 0.2 GO:0070829 heterochromatin maintenance(GO:0070829)
0.0 0.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.2 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.1 GO:0030221 basophil differentiation(GO:0030221)
0.0 0.2 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.2 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.0 0.3 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.2 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.1 GO:0044375 regulation of peroxisome size(GO:0044375)
0.0 0.4 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 1.0 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 0.1 GO:0051439 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439)
0.0 0.1 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.0 0.3 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:0045660 positive regulation of neutrophil differentiation(GO:0045660)
0.0 0.1 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.2 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.3 GO:0048102 autophagic cell death(GO:0048102)
0.0 0.1 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.5 GO:0006878 cellular copper ion homeostasis(GO:0006878) respiratory chain complex IV assembly(GO:0008535)
0.0 0.1 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.1 GO:0048691 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
0.0 0.2 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.6 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.0 0.1 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.0 0.1 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.0 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) DNA replication preinitiation complex assembly(GO:0071163) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 0.5 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.4 GO:0050872 white fat cell differentiation(GO:0050872)
0.0 0.1 GO:0009092 homoserine metabolic process(GO:0009092) transsulfuration(GO:0019346) hydrogen sulfide biosynthetic process(GO:0070814)
0.0 0.1 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
0.0 0.3 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.1 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.1 GO:0070417 cellular response to cold(GO:0070417)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.0 0.4 GO:0019884 antigen processing and presentation of exogenous antigen(GO:0019884)
0.0 0.4 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.1 GO:0045842 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.5 GO:1900078 positive regulation of cellular response to insulin stimulus(GO:1900078)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.2 GO:0070992 translation initiation complex(GO:0070992)
0.1 0.2 GO:0014801 longitudinal sarcoplasmic reticulum(GO:0014801)
0.1 0.4 GO:0000805 X chromosome(GO:0000805)
0.1 0.3 GO:1990795 lateral part of cell(GO:0097574) basolateral part of cell(GO:1990794) rod bipolar cell terminal bouton(GO:1990795)
0.1 0.2 GO:0000814 ESCRT II complex(GO:0000814)
0.1 0.2 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.6 GO:0031415 NatA complex(GO:0031415)
0.0 0.3 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.1 GO:0044302 dentate gyrus mossy fiber(GO:0044302)
0.0 0.2 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.3 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.6 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.3 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.6 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.3 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.3 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.1 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.1 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.7 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.0 GO:0005656 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.0 0.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.1 GO:0044218 growing cell tip(GO:0035838) other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.4 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.3 GO:0046930 pore complex(GO:0046930)
0.0 0.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.7 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.2 GO:0042555 MCM complex(GO:0042555)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.2 0.5 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.2 0.5 GO:0004454 ketohexokinase activity(GO:0004454)
0.1 0.4 GO:0052594 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.1 0.4 GO:0004658 propionyl-CoA carboxylase activity(GO:0004658)
0.1 0.7 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 0.3 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.1 0.7 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 0.4 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 0.3 GO:0004370 glycerol kinase activity(GO:0004370)
0.1 0.6 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.1 0.4 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.1 0.3 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 0.3 GO:0036470 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478)
0.1 0.3 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.1 0.2 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1 0.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0016784 3-mercaptopyruvate sulfurtransferase activity(GO:0016784)
0.0 0.1 GO:0036004 GAF domain binding(GO:0036004)
0.0 0.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.4 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.1 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 0.6 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.2 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.1 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.0 0.2 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.4 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.3 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.2 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.1 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0 0.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.6 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.4 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.0 0.5 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.8 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.0 GO:0038052 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.4 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.0 0.9 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.2 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.2 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.3 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.1 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.1 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 1.1 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.7 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.3 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.4 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.7 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.4 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.4 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.1 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.7 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.3 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter