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avrg: GFI1 WT vs 36n/n vs KD

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Results for Lef1

Z-value: 0.96

Motif logo

Transcription factors associated with Lef1

Gene Symbol Gene ID Gene Info
ENSMUSG00000027985.15 lymphoid enhancer binding factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Lef1mm39_v1_chr3_+_130906434_1309064520.791.1e-01Click!

Activity profile of Lef1 motif

Sorted Z-values of Lef1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_18053158 1.04 ENSMUST00000066885.6
SKI/DACH domain containing 1
chr14_-_98406977 1.01 ENSMUST00000071533.13
ENSMUST00000069334.8
dachshund family transcription factor 1
chr19_-_30526916 0.70 ENSMUST00000025803.9
dickkopf WNT signaling pathway inhibitor 1
chr9_-_49710058 0.64 ENSMUST00000192584.2
ENSMUST00000166811.9
neural cell adhesion molecule 1
chr9_-_48747232 0.62 ENSMUST00000093852.5
zinc finger and BTB domain containing 16
chr13_-_54835460 0.61 ENSMUST00000129881.8
ring finger protein 44
chr15_-_58078274 0.58 ENSMUST00000022986.8
F-box protein 32
chr10_-_95159933 0.55 ENSMUST00000053594.7
CASP2 and RIPK1 domain containing adaptor with death domain
chr6_-_99073156 0.51 ENSMUST00000175886.8
forkhead box P1
chr9_-_49710190 0.51 ENSMUST00000114476.8
ENSMUST00000193547.6
neural cell adhesion molecule 1
chr9_-_48747474 0.48 ENSMUST00000216150.2
zinc finger and BTB domain containing 16
chr2_-_34261121 0.48 ENSMUST00000127353.3
ENSMUST00000141653.3
pre B cell leukemia homeobox 3
chr7_+_48895879 0.46 ENSMUST00000064395.13
neuron navigator 2
chrX_-_133062677 0.46 ENSMUST00000033611.5
X-linked Kx blood group related, X-linked
chr1_-_140111138 0.46 ENSMUST00000111976.9
ENSMUST00000066859.13
complement component factor h
chr8_+_109441276 0.45 ENSMUST00000043896.10
zinc finger homeobox 3
chr1_-_140111018 0.39 ENSMUST00000192880.6
ENSMUST00000111977.8
complement component factor h
chr2_-_18053595 0.39 ENSMUST00000142856.2
SKI/DACH domain containing 1
chr6_-_99005835 0.38 ENSMUST00000154163.9
forkhead box P1
chr6_-_52141796 0.36 ENSMUST00000014848.11
homeobox A2
chr10_-_12745109 0.35 ENSMUST00000218635.2
utrophin
chr1_+_39940189 0.35 ENSMUST00000191761.6
ENSMUST00000193682.6
ENSMUST00000195860.6
ENSMUST00000195259.6
ENSMUST00000195636.6
ENSMUST00000192509.6
mitogen-activated protein kinase kinase kinase kinase 4
chr7_+_26895206 0.35 ENSMUST00000179391.8
ENSMUST00000108379.8
cDNA sequence BC024978
chrX_+_128650486 0.35 ENSMUST00000167619.9
ENSMUST00000037854.15
diaphanous related formin 2
chr11_+_108811168 0.34 ENSMUST00000052915.14
axin 2
chr10_+_85763545 0.34 ENSMUST00000170396.3
achaete-scute family bHLH transcription factor 4
chr17_-_32503107 0.33 ENSMUST00000237692.2
bromodomain containing 4
chr8_-_85526653 0.33 ENSMUST00000126806.2
ENSMUST00000076715.13
nuclear factor I/X
chr11_+_87959067 0.33 ENSMUST00000018521.11
vascular endothelial zinc finger 1
chr1_-_135615831 0.33 ENSMUST00000190298.8
neuron navigator 1
chr9_+_119978773 0.32 ENSMUST00000068698.15
ENSMUST00000215512.2
ENSMUST00000111627.3
ENSMUST00000093773.8
myelin-associated oligodendrocytic basic protein
chr13_-_54835508 0.32 ENSMUST00000177950.8
ENSMUST00000146931.8
ring finger protein 44
chr7_+_27878894 0.31 ENSMUST00000085901.13
ENSMUST00000172761.8
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr3_+_53371086 0.31 ENSMUST00000058577.5
proline and serine rich 1
chr2_+_90912710 0.29 ENSMUST00000169852.2
spleen focus forming virus (SFFV) proviral integration oncogene
chr4_-_63321591 0.29 ENSMUST00000035724.5
AT-hook transcription factor
chrX_+_158623460 0.27 ENSMUST00000112451.8
ENSMUST00000112453.9
SH3-domain kinase binding protein 1
chr17_-_32503060 0.27 ENSMUST00000003726.16
ENSMUST00000121285.8
ENSMUST00000120276.9
bromodomain containing 4
chr12_+_85043262 0.27 ENSMUST00000101202.10
YLP motif containing 1
chr15_-_50753437 0.26 ENSMUST00000077935.6
transcriptional repressor GATA binding 1
chr16_+_32090286 0.26 ENSMUST00000093183.5
single-pass membrane protein with coiled-coil domains 1
chr7_-_26895561 0.25 ENSMUST00000122202.8
ENSMUST00000080356.10
small nuclear ribonucleoprotein polypeptide A
chr13_+_38010879 0.25 ENSMUST00000149745.8
ras responsive element binding protein 1
chrX_+_128650579 0.25 ENSMUST00000113320.3
diaphanous related formin 2
chr4_-_123558516 0.25 ENSMUST00000147030.2
microtubule-actin crosslinking factor 1
chr2_-_156154667 0.25 ENSMUST00000079125.8
SCAN domain-containing 1
chr16_-_89940652 0.25 ENSMUST00000114124.9
T cell lymphoma invasion and metastasis 1
chr5_+_150119860 0.24 ENSMUST00000202600.4
FRY microtubule binding protein
chr15_-_66432938 0.24 ENSMUST00000048372.7
transmembrane protein 71
chr2_-_27365612 0.24 ENSMUST00000147736.2
bromodomain containing 3
chrX_+_158491589 0.24 ENSMUST00000080394.13
SH3-domain kinase binding protein 1
chr12_+_76593799 0.24 ENSMUST00000218380.2
ENSMUST00000219751.2
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr1_+_166828982 0.24 ENSMUST00000165874.8
ENSMUST00000190081.7
family with sequence similarity 78, member B
chr14_+_47536075 0.24 ENSMUST00000227554.2
mitogen-activated protein kinase 1 interacting protein 1-like
chr2_-_69416365 0.24 ENSMUST00000100051.9
ENSMUST00000092551.5
ENSMUST00000080953.12
low density lipoprotein receptor-related protein 2
chr8_+_89247976 0.23 ENSMUST00000034086.13
naked cuticle 1
chr8_+_66419809 0.23 ENSMUST00000072482.13
membrane associated ring-CH-type finger 1
chr5_+_16758538 0.23 ENSMUST00000199581.5
hepatocyte growth factor
chr2_-_60503998 0.23 ENSMUST00000059888.15
ENSMUST00000154764.2
integrin beta 6
chr12_+_85043083 0.23 ENSMUST00000168977.8
ENSMUST00000021670.15
YLP motif containing 1
chr11_-_77380492 0.23 ENSMUST00000037593.14
ENSMUST00000092892.10
ankyrin repeat domain 13b
chr8_+_108669276 0.23 ENSMUST00000220518.2
zinc finger homeobox 3
chr15_+_102885467 0.23 ENSMUST00000001706.7
homeobox C9
chr4_-_123421441 0.22 ENSMUST00000147228.8
microtubule-actin crosslinking factor 1
chrX_+_152281200 0.22 ENSMUST00000060714.10
ubiquilin 2
chr7_+_27879650 0.22 ENSMUST00000172467.8
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr3_-_75864195 0.22 ENSMUST00000038563.14
ENSMUST00000167078.8
ENSMUST00000117242.8
golgi integral membrane protein 4
chr16_-_4831349 0.22 ENSMUST00000201077.2
ENSMUST00000202281.4
ENSMUST00000090453.9
ENSMUST00000023191.17
rogdi homolog
chr15_-_50753061 0.22 ENSMUST00000165201.9
ENSMUST00000184458.8
transcriptional repressor GATA binding 1
chr15_+_81350538 0.21 ENSMUST00000230219.2
ring-box 1
chr5_-_132570710 0.21 ENSMUST00000182974.9
autism susceptibility candidate 2
chr8_+_40964818 0.21 ENSMUST00000098817.4
vacuolar protein sorting 37A
chr5_+_16758777 0.21 ENSMUST00000030683.8
hepatocyte growth factor
chr1_+_55445033 0.21 ENSMUST00000042986.10
phospholipase C-like 1
chr8_+_85807566 0.21 ENSMUST00000140621.2
WD repeat domain 83 opposite strand
chr5_+_53748323 0.21 ENSMUST00000201883.4
recombination signal binding protein for immunoglobulin kappa J region
chr17_+_26633794 0.20 ENSMUST00000182897.8
ENSMUST00000183077.8
ENSMUST00000053020.8
neuralized E3 ubiquitin protein ligase 1B
chr9_-_51076724 0.20 ENSMUST00000210433.2
predicted gene, 32742
chr18_+_82932747 0.20 ENSMUST00000071233.7
zinc finger protein 516
chr12_-_84265609 0.20 ENSMUST00000046266.13
ENSMUST00000220974.2
mitotic deacetylase associated SANT domain protein
chr8_+_85807369 0.19 ENSMUST00000079764.14
WD repeat domain 83 opposite strand
chr1_+_136059101 0.19 ENSMUST00000075164.11
kinesin family member 21B
chr1_+_132119169 0.19 ENSMUST00000188169.7
ENSMUST00000112357.9
ENSMUST00000188175.2
LEM domain containing 1
predicted gene, 29695
chr6_-_52211882 0.19 ENSMUST00000125581.2
homeobox A10
chr5_-_136596094 0.19 ENSMUST00000175975.9
ENSMUST00000176216.9
ENSMUST00000176745.8
cut-like homeobox 1
chr11_-_104332528 0.19 ENSMUST00000106971.2
KAT8 regulatory NSL complex subunit 1
chr17_+_74835290 0.19 ENSMUST00000180037.8
baculoviral IAP repeat-containing 6
chr9_+_72832904 0.19 ENSMUST00000038489.6
pygopus 1
chr5_+_77414031 0.19 ENSMUST00000113449.2
RE1-silencing transcription factor
chr15_-_98769056 0.19 ENSMUST00000178486.9
ENSMUST00000023741.16
lysine (K)-specific methyltransferase 2D
chrX_-_142716200 0.19 ENSMUST00000112851.8
ENSMUST00000112856.3
ENSMUST00000033642.10
doublecortin
chr10_-_85847697 0.18 ENSMUST00000105304.2
ENSMUST00000061699.12
BPI fold containing family C
chr2_+_92015780 0.18 ENSMUST00000128781.9
ENSMUST00000111291.9
PHD finger protein 21A
chr4_+_116415251 0.18 ENSMUST00000106475.2
GC-rich promoter binding protein 1-like 1
chr7_-_29204812 0.18 ENSMUST00000183096.8
ENSMUST00000085809.11
signal-induced proliferation-associated 1 like 3
chr8_-_11362731 0.18 ENSMUST00000033898.10
collagen, type IV, alpha 1
chr11_+_78006391 0.18 ENSMUST00000155571.2
family with sequence similarity 222, member B
chr3_+_130904000 0.18 ENSMUST00000029611.14
ENSMUST00000106341.9
ENSMUST00000066849.13
lymphoid enhancer binding factor 1
chr16_+_17269845 0.18 ENSMUST00000006293.5
ENSMUST00000231228.2
v-crk avian sarcoma virus CT10 oncogene homolog-like
chr10_+_66932235 0.18 ENSMUST00000174317.8
jumonji domain containing 1C
chr10_-_60055082 0.18 ENSMUST00000135158.9
carbohydrate sulfotransferase 3
chrX_-_156198282 0.17 ENSMUST00000079945.11
ENSMUST00000138396.3
phosphate regulating endopeptidase homolog, X-linked
chr7_-_26895141 0.17 ENSMUST00000163311.9
ENSMUST00000126211.2
small nuclear ribonucleoprotein polypeptide A
chr19_-_4384029 0.17 ENSMUST00000176653.2
lysine (K)-specific demethylase 2A
chr15_-_71906051 0.17 ENSMUST00000159993.8
collagen, type XXII, alpha 1
chr12_+_71095112 0.16 ENSMUST00000135709.2
AT rich interactive domain 4A (RBP1-like)
chr9_+_61280764 0.16 ENSMUST00000160541.8
ENSMUST00000161207.8
ENSMUST00000159630.8
transducin-like enhancer of split 3
chr15_-_50753792 0.16 ENSMUST00000185183.2
transcriptional repressor GATA binding 1
chrX_+_101048650 0.16 ENSMUST00000144753.2
NHS-like 2
chr1_+_135074520 0.16 ENSMUST00000027684.11
ADP-ribosylation factor-like 8A
chr8_+_45960804 0.16 ENSMUST00000067065.14
ENSMUST00000124544.8
ENSMUST00000138049.9
ENSMUST00000132139.9
sorbin and SH3 domain containing 2
chr17_+_74835417 0.16 ENSMUST00000182944.8
ENSMUST00000182597.8
ENSMUST00000182133.8
ENSMUST00000183224.8
baculoviral IAP repeat-containing 6
chr7_-_73187369 0.16 ENSMUST00000172704.6
chromodomain helicase DNA binding protein 2
chr4_-_151946124 0.16 ENSMUST00000169423.9
calmodulin binding transcription activator 1
chr14_+_58308004 0.16 ENSMUST00000165526.9
fibroblast growth factor 9
chr18_+_4921663 0.16 ENSMUST00000143254.8
supervillin
chr2_+_146063841 0.16 ENSMUST00000089257.6
insulinoma-associated 1
chrX_-_163041185 0.15 ENSMUST00000112265.9
BMX non-receptor tyrosine kinase
chrX_-_72868544 0.15 ENSMUST00000002080.12
ENSMUST00000114438.3
PDZ domain containing 4
chr11_+_117223161 0.15 ENSMUST00000106349.2
septin 9
chr3_+_7568481 0.15 ENSMUST00000051064.9
ENSMUST00000193010.2
zinc finger, C2HC-type containing 1A
chr9_-_103639018 0.15 ENSMUST00000215136.2
ENSMUST00000189588.7
transmembrane protein 108
chr9_-_103638985 0.15 ENSMUST00000189066.2
transmembrane protein 108
chr10_+_79984097 0.15 ENSMUST00000099492.10
ENSMUST00000042057.12
midnolin
chr19_-_14575395 0.15 ENSMUST00000052011.15
ENSMUST00000167776.3
transducin-like enhancer of split 4
chr2_+_18059982 0.14 ENSMUST00000028076.15
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10
chr8_+_88978600 0.14 ENSMUST00000154115.2
terminal nucleotidyltransferase 4B
chr11_+_79551358 0.14 ENSMUST00000155381.2
RAB11 family interacting protein 4 (class II)
chr19_-_5779648 0.14 ENSMUST00000116558.3
ENSMUST00000099955.4
ENSMUST00000161368.2
family with sequence similarity 89, member B
chr11_+_108814007 0.14 ENSMUST00000106711.2
axin 2
chr16_+_95058417 0.14 ENSMUST00000113861.8
ENSMUST00000113854.8
ENSMUST00000113862.8
ENSMUST00000037154.14
ENSMUST00000113855.8
potassium inwardly-rectifying channel, subfamily J, member 15
chr1_+_131671751 0.13 ENSMUST00000049027.10
solute carrier family 26, member 9
chr1_-_156766351 0.13 ENSMUST00000189648.2
Ral GEF with PH domain and SH3 binding motif 2
chr11_+_6339442 0.13 ENSMUST00000109786.8
zinc finger, MIZ-type containing 2
chr4_-_20778847 0.13 ENSMUST00000102998.4
Na+/K+ transporting ATPase interacting 3
chr16_+_19916292 0.13 ENSMUST00000023509.5
ENSMUST00000232088.2
ENSMUST00000231842.2
kelch-like 24
chr1_+_64572050 0.13 ENSMUST00000190348.2
cAMP responsive element binding protein 1
chr6_+_17463819 0.13 ENSMUST00000140070.8
met proto-oncogene
chr6_+_15185202 0.13 ENSMUST00000154448.2
forkhead box P2
chr8_+_95720864 0.13 ENSMUST00000212141.2
adhesion G protein-coupled receptor G1
chr13_+_42205790 0.13 ENSMUST00000220525.2
human immunodeficiency virus type I enhancer binding protein 1
chr13_+_89687915 0.13 ENSMUST00000022108.9
hyaluronan and proteoglycan link protein 1
chr2_-_65068960 0.12 ENSMUST00000112429.9
ENSMUST00000102726.8
ENSMUST00000112430.8
Cobl-like 1
chr5_-_71253107 0.12 ENSMUST00000197284.5
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2
chr8_+_95721378 0.12 ENSMUST00000212956.2
ENSMUST00000212531.2
adhesion G protein-coupled receptor G1
chr7_+_107649900 0.12 ENSMUST00000214599.2
ENSMUST00000209805.3
olfactory receptor 479
chr11_+_6339330 0.12 ENSMUST00000012612.11
zinc finger, MIZ-type containing 2
chr14_-_36628263 0.12 ENSMUST00000183007.2
coiled-coil serine rich 2
chr6_-_97436223 0.12 ENSMUST00000113359.8
FERM domain containing 4B
chr9_+_61280890 0.12 ENSMUST00000161689.8
transducin-like enhancer of split 3
chr13_+_83672965 0.12 ENSMUST00000199432.5
ENSMUST00000198069.5
ENSMUST00000197681.5
ENSMUST00000197722.5
ENSMUST00000197938.5
myocyte enhancer factor 2C
chrX_-_16777913 0.12 ENSMUST00000040134.8
Norrie disease (pseudoglioma) (human)
chr8_+_95721019 0.12 ENSMUST00000212976.2
ENSMUST00000212995.2
adhesion G protein-coupled receptor G1
chr15_-_82796308 0.12 ENSMUST00000109510.10
ENSMUST00000048966.7
transcription factor 20
chr9_+_109961079 0.12 ENSMUST00000197480.5
ENSMUST00000197984.5
ENSMUST00000199896.2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr19_+_8568618 0.12 ENSMUST00000170817.2
ENSMUST00000010251.11
solute carrier family 22 (organic anion transporter), member 8
chr4_-_151946155 0.11 ENSMUST00000049790.14
calmodulin binding transcription activator 1
chr3_-_108117754 0.11 ENSMUST00000117784.8
ENSMUST00000119650.8
ENSMUST00000117409.8
ataxin 7-like 2
chr17_+_48717007 0.11 ENSMUST00000167180.8
ENSMUST00000046651.7
ENSMUST00000233426.2
O-acyl-ADP-ribose deacylase 1
chr17_-_33979280 0.11 ENSMUST00000173860.8
RAB11B, member RAS oncogene family
chr1_-_156766381 0.11 ENSMUST00000188656.7
Ral GEF with PH domain and SH3 binding motif 2
chrX_-_37653396 0.11 ENSMUST00000016681.15
cullin 4B
chr1_+_42734051 0.11 ENSMUST00000239323.2
ENSMUST00000199521.5
ENSMUST00000176807.3
POU domain, class 3, transcription factor 3
predicted gene 20646
chr1_+_180468895 0.11 ENSMUST00000192725.6
lin-9 homolog (C. elegans)
chr12_-_72283465 0.11 ENSMUST00000021497.16
ENSMUST00000137990.2
reticulon 1
chr17_-_33979442 0.11 ENSMUST00000057373.14
RAB11B, member RAS oncogene family
chr3_+_101917455 0.11 ENSMUST00000066187.6
ENSMUST00000198675.2
nescient helix loop helix 2
chr11_-_102815910 0.11 ENSMUST00000021311.10
kinesin family member 18B
chr2_+_136555364 0.10 ENSMUST00000028727.11
ENSMUST00000110098.4
synaptosomal-associated protein 25
chr8_+_40964830 0.10 ENSMUST00000238339.2
vacuolar protein sorting 37A
chr7_-_78228116 0.10 ENSMUST00000206268.2
ENSMUST00000039431.14
neurotrophic tyrosine kinase, receptor, type 3
chr5_+_77413282 0.10 ENSMUST00000080359.12
RE1-silencing transcription factor
chr9_+_109961048 0.10 ENSMUST00000088716.12
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr14_-_100521888 0.10 ENSMUST00000226774.2
Kruppel-like factor 12
chr15_+_81350497 0.10 ENSMUST00000023036.7
ring-box 1
chr13_+_81031512 0.10 ENSMUST00000099356.10
arrestin domain containing 3
chr5_-_136596299 0.10 ENSMUST00000004097.16
cut-like homeobox 1
chr3_+_101917392 0.10 ENSMUST00000196324.2
nescient helix loop helix 2
chr19_-_27988534 0.10 ENSMUST00000174850.8
regulatory factor X, 3 (influences HLA class II expression)
chr15_-_50746202 0.10 ENSMUST00000184885.8
transcriptional repressor GATA binding 1
chr2_-_170248421 0.10 ENSMUST00000154650.8
breast carcinoma amplified sequence 1
chr18_+_65022035 0.10 ENSMUST00000224385.3
ENSMUST00000163516.9
neural precursor cell expressed, developmentally down-regulated gene 4-like
chr9_+_21527462 0.10 ENSMUST00000034707.15
ENSMUST00000098948.10
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr13_+_35925296 0.10 ENSMUST00000163595.3
chromodomain protein, Y chromosome-like
chr11_+_45946800 0.10 ENSMUST00000011400.8
a disintegrin and metallopeptidase domain 19 (meltrin beta)
chr15_-_98851423 0.10 ENSMUST00000134214.3
predicted gene, 49450
chr2_+_96148418 0.10 ENSMUST00000135431.8
ENSMUST00000162807.9
leucine rich repeat containing 4C
chr2_+_156154508 0.10 ENSMUST00000073942.12
ENSMUST00000109580.2
cyclic nucleotide binding domain containing 2
chr14_-_71004019 0.10 ENSMUST00000167242.8
exportin 7
chr14_+_26761023 0.09 ENSMUST00000223942.2
interleukin 17 receptor D
chr5_-_51711237 0.09 ENSMUST00000132734.8
peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
chr6_+_54016543 0.09 ENSMUST00000046856.14
chimerin 2
chr4_-_141325517 0.09 ENSMUST00000131317.8
ENSMUST00000006381.11
ENSMUST00000129602.8
filamin binding LIM protein 1
chr7_-_110681402 0.09 ENSMUST00000159305.2
eukaryotic translation initiation factor 4, gamma 2
chr17_-_48716756 0.09 ENSMUST00000160319.8
ENSMUST00000159535.2
ENSMUST00000078800.13
ENSMUST00000046719.14
ENSMUST00000162460.8
nuclear transcription factor-Y alpha
chr11_-_52174129 0.09 ENSMUST00000109071.3
transcription factor 7, T cell specific
chr11_+_70323452 0.09 ENSMUST00000084954.13
ENSMUST00000108568.10
ENSMUST00000079056.9
ENSMUST00000102564.11
ENSMUST00000124943.8
ENSMUST00000150076.8
ENSMUST00000102563.2
arrestin, beta 2
chr10_-_13264574 0.09 ENSMUST00000079698.7
phosphatase and actin regulator 2
chr12_-_31763859 0.09 ENSMUST00000057783.6
ENSMUST00000236002.2
ENSMUST00000174480.3
ENSMUST00000176710.2
G protein-coupled receptor 22
chr2_+_172863688 0.09 ENSMUST00000029014.16
RNA binding motif protein 38

Network of associatons between targets according to the STRING database.

First level regulatory network of Lef1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0001928 regulation of exocyst assembly(GO:0001928)
0.2 0.7 GO:0090081 regulation of heart induction by regulation of canonical Wnt signaling pathway(GO:0090081)
0.2 0.6 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.2 1.0 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.1 0.7 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 1.1 GO:0042078 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1 0.3 GO:1904266 regulation of Schwann cell chemotaxis(GO:1904266) positive regulation of Schwann cell chemotaxis(GO:1904268) Schwann cell chemotaxis(GO:1990751)
0.1 0.9 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 0.8 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.1 0.4 GO:0021658 rhombomere 3 morphogenesis(GO:0021658)
0.1 0.5 GO:0032423 regulation of mismatch repair(GO:0032423) regulation of chondrocyte development(GO:0061181) negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.1 0.2 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.1 0.3 GO:2000705 regulation of dense core granule biogenesis(GO:2000705)
0.1 0.5 GO:0021564 vagus nerve development(GO:0021564)
0.1 0.2 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.1 0.3 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.1 0.2 GO:0098582 innate vocalization behavior(GO:0098582)
0.1 0.2 GO:0003358 noradrenergic neuron development(GO:0003358)
0.0 0.3 GO:0007527 adult somatic muscle development(GO:0007527)
0.0 0.6 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.1 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.0 0.1 GO:1904550 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 0.2 GO:0032696 negative regulation of interleukin-13 production(GO:0032696) trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.2 GO:0045054 constitutive secretory pathway(GO:0045054)
0.0 0.2 GO:1905066 Notch signaling pathway involved in heart induction(GO:0003137) regulation of Notch signaling pathway involved in heart induction(GO:0035480) positive regulation of Notch signaling pathway involved in heart induction(GO:0035481) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of heart induction(GO:1901321) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.0 GO:0099545 trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.0 0.1 GO:1904633 glomerular visceral epithelial cell apoptotic process(GO:1903210) regulation of glomerular visceral epithelial cell apoptotic process(GO:1904633) positive regulation of glomerular visceral epithelial cell apoptotic process(GO:1904635) positive regulation of progesterone biosynthetic process(GO:2000184)
0.0 0.6 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 0.1 GO:0072233 ascending thin limb development(GO:0072021) thick ascending limb development(GO:0072023) metanephric ascending thin limb development(GO:0072218) metanephric thick ascending limb development(GO:0072233)
0.0 0.2 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.6 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0 0.1 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.0 0.2 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.0 0.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.2 GO:1902661 DNA methylation on cytosine within a CG sequence(GO:0010424) regulation of glucose mediated signaling pathway(GO:1902659) positive regulation of glucose mediated signaling pathway(GO:1902661)
0.0 0.3 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.1 GO:0034635 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.0 0.1 GO:0090327 negative regulation of locomotion involved in locomotory behavior(GO:0090327)
0.0 0.1 GO:0046022 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.0 0.8 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.3 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.1 GO:0048687 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
0.0 0.2 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 0.2 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.0 0.1 GO:1900477 negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter(GO:1900477)
0.0 0.1 GO:0046684 response to pyrethroid(GO:0046684)
0.0 0.1 GO:0002071 glandular epithelial cell maturation(GO:0002071)
0.0 0.2 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.0 0.1 GO:1905006 positive regulation of activation-induced cell death of T cells(GO:0070237) negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905006)
0.0 0.5 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0 0.2 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.0 0.2 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.2 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.5 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.1 GO:1904207 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0 0.2 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.0 0.1 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.1 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.0 0.2 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.2 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.0 0.3 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.4 GO:0021707 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.0 GO:0048022 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.0 0.1 GO:2000328 regulation of T-helper 17 cell lineage commitment(GO:2000328)
0.0 0.1 GO:0033153 somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
0.0 0.1 GO:1901377 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) negative regulation of vascular associated smooth muscle cell migration(GO:1904753)
0.0 0.2 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.0 0.2 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.4 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.3 GO:0070571 negative regulation of neuron projection regeneration(GO:0070571)
0.0 0.2 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.2 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0 0.1 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.1 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.0 0.1 GO:0060983 epicardium-derived cardiac endothelial cell differentiation(GO:0003349) epicardium-derived cardiac vascular smooth muscle cell differentiation(GO:0060983)
0.0 0.2 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.0 GO:0017085 response to insecticide(GO:0017085)
0.0 0.8 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.2 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.4 GO:0045116 protein neddylation(GO:0045116)
0.0 0.0 GO:0098964 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
0.0 0.0 GO:0032487 cerebellar cortex structural organization(GO:0021698) regulation of Rap protein signal transduction(GO:0032487) negative regulation of integrin activation(GO:0033624)
0.0 0.0 GO:0003257 positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257) mesoderm migration involved in gastrulation(GO:0007509)
0.0 0.4 GO:0090162 establishment of epithelial cell polarity(GO:0090162)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.0 0.6 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.2 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.0 0.1 GO:1990844 subsarcolemmal mitochondrion(GO:1990843) interfibrillar mitochondrion(GO:1990844)
0.0 0.1 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.4 GO:0097451 glial limiting end-foot(GO:0097451)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.0 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.0 0.2 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.3 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.3 GO:0060091 kinocilium(GO:0060091)
0.0 0.6 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0 0.2 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.2 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.4 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.3 GO:0070938 contractile ring(GO:0070938)
0.0 0.1 GO:0033269 internode region of axon(GO:0033269)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.1 GO:0000235 astral microtubule(GO:0000235)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
0.1 0.8 GO:0001851 complement component C3b binding(GO:0001851)
0.1 1.0 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 0.4 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 0.2 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.1 1.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 0.7 GO:0048019 receptor antagonist activity(GO:0048019)
0.1 0.4 GO:0004111 creatine kinase activity(GO:0004111)
0.0 1.2 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.2 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.0 0.1 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 0.1 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.0 0.4 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.1 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.2 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.6 GO:0070513 death domain binding(GO:0070513)
0.0 0.2 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.1 GO:0031699 beta-3 adrenergic receptor binding(GO:0031699)
0.0 0.5 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.3 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.1 GO:0005118 sevenless binding(GO:0005118)
0.0 0.1 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0 0.2 GO:0043996 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.3 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.1 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 0.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.2 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.5 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.0 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.1 GO:0015651 quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.0 0.1 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004) neurotrophin receptor activity(GO:0005030)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.1 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 1.7 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.5 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.4 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.7 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.3 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 1.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.4 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.4 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway