Project

avrg: GFI1 WT vs 36n/n vs KD

Navigation
Downloads

Results for Lhx8

Z-value: 0.91

Motif logo

logo of

Transcription factors associated with Lhx8

Gene Symbol Gene ID Gene Info
Lhx8
ENSMUSG00000096225.8 LIM homeobox protein 8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Lhx8mm39_v1_chr3_-_154036180_1540362960.828.8e-02Click!

Activity profile of Lhx8 motif

Sorted Z-values of Lhx8 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_44258112 1.64 ENSMUST00000054801.4
Mettl21e
methyltransferase like 21E
chr16_-_48592372 0.77 ENSMUST00000231701.3
Trat1
T cell receptor associated transmembrane adaptor 1
chr7_+_103379581 0.70 ENSMUST00000098193.4
Olfr628
olfactory receptor 628
chrX_-_156198282 0.63 ENSMUST00000079945.11
ENSMUST00000138396.3
Phex
phosphate regulating endopeptidase homolog, X-linked
chr7_+_140261864 0.61 ENSMUST00000214637.3
Olfr45
olfactory receptor 45
chr14_+_54862762 0.61 ENSMUST00000097177.5
Psmb11
proteasome (prosome, macropain) subunit, beta type, 11
chr14_+_51648277 0.59 ENSMUST00000159674.4
ENSMUST00000163019.9
ENSMUST00000233394.2
ENSMUST00000232951.2
ENSMUST00000232797.2
ENSMUST00000233766.2
ENSMUST00000233848.2
ENSMUST00000233280.2
ENSMUST00000233920.2
ENSMUST00000233126.2
ENSMUST00000233651.2
Vmn2r88
vomeronasal 2, receptor 88
chr9_-_40004854 0.58 ENSMUST00000050996.6
ENSMUST00000213087.4
Olfr983
olfactory receptor 983
chr4_-_155729865 0.57 ENSMUST00000115821.3
Gm10563
predicted gene 10563
chr9_+_38164070 0.54 ENSMUST00000213129.2
Olfr143
olfactory receptor 143
chr7_-_12002196 0.51 ENSMUST00000227973.2
ENSMUST00000228764.2
ENSMUST00000228482.2
ENSMUST00000227080.2
Vmn1r81
vomeronasal 1 receptor 81
chr8_+_105558204 0.48 ENSMUST00000059449.7
Ces2b
carboxyesterase 2B
chr5_-_62923463 0.47 ENSMUST00000076623.8
ENSMUST00000159470.3
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr1_+_92545510 0.46 ENSMUST00000213247.2
Olfr12
olfactory receptor 12
chr9_+_38202403 0.43 ENSMUST00000216276.2
ENSMUST00000215219.2
Olfr896-ps1
olfactory receptor 896, pseudogene 1
chr6_+_15185202 0.40 ENSMUST00000154448.2
Foxp2
forkhead box P2
chr7_-_106709576 0.40 ENSMUST00000215713.2
Olfr715b
olfactory receptor 715B
chr2_-_87838612 0.39 ENSMUST00000215457.2
Olfr1160
olfactory receptor 1160
chr19_-_12302465 0.38 ENSMUST00000207241.3
Olfr1437
olfactory receptor 1437
chr16_+_24540599 0.37 ENSMUST00000115314.4
Lpp
LIM domain containing preferred translocation partner in lipoma
chr19_+_13208692 0.36 ENSMUST00000207246.4
Olfr1463
olfactory receptor 1463
chr2_+_36263531 0.35 ENSMUST00000072114.4
ENSMUST00000217511.2
Olfr338
olfactory receptor 338
chr10_-_4382311 0.35 ENSMUST00000126102.8
ENSMUST00000131853.2
ENSMUST00000042251.11
Rmnd1
required for meiotic nuclear division 1 homolog
chr2_+_85545763 0.35 ENSMUST00000216443.3
Olfr1009
olfactory receptor 1009
chr10_-_129577771 0.34 ENSMUST00000215142.3
ENSMUST00000213239.2
Olfr806
olfactory receptor 806
chr17_-_47143214 0.33 ENSMUST00000233537.2
Bicral
BRD4 interacting chromatin remodeling complex associated protein like
chr4_-_95965767 0.32 ENSMUST00000030305.13
ENSMUST00000107078.9
Cyp2j13
cytochrome P450, family 2, subfamily j, polypeptide 13
chr11_-_73382303 0.31 ENSMUST00000119863.2
ENSMUST00000215358.2
ENSMUST00000214623.2
Olfr381
olfactory receptor 381
chr10_-_4382283 0.31 ENSMUST00000155172.8
Rmnd1
required for meiotic nuclear division 1 homolog
chr2_+_89842475 0.31 ENSMUST00000214382.2
ENSMUST00000217065.3
Olfr1263
olfactory receptor 1263
chr17_+_33848054 0.29 ENSMUST00000166627.8
ENSMUST00000073570.12
ENSMUST00000170225.3
Zfp414
zinc finger protein 414
chr2_-_111880531 0.29 ENSMUST00000213582.2
ENSMUST00000213961.3
ENSMUST00000215531.2
Olfr1312
olfactory receptor 1312
chr2_-_36782948 0.29 ENSMUST00000217215.3
Olfr353
olfactory receptor 353
chr7_+_43701714 0.28 ENSMUST00000079859.7
Klk1b27
kallikrein 1-related peptidase b27
chr11_+_110858842 0.26 ENSMUST00000180023.8
ENSMUST00000106636.8
Kcnj16
potassium inwardly-rectifying channel, subfamily J, member 16
chr3_-_144466602 0.25 ENSMUST00000059091.6
Clca3a1
chloride channel accessory 3A1
chr2_-_104680104 0.25 ENSMUST00000028593.11
Prrg4
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr7_+_12711760 0.24 ENSMUST00000108535.8
ENSMUST00000108537.8
ENSMUST00000045810.15
Zfp446
zinc finger protein 446
chr14_+_24540745 0.23 ENSMUST00000112384.10
Rps24
ribosomal protein S24
chr11_-_109886601 0.23 ENSMUST00000020948.15
Abca8b
ATP-binding cassette, sub-family A (ABC1), member 8b
chr7_-_106563137 0.23 ENSMUST00000213552.2
ENSMUST00000040983.6
ENSMUST00000213651.2
Olfr6
olfactory receptor 6
chrY_-_2663658 0.22 ENSMUST00000091178.2
Sry
sex determining region of Chr Y
chr1_+_163875783 0.22 ENSMUST00000027874.6
Sele
selectin, endothelial cell
chr12_-_56583582 0.22 ENSMUST00000001536.9
Nkx2-1
NK2 homeobox 1
chr14_-_30213408 0.21 ENSMUST00000112250.6
Cacna1d
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr17_-_24851581 0.20 ENSMUST00000226398.2
ENSMUST00000226284.2
ENSMUST00000097373.2
ENSMUST00000228412.2
Tsc2
TSC complex subunit 2
chr2_-_120867232 0.19 ENSMUST00000023987.6
Epb42
erythrocyte membrane protein band 4.2
chr3_-_57599956 0.19 ENSMUST00000238789.2
ENSMUST00000197088.5
ENSMUST00000099091.4
Ankub1
ankrin repeat and ubiquitin domain containing 1
chr12_-_113379925 0.19 ENSMUST00000194162.6
ENSMUST00000192250.2
Ighd
immunoglobulin heavy constant delta
chr7_-_28071658 0.18 ENSMUST00000094644.11
Plekhg2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr17_-_24851549 0.17 ENSMUST00000227607.2
ENSMUST00000227509.2
ENSMUST00000227745.2
Tsc2
TSC complex subunit 2
chr7_-_104677667 0.17 ENSMUST00000215899.2
ENSMUST00000214318.3
Olfr675
olfactory receptor 675
chr15_-_98118858 0.17 ENSMUST00000142443.8
ENSMUST00000170618.8
Gm44579
Olfr287
predicted gene 44579
olfactory receptor 287
chr12_+_112940086 0.16 ENSMUST00000165079.8
ENSMUST00000221500.2
ENSMUST00000221104.2
ENSMUST00000002880.7
ENSMUST00000222209.2
Btbd6
BTB (POZ) domain containing 6
chr5_-_109207435 0.16 ENSMUST00000164875.3
Vmn2r11
vomeronasal 2, receptor 11
chr2_+_73142945 0.15 ENSMUST00000090811.11
ENSMUST00000112050.2
Scrn3
secernin 3
chr7_-_28071919 0.15 ENSMUST00000119990.8
Plekhg2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr16_+_35361635 0.15 ENSMUST00000120756.8
Sema5b
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B
chr8_+_72973560 0.14 ENSMUST00000003123.10
Fam32a
family with sequence similarity 32, member A
chr12_+_84034628 0.14 ENSMUST00000021649.8
Acot2
acyl-CoA thioesterase 2
chr14_-_36628263 0.13 ENSMUST00000183007.2
Ccser2
coiled-coil serine rich 2
chr7_-_104628324 0.13 ENSMUST00000217091.2
ENSMUST00000210963.3
Olfr671
olfactory receptor 671
chr4_+_19818718 0.13 ENSMUST00000035890.8
Slc7a13
solute carrier family 7, (cationic amino acid transporter, y+ system) member 13
chr13_-_21744063 0.12 ENSMUST00000217519.2
Olfr1535
olfactory receptor 1535
chr1_+_33947250 0.12 ENSMUST00000183034.5
Dst
dystonin
chr19_-_17333972 0.12 ENSMUST00000174236.8
Gcnt1
glucosaminyl (N-acetyl) transferase 1, core 2
chr3_+_116653113 0.11 ENSMUST00000040260.11
Frrs1
ferric-chelate reductase 1
chr5_-_31337193 0.11 ENSMUST00000201428.2
ENSMUST00000201468.4
ENSMUST00000101411.6
Gtf3c2
Gm29609
general transcription factor IIIC, polypeptide 2, beta
predicted gene 29609
chr7_-_28072022 0.10 ENSMUST00000144700.8
Plekhg2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr9_-_78285942 0.10 ENSMUST00000034900.8
Ooep
oocyte expressed protein
chr10_+_129184719 0.09 ENSMUST00000213970.2
Olfr782
olfactory receptor 782
chr6_-_136150491 0.09 ENSMUST00000111905.8
ENSMUST00000152012.8
ENSMUST00000143943.8
ENSMUST00000125905.2
Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr5_+_125080504 0.09 ENSMUST00000197746.2
Rflna
refilin A
chr14_+_73380485 0.09 ENSMUST00000170677.8
ENSMUST00000167401.8
Rcbtb2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr2_+_172994841 0.09 ENSMUST00000029017.6
Pck1
phosphoenolpyruvate carboxykinase 1, cytosolic
chr14_+_73380163 0.09 ENSMUST00000170368.8
ENSMUST00000171767.8
ENSMUST00000163533.8
Rcbtb2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr3_+_107198528 0.09 ENSMUST00000029502.14
Slc16a4
solute carrier family 16 (monocarboxylic acid transporters), member 4
chr10_+_129219952 0.09 ENSMUST00000214064.2
Olfr784
olfactory receptor 784
chr4_-_129015682 0.09 ENSMUST00000139450.8
ENSMUST00000125931.9
ENSMUST00000116444.10
Hpca
hippocalcin
chr9_+_118931532 0.08 ENSMUST00000165231.8
ENSMUST00000140326.8
Dlec1
deleted in lung and esophageal cancer 1
chr12_-_114621406 0.07 ENSMUST00000192077.2
Ighv1-15
immunoglobulin heavy variable 1-15
chr1_+_21310821 0.07 ENSMUST00000121676.8
ENSMUST00000124990.3
Gsta3
glutathione S-transferase, alpha 3
chr5_+_124068728 0.07 ENSMUST00000094320.10
ENSMUST00000165148.4
Ccdc62
coiled-coil domain containing 62
chr5_-_139115417 0.07 ENSMUST00000026973.14
Prkar1b
protein kinase, cAMP dependent regulatory, type I beta
chr19_-_34579356 0.07 ENSMUST00000168254.3
Ifit1bl1
interferon induced protein with tetratricpeptide repeats 1B like 1
chr7_-_3218968 0.07 ENSMUST00000171749.3
AU018091
expressed sequence AU018091
chr3_-_72964276 0.07 ENSMUST00000192477.2
Slitrk3
SLIT and NTRK-like family, member 3
chr14_+_73380577 0.06 ENSMUST00000165567.8
ENSMUST00000022702.13
Rcbtb2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr1_-_74627264 0.06 ENSMUST00000066986.13
Zfp142
zinc finger protein 142
chr15_-_99717956 0.06 ENSMUST00000109024.9
Lima1
LIM domain and actin binding 1
chr2_-_88562710 0.06 ENSMUST00000213118.2
Olfr1197
olfactory receptor 1197
chr12_-_115766700 0.06 ENSMUST00000196587.5
ENSMUST00000103543.3
Ighv1-74
immunoglobulin heavy variable V1-74
chr14_+_73380539 0.06 ENSMUST00000169513.8
ENSMUST00000165727.8
Rcbtb2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr17_-_90395771 0.06 ENSMUST00000197268.5
ENSMUST00000173917.8
Nrxn1
neurexin I
chr2_+_112114906 0.05 ENSMUST00000053666.8
Slc12a6
solute carrier family 12, member 6
chr7_+_19093665 0.05 ENSMUST00000140836.8
Ppp1r13l
protein phosphatase 1, regulatory subunit 13 like
chr3_+_130411097 0.05 ENSMUST00000166187.8
ENSMUST00000072271.13
Etnppl
ethanolamine phosphate phospholyase
chr12_-_113928438 0.04 ENSMUST00000103478.4
Ighv3-1
immunoglobulin heavy variable 3-1
chr6_+_67701864 0.04 ENSMUST00000103304.3
Igkv1-133
immunoglobulin kappa variable 1-133
chr7_-_19093383 0.03 ENSMUST00000047036.10
Cd3eap
CD3E antigen, epsilon polypeptide associated protein
chr18_+_68470616 0.03 ENSMUST00000172148.4
ENSMUST00000239469.2
Mc5r
melanocortin 5 receptor
chr7_-_59654849 0.03 ENSMUST00000059305.17
Snrpn
small nuclear ribonucleoprotein N
chr13_-_62706325 0.03 ENSMUST00000076195.7
ENSMUST00000101547.12
ENSMUST00000222852.2
ENSMUST00000220648.2
ENSMUST00000222429.2
ENSMUST00000222746.2
Zfp935
Zfp934
zinc finger protein 935
zinc finger protein 934
chr1_+_161796748 0.03 ENSMUST00000111594.3
ENSMUST00000028021.7
ENSMUST00000193784.2
ENSMUST00000161826.2
Pigc
Gm38304
phosphatidylinositol glycan anchor biosynthesis, class C
predicted gene, 38304
chr6_+_67586695 0.02 ENSMUST00000103303.3
Igkv1-135
immunoglobulin kappa variable 1-135
chr13_+_23431304 0.02 ENSMUST00000235331.2
ENSMUST00000236495.2
ENSMUST00000238002.2
Vmn1r223
vomeronasal 1 receptor 223
chr6_+_15184630 0.02 ENSMUST00000115470.3
Foxp2
forkhead box P2
chr5_-_123620632 0.02 ENSMUST00000198901.2
Il31
interleukin 31
chr13_+_65660492 0.02 ENSMUST00000081471.3
Gm10139
predicted gene 10139
chr13_-_62614608 0.01 ENSMUST00000223247.2
ENSMUST00000221747.2
Gm49359
predicted gene, 49359
chr13_-_66375387 0.01 ENSMUST00000167981.3
Gm10772
predicted gene 10772
chr16_-_58647137 0.01 ENSMUST00000215069.2
ENSMUST00000079955.6
Olfr175
olfactory receptor 175
chr14_+_118504372 0.01 ENSMUST00000171107.3
Gm9376
predicted gene 9376
chr15_+_54609011 0.01 ENSMUST00000050027.9
Ccn3
cellular communication network factor 3
chr1_+_180878797 0.01 ENSMUST00000036819.7
9130409I23Rik
RIKEN cDNA 9130409I23 gene
chr5_+_137551774 0.00 ENSMUST00000136088.8
ENSMUST00000139395.8
Actl6b
actin-like 6B
chr11_-_73290321 0.00 ENSMUST00000131253.2
ENSMUST00000120303.9
Olfr1
olfactory receptor 1
chr19_-_11313471 0.00 ENSMUST00000056035.9
ENSMUST00000067532.11
Ms4a7
membrane-spanning 4-domains, subfamily A, member 7
chr6_-_130258891 0.00 ENSMUST00000112020.2
Klra10
killer cell lectin-like receptor subfamily A, member 10

Network of associatons between targets according to the STRING database.

First level regulatory network of Lhx8

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 0.4 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.1 0.2 GO:0021759 globus pallidus development(GO:0021759)
0.1 0.7 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.2 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.0 0.1 GO:1900158 negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.0 0.1 GO:0030827 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
0.0 0.6 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.4 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0 0.1 GO:0061402 glycerol biosynthetic process(GO:0006114) positive regulation of transcription from RNA polymerase II promoter in response to acidic pH(GO:0061402)
0.0 0.1 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.1 GO:1901377 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377)
0.0 0.1 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.0 0.1 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.2 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.2 GO:0030238 male sex determination(GO:0030238)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.2 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.8 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.6 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.1 GO:0031673 H zone(GO:0031673)
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0086059 voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059)
0.0 0.1 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.0 0.1 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.6 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.2 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.0 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.0 0.2 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0 0.1 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.1 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
0.0 0.2 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.1 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.8 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling