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avrg: GFI1 WT vs 36n/n vs KD

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Results for Mbd2

Z-value: 1.47

Motif logo

Transcription factors associated with Mbd2

Gene Symbol Gene ID Gene Info
ENSMUSG00000024513.17 methyl-CpG binding domain protein 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Mbd2mm39_v1_chr18_+_70701260_707014690.976.6e-03Click!

Activity profile of Mbd2 motif

Sorted Z-values of Mbd2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_125681577 1.63 ENSMUST00000073935.7
GSG1-like
chr5_+_146321757 1.28 ENSMUST00000016143.9
WASP family, member 3
chr9_+_45924120 1.18 ENSMUST00000120463.9
ENSMUST00000120247.8
SIK family kinase 3
chr4_+_137004793 1.04 ENSMUST00000045747.5
wingless-type MMTV integration site family, member 4
chr2_+_28082943 1.00 ENSMUST00000113920.8
olfactomedin 1
chr2_+_28083105 0.92 ENSMUST00000100244.10
olfactomedin 1
chr2_-_27365612 0.78 ENSMUST00000147736.2
bromodomain containing 3
chr6_-_35110560 0.73 ENSMUST00000202143.4
ENSMUST00000114993.9
ENSMUST00000114989.9
ENSMUST00000044163.10
ENSMUST00000202417.2
CCR4-NOT transcription complex, subunit 4
chr6_-_38852899 0.70 ENSMUST00000160360.2
homeodomain interacting protein kinase 2
chr6_-_38852857 0.68 ENSMUST00000162359.8
homeodomain interacting protein kinase 2
chr19_+_10502612 0.62 ENSMUST00000237321.2
ENSMUST00000038379.5
cleavage and polyadenylation specific factor 7
chr1_-_74163575 0.61 ENSMUST00000169786.8
ENSMUST00000212888.2
ENSMUST00000191104.7
tensin 1
chr5_+_123532819 0.61 ENSMUST00000111596.8
ENSMUST00000068237.12
MLX interacting protein
chr11_+_77873535 0.61 ENSMUST00000108360.8
ENSMUST00000049167.14
PHD finger protein 12
chr11_-_107685383 0.59 ENSMUST00000021066.4
calcium channel, voltage-dependent, gamma subunit 4
chr10_-_7831657 0.59 ENSMUST00000147938.2
TGF-beta activated kinase 1/MAP3K7 binding protein 2
chr6_-_83433357 0.57 ENSMUST00000186548.7
tet methylcytosine dioxygenase 3
chr1_-_165830187 0.56 ENSMUST00000184643.8
ENSMUST00000160908.8
ENSMUST00000027850.15
ENSMUST00000160260.9
POU domain, class 2, transcription factor 1
chr6_-_99005212 0.55 ENSMUST00000177437.8
ENSMUST00000177229.8
ENSMUST00000124058.8
forkhead box P1
chr14_+_45457168 0.55 ENSMUST00000227086.2
ENSMUST00000147957.2
G protein-coupled receptor 137C
chr19_+_10502679 0.54 ENSMUST00000235674.2
cleavage and polyadenylation specific factor 7
chr12_-_99359265 0.54 ENSMUST00000177451.8
forkhead box N3
chr11_-_77380492 0.52 ENSMUST00000037593.14
ENSMUST00000092892.10
ankyrin repeat domain 13b
chr18_-_25301729 0.52 ENSMUST00000148255.8
tubulin polyglutamylase complex subunit 2
chr3_-_107240989 0.51 ENSMUST00000061772.11
RNA binding motif protein 15
chr4_+_44756608 0.51 ENSMUST00000143385.2
zinc finger, CCHC domain containing 7
chr7_+_100355910 0.50 ENSMUST00000207875.2
ENSMUST00000208013.2
family with sequence similarity 168, member A
chr4_+_42949814 0.49 ENSMUST00000037872.10
ENSMUST00000098112.9
DnaJ heat shock protein family (Hsp40) member B5
chr6_-_38853097 0.48 ENSMUST00000161779.8
homeodomain interacting protein kinase 2
chr13_-_40887244 0.48 ENSMUST00000110193.9
transcription factor AP-2, alpha
chr15_-_98769056 0.47 ENSMUST00000178486.9
ENSMUST00000023741.16
lysine (K)-specific methyltransferase 2D
chr13_+_55097200 0.47 ENSMUST00000026994.14
ENSMUST00000109994.9
unc-5 netrin receptor A
chr18_-_80756273 0.46 ENSMUST00000078049.12
ENSMUST00000236711.2
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1
chr10_-_77738300 0.46 ENSMUST00000057608.5
leucine rich repeat containing 3
chr17_-_66079629 0.46 ENSMUST00000233258.2
RAB31, member RAS oncogene family
chr9_+_45924105 0.46 ENSMUST00000126865.8
SIK family kinase 3
chr10_+_127216459 0.46 ENSMUST00000166820.8
R3H domain containing 2
chr11_-_107022940 0.45 ENSMUST00000106763.8
ENSMUST00000106762.8
bromodomain PHD finger transcription factor
chr2_+_32536594 0.44 ENSMUST00000113272.8
ENSMUST00000009705.14
ENSMUST00000167841.8
endoglin
chr14_+_99536111 0.44 ENSMUST00000005279.8
Kruppel-like factor 5
chr18_+_25302050 0.44 ENSMUST00000036619.14
ENSMUST00000165400.8
ENSMUST00000097643.10
expressed sequence AW554918
chr11_-_115977755 0.44 ENSMUST00000074628.13
ENSMUST00000106444.4
WW domain binding protein 2
chr1_-_165830160 0.42 ENSMUST00000111429.11
ENSMUST00000176800.2
ENSMUST00000177358.8
POU domain, class 2, transcription factor 1
chr7_+_5054514 0.42 ENSMUST00000069324.7
zinc finger protein 580
chr16_+_27207722 0.42 ENSMUST00000039443.14
ENSMUST00000096127.11
coiled-coil domain containing 50
chr15_-_75438457 0.42 ENSMUST00000163116.8
ENSMUST00000023241.12
lymphocyte antigen 6 complex, locus H
chr4_+_115594951 0.41 ENSMUST00000106522.9
EF-hand calcium binding domain 14
chr17_+_29833822 0.41 ENSMUST00000234498.2
ring finger protein 8
chr11_-_106811507 0.41 ENSMUST00000103067.10
SMAD specific E3 ubiquitin protein ligase 2
chr9_-_54858282 0.40 ENSMUST00000054018.7
cDNA sequence AY074887
chr19_-_10502468 0.40 ENSMUST00000025570.8
ENSMUST00000236455.2
succinate dehydrogenase complex assembly factor 2
chr9_-_107512566 0.40 ENSMUST00000055704.12
guanine nucleotide binding protein (G protein), alpha inhibiting 2
chr15_+_81469538 0.39 ENSMUST00000068387.11
E1A binding protein p300
chr12_+_3856510 0.38 ENSMUST00000172719.8
DNA methyltransferase 3A
chr1_-_63153414 0.38 ENSMUST00000153992.2
ENSMUST00000165066.8
ENSMUST00000172416.8
ENSMUST00000137511.8
INO80 complex subunit D
chr5_+_54155871 0.38 ENSMUST00000201469.4
stromal interaction molecule 2
chr4_-_3938352 0.37 ENSMUST00000003369.10
pleiomorphic adenoma gene 1
chr2_-_160714904 0.37 ENSMUST00000109460.8
ENSMUST00000127201.2
zinc fingers and homeoboxes 3
chr12_-_72455708 0.37 ENSMUST00000078505.14
reticulon 1
chr11_-_50183129 0.37 ENSMUST00000059458.5
mastermind like transcriptional coactivator 1
chr9_-_107512511 0.37 ENSMUST00000192615.6
ENSMUST00000192837.2
ENSMUST00000193876.2
guanine nucleotide binding protein (G protein), alpha inhibiting 2
chr3_-_27765381 0.36 ENSMUST00000193779.2
fibronectin type III domain containing 3B
chr13_-_120252229 0.36 ENSMUST00000223812.2
zinc finger protein 131
chr1_-_38168801 0.36 ENSMUST00000195383.2
REV1, DNA directed polymerase
chr11_+_103061905 0.35 ENSMUST00000042286.12
ENSMUST00000218163.2
formin-like 1
chr11_+_107438751 0.35 ENSMUST00000100305.8
ENSMUST00000075012.8
ENSMUST00000106746.8
helicase with zinc finger domain
chr10_+_127216668 0.35 ENSMUST00000111628.9
R3H domain containing 2
chr4_+_8690398 0.35 ENSMUST00000127476.8
chromodomain helicase DNA binding protein 7
chr8_+_27575611 0.34 ENSMUST00000178514.8
ENSMUST00000033876.14
adhesion G protein-coupled receptor A2
chr2_-_94236991 0.34 ENSMUST00000111237.9
ENSMUST00000094801.5
ENSMUST00000111238.8
tetratricopeptide repeat domain 17
chr16_+_20335712 0.34 ENSMUST00000003318.13
ENSMUST00000171572.9
dishevelled segment polarity protein 3
chr17_+_44499451 0.34 ENSMUST00000024755.7
chloride intracellular channel 5
chr4_-_136563154 0.34 ENSMUST00000105846.9
ENSMUST00000059287.14
ENSMUST00000105845.9
Eph receptor B2
chr9_+_43655230 0.34 ENSMUST00000034510.9
nectin cell adhesion molecule 1
chr7_+_135253659 0.33 ENSMUST00000209979.2
protein tyrosine phosphatase, receptor type, E
chr10_+_95350975 0.32 ENSMUST00000099329.5
ubiquitin-conjugating enzyme E2N
chr16_+_94129279 0.32 ENSMUST00000023660.9
ripply transcriptional repressor 3
chr14_+_75521783 0.31 ENSMUST00000022577.6
ENSMUST00000227049.2
zinc finger CCCH type containing 13
chr4_+_44756553 0.31 ENSMUST00000107824.9
zinc finger, CCHC domain containing 7
chr11_+_78006391 0.31 ENSMUST00000155571.2
family with sequence similarity 222, member B
chr4_+_43669266 0.31 ENSMUST00000107864.8
transmembrane protein 8B
chr19_+_6291698 0.30 ENSMUST00000045351.13
autophagy related 2A
chr17_-_16046780 0.30 ENSMUST00000232638.2
ENSMUST00000170578.3
repulsive guidance molecule family member B
chr11_-_106811185 0.30 ENSMUST00000167787.2
ENSMUST00000092517.9
SMAD specific E3 ubiquitin protein ligase 2
chrX_+_72716756 0.30 ENSMUST00000033752.14
ENSMUST00000114467.9
solute carrier family 6 (neurotransmitter transporter, creatine), member 8
chr18_+_53995260 0.29 ENSMUST00000237880.2
casein kinase 1, gamma 3
chr5_+_73071897 0.29 ENSMUST00000200785.2
SLAIN motif family, member 2
chr9_+_121548469 0.29 ENSMUST00000182225.8
natural killer tumor recognition sequence
chr12_+_111679689 0.29 ENSMUST00000040519.12
ENSMUST00000163220.10
ENSMUST00000162316.2
cytochrome c oxidase assembly factor 8
chr19_-_4447080 0.29 ENSMUST00000075856.11
ENSMUST00000176483.3
ENSMUST00000116571.9
lysine (K)-specific demethylase 2A
chr7_-_29979758 0.29 ENSMUST00000108190.8
WD repeat domain 62
chr14_+_34542053 0.29 ENSMUST00000043349.7
glutamate receptor, ionotropic, delta 1
chr18_-_84607615 0.28 ENSMUST00000125763.3
zinc finger protein 407
chr4_+_115594918 0.27 ENSMUST00000106525.9
EF-hand calcium binding domain 14
chr13_+_113130374 0.27 ENSMUST00000092089.6
multiciliate differentiation and DNA synthesis associated cell cycle protein
chr4_-_128699838 0.27 ENSMUST00000106072.9
ENSMUST00000170934.3
zinc finger protein 362
chr12_+_112978051 0.26 ENSMUST00000223502.2
ENSMUST00000084891.5
ENSMUST00000220541.2
phosphofurin acidic cluster sorting protein 2
chr9_+_108569489 0.26 ENSMUST00000195405.6
protein kinase, cAMP dependent regulatory, type II alpha
chr5_-_25703700 0.26 ENSMUST00000173073.8
ENSMUST00000045291.14
ENSMUST00000173174.2
lysine (K)-specific methyltransferase 2C
chr5_+_30745447 0.26 ENSMUST00000066295.5
potassium channel, subfamily K, member 3
chr8_-_123980908 0.25 ENSMUST00000122363.8
VPS9 domain containing 1
chr5_+_54155814 0.25 ENSMUST00000117661.9
stromal interaction molecule 2
chr19_+_4147391 0.25 ENSMUST00000174514.2
ENSMUST00000174149.8
CDK2-associated protein 2
chr11_-_107022748 0.25 ENSMUST00000057892.15
bromodomain PHD finger transcription factor
chr7_+_4693603 0.25 ENSMUST00000120836.8
BR serine/threonine kinase 1
chr2_-_160714473 0.24 ENSMUST00000103111.9
zinc fingers and homeoboxes 3
chr2_-_181335767 0.24 ENSMUST00000002532.9
regulator of G-protein signaling 19
chr2_+_128809268 0.24 ENSMUST00000110320.9
ENSMUST00000110319.3
zinc finger CCCH type containing 6
chr11_-_86884507 0.24 ENSMUST00000018571.5
yippee like 2
chr7_+_24982206 0.24 ENSMUST00000165239.3
capicua transcriptional repressor
chr7_+_29931309 0.24 ENSMUST00000019882.16
ENSMUST00000149654.8
polymerase (RNA) II (DNA directed) polypeptide I
chr8_+_106024294 0.23 ENSMUST00000015003.10
E2F transcription factor 4
chr18_-_16942289 0.23 ENSMUST00000025166.14
cadherin 2
chr9_-_108067552 0.23 ENSMUST00000035208.14
bassoon
chr17_-_45047521 0.23 ENSMUST00000113572.9
runt related transcription factor 2
chr19_-_5323092 0.23 ENSMUST00000237463.2
ENSMUST00000025786.9
phosphofurin acidic cluster sorting protein 1
chr17_+_83522700 0.23 ENSMUST00000170794.8
protein kinase domain containing, cytoplasmic
chr4_-_66322750 0.23 ENSMUST00000068214.11
astrotactin 2
chr15_-_99355623 0.23 ENSMUST00000023747.14
NCK-associated protein 5-like
chr7_+_79675727 0.23 ENSMUST00000049680.10
zinc finger protein 710
chr15_-_97729341 0.22 ENSMUST00000079838.14
ENSMUST00000118294.8
histone deacetylase 7
chr2_-_181335697 0.22 ENSMUST00000108779.8
ENSMUST00000108769.8
ENSMUST00000108772.8
regulator of G-protein signaling 19
chr18_-_6490808 0.22 ENSMUST00000028100.13
ENSMUST00000050542.6
enhancer of polycomb homolog 1
chr16_+_58490625 0.22 ENSMUST00000060077.7
coproporphyrinogen oxidase
chr16_+_20335825 0.22 ENSMUST00000171774.2
dishevelled segment polarity protein 3
chr15_+_74435587 0.21 ENSMUST00000185682.7
ENSMUST00000170845.8
ENSMUST00000187599.2
adhesion G protein-coupled receptor B1
chrX_+_150927237 0.21 ENSMUST00000168786.8
ENSMUST00000112605.8
ENSMUST00000112604.8
IQ motif and Sec7 domain 2
chr15_+_75781584 0.21 ENSMUST00000192937.2
tigger transposable element derived 5
chr15_-_28025920 0.21 ENSMUST00000090247.7
triple functional domain (PTPRF interacting)
chr10_-_81266800 0.21 ENSMUST00000117966.2
nuclear factor I/C
chr4_+_132766793 0.21 ENSMUST00000105914.2
AT hook, DNA binding motif, containing 1
chr11_-_5394838 0.21 ENSMUST00000109867.8
ENSMUST00000143746.3
zinc and ring finger 3
chr13_+_54651592 0.20 ENSMUST00000121401.8
ENSMUST00000118072.8
ENSMUST00000159721.2
SUMO-interacting motifs containing 1
chrX_-_12628309 0.20 ENSMUST00000096495.11
ENSMUST00000076016.6
mediator complex subunit 14
chr10_-_79602764 0.20 ENSMUST00000047203.9
ring finger protein 126
chr7_+_4693759 0.20 ENSMUST00000048248.9
BR serine/threonine kinase 1
chr8_-_123980825 0.20 ENSMUST00000118279.2
VPS9 domain containing 1
chr11_+_79230618 0.20 ENSMUST00000219057.2
ENSMUST00000108251.9
ENSMUST00000071325.9
neurofibromin 1
chr11_+_77384234 0.20 ENSMUST00000037285.10
ENSMUST00000100812.4
GIT ArfGAP 1
chr17_+_6157154 0.20 ENSMUST00000149756.8
tubby like protein 4
chr17_-_10538253 0.19 ENSMUST00000233828.2
ENSMUST00000233645.2
ENSMUST00000042296.9
quaking, KH domain containing RNA binding
chr17_+_48047955 0.19 ENSMUST00000086932.10
transcription factor EB
chr5_+_64960705 0.19 ENSMUST00000165536.8
Kruppel-like factor 3 (basic)
chr15_-_64184485 0.18 ENSMUST00000177083.8
ENSMUST00000177371.8
ArfGAP with SH3 domain, ankyrin repeat and PH domain1
chr19_-_5738936 0.18 ENSMUST00000113615.9
pecanex homolog 3
chr5_-_147337162 0.18 ENSMUST00000049324.13
FMS-like tyrosine kinase 3
chr5_+_137286535 0.18 ENSMUST00000024099.11
ENSMUST00000196208.5
ENSMUST00000085934.4
acetylcholinesterase
chr4_+_42950367 0.18 ENSMUST00000084662.12
DnaJ heat shock protein family (Hsp40) member B5
chr7_+_25386418 0.17 ENSMUST00000002678.10
transforming growth factor, beta 1
chr17_+_34251041 0.17 ENSMUST00000173354.9
retinoid X receptor beta
chr2_-_155849839 0.17 ENSMUST00000086145.10
ENSMUST00000144686.8
ENSMUST00000140657.8
RIKEN cDNA 6430550D23 gene
chr9_+_54858066 0.17 ENSMUST00000034848.14
proteasome subunit alpha 4
chr1_-_36597313 0.17 ENSMUST00000195339.3
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr7_+_132460954 0.17 ENSMUST00000084497.12
ENSMUST00000106161.8
BRISC complex subunit
chr9_+_61280501 0.16 ENSMUST00000162583.8
ENSMUST00000161993.8
ENSMUST00000160882.8
ENSMUST00000160724.8
ENSMUST00000162973.8
ENSMUST00000159050.8
transducin-like enhancer of split 3
chr16_-_20245071 0.16 ENSMUST00000115547.9
ENSMUST00000096199.5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr2_-_22930149 0.16 ENSMUST00000091394.13
ENSMUST00000093171.13
abl interactor 1
chr5_+_129578285 0.16 ENSMUST00000053737.9
splicing factor SWAP
chr9_+_108569315 0.16 ENSMUST00000035220.12
protein kinase, cAMP dependent regulatory, type II alpha
chr4_+_152181155 0.16 ENSMUST00000105661.10
ENSMUST00000084115.4
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr15_-_53209513 0.16 ENSMUST00000077273.9
exostosin glycosyltransferase 1
chr9_+_113760376 0.16 ENSMUST00000214095.2
ENSMUST00000116492.3
ENSMUST00000216558.2
upstream binding protein 1
chr18_-_25302064 0.16 ENSMUST00000115817.3
tubulin polyglutamylase complex subunit 2
chr7_-_65020955 0.15 ENSMUST00000102592.10
tight junction protein 1
chr9_+_61280764 0.15 ENSMUST00000160541.8
ENSMUST00000161207.8
ENSMUST00000159630.8
transducin-like enhancer of split 3
chr18_+_53995156 0.15 ENSMUST00000069597.8
casein kinase 1, gamma 3
chr8_-_73302068 0.15 ENSMUST00000058534.7
mediator complex subunit 26
chr17_+_34250757 0.15 ENSMUST00000044858.16
ENSMUST00000174299.9
retinoid X receptor beta
chr19_-_10502546 0.15 ENSMUST00000237827.2
succinate dehydrogenase complex assembly factor 2
chr7_+_79676095 0.15 ENSMUST00000206039.2
zinc finger protein 710
chr4_+_89576431 0.15 ENSMUST00000052478.3
doublesex and mab-3 related transcription factor like family A1
chr2_-_167334746 0.15 ENSMUST00000109211.9
ENSMUST00000057627.16
spermatogenesis associated 2
chr16_+_91444730 0.15 ENSMUST00000119368.8
ENSMUST00000114037.9
ENSMUST00000114036.9
ENSMUST00000122302.8
Son DNA binding protein
chr10_-_62628008 0.15 ENSMUST00000217768.2
ENSMUST00000020268.7
ENSMUST00000218946.2
ENSMUST00000219527.2
cell division cycle and apoptosis regulator 1
chr4_-_154245073 0.15 ENSMUST00000105639.4
ENSMUST00000030896.15
transformation related protein 63 regulated like
chr7_+_100355798 0.15 ENSMUST00000107042.9
ENSMUST00000207564.2
ENSMUST00000049053.9
family with sequence similarity 168, member A
chr1_+_36107452 0.15 ENSMUST00000088174.4
heparan sulfate 6-O-sulfotransferase 1
chr2_+_156455583 0.14 ENSMUST00000109567.10
ENSMUST00000169464.9
DLG associated protein 4
chr2_-_93164812 0.14 ENSMUST00000111265.9
tetraspanin 18
chr10_+_13841819 0.14 ENSMUST00000187083.7
human immunodeficiency virus type I enhancer binding protein 2
chr6_-_53797748 0.14 ENSMUST00000127748.5
TLR4 interactor with leucine-rich repeats
chr14_+_20757615 0.14 ENSMUST00000022358.9
ENSMUST00000224751.2
zinc finger SWIM-type containing 8
chr14_+_49303952 0.14 ENSMUST00000037473.6
ENSMUST00000228238.2
adaptor-related protein complex 5, mu 1 subunit
chr4_+_106768714 0.13 ENSMUST00000072753.13
ENSMUST00000097934.10
single-stranded DNA binding protein 3
chr19_-_47452557 0.13 ENSMUST00000111800.4
SH3 and PX domains 2A
chr11_-_72098239 0.13 ENSMUST00000238653.2
ENSMUST00000108505.2
RIKEN cDNA 4933427D14 gene
chr9_+_61280890 0.13 ENSMUST00000161689.8
transducin-like enhancer of split 3
chr17_+_86475205 0.13 ENSMUST00000097275.9
protein kinase C, epsilon
chr16_+_18166045 0.13 ENSMUST00000239533.1
ENSMUST00000239534.1
armadillo repeat deleted in velocardiofacial syndrome
chr15_+_99600475 0.13 ENSMUST00000228984.2
ENSMUST00000229845.2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr2_+_32766126 0.13 ENSMUST00000028135.15
niban apoptosis regulator 2
chr5_-_100126707 0.12 ENSMUST00000170912.2
heterogeneous nuclear ribonucleoprotein D
chr11_+_87959067 0.12 ENSMUST00000018521.11
vascular endothelial zinc finger 1
chr2_-_181335518 0.12 ENSMUST00000108776.8
ENSMUST00000108771.2
regulator of G-protein signaling 19
chr14_-_68362284 0.12 ENSMUST00000111089.8
ENSMUST00000022638.6
neurofilament, medium polypeptide
chr17_-_23959334 0.12 ENSMUST00000024702.5
progestin and adipoQ receptor family member IV
chr11_-_106378622 0.12 ENSMUST00000001059.9
ENSMUST00000106799.2
ENSMUST00000106800.2
endoplasmic reticulum (ER) to nucleus signalling 1
chr2_-_22930104 0.12 ENSMUST00000153931.8
ENSMUST00000123948.8
abl interactor 1
chr5_-_36641456 0.12 ENSMUST00000119916.2
ENSMUST00000031097.8
transcriptional adaptor 2B
chr9_+_44394080 0.12 ENSMUST00000220303.2
B cell CLL/lymphoma 9-like

Network of associatons between targets according to the STRING database.

First level regulatory network of Mbd2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:2000019 positive regulation of dermatome development(GO:0061184) renal vesicle induction(GO:0072034) negative regulation of male gonad development(GO:2000019)
0.2 1.9 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.2 1.0 GO:0071698 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.2 0.6 GO:1905053 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.2 1.9 GO:0023041 neuronal signal transduction(GO:0023041)
0.2 0.5 GO:0060854 patterning of lymph vessels(GO:0060854)
0.1 0.4 GO:1905072 detection of oxygen(GO:0003032) cardiac jelly development(GO:1905072)
0.1 0.7 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.1 0.6 GO:0097032 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.1 0.4 GO:0014737 positive regulation of muscle atrophy(GO:0014737)
0.1 0.6 GO:0044727 DNA demethylation of male pronucleus(GO:0044727)
0.1 0.3 GO:1904783 positive regulation of NMDA glutamate receptor activity(GO:1904783)
0.1 0.3 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.1 0.3 GO:0015881 creatine transport(GO:0015881)
0.1 0.5 GO:0003409 optic cup structural organization(GO:0003409)
0.1 0.6 GO:1904953 Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904953)
0.1 0.4 GO:0003162 atrioventricular node development(GO:0003162)
0.1 0.2 GO:0002572 pro-T cell differentiation(GO:0002572)
0.1 0.7 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.3 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1 0.1 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1 0.2 GO:0099526 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.1 0.4 GO:0009814 defense response, incompatible interaction(GO:0009814)
0.1 0.2 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 0.3 GO:0090210 regulation of establishment of blood-brain barrier(GO:0090210)
0.1 0.7 GO:1901250 regulation of lung goblet cell differentiation(GO:1901249) negative regulation of lung goblet cell differentiation(GO:1901250)
0.1 0.4 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.1 0.2 GO:0045212 neurotransmitter receptor biosynthetic process(GO:0045212)
0.1 0.8 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.1 0.5 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.2 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.0 0.1 GO:0097065 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.0 2.2 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.2 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 2.0 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.2 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.5 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.1 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.0 0.1 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.0 0.2 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0 0.4 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.4 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 1.2 GO:0031643 positive regulation of myelination(GO:0031643)
0.0 0.2 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997) negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.0 0.3 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.0 0.4 GO:1905144 acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 0.2 GO:0070054 activation of signaling protein activity involved in unfolded protein response(GO:0006987) mRNA splicing via endonucleolytic cleavage and ligation involved in unfolded protein response(GO:0030969) mRNA splicing, via endonucleolytic cleavage and ligation(GO:0070054) mRNA endonucleolytic cleavage involved in unfolded protein response(GO:0070055)
0.0 0.1 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.5 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.2 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.1 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.4 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.1 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.0 0.4 GO:0060736 prostate gland growth(GO:0060736)
0.0 0.2 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.1 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0 0.4 GO:0002934 desmosome organization(GO:0002934)
0.0 0.1 GO:1901355 response to rapamycin(GO:1901355)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.0 0.2 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.1 GO:0010725 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.0 0.1 GO:0032262 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) UMP salvage(GO:0044206) CMP metabolic process(GO:0046035)
0.0 0.4 GO:0051014 actin filament severing(GO:0051014)
0.0 0.6 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.2 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.0 0.3 GO:0002024 diet induced thermogenesis(GO:0002024)
0.0 0.4 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.0 0.4 GO:0060510 Type II pneumocyte differentiation(GO:0060510)
0.0 0.1 GO:0033182 regulation of histone ubiquitination(GO:0033182)
0.0 0.1 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.2 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.2 GO:0070417 cellular response to cold(GO:0070417)
0.0 0.3 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:2000667 positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-13 secretion(GO:2000667)
0.0 0.1 GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.0 0.3 GO:0044804 nucleophagy(GO:0044804)
0.0 0.2 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.1 GO:0045186 zonula adherens assembly(GO:0045186)
0.0 0.2 GO:0060179 male mating behavior(GO:0060179)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.3 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.2 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.2 GO:0072675 osteoclast fusion(GO:0072675)
0.0 0.0 GO:0021586 pons maturation(GO:0021586)
0.0 0.4 GO:0072673 lamellipodium morphogenesis(GO:0072673)
0.0 0.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.2 GO:0048714 positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0 0.3 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.0 0.4 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.2 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.0 0.4 GO:0007099 centriole replication(GO:0007099)
0.0 0.3 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.1 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.2 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.8 GO:0051865 protein autoubiquitination(GO:0051865)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.1 0.2 GO:1990257 piccolo-bassoon transport vesicle(GO:1990257)
0.1 0.2 GO:0060187 cell pole(GO:0060187)
0.1 0.2 GO:1990630 IRE1-RACK1-PP2A complex(GO:1990630)
0.1 1.5 GO:0032279 asymmetric synapse(GO:0032279)
0.1 0.8 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 2.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.7 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.6 GO:0001940 male pronucleus(GO:0001940)
0.0 0.6 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.4 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 0.6 GO:0016342 catenin complex(GO:0016342)
0.0 1.0 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.4 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0070847 core mediator complex(GO:0070847)
0.0 0.5 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.6 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.2 GO:0061574 ASAP complex(GO:0061574)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.9 GO:1990752 microtubule end(GO:1990752)
0.0 0.2 GO:0001739 sex chromatin(GO:0001739)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 1.8 GO:0016605 PML body(GO:0016605)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 0.2 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.4 GO:0035861 site of double-strand break(GO:0035861)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.2 GO:0046790 virion binding(GO:0046790)
0.1 0.3 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
0.1 0.5 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.1 0.6 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.6 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 0.4 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 0.2 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.1 0.5 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.2 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.3 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.1 GO:0035276 ethanol binding(GO:0035276)
0.0 0.6 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.2 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.0 0.4 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.2 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 1.8 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.0 0.8 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.4 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0005333 norepinephrine transmembrane transporter activity(GO:0005333)
0.0 0.6 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.8 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.1 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.0 0.2 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.2 GO:0045545 syndecan binding(GO:0045545)
0.0 0.2 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 1.0 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.2 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.5 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.8 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.2 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 1.2 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.3 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.2 GO:0071253 connexin binding(GO:0071253)
0.0 0.7 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.8 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.3 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.2 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.7 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.5 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.3 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.0 0.6 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 1.7 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 1.4 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 2.2 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.7 PID ATM PATHWAY ATM pathway
0.0 2.2 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.6 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.7 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.4 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.5 PID NETRIN PATHWAY Netrin-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 1.0 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 1.0 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.6 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.5 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.3 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.4 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.7 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.4 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.6 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.4 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.2 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.3 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.2 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.0 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.7 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.5 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors