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avrg: GFI1 WT vs 36n/n vs KD

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Results for Mef2d_Mef2a

Z-value: 3.05

Motif logo

Transcription factors associated with Mef2d_Mef2a

Gene Symbol Gene ID Gene Info
ENSMUSG00000001419.18 myocyte enhancer factor 2D
ENSMUSG00000030557.18 myocyte enhancer factor 2A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Mef2dmm39_v1_chr3_+_88049875_880498920.975.1e-03Click!
Mef2amm39_v1_chr7_-_67022520_670226090.791.1e-01Click!

Activity profile of Mef2d_Mef2a motif

Sorted Z-values of Mef2d_Mef2a motif

Promoter Log-likelihood Transcript Gene Gene Info
chr13_-_24118139 10.28 ENSMUST00000052776.4
H2B clustered histone 1
chr13_-_23946359 5.04 ENSMUST00000091701.3
H3 clustered histone 1
chr13_-_23882437 4.07 ENSMUST00000102967.3
H4 clustered histone 3
chr5_-_129030367 3.28 ENSMUST00000111346.6
ENSMUST00000200470.5
RIMS binding protein 2
chr6_+_122803624 2.99 ENSMUST00000203075.2
forkhead box J2
chr4_+_62581857 2.73 ENSMUST00000126338.2
regulator of G-protein signaling 3
chr15_+_101164719 2.54 ENSMUST00000230814.2
ENSMUST00000023779.8
nuclear receptor subfamily 4, group A, member 1
chr15_-_76116245 2.26 ENSMUST00000167754.8
plectin
chr3_-_142101339 2.17 ENSMUST00000198381.5
ENSMUST00000090134.12
ENSMUST00000196908.5
PDZ and LIM domain 5
chr11_-_69289052 2.03 ENSMUST00000050140.6
transmembrane protein 88
chr13_+_23868175 1.99 ENSMUST00000018246.6
H2B clustered histone 4
chr12_+_71095112 1.96 ENSMUST00000135709.2
AT rich interactive domain 4A (RBP1-like)
chr5_+_138278777 1.92 ENSMUST00000048028.15
ENSMUST00000162245.8
ENSMUST00000161691.2
stromal antigen 3
chr12_-_111638722 1.85 ENSMUST00000001304.9
creatine kinase, brain
chr2_-_33261411 1.80 ENSMUST00000131298.7
ENSMUST00000091039.5
ENSMUST00000042615.13
Ral GEF with PH domain and SH3 binding motif 1
chr10_-_127190280 1.74 ENSMUST00000059718.6
inhibin beta-E
chr2_+_11647610 1.74 ENSMUST00000028111.6
interleukin 2 receptor, alpha chain
chr5_+_138278502 1.73 ENSMUST00000160729.8
stromal antigen 3
chr5_+_105667254 1.65 ENSMUST00000067924.13
ENSMUST00000150981.2
leucine rich repeat containing 8 family, member C
chr6_+_116627567 1.65 ENSMUST00000067354.10
ENSMUST00000178241.4
DEPP1 autophagy regulator
chr2_-_33261498 1.62 ENSMUST00000113165.8
Ral GEF with PH domain and SH3 binding motif 1
chr14_-_20718337 1.61 ENSMUST00000057090.12
ENSMUST00000117386.2
synaptopodin 2-like
chr12_-_34956910 1.56 ENSMUST00000239321.2
histone deacetylase 9
chr7_-_127423641 1.56 ENSMUST00000106267.5
syntaxin 1B
chr2_+_3514071 1.55 ENSMUST00000036350.3
cerebral dopamine neurotrophic factor
chr1_-_64161415 1.48 ENSMUST00000135075.2
Kruppel-like factor 7 (ubiquitous)
chr17_-_36208265 1.47 ENSMUST00000148721.8
RIKEN cDNA 2310061I04 gene
chr11_+_31822211 1.45 ENSMUST00000020543.13
ENSMUST00000109412.9
cytoplasmic polyadenylation element binding protein 4
chr13_+_89687915 1.42 ENSMUST00000022108.9
hyaluronan and proteoglycan link protein 1
chr9_+_74860133 1.41 ENSMUST00000215370.2
family with sequence similarity 214, member A
chr9_-_49710058 1.38 ENSMUST00000192584.2
ENSMUST00000166811.9
neural cell adhesion molecule 1
chr9_-_107474221 1.36 ENSMUST00000238519.2
leucine-rich single-pass membrane protein 2
chr16_+_32090286 1.35 ENSMUST00000093183.5
single-pass membrane protein with coiled-coil domains 1
chr13_-_23867924 1.29 ENSMUST00000171127.4
H2A clustered histone 6
chr17_-_66079629 1.26 ENSMUST00000233258.2
RAB31, member RAS oncogene family
chr2_-_111965322 1.22 ENSMUST00000213696.2
olfactory receptor 1316
chr19_-_5974825 1.22 ENSMUST00000055458.6
CDC42 effector protein (Rho GTPase binding) 2
chr1_-_89942299 1.21 ENSMUST00000086882.8
ENSMUST00000097656.10
ankyrin repeat and SOCS box-containing 18
chr3_-_142101418 1.15 ENSMUST00000029941.16
ENSMUST00000058626.9
PDZ and LIM domain 5
chr19_-_34856853 1.14 ENSMUST00000036584.13
pantothenate kinase 1
chr9_-_49710190 1.12 ENSMUST00000114476.8
ENSMUST00000193547.6
neural cell adhesion molecule 1
chr14_-_51134930 1.11 ENSMUST00000227271.2
kelch-like 33
chr1_+_16758629 1.09 ENSMUST00000026881.11
lymphocyte antigen 96
chr19_+_38252984 1.08 ENSMUST00000198518.5
ENSMUST00000199812.5
leucine-rich repeat LGI family, member 1
chr13_-_32967937 1.07 ENSMUST00000238977.3
myosin light chain kinase family, member 4
chr7_+_27878894 1.05 ENSMUST00000085901.13
ENSMUST00000172761.8
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr2_+_71884943 1.05 ENSMUST00000028525.6
Rap guanine nucleotide exchange factor (GEF) 4
chr5_-_122752508 1.03 ENSMUST00000127220.8
ENSMUST00000031426.14
intraflagellar transport 81
chr14_+_47886748 1.02 ENSMUST00000190252.7
ENSMUST00000186466.3
kinectin 1
chr12_+_59177552 1.01 ENSMUST00000175877.8
MIA SH3 domain ER export factor 2
chr13_+_5911481 0.98 ENSMUST00000000080.8
Kruppel-like factor 6
chr11_-_78950698 0.94 ENSMUST00000141409.8
kinase suppressor of ras 1
chr2_+_19662529 0.92 ENSMUST00000052168.6
OTU domain containing 1
chr2_+_48839505 0.91 ENSMUST00000112745.8
ENSMUST00000112754.8
methyl-CpG binding domain protein 5
chr2_+_90927053 0.88 ENSMUST00000132741.3
spleen focus forming virus (SFFV) proviral integration oncogene
chr1_-_64160557 0.87 ENSMUST00000055001.10
ENSMUST00000114086.8
Kruppel-like factor 7 (ubiquitous)
chr17_+_75742881 0.86 ENSMUST00000164192.9
RAS, guanyl releasing protein 3
chr11_-_83483807 0.85 ENSMUST00000019071.4
chemokine (C-C motif) ligand 6
chr13_+_38010879 0.84 ENSMUST00000149745.8
ras responsive element binding protein 1
chr3_+_96484294 0.84 ENSMUST00000148290.2
predicted gene 16253
chr3_+_90511068 0.78 ENSMUST00000001046.7
S100 calcium binding protein A4
chr6_+_116627635 0.78 ENSMUST00000204555.2
DEPP1 autophagy regulator
chrX_+_72818003 0.78 ENSMUST00000002081.6
serine/arginine-rich protein specific kinase 3
chr18_-_25887173 0.78 ENSMUST00000225477.2
CUGBP, Elav-like family member 4
chr7_+_27879650 0.76 ENSMUST00000172467.8
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr5_-_51711237 0.75 ENSMUST00000132734.8
peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
chr4_-_128699838 0.75 ENSMUST00000106072.9
ENSMUST00000170934.3
zinc finger protein 362
chr9_-_101076198 0.74 ENSMUST00000066773.9
protein phosphatase 2, regulatory subunit B'', alpha
chr15_+_101152078 0.74 ENSMUST00000228985.2
nuclear receptor subfamily 4, group A, member 1
chr14_-_36641270 0.73 ENSMUST00000182797.8
coiled-coil serine rich 2
chr18_+_61096660 0.72 ENSMUST00000039904.7
calcium/calmodulin-dependent protein kinase II alpha
chr9_+_99511549 0.72 ENSMUST00000131095.8
ENSMUST00000078367.12
ENSMUST00000112885.9
DAZ interacting protein 1-like
chr9_+_77543776 0.72 ENSMUST00000057781.8
kelch-like 31
chr18_+_7905440 0.72 ENSMUST00000170854.2
WW domain containing adaptor with coiled-coil
chr6_+_137387718 0.72 ENSMUST00000167002.4
protein tyrosine phosphatase, receptor type, O
chr16_+_14523696 0.71 ENSMUST00000023356.8
snail family zinc finger 2
chr15_+_81469538 0.70 ENSMUST00000068387.11
E1A binding protein p300
chrX_-_48980360 0.70 ENSMUST00000217355.3
olfactory receptor 1322
chr10_-_69048928 0.69 ENSMUST00000170048.2
RIKEN cDNA A930033H14 gene
chr13_+_102830029 0.68 ENSMUST00000022124.10
ENSMUST00000171267.2
ENSMUST00000167144.2
ENSMUST00000170878.2
CD180 antigen
chr12_+_69288606 0.68 ENSMUST00000063445.13
kelch domain containing 1
chr2_+_30485048 0.68 ENSMUST00000102853.4
CSA-conditional, T cell activation-dependent protein
chr3_-_103645311 0.67 ENSMUST00000029440.10
olfactomedin-like 3
chr6_-_142647944 0.67 ENSMUST00000100827.5
ENSMUST00000087527.11
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr2_-_119371994 0.67 ENSMUST00000171024.8
exonuclease 3'-5' domain containing 1
chr17_+_44499451 0.67 ENSMUST00000024755.7
chloride intracellular channel 5
chr18_+_67597929 0.65 ENSMUST00000025411.9
PRELI domain containing 3A
chrX_-_63320543 0.65 ENSMUST00000114679.2
ENSMUST00000069926.14
SLIT and NTRK-like family, member 4
chr6_+_137387729 0.65 ENSMUST00000203914.2
protein tyrosine phosphatase, receptor type, O
chr7_-_67022520 0.63 ENSMUST00000156690.8
ENSMUST00000107476.8
ENSMUST00000076325.12
ENSMUST00000032776.15
ENSMUST00000133074.2
myocyte enhancer factor 2A
chr11_-_69692542 0.62 ENSMUST00000011285.11
ENSMUST00000102585.2
fibroblast growth factor 11
chr2_-_51039112 0.60 ENSMUST00000154545.2
ENSMUST00000017288.9
Rho family GTPase 3
chr7_+_29821340 0.58 ENSMUST00000098596.11
ENSMUST00000153792.2
zinc finger protein 382
chr13_+_16186410 0.58 ENSMUST00000042603.14
inhibin beta-A
chr10_-_81037878 0.58 ENSMUST00000005069.8
nicotinamide riboside kinase 2
chr4_-_41048124 0.57 ENSMUST00000030136.13
aquaporin 7
chr7_-_30251680 0.57 ENSMUST00000215288.2
ENSMUST00000108165.8
ENSMUST00000153594.3
proline and serine rich 3
chr3_-_95049655 0.57 ENSMUST00000013851.4
tumor necrosis factor, alpha-induced protein 8-like 2
chr15_-_82796308 0.57 ENSMUST00000109510.10
ENSMUST00000048966.7
transcription factor 20
chr14_-_20714634 0.56 ENSMUST00000119483.2
synaptopodin 2-like
chr12_+_52746158 0.56 ENSMUST00000095737.5
A kinase (PRKA) anchor protein 6
chr13_+_83721696 0.55 ENSMUST00000197146.5
ENSMUST00000185052.6
ENSMUST00000195984.5
myocyte enhancer factor 2C
chr6_+_43149074 0.54 ENSMUST00000216179.2
olfactory receptor 13
chr18_-_25886908 0.52 ENSMUST00000115816.3
ENSMUST00000223704.2
CUGBP, Elav-like family member 4
chrM_+_7006 0.52 ENSMUST00000082405.1
mitochondrially encoded cytochrome c oxidase II
chr19_-_60779077 0.51 ENSMUST00000025955.8
eukaryotic translation initiation factor 3, subunit A
chr15_-_80989200 0.50 ENSMUST00000109579.9
myocardin related transcription factor A
chr19_-_31742427 0.50 ENSMUST00000065067.14
protein kinase, cGMP-dependent, type I
chr1_-_74788013 0.48 ENSMUST00000188073.7
protein kinase, AMP-activated, gamma 3 non-catalytic subunit
chr3_+_137849189 0.47 ENSMUST00000040321.13
tRNA methyltransferase 10A
chr2_+_129434834 0.46 ENSMUST00000103203.8
signal-regulatory protein alpha
chr2_+_129434738 0.46 ENSMUST00000153491.8
ENSMUST00000161620.8
ENSMUST00000179001.8
signal-regulatory protein alpha
chr19_-_46315543 0.46 ENSMUST00000223917.2
ENSMUST00000224447.2
ENSMUST00000041391.5
ENSMUST00000096029.12
pleckstrin and Sec7 domain containing
chr8_+_23548541 0.45 ENSMUST00000173248.8
ankyrin 1, erythroid
chr19_+_23881821 0.44 ENSMUST00000237688.2
amyloid beta (A4) precursor protein binding, family A, member 1
chr7_-_81216687 0.44 ENSMUST00000042318.6
fibronectin type III and SPRY domain containing 2
chr2_-_103858632 0.43 ENSMUST00000056170.4
RIKEN cDNA 4931422A03 gene
chr16_-_13977084 0.43 ENSMUST00000090300.6
meiosis regulator and mRNA stability 1
chr3_+_84500854 0.43 ENSMUST00000062623.4
tigger transposable element derived 4
chr13_-_74512111 0.42 ENSMUST00000022064.5
leucine rich repeat containing 14B
chr13_+_102830104 0.41 ENSMUST00000172138.2
CD180 antigen
chr10_+_127256736 0.40 ENSMUST00000064793.13
R3H domain containing 2
chr6_-_142647985 0.40 ENSMUST00000205202.3
ENSMUST00000073173.12
ENSMUST00000111771.8
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr17_+_6047112 0.39 ENSMUST00000115786.8
synaptojanin 2
chr1_+_131671751 0.39 ENSMUST00000049027.10
solute carrier family 26, member 9
chr2_-_77000936 0.38 ENSMUST00000164114.9
ENSMUST00000049544.14
coiled-coil domain containing 141
chr15_+_25940859 0.38 ENSMUST00000226750.2
reticulophagy regulator 1
chr11_+_46126274 0.37 ENSMUST00000060185.3
fibronectin type III domain containing 9
chr6_+_53264255 0.37 ENSMUST00000203528.3
cAMP responsive element binding protein 5
chr2_+_118493713 0.36 ENSMUST00000099557.10
p21 (RAC1) activated kinase 6
chr2_-_151815307 0.36 ENSMUST00000109863.2
family with sequence similarity 110, member A
chr16_+_44913974 0.36 ENSMUST00000099498.10
coiled-coil domain containing 80
chr4_+_135975243 0.36 ENSMUST00000102533.11
ENSMUST00000143942.2
transcription elongation factor A (SII), 3
chr1_+_42734051 0.35 ENSMUST00000239323.2
ENSMUST00000199521.5
ENSMUST00000176807.3
POU domain, class 3, transcription factor 3
predicted gene 20646
chr4_-_126150066 0.34 ENSMUST00000122129.8
ENSMUST00000061143.15
ENSMUST00000106132.3
MAP7 domain containing 1
chr12_+_24701273 0.34 ENSMUST00000020982.7
Kruppel-like factor 11
chr9_-_18675292 0.33 ENSMUST00000216754.3
olfactory receptor 24
chr9_+_99511876 0.33 ENSMUST00000112886.9
DAZ interacting protein 1-like
chr2_-_57014015 0.32 ENSMUST00000112629.8
nuclear receptor subfamily 4, group A, member 2
chr5_-_51711204 0.32 ENSMUST00000196968.5
peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
chr15_+_25940931 0.32 ENSMUST00000110438.3
reticulophagy regulator 1
chr1_+_16758731 0.31 ENSMUST00000190366.2
lymphocyte antigen 96
chr13_+_83672389 0.31 ENSMUST00000200394.5
myocyte enhancer factor 2C
chr11_+_95603494 0.31 ENSMUST00000107717.8
zinc finger protein 652
chr16_+_13176238 0.30 ENSMUST00000149359.2
myocardin related transcription factor B
chr6_+_126992549 0.29 ENSMUST00000000187.7
fibroblast growth factor 6
chr14_-_36641470 0.28 ENSMUST00000182042.2
coiled-coil serine rich 2
chr10_+_127256993 0.28 ENSMUST00000170336.8
R3H domain containing 2
chr1_+_132996237 0.28 ENSMUST00000239467.2
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta
chr2_+_102488985 0.27 ENSMUST00000080210.10
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr9_-_70048766 0.27 ENSMUST00000034749.16
family with sequence similarity 81, member A
chr19_-_40365318 0.26 ENSMUST00000239304.2
sorbin and SH3 domain containing 1
chr1_-_152642032 0.26 ENSMUST00000111859.8
ral guanine nucleotide dissociation stimulator,-like 1
chr7_+_142052569 0.25 ENSMUST00000078497.15
ENSMUST00000105953.10
ENSMUST00000179658.8
ENSMUST00000105954.10
ENSMUST00000105952.10
ENSMUST00000105955.8
ENSMUST00000074187.13
ENSMUST00000169299.9
ENSMUST00000105957.10
ENSMUST00000180152.8
ENSMUST00000105950.11
ENSMUST00000105958.10
ENSMUST00000105949.8
troponin T3, skeletal, fast
chr16_-_36810810 0.25 ENSMUST00000075869.13
F-box protein 40
chr11_-_69260203 0.25 ENSMUST00000092971.13
ENSMUST00000108661.8
chromodomain helicase DNA binding protein 3
chr17_+_50816296 0.25 ENSMUST00000043938.8
phospholipase C-like 2
chr6_+_134958681 0.25 ENSMUST00000167323.3
apolipoprotein L domain containing 1
chr1_-_135513443 0.24 ENSMUST00000067414.13
neuron navigator 1
chr5_+_64316771 0.24 ENSMUST00000043893.13
TBC1 domain family, member 1
chr11_+_73051228 0.24 ENSMUST00000006104.10
ENSMUST00000135202.8
ENSMUST00000136894.3
purinergic receptor P2X, ligand-gated ion channel, 5
chr19_+_11352862 0.23 ENSMUST00000188995.2
membrane-spanning 4-domains, subfamily A, member 4A
chr18_+_61096597 0.23 ENSMUST00000115295.9
calcium/calmodulin-dependent protein kinase II alpha
chr15_-_66432938 0.22 ENSMUST00000048372.7
transmembrane protein 71
chr19_+_3758285 0.22 ENSMUST00000237320.2
ENSMUST00000039048.2
ENSMUST00000235295.2
ENSMUST00000237955.2
ENSMUST00000235837.2
RIKEN cDNA 1810055G02 gene
chr4_+_11485945 0.22 ENSMUST00000055372.14
ENSMUST00000059914.13
vir like m6A methyltransferase associated
chr15_+_25940781 0.22 ENSMUST00000227275.2
reticulophagy regulator 1
chr17_+_71326510 0.22 ENSMUST00000073211.13
ENSMUST00000024847.14
myomesin 1
chr7_+_28510350 0.22 ENSMUST00000174477.8
heterogeneous nuclear ribonucleoprotein L
chr3_-_113166153 0.21 ENSMUST00000098673.5
amylase 2a5
chr18_-_47501897 0.21 ENSMUST00000019791.14
ENSMUST00000115449.9
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr1_-_186438177 0.21 ENSMUST00000045288.14
transforming growth factor, beta 2
chr7_-_115630282 0.20 ENSMUST00000206034.2
ENSMUST00000106612.8
SRY (sex determining region Y)-box 6
chr4_+_156300325 0.19 ENSMUST00000105572.3
PPARGC1 and ESRR induced regulator, muscle 1
chr6_+_121277186 0.19 ENSMUST00000064580.14
solute carrier family 6 (neurotransmitter transporter, GABA), member 13
chr16_-_90866032 0.19 ENSMUST00000035689.8
ENSMUST00000114076.2
RIKEN cDNA 4932438H23 gene
chr11_+_67090878 0.18 ENSMUST00000124516.8
ENSMUST00000018637.15
ENSMUST00000129018.8
myosin, heavy polypeptide 1, skeletal muscle, adult
chr16_+_43184191 0.18 ENSMUST00000156367.8
zinc finger and BTB domain containing 20
chr7_-_30755007 0.18 ENSMUST00000206474.2
ENSMUST00000205807.2
ENSMUST00000039909.13
ENSMUST00000206305.2
ENSMUST00000205439.2
FXYD domain-containing ion transport regulator 1
chr11_-_69838971 0.17 ENSMUST00000179298.3
ENSMUST00000018710.13
ENSMUST00000135437.3
ENSMUST00000141837.9
ENSMUST00000142500.8
solute carrier family 2 (facilitated glucose transporter), member 4
chr2_-_92222979 0.17 ENSMUST00000111279.9
mitogen-activated protein kinase 8 interacting protein 1
chr4_+_133280680 0.16 ENSMUST00000042706.3
nuclear receptor subfamily 0, group B, member 2
chr10_+_22520910 0.16 ENSMUST00000042261.5
solute carrier family 2 (facilitated glucose transporter), member 12
chrX_+_6489313 0.16 ENSMUST00000089520.3
shroom family member 4
chr19_+_21249636 0.16 ENSMUST00000237651.2
zinc finger, AN1-type domain 5
chr18_+_69652751 0.16 ENSMUST00000200966.4
transcription factor 4
chr6_-_116050081 0.15 ENSMUST00000173548.3
transmembrane and coiled coil domains 1
chr13_-_103233323 0.15 ENSMUST00000166336.9
ENSMUST00000239261.2
ENSMUST00000194446.7
microtubule associated serine/threonine kinase family member 4
chr1_+_75351914 0.15 ENSMUST00000087122.12
SPEG complex locus
chr4_+_46039202 0.15 ENSMUST00000156200.8
tropomodulin 1
chr5_+_122239007 0.15 ENSMUST00000014080.13
ENSMUST00000111750.8
myosin, light polypeptide 2, regulatory, cardiac, slow
chr7_-_101486983 0.15 ENSMUST00000185929.2
ENSMUST00000165052.8
inositol polyphosphate phosphatase-like 1
chr12_-_109566764 0.15 ENSMUST00000149046.4
retrotransposon Gaglike 1
chr14_-_66518399 0.14 ENSMUST00000111121.2
ENSMUST00000022622.14
ENSMUST00000089250.9
PTK2 protein tyrosine kinase 2 beta
chr10_+_88036947 0.13 ENSMUST00000020248.16
ENSMUST00000182183.8
ENSMUST00000171151.9
ENSMUST00000182619.2
WASH complex subunit 3
chr8_-_41469786 0.13 ENSMUST00000117735.8
mitochondrial tumor suppressor 1
chrX_-_58613428 0.12 ENSMUST00000119833.8
ENSMUST00000131319.8
fibroblast growth factor 13
chrX_-_161747552 0.12 ENSMUST00000038769.3
S100 calcium binding protein G
chr18_-_79152504 0.12 ENSMUST00000025430.11
SET binding protein 1
chr17_+_85335775 0.11 ENSMUST00000024944.9
solute carrier family 3, member 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Mef2d_Mef2a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.7 GO:0007066 female meiosis sister chromatid cohesion(GO:0007066)
0.6 2.5 GO:0001928 regulation of exocyst assembly(GO:0001928)
0.5 3.6 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.4 1.1 GO:1903210 glomerular visceral epithelial cell apoptotic process(GO:1903210) regulation of glomerular visceral epithelial cell apoptotic process(GO:1904633) positive regulation of glomerular visceral epithelial cell apoptotic process(GO:1904635) positive regulation of progesterone biosynthetic process(GO:2000184)
0.3 3.4 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.3 1.4 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.3 1.6 GO:1904048 negative regulation of synaptic vesicle recycling(GO:1903422) regulation of spontaneous neurotransmitter secretion(GO:1904048)
0.2 1.7 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.2 0.7 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.2 0.7 GO:0014737 positive regulation of muscle atrophy(GO:0014737)
0.2 0.9 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.2 1.0 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
0.2 2.5 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.2 2.0 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.2 0.9 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.2 2.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 1.0 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.1 0.7 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.1 0.5 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.1 0.6 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.1 1.3 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 0.4 GO:0072023 ascending thin limb development(GO:0072021) thick ascending limb development(GO:0072023) metanephric ascending thin limb development(GO:0072218) metanephric thick ascending limb development(GO:0072233)
0.1 0.8 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1 1.0 GO:0061709 reticulophagy(GO:0061709)
0.1 1.8 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 0.7 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.1 0.6 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.1 1.3 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.1 0.5 GO:2000224 regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608) regulation of testosterone biosynthetic process(GO:2000224)
0.1 0.4 GO:0060279 positive regulation of ovulation(GO:0060279)
0.1 1.2 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.1 0.4 GO:0015793 glycerol transport(GO:0015793) renal water absorption(GO:0070295)
0.1 0.2 GO:0051795 positive regulation of catagen(GO:0051795) positive regulation of activation-induced cell death of T cells(GO:0070237) negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905006)
0.1 0.1 GO:0007172 signal complex assembly(GO:0007172)
0.1 0.9 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 0.3 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 1.0 GO:0099628 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.1 0.2 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.1 1.1 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.3 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.0 0.2 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.0 0.1 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.0 0.3 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:0035523 protein K29-linked deubiquitination(GO:0035523)
0.0 0.7 GO:0002024 diet induced thermogenesis(GO:0002024)
0.0 3.1 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.0 3.7 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.9 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 2.2 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.7 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 1.7 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 1.5 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.4 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 2.1 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.2 GO:1903797 positive regulation of inorganic anion transmembrane transport(GO:1903797)
0.0 0.4 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.0 0.6 GO:0019363 pyridine nucleotide biosynthetic process(GO:0019363)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.7 GO:0090382 phagosome maturation(GO:0090382)
0.0 0.2 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0 0.4 GO:0008272 sulfate transport(GO:0008272)
0.0 0.2 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.0 0.8 GO:0070328 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.0 0.1 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 0.3 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.1 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.0 0.5 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.0 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.0 0.5 GO:0030488 tRNA methylation(GO:0030488)
0.0 1.0 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.1 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 1.8 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 3.5 GO:0007411 axon guidance(GO:0007411)
0.0 0.3 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.0 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.0 0.2 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.5 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.7 GO:0000802 transverse filament(GO:0000802) nuclear meiotic cohesin complex(GO:0034991)
0.4 1.1 GO:1990844 subsarcolemmal mitochondrion(GO:1990843) interfibrillar mitochondrion(GO:1990844)
0.2 1.0 GO:0099573 glutamatergic postsynaptic density(GO:0099573)
0.2 1.0 GO:0044316 cone cell pedicle(GO:0044316)
0.2 1.4 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.4 GO:0043512 inhibin A complex(GO:0043512)
0.1 1.0 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 0.3 GO:0043614 multi-eIF complex(GO:0043614)
0.1 1.6 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 0.7 GO:1990923 PET complex(GO:1990923)
0.1 0.4 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1 2.2 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.2 GO:0044302 dentate gyrus mossy fiber(GO:0044302)
0.0 0.2 GO:0042642 actomyosin, myosin complex part(GO:0042642)
0.0 0.3 GO:0005899 insulin receptor complex(GO:0005899)
0.0 1.1 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.9 GO:0010369 chromocenter(GO:0010369)
0.0 0.6 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 1.0 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.4 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.5 GO:0090543 Flemming body(GO:0090543)
0.0 0.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0036396 MIS complex(GO:0036396)
0.0 5.0 GO:0001650 fibrillar center(GO:0001650)
0.0 0.5 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 1.4 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.7 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 2.8 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 1.1 GO:0030118 clathrin coat(GO:0030118)
0.0 1.0 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.3 GO:0032982 myosin filament(GO:0032982)
0.0 1.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.3 GO:0070971 endoplasmic reticulum exit site(GO:0070971)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.7 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.6 1.7 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.3 1.0 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.3 1.9 GO:0004111 creatine kinase activity(GO:0004111)
0.2 1.4 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.2 0.6 GO:0061769 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
0.2 1.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.2 1.2 GO:0001515 opioid peptide activity(GO:0001515)
0.1 3.3 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 1.7 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 1.0 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.6 GO:0015254 glycerol channel activity(GO:0015254)
0.1 0.7 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 4.0 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 2.5 GO:0030275 LRR domain binding(GO:0030275)
0.1 0.5 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 0.8 GO:0050786 RAGE receptor binding(GO:0050786)
0.1 1.3 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 0.5 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 1.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 1.0 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 0.9 GO:0051525 NFAT protein binding(GO:0051525)
0.1 2.4 GO:0030506 ankyrin binding(GO:0030506)
0.1 1.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.4 GO:0034711 inhibin binding(GO:0034711)
0.0 0.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 1.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.2 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.0 0.2 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 1.4 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.9 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.2 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.5 GO:0046030 inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol trisphosphate phosphatase activity(GO:0046030)
0.0 0.6 GO:0043495 protein anchor(GO:0043495)
0.0 1.7 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.2 GO:0004556 alpha-amylase activity(GO:0004556)
0.0 0.2 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.2 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 1.8 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.3 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 1.3 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.4 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 1.0 GO:0030552 cAMP binding(GO:0030552)
0.0 0.1 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.5 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 1.0 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.7 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 2.5 GO:0008083 growth factor activity(GO:0008083)
0.0 2.4 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.2 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.6 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.4 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.0 GO:0004802 transketolase activity(GO:0004802)
0.0 0.2 GO:0050811 GABA receptor binding(GO:0050811)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 PID FGF PATHWAY FGF signaling pathway
0.1 3.3 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 2.4 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 2.3 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 1.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.6 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 1.2 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 2.4 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.2 PID FOXO PATHWAY FoxO family signaling
0.0 0.9 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.2 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.9 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 1.0 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.7 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.1 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.2 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.1 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.4 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.2 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 1.4 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 1.6 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 3.3 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.1 1.1 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 2.3 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 2.7 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 3.5 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 1.7 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 1.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 1.9 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 1.5 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.4 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.5 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 1.0 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.8 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.3 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.9 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)