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avrg: GFI1 WT vs 36n/n vs KD

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Results for Msx3

Z-value: 0.55

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Transcription factors associated with Msx3

Gene Symbol Gene ID Gene Info
Msx3
ENSMUSG00000025469.11 msh homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Msx3mm39_v1_chr7_-_139628991_1396290070.573.1e-01Click!

Activity profile of Msx3 motif

Sorted Z-values of Msx3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chrX_+_16485937 0.65 ENSMUST00000026013.6
Maoa
monoamine oxidase A
chr19_+_13208692 0.47 ENSMUST00000207246.4
Olfr1463
olfactory receptor 1463
chrX_-_48980360 0.38 ENSMUST00000217355.3
Olfr1322
olfactory receptor 1322
chr7_+_140181182 0.36 ENSMUST00000214180.2
ENSMUST00000211771.2
Olfr46
olfactory receptor 46
chr3_-_129834788 0.34 ENSMUST00000168644.3
Sec24b
Sec24 related gene family, member B (S. cerevisiae)
chr7_+_3648264 0.33 ENSMUST00000206287.2
ENSMUST00000038913.16
Cnot3
CCR4-NOT transcription complex, subunit 3
chr2_-_111820618 0.32 ENSMUST00000216948.2
ENSMUST00000214935.2
ENSMUST00000217452.2
ENSMUST00000215045.2
Olfr1309
olfactory receptor 1309
chr13_+_23191826 0.29 ENSMUST00000228758.2
ENSMUST00000228031.2
ENSMUST00000227573.2
Vmn1r213
vomeronasal 1 receptor 213
chr2_-_111843053 0.29 ENSMUST00000213559.3
Olfr1310
olfactory receptor 1310
chr7_-_107633196 0.28 ENSMUST00000210173.3
Olfr478
olfactory receptor 478
chr17_-_37523969 0.27 ENSMUST00000060728.7
ENSMUST00000216318.2
Olfr95
olfactory receptor 95
chr10_-_75946790 0.24 ENSMUST00000120757.2
Slc5a4b
solute carrier family 5 (neutral amino acid transporters, system A), member 4b
chr2_+_96148418 0.20 ENSMUST00000135431.8
ENSMUST00000162807.9
Lrrc4c
leucine rich repeat containing 4C
chr13_+_22508759 0.20 ENSMUST00000226225.2
ENSMUST00000227017.2
Vmn1r197
vomeronasal 1 receptor 197
chr13_+_23398297 0.19 ENSMUST00000236177.2
Vmn1r221
vomeronasal 1 receptor 221
chr2_+_87696836 0.18 ENSMUST00000213308.3
Olfr1152
olfactory receptor 1152
chr11_-_73382303 0.17 ENSMUST00000119863.2
ENSMUST00000215358.2
ENSMUST00000214623.2
Olfr381
olfactory receptor 381
chr16_+_11224481 0.16 ENSMUST00000122168.8
Snx29
sorting nexin 29
chr3_+_94745009 0.15 ENSMUST00000107266.8
ENSMUST00000042402.12
ENSMUST00000107269.2
Pogz
pogo transposable element with ZNF domain
chr2_-_45007407 0.14 ENSMUST00000176438.9
Zeb2
zinc finger E-box binding homeobox 2
chr2_-_32976378 0.14 ENSMUST00000049618.9
Garnl3
GTPase activating RANGAP domain-like 3
chr3_+_66892979 0.14 ENSMUST00000162362.8
ENSMUST00000065074.14
ENSMUST00000065047.13
Rsrc1
arginine/serine-rich coiled-coil 1
chr9_+_38516398 0.13 ENSMUST00000217057.2
Olfr914
olfactory receptor 914
chr17_+_30940015 0.12 ENSMUST00000236948.2
Dnah8
dynein, axonemal, heavy chain 8
chr5_+_104350475 0.11 ENSMUST00000066708.7
Dmp1
dentin matrix protein 1
chr7_-_12829100 0.11 ENSMUST00000209822.3
ENSMUST00000235753.2
Vmn1r85
vomeronasal 1 receptor 85
chrX_-_142716200 0.11 ENSMUST00000112851.8
ENSMUST00000112856.3
ENSMUST00000033642.10
Dcx
doublecortin
chr11_-_99134885 0.10 ENSMUST00000103132.10
ENSMUST00000038214.7
Krt222
keratin 222
chr6_+_68279392 0.10 ENSMUST00000103322.3
Igkv2-109
immunoglobulin kappa variable 2-109
chr3_+_94744844 0.10 ENSMUST00000107270.9
Pogz
pogo transposable element with ZNF domain
chr1_+_104696235 0.10 ENSMUST00000062528.9
Cdh20
cadherin 20
chr10_+_85763545 0.09 ENSMUST00000170396.3
Ascl4
achaete-scute family bHLH transcription factor 4
chr2_-_32977182 0.09 ENSMUST00000102810.10
Garnl3
GTPase activating RANGAP domain-like 3
chr2_+_88348895 0.09 ENSMUST00000216978.2
ENSMUST00000215912.2
Olfr1186
olfactory receptor 1186
chr13_+_22268610 0.09 ENSMUST00000228243.2
ENSMUST00000226680.2
Vmn1r188
vomeronasal 1 receptor 188
chr5_+_88731386 0.09 ENSMUST00000031229.11
Rufy3
RUN and FYVE domain containing 3
chr14_+_60615128 0.08 ENSMUST00000022561.9
Amer2
APC membrane recruitment 2
chr3_-_97329336 0.08 ENSMUST00000199297.4
Olfr1402
olfactory receptor 1402
chr5_+_14564932 0.08 ENSMUST00000182407.8
ENSMUST00000030691.17
Pclo
piccolo (presynaptic cytomatrix protein)
chr18_+_4993795 0.08 ENSMUST00000153016.8
Svil
supervillin
chr12_+_102094977 0.07 ENSMUST00000159329.8
Slc24a4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr8_+_72973560 0.07 ENSMUST00000003123.10
Fam32a
family with sequence similarity 32, member A
chr2_-_89671899 0.07 ENSMUST00000213833.2
Olfr1256
olfactory receptor 1256
chr10_+_39488930 0.07 ENSMUST00000019987.7
Traf3ip2
TRAF3 interacting protein 2
chr10_+_88214989 0.07 ENSMUST00000127615.8
Gnptab
N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
chr3_+_41697046 0.06 ENSMUST00000120167.8
ENSMUST00000108065.9
ENSMUST00000146165.8
ENSMUST00000192193.6
ENSMUST00000119572.8
ENSMUST00000026867.14
ENSMUST00000026868.13
D3Ertd751e
DNA segment, Chr 3, ERATO Doi 751, expressed
chrX_+_106299484 0.06 ENSMUST00000101294.9
ENSMUST00000118820.8
ENSMUST00000120971.8
Gpr174
G protein-coupled receptor 174
chr12_-_114443071 0.06 ENSMUST00000103492.2
Ighv10-1
immunoglobulin heavy variable 10-1
chr10_+_88215079 0.06 ENSMUST00000130301.8
ENSMUST00000020251.10
Gnptab
N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
chr4_-_43710231 0.06 ENSMUST00000217544.2
ENSMUST00000107862.3
Olfr71
olfactory receptor 71
chr4_+_134658209 0.05 ENSMUST00000030622.3
Syf2
SYF2 homolog, RNA splicing factor (S. cerevisiae)
chrX_+_100492684 0.05 ENSMUST00000033674.6
Itgb1bp2
integrin beta 1 binding protein 2
chr7_+_84562283 0.04 ENSMUST00000216367.2
ENSMUST00000214501.3
Olfr290
olfactory receptor 290
chr17_-_24746804 0.04 ENSMUST00000176353.8
ENSMUST00000176237.8
Traf7
TNF receptor-associated factor 7
chr19_+_12257218 0.04 ENSMUST00000207186.4
ENSMUST00000207915.2
Olfr1434
olfactory receptor 1434
chr17_-_24746911 0.04 ENSMUST00000176652.8
Traf7
TNF receptor-associated factor 7
chr14_+_122272069 0.03 ENSMUST00000045976.7
Timm8a2
translocase of inner mitochondrial membrane 8A2
chr1_-_97055931 0.03 ENSMUST00000027569.14
Slco6c1
solute carrier organic anion transporter family, member 6c1
chr3_-_41696906 0.03 ENSMUST00000026866.15
Sclt1
sodium channel and clathrin linker 1
chr11_+_6366259 0.03 ENSMUST00000213200.2
Ppia
peptidylprolyl isomerase A
chr15_+_82136598 0.02 ENSMUST00000136948.3
1500009C09Rik
RIKEN cDNA 1500009C09 gene
chr2_+_121787131 0.02 ENSMUST00000110574.8
Ctdspl2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr13_-_23041731 0.02 ENSMUST00000228645.2
Vmn1r211
vomeronasal 1 receptor 211
chr4_-_43840201 0.02 ENSMUST00000214281.2
Olfr157
olfactory receptor 157
chr9_+_100479732 0.02 ENSMUST00000124487.8
Stag1
stromal antigen 1
chr17_+_49922129 0.01 ENSMUST00000162854.2
Kif6
kinesin family member 6
chr13_+_22563988 0.00 ENSMUST00000227685.2
ENSMUST00000227689.2
ENSMUST00000227846.2
Vmn1r199
vomeronasal 1 receptor 199
chr4_+_102112189 0.00 ENSMUST00000106908.9
Pde4b
phosphodiesterase 4B, cAMP specific
chr7_-_98790275 0.00 ENSMUST00000037968.10
Uvrag
UV radiation resistance associated gene
chr12_-_113649535 0.00 ENSMUST00000103449.4
ENSMUST00000195707.3
Ighv2-5
immunoglobulin heavy variable 2-5
chr9_+_72714156 0.00 ENSMUST00000055535.9
Prtg
protogenin
chrM_+_9870 0.00 ENSMUST00000084013.1
mt-Nd4l
mitochondrially encoded NADH dehydrogenase 4L
chr9_+_96140781 0.00 ENSMUST00000190104.7
ENSMUST00000179416.8
ENSMUST00000189606.7
Tfdp2
transcription factor Dp 2
chr6_+_48604157 0.00 ENSMUST00000203088.3
ENSMUST00000204958.2
AI854703
expressed sequence AI854703
chr5_-_140986312 0.00 ENSMUST00000085786.7
Card11
caspase recruitment domain family, member 11

Network of associatons between targets according to the STRING database.

First level regulatory network of Msx3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0042420 dopamine catabolic process(GO:0042420)
0.1 0.3 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.1 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.0 0.1 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.0 0.1 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.0 0.1 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.2 GO:1904659 glucose transmembrane transport(GO:1904659)
0.0 0.2 GO:0051382 kinetochore assembly(GO:0051382)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.1 GO:0044317 rod spherule(GO:0044317)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0036157 outer dynein arm(GO:0036157)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.2 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.3 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC