Project

avrg: GFI1 WT vs 36n/n vs KD

Navigation
Downloads

Results for Mtf1

Z-value: 0.65

Motif logo

Transcription factors associated with Mtf1

Gene Symbol Gene ID Gene Info
ENSMUSG00000028890.14 metal response element binding transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Mtf1mm39_v1_chr4_+_124696336_124696381-0.553.4e-01Click!

Activity profile of Mtf1 motif

Sorted Z-values of Mtf1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_94905710 0.43 ENSMUST00000034215.8
ENSMUST00000212291.2
ENSMUST00000211807.2
metallothionein 1
chr6_+_18848600 0.38 ENSMUST00000201141.3
LSM8 homolog, U6 small nuclear RNA associated
chr15_+_101184488 0.35 ENSMUST00000229525.2
ENSMUST00000230525.2
autophagy related 101
chr16_+_22676589 0.35 ENSMUST00000004574.14
ENSMUST00000178320.2
ENSMUST00000166487.10
DnaJ heat shock protein family (Hsp40) member B11
chr1_+_127132712 0.34 ENSMUST00000038361.11
mannoside acetylglucosaminyltransferase 5
chr11_+_98938137 0.32 ENSMUST00000140772.2
insulin-like growth factor binding protein 4
chr6_+_18848570 0.27 ENSMUST00000056398.11
LSM8 homolog, U6 small nuclear RNA associated
chr12_-_36206780 0.25 ENSMUST00000223382.2
ENSMUST00000020856.6
basic leucine zipper and W2 domains 2
chr12_-_36206626 0.25 ENSMUST00000220828.2
basic leucine zipper and W2 domains 2
chr12_-_36206750 0.25 ENSMUST00000221388.2
basic leucine zipper and W2 domains 2
chr18_+_11972277 0.24 ENSMUST00000171109.9
ENSMUST00000046948.10
CDK5 and Abl enzyme substrate 1
chr5_-_34794185 0.22 ENSMUST00000149657.5
major facilitator superfamily domain containing 10
chr1_-_169359015 0.20 ENSMUST00000111368.8
NUF2, NDC80 kinetochore complex component
chr4_+_133302039 0.19 ENSMUST00000030662.3
G patch domain containing 3
chr9_+_109662063 0.18 ENSMUST00000197627.5
ENSMUST00000200468.2
NME/NM23 nucleoside diphosphate kinase 6
chr4_+_138700195 0.18 ENSMUST00000123636.8
ENSMUST00000043042.10
ENSMUST00000050949.9
transmembrane and coiled-coil domains 4
chr13_-_46118433 0.17 ENSMUST00000167708.4
ENSMUST00000091628.11
ENSMUST00000180110.9
ataxin 1
chr8_-_106937555 0.17 ENSMUST00000035925.7
solute carrier family 7, member 6 opposite strand
chr5_-_34794451 0.15 ENSMUST00000124668.2
ENSMUST00000001109.11
ENSMUST00000155577.8
ENSMUST00000114329.8
major facilitator superfamily domain containing 10
chrX_+_7446721 0.15 ENSMUST00000115738.8
forkhead box P3
chr2_+_118943274 0.15 ENSMUST00000140939.8
ENSMUST00000028795.10
RAD51 recombinase
chr19_-_41252370 0.15 ENSMUST00000237871.2
ENSMUST00000025989.10
transmembrane 9 superfamily member 3
chr19_-_4889314 0.14 ENSMUST00000235245.2
ENSMUST00000037246.7
copper chaperone for superoxide dismutase
chr3_+_107803225 0.14 ENSMUST00000172247.8
ENSMUST00000167387.8
glutathione S-transferase, mu 5
chr6_-_83752749 0.13 ENSMUST00000014892.8
testis expressed gene 261
chr3_+_107803563 0.13 ENSMUST00000169365.2
glutathione S-transferase, mu 5
chr1_-_169358912 0.13 ENSMUST00000192248.2
ENSMUST00000028000.13
NUF2, NDC80 kinetochore complex component
chr2_-_119617985 0.13 ENSMUST00000110793.8
ENSMUST00000099529.9
ENSMUST00000048493.12
RNA polymerase II associated protein 1
chr14_+_59438658 0.13 ENSMUST00000173547.8
ENSMUST00000043227.13
ENSMUST00000022551.14
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
chr17_-_71833752 0.12 ENSMUST00000232863.2
ENSMUST00000024851.10
NDC80 kinetochore complex component
chr10_+_20828446 0.12 ENSMUST00000105525.12
Abelson helper integration site 1
chr5_+_31026967 0.12 ENSMUST00000114716.4
transmembrane protein 214
chr8_+_106937568 0.12 ENSMUST00000071592.12
protein arginine N-methyltransferase 7
chr7_+_132212349 0.12 ENSMUST00000033241.6
ENSMUST00000106170.8
phospholysine phosphohistidine inorganic pyrophosphate phosphatase
chr6_-_39095144 0.11 ENSMUST00000038398.7
poly (ADP-ribose) polymerase family, member 12
chr18_-_77652820 0.11 ENSMUST00000026494.14
ENSMUST00000182024.2
ring finger protein 165
chr19_-_4889284 0.11 ENSMUST00000236451.2
ENSMUST00000236178.2
copper chaperone for superoxide dismutase
chr1_+_135656885 0.11 ENSMUST00000027677.8
cysteine and glycine-rich protein 1
chr16_+_56942050 0.11 ENSMUST00000166897.3
translocase of outer mitochondrial membrane 70A
chr7_+_43256593 0.10 ENSMUST00000120935.2
ENSMUST00000127765.8
ENSMUST00000032661.14
zinc finger protein 819
chr6_-_87827993 0.10 ENSMUST00000204890.3
ENSMUST00000113617.3
ENSMUST00000113619.8
ENSMUST00000204653.3
ENSMUST00000032138.15
cellular nucleic acid binding protein
chr5_+_57875309 0.10 ENSMUST00000191837.6
ENSMUST00000068110.10
protocadherin 7
chr6_-_56900917 0.10 ENSMUST00000031793.8
5'-nucleotidase, cytosolic III
chr7_-_15656285 0.10 ENSMUST00000044355.11
selenoprotein W
chr11_+_4845328 0.09 ENSMUST00000038237.8
THO complex 5
chr17_-_56933872 0.09 ENSMUST00000047226.10
lon peptidase 1, mitochondrial
chr11_+_50022167 0.09 ENSMUST00000093138.13
ENSMUST00000101270.5
TBC1 domain family, member 9B
chr11_+_4845314 0.09 ENSMUST00000101615.9
THO complex 5
chr10_+_77442405 0.09 ENSMUST00000099538.6
small ubiquitin-like modifier 3
chr8_+_94899292 0.08 ENSMUST00000034214.8
ENSMUST00000212806.2
metallothionein 2
chr15_-_83033508 0.08 ENSMUST00000100375.11
polymerase (DNA-directed), delta interacting protein 3
chr16_-_18165876 0.08 ENSMUST00000125287.9
transport and golgi organization 2
chr5_-_34794546 0.08 ENSMUST00000114331.10
major facilitator superfamily domain containing 10
chrX_-_8072714 0.07 ENSMUST00000089403.10
ENSMUST00000077595.12
ENSMUST00000089402.10
ENSMUST00000082320.12
porcupine O-acyltransferase
chr15_-_83033559 0.07 ENSMUST00000058793.14
polymerase (DNA-directed), delta interacting protein 3
chr15_+_81686622 0.06 ENSMUST00000109553.10
thyrotroph embryonic factor
chr8_+_124100588 0.06 ENSMUST00000211932.2
ENSMUST00000212569.2
transcription factor 25 (basic helix-loop-helix)
chr1_-_157240138 0.06 ENSMUST00000078308.13
RAS protein activator like 2
chr9_-_14292269 0.06 ENSMUST00000214236.2
endonuclease domain containing 1
chr14_-_63781381 0.06 ENSMUST00000058679.7
myotubularin related protein 9
chr10_-_80837173 0.06 ENSMUST00000099462.8
ENSMUST00000118233.8
guanine nucleotide binding protein (G protein), gamma 7
chr3_-_121325887 0.05 ENSMUST00000039197.9
solute carrier family 44, member 3
chr13_+_24118417 0.05 ENSMUST00000072391.2
H2A clustered histone 1
chr16_+_38405718 0.05 ENSMUST00000165631.2
transmembrane protein 39a
chr2_-_130506484 0.05 ENSMUST00000089559.11
DDRGK domain containing 1
chr14_+_59438879 0.04 ENSMUST00000140136.9
ENSMUST00000142326.2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
chr5_+_121798932 0.04 ENSMUST00000111765.8
BRCA1 associated protein
chr11_+_4207557 0.04 ENSMUST00000066283.12
leukemia inhibitory factor
chr8_+_13209141 0.04 ENSMUST00000033824.8
lysosomal-associated membrane protein 1
chr8_+_124100492 0.04 ENSMUST00000212571.2
ENSMUST00000212470.2
ENSMUST00000108840.4
ENSMUST00000057934.10
transcription factor 25 (basic helix-loop-helix)
chr16_-_22676264 0.03 ENSMUST00000232075.2
ENSMUST00000004576.8
TBCC domain containing 1
chr19_-_4665509 0.03 ENSMUST00000053597.3
leucine rich repeat and fibronectin type III domain containing 4
chr7_-_46782448 0.03 ENSMUST00000033142.13
protein tyrosine phosphatase, non-receptor type 5
chr7_-_119393182 0.03 ENSMUST00000106523.8
ENSMUST00000063902.14
ENSMUST00000150844.3
exoribonuclease 2
chr3_+_107803137 0.03 ENSMUST00000004134.11
glutathione S-transferase, mu 5
chr4_+_134224308 0.03 ENSMUST00000095074.4
progestin and adipoQ receptor family member VII
chr9_+_108368032 0.03 ENSMUST00000166103.9
ENSMUST00000085044.14
ENSMUST00000193678.6
ENSMUST00000178075.8
ubiquitin specific peptidase 19
chr19_-_4665668 0.03 ENSMUST00000113822.3
leucine rich repeat and fibronectin type III domain containing 4
chr1_+_66426127 0.02 ENSMUST00000145419.8
microtubule-associated protein 2
chr3_+_104688363 0.02 ENSMUST00000002298.7
protein phosphatase 1J
chr1_+_131794962 0.02 ENSMUST00000112386.8
ENSMUST00000027693.8
RAB29, member RAS oncogene family
chr7_+_119393312 0.02 ENSMUST00000084644.3
RNA exonuclease 5
chr6_-_30680502 0.02 ENSMUST00000133373.8
centrosomal protein 41
chr18_-_9450097 0.02 ENSMUST00000053917.6
cyclin Y
chr15_+_100366886 0.02 ENSMUST00000037001.10
ENSMUST00000230294.2
LETM1 domain containing 1
chr15_-_93417380 0.01 ENSMUST00000109255.3
prickle planar cell polarity protein 1
chr14_+_30673435 0.01 ENSMUST00000226833.2
NIMA (never in mitosis gene a)-related expressed kinase 4
chr15_+_100366966 0.01 ENSMUST00000229648.2
LETM1 domain containing 1
chr2_-_91067212 0.01 ENSMUST00000111352.8
damage specific DNA binding protein 2
chr5_-_140986312 0.01 ENSMUST00000085786.7
caspase recruitment domain family, member 11
chr8_+_93553901 0.01 ENSMUST00000034187.9
matrix metallopeptidase 2
chr10_+_29023201 0.01 ENSMUST00000213243.2
SOGA family member 3
chr1_+_167445815 0.01 ENSMUST00000111380.2
retinoid X receptor gamma
chr10_+_78749005 0.01 ENSMUST00000204587.4
ENSMUST00000217073.3
olfactory receptor 1354
chr7_+_119393210 0.01 ENSMUST00000033218.15
ENSMUST00000106520.9
RNA exonuclease 5
chr6_-_83654789 0.01 ENSMUST00000037882.8
CD207 antigen
chr11_+_63023395 0.01 ENSMUST00000108701.8
peripheral myelin protein 22
chr11_+_63023893 0.01 ENSMUST00000108700.2
peripheral myelin protein 22
chr1_+_75376714 0.00 ENSMUST00000113589.8
SPEG complex locus
chr6_-_126717590 0.00 ENSMUST00000185333.2
potassium voltage-gated channel, shaker-related, subfamily, member 6
chr6_-_126717114 0.00 ENSMUST00000112242.2
potassium voltage-gated channel, shaker-related, subfamily, member 6
chrX_-_78715030 0.00 ENSMUST00000052283.7
MAGE family member B16
chr18_-_9449947 0.00 ENSMUST00000234102.2
cyclin Y
chr4_-_126057263 0.00 ENSMUST00000097891.4
SH3 domain containing 21
chr10_+_51553852 0.00 ENSMUST00000122922.10
ENSMUST00000219364.2
regulatory factor X, 6
chr17_+_71980249 0.00 ENSMUST00000097284.10
TOG array regulator of axonemal microtubules 2
chr3_+_55047453 0.00 ENSMUST00000118963.9
ENSMUST00000061099.14
ENSMUST00000153009.8
coiled-coil domain containing 169

Network of associatons between targets according to the STRING database.

First level regulatory network of Mtf1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0015904 tetracycline transport(GO:0015904)
0.1 0.5 GO:1990169 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.1 0.2 GO:0002658 positive regulation of tolerance induction dependent upon immune response(GO:0002654) regulation of peripheral tolerance induction(GO:0002658) positive regulation of peripheral tolerance induction(GO:0002660) regulation of peripheral T cell tolerance induction(GO:0002849) positive regulation of peripheral T cell tolerance induction(GO:0002851)
0.0 0.1 GO:1990426 homologous recombination-dependent replication fork processing(GO:1990426)
0.0 0.3 GO:0051410 detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.0 0.1 GO:0072114 cloaca development(GO:0035844) pronephric nephron tubule development(GO:0039020) pronephros morphogenesis(GO:0072114)
0.0 0.2 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.0 0.2 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.3 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.2 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.1 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.0 0.0 GO:0043323 positive regulation of natural killer cell degranulation(GO:0043323)
0.0 0.3 GO:0016556 mRNA modification(GO:0016556)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.7 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.2 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.0 GO:0061474 phagolysosome membrane(GO:0061474)
0.0 0.3 GO:0035686 sperm fibrous sheath(GO:0035686)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0008493 tetracycline transporter activity(GO:0008493)
0.1 0.3 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.3 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.3 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.1 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.1 GO:0000150 recombinase activity(GO:0000150)
0.0 0.2 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.0 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.0 0.2 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.3 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation