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avrg: GFI1 WT vs 36n/n vs KD

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Results for Nfatc1

Z-value: 5.23

Motif logo

Transcription factors associated with Nfatc1

Gene Symbol Gene ID Gene Info
ENSMUSG00000033016.17 nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nfatc1mm39_v1_chr18_-_80751327_807513950.771.3e-01Click!

Activity profile of Nfatc1 motif

Sorted Z-values of Nfatc1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_+_3000922 15.09 ENSMUST00000151376.3
predicted gene 10722
chr9_+_3023547 14.82 ENSMUST00000099046.4
predicted gene 10718
chr9_+_3013140 14.29 ENSMUST00000143083.3
predicted gene 10721
chr9_+_3027439 13.58 ENSMUST00000179982.2
ENSMUST00000177875.8
predicted gene 10717
chr9_+_3017408 12.16 ENSMUST00000099049.4
predicted gene 10719
chr9_+_3004457 12.15 ENSMUST00000178348.2
predicted gene 11168
chr9_+_3025417 12.01 ENSMUST00000075573.7
predicted gene 10717
chr9_+_3034599 11.63 ENSMUST00000178641.2
predicted gene, 17535
chr9_+_3005126 10.99 ENSMUST00000179881.2
predicted gene 11168
chr9_+_3018753 9.19 ENSMUST00000179272.2
predicted gene 10719
chr13_-_23945189 7.83 ENSMUST00000102964.4
H4 clustered histone 1
chr9_+_3032001 7.27 ENSMUST00000099056.4
ENSMUST00000179839.8
predicted gene 10717
chr9_+_3036877 7.26 ENSMUST00000155807.3
predicted gene 10715
chr9_+_3037111 7.08 ENSMUST00000177969.2
predicted gene 10715
chr9_+_3015654 6.75 ENSMUST00000099050.4
predicted gene 10720
chr2_-_98497609 5.52 ENSMUST00000099683.2
predicted gene 10800
chr12_+_33364288 3.56 ENSMUST00000144586.2
ataxin 7-like 1
chr7_-_85895409 3.53 ENSMUST00000165771.2
ENSMUST00000233075.2
ENSMUST00000233317.2
ENSMUST00000233312.2
ENSMUST00000233928.2
ENSMUST00000232799.2
ENSMUST00000233744.2
vomeronasal 2, receptor 76
chr2_+_98492576 3.50 ENSMUST00000099684.4
predicted gene 10801
chr15_+_6609322 3.13 ENSMUST00000090461.12
FYN binding protein
chr6_-_97408367 3.10 ENSMUST00000124050.3
FERM domain containing 4B
chr1_+_107456731 3.06 ENSMUST00000182198.8
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 10
chr7_-_126224848 2.84 ENSMUST00000032961.4
nuclear protein transcription regulator 1
chr10_+_40505985 2.81 ENSMUST00000019977.8
ENSMUST00000214102.2
ENSMUST00000213503.2
ENSMUST00000213442.2
ENSMUST00000216830.2
D-aspartate oxidase
chr13_+_23922783 2.80 ENSMUST00000040914.3
H1.2 linker histone, cluster member
chr11_-_11577824 2.52 ENSMUST00000081896.5
RIKEN cDNA 4930512M02 gene
chrX_-_9335525 2.48 ENSMUST00000015484.10
cytochrome b-245, beta polypeptide
chr2_+_30127692 2.41 ENSMUST00000113654.8
ENSMUST00000095078.3
leucine rich repeat containing 8A VRAC subunit A
chrX_+_158410229 2.37 ENSMUST00000112456.9
SH3-domain kinase binding protein 1
chr1_+_34044940 2.30 ENSMUST00000187486.7
ENSMUST00000182697.8
dystonin
chr2_-_87868043 2.16 ENSMUST00000129056.3
olfactory receptor 73
chr7_+_100435548 2.02 ENSMUST00000216021.2
family with sequence similarity 168, member A
chr18_-_80756273 1.98 ENSMUST00000078049.12
ENSMUST00000236711.2
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1
chr11_-_79421397 1.96 ENSMUST00000103236.4
ENSMUST00000170799.8
ENSMUST00000170422.4
ecotropic viral integration site 2a
ecotropic viral integration site 2
chr9_-_29874401 1.95 ENSMUST00000075069.11
neurotrimin
chrX_+_158410528 1.94 ENSMUST00000073094.10
SH3-domain kinase binding protein 1
chr10_-_12689345 1.88 ENSMUST00000217899.2
utrophin
chr11_-_73881233 1.88 ENSMUST00000214334.2
ENSMUST00000117510.4
olfactory receptor 398
chr2_-_87838612 1.87 ENSMUST00000215457.2
olfactory receptor 1160
chr6_-_57991216 1.80 ENSMUST00000228951.2
vomeronasal 1 receptor 26
chr7_+_101619897 1.79 ENSMUST00000211272.2
nuclear mitotic apparatus protein 1
chr6_-_28831746 1.76 ENSMUST00000062304.7
leucine rich repeat containing 4
chr14_-_50586329 1.74 ENSMUST00000216634.2
olfactory receptor 735
chr13_+_41013230 1.73 ENSMUST00000110191.10
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr4_-_135080471 1.69 ENSMUST00000084846.12
ENSMUST00000136342.9
ENSMUST00000105861.8
serine/arginine repetitive matrix 1
chr19_+_10502612 1.69 ENSMUST00000237321.2
ENSMUST00000038379.5
cleavage and polyadenylation specific factor 7
chr11_-_70545450 1.58 ENSMUST00000018437.3
profilin 1
chr7_+_102954855 1.56 ENSMUST00000214577.2
olfactory receptor 596
chr7_-_11414074 1.56 ENSMUST00000227010.2
ENSMUST00000209638.3
vomeronasal 1 receptor 72
chr15_-_58828321 1.55 ENSMUST00000228067.2
MTSS I-BAR domain containing 1
chr16_+_65317389 1.52 ENSMUST00000176330.8
ENSMUST00000004964.15
ENSMUST00000176038.8
POU domain, class 1, transcription factor 1
chr19_+_13339600 1.51 ENSMUST00000215096.2
olfactory receptor 1467
chr11_+_29413734 1.51 ENSMUST00000155854.8
coiled coil domain containing 88A
chr6_+_149211225 1.49 ENSMUST00000185930.2
retroelement silencing factor 1
chrX_-_37723943 1.49 ENSMUST00000058265.8
C1GALT1-specific chaperone 1
chr1_-_60082246 1.48 ENSMUST00000027172.13
ENSMUST00000191251.7
islet cell autoantigen 1-like
chr2_-_111779785 1.41 ENSMUST00000099604.6
olfactory receptor 1307
chr19_+_10502679 1.37 ENSMUST00000235674.2
cleavage and polyadenylation specific factor 7
chr17_-_35340189 1.37 ENSMUST00000025246.13
ENSMUST00000173114.8
casein kinase 2, beta polypeptide
chr12_-_99359265 1.35 ENSMUST00000177451.8
forkhead box N3
chr18_+_36693646 1.34 ENSMUST00000155329.9
ankyrin repeat and KH domain containing 1
chr18_+_36693024 1.33 ENSMUST00000134146.8
ankyrin repeat and KH domain containing 1
chr5_-_90031180 1.32 ENSMUST00000198151.2
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 3
chr6_+_15185202 1.32 ENSMUST00000154448.2
forkhead box P2
chr5_+_138228074 1.29 ENSMUST00000159798.8
ENSMUST00000159964.2
neurexophilin and PC-esterase domain family, member 5
chr2_+_89804937 1.28 ENSMUST00000214630.2
ENSMUST00000111512.10
ENSMUST00000144710.3
ENSMUST00000216678.2
olfactory receptor 1260
chr9_+_123901979 1.28 ENSMUST00000171719.8
chemokine (C-C motif) receptor 2
chr9_+_100525807 1.27 ENSMUST00000133388.2
stromal antigen 1
chr1_+_88022776 1.26 ENSMUST00000150634.8
ENSMUST00000058237.14
UDP glucuronosyltransferase 1 family, polypeptide A7C
chr6_+_149210889 1.23 ENSMUST00000130664.8
ENSMUST00000046689.13
retroelement silencing factor 1
chr3_-_64752138 1.19 ENSMUST00000177146.2
ENSMUST00000161972.10
predicted gene, 26939
vomeronasal 2, receptor 7
chr7_+_106737534 1.18 ENSMUST00000213367.3
ENSMUST00000214819.3
ENSMUST00000216871.3
ENSMUST00000215284.3
ENSMUST00000209942.2
olfactory receptor 716
chr19_-_10502468 1.18 ENSMUST00000025570.8
ENSMUST00000236455.2
succinate dehydrogenase complex assembly factor 2
chr9_-_123691077 1.17 ENSMUST00000182350.3
chemokine (C motif) receptor 1
chr16_+_43067641 1.16 ENSMUST00000079441.13
ENSMUST00000114691.8
zinc finger and BTB domain containing 20
chr15_-_9748863 1.13 ENSMUST00000159368.2
ENSMUST00000159093.8
ENSMUST00000162780.8
ENSMUST00000160236.8
ENSMUST00000208854.2
ENSMUST00000041840.14
sperm flagellar 2
chr14_+_35816874 1.13 ENSMUST00000226305.2
RIKEN cDNA 4930474N05 gene
chr18_+_31768126 1.12 ENSMUST00000234846.2
ENSMUST00000234772.2
Sin3A associated protein
chr6_+_149210941 1.10 ENSMUST00000190785.7
ENSMUST00000189932.7
ENSMUST00000100765.11
retroelement silencing factor 1
chr15_-_83135920 1.10 ENSMUST00000229687.2
ENSMUST00000164614.3
ENSMUST00000049530.14
alpha 1,4-galactosyltransferase
chr13_-_41513215 1.09 ENSMUST00000224803.2
neural precursor cell expressed, developmentally down-regulated gene 9
chr3_+_20043315 1.08 ENSMUST00000173779.2
ceruloplasmin
chr9_-_40366966 1.07 ENSMUST00000165104.8
ENSMUST00000045682.7
GRAM domain containing 1B
chrX_+_152281200 1.06 ENSMUST00000060714.10
ubiquilin 2
chr10_-_129524028 1.06 ENSMUST00000203785.3
ENSMUST00000217576.2
olfactory receptor 802
chr14_+_15749522 1.05 ENSMUST00000171987.2
predicted gene 8050
chr13_+_44884740 1.05 ENSMUST00000173246.8
jumonji, AT rich interactive domain 2
chr13_-_105191403 1.04 ENSMUST00000063551.7
regulator of G-protein signalling 7 binding protein
chr2_-_22930149 1.04 ENSMUST00000091394.13
ENSMUST00000093171.13
abl interactor 1
chr19_+_10366450 1.02 ENSMUST00000073899.6
synaptotagmin VII
chr7_+_75292971 0.99 ENSMUST00000207998.2
A kinase (PRKA) anchor protein 13
chr7_+_107497109 0.98 ENSMUST00000209670.4
ENSMUST00000216937.3
olfactory receptor 472
chr2_+_88217406 0.98 ENSMUST00000214040.3
olfactory receptor 1178
chr7_+_30252687 0.97 ENSMUST00000044048.8
heat shock protein, alpha-crystallin-related, B6
chr17_+_15262510 0.94 ENSMUST00000226561.2
ER membrane associated RNA degradation
chr14_-_20133246 0.93 ENSMUST00000059666.6
SAYSVFN motif domain containing 1
chr4_-_148021159 0.92 ENSMUST00000105712.2
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
chr2_-_113588983 0.92 ENSMUST00000099575.4
gremlin 1, DAN family BMP antagonist
chr11_-_65636651 0.89 ENSMUST00000138093.2
mitogen-activated protein kinase kinase 4
chr15_-_41733099 0.88 ENSMUST00000054742.7
actin-binding Rho activating protein
chr7_+_110372860 0.88 ENSMUST00000143786.2
adenosine monophosphate deaminase 3
chr2_-_73360069 0.87 ENSMUST00000094681.11
WAS/WASL interacting protein family, member 1
chr1_-_84816379 0.87 ENSMUST00000187818.2
thyroid hormone receptor interactor 12
chr13_+_83672389 0.85 ENSMUST00000200394.5
myocyte enhancer factor 2C
chr10_-_22025169 0.85 ENSMUST00000179054.8
ENSMUST00000069372.7
RIKEN cDNA E030030I06 gene
chrY_-_2663658 0.85 ENSMUST00000091178.2
sex determining region of Chr Y
chr7_-_29553079 0.85 ENSMUST00000108223.8
zinc finger protein 940
chr14_-_20027279 0.84 ENSMUST00000160013.8
guanine nucleotide binding protein (G protein), gamma 2
chr11_+_44508137 0.82 ENSMUST00000109268.2
ENSMUST00000101326.10
ENSMUST00000081265.12
early B cell factor 1
chr7_+_63835285 0.81 ENSMUST00000206263.2
ENSMUST00000206107.2
ENSMUST00000205731.2
ENSMUST00000206706.2
ENSMUST00000205690.2
transient receptor potential cation channel, subfamily M, member 1
chr9_+_100525501 0.81 ENSMUST00000146312.8
ENSMUST00000129269.8
stromal antigen 1
chr11_+_49410475 0.79 ENSMUST00000204706.3
olfactory receptor 1383
chr7_-_140087224 0.79 ENSMUST00000209873.2
ENSMUST00000064392.8
ENSMUST00000215768.2
ENSMUST00000215340.2
olfactory receptor 536
chr11_-_102907991 0.79 ENSMUST00000021313.9
dephospho-CoA kinase domain containing
chr5_+_117979899 0.78 ENSMUST00000142742.9
nitric oxide synthase 1, neuronal
chr2_-_22930104 0.78 ENSMUST00000153931.8
ENSMUST00000123948.8
abl interactor 1
chr1_+_24717722 0.78 ENSMUST00000186096.7
LMBR1 domain containing 1
chr8_+_34582184 0.76 ENSMUST00000095345.5
membrane bound O-acyltransferase domain containing 4
chr5_+_104350475 0.76 ENSMUST00000066708.7
dentin matrix protein 1
chr15_-_66673425 0.76 ENSMUST00000168589.8
src-like adaptor
chr8_+_66838927 0.75 ENSMUST00000039540.12
ENSMUST00000110253.3
membrane associated ring-CH-type finger 1
chr2_-_77000936 0.75 ENSMUST00000164114.9
ENSMUST00000049544.14
coiled-coil domain containing 141
chr11_-_98329782 0.73 ENSMUST00000002655.8
migration and invasion enhancer 1
chr17_-_37627945 0.72 ENSMUST00000217590.2
olfactory receptor 102
chr14_+_25842565 0.71 ENSMUST00000022416.15
annexin A11
chr3_-_113423774 0.71 ENSMUST00000092154.10
ENSMUST00000106536.8
ENSMUST00000106535.2
RNA-binding region (RNP1, RRM) containing 3
chr3_-_88366351 0.70 ENSMUST00000165898.8
ENSMUST00000127436.8
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chrX_-_16777913 0.70 ENSMUST00000040134.8
Norrie disease (pseudoglioma) (human)
chr14_-_54924062 0.69 ENSMUST00000147714.8
apoptotic chromatin condensation inducer 1
chr13_+_83672654 0.69 ENSMUST00000199019.5
myocyte enhancer factor 2C
chrX_-_125723491 0.68 ENSMUST00000081074.5
RIKEN cDNA 4932411N23 gene
chr4_+_86666764 0.68 ENSMUST00000045512.15
ENSMUST00000082026.14
DENN/MADD domain containing 4C
chr9_+_51959534 0.67 ENSMUST00000061352.11
radixin
chr15_+_101152078 0.66 ENSMUST00000228985.2
nuclear receptor subfamily 4, group A, member 1
chr7_-_45159790 0.66 ENSMUST00000211765.2
nucleobindin 1
chr3_+_90520408 0.65 ENSMUST00000198128.2
S100 calcium binding protein A6 (calcyclin)
chr8_-_105350898 0.64 ENSMUST00000212882.2
ENSMUST00000163783.4
cadherin 16
chr3_-_67371161 0.64 ENSMUST00000058981.3
latexin
chr3_+_123061094 0.63 ENSMUST00000047923.12
ENSMUST00000200333.2
Sec24 related gene family, member D (S. cerevisiae)
chr15_-_99717956 0.63 ENSMUST00000109024.9
LIM domain and actin binding 1
chr18_+_69726431 0.63 ENSMUST00000201091.4
ENSMUST00000201037.4
ENSMUST00000114977.5
transcription factor 4
chr1_-_155912216 0.62 ENSMUST00000027738.14
torsin A interacting protein 1
chr13_-_93774469 0.62 ENSMUST00000099309.6
betaine-homocysteine methyltransferase
chrX_-_104919201 0.62 ENSMUST00000198209.2
ATRX, chromatin remodeler
chr9_+_100525637 0.61 ENSMUST00000041418.13
stromal antigen 1
chr13_+_83652150 0.61 ENSMUST00000198199.5
myocyte enhancer factor 2C
chr2_-_22930188 0.61 ENSMUST00000114544.10
ENSMUST00000139038.8
ENSMUST00000126112.8
ENSMUST00000178908.2
ENSMUST00000078977.14
ENSMUST00000140164.8
ENSMUST00000149719.8
abl interactor 1
chr18_+_64387428 0.61 ENSMUST00000025477.15
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr2_-_88534814 0.60 ENSMUST00000216928.2
ENSMUST00000216977.2
olfactory receptor 1196
chr15_+_61857390 0.60 ENSMUST00000159327.2
ENSMUST00000167731.8
myelocytomatosis oncogene
chr9_-_37627519 0.59 ENSMUST00000215727.2
ENSMUST00000211952.3
olfactory receptor 160
chr6_-_41751648 0.59 ENSMUST00000214752.2
olfactory receptor 459
chr9_+_123902143 0.59 ENSMUST00000168841.3
ENSMUST00000055918.7
chemokine (C-C motif) receptor 2
chr14_+_52254341 0.59 ENSMUST00000228408.2
ENSMUST00000227295.2
transmembrane protein 253
chr8_+_107237483 0.58 ENSMUST00000080797.8
cadherin 3
chr4_+_155709275 0.58 ENSMUST00000067081.10
ENSMUST00000105600.8
ENSMUST00000105598.2
cyclin-dependent kinase 11B
chr13_-_67831586 0.56 ENSMUST00000137496.10
ENSMUST00000175678.2
ENSMUST00000175821.8
ENSMUST00000125495.10
zinc finger protein 738
chr5_-_121975676 0.56 ENSMUST00000197892.3
SH2B adaptor protein 3
chr3_+_90520176 0.56 ENSMUST00000001051.9
S100 calcium binding protein A6 (calcyclin)
chrX_-_104972938 0.55 ENSMUST00000198448.5
ENSMUST00000199233.5
ENSMUST00000134507.8
ENSMUST00000154866.8
ENSMUST00000128968.8
ENSMUST00000134381.8
ENSMUST00000150914.8
ATRX, chromatin remodeler
chr8_-_34575946 0.55 ENSMUST00000033913.11
dynactin 6
chr9_+_38340751 0.55 ENSMUST00000216502.3
ENSMUST00000216644.2
olfactory receptor 901
chr9_+_38725910 0.55 ENSMUST00000213164.2
olfactory receptor 922
chr6_-_48422447 0.54 ENSMUST00000114564.8
zinc finger protein 467
chr3_+_96603694 0.53 ENSMUST00000107076.10
protein inhibitor of activated STAT 3
chrX_-_163041185 0.53 ENSMUST00000112265.9
BMX non-receptor tyrosine kinase
chr1_-_131161312 0.53 ENSMUST00000212202.2
Ras association (RalGDS/AF-6) domain family member 5
chr10_-_86843878 0.52 ENSMUST00000035288.17
stabilin 2
chr14_-_54924382 0.52 ENSMUST00000022793.15
ENSMUST00000111484.9
apoptotic chromatin condensation inducer 1
chr4_-_148021217 0.51 ENSMUST00000019199.14
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
chrX_+_73298388 0.50 ENSMUST00000119197.8
ENSMUST00000088313.5
emerin
chr2_+_34999497 0.50 ENSMUST00000028235.11
ENSMUST00000156933.8
ENSMUST00000028237.15
ENSMUST00000113032.8
centriolin
chr17_+_34848507 0.48 ENSMUST00000015620.7
proline-rich transmembrane protein 1
chr1_-_169938060 0.48 ENSMUST00000027985.8
ENSMUST00000194690.6
discoidin domain receptor family, member 2
chr5_+_4073343 0.47 ENSMUST00000238634.2
A kinase (PRKA) anchor protein (yotiao) 9
chr1_+_4878046 0.47 ENSMUST00000027036.11
ENSMUST00000150971.8
ENSMUST00000119612.9
ENSMUST00000137887.8
ENSMUST00000115529.8
lysophospholipase 1
chr16_-_3535958 0.47 ENSMUST00000023180.15
Mediterranean fever
chr10_-_62343516 0.47 ENSMUST00000020271.13
serglycin
chr7_+_110373447 0.46 ENSMUST00000147587.2
adenosine monophosphate deaminase 3
chr18_-_55123153 0.46 ENSMUST00000064763.7
zinc finger protein 608
chr10_-_128246403 0.46 ENSMUST00000164664.8
nucleic acid binding protein 2
chr11_+_112673041 0.46 ENSMUST00000000579.3
SRY (sex determining region Y)-box 9
chr11_-_78074377 0.46 ENSMUST00000102483.5
ribosomal protein L23A
chr17_-_49871291 0.46 ENSMUST00000224595.2
ENSMUST00000057610.8
dishevelled associated activator of morphogenesis 2
chr10_+_42736345 0.45 ENSMUST00000063063.14
Scm polycomb group protein like 4
chr9_+_64292957 0.44 ENSMUST00000068967.11
multiple EGF-like-domains 11
chrX_-_47543029 0.44 ENSMUST00000114958.8
E74-like factor 4 (ets domain transcription factor)
chr9_-_60418286 0.44 ENSMUST00000098660.10
thrombospondin, type I, domain containing 4
chr1_+_24717793 0.42 ENSMUST00000186190.2
LMBR1 domain containing 1
chr9_+_64292908 0.42 ENSMUST00000093829.9
ENSMUST00000118485.8
ENSMUST00000164113.8
multiple EGF-like-domains 11
chr11_-_75918551 0.42 ENSMUST00000021207.7
refilin B
chr6_-_88022172 0.41 ENSMUST00000203674.3
ENSMUST00000204126.2
ENSMUST00000113596.8
ENSMUST00000113600.10
RAB7, member RAS oncogene family
chr16_+_8288627 0.40 ENSMUST00000046470.16
ENSMUST00000150790.2
ENSMUST00000142899.2
methyltransferase like 22
chr9_+_124195807 0.40 ENSMUST00000239563.2
protein phosphatase 2 (formerly 2A), regulatory subunit B'', delta
chr17_+_38082190 0.39 ENSMUST00000217119.2
olfactory receptor 122
chr9_+_65831489 0.39 ENSMUST00000130798.3
casein kinase 1, gamma 1
chr17_+_3447465 0.39 ENSMUST00000072156.7
T cell lymphoma invasion and metastasis 2
chr9_-_40015750 0.39 ENSMUST00000213858.2
olfactory receptor 984
chr1_+_88139678 0.38 ENSMUST00000073049.7
UDP glucuronosyltransferase 1 family, polypeptide A1
chrX_-_63320543 0.38 ENSMUST00000114679.2
ENSMUST00000069926.14
SLIT and NTRK-like family, member 4

Network of associatons between targets according to the STRING database.

First level regulatory network of Nfatc1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:0006533 aspartate catabolic process(GO:0006533)
0.7 2.0 GO:0060854 patterning of lymph vessels(GO:0060854)
0.6 1.9 GO:2000451 immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265) negative regulation of eosinophil activation(GO:1902567) positive regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000451)
0.5 2.0 GO:1905051 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.4 1.8 GO:1902846 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.4 1.3 GO:1900158 negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.4 1.3 GO:0006711 estrogen catabolic process(GO:0006711)
0.4 1.5 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.4 1.5 GO:0038016 insulin receptor internalization(GO:0038016)
0.4 1.4 GO:0034552 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.4 1.1 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.3 1.0 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.3 2.2 GO:0007527 adult somatic muscle development(GO:0007527)
0.3 2.5 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.3 1.4 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.3 0.8 GO:0071640 regulation of macrophage inflammatory protein 1 alpha production(GO:0071640)
0.3 1.5 GO:0034334 adherens junction maintenance(GO:0034334)
0.3 1.5 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.2 1.7 GO:0036438 maintenance of lens transparency(GO:0036438)
0.2 1.5 GO:0016266 O-glycan processing(GO:0016266)
0.2 0.8 GO:1901204 regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204)
0.2 0.6 GO:0048817 negative regulation of hair follicle maturation(GO:0048817)
0.2 1.2 GO:1901581 post-embryonic appendage morphogenesis(GO:0035120) post-embryonic limb morphogenesis(GO:0035127) post-embryonic forelimb morphogenesis(GO:0035128) telomeric repeat-containing RNA transcription(GO:0097393) telomeric repeat-containing RNA transcription from RNA pol II promoter(GO:0097394) regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901580) negative regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901581) positive regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901582)
0.2 1.1 GO:0001575 globoside metabolic process(GO:0001575)
0.2 1.3 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.2 1.0 GO:0086023 adrenergic receptor signaling pathway involved in heart process(GO:0086023)
0.2 0.3 GO:1990927 calcium ion regulated lysosome exocytosis(GO:1990927)
0.2 2.8 GO:2000194 regulation of female gonad development(GO:2000194)
0.2 0.5 GO:0072034 intrahepatic bile duct development(GO:0035622) renal vesicle induction(GO:0072034)
0.2 0.8 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.2 1.2 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.2 2.4 GO:0002329 pre-B cell differentiation(GO:0002329)
0.1 0.6 GO:0090095 lactic acid secretion(GO:0046722) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.1 0.9 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.1 0.1 GO:0034118 erythrocyte aggregation(GO:0034117) regulation of erythrocyte aggregation(GO:0034118)
0.1 1.3 GO:0032264 IMP salvage(GO:0032264)
0.1 0.4 GO:0018879 biphenyl metabolic process(GO:0018879)
0.1 0.8 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.1 0.6 GO:1990743 protein sialylation(GO:1990743)
0.1 0.5 GO:0033367 protein localization to secretory granule(GO:0033366) protein localization to mast cell secretory granule(GO:0033367) protease localization to mast cell secretory granule(GO:0033368) maintenance of protein location in mast cell secretory granule(GO:0033370) T cell secretory granule organization(GO:0033371) maintenance of protease location in mast cell secretory granule(GO:0033373) protein localization to T cell secretory granule(GO:0033374) protease localization to T cell secretory granule(GO:0033375) maintenance of protein location in T cell secretory granule(GO:0033377) maintenance of protease location in T cell secretory granule(GO:0033379) granzyme B localization to T cell secretory granule(GO:0033380) maintenance of granzyme B location in T cell secretory granule(GO:0033382)
0.1 1.8 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.1 0.6 GO:0071267 amino acid salvage(GO:0043102) L-methionine salvage(GO:0071267)
0.1 0.4 GO:1903542 negative regulation of exosomal secretion(GO:1903542)
0.1 1.6 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.1 0.3 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 2.3 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 1.4 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.1 0.3 GO:0031554 regulation of DNA-templated transcription, termination(GO:0031554)
0.1 0.9 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 0.7 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 1.4 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.1 1.2 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 0.7 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.1 0.9 GO:0003185 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 0.5 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.2 GO:0015734 beta-alanine transport(GO:0001762) taurine transport(GO:0015734)
0.1 2.4 GO:0072673 lamellipodium morphogenesis(GO:0072673)
0.1 0.1 GO:0071350 interleukin-15-mediated signaling pathway(GO:0035723) cellular response to interleukin-15(GO:0071350)
0.1 3.1 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 0.4 GO:1902966 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.1 0.6 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 0.2 GO:0043382 positive regulation of memory T cell differentiation(GO:0043382)
0.1 0.9 GO:0030238 male sex determination(GO:0030238)
0.1 1.1 GO:0007288 sperm axoneme assembly(GO:0007288)
0.1 0.4 GO:1904587 response to glycoprotein(GO:1904587)
0.0 1.3 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.3 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.4 GO:0036309 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.0 0.1 GO:0090673 endothelial cell-matrix adhesion(GO:0090673)
0.0 0.4 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.0 0.8 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.5 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 1.4 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.6 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.2 GO:0009115 xanthine catabolic process(GO:0009115)
0.0 0.8 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.1 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.0 3.1 GO:0045576 mast cell activation(GO:0045576)
0.0 1.1 GO:0046688 response to copper ion(GO:0046688)
0.0 0.6 GO:0050961 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.1 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.5 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.1 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 1.0 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 0.3 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 9.5 GO:0050907 detection of chemical stimulus involved in sensory perception(GO:0050907)
0.0 0.4 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 1.2 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.0 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.0 0.2 GO:0001866 NK T cell proliferation(GO:0001866)
0.0 0.4 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.8 GO:0051642 centrosome localization(GO:0051642)
0.0 0.2 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.2 GO:0007320 insemination(GO:0007320)
0.0 0.5 GO:0070200 establishment of protein localization to telomere(GO:0070200)
0.0 0.2 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.2 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.0 0.5 GO:0010842 retina layer formation(GO:0010842)
0.0 0.3 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 0.6 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.5 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.6 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.0 GO:0009624 response to nematode(GO:0009624) eosinophil differentiation(GO:0030222)
0.0 0.9 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 1.7 GO:0019236 response to pheromone(GO:0019236)
0.0 0.2 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.6 GO:0031529 ruffle organization(GO:0031529)
0.0 0.1 GO:0035989 tendon development(GO:0035989)
0.0 0.1 GO:1900141 regulation of oligodendrocyte apoptotic process(GO:1900141) negative regulation of oligodendrocyte apoptotic process(GO:1900142) cholangiocyte apoptotic process(GO:1902488) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.3 2.3 GO:0031673 H zone(GO:0031673)
0.3 1.4 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.2 1.2 GO:1990707 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
0.2 0.8 GO:0035841 new growing cell tip(GO:0035841)
0.2 2.4 GO:0031209 SCAR complex(GO:0031209)
0.2 2.5 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 1.2 GO:0061574 ASAP complex(GO:0061574)
0.1 0.7 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.1 1.1 GO:0002177 manchette(GO:0002177)
0.1 0.5 GO:0044307 dendritic branch(GO:0044307)
0.1 1.3 GO:0032009 early phagosome(GO:0032009)
0.1 2.2 GO:0070938 contractile ring(GO:0070938)
0.1 0.5 GO:0070876 SOSS complex(GO:0070876)
0.1 2.2 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.1 1.2 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.5 GO:0042629 mast cell granule(GO:0042629)
0.0 0.5 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 1.2 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.2 GO:0002079 inner acrosomal membrane(GO:0002079)
0.0 0.7 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.3 GO:0033263 CORVET complex(GO:0033263)
0.0 0.4 GO:0097208 extrinsic component of vacuolar membrane(GO:0000306) alveolar lamellar body(GO:0097208)
0.0 0.7 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.5 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.4 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.7 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.4 GO:0051286 cell tip(GO:0051286)
0.0 0.5 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.6 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.2 GO:0042555 MCM complex(GO:0042555)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.6 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.8 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.6 1.9 GO:0035717 chemokine (C-C motif) ligand 7 binding(GO:0035717)
0.4 1.7 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.4 2.0 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.3 1.4 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.3 0.8 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.2 0.9 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.2 2.5 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.2 2.4 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.2 1.5 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.2 1.2 GO:0015616 DNA translocase activity(GO:0015616)
0.2 0.8 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 0.9 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 1.6 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 1.5 GO:0031419 cobalamin binding(GO:0031419)
0.1 1.3 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.4 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.1 2.1 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 0.6 GO:0008172 S-methyltransferase activity(GO:0008172)
0.1 1.0 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 1.1 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 1.8 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 1.2 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.1 0.8 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.3 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.2 GO:0001761 beta-alanine transmembrane transporter activity(GO:0001761) taurine transmembrane transporter activity(GO:0005368) taurine:sodium symporter activity(GO:0005369)
0.1 0.5 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 2.2 GO:0017166 vinculin binding(GO:0017166)
0.1 1.1 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.1 0.7 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.3 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 1.5 GO:0043422 protein kinase B binding(GO:0043422)
0.1 1.2 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.8 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 2.2 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.5 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.5 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.9 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.4 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.0 0.4 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.9 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.2 GO:0016623 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.1 GO:0048030 disaccharide binding(GO:0048030)
0.0 0.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 1.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.0 0.2 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 1.4 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.1 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.0 0.5 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.3 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.9 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.6 GO:0005521 lamin binding(GO:0005521)
0.0 0.4 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.7 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.9 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.4 GO:0001972 retinoic acid binding(GO:0001972)
0.0 1.0 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.5 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.5 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 1.0 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.1 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.3 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.0 GO:0001607 neuromedin U receptor activity(GO:0001607)
0.0 19.9 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 1.7 GO:0005550 pheromone binding(GO:0005550)
0.0 0.8 GO:0008374 O-acyltransferase activity(GO:0008374)
0.0 0.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.0 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0 0.6 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.7 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.7 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 0.9 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 2.4 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.9 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 3.2 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 2.3 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 2.3 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 1.8 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.8 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 1.1 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.5 PID EPO PATHWAY EPO signaling pathway
0.0 0.9 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.9 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 4.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.9 PID BMP PATHWAY BMP receptor signaling
0.0 0.4 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.7 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.4 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.9 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.4 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.5 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.6 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.2 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.9 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.1 3.1 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 3.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 3.8 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.1 3.3 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 1.7 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.1 1.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 0.8 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 2.7 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 1.1 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 2.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.4 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 1.0 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.4 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.1 REACTOME DEFENSINS Genes involved in Defensins
0.0 0.8 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 1.0 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.7 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.6 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.9 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 1.4 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 1.5 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.6 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.3 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.7 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.6 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.5 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 1.4 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.7 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.2 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE