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avrg: GFI1 WT vs 36n/n vs KD

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Results for Nfatc3

Z-value: 2.25

Motif logo

Transcription factors associated with Nfatc3

Gene Symbol Gene ID Gene Info
ENSMUSG00000031902.11 nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nfatc3mm39_v1_chr8_+_106786190_1067862651.003.3e-04Click!

Activity profile of Nfatc3 motif

Sorted Z-values of Nfatc3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_142326363 1.62 ENSMUST00000165774.8
guanylate binding protein 2
chr10_+_4561974 1.48 ENSMUST00000105590.8
ENSMUST00000067086.14
estrogen receptor 1 (alpha)
chr11_+_48977852 1.45 ENSMUST00000046704.7
ENSMUST00000203810.3
ENSMUST00000203149.3
interferon gamma inducible protein 47
olfactory receptor 56
chr7_+_46496929 1.42 ENSMUST00000132157.2
ENSMUST00000210631.2
lactate dehydrogenase A
chr7_+_46496552 1.35 ENSMUST00000005051.6
lactate dehydrogenase A
chr7_+_46496506 1.31 ENSMUST00000209984.2
lactate dehydrogenase A
chr7_+_100143250 1.24 ENSMUST00000153287.8
uncoupling protein 2 (mitochondrial, proton carrier)
chr5_-_88675700 1.20 ENSMUST00000087033.6
immunoglobulin joining chain
chr9_-_105398346 1.18 ENSMUST00000176770.8
ENSMUST00000085133.13
ATPase, Ca++-sequestering
chr3_-_61273228 1.17 ENSMUST00000066298.3
RIKEN cDNA B430305J03 gene
chr2_-_32602246 1.16 ENSMUST00000155205.2
ENSMUST00000120105.8
cyclin-dependent kinase 9 (CDC2-related kinase)
chr7_+_100142977 1.14 ENSMUST00000129324.8
uncoupling protein 2 (mitochondrial, proton carrier)
chr11_+_98938137 1.13 ENSMUST00000140772.2
insulin-like growth factor binding protein 4
chr11_+_48977888 1.02 ENSMUST00000214804.2
interferon gamma inducible protein 47
chrX_+_138464065 1.02 ENSMUST00000113027.8
ring finger protein 128
chr10_+_7543260 0.92 ENSMUST00000040135.9
nucleoporin 43
chr9_+_88209250 0.86 ENSMUST00000034992.8
5' nucleotidase, ecto
chr8_+_85696695 0.80 ENSMUST00000164807.2
peroxiredoxin 2
chr14_+_43951187 0.79 ENSMUST00000094051.6
predicted gene 7324
chr8_+_85696453 0.78 ENSMUST00000125893.8
peroxiredoxin 2
chr5_+_117501557 0.78 ENSMUST00000111959.2
WD repeat and SOCS box-containing 2
chr15_+_4055865 0.77 ENSMUST00000110690.9
3-oxoacid CoA transferase 1
chr15_-_98851566 0.70 ENSMUST00000097014.7
tubulin, alpha 1A
chr8_+_85696396 0.70 ENSMUST00000109733.8
peroxiredoxin 2
chr8_+_3565401 0.69 ENSMUST00000207146.2
ENSMUST00000208002.2
patatin-like phospholipase domain containing 6
chr6_+_30401864 0.69 ENSMUST00000068240.13
ENSMUST00000068259.10
ENSMUST00000132581.8
kelch domain containing 10
chr1_-_93373145 0.66 ENSMUST00000186787.7
high density lipoprotein (HDL) binding protein
chr14_+_8348779 0.66 ENSMUST00000022256.5
proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
chr7_-_28649094 0.64 ENSMUST00000148196.3
actinin alpha 4
chr15_+_8138805 0.63 ENSMUST00000230017.2
nucleoporin 155
chr11_-_3864664 0.63 ENSMUST00000109995.2
ENSMUST00000051207.2
solute carrier family 35, member E4
chr5_-_148329615 0.63 ENSMUST00000138257.8
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr14_+_79753055 0.62 ENSMUST00000110835.3
ENSMUST00000227192.2
E74-like factor 1
chr14_+_55797443 0.61 ENSMUST00000117236.8
DDB1 and CUL4 associated factor 11
chr11_-_80030735 0.61 ENSMUST00000136996.2
transcription elongation factor, mitochondrial
chr12_+_52550775 0.61 ENSMUST00000219443.2
Rho GTPase activating protein 5
chr8_+_3565377 0.60 ENSMUST00000111070.4
ENSMUST00000004681.14
ENSMUST00000208310.2
patatin-like phospholipase domain containing 6
chr19_-_42741148 0.60 ENSMUST00000236659.2
ENSMUST00000076505.4
pyridine nucleotide-disulphide oxidoreductase domain 2
chr9_-_99450948 0.60 ENSMUST00000035043.12
armadillo repeat containing 8
chr17_+_73144531 0.58 ENSMUST00000233886.2
yippee like 5
chr5_+_110478558 0.57 ENSMUST00000112481.2
polymerase (DNA directed), epsilon
chr17_-_35827676 0.56 ENSMUST00000160885.2
ENSMUST00000159009.2
ENSMUST00000161012.8
transcription factor 19
chr13_+_49735938 0.56 ENSMUST00000221170.2
osteomodulin
chr10_+_80905869 0.56 ENSMUST00000005057.7
thimet oligopeptidase 1
chrX_-_153999440 0.56 ENSMUST00000026318.15
spermidine/spermine N1-acetyl transferase 1
chr2_-_25498459 0.56 ENSMUST00000058137.9
RAB, member RAS oncogene family-like 6
chr3_+_89987749 0.56 ENSMUST00000127955.2
tropomyosin 3, gamma
chr3_-_37180093 0.56 ENSMUST00000029275.6
interleukin 2
chr3_+_159545309 0.56 ENSMUST00000068952.10
ENSMUST00000198878.2
wntless WNT ligand secretion mediator
chr5_-_21087023 0.55 ENSMUST00000118174.8
putative homeodomain transcription factor 2
chr13_-_6698751 0.55 ENSMUST00000021614.14
ENSMUST00000138703.8
phosphofructokinase, platelet
chr12_-_55045887 0.54 ENSMUST00000173529.2
bromodomain adjacent to zinc finger domain 1A
chr3_-_94566107 0.53 ENSMUST00000196655.5
ENSMUST00000200407.2
ENSMUST00000006123.11
ENSMUST00000196733.5
tuftelin 1
chr7_-_45480200 0.53 ENSMUST00000107723.9
ENSMUST00000131384.3
glutamate-rich WD repeat containing 1
chr8_-_85696369 0.53 ENSMUST00000109736.9
ENSMUST00000140561.8
ribonuclease H2, large subunit
chr5_+_44070486 0.53 ENSMUST00000122204.3
ENSMUST00000200338.2
predicted pseudogene 7879
chr19_+_24853039 0.52 ENSMUST00000073080.7
predicted gene 10053
chr6_+_18848570 0.51 ENSMUST00000056398.11
LSM8 homolog, U6 small nuclear RNA associated
chr17_-_45903410 0.51 ENSMUST00000166119.8
solute carrier family 29 (nucleoside transporters), member 1
chr2_+_21210527 0.49 ENSMUST00000054591.10
ENSMUST00000102952.8
ENSMUST00000138965.8
ENSMUST00000138914.8
ENSMUST00000102951.2
threonine synthase-like 1 (bacterial)
chr1_+_152683568 0.49 ENSMUST00000190323.7
neutrophil cytosolic factor 2
chrX_-_8059597 0.49 ENSMUST00000143223.2
ENSMUST00000033509.15
phenylalkylamine Ca2+ antagonist (emopamil) binding protein
chr1_+_87998487 0.49 ENSMUST00000073772.5
UDP glucuronosyltransferase 1 family, polypeptide A9
chr6_+_18848600 0.49 ENSMUST00000201141.3
LSM8 homolog, U6 small nuclear RNA associated
chr12_+_31704853 0.48 ENSMUST00000036862.5
component of oligomeric golgi complex 5
chr14_-_75991903 0.48 ENSMUST00000049168.9
component of oligomeric golgi complex 3
chr3_+_84859453 0.48 ENSMUST00000029727.8
F-box and WD-40 domain protein 7
chr7_+_130179063 0.47 ENSMUST00000207918.2
ENSMUST00000215492.2
ENSMUST00000084513.12
ENSMUST00000059145.14
transforming, acidic coiled-coil containing protein 2
chr9_+_65370077 0.47 ENSMUST00000215170.2
SPG21, maspardin
chr12_-_31704766 0.47 ENSMUST00000020977.4
dihydrouridine synthase 4-like (S. cerevisiae)
chr10_+_61516078 0.47 ENSMUST00000220372.2
ENSMUST00000020285.10
ENSMUST00000219506.2
ENSMUST00000218474.2
secretion associated Ras related GTPase 1A
chr15_+_41694317 0.47 ENSMUST00000166917.3
ENSMUST00000230127.2
ENSMUST00000230131.2
oxidation resistance 1
chr15_+_102381705 0.47 ENSMUST00000229958.2
ENSMUST00000229184.2
ENSMUST00000230728.2
ENSMUST00000230114.2
poly(rC) binding protein 2
chr11_+_95557783 0.47 ENSMUST00000125172.8
ENSMUST00000036374.6
prohibitin
chr10_-_57408512 0.46 ENSMUST00000169122.8
serine incorporator 1
chr10_-_53952686 0.46 ENSMUST00000220088.2
mannosidase 1, alpha
chr9_+_54858388 0.46 ENSMUST00000171900.2
proteasome subunit alpha 4
chr8_-_46605196 0.45 ENSMUST00000110378.9
sorting nexin 25
chr1_-_106641940 0.45 ENSMUST00000112751.2
B cell leukemia/lymphoma 2
chr7_+_27186335 0.45 ENSMUST00000008528.8
SERTA domain containing 1
chr7_-_126873219 0.45 ENSMUST00000082428.6
selenophosphate synthetase 2
chr1_-_16689660 0.45 ENSMUST00000117146.9
ubiquitin-conjugating enzyme E2W (putative)
chr15_-_98432111 0.45 ENSMUST00000116400.4
ENSMUST00000023727.17
ENSMUST00000230542.2
KAT8 regulatory NSL complex subunit 2
chr2_+_61542038 0.44 ENSMUST00000028278.14
proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
chr10_+_53472853 0.44 ENSMUST00000219271.2
anti-silencing function 1A histone chaperone
chr9_+_56344700 0.44 ENSMUST00000239472.2
ubiquitin-conjugating enzyme E2S (Ube2s) retrogene
chr12_-_85335193 0.43 ENSMUST00000121930.2
acylphosphatase 1, erythrocyte (common) type
chr3_+_88523730 0.43 ENSMUST00000175779.8
rho/rac guanine nucleotide exchange factor (GEF) 2
chr16_-_19801781 0.42 ENSMUST00000058839.10
kelch-like 6
chr4_-_129452180 0.42 ENSMUST00000067240.11
lymphocyte protein tyrosine kinase
chr17_-_37269330 0.42 ENSMUST00000113669.9
RNA polymerase I subunit H
chr11_+_109376432 0.42 ENSMUST00000106697.8
arylsulfatase G
chr7_-_126073994 0.41 ENSMUST00000205733.2
ENSMUST00000205889.2
SH2B adaptor protein 1
chrX_-_153999333 0.41 ENSMUST00000112551.4
spermidine/spermine N1-acetyl transferase 1
chr7_-_126074222 0.41 ENSMUST00000205497.2
SH2B adaptor protein 1
chr7_-_103928939 0.40 ENSMUST00000051795.10
tripartite motif-containing 5
chr13_+_93441307 0.40 ENSMUST00000080127.12
homer scaffolding protein 1
chr7_-_5128936 0.40 ENSMUST00000147835.4
RAS-like, family 2, locus 9
chr16_-_91723870 0.40 ENSMUST00000159295.8
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
chr15_-_66703471 0.40 ENSMUST00000164163.8
src-like adaptor
chr4_-_129452148 0.40 ENSMUST00000167288.8
ENSMUST00000134336.3
lymphocyte protein tyrosine kinase
chr19_+_56414114 0.39 ENSMUST00000238892.2
caspase 7
chr18_+_69633741 0.39 ENSMUST00000207214.2
ENSMUST00000201094.4
ENSMUST00000200703.4
ENSMUST00000202765.4
transcription factor 4
chr3_+_87432879 0.39 ENSMUST00000170036.8
ENSMUST00000117293.2
ets variant 3
chr6_+_127423779 0.39 ENSMUST00000112191.8
poly (ADP-ribose) polymerase family, member 11
chr14_+_19801333 0.39 ENSMUST00000022340.5
nidogen 2
chr5_+_33815466 0.39 ENSMUST00000074849.13
ENSMUST00000079534.11
ENSMUST00000201633.2
transforming, acidic coiled-coil containing protein 3
chr16_+_35892437 0.38 ENSMUST00000163352.9
ENSMUST00000231468.2
coiled-coil domain containing 58
chr2_-_125701059 0.38 ENSMUST00000110463.8
ENSMUST00000028635.6
COP9 signalosome subunit 2
chr13_+_69950509 0.37 ENSMUST00000223376.2
ENSMUST00000222387.2
mediator complex subunit 10
chr9_+_96140781 0.37 ENSMUST00000190104.7
ENSMUST00000179416.8
ENSMUST00000189606.7
transcription factor Dp 2
chr1_-_180021039 0.37 ENSMUST00000160482.8
ENSMUST00000170472.8
coenzyme Q8A
chr2_-_181223787 0.36 ENSMUST00000057816.15
uridine-cytidine kinase 1-like 1
chr8_+_106412905 0.36 ENSMUST00000213019.2
capping protein regulator and myosin 1 linker 2
chr6_-_72357398 0.36 ENSMUST00000101285.10
ENSMUST00000074231.6
vesicle-associated membrane protein 5
chr12_+_111409087 0.36 ENSMUST00000109792.8
tumor necrosis factor, alpha-induced protein 2
chr17_-_37269425 0.36 ENSMUST00000172518.8
RNA polymerase I subunit H
chr2_+_125701054 0.36 ENSMUST00000028636.13
ENSMUST00000125084.8
galactokinase 2
chr12_+_4684620 0.35 ENSMUST00000217672.2
intersectin 2
chr2_+_35172392 0.35 ENSMUST00000028239.8
gelsolin
chr1_-_181039509 0.34 ENSMUST00000162819.9
ENSMUST00000237749.2
WD repeat domain 26
chr7_-_126074256 0.34 ENSMUST00000205440.2
ENSMUST00000032978.8
ENSMUST00000205340.2
SH2B adaptor protein 1
chr15_-_83316995 0.34 ENSMUST00000165095.9
protein kinase C and casein kinase substrate in neurons 2
chr8_-_94739469 0.34 ENSMUST00000053766.14
autocrine motility factor receptor
chr4_+_86493905 0.34 ENSMUST00000091064.8
Ras-related GTP binding A
chr12_+_84332006 0.34 ENSMUST00000123614.8
ENSMUST00000147363.8
ENSMUST00000135001.8
ENSMUST00000146377.8
prostaglandin reductase 2
chr6_-_71609881 0.34 ENSMUST00000065509.11
ENSMUST00000207023.2
lysine (K)-specific demethylase 3A
chr11_+_54517164 0.34 ENSMUST00000239168.2
Rap guanine nucleotide exchange factor (GEF) 6
chr5_-_88823049 0.34 ENSMUST00000133532.8
ENSMUST00000150438.2
G-rich RNA sequence binding factor 1
chrX_+_152506577 0.34 ENSMUST00000140575.8
ENSMUST00000208373.2
ENSMUST00000185492.7
ENSMUST00000149514.8
negative regulator of P-body association
chr14_-_47059546 0.33 ENSMUST00000226937.2
glia maturation factor, beta
chr14_+_55797468 0.33 ENSMUST00000147981.2
ENSMUST00000133256.8
DDB1 and CUL4 associated factor 11
chr13_+_93441447 0.33 ENSMUST00000109497.8
ENSMUST00000109498.8
ENSMUST00000060490.11
ENSMUST00000109492.9
ENSMUST00000109496.8
ENSMUST00000109495.8
homer scaffolding protein 1
chr1_+_171041539 0.33 ENSMUST00000005820.11
ENSMUST00000075469.12
ENSMUST00000155126.8
nuclear receptor subfamily 1, group I, member 3
chrX_-_47602395 0.33 ENSMUST00000114945.9
ENSMUST00000037349.8
apoptosis-inducing factor, mitochondrion-associated 1
chr18_+_67338437 0.33 ENSMUST00000210564.3
charged multivesicular body protein 1B
chr2_-_125700905 0.33 ENSMUST00000110462.8
COP9 signalosome subunit 2
chr15_-_10470575 0.33 ENSMUST00000136591.8
DnaJ heat shock protein family (Hsp40) member C21
chr15_-_83317020 0.32 ENSMUST00000231184.2
protein kinase C and casein kinase substrate in neurons 2
chr5_-_123126550 0.32 ENSMUST00000086200.11
ENSMUST00000156474.8
lysine (K)-specific demethylase 2B
chr5_-_23821523 0.32 ENSMUST00000088392.9
serine/arginine-rich protein specific kinase 2
chr4_+_155896946 0.32 ENSMUST00000030944.11
cyclin L2
chr12_+_10440755 0.32 ENSMUST00000020947.7
retinol dehydrogenase 14 (all-trans and 9-cis)
chr6_+_54249817 0.31 ENSMUST00000204921.3
ENSMUST00000203091.3
ENSMUST00000204115.3
ENSMUST00000203941.3
ENSMUST00000204746.2
chimerin 2
chr8_-_84831391 0.31 ENSMUST00000041367.9
ENSMUST00000210279.2
DDB1 and CUL4 associated factor 15
chr14_-_55897854 0.31 ENSMUST00000002400.7
magnesium-dependent phosphatase 1
chr3_+_85946145 0.31 ENSMUST00000238331.2
SH3 domain protein D19
chrX_-_133501677 0.31 ENSMUST00000239113.2
galactosidase, alpha
chr15_-_100322934 0.30 ENSMUST00000123461.8
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr11_-_121095462 0.30 ENSMUST00000026169.7
2-oxoglutarate and iron-dependent oxygenase domain containing 3
chr6_+_29853745 0.30 ENSMUST00000064872.13
ENSMUST00000152581.8
ENSMUST00000176265.8
ENSMUST00000154079.8
S-adenosylhomocysteine hydrolase-like 2
chr1_+_55276336 0.30 ENSMUST00000061334.10
methionine-tRNA synthetase 2 (mitochondrial)
chr13_-_114524586 0.30 ENSMUST00000232101.2
ENSMUST00000225978.3
NADH:ubiquinone oxidoreductase core subunit S4
chr17_+_36152559 0.30 ENSMUST00000174124.2
mediator of DNA damage checkpoint 1
chr3_-_51468236 0.29 ENSMUST00000037141.9
SET domain containing (lysine methyltransferase) 7
chr6_-_51443602 0.29 ENSMUST00000203253.2
heterogeneous nuclear ribonucleoprotein A2/B1
chr4_-_63779562 0.29 ENSMUST00000030047.3
tumor necrosis factor (ligand) superfamily, member 8
chr6_-_129449739 0.29 ENSMUST00000112076.9
ENSMUST00000184581.3
C-type lectin domain family 7, member a
chr5_-_105198913 0.29 ENSMUST00000112718.5
guanylate-binding protein 8
chr17_-_45903494 0.29 ENSMUST00000163492.8
solute carrier family 29 (nucleoside transporters), member 1
chr13_+_25127127 0.28 ENSMUST00000021773.13
glycosylphosphatidylinositol specific phospholipase D1
chr4_+_43406435 0.28 ENSMUST00000098106.9
ENSMUST00000139198.2
RUN and SH3 domain containing 2
chr7_-_99994257 0.28 ENSMUST00000207634.2
protein phosphatase methylesterase 1
chr13_+_16189041 0.28 ENSMUST00000164993.2
inhibin beta-A
chrX_-_133501874 0.28 ENSMUST00000033621.8
galactosidase, alpha
chr18_+_24087725 0.27 ENSMUST00000225682.2
ENSMUST00000060762.6
zinc finger protein 397
chr2_+_23046381 0.27 ENSMUST00000028117.4
YME1-like 1 (S. cerevisiae)
chr7_-_130148984 0.27 ENSMUST00000160289.9
NSE4 homolog A, SMC5-SMC6 complex component
chr17_+_28988354 0.26 ENSMUST00000233109.2
ENSMUST00000004986.14
mitogen-activated protein kinase 13
chr11_+_48977495 0.26 ENSMUST00000152914.2
interferon gamma inducible protein 47
chr17_+_6320731 0.26 ENSMUST00000088940.6
transmembrane protein 181A
chr5_+_3393893 0.26 ENSMUST00000165117.8
ENSMUST00000197385.2
cyclin-dependent kinase 6
chr6_+_3498382 0.26 ENSMUST00000001412.17
ENSMUST00000170873.10
ENSMUST00000164052.5
VPS50 EARP/GARPII complex subunit
chr14_-_72840373 0.26 ENSMUST00000162825.8
fibronectin type III domain containing 3A
chr7_-_126483851 0.26 ENSMUST00000071268.11
ENSMUST00000117394.2
TAO kinase 2
chr9_-_37166699 0.26 ENSMUST00000161114.2
solute carrier family 37 (glycerol-3-phosphate transporter), member 2
chr5_-_130284366 0.26 ENSMUST00000026387.11
SBDS ribosome maturation factor
chr10_-_44334711 0.26 ENSMUST00000039174.11
PR domain containing 1, with ZNF domain
chr11_-_83421333 0.25 ENSMUST00000035938.3
chemokine (C-C motif) ligand 5
chr15_-_91075933 0.25 ENSMUST00000069511.8
ATP-binding cassette, sub-family D (ALD), member 2
chr14_-_52248324 0.24 ENSMUST00000226964.2
zinc finger protein 219
chr18_+_37858753 0.24 ENSMUST00000066149.9
protocadherin gamma subfamily A, 8
chr6_+_134807097 0.24 ENSMUST00000046303.12
cAMP responsive element binding protein-like 2
chr6_+_71350411 0.24 ENSMUST00000066747.14
CD8 antigen, alpha chain
chr6_+_48818567 0.23 ENSMUST00000203639.3
transmembrane protein 176A
chr19_-_6947112 0.23 ENSMUST00000025912.10
phospholipase C, beta 3
chrX_-_101687813 0.23 ENSMUST00000052012.14
ENSMUST00000043596.12
ENSMUST00000119229.8
ENSMUST00000122022.8
ENSMUST00000120270.8
ENSMUST00000113611.3
phosphorylase kinase alpha 1
chr11_-_107238956 0.23 ENSMUST00000134763.2
phosphatidylinositol transfer protein, cytoplasmic 1
chr14_+_56905698 0.23 ENSMUST00000116468.2
M-phase phosphoprotein 8
chr17_+_29898221 0.22 ENSMUST00000129864.2
cap methyltransferase 1
chr16_+_43960183 0.22 ENSMUST00000159514.8
ENSMUST00000161326.8
ENSMUST00000063520.15
ENSMUST00000063542.8
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr17_-_52133594 0.22 ENSMUST00000129667.8
ENSMUST00000169480.8
ENSMUST00000148559.2
special AT-rich sequence binding protein 1
chr1_-_16689527 0.22 ENSMUST00000182554.9
ubiquitin-conjugating enzyme E2W (putative)
chr3_-_53370621 0.22 ENSMUST00000056749.14
NHL repeat containing 3
chr8_-_46577183 0.22 ENSMUST00000170416.8
sorting nexin 25
chr9_+_118307412 0.22 ENSMUST00000035020.15
eomesodermin
chr17_+_26780486 0.21 ENSMUST00000001619.16
endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
chr12_-_101784727 0.21 ENSMUST00000222587.2
fibulin 5
chr10_-_118705029 0.21 ENSMUST00000004281.10
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr16_-_43959559 0.20 ENSMUST00000063661.13
ENSMUST00000114666.9
ATPase, H+ transporting, lysosomal V1 subunit A

Network of associatons between targets according to the STRING database.

First level regulatory network of Nfatc3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.1 GO:0019659 glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.3 1.2 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.3 1.2 GO:0032468 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.2 1.5 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.2 0.9 GO:0046086 adenosine biosynthetic process(GO:0046086)
0.2 1.0 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.2 1.2 GO:2001168 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.2 2.3 GO:0002536 respiratory burst involved in inflammatory response(GO:0002536)
0.2 0.6 GO:0045004 DNA replication proofreading(GO:0045004)
0.2 0.6 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.2 0.7 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.2 0.6 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.2 0.8 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 0.4 GO:0033082 regulation of extrathymic T cell differentiation(GO:0033082)
0.1 0.4 GO:2000813 negative regulation of barbed-end actin filament capping(GO:2000813)
0.1 2.4 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 0.5 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1 0.3 GO:0070194 synaptonemal complex disassembly(GO:0070194)
0.1 0.8 GO:0015862 uridine transport(GO:0015862)
0.1 0.5 GO:0006742 NADP catabolic process(GO:0006742)
0.1 0.3 GO:1990428 miRNA transport(GO:1990428)
0.1 0.5 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.1 0.5 GO:0045917 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.1 0.5 GO:0032847 cochlear nucleus development(GO:0021747) regulation of cellular pH reduction(GO:0032847)
0.1 0.5 GO:0015676 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.1 0.4 GO:1903921 renal protein absorption(GO:0097017) protein processing in phagocytic vesicle(GO:1900756) positive regulation of keratinocyte apoptotic process(GO:1902174) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923)
0.1 0.5 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 0.3 GO:0036275 response to 5-fluorouracil(GO:0036275)
0.1 0.6 GO:2000320 negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.1 0.3 GO:0021993 initiation of neural tube closure(GO:0021993)
0.1 4.4 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.1 0.4 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.1 0.6 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.1 0.6 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.1 0.1 GO:0033092 positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.1 0.3 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.1 0.4 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 0.2 GO:1903538 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.1 0.2 GO:0002631 regulation of granuloma formation(GO:0002631) negative regulation of granuloma formation(GO:0002632) regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573)
0.1 0.2 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 0.4 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.1 1.1 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.1 0.3 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1 0.8 GO:0070474 positive regulation of uterine smooth muscle contraction(GO:0070474)
0.1 0.3 GO:0060279 positive regulation of ovulation(GO:0060279)
0.1 0.4 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
0.1 0.3 GO:0035063 nuclear speck organization(GO:0035063)
0.1 0.4 GO:0043097 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0 0.6 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.1 GO:0003032 detection of oxygen(GO:0003032)
0.0 0.3 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.5 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.2 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0 0.2 GO:0097309 cap1 mRNA methylation(GO:0097309)
0.0 0.6 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.3 GO:0006116 NADH oxidation(GO:0006116)
0.0 0.8 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.7 GO:0070836 caveola assembly(GO:0070836)
0.0 0.1 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822)
0.0 0.2 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.0 0.4 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.6 GO:0015809 arginine transport(GO:0015809)
0.0 0.7 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.3 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.7 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.3 GO:0042256 mature ribosome assembly(GO:0042256)
0.0 0.9 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.3 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.3 GO:0009405 pathogenesis(GO:0009405)
0.0 0.4 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.2 GO:0035660 MyD88-dependent toll-like receptor 4 signaling pathway(GO:0035660)
0.0 0.3 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.6 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:0001762 beta-alanine transport(GO:0001762) taurine transport(GO:0015734)
0.0 0.2 GO:1904219 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.3 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.5 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.1 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.0 0.2 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.0 0.3 GO:1902510 regulation of apoptotic DNA fragmentation(GO:1902510)
0.0 0.0 GO:0060161 positive regulation of dopamine receptor signaling pathway(GO:0060161)
0.0 0.5 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.0 0.4 GO:0000054 ribosomal subunit export from nucleus(GO:0000054) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753)
0.0 0.2 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 0.3 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.1 GO:0031959 mineralocorticoid receptor signaling pathway(GO:0031959)
0.0 0.5 GO:0006743 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744)
0.0 0.2 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 1.0 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.4 GO:0051601 exocyst localization(GO:0051601)
0.0 0.5 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 1.1 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.0 0.2 GO:1902177 positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902177)
0.0 0.2 GO:0010909 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909)
0.0 0.1 GO:0061295 regulation of pronephros size(GO:0035565) hepatoblast differentiation(GO:0061017) mesonephros morphogenesis(GO:0061206) mesonephric nephron development(GO:0061215) mesonephric nephron morphogenesis(GO:0061228) mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis(GO:0061235) regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061295) negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061296) mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:1901146)
0.0 0.4 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0 0.1 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.2 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.0 0.6 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.3 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.0 0.1 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 0.7 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0 0.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.4 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.0 GO:0031448 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.0 0.3 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 1.1 GO:0045840 positive regulation of mitotic nuclear division(GO:0045840)
0.0 0.1 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.1 GO:0090400 stress-induced premature senescence(GO:0090400)
0.0 0.4 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 0.1 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.4 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.5 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.4 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.2 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.1 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.0 0.2 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.5 GO:0042036 negative regulation of cytokine biosynthetic process(GO:0042036)
0.0 0.2 GO:0099628 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.0 0.2 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.0 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.0 0.2 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 1.4 GO:0051028 mRNA transport(GO:0051028)
0.0 0.0 GO:0019413 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate metabolic process(GO:0019541) propionate biosynthetic process(GO:0019542)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0002756 MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.0 0.1 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.2 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 4.0 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 0.5 GO:0008623 CHRAC(GO:0008623)
0.1 0.5 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 1.6 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.1 0.6 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 0.5 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 0.7 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 0.3 GO:0043512 inhibin A complex(GO:0043512)
0.1 0.5 GO:0070826 paraferritin complex(GO:0070826)
0.1 1.2 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.1 0.5 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 0.3 GO:0097132 cyclin D2-CDK6 complex(GO:0097132)
0.1 1.0 GO:0005688 U6 snRNP(GO:0005688)
0.1 0.3 GO:1990130 Iml1 complex(GO:1990130) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.9 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 1.0 GO:0017119 Golgi transport complex(GO:0017119)
0.1 0.3 GO:1990745 EARP complex(GO:1990745)
0.0 0.1 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 0.7 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.4 GO:0070847 core mediator complex(GO:0070847)
0.0 0.2 GO:0071953 elastic fiber(GO:0071953)
0.0 1.1 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 0.4 GO:1990462 omegasome(GO:1990462)
0.0 0.5 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.4 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.5 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.4 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.4 GO:0030478 actin cap(GO:0030478)
0.0 0.5 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.2 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.6 GO:0031143 pseudopodium(GO:0031143)
0.0 0.3 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.3 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.2 GO:0005610 laminin-5 complex(GO:0005610)
0.0 1.1 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.1 GO:0045160 myosin I complex(GO:0045160)
0.0 0.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.3 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.9 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.3 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 1.0 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 0.7 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.5 GO:0046930 pore complex(GO:0046930)
0.0 0.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.2 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.4 GO:0000145 exocyst(GO:0000145)
0.0 0.7 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.8 GO:0001772 immunological synapse(GO:0001772)
0.0 0.7 GO:0043034 costamere(GO:0043034)
0.0 0.5 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.6 GO:0002102 podosome(GO:0002102)
0.0 0.8 GO:0008180 COP9 signalosome(GO:0008180)
0.0 1.1 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 1.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.2 GO:0031011 Ino80 complex(GO:0031011)
0.0 2.9 GO:0043209 myelin sheath(GO:0043209)
0.0 0.0 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.4 1.2 GO:0019862 IgA binding(GO:0019862)
0.4 2.4 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.4 4.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.3 1.2 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.2 1.0 GO:0019809 spermidine binding(GO:0019809)
0.2 0.6 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.2 0.6 GO:0052692 raffinose alpha-galactosidase activity(GO:0052692)
0.2 0.8 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.2 0.8 GO:0042610 CD8 receptor binding(GO:0042610)
0.2 0.5 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.2 2.3 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 0.4 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.1 0.4 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.1 0.5 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 1.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.4 GO:0045159 myosin II binding(GO:0045159)
0.1 0.5 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 0.4 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 1.2 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 0.6 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.5 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 0.3 GO:0047522 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.1 0.3 GO:0030298 receptor signaling protein tyrosine kinase activator activity(GO:0030298) CCR1 chemokine receptor binding(GO:0031726)
0.1 0.5 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 0.6 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.1 0.5 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 0.7 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.1 0.5 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.1 0.3 GO:1904288 BAT3 complex binding(GO:1904288)
0.1 0.3 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 0.3 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 0.3 GO:0098770 FBXO family protein binding(GO:0098770)
0.1 0.2 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.1 0.7 GO:0046972 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.1 0.6 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1 0.5 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 0.4 GO:0004849 uridine kinase activity(GO:0004849)
0.0 1.4 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.5 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.3 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.8 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.3 GO:1990715 mRNA CDS binding(GO:1990715)
0.0 0.5 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.4 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.2 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.0 0.3 GO:0015119 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.9 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.5 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.3 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 1.0 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.5 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.2 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.3 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.1 GO:0001761 beta-alanine transmembrane transporter activity(GO:0001761) taurine transmembrane transporter activity(GO:0005368) taurine:sodium symporter activity(GO:0005369)
0.0 0.1 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.0 0.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.4 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.4 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.2 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.5 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.8 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.3 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.2 GO:0031812 beta-1 adrenergic receptor binding(GO:0031697) G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.2 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.0 0.7 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.2 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.3 GO:0008106 alcohol dehydrogenase (NADP+) activity(GO:0008106)
0.0 0.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.5 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 6.2 GO:0003924 GTPase activity(GO:0003924)
0.0 0.3 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 0.1 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.0 0.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.2 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.4 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.4 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.3 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.3 GO:0051861 glycolipid binding(GO:0051861)
0.0 0.2 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.3 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0043426 MRF binding(GO:0043426)
0.0 0.2 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.2 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.2 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.6 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.7 GO:0008307 structural constituent of muscle(GO:0008307)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 5.1 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 2.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.8 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 2.3 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.1 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.0 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.7 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.5 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.5 PID MYC PATHWAY C-MYC pathway
0.0 1.1 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.1 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 1.0 PID E2F PATHWAY E2F transcription factor network
0.0 0.4 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.4 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.4 PID ALK1 PATHWAY ALK1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.1 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.1 0.8 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 1.0 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 1.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.4 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.9 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.6 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 1.6 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 1.2 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.7 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.6 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 0.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 3.1 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 0.4 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.6 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 1.6 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.7 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.4 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 1.1 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.9 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.6 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.6 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.8 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.2 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.9 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.6 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.7 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.1 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.6 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.2 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity