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avrg: GFI1 WT vs 36n/n vs KD

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Results for Nfe2_Bach1_Mafk

Z-value: 3.22

Motif logo

Transcription factors associated with Nfe2_Bach1_Mafk

Gene Symbol Gene ID Gene Info
ENSMUSG00000058794.13 nuclear factor, erythroid derived 2
ENSMUSG00000025612.6 BTB and CNC homology 1, basic leucine zipper transcription factor 1
ENSMUSG00000018143.11 v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nfe2mm39_v1_chr15_-_103161237_103161256-0.838.3e-02Click!
Mafkmm39_v1_chr5_+_139777263_1397772710.731.6e-01Click!
Bach1mm39_v1_chr16_+_87495792_87495872-0.474.2e-01Click!

Activity profile of Nfe2_Bach1_Mafk motif

Sorted Z-values of Nfe2_Bach1_Mafk motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_126398165 3.87 ENSMUST00000205890.2
ENSMUST00000205336.2
ENSMUST00000087566.11
aldolase A, fructose-bisphosphate
chr4_-_57956411 3.45 ENSMUST00000030051.6
thioredoxin 1
chr17_-_45883421 3.14 ENSMUST00000130406.2
heat shock protein 90 alpha (cytosolic), class B member 1
chr4_+_116543045 2.90 ENSMUST00000129315.8
ENSMUST00000106470.8
peroxiredoxin 1
chr18_-_43610829 2.46 ENSMUST00000057110.11
eukaryotic translation initiation factor 3, subunit J2
chr14_-_36857202 2.08 ENSMUST00000165649.4
ENSMUST00000224769.2
growth hormone inducible transmembrane protein
chr6_-_16898440 2.02 ENSMUST00000031533.11
transcription factor EC
chr12_+_71021395 1.92 ENSMUST00000160027.8
ENSMUST00000160864.8
proteasome subunit alpha 3
chr16_+_20470402 1.91 ENSMUST00000007212.9
ENSMUST00000232629.2
proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
chr4_+_116542741 1.80 ENSMUST00000135573.8
ENSMUST00000151129.8
peroxiredoxin 1
chr12_-_40298072 1.75 ENSMUST00000169926.8
interferon-related developmental regulator 1
chr14_+_67953547 1.71 ENSMUST00000078053.13
potassium channel tetramerisation domain containing 9
chr19_-_4092218 1.66 ENSMUST00000237999.2
ENSMUST00000042700.12
glutathione S-transferase, pi 2
chr18_-_35087355 1.59 ENSMUST00000025217.11
heat shock protein 9
chr11_+_50101717 1.58 ENSMUST00000147468.8
mannoside acetylglucosaminyltransferase 4, isoenzyme B
chr16_+_90017634 1.58 ENSMUST00000023707.11
superoxide dismutase 1, soluble
chr18_-_10030017 1.49 ENSMUST00000116669.2
ENSMUST00000092096.14
ubiquitin specific peptidase 14
chr11_-_48762170 1.37 ENSMUST00000049519.4
ENSMUST00000097271.4
immunity-related GTPase family M member 1
chr17_-_45884179 1.35 ENSMUST00000165127.8
ENSMUST00000166469.8
ENSMUST00000024739.14
heat shock protein 90 alpha (cytosolic), class B member 1
chr14_-_36857083 1.35 ENSMUST00000042564.17
growth hormone inducible transmembrane protein
chr5_-_92496730 1.27 ENSMUST00000038816.13
ENSMUST00000118006.3
chemokine (C-X-C motif) ligand 10
chr7_+_127399776 1.27 ENSMUST00000046863.12
ENSMUST00000206674.2
ENSMUST00000106272.8
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr19_-_4087907 1.25 ENSMUST00000237982.2
glutathione S-transferase, pi 1
chr7_+_127399789 1.23 ENSMUST00000125188.8
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr2_+_151947444 1.20 ENSMUST00000041500.8
sulfiredoxin 1 homolog (S. cerevisiae)
chr12_+_82303350 1.14 ENSMUST00000222714.2
signal-induced proliferation-associated 1 like 1
chr19_-_32080496 1.14 ENSMUST00000235213.2
ENSMUST00000236504.2
N-acylsphingosine amidohydrolase 2
chr14_+_67953687 1.11 ENSMUST00000150768.8
potassium channel tetramerisation domain containing 9
chr10_-_117215920 1.09 ENSMUST00000175924.2
cleavage and polyadenylation specific factor 6
chr14_-_79539063 1.03 ENSMUST00000022595.8
regulator of cell cycle
chr5_-_65585720 1.01 ENSMUST00000131263.3
UDP-glucose dehydrogenase
chr2_+_164790139 0.99 ENSMUST00000017881.3
matrix metallopeptidase 9
chr14_+_8348779 0.97 ENSMUST00000022256.5
proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
chr1_+_165596961 0.96 ENSMUST00000040298.5
cellular repressor of E1A-stimulated genes 1
chr8_+_95710977 0.95 ENSMUST00000093271.8
adhesion G protein-coupled receptor G1
chr11_-_74614654 0.94 ENSMUST00000102520.9
platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
chr8_-_25581354 0.94 ENSMUST00000125466.2
pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2
chr2_+_150412329 0.94 ENSMUST00000089200.3
cystatin F (leukocystatin)
chr12_+_55445560 0.92 ENSMUST00000021412.9
proteasome subunit alpha 6
chrX_+_73468140 0.90 ENSMUST00000135165.8
ENSMUST00000114128.8
ENSMUST00000004330.10
ENSMUST00000114133.9
ENSMUST00000114129.9
ENSMUST00000132749.2
inhibitor of kappaB kinase gamma
chr11_+_78069477 0.87 ENSMUST00000092880.14
ENSMUST00000127587.8
TLC domain containing 1
chr16_+_20367327 0.85 ENSMUST00000003319.6
ENSMUST00000232680.2
ENSMUST00000232490.2
ATP-binding cassette, sub-family F (GCN20), member 3
chr8_-_108315024 0.84 ENSMUST00000044106.6
proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
chr11_-_30599510 0.82 ENSMUST00000074613.4
acylphosphatase 2, muscle type
chr1_-_75195127 0.81 ENSMUST00000079464.13
tubulin, alpha 4A
chr9_-_21150350 0.81 ENSMUST00000049567.10
ENSMUST00000193982.2
kelch-like ECH-associated protein 1
chr4_-_126215462 0.80 ENSMUST00000102617.5
ADP-ribosylserine hydrolase
chr6_+_129510117 0.78 ENSMUST00000032264.9
gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1
chr7_-_112946481 0.78 ENSMUST00000117577.8
BTB (POZ) domain containing 10
chr12_+_111505253 0.78 ENSMUST00000220803.2
eukaryotic translation initiation factor 5
chr1_+_85992341 0.78 ENSMUST00000027432.9
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
chrX_-_133483849 0.76 ENSMUST00000113213.2
ENSMUST00000033617.13
Bruton agammaglobulinemia tyrosine kinase
chr12_+_111504450 0.72 ENSMUST00000166123.9
ENSMUST00000222441.2
eukaryotic translation initiation factor 5
chr3_-_116301684 0.69 ENSMUST00000153005.2
RNA 3'-terminal phosphate cyclase
chrX_-_165992145 0.69 ENSMUST00000112176.8
thymosin, beta 4, X chromosome
chr9_+_107445101 0.68 ENSMUST00000192887.6
ENSMUST00000195752.6
hyaluronoglucosaminidase 2
chrX_+_163052367 0.68 ENSMUST00000145412.8
ENSMUST00000033749.9
pirin
chr9_-_21150523 0.68 ENSMUST00000194542.6
ENSMUST00000216436.2
kelch-like ECH-associated protein 1
chr5_+_136996713 0.68 ENSMUST00000001790.6
claudin 15
chr4_-_42168603 0.67 ENSMUST00000098121.4
predicted gene 13305
chr5_-_21990170 0.66 ENSMUST00000115193.8
ENSMUST00000115192.2
ENSMUST00000115195.8
ENSMUST00000030771.12
DnaJ heat shock protein family (Hsp40) member C2
chr4_-_42665763 0.66 ENSMUST00000238770.2
interleukin 11 receptor, alpha chain 2
chr12_-_101943134 0.66 ENSMUST00000221227.2
NADH:ubiquinone oxidoreductase subunit B1
chr11_+_76836330 0.65 ENSMUST00000021197.10
bleomycin hydrolase
chr11_+_120564185 0.65 ENSMUST00000135346.8
ENSMUST00000127269.8
ENSMUST00000131727.9
ENSMUST00000149389.8
ENSMUST00000153346.8
alveolar soft part sarcoma chromosome region, candidate 1 (human)
chr2_+_163389068 0.63 ENSMUST00000109411.8
ENSMUST00000018094.13
hepatic nuclear factor 4, alpha
chrX_+_158155171 0.62 ENSMUST00000087143.7
eukaryotic translation initiation factor 1A, X-linked
chr7_+_127400016 0.62 ENSMUST00000106271.2
ENSMUST00000138432.2
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr4_+_155606919 0.61 ENSMUST00000177094.8
guanine nucleotide binding protein (G protein), beta 1
chr18_+_77017713 0.61 ENSMUST00000026487.6
ENSMUST00000136800.2
immediate early response 3 interacting protein 1
chr14_+_79753055 0.61 ENSMUST00000110835.3
ENSMUST00000227192.2
E74-like factor 1
chr11_-_50101592 0.61 ENSMUST00000143379.2
ENSMUST00000015981.12
ENSMUST00000102774.11
sequestosome 1
chr19_-_4087940 0.60 ENSMUST00000237893.2
ENSMUST00000169613.4
glutathione S-transferase, pi 1
chr12_+_111505216 0.60 ENSMUST00000050993.11
eukaryotic translation initiation factor 5
chr7_+_127728712 0.59 ENSMUST00000033053.8
ENSMUST00000205460.2
integrin alpha X
chr13_-_23894697 0.59 ENSMUST00000091707.13
ENSMUST00000006787.8
homeostatic iron regulator
chr1_+_135945705 0.58 ENSMUST00000063719.15
transmembrane protein 9
chr19_-_8690330 0.58 ENSMUST00000206598.2
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
chr18_+_12776358 0.57 ENSMUST00000234966.2
ENSMUST00000025294.9
tetratricopeptide repeat domain 39C
chr7_+_49408847 0.57 ENSMUST00000085272.7
ENSMUST00000207895.2
HIV-1 Tat interactive protein 2
chr10_-_121462219 0.57 ENSMUST00000039810.8
ENSMUST00000218004.2
exportin, tRNA (nuclear export receptor for tRNAs)
chr17_+_35268942 0.56 ENSMUST00000007257.10
chloride intracellular channel 1
chr1_+_135945798 0.56 ENSMUST00000117950.2
transmembrane protein 9
chr7_-_113875261 0.56 ENSMUST00000135570.8
proteasome subunit alpha 1
chr8_-_48128164 0.56 ENSMUST00000080353.3
inhibitor of growth family, member 2
chr17_-_45903410 0.55 ENSMUST00000166119.8
solute carrier family 29 (nucleoside transporters), member 1
chr7_-_19005721 0.54 ENSMUST00000032561.9
vasodilator-stimulated phosphoprotein
chr15_-_83006289 0.54 ENSMUST00000166019.2
ribosomal RNA processing 7 homolog A
chr12_-_84447702 0.53 ENSMUST00000122194.8
ectonucleoside triphosphate diphosphohydrolase 5
chr11_+_76836545 0.53 ENSMUST00000125145.8
bleomycin hydrolase
chr6_-_67014348 0.53 ENSMUST00000204369.2
growth arrest and DNA-damage-inducible 45 alpha
chr2_-_25114660 0.53 ENSMUST00000043584.5
tubulin, beta 4B class IVB
chr7_+_126843446 0.52 ENSMUST00000052509.6
zinc finger protein 771
chr5_+_138115165 0.52 ENSMUST00000062350.15
ENSMUST00000110961.9
ENSMUST00000080732.10
ENSMUST00000110960.9
ENSMUST00000142185.8
ENSMUST00000136425.2
ENSMUST00000110959.2
zinc finger and SCAN domain containing 21
chr13_-_55677109 0.51 ENSMUST00000223563.2
docking protein 3
chr14_+_55129950 0.51 ENSMUST00000140691.8
poly(A) binding protein, nuclear 1
chr15_-_79718423 0.50 ENSMUST00000109623.8
ENSMUST00000109625.8
ENSMUST00000023060.13
ENSMUST00000089299.6
chromobox 6
neuronal pentraxin chromo domain
chr12_-_84447625 0.49 ENSMUST00000117286.2
ectonucleoside triphosphate diphosphohydrolase 5
chr14_-_55950545 0.49 ENSMUST00000002389.9
ENSMUST00000226907.2
transglutaminase 1, K polypeptide
chr4_-_136613498 0.48 ENSMUST00000046384.9
complement component 1, q subcomponent, beta polypeptide
chr1_+_127234441 0.48 ENSMUST00000171405.2
mannoside acetylglucosaminyltransferase 5
chr14_+_67953584 0.48 ENSMUST00000145542.8
ENSMUST00000125212.2
potassium channel tetramerisation domain containing 9
chr7_-_33929667 0.48 ENSMUST00000206415.2
glucose-6-phosphate isomerase 1
chr3_+_28859585 0.48 ENSMUST00000043867.11
ENSMUST00000194649.2
ribosomal protein L22 like 1
chrX_+_161684221 0.47 ENSMUST00000101095.9
cytidine 5'-triphosphate synthase 2
chr2_+_90884349 0.46 ENSMUST00000067663.14
ENSMUST00000002171.14
ENSMUST00000111441.10
proteasome (prosome, macropain) 26S subunit, ATPase 3
chr11_+_106146966 0.46 ENSMUST00000021049.9
protease (prosome, macropain) 26S subunit, ATPase 5
chr18_+_38088597 0.46 ENSMUST00000070709.9
ENSMUST00000177058.8
ENSMUST00000169360.9
ENSMUST00000163591.9
ENSMUST00000091932.12
RELT-like 2
chr18_-_64649497 0.46 ENSMUST00000237351.2
ENSMUST00000236186.2
ENSMUST00000235325.2
asparaginyl-tRNA synthetase
chr4_-_58912678 0.45 ENSMUST00000144512.8
ENSMUST00000102889.10
ENSMUST00000055822.15
Ecm29 proteasome adaptor and scaffold
chr5_-_122639840 0.45 ENSMUST00000177974.8
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr2_+_11710246 0.45 ENSMUST00000148748.8
interleukin 15 receptor, alpha chain
chr13_-_8921732 0.45 ENSMUST00000054251.13
ENSMUST00000176813.8
ENSMUST00000175958.2
WD repeat domain 37
chr8_-_127672590 0.45 ENSMUST00000179857.3
ENSMUST00000212771.2
translocase of outer mitochondrial membrane 20
chr10_+_4561974 0.45 ENSMUST00000105590.8
ENSMUST00000067086.14
estrogen receptor 1 (alpha)
chr11_+_60619224 0.44 ENSMUST00000018743.5
mitochondrial elongation factor 2
chr5_+_25452342 0.44 ENSMUST00000114950.2
polypeptide N-acetylgalactosaminyltransferase 11
chr6_+_138118565 0.44 ENSMUST00000118091.8
microsomal glutathione S-transferase 1
chr19_-_41252370 0.43 ENSMUST00000237871.2
ENSMUST00000025989.10
transmembrane 9 superfamily member 3
chr12_+_111504640 0.43 ENSMUST00000222375.2
ENSMUST00000222388.2
eukaryotic translation initiation factor 5
chr9_+_5298669 0.43 ENSMUST00000238505.2
caspase 1
chr7_+_120516967 0.43 ENSMUST00000207481.2
ENSMUST00000106483.4
ENSMUST00000033173.15
polymerase (RNA) III (DNA directed) polypeptide E
chr11_-_43638790 0.43 ENSMUST00000048578.3
ENSMUST00000109278.8
tetratricopeptide repeat domain 1
chr11_+_60428788 0.42 ENSMUST00000044250.4
alkB homolog 5, RNA demethylase
chr14_-_52257113 0.42 ENSMUST00000166169.4
ENSMUST00000226605.2
zinc finger protein 219
chr10_+_128641663 0.42 ENSMUST00000218511.2
DnaJ heat shock protein family (Hsp40) member C14
chr10_+_115979787 0.42 ENSMUST00000105271.9
protein tyrosine phosphatase, receptor type, R
chr2_+_153491363 0.41 ENSMUST00000072997.10
ENSMUST00000109773.8
ENSMUST00000109774.9
ENSMUST00000081628.13
ENSMUST00000103151.8
ENSMUST00000056495.14
ENSMUST00000088976.12
ENSMUST00000109772.8
ENSMUST00000103150.10
DNA methyltransferase 3B
chr1_-_88437617 0.41 ENSMUST00000067625.9
glutamine repeat protein 1
chr11_-_120520954 0.40 ENSMUST00000106180.2
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
chr2_+_90884612 0.40 ENSMUST00000185715.7
proteasome (prosome, macropain) 26S subunit, ATPase 3
chr6_+_51500881 0.40 ENSMUST00000049152.15
sorting nexin 10
chr6_-_67512768 0.40 ENSMUST00000058178.6
tumor-associated calcium signal transducer 2
chr12_+_51737775 0.40 ENSMUST00000218820.2
ENSMUST00000021338.10
adaptor-related protein complex AP-4, sigma 1
chr9_-_21150100 0.39 ENSMUST00000164812.8
kelch-like ECH-associated protein 1
chr4_-_43558386 0.39 ENSMUST00000130353.2
talin 1
chr4_-_140501507 0.39 ENSMUST00000026381.7
peptidyl arginine deiminase, type IV
chr9_+_108566513 0.39 ENSMUST00000192344.2
protein kinase, cAMP dependent regulatory, type II alpha
chr9_-_60594742 0.38 ENSMUST00000114032.8
ENSMUST00000166168.8
ENSMUST00000132366.2
leucine rich repeat containing 49
chr11_-_120521382 0.38 ENSMUST00000106181.8
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
chr17_+_25059079 0.38 ENSMUST00000164251.8
hydroxyacyl glutathione hydrolase
chr19_+_8816663 0.38 ENSMUST00000160556.8
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr12_-_85335193 0.38 ENSMUST00000121930.2
acylphosphatase 1, erythrocyte (common) type
chr14_-_20443676 0.38 ENSMUST00000061444.5
mitochondrial ribosomal protein S16
chr16_-_22258469 0.37 ENSMUST00000079601.13
ets variant 5
chr10_+_128626772 0.37 ENSMUST00000219404.2
ENSMUST00000026411.8
matrix metallopeptidase 19
chr7_-_104002534 0.37 ENSMUST00000130139.3
ENSMUST00000059037.15
tripartite motif-containing 12C
chr18_-_64649620 0.36 ENSMUST00000025483.11
ENSMUST00000237400.2
asparaginyl-tRNA synthetase
chr3_+_95836558 0.36 ENSMUST00000165307.8
ENSMUST00000015893.13
ENSMUST00000169426.8
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr2_+_118731860 0.36 ENSMUST00000036578.7
bromo adjacent homology domain containing 1
chr9_+_54858388 0.36 ENSMUST00000171900.2
proteasome subunit alpha 4
chr2_-_25162347 0.35 ENSMUST00000028342.7
SS nuclear autoantigen 1
chr11_-_78402931 0.35 ENSMUST00000052566.8
transmembrane protein 199
chr2_-_20948230 0.34 ENSMUST00000140230.2
Rho GTPase activating protein 21
chr1_-_30988772 0.34 ENSMUST00000238874.2
ENSMUST00000027232.15
ENSMUST00000076587.6
ENSMUST00000233506.2
protein tyrosine phosphatase 4a1
chr9_-_103243039 0.34 ENSMUST00000035484.11
carnitine deficiency-associated gene expressed in ventricle 3
chr3_+_88243562 0.34 ENSMUST00000001451.11
Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans)
chrX_-_37341274 0.34 ENSMUST00000089056.10
ENSMUST00000089054.11
ENSMUST00000066498.8
transmembrane protein 255A
chr10_-_43777712 0.34 ENSMUST00000020012.7
glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1
chr15_+_80139371 0.33 ENSMUST00000109605.5
ENSMUST00000229828.2
activating transcription factor 4
chr6_-_120334400 0.33 ENSMUST00000112703.8
coiled-coil domain containing 77
chr16_-_18161746 0.33 ENSMUST00000231372.2
ENSMUST00000130752.2
ENSMUST00000231605.2
ENSMUST00000115628.10
transport and golgi organization 2
chr4_-_109333866 0.33 ENSMUST00000030284.10
ring finger protein 11
chr6_-_67014191 0.31 ENSMUST00000204282.2
growth arrest and DNA-damage-inducible 45 alpha
chr11_-_50216426 0.31 ENSMUST00000179865.8
ENSMUST00000020637.9
calnexin
chr7_-_33929708 0.31 ENSMUST00000038027.6
glucose-6-phosphate isomerase 1
chr8_-_70389147 0.30 ENSMUST00000212277.2
GATA zinc finger domain containing 2A
chr7_-_113875342 0.30 ENSMUST00000033008.10
proteasome subunit alpha 1
chr11_-_106146868 0.29 ENSMUST00000021048.7
FtsJ RNA methyltransferase homolog 3 (E. coli)
chr9_+_64024429 0.29 ENSMUST00000034969.14
lactase-like
chr7_+_127160751 0.28 ENSMUST00000190278.3
transmembrane protein 265
chr11_-_109364424 0.28 ENSMUST00000070152.12
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr11_-_4799345 0.28 ENSMUST00000053079.13
ENSMUST00000109910.9
neurofibromin 2
chr11_-_116080361 0.27 ENSMUST00000148601.2
acyl-Coenzyme A oxidase 1, palmitoyl
chr2_+_163837423 0.27 ENSMUST00000131288.2
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
chr6_-_86770504 0.27 ENSMUST00000204441.3
ENSMUST00000204398.2
ENSMUST00000001187.15
annexin A4
chr7_-_126074222 0.27 ENSMUST00000205497.2
SH2B adaptor protein 1
chr17_-_56440817 0.27 ENSMUST00000167545.3
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chr8_+_111782951 0.26 ENSMUST00000210390.2
exosome component 6
chr19_+_56414114 0.26 ENSMUST00000238892.2
caspase 7
chr12_+_86999366 0.26 ENSMUST00000191463.2
CLOCK interacting protein, circadian
chr10_+_127894816 0.26 ENSMUST00000052798.14
prostaglandin E synthase 3
chr8_-_68427217 0.25 ENSMUST00000098696.10
ENSMUST00000038959.16
ENSMUST00000093469.11
pleckstrin and Sec7 domain containing 3
chr9_+_7272514 0.25 ENSMUST00000015394.10
matrix metallopeptidase 13
chr15_+_25774070 0.25 ENSMUST00000125667.3
myosin X
chr11_+_78237492 0.24 ENSMUST00000100755.4
unc-119 lipid binding chaperone
chr2_+_29968596 0.24 ENSMUST00000045246.8
protein kinase N3
chr5_-_108022900 0.24 ENSMUST00000138111.8
ENSMUST00000112642.8
ecotropic viral integration site 5
chr5_-_137784943 0.24 ENSMUST00000132726.2
methylphosphate capping enzyme
chrX_-_153999333 0.24 ENSMUST00000112551.4
spermidine/spermine N1-acetyl transferase 1
chr11_+_78403019 0.24 ENSMUST00000001127.11
polymerase (DNA-directed), delta interacting protein 2
chr5_+_147797258 0.24 ENSMUST00000031654.10
proteasome maturation protein
chr17_-_45903188 0.24 ENSMUST00000164769.8
solute carrier family 29 (nucleoside transporters), member 1
chr9_-_20085353 0.24 ENSMUST00000215984.3
olfactory receptor 870
chr11_-_120930193 0.23 ENSMUST00000026159.6
CD7 antigen
chrX_-_72974357 0.23 ENSMUST00000155597.2
ENSMUST00000114379.8
renin binding protein
chr1_+_58069090 0.23 ENSMUST00000001027.7
aldehyde oxidase 1
chr2_+_155617251 0.22 ENSMUST00000029141.6
matrix metallopeptidase 24
chr19_+_8906916 0.22 ENSMUST00000096241.6
echinoderm microtubule associated protein like 3
chr5_+_114268425 0.22 ENSMUST00000031587.13
uracil DNA glycosylase

Network of associatons between targets according to the STRING database.

First level regulatory network of Nfe2_Bach1_Mafk

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.5 GO:1903659 transforming growth factor beta activation(GO:0036363) regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.6 1.9 GO:2000469 negative regulation of peroxidase activity(GO:2000469)
0.4 1.6 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.4 1.9 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.4 1.5 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.4 3.3 GO:0035754 B cell chemotaxis(GO:0035754)
0.3 1.0 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.3 1.0 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.3 1.3 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
0.3 3.4 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.3 1.2 GO:0043418 homocysteine catabolic process(GO:0043418)
0.3 0.8 GO:0002344 peripheral B cell selection(GO:0002343) B cell affinity maturation(GO:0002344)
0.2 0.7 GO:1904437 negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) regulation of T cell antigen processing and presentation(GO:0002625) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440)
0.2 0.7 GO:0019064 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.2 0.6 GO:1902569 regulation of activation of JAK2 kinase activity(GO:0010534) activation of JAK2 kinase activity(GO:0042977) negative regulation of activation of JAK2 kinase activity(GO:1902569)
0.2 6.3 GO:0019430 removal of superoxide radicals(GO:0019430)
0.2 3.5 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.2 1.4 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.2 0.6 GO:1903233 regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233)
0.2 0.6 GO:0046021 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.2 1.0 GO:0051031 tRNA transport(GO:0051031)
0.2 0.8 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.2 0.9 GO:0051661 maintenance of centrosome location(GO:0051661)
0.1 2.5 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 0.4 GO:0060821 inactivation of X chromosome by DNA methylation(GO:0060821)
0.1 0.8 GO:0061621 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 0.5 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.1 0.6 GO:0060356 leucine import(GO:0060356)
0.1 0.8 GO:0015862 uridine transport(GO:0015862)
0.1 0.3 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.1 0.3 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.1 0.4 GO:0071449 response to lipid hydroperoxide(GO:0006982) cellular response to lipid hydroperoxide(GO:0071449)
0.1 0.4 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.1 0.9 GO:0042078 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1 0.4 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.1 0.3 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 1.8 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 0.4 GO:0090191 negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
0.1 0.4 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.1 0.2 GO:0006285 base-excision repair, AP site formation(GO:0006285)
0.1 1.8 GO:0048671 negative regulation of collateral sprouting(GO:0048671)
0.1 0.4 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.1 0.4 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.1 0.2 GO:0002436 immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265)
0.1 0.8 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.8 GO:0061635 regulation of protein complex stability(GO:0061635)
0.1 0.2 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.1 0.3 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
0.1 0.2 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.1 0.2 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.1 0.8 GO:0006241 CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036)
0.1 0.4 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.1 0.4 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.1 0.9 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 0.3 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.1 0.3 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.1 0.2 GO:0006624 vacuolar protein processing(GO:0006624)
0.0 0.2 GO:1904430 negative regulation of t-circle formation(GO:1904430)
0.0 0.2 GO:0032917 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.0 0.2 GO:0009115 xanthine catabolic process(GO:0009115)
0.0 0.6 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.0 0.3 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.4 GO:1905146 lysosomal protein catabolic process(GO:1905146)
0.0 0.9 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.8 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.4 GO:0061727 methylglyoxal metabolic process(GO:0009438) methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.6 GO:0007603 phototransduction, visible light(GO:0007603)
0.0 0.2 GO:0009992 cellular water homeostasis(GO:0009992)
0.0 0.9 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.0 1.0 GO:0045821 positive regulation of glycolytic process(GO:0045821)
0.0 0.6 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.4 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.3 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.0 0.3 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.0 0.1 GO:0036135 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.0 0.1 GO:2000660 negative regulation of chemokine biosynthetic process(GO:0045079) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.2 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.4 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.3 GO:0014010 Schwann cell proliferation(GO:0014010)
0.0 2.0 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.4 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 1.3 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.6 GO:2000269 regulation of fibroblast apoptotic process(GO:2000269)
0.0 0.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.1 GO:0035747 natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501)
0.0 0.6 GO:0043486 histone exchange(GO:0043486)
0.0 0.5 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.4 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.4 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.1 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.2 GO:0050961 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.4 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.0 1.1 GO:0006378 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.0 0.2 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.0 0.1 GO:0070256 positive regulation of nucleobase-containing compound transport(GO:0032241) regulation of nucleoside transport(GO:0032242) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
0.0 1.0 GO:0001702 gastrulation with mouth forming second(GO:0001702)
0.0 0.7 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 0.2 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0 0.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.6 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.1 GO:0040031 snRNA modification(GO:0040031)
0.0 1.3 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 2.1 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.1 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.4 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.0 GO:0015881 creatine transport(GO:0015881)
0.0 0.1 GO:0019346 homoserine metabolic process(GO:0009092) transsulfuration(GO:0019346) hydrogen sulfide biosynthetic process(GO:0070814)
0.0 0.4 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.0 0.1 GO:0060313 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313) negative regulation of neutrophil activation(GO:1902564)
0.0 0.2 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.0 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.0 0.7 GO:0030224 monocyte differentiation(GO:0030224)
0.0 0.8 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.7 GO:2000279 negative regulation of DNA biosynthetic process(GO:2000279)
0.0 0.2 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.2 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.3 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.0 0.0 GO:2001274 immunoglobulin biosynthetic process(GO:0002378) negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.0 0.1 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.0 0.4 GO:0071539 protein localization to centrosome(GO:0071539)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.5 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.7 3.5 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.4 4.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.3 4.0 GO:0031597 proteasome regulatory particle, base subcomplex(GO:0008540) cytosolic proteasome complex(GO:0031597)
0.2 0.6 GO:0044753 amphisome(GO:0044753)
0.2 0.4 GO:0031595 nuclear proteasome complex(GO:0031595)
0.2 0.6 GO:0014801 longitudinal sarcoplasmic reticulum(GO:0014801)
0.2 0.5 GO:0032545 CURI complex(GO:0032545) UTP-C complex(GO:0034456)
0.2 4.7 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 2.5 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 3.5 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 1.4 GO:0005838 proteasome regulatory particle(GO:0005838)
0.1 0.3 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.1 0.6 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 1.1 GO:0042382 paraspeckles(GO:0042382)
0.1 0.4 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.1 1.4 GO:0044754 autolysosome(GO:0044754)
0.1 0.9 GO:0000235 astral microtubule(GO:0000235)
0.1 1.6 GO:0031045 dense core granule(GO:0031045)
0.1 0.3 GO:1990589 Lewy body core(GO:1990037) ATF4-CREB1 transcription factor complex(GO:1990589) ATF1-ATF4 transcription factor complex(GO:1990590)
0.1 0.7 GO:1990357 terminal web(GO:1990357)
0.1 0.8 GO:0097451 glial limiting end-foot(GO:0097451)
0.1 0.9 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 0.4 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 0.4 GO:1990462 omegasome(GO:1990462)
0.1 0.5 GO:0045298 tubulin complex(GO:0045298)
0.1 0.8 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.1 0.4 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 0.2 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.4 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.4 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.9 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.7 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.2 GO:0044299 C-fiber(GO:0044299)
0.0 0.1 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 1.8 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.2 GO:0031523 Myb complex(GO:0031523)
0.0 0.8 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.7 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.5 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 2.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.2 GO:0042825 TAP complex(GO:0042825)
0.0 0.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.2 GO:0000243 commitment complex(GO:0000243)
0.0 0.2 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.8 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.1 GO:0045098 type III intermediate filament(GO:0045098)
0.0 0.3 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.5 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 1.1 GO:0044439 microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.0 0.2 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.6 GO:0008305 integrin complex(GO:0008305)
0.0 1.1 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.3 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.4 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.1 GO:0005839 proteasome core complex(GO:0005839)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.5 GO:0035730 S-nitrosoglutathione binding(GO:0035730) dinitrosyl-iron complex binding(GO:0035731)
0.8 3.3 GO:0047016 cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity(GO:0047016)
0.6 4.5 GO:0002135 CTP binding(GO:0002135)
0.4 3.3 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.4 3.5 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.3 2.5 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.3 4.6 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.3 1.2 GO:0003998 acylphosphatase activity(GO:0003998)
0.3 0.9 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.3 1.6 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.3 1.3 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.3 1.8 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.2 0.6 GO:0070540 stearic acid binding(GO:0070540)
0.2 1.0 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.2 0.8 GO:0004816 asparagine-tRNA ligase activity(GO:0004816)
0.2 0.8 GO:0003883 CTP synthase activity(GO:0003883)
0.2 1.3 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.2 0.7 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.2 4.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.4 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.1 0.4 GO:0038052 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.1 1.6 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 1.1 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.7 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 0.5 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 0.3 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.1 0.4 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.1 2.8 GO:0097602 cullin family protein binding(GO:0097602)
0.1 0.8 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 0.4 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.1 0.4 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.1 0.3 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 0.2 GO:0019809 spermidine binding(GO:0019809)
0.1 0.2 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.1 1.5 GO:0070628 proteasome binding(GO:0070628)
0.1 0.2 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.1 0.3 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.1 0.6 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 2.2 GO:0001968 fibronectin binding(GO:0001968)
0.1 1.6 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 0.7 GO:0039706 co-receptor binding(GO:0039706)
0.1 0.2 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0 0.3 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 1.6 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.4 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.1 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 0.0 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 0.1 GO:0016784 3-mercaptopyruvate sulfurtransferase activity(GO:0016784)
0.0 0.2 GO:0043546 xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726) molybdopterin cofactor binding(GO:0043546)
0.0 3.1 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.6 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 0.9 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.3 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.0 0.4 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.4 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.4 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.4 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.6 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.8 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 1.0 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.9 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.4 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.2 GO:0046978 TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.0 0.5 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.3 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.5 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.4 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.7 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 1.3 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.7 GO:0016209 antioxidant activity(GO:0016209)
0.0 0.1 GO:0034452 dynactin binding(GO:0034452)
0.0 1.2 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.4 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.0 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
0.0 0.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 1.2 GO:0051287 NAD binding(GO:0051287)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.0 1.1 GO:0005518 collagen binding(GO:0005518)
0.0 0.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.3 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.1 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.6 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.0 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.0 0.7 GO:0005158 insulin receptor binding(GO:0005158)
0.0 1.1 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.0 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 1.1 GO:0003725 double-stranded RNA binding(GO:0003725)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.2 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 2.3 PID AURORA B PATHWAY Aurora B signaling
0.0 1.9 PID IL1 PATHWAY IL1-mediated signaling events
0.0 3.9 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.6 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 1.7 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 4.5 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 2.0 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.8 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.5 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 1.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.9 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.4 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.9 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.2 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.5 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.8 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.4 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.4 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.2 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.9 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.8 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.1 PID CMYB PATHWAY C-MYB transcription factor network
0.0 2.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.9 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.2 3.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.2 10.2 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1 1.0 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 0.6 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 2.1 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 3.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 0.9 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 0.6 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.1 1.3 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 0.5 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 1.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.9 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 2.0 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 1.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.1 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.8 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.6 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.3 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.4 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.5 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.3 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.3 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.7 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.4 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.9 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.3 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 1.3 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.8 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.7 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 3.1 REACTOME TRANSLATION Genes involved in Translation
0.0 0.6 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 3.2 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.3 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.2 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation