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avrg: GFI1 WT vs 36n/n vs KD

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Results for Nfe2l2

Z-value: 1.96

Motif logo

Transcription factors associated with Nfe2l2

Gene Symbol Gene ID Gene Info
ENSMUSG00000015839.7 nuclear factor, erythroid derived 2, like 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nfe2l2mm39_v1_chr2_-_75534985_75535023-0.819.5e-02Click!

Activity profile of Nfe2l2 motif

Sorted Z-values of Nfe2l2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_36857202 1.65 ENSMUST00000165649.4
ENSMUST00000224769.2
growth hormone inducible transmembrane protein
chr17_-_45883421 1.50 ENSMUST00000130406.2
heat shock protein 90 alpha (cytosolic), class B member 1
chr4_+_116543045 1.29 ENSMUST00000129315.8
ENSMUST00000106470.8
peroxiredoxin 1
chr7_-_126398165 1.23 ENSMUST00000205890.2
ENSMUST00000205336.2
ENSMUST00000087566.11
aldolase A, fructose-bisphosphate
chr6_-_16898440 1.14 ENSMUST00000031533.11
transcription factor EC
chr19_-_4092218 1.12 ENSMUST00000237999.2
ENSMUST00000042700.12
glutathione S-transferase, pi 2
chr2_+_150412329 1.12 ENSMUST00000089200.3
cystatin F (leukocystatin)
chr11_-_74614654 1.08 ENSMUST00000102520.9
platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
chr12_+_71021395 1.07 ENSMUST00000160027.8
ENSMUST00000160864.8
proteasome subunit alpha 3
chr18_-_43610829 1.04 ENSMUST00000057110.11
eukaryotic translation initiation factor 3, subunit J2
chr14_-_36857083 1.01 ENSMUST00000042564.17
growth hormone inducible transmembrane protein
chr4_-_57956411 0.98 ENSMUST00000030051.6
thioredoxin 1
chr16_+_20470402 0.96 ENSMUST00000007212.9
ENSMUST00000232629.2
proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
chr4_-_126215462 0.96 ENSMUST00000102617.5
ADP-ribosylserine hydrolase
chr2_+_153491363 0.90 ENSMUST00000072997.10
ENSMUST00000109773.8
ENSMUST00000109774.9
ENSMUST00000081628.13
ENSMUST00000103151.8
ENSMUST00000056495.14
ENSMUST00000088976.12
ENSMUST00000109772.8
ENSMUST00000103150.10
DNA methyltransferase 3B
chr14_+_67953547 0.89 ENSMUST00000078053.13
potassium channel tetramerisation domain containing 9
chr7_-_113875261 0.82 ENSMUST00000135570.8
proteasome subunit alpha 1
chr7_-_80475722 0.80 ENSMUST00000205304.2
IQ motif containing GTPase activating protein 1
chr5_+_45677571 0.80 ENSMUST00000156481.8
ENSMUST00000119579.3
ENSMUST00000118833.3
mediator complex subunit 28
chr3_+_108164242 0.78 ENSMUST00000090569.10
proteasome subunit alpha 5
chr17_-_71305003 0.74 ENSMUST00000024846.13
ENSMUST00000232766.2
myosin, light chain 12A, regulatory, non-sarcomeric
chr2_+_151947444 0.72 ENSMUST00000041500.8
sulfiredoxin 1 homolog (S. cerevisiae)
chr19_-_4087907 0.71 ENSMUST00000237982.2
glutathione S-transferase, pi 1
chr11_+_120123727 0.71 ENSMUST00000122148.8
ENSMUST00000044985.14
BAH domain and coiled-coil containing 1
chr12_-_40298072 0.69 ENSMUST00000169926.8
interferon-related developmental regulator 1
chr5_+_137756407 0.67 ENSMUST00000141733.8
ENSMUST00000110985.2
TSC22 domain family, member 4
chrX_+_158155171 0.65 ENSMUST00000087143.7
eukaryotic translation initiation factor 1A, X-linked
chr12_+_55445560 0.65 ENSMUST00000021412.9
proteasome subunit alpha 6
chr4_+_116542741 0.65 ENSMUST00000135573.8
ENSMUST00000151129.8
peroxiredoxin 1
chr2_+_112092271 0.65 ENSMUST00000028553.4
NOP10 ribonucleoprotein
chr5_-_45607485 0.64 ENSMUST00000154962.8
ENSMUST00000118097.8
ENSMUST00000198258.5
quinoid dihydropteridine reductase
chr5_-_92496730 0.63 ENSMUST00000038816.13
ENSMUST00000118006.3
chemokine (C-X-C motif) ligand 10
chr5_-_45607463 0.63 ENSMUST00000197946.5
ENSMUST00000127562.3
quinoid dihydropteridine reductase
chr6_-_68713748 0.62 ENSMUST00000183936.2
ENSMUST00000196863.2
immunoglobulin kappa chain variable 19-93
chr19_-_8690330 0.62 ENSMUST00000206598.2
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
chr10_-_117215920 0.62 ENSMUST00000175924.2
cleavage and polyadenylation specific factor 6
chr12_-_85335193 0.59 ENSMUST00000121930.2
acylphosphatase 1, erythrocyte (common) type
chr14_+_67953687 0.58 ENSMUST00000150768.8
potassium channel tetramerisation domain containing 9
chr11_+_50101717 0.58 ENSMUST00000147468.8
mannoside acetylglucosaminyltransferase 4, isoenzyme B
chr18_-_35087355 0.57 ENSMUST00000025217.11
heat shock protein 9
chr11_-_59700820 0.55 ENSMUST00000047706.3
ENSMUST00000102697.10
folliculin
chr16_+_90017634 0.54 ENSMUST00000023707.11
superoxide dismutase 1, soluble
chr11_+_60428788 0.53 ENSMUST00000044250.4
alkB homolog 5, RNA demethylase
chr19_-_32080496 0.53 ENSMUST00000235213.2
ENSMUST00000236504.2
N-acylsphingosine amidohydrolase 2
chr5_-_45607554 0.52 ENSMUST00000015950.12
quinoid dihydropteridine reductase
chr12_-_83609217 0.51 ENSMUST00000222448.2
zinc finger, FYVE domain containing 1
chr12_+_111505253 0.51 ENSMUST00000220803.2
eukaryotic translation initiation factor 5
chr3_-_146487102 0.49 ENSMUST00000005164.12
protein kinase, cAMP dependent, catalytic, beta
chr10_+_17672004 0.48 ENSMUST00000037964.7
taxilin beta
chrX_+_73468140 0.48 ENSMUST00000135165.8
ENSMUST00000114128.8
ENSMUST00000004330.10
ENSMUST00000114133.9
ENSMUST00000114129.9
ENSMUST00000132749.2
inhibitor of kappaB kinase gamma
chr17_-_45884179 0.47 ENSMUST00000165127.8
ENSMUST00000166469.8
ENSMUST00000024739.14
heat shock protein 90 alpha (cytosolic), class B member 1
chr1_-_75195127 0.47 ENSMUST00000079464.13
tubulin, alpha 4A
chr1_+_135945798 0.47 ENSMUST00000117950.2
transmembrane protein 9
chr2_+_120439858 0.46 ENSMUST00000124187.8
HAUS augmin-like complex, subunit 2
chr5_+_100946493 0.46 ENSMUST00000016977.15
ENSMUST00000112898.8
ENSMUST00000112901.2
mitochondrial ribosomal protein S18C
chr1_+_135945705 0.46 ENSMUST00000063719.15
transmembrane protein 9
chr8_-_108315024 0.44 ENSMUST00000044106.6
proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
chr16_+_16962464 0.44 ENSMUST00000231726.2
YdjC homolog (bacterial)
chr9_-_21150350 0.44 ENSMUST00000049567.10
ENSMUST00000193982.2
kelch-like ECH-associated protein 1
chr7_-_113875342 0.43 ENSMUST00000033008.10
proteasome subunit alpha 1
chr11_+_78069477 0.43 ENSMUST00000092880.14
ENSMUST00000127587.8
TLC domain containing 1
chr14_-_20443676 0.43 ENSMUST00000061444.5
mitochondrial ribosomal protein S16
chr15_+_80139371 0.42 ENSMUST00000109605.5
ENSMUST00000229828.2
activating transcription factor 4
chr11_+_76836330 0.41 ENSMUST00000021197.10
bleomycin hydrolase
chr2_+_90884349 0.41 ENSMUST00000067663.14
ENSMUST00000002171.14
ENSMUST00000111441.10
proteasome (prosome, macropain) 26S subunit, ATPase 3
chr11_+_120564185 0.40 ENSMUST00000135346.8
ENSMUST00000127269.8
ENSMUST00000131727.9
ENSMUST00000149389.8
ENSMUST00000153346.8
alveolar soft part sarcoma chromosome region, candidate 1 (human)
chr11_+_76836545 0.40 ENSMUST00000125145.8
bleomycin hydrolase
chr15_-_79718423 0.40 ENSMUST00000109623.8
ENSMUST00000109625.8
ENSMUST00000023060.13
ENSMUST00000089299.6
chromobox 6
neuronal pentraxin chromo domain
chr5_-_138185438 0.39 ENSMUST00000110937.8
ENSMUST00000139276.2
ENSMUST00000048698.14
ENSMUST00000123415.8
TATA-box binding protein associated factor 6
chr7_+_127399789 0.39 ENSMUST00000125188.8
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr19_-_4889314 0.39 ENSMUST00000235245.2
ENSMUST00000037246.7
copper chaperone for superoxide dismutase
chr2_-_25162347 0.38 ENSMUST00000028342.7
SS nuclear autoantigen 1
chr9_-_21150523 0.37 ENSMUST00000194542.6
ENSMUST00000216436.2
kelch-like ECH-associated protein 1
chr7_+_127399776 0.36 ENSMUST00000046863.12
ENSMUST00000206674.2
ENSMUST00000106272.8
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr3_-_89867869 0.36 ENSMUST00000069805.14
ATPase, class I, type 8B, member 2
chrX_-_133483849 0.35 ENSMUST00000113213.2
ENSMUST00000033617.13
Bruton agammaglobulinemia tyrosine kinase
chr13_-_55677109 0.35 ENSMUST00000223563.2
docking protein 3
chr16_-_18161746 0.35 ENSMUST00000231372.2
ENSMUST00000130752.2
ENSMUST00000231605.2
ENSMUST00000115628.10
transport and golgi organization 2
chr12_+_111505216 0.34 ENSMUST00000050993.11
eukaryotic translation initiation factor 5
chr2_+_90884612 0.34 ENSMUST00000185715.7
proteasome (prosome, macropain) 26S subunit, ATPase 3
chr5_-_21990170 0.34 ENSMUST00000115193.8
ENSMUST00000115192.2
ENSMUST00000115195.8
ENSMUST00000030771.12
DnaJ heat shock protein family (Hsp40) member C2
chr7_-_30810422 0.34 ENSMUST00000039435.15
hepsin
chr2_-_120439981 0.33 ENSMUST00000133612.2
ENSMUST00000102498.8
ENSMUST00000102499.8
leucine rich repeat containing 57
chr2_-_166885414 0.33 ENSMUST00000067584.7
zinc finger, NFX1-type containing 1
chr7_+_140438468 0.33 ENSMUST00000209766.2
RIC8 guanine nucleotide exchange factor A
chr1_+_85992341 0.33 ENSMUST00000027432.9
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
chr11_-_55075855 0.33 ENSMUST00000039305.6
solute carrier family 36 (proton/amino acid symporter), member 2
chr1_-_155022501 0.31 ENSMUST00000027744.10
major histocompatibility complex, class I-related
chr8_+_95710977 0.31 ENSMUST00000093271.8
adhesion G protein-coupled receptor G1
chr1_+_157353696 0.28 ENSMUST00000111700.8
SEC16 homolog B (S. cerevisiae)
chr11_-_30599510 0.28 ENSMUST00000074613.4
acylphosphatase 2, muscle type
chr8_+_106052970 0.28 ENSMUST00000015000.12
ENSMUST00000098453.9
transmembrane protein 208
chr2_+_164790139 0.27 ENSMUST00000017881.3
matrix metallopeptidase 9
chr19_-_4889284 0.27 ENSMUST00000236451.2
ENSMUST00000236178.2
copper chaperone for superoxide dismutase
chr19_-_4087940 0.27 ENSMUST00000237893.2
ENSMUST00000169613.4
glutathione S-transferase, pi 1
chr16_+_20367327 0.26 ENSMUST00000003319.6
ENSMUST00000232680.2
ENSMUST00000232490.2
ATP-binding cassette, sub-family F (GCN20), member 3
chrX_-_37341274 0.26 ENSMUST00000089056.10
ENSMUST00000089054.11
ENSMUST00000066498.8
transmembrane protein 255A
chr3_+_28859585 0.26 ENSMUST00000043867.11
ENSMUST00000194649.2
ribosomal protein L22 like 1
chr6_+_48818567 0.26 ENSMUST00000203639.3
transmembrane protein 176A
chr12_+_111504450 0.25 ENSMUST00000166123.9
ENSMUST00000222441.2
eukaryotic translation initiation factor 5
chr10_+_127894816 0.25 ENSMUST00000052798.14
prostaglandin E synthase 3
chr14_+_67953584 0.24 ENSMUST00000145542.8
ENSMUST00000125212.2
potassium channel tetramerisation domain containing 9
chr9_-_44162762 0.24 ENSMUST00000034618.6
PDZ domain containing 3
chr16_-_50151350 0.24 ENSMUST00000114488.8
bobby sox HMG box containing
chr5_-_138185686 0.24 ENSMUST00000110936.8
TATA-box binding protein associated factor 6
chr7_+_127511681 0.24 ENSMUST00000033070.9
K(lysine) acetyltransferase 8
chr7_+_127400016 0.24 ENSMUST00000106271.2
ENSMUST00000138432.2
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr9_-_21150100 0.24 ENSMUST00000164812.8
kelch-like ECH-associated protein 1
chr14_-_55950545 0.23 ENSMUST00000002389.9
ENSMUST00000226907.2
transglutaminase 1, K polypeptide
chr1_+_165596961 0.23 ENSMUST00000040298.5
cellular repressor of E1A-stimulated genes 1
chr2_+_25162487 0.23 ENSMUST00000028341.11
anaphase promoting complex subunit 2
chr7_+_101875019 0.23 ENSMUST00000142873.8
post-GPI attachment to proteins 2
chr2_+_155617251 0.22 ENSMUST00000029141.6
matrix metallopeptidase 24
chr10_+_115979787 0.22 ENSMUST00000105271.9
protein tyrosine phosphatase, receptor type, R
chr4_-_109333866 0.21 ENSMUST00000030284.10
ring finger protein 11
chr15_+_78294154 0.21 ENSMUST00000229739.2
mercaptopyruvate sulfurtransferase
chr7_+_127160751 0.21 ENSMUST00000190278.3
transmembrane protein 265
chr11_-_120930193 0.20 ENSMUST00000026159.6
CD7 antigen
chr7_-_104002534 0.20 ENSMUST00000130139.3
ENSMUST00000059037.15
tripartite motif-containing 12C
chr4_+_102278715 0.20 ENSMUST00000106904.9
phosphodiesterase 4B, cAMP specific
chr2_-_120439764 0.20 ENSMUST00000102496.8
leucine rich repeat containing 57
chr7_+_127728712 0.19 ENSMUST00000033053.8
ENSMUST00000205460.2
integrin alpha X
chr2_-_120439826 0.19 ENSMUST00000102497.10
leucine rich repeat containing 57
chr5_+_20112500 0.19 ENSMUST00000101558.10
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr11_+_97253221 0.19 ENSMUST00000238729.2
ENSMUST00000045540.4
suppressor of cytokine signaling 7
chrX_-_165992145 0.19 ENSMUST00000112176.8
thymosin, beta 4, X chromosome
chr11_-_50216426 0.19 ENSMUST00000179865.8
ENSMUST00000020637.9
calnexin
chr18_+_35731735 0.18 ENSMUST00000236868.2
polyadenylate-binding protein-interacting protein 2
chr11_+_3845221 0.17 ENSMUST00000109996.8
ENSMUST00000055931.5
dual specificity phosphatase 18
chr4_-_140501507 0.17 ENSMUST00000026381.7
peptidyl arginine deiminase, type IV
chrX_+_163052367 0.17 ENSMUST00000145412.8
ENSMUST00000033749.9
pirin
chr13_-_23894828 0.16 ENSMUST00000091706.14
homeostatic iron regulator
chr7_+_18915136 0.16 ENSMUST00000144054.8
ENSMUST00000141718.8
echinoderm microtubule associated protein like 2
chr11_-_120520954 0.15 ENSMUST00000106180.2
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
chr2_+_11710246 0.15 ENSMUST00000148748.8
interleukin 15 receptor, alpha chain
chr10_+_127894843 0.15 ENSMUST00000084771.3
prostaglandin E synthase 3
chr12_+_111504640 0.15 ENSMUST00000222375.2
ENSMUST00000222388.2
eukaryotic translation initiation factor 5
chr11_-_120521382 0.15 ENSMUST00000106181.8
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
chr9_+_108566513 0.15 ENSMUST00000192344.2
protein kinase, cAMP dependent regulatory, type II alpha
chr4_-_133601990 0.14 ENSMUST00000168974.9
ribosomal protein S6 kinase polypeptide 1
chr4_+_12140263 0.14 ENSMUST00000050069.9
ENSMUST00000069128.8
RNA binding motif protein 12 B1
chr13_+_49735938 0.14 ENSMUST00000221170.2
osteomodulin
chr11_+_107370375 0.14 ENSMUST00000106750.5
proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
chr5_+_138185747 0.13 ENSMUST00000110934.9
canopy FGF signaling regulator 4
chr19_+_8906916 0.13 ENSMUST00000096241.6
echinoderm microtubule associated protein like 3
chr11_+_107370303 0.13 ENSMUST00000021063.13
ENSMUST00000106752.10
proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
chr12_-_17050332 0.13 ENSMUST00000134938.8
ENSMUST00000137960.2
PQ loop repeat containing
chr5_-_100946334 0.12 ENSMUST00000133845.8
helicase, POLQ-like
chr7_+_18915086 0.12 ENSMUST00000120595.8
ENSMUST00000048502.10
echinoderm microtubule associated protein like 2
chr9_+_32135540 0.12 ENSMUST00000168954.9
Rho GTPase activating protein 32
chr5_-_100946434 0.11 ENSMUST00000044684.14
helicase, POLQ-like
chr8_+_70275079 0.11 ENSMUST00000164890.8
ENSMUST00000034325.6
ENSMUST00000238452.2
lysophosphatidic acid receptor 2
chr5_-_112400375 0.11 ENSMUST00000112385.8
crystallin, beta A4
chr1_-_121260298 0.11 ENSMUST00000071064.13
insulin induced gene 2
chr6_+_117988399 0.10 ENSMUST00000164960.4
RasGEF domain family, member 1A
chr11_+_69523754 0.10 ENSMUST00000018909.4
fragile X mental retardation, autosomal homolog 2
chr12_+_16860931 0.10 ENSMUST00000020908.9
E2F transcription factor 6
chr14_-_122035225 0.10 ENSMUST00000100299.11
dedicator of cytokinesis 9
chr9_-_20085353 0.10 ENSMUST00000215984.3
olfactory receptor 870
chr2_+_166647426 0.10 ENSMUST00000099078.10
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr7_+_127399848 0.10 ENSMUST00000139068.8
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr11_-_50101592 0.09 ENSMUST00000143379.2
ENSMUST00000015981.12
ENSMUST00000102774.11
sequestosome 1
chr7_+_45289391 0.09 ENSMUST00000148532.4
MEF2 activating motif and SAP domain containing transcriptional regulator
chr7_-_44646645 0.09 ENSMUST00000207342.2
BCL2-like 12 (proline rich)
chr11_-_69696428 0.08 ENSMUST00000051025.5
transmembrane protein 102
chr18_-_3281089 0.08 ENSMUST00000139537.2
ENSMUST00000124747.8
cAMP responsive element modulator
chr1_+_58069090 0.08 ENSMUST00000001027.7
aldehyde oxidase 1
chr4_-_118667141 0.07 ENSMUST00000084313.5
ENSMUST00000219094.2
olfactory receptor 1335
chr11_-_120328458 0.07 ENSMUST00000044271.15
ENSMUST00000103017.4
NPL4 homolog, ubiquitin recognition factor
chr18_-_39652468 0.07 ENSMUST00000237944.2
nuclear receptor subfamily 3, group C, member 1
chr16_-_16962256 0.06 ENSMUST00000115711.10
coiled-coil domain containing 116
chr4_+_101365144 0.06 ENSMUST00000149047.8
ENSMUST00000106929.10
DnaJ heat shock protein family (Hsp40) member C6
chr10_+_75404482 0.06 ENSMUST00000134503.8
ENSMUST00000125770.8
ENSMUST00000128886.8
ENSMUST00000151212.8
gamma-glutamyltransferase 1
chr7_+_44498415 0.06 ENSMUST00000107885.8
AKT1 substrate 1 (proline-rich)
chr1_-_120001752 0.06 ENSMUST00000056089.8
transmembrane protein 37
chr19_+_8816663 0.06 ENSMUST00000160556.8
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr9_+_65121944 0.05 ENSMUST00000069000.9
poly (ADP-ribose) polymerase family, member 16
chr17_-_43003135 0.05 ENSMUST00000170723.8
ENSMUST00000164524.2
ENSMUST00000024711.11
ENSMUST00000167993.8
adhesion G protein-coupled receptor F4
chr4_+_117109204 0.05 ENSMUST00000125943.8
ENSMUST00000106434.8
transmembrane protein 53
chr2_-_44817173 0.05 ENSMUST00000130991.8
glycosyltransferase-like domain containing 1
chr5_+_20112704 0.05 ENSMUST00000115267.7
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr3_-_141687987 0.05 ENSMUST00000029948.15
bone morphogenetic protein receptor, type 1B
chr5_+_30218112 0.05 ENSMUST00000026845.12
ENSMUST00000199183.5
ENSMUST00000195978.5
interleukin 6
chr18_-_3280999 0.04 ENSMUST00000049942.13
cAMP responsive element modulator
chr7_+_108312527 0.04 ENSMUST00000209620.4
ENSMUST00000074730.4
olfactory receptor 512
chr11_+_4207557 0.04 ENSMUST00000066283.12
leukemia inhibitory factor
chr18_+_35731658 0.04 ENSMUST00000041314.17
ENSMUST00000236666.2
ENSMUST00000236020.2
ENSMUST00000235400.2
polyadenylate-binding protein-interacting protein 2
chr16_-_32688640 0.04 ENSMUST00000089684.10
ENSMUST00000040986.15
ENSMUST00000115105.9
RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein
chr12_-_113760187 0.04 ENSMUST00000192911.2
ENSMUST00000103455.3
immunoglobulin heavy variable 2-6-8
chr14_-_52257452 0.03 ENSMUST00000228162.2
zinc finger protein 219
chr14_+_53921052 0.03 ENSMUST00000103663.6
T cell receptor alpha variable 4-4-DV10
chr18_+_20380397 0.03 ENSMUST00000054128.7
desmoglein 1 gamma
chr3_-_144514386 0.03 ENSMUST00000197013.2
chloride channel accessory 3A2
chr9_-_44437694 0.03 ENSMUST00000062215.8
chemokine (C-X-C motif) receptor 5
chr12_-_113649535 0.03 ENSMUST00000103449.4
ENSMUST00000195707.3
immunoglobulin heavy variable 2-5
chr4_+_130297132 0.03 ENSMUST00000105993.4
Na+/K+ transporting ATPase interacting 1
chr17_+_37756371 0.03 ENSMUST00000078207.4
ENSMUST00000218675.2
olfactory receptor 108
chr19_-_8906686 0.03 ENSMUST00000096242.5
rod outer segment membrane protein 1
chrX_-_35755483 0.03 ENSMUST00000169499.2
predicted gene 14569
chr11_+_78068931 0.03 ENSMUST00000147819.8
TLC domain containing 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Nfe2l2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:1903660 transforming growth factor beta activation(GO:0036363) regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.3 1.0 GO:2000469 negative regulation of peroxidase activity(GO:2000469)
0.3 0.9 GO:0060821 inactivation of X chromosome by DNA methylation(GO:0060821)
0.2 0.8 GO:0043418 homocysteine catabolic process(GO:0043418)
0.2 0.6 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.2 0.6 GO:1901874 negative regulation of cellular respiration(GO:1901856) regulation of post-translational protein modification(GO:1901873) negative regulation of post-translational protein modification(GO:1901874)
0.2 1.1 GO:0051661 maintenance of centrosome location(GO:0051661)
0.2 1.8 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
0.2 1.0 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.2 0.6 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
0.1 0.4 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.1 0.6 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.1 0.6 GO:0060356 leucine import(GO:0060356)
0.1 1.1 GO:0035754 B cell chemotaxis(GO:0035754)
0.1 0.4 GO:0002343 peripheral B cell selection(GO:0002343) B cell affinity maturation(GO:0002344)
0.1 0.3 GO:0034769 basement membrane disassembly(GO:0034769)
0.1 0.4 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.1 0.3 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.1 0.5 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.1 1.0 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.1 2.5 GO:0019430 removal of superoxide radicals(GO:0019430)
0.1 0.3 GO:0036233 proline transmembrane transport(GO:0035524) glycine import(GO:0036233)
0.1 1.3 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 0.3 GO:0006624 vacuolar protein processing(GO:0006624)
0.1 0.7 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 1.2 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1 0.8 GO:1900086 positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
0.1 0.2 GO:1904440 negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) regulation of T cell antigen processing and presentation(GO:0002625) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440)
0.0 0.8 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.3 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.5 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.7 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.2 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.8 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.2 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.6 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.7 GO:0048671 negative regulation of collateral sprouting(GO:0048671)
0.0 0.4 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.3 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0 0.2 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.0 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.3 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0 0.2 GO:0070814 homoserine metabolic process(GO:0009092) transsulfuration(GO:0019346) hydrogen sulfide biosynthetic process(GO:0070814)
0.0 0.5 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.3 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.0 0.2 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 1.1 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.3 GO:0070586 cell-cell adhesion involved in gastrulation(GO:0070586)
0.0 0.0 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.2 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.1 GO:0009115 xanthine catabolic process(GO:0009115)
0.0 0.1 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.0 0.7 GO:0006801 superoxide metabolic process(GO:0006801)
0.0 0.2 GO:0050961 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.9 GO:0032543 mitochondrial translation(GO:0032543)
0.0 1.0 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.2 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.4 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.6 GO:0006378 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.0 0.1 GO:0072318 clathrin coat disassembly(GO:0072318)
0.0 0.2 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.1 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.4 2.0 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.3 3.8 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.2 0.6 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.2 2.0 GO:0031597 proteasome regulatory particle, base subcomplex(GO:0008540) cytosolic proteasome complex(GO:0031597)
0.1 0.3 GO:0031595 nuclear proteasome complex(GO:0031595)
0.1 1.1 GO:0000235 astral microtubule(GO:0000235)
0.1 0.4 GO:1990037 Lewy body core(GO:1990037) ATF4-CREB1 transcription factor complex(GO:1990589) ATF1-ATF4 transcription factor complex(GO:1990590)
0.1 0.5 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.1 1.9 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 0.6 GO:0042382 paraspeckles(GO:0042382)
0.1 0.6 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 1.0 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 0.5 GO:0070652 HAUS complex(GO:0070652)
0.0 0.2 GO:1990462 omegasome(GO:1990462)
0.0 0.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0044753 amphisome(GO:0044753)
0.0 0.2 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.5 GO:0031045 dense core granule(GO:0031045)
0.0 0.6 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.9 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.1 GO:0005879 axonemal microtubule(GO:0005879) symmetric synapse(GO:0032280)
0.0 0.7 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.3 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.2 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.7 GO:0016460 myosin II complex(GO:0016460)
0.0 0.2 GO:1990357 terminal web(GO:1990357)
0.0 0.8 GO:0016592 mediator complex(GO:0016592)
0.0 0.4 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.2 GO:0097451 glial limiting end-foot(GO:0097451)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.3 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.2 GO:1904949 ATPase complex(GO:1904949)
0.0 2.4 GO:0030496 midbody(GO:0030496)
0.0 0.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.9 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.6 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0035731 S-nitrosoglutathione binding(GO:0035730) dinitrosyl-iron complex binding(GO:0035731)
0.6 1.8 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155)
0.3 2.0 GO:0002135 CTP binding(GO:0002135)
0.3 1.1 GO:0047016 cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity(GO:0047016)
0.2 0.9 GO:0003998 acylphosphatase activity(GO:0003998)
0.2 1.2 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.2 1.3 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 3.8 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 1.9 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 0.6 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.3 GO:0005302 L-tyrosine transmembrane transporter activity(GO:0005302)
0.1 0.8 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 0.4 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.1 0.7 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.7 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.1 0.6 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 0.5 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.1 0.9 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.2 GO:0016784 3-mercaptopyruvate sulfurtransferase activity(GO:0016784)
0.1 0.3 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 0.7 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.5 GO:0017040 ceramidase activity(GO:0017040)
0.1 1.5 GO:0097602 cullin family protein binding(GO:0097602)
0.1 0.6 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.6 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.5 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.2 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.0 0.8 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.2 GO:0030249 guanylate cyclase regulator activity(GO:0030249)
0.0 0.2 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.3 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 1.1 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.4 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 1.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.6 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.3 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.2 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0016726 aldehyde oxidase activity(GO:0004031) xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726) molybdopterin cofactor binding(GO:0043546)
0.0 0.6 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.8 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.2 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.1 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.2 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.7 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors(GO:0016667)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.6 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.1 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.9 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 2.3 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 1.1 PID AURORA B PATHWAY Aurora B signaling
0.0 0.5 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.8 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.6 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 1.6 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.5 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.1 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 6.1 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1 1.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.4 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.5 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 2.4 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 1.1 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.6 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.6 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.9 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.6 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.9 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.6 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.2 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.6 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.1 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.1 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.6 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex