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avrg: GFI1 WT vs 36n/n vs KD

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Results for Nfix

Z-value: 2.73

Motif logo

Transcription factors associated with Nfix

Gene Symbol Gene ID Gene Info
ENSMUSG00000001911.17 nuclear factor I/X

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nfixmm39_v1_chr8_-_85526972_855270080.983.2e-03Click!

Activity profile of Nfix motif

Sorted Z-values of Nfix motif

Promoter Log-likelihood Transcript Gene Gene Info
chr13_-_23806530 5.98 ENSMUST00000062045.4
H1.4 linker histone, cluster member
chr11_+_68986043 4.07 ENSMUST00000101004.9
period circadian clock 1
chr1_-_44258112 3.76 ENSMUST00000054801.4
methyltransferase like 21E
chr17_-_82045800 3.43 ENSMUST00000235015.2
ENSMUST00000163123.3
solute carrier family 8 (sodium/calcium exchanger), member 1
chr18_-_78166595 2.64 ENSMUST00000091813.12
solute carrier family 14 (urea transporter), member 1
chr19_+_8828132 2.46 ENSMUST00000235683.2
ENSMUST00000096257.3
LRRN4 C-terminal like
chr5_-_84565218 2.13 ENSMUST00000113401.4
Eph receptor A5
chr7_+_26895206 2.07 ENSMUST00000179391.8
ENSMUST00000108379.8
cDNA sequence BC024978
chr12_-_45120895 1.83 ENSMUST00000120531.8
ENSMUST00000143376.8
syntaxin binding protein 6 (amisyn)
chr1_+_107456731 1.74 ENSMUST00000182198.8
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 10
chr3_-_129834788 1.61 ENSMUST00000168644.3
Sec24 related gene family, member B (S. cerevisiae)
chr7_+_19699291 1.58 ENSMUST00000094753.6
carcinoembryonic antigen-related cell adhesion molecule 20
chr9_+_89791943 1.58 ENSMUST00000189545.2
ENSMUST00000034909.11
ENSMUST00000034912.6
RAS protein-specific guanine nucleotide-releasing factor 1
chr15_-_98769056 1.54 ENSMUST00000178486.9
ENSMUST00000023741.16
lysine (K)-specific methyltransferase 2D
chr16_+_65317389 1.53 ENSMUST00000176330.8
ENSMUST00000004964.15
ENSMUST00000176038.8
POU domain, class 1, transcription factor 1
chr7_+_142030744 1.51 ENSMUST00000149521.8
lymphocyte specific 1
chr5_+_64969679 1.46 ENSMUST00000166409.6
ENSMUST00000197879.2
Kruppel-like factor 3 (basic)
chr12_-_72455708 1.41 ENSMUST00000078505.14
reticulon 1
chr9_-_87613301 1.34 ENSMUST00000034991.8
T-box18
chr6_-_128332760 1.28 ENSMUST00000133134.3
ENSMUST00000157005.3
tubby-like protein 3
chr7_+_46700349 1.26 ENSMUST00000010451.8
transmembrane protein 86A
chr3_-_58792633 1.25 ENSMUST00000055636.13
ENSMUST00000072551.7
ENSMUST00000051408.8
clarin 1
chr1_+_159351337 1.21 ENSMUST00000192069.6
tenascin R
chr1_-_160134873 1.19 ENSMUST00000193185.6
RAB GTPase activating protein 1-like
chr11_+_96822213 1.19 ENSMUST00000107633.2
proline rich 15-like
chr3_+_63203235 1.15 ENSMUST00000194134.6
membrane metallo endopeptidase
chr10_-_12744025 1.13 ENSMUST00000219660.2
utrophin
chr5_-_104125226 1.12 ENSMUST00000048118.15
hydroxysteroid (17-beta) dehydrogenase 13
chrX_+_162691978 1.11 ENSMUST00000069041.15
adaptor-related protein complex 1, sigma 2 subunit
chr2_-_111843053 1.08 ENSMUST00000213559.3
olfactory receptor 1310
chr16_+_51851917 1.06 ENSMUST00000227062.2
Casitas B-lineage lymphoma b
chr7_-_19621833 1.05 ENSMUST00000052605.8
carcinoembryonic antigen-related cell adhesion molecule 19
chr10_-_12743915 1.04 ENSMUST00000219584.2
utrophin
chr1_-_162687488 1.03 ENSMUST00000134098.8
ENSMUST00000111518.3
flavin containing monooxygenase 1
chr16_+_51851588 1.03 ENSMUST00000114471.3
Casitas B-lineage lymphoma b
chr11_+_77107006 0.99 ENSMUST00000156488.8
ENSMUST00000037912.12
slingshot protein phosphatase 2
chr16_+_57173456 0.94 ENSMUST00000159816.8
filamin A interacting protein 1-like
chr7_+_27879650 0.93 ENSMUST00000172467.8
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr11_+_98727611 0.93 ENSMUST00000107479.3
Rap guanine nucleotide exchange factor (GEF)-like 1
chr8_-_106723026 0.92 ENSMUST00000227363.2
ENSMUST00000081998.13
dipeptidase 2
chr4_+_118818775 0.90 ENSMUST00000058651.5
L-amino acid oxidase 1
chr2_+_121978156 0.89 ENSMUST00000102476.5
beta-2 microglobulin
chrX_+_10351360 0.88 ENSMUST00000076354.13
ENSMUST00000115526.2
tetraspanin 7
chr12_-_84408576 0.87 ENSMUST00000021659.2
ENSMUST00000065536.9
family with sequence similarity 161, member B
chr10_+_73657689 0.85 ENSMUST00000064562.14
ENSMUST00000193174.6
ENSMUST00000105426.10
ENSMUST00000129404.9
ENSMUST00000131321.9
ENSMUST00000126920.9
ENSMUST00000147189.9
ENSMUST00000105424.10
ENSMUST00000092420.13
ENSMUST00000105429.10
ENSMUST00000193361.6
ENSMUST00000131724.9
ENSMUST00000152655.9
ENSMUST00000151116.9
ENSMUST00000155701.9
ENSMUST00000152819.9
ENSMUST00000125517.9
ENSMUST00000124046.8
ENSMUST00000146682.8
ENSMUST00000177107.8
ENSMUST00000149977.9
ENSMUST00000191854.6
protocadherin 15
chrX_-_20816841 0.85 ENSMUST00000009550.14
ELK1, member of ETS oncogene family
chr12_-_72283465 0.84 ENSMUST00000021497.16
ENSMUST00000137990.2
reticulon 1
chr2_-_45003270 0.81 ENSMUST00000202935.4
ENSMUST00000068415.11
ENSMUST00000127520.8
zinc finger E-box binding homeobox 2
chr19_+_44321531 0.80 ENSMUST00000058856.9
stearoyl-coenzyme A desaturase 4
chr2_-_5680801 0.79 ENSMUST00000114987.4
calcium/calmodulin-dependent protein kinase ID
chrX_+_162692126 0.77 ENSMUST00000033734.14
ENSMUST00000112294.9
adaptor-related protein complex 1, sigma 2 subunit
chr2_+_165834546 0.77 ENSMUST00000109252.8
ENSMUST00000088095.6
nuclear receptor coactivator 3
chr7_-_26895561 0.75 ENSMUST00000122202.8
ENSMUST00000080356.10
small nuclear ribonucleoprotein polypeptide A
chrX_-_47297436 0.74 ENSMUST00000037960.11
zinc finger, DHHC domain containing 9
chr10_-_12702674 0.74 ENSMUST00000219130.2
utrophin
chr13_+_16186410 0.73 ENSMUST00000042603.14
inhibin beta-A
chr13_+_49761506 0.71 ENSMUST00000021822.7
osteoglycin
chr7_-_30251680 0.70 ENSMUST00000215288.2
ENSMUST00000108165.8
ENSMUST00000153594.3
proline and serine rich 3
chr8_+_91554933 0.69 ENSMUST00000048665.8
chromodomain helicase DNA binding protein 9
chr1_-_86039692 0.67 ENSMUST00000027431.7
5-hydroxytryptamine (serotonin) receptor 2B
chr5_-_123887434 0.66 ENSMUST00000182955.8
ENSMUST00000182489.8
ENSMUST00000183147.9
ENSMUST00000050827.14
ENSMUST00000057795.12
ENSMUST00000111515.8
ENSMUST00000182309.8
arginine/serine-rich coiled-coil 2
chr7_+_99184858 0.65 ENSMUST00000032995.15
ENSMUST00000162404.8
arrestin, beta 1
chr1_+_59952131 0.64 ENSMUST00000036540.12
family with sequence similarity 117, member B
chr11_+_3438274 0.64 ENSMUST00000064265.13
phospholipase A2, group III
chr11_+_115802828 0.62 ENSMUST00000132961.2
small integral membrane protein 6
chr16_+_20492014 0.60 ENSMUST00000154950.8
ENSMUST00000115461.8
ENSMUST00000136713.5
eukaryotic translation initiation factor 4, gamma 1
chr8_+_107409765 0.60 ENSMUST00000211979.2
transport and golgi organization 6
chr5_+_149335214 0.60 ENSMUST00000093110.12
mesenteric estrogen dependent adipogenesis
chr14_-_55150547 0.60 ENSMUST00000228495.3
ENSMUST00000228119.3
ENSMUST00000050772.10
ENSMUST00000231305.2
solute carrier family 22 (organic cation transporter), member 17
chrX_+_56008685 0.59 ENSMUST00000096431.10
adhesion G protein-coupled receptor G4
chr9_+_77959206 0.58 ENSMUST00000024104.9
glial cells missing homolog 1
chr6_-_128332789 0.57 ENSMUST00000001562.9
tubby-like protein 3
chr7_-_25358406 0.57 ENSMUST00000071329.8
branched chain ketoacid dehydrogenase E1, alpha polypeptide
chr5_+_104447037 0.55 ENSMUST00000031246.9
integrin binding sialoprotein
chr6_-_129428869 0.55 ENSMUST00000203162.3
C-type lectin domain family 1, member a
chr1_-_155293141 0.54 ENSMUST00000111775.8
ENSMUST00000111774.2
xenotropic and polytropic retrovirus receptor 1
chrX_-_47297746 0.52 ENSMUST00000088935.4
zinc finger, DHHC domain containing 9
chr8_-_103512274 0.50 ENSMUST00000075190.5
cadherin 11
chr16_-_20245071 0.47 ENSMUST00000115547.9
ENSMUST00000096199.5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr13_+_83720457 0.47 ENSMUST00000196730.5
myocyte enhancer factor 2C
chr18_+_34380738 0.47 ENSMUST00000066133.7
APC, WNT signaling pathway regulator
chr7_-_26895141 0.46 ENSMUST00000163311.9
ENSMUST00000126211.2
small nuclear ribonucleoprotein polypeptide A
chrX_+_103526380 0.45 ENSMUST00000087867.6
uracil phosphoribosyltransferase
chr2_+_29236815 0.45 ENSMUST00000028139.11
ENSMUST00000113830.11
mediator complex subunit 27
chr14_-_36628263 0.45 ENSMUST00000183007.2
coiled-coil serine rich 2
chr17_+_75772475 0.44 ENSMUST00000095204.6
RAS, guanyl releasing protein 3
chr13_+_83720484 0.43 ENSMUST00000196207.5
myocyte enhancer factor 2C
chr1_-_160079007 0.43 ENSMUST00000191909.6
RAB GTPase activating protein 1-like
chr8_-_37200051 0.42 ENSMUST00000098826.10
deleted in liver cancer 1
chr6_+_83055321 0.41 ENSMUST00000165164.9
ENSMUST00000092614.9
polycomb group ring finger 1
chr8_-_32440071 0.41 ENSMUST00000207678.3
neuregulin 1
chr16_+_27208660 0.41 ENSMUST00000143823.2
coiled-coil domain containing 50
chr7_+_141276575 0.41 ENSMUST00000185406.8
mucin 2
chr5_+_24618380 0.41 ENSMUST00000049346.10
acid-sensing (proton-gated) ion channel 3
chr16_-_3726503 0.40 ENSMUST00000115859.8
RIKEN cDNA 1700037C18 gene
chr16_-_20245138 0.39 ENSMUST00000079158.13
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr16_+_42727926 0.38 ENSMUST00000151244.8
ENSMUST00000114694.9
zinc finger and BTB domain containing 20
chr4_+_105014536 0.38 ENSMUST00000064139.8
phospholipid phosphatase 3
chr9_-_60418286 0.35 ENSMUST00000098660.10
thrombospondin, type I, domain containing 4
chr1_-_192880260 0.35 ENSMUST00000161367.2
TRAF3 interacting protein 3
chr17_+_84933872 0.34 ENSMUST00000025101.10
dynein cytoplasmic 2 light intermediate chain 1
chr18_-_78166539 0.34 ENSMUST00000160292.8
solute carrier family 14 (urea transporter), member 1
chr6_-_33037107 0.34 ENSMUST00000115091.2
ENSMUST00000127666.8
coiled-coil-helix-coiled-coil-helix domain containing 3
chr11_+_78181667 0.33 ENSMUST00000046361.5
ENSMUST00000238934.2
ribosomal protein S6 kinase related
chr16_+_20492564 0.33 ENSMUST00000141034.8
eukaryotic translation initiation factor 4, gamma 1
chr13_+_38529062 0.32 ENSMUST00000171970.3
bone morphogenetic protein 6
chr17_-_49871291 0.32 ENSMUST00000224595.2
ENSMUST00000057610.8
dishevelled associated activator of morphogenesis 2
chr10_-_125164826 0.30 ENSMUST00000211781.2
solute carrier family 16 (monocarboxylic acid transporters), member 7
chr17_+_35354430 0.30 ENSMUST00000173535.8
ENSMUST00000173952.8
BCL2-associated athanogene 6
chr5_+_117271632 0.30 ENSMUST00000179276.8
ENSMUST00000092889.12
ENSMUST00000145640.8
TAO kinase 3
chr2_-_25471703 0.29 ENSMUST00000114217.3
ENSMUST00000191602.2
apical junction component 1
chr11_+_67090878 0.29 ENSMUST00000124516.8
ENSMUST00000018637.15
ENSMUST00000129018.8
myosin, heavy polypeptide 1, skeletal muscle, adult
chr11_-_75329726 0.29 ENSMUST00000108437.8
serine (or cysteine) peptidase inhibitor, clade F, member 2
chr9_+_44013019 0.28 ENSMUST00000034654.9
ENSMUST00000206308.2
ENSMUST00000161381.8
membrane frizzled-related protein
chr19_+_24651362 0.28 ENSMUST00000057243.6
transmembrane protein 252
chr4_-_141351110 0.27 ENSMUST00000038661.8
solute carrier family 25, member 34
chr2_+_112097087 0.27 ENSMUST00000110987.9
ENSMUST00000028549.14
solute carrier family 12, member 6
chr6_+_15727798 0.27 ENSMUST00000128849.3
MyoD family inhibitor domain containing
chrX_+_101048650 0.26 ENSMUST00000144753.2
NHS-like 2
chr1_+_23801007 0.26 ENSMUST00000063663.6
beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)
chr2_-_32277773 0.26 ENSMUST00000050785.14
lipocalin 2
chr13_+_83652150 0.26 ENSMUST00000198199.5
myocyte enhancer factor 2C
chr2_-_142743354 0.26 ENSMUST00000211861.2
kinesin family member 16B
chr8_+_91555449 0.25 ENSMUST00000109614.9
chromodomain helicase DNA binding protein 9
chr6_-_102441628 0.24 ENSMUST00000032159.7
contactin 3
chr18_+_4994600 0.24 ENSMUST00000140448.8
supervillin
chr12_-_70394074 0.24 ENSMUST00000223160.2
ENSMUST00000222316.2
ENSMUST00000167755.3
ENSMUST00000110520.10
ENSMUST00000110522.10
ENSMUST00000221041.2
ENSMUST00000222603.3
tripartite motif-containing 9
chr9_+_21095399 0.24 ENSMUST00000115458.9
phosphodiesterase 4A, cAMP specific
chr6_+_83055581 0.24 ENSMUST00000177177.8
ENSMUST00000176089.2
polycomb group ring finger 1
chr2_-_165726610 0.24 ENSMUST00000177633.8
ENSMUST00000018050.14
ENSMUST00000088113.11
zinc finger, MYND-type containing 8
chr3_+_103740056 0.23 ENSMUST00000106822.2
BCLl2-like 15
chr2_+_51928017 0.23 ENSMUST00000065927.6
tumor necrosis factor alpha induced protein 6
chr19_-_34856853 0.23 ENSMUST00000036584.13
pantothenate kinase 1
chr2_+_118493713 0.23 ENSMUST00000099557.10
p21 (RAC1) activated kinase 6
chr6_+_126992549 0.23 ENSMUST00000000187.7
fibroblast growth factor 6
chr4_-_123466853 0.23 ENSMUST00000238555.2
microtubule-actin crosslinking factor 1
chr3_-_127202693 0.23 ENSMUST00000182078.9
ankyrin 2, brain
chr11_+_110914678 0.22 ENSMUST00000150902.8
ENSMUST00000178798.2
potassium inwardly-rectifying channel, subfamily J, member 16
chr8_+_111345209 0.22 ENSMUST00000034190.11
Vac14 homolog (S. cerevisiae)
chr2_-_22930188 0.22 ENSMUST00000114544.10
ENSMUST00000139038.8
ENSMUST00000126112.8
ENSMUST00000178908.2
ENSMUST00000078977.14
ENSMUST00000140164.8
ENSMUST00000149719.8
abl interactor 1
chr16_+_20513658 0.21 ENSMUST00000056518.13
family with sequence similarity 131, member A
chr6_+_125529911 0.20 ENSMUST00000112254.8
ENSMUST00000112253.6
Von Willebrand factor
chr15_-_64794139 0.20 ENSMUST00000023007.7
ENSMUST00000228014.2
adenylate cyclase 8
chr15_-_81581457 0.20 ENSMUST00000072910.6
chondroadherin-like
chr3_-_127202663 0.20 ENSMUST00000182008.8
ENSMUST00000182547.8
ankyrin 2, brain
chr9_+_121196034 0.19 ENSMUST00000210636.2
ENSMUST00000045903.8
trafficking protein, kinesin binding 1
chr17_+_35460722 0.18 ENSMUST00000068056.12
ENSMUST00000174757.8
ENSMUST00000173731.8
DEAD box helicase 39b
chr6_+_128376729 0.18 ENSMUST00000001561.12
nuclear receptor interacting protein 2
chr6_-_33037191 0.18 ENSMUST00000066379.11
coiled-coil-helix-coiled-coil-helix domain containing 3
chr6_+_68414401 0.17 ENSMUST00000103324.3
immunoglobulin kappa chain variable 15-103
chr13_+_83652280 0.17 ENSMUST00000199450.5
myocyte enhancer factor 2C
chr2_+_33106121 0.17 ENSMUST00000193373.3
angiopoietin-like 2
chrX_-_105647282 0.17 ENSMUST00000113480.2
cysteinyl leukotriene receptor 1
chr14_+_55728519 0.17 ENSMUST00000076236.7
capping protein regulator and myosin 1 linker 3
chr16_+_11223512 0.17 ENSMUST00000096273.9
sorting nexin 29
chr6_+_128376844 0.17 ENSMUST00000120405.4
nuclear receptor interacting protein 2
chr2_+_33106062 0.16 ENSMUST00000004208.7
angiopoietin-like 2
chr17_+_37836737 0.16 ENSMUST00000215424.2
olfactory receptor 111
chrX_+_100473161 0.15 ENSMUST00000033673.7
non-POU-domain-containing, octamer binding protein
chr11_+_87471867 0.14 ENSMUST00000018544.12
ENSMUST00000063156.11
ENSMUST00000107960.8
septin 4
chr6_+_72333209 0.14 ENSMUST00000206531.2
transmembrane protein 150A
chr13_+_42862957 0.14 ENSMUST00000066928.12
ENSMUST00000148891.8
phosphatase and actin regulator 1
chr9_-_106035332 0.14 ENSMUST00000112543.9
glycerate kinase
chr1_+_93271340 0.14 ENSMUST00000185498.7
protein phosphatase 1, regulatory subunit 7
chrX_-_58613428 0.14 ENSMUST00000119833.8
ENSMUST00000131319.8
fibroblast growth factor 13
chr15_+_10952418 0.13 ENSMUST00000022853.15
ENSMUST00000110523.2
C1q and tumor necrosis factor related protein 3
chr19_+_37674029 0.12 ENSMUST00000073391.5
cytochrome P450, family 26, subfamily c, polypeptide 1
chr1_-_134260666 0.12 ENSMUST00000168515.8
ENSMUST00000189361.2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
chr8_+_10056654 0.12 ENSMUST00000033892.9
tumor necrosis factor (ligand) superfamily, member 13b
chr7_+_18810097 0.12 ENSMUST00000032570.14
dystrophia myotonica-containing WD repeat motif
chr9_-_123546642 0.12 ENSMUST00000165754.8
ENSMUST00000026274.14
leucine zipper transcription factor-like 1
chr8_-_72019245 0.11 ENSMUST00000163659.3
ENSMUST00000048243.7
nucleoredoxin-like 1
chr7_+_18810167 0.11 ENSMUST00000108479.2
dystrophia myotonica-containing WD repeat motif
chr3_-_127202586 0.10 ENSMUST00000183095.3
ENSMUST00000182610.8
ankyrin 2, brain
chr6_-_24956296 0.10 ENSMUST00000127247.4
transmembrane protein 229A
chr8_-_68658694 0.10 ENSMUST00000212960.2
pleckstrin and Sec7 domain containing 3
chr17_-_15163362 0.10 ENSMUST00000238668.2
ENSMUST00000228330.2
WD repeat domain 27
chr4_+_114945905 0.10 ENSMUST00000171877.8
ENSMUST00000177647.8
ENSMUST00000106548.9
ENSMUST00000030488.3
PDZK1 interacting protein 1
chr11_+_49500090 0.09 ENSMUST00000020617.3
FMS-like tyrosine kinase 4
chr14_+_70694887 0.09 ENSMUST00000003561.10
phytanoyl-CoA hydroxylase interacting protein
chr9_+_32283779 0.09 ENSMUST00000047334.10
potassium inwardly-rectifying channel, subfamily J, member 1
chr12_-_81579614 0.08 ENSMUST00000169158.2
ENSMUST00000164431.2
ENSMUST00000163402.8
ENSMUST00000166664.2
ENSMUST00000164386.8
synaptojanin 2 binding protein
predicted gene 20498
chr6_-_119173699 0.08 ENSMUST00000239204.2
calcium channel, voltage-dependent, L type, alpha 1C subunit
chr1_+_90131702 0.08 ENSMUST00000065587.5
ENSMUST00000159654.2
atypical chemokine receptor 3
chr8_+_10056631 0.08 ENSMUST00000207792.3
tumor necrosis factor (ligand) superfamily, member 13b
chr11_+_115353290 0.07 ENSMUST00000106532.4
ENSMUST00000092445.12
ENSMUST00000153466.2
solute carrier family 16 (monocarboxylic acid transporters), member 5
chr12_-_76842263 0.07 ENSMUST00000082431.6
glutathione peroxidase 2
chr7_+_48993197 0.07 ENSMUST00000207743.2
neuron navigator 2
chr11_+_54205722 0.07 ENSMUST00000072178.11
ENSMUST00000101211.9
ENSMUST00000101213.9
ENSMUST00000064690.10
ENSMUST00000108899.8
acyl-CoA synthetase long-chain family member 6
chr2_-_86722536 0.07 ENSMUST00000111576.3
ENSMUST00000217403.2
olfactory receptor 1097
chr9_-_106343137 0.06 ENSMUST00000164834.3
G protein-coupled receptor 62
chr10_-_77587188 0.06 ENSMUST00000219969.2
predicted gene 9736
chr4_+_156214969 0.06 ENSMUST00000209248.2
ring finger 223
chr19_-_41732104 0.06 ENSMUST00000025993.10
slit guidance ligand 1
chr17_-_14279793 0.06 ENSMUST00000186636.3
predicted gene 7358
chr3_+_125197722 0.06 ENSMUST00000173932.8
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr3_+_123240562 0.06 ENSMUST00000029603.10
protease, serine 12 neurotrypsin (motopsin)
chr2_-_89893938 0.05 ENSMUST00000111506.3
ENSMUST00000216475.2
olfactory receptor 140
chr8_-_84903181 0.05 ENSMUST00000070102.6
ENSMUST00000210202.2
nanos C2HC-type zinc finger 3
chr9_+_40712562 0.05 ENSMUST00000117557.8
heat shock protein 8

Network of associatons between targets according to the STRING database.

First level regulatory network of Nfix

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.1 GO:0097167 circadian regulation of translation(GO:0097167)
0.5 3.0 GO:0071918 urea transmembrane transport(GO:0071918)
0.5 1.9 GO:0060434 bronchus morphogenesis(GO:0060434)
0.4 1.3 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.4 2.9 GO:0007527 adult somatic muscle development(GO:0007527)
0.4 1.6 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.4 1.5 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.4 3.4 GO:0071313 cellular response to caffeine(GO:0071313) positive regulation of the force of heart contraction(GO:0098735)
0.3 0.9 GO:0034758 antigen processing and presentation of exogenous peptide antigen via MHC class Ib(GO:0002477) antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent(GO:0002481) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440)
0.3 0.9 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.3 0.8 GO:0050973 detection of mechanical stimulus involved in equilibrioception(GO:0050973)
0.3 2.1 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.2 1.2 GO:0048690 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.2 2.1 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.2 1.2 GO:0071492 cellular response to UV-A(GO:0071492)
0.2 0.7 GO:0007208 phospholipase C-activating serotonin receptor signaling pathway(GO:0007208)
0.2 2.5 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.1 0.6 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 1.2 GO:0050957 equilibrioception(GO:0050957)
0.1 0.8 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1 2.3 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.1 0.8 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 1.3 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 0.4 GO:0050968 detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.1 0.7 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.1 0.8 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.1 0.9 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 0.5 GO:2000211 regulation of glutamate metabolic process(GO:2000211)
0.1 0.4 GO:0044330 canonical Wnt signaling pathway involved in positive regulation of wound healing(GO:0044330)
0.1 0.3 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.1 0.3 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 1.4 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.1 1.0 GO:0070995 NADPH oxidation(GO:0070995)
0.1 0.6 GO:0019372 lipoxygenase pathway(GO:0019372)
0.1 0.4 GO:0098907 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) regulation of SA node cell action potential(GO:0098907)
0.0 1.8 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.3 GO:0032346 positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349)
0.0 0.5 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.0 0.3 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
0.0 0.5 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.0 0.4 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.0 0.2 GO:0031296 B cell costimulation(GO:0031296)
0.0 0.2 GO:1903758 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.0 2.7 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.5 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.3 GO:0036506 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.0 0.2 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.0 0.3 GO:0003072 regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072)
0.0 0.1 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.0 0.5 GO:0042407 cristae formation(GO:0042407)
0.0 0.6 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.4 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.4 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.1 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.0 0.1 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 0.1 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.8 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:0009609 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
0.0 1.0 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 0.4 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.0 0.1 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.0 0.3 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.1 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.0 0.1 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
0.0 0.3 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.1 GO:1901979 renal sodium ion absorption(GO:0070294) regulation of inward rectifier potassium channel activity(GO:1901979)
0.0 0.2 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0070722 Tle3-Aes complex(GO:0070722)
0.3 1.2 GO:0072534 perineuronal net(GO:0072534)
0.2 1.9 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 0.4 GO:0043512 inhibin A complex(GO:0043512)
0.1 1.5 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 2.9 GO:0070938 contractile ring(GO:0070938)
0.1 0.6 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1 0.2 GO:0005687 U4 snRNP(GO:0005687)
0.1 1.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 1.2 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.1 1.8 GO:0000145 exocyst(GO:0000145)
0.1 0.5 GO:0061617 MICOS complex(GO:0061617)
0.1 0.9 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.5 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.1 1.6 GO:0031528 microvillus membrane(GO:0031528)
0.0 1.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 1.2 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 4.3 GO:0014704 intercalated disc(GO:0014704)
0.0 1.2 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.3 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.3 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.7 GO:0031143 pseudopodium(GO:0031143)
0.0 0.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.1 GO:0002095 caveolar macromolecular signaling complex(GO:0002095)
0.0 1.1 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.2 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.4 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 2.1 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0043202 lysosomal lumen(GO:0043202)
0.0 1.2 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.2 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 1.1 GO:0005811 lipid particle(GO:0005811)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.4 3.0 GO:0015265 urea channel activity(GO:0015265)
0.3 0.9 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.2 1.2 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.2 0.7 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.2 2.1 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.2 0.6 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.1 0.5 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 0.8 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.1 3.3 GO:0017166 vinculin binding(GO:0017166)
0.1 1.0 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.4 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1 1.8 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 1.2 GO:0046625 sphingolipid binding(GO:0046625)
0.1 0.3 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
0.1 0.8 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.4 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.9 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.7 GO:0051378 serotonin binding(GO:0051378)
0.0 3.6 GO:0070888 E-box binding(GO:0070888)
0.0 0.3 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.4 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 1.3 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.2 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 4.1 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.9 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.2 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.5 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.2 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 1.3 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.8 GO:0070412 R-SMAD binding(GO:0070412)
0.0 1.5 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 1.4 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.1 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.2 GO:0070700 BMP receptor binding(GO:0070700)
0.0 1.0 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.3 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.3 GO:0030957 Tat protein binding(GO:0030957)
0.0 1.9 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.1 GO:0031686 A1 adenosine receptor binding(GO:0031686)
0.0 0.1 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.0 0.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.2 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.3 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.3 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.0 2.1 GO:0008168 methyltransferase activity(GO:0008168)
0.0 0.7 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 2.1 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.8 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.8 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.8 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.7 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.9 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 1.0 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.9 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.5 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.3 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 3.4 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 1.9 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 3.0 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 3.7 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 0.7 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 0.9 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 1.6 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 2.1 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.4 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.5 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 1.8 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.6 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.7 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.6 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.5 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.2 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.2 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane