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avrg: GFI1 WT vs 36n/n vs KD

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Results for Nr1i2

Z-value: 3.15

Motif logo

Transcription factors associated with Nr1i2

Gene Symbol Gene ID Gene Info
ENSMUSG00000022809.5 nuclear receptor subfamily 1, group I, member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nr1i2mm39_v1_chr16_-_38115172_38115200-0.256.9e-01Click!

Activity profile of Nr1i2 motif

Sorted Z-values of Nr1i2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_96128196 3.44 ENSMUST00000090782.4
H2A clustered histone 20
chr2_+_129854256 2.83 ENSMUST00000110299.3
transglutaminase 3, E polypeptide
chr13_+_22220000 2.74 ENSMUST00000110455.4
H2B clustered histone 12
chr11_+_98851238 2.63 ENSMUST00000107473.3
retinoic acid receptor, alpha
chr9_-_39863342 2.29 ENSMUST00000216647.2
olfactory receptor 975
chrX_-_133062677 2.22 ENSMUST00000033611.5
X-linked Kx blood group related, X-linked
chr15_-_101268036 2.03 ENSMUST00000077196.6
keratin 80
chr12_-_99529767 2.03 ENSMUST00000176928.3
ENSMUST00000223484.2
forkhead box N3
chr7_+_5023552 1.98 ENSMUST00000208728.2
ENSMUST00000085427.6
coiled-coil domain containing 106
zinc finger protein 865
chr1_-_140111138 1.84 ENSMUST00000111976.9
ENSMUST00000066859.13
complement component factor h
chrX_-_20955370 1.77 ENSMUST00000040667.13
zinc finger protein 300
chr15_+_10224052 1.65 ENSMUST00000128450.8
ENSMUST00000148257.8
ENSMUST00000128921.8
prolactin receptor
chr3_-_107240989 1.61 ENSMUST00000061772.11
RNA binding motif protein 15
chr2_+_71811526 1.61 ENSMUST00000090826.12
ENSMUST00000102698.10
Rap guanine nucleotide exchange factor (GEF) 4
chr5_+_34527230 1.55 ENSMUST00000180376.8
family with sequence homology 193, member A
chr11_-_83483807 1.48 ENSMUST00000019071.4
chemokine (C-C motif) ligand 6
chr3_+_105778174 1.46 ENSMUST00000164730.2
ENSMUST00000010279.10
adenosine A3 receptor
transmembrane and immunoglobulin domain containing 3
chr3_-_129834788 1.46 ENSMUST00000168644.3
Sec24 related gene family, member B (S. cerevisiae)
chr1_-_140111018 1.45 ENSMUST00000192880.6
ENSMUST00000111977.8
complement component factor h
chr9_+_38491474 1.44 ENSMUST00000217160.3
olfactory receptor 912
chr19_+_11382092 1.43 ENSMUST00000153546.8
membrane-spanning 4-domains, subfamily A, member 4C
chr15_+_64689543 1.41 ENSMUST00000180105.2
predicted gene, 21798
chr14_+_58308004 1.40 ENSMUST00000165526.9
fibroblast growth factor 9
chr9_-_43027809 1.39 ENSMUST00000216126.2
ENSMUST00000213544.2
ENSMUST00000061833.6
TLC domain containing 5
chr4_-_119047167 1.36 ENSMUST00000030396.15
erythroblast membrane-associated protein
chr13_-_22219738 1.35 ENSMUST00000091742.6
H2A clustered histone 12
chr11_+_49434276 1.35 ENSMUST00000213256.2
olfactory receptor 1381
chr2_-_89951611 1.35 ENSMUST00000216493.2
ENSMUST00000214404.2
olfactory receptor 1269
chr6_-_42453259 1.34 ENSMUST00000204324.3
ENSMUST00000203396.3
olfactory receptor 457
chr4_-_119047202 1.34 ENSMUST00000239029.2
ENSMUST00000138395.9
ENSMUST00000156746.3
erythroblast membrane-associated protein
chr11_+_69011230 1.33 ENSMUST00000024543.3
hes family bHLH transcription factor 7
chr17_-_7652863 1.33 ENSMUST00000070059.5
unc-93 homolog A2
chr9_+_87026337 1.33 ENSMUST00000113149.8
ENSMUST00000049457.14
ENSMUST00000179313.3
melanocortin 2 receptor accessory protein 2
chr8_+_120163857 1.32 ENSMUST00000152420.8
ENSMUST00000212112.2
ENSMUST00000098365.4
oxidative stress induced growth inhibitor 1
chr18_-_78166595 1.30 ENSMUST00000091813.12
solute carrier family 14 (urea transporter), member 1
chr7_-_28297565 1.26 ENSMUST00000040531.9
ENSMUST00000108283.8
sterile alpha motif domain containing 4B
p21 (RAC1) activated kinase 4
chr14_+_20732804 1.26 ENSMUST00000228545.2
Sec24 related gene family, member C (S. cerevisiae)
chr9_+_53448322 1.24 ENSMUST00000035850.8
nuclear protein in the AT region
chr10_-_81436671 1.22 ENSMUST00000151858.8
ENSMUST00000142948.8
ENSMUST00000072020.9
transducin-like enhancer of split 6
chr2_-_92290054 1.21 ENSMUST00000136718.2
solute carrier family 35, member C1
chr13_-_93328619 1.20 ENSMUST00000224464.2
terminal nucleotidyltransferase 2
chr2_+_172864153 1.20 ENSMUST00000173997.2
RNA binding motif protein 38
chr13_-_98951890 1.20 ENSMUST00000040340.16
ENSMUST00000179563.8
ENSMUST00000109403.2
FCH domain only 2
chrX_+_10351360 1.17 ENSMUST00000076354.13
ENSMUST00000115526.2
tetraspanin 7
chr2_+_117942357 1.17 ENSMUST00000039559.9
thrombospondin 1
chr5_-_125119855 1.15 ENSMUST00000125053.8
nuclear receptor co-repressor 2
chr17_-_45125468 1.15 ENSMUST00000159943.8
ENSMUST00000160673.8
runt related transcription factor 2
chr12_+_102249375 1.14 ENSMUST00000101114.11
ENSMUST00000150795.8
Ras and Rab interactor 3
chr11_+_116324913 1.14 ENSMUST00000057676.7
UBA-like domain containing 2
chr14_+_25459690 1.12 ENSMUST00000007961.15
zinc finger, MIZ-type containing 1
chr8_+_85807369 1.11 ENSMUST00000079764.14
WD repeat domain 83 opposite strand
chr15_-_5273659 1.07 ENSMUST00000047379.15
prostaglandin E receptor 4 (subtype EP4)
chr3_+_97920819 1.06 ENSMUST00000079812.8
notch 2
chr15_-_5273645 1.06 ENSMUST00000120563.2
prostaglandin E receptor 4 (subtype EP4)
chr7_-_43155351 1.05 ENSMUST00000191516.7
ENSMUST00000013497.8
ENSMUST00000163619.8
RIKEN cDNA 4931406B18 gene
chr5_+_52521133 1.04 ENSMUST00000101208.6
superoxide dismutase 3, extracellular
chr2_+_89865681 1.03 ENSMUST00000214855.2
olfactory receptor 1265
chr8_-_70975734 1.03 ENSMUST00000137610.3
KxDL motif containing 1
chr13_+_109397184 1.03 ENSMUST00000153234.8
phosphodiesterase 4D, cAMP specific
chr7_-_19621833 1.03 ENSMUST00000052605.8
carcinoembryonic antigen-related cell adhesion molecule 19
chr4_-_141265745 1.01 ENSMUST00000078886.10
spen family transcription repressor
chr1_+_59296065 1.01 ENSMUST00000160662.8
ENSMUST00000114248.3
cyclin-dependent kinase 15
chr8_-_106198112 1.00 ENSMUST00000014990.13
tubulin polymerization-promoting protein family member 3
chr3_-_95902949 0.99 ENSMUST00000123006.8
ENSMUST00000130043.8
pleckstrin homology domain containing, family O member 1
chr7_+_3352019 0.99 ENSMUST00000100301.11
protein kinase C, gamma
chr1_-_74544946 0.97 ENSMUST00000044260.11
ENSMUST00000186282.7
ubiquitin specific peptidase 37
chr9_+_106247943 0.96 ENSMUST00000173748.2
dual specificity phosphatase 7
chr5_+_109567554 0.96 ENSMUST00000232833.2
ENSMUST00000232722.2
ENSMUST00000233536.2
ENSMUST00000171841.3
ENSMUST00000233038.2
ENSMUST00000233724.2
vomeronasal 2, receptor 17
chr2_-_90410922 0.95 ENSMUST00000168621.3
protein tyrosine phosphatase, receptor type, J
chr7_+_28869770 0.95 ENSMUST00000033886.8
ENSMUST00000209019.2
ENSMUST00000208330.2
gametogenetin
chr6_-_5496261 0.94 ENSMUST00000203347.3
ENSMUST00000019721.7
pyruvate dehydrogenase kinase, isoenzyme 4
chr17_-_36220924 0.94 ENSMUST00000141662.8
ENSMUST00000056034.13
ENSMUST00000077494.13
ENSMUST00000149277.8
ENSMUST00000061052.12
alpha tubulin acetyltransferase 1
chr6_+_11907808 0.93 ENSMUST00000155037.4
PHD finger protein 14
chr4_-_41275091 0.93 ENSMUST00000030143.13
ENSMUST00000108068.8
ubiquitin-associated protein 2
chr13_+_44883270 0.93 ENSMUST00000172830.8
jumonji, AT rich interactive domain 2
chr5_+_31107390 0.93 ENSMUST00000006814.9
abhydrolase domain containing 1
chr19_-_12302465 0.92 ENSMUST00000207241.3
olfactory receptor 1437
chr12_+_37292029 0.91 ENSMUST00000160390.2
alkylglycerol monooxygenase
chr5_+_16758538 0.90 ENSMUST00000199581.5
hepatocyte growth factor
chr5_-_110596387 0.90 ENSMUST00000198768.3
fibrosin-like 1
chr2_-_168072295 0.89 ENSMUST00000154111.8
dolichol-phosphate (beta-D) mannosyltransferase 1
chr9_+_107457316 0.89 ENSMUST00000093785.6
N(alpha)-acetyltransferase 80, NatH catalytic subunit
chr2_+_83554770 0.89 ENSMUST00000141725.3
integrin alpha V
chr13_+_22656093 0.89 ENSMUST00000226330.2
ENSMUST00000226965.2
vomeronasal 1 receptor 201
chr8_-_85500998 0.89 ENSMUST00000109762.8
nuclear factor I/X
chr2_+_156154219 0.88 ENSMUST00000037096.9
cyclic nucleotide binding domain containing 2
chr15_-_77653979 0.87 ENSMUST00000229259.2
myosin, heavy polypeptide 9, non-muscle
chr19_+_13594739 0.87 ENSMUST00000217061.3
ENSMUST00000209005.4
ENSMUST00000208347.3
olfactory receptor 1487
chr1_-_64995982 0.87 ENSMUST00000097713.2
pleckstrin homology domain containing, family M, member 3
chr3_-_52012462 0.86 ENSMUST00000121440.4
mastermind like transcriptional coactivator 3
chr7_+_24048613 0.86 ENSMUST00000032683.6
Ly6/Plaur domain containing 5
chr10_-_12745109 0.85 ENSMUST00000218635.2
utrophin
chr15_+_7159038 0.83 ENSMUST00000067190.12
ENSMUST00000164529.9
LIF receptor alpha
chr4_-_139695337 0.82 ENSMUST00000105031.4
kelch domain containing 7A
chr16_+_75389732 0.82 ENSMUST00000046378.14
ENSMUST00000114249.8
ENSMUST00000114253.2
RNA binding motif protein 11
chrX_+_95139639 0.82 ENSMUST00000117399.2
moesin
chr14_+_25459630 0.81 ENSMUST00000162645.8
zinc finger, MIZ-type containing 1
chrX_-_165368675 0.80 ENSMUST00000000412.3
EGF-like-domain, multiple 6
chr2_+_71042172 0.79 ENSMUST00000081710.12
dynein cytoplasmic 1 intermediate chain 2
chr15_-_35938328 0.79 ENSMUST00000014457.15
cytochrome c oxidase subunit 6C
chrX_-_48823936 0.78 ENSMUST00000215373.3
olfactory receptor 1321
chr13_+_23758555 0.78 ENSMUST00000090776.7
H2A clustered histone 7
chr1_+_36730530 0.78 ENSMUST00000081180.7
ENSMUST00000193210.6
ENSMUST00000195151.6
cytochrome c oxidase subunit 5B
chr9_+_77959206 0.78 ENSMUST00000024104.9
glial cells missing homolog 1
chr17_-_37523969 0.76 ENSMUST00000060728.7
ENSMUST00000216318.2
olfactory receptor 95
chr10_-_93425553 0.76 ENSMUST00000020203.7
small nuclear ribonucleoprotein polypeptide F
chr14_-_51134930 0.75 ENSMUST00000227271.2
kelch-like 33
chrX_+_99537897 0.75 ENSMUST00000033570.6
immunoglobulin (CD79A) binding protein 1
chr5_+_121358254 0.75 ENSMUST00000042614.13
HECT domain E3 ubiquitin protein ligase 4
chr16_-_89940652 0.75 ENSMUST00000114124.9
T cell lymphoma invasion and metastasis 1
chr7_+_27879650 0.74 ENSMUST00000172467.8
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr19_+_53131187 0.73 ENSMUST00000050096.15
ENSMUST00000237832.2
adducin 3 (gamma)
chr17_+_47747657 0.72 ENSMUST00000150819.3
expressed sequence AI661453
chr16_+_10363222 0.72 ENSMUST00000155633.8
ENSMUST00000066345.15
C-type lectin domain family 16, member A
chr7_+_107649900 0.71 ENSMUST00000214599.2
ENSMUST00000209805.3
olfactory receptor 479
chr11_-_62622691 0.71 ENSMUST00000150336.8
zinc finger protein 287
chr14_+_66378382 0.69 ENSMUST00000022620.11
cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal)
chr13_-_17979675 0.69 ENSMUST00000223490.2
cyclin-dependent kinase 13
chr5_+_16758777 0.69 ENSMUST00000030683.8
hepatocyte growth factor
chr1_+_92545510 0.69 ENSMUST00000213247.2
olfactory receptor 12
chr10_-_78688000 0.69 ENSMUST00000205100.3
olfactory receptor 1356
chr1_-_183126875 0.69 ENSMUST00000195233.3
melanoma inhibitory activity 3
chr6_-_142910094 0.67 ENSMUST00000032421.4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr11_-_69088635 0.66 ENSMUST00000094078.4
ENSMUST00000021262.10
arachidonate 8-lipoxygenase
chr14_+_50741057 0.66 ENSMUST00000217437.2
ENSMUST00000213935.2
olfactory receptor 742
chr2_-_153079828 0.65 ENSMUST00000109795.2
pleiomorphic adenoma gene-like 2
chrX_+_72760183 0.65 ENSMUST00000002084.14
ATP-binding cassette, sub-family D (ALD), member 1
chr11_-_78950698 0.65 ENSMUST00000141409.8
kinase suppressor of ras 1
chr15_+_99291491 0.65 ENSMUST00000159531.3
transmembrane BAX inhibitor motif containing 6
chr15_-_74624811 0.65 ENSMUST00000189128.2
ENSMUST00000023259.15
Ly6/neurotoxin 1
chr15_+_84565174 0.65 ENSMUST00000065499.5
proline rich 5 (renal)
chr8_-_70975813 0.64 ENSMUST00000121623.8
ENSMUST00000093456.12
ENSMUST00000118850.8
KxDL motif containing 1
chr4_-_123507494 0.64 ENSMUST00000238866.2
microtubule-actin crosslinking factor 1
chr2_+_164802766 0.64 ENSMUST00000202223.4
solute carrier family 12, member 5
chr8_-_70448872 0.63 ENSMUST00000177851.9
GATA zinc finger domain containing 2A
chr14_+_62793175 0.63 ENSMUST00000039064.8
family with sequence similarity 124, member A
chr15_-_66432938 0.63 ENSMUST00000048372.7
transmembrane protein 71
chr2_-_92290128 0.63 ENSMUST00000067631.7
solute carrier family 35, member C1
chr13_-_93328719 0.62 ENSMUST00000048702.7
terminal nucleotidyltransferase 2
chr19_+_8568618 0.62 ENSMUST00000170817.2
ENSMUST00000010251.11
solute carrier family 22 (organic anion transporter), member 8
chr7_-_30262659 0.62 ENSMUST00000043898.8
presenilin enhancer gamma secretase subunit
chr17_-_36220518 0.62 ENSMUST00000141132.2
alpha tubulin acetyltransferase 1
chr4_+_44756608 0.61 ENSMUST00000143385.2
zinc finger, CCHC domain containing 7
chr17_+_31120785 0.61 ENSMUST00000114574.3
glucagon-like peptide 1 receptor
chr7_-_57036920 0.61 ENSMUST00000068911.13
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3
chr9_+_119978773 0.61 ENSMUST00000068698.15
ENSMUST00000215512.2
ENSMUST00000111627.3
ENSMUST00000093773.8
myelin-associated oligodendrocytic basic protein
chr16_+_3648742 0.61 ENSMUST00000214238.2
ENSMUST00000214590.2
olfactory receptor 15
chr11_-_63970270 0.60 ENSMUST00000049091.9
heme A:farnesyltransferase cytochrome c oxidase assembly factor 10
chr10_+_59057767 0.60 ENSMUST00000182161.2
sosondowah ankyrin repeat domain family member C
chr3_-_142101339 0.60 ENSMUST00000198381.5
ENSMUST00000090134.12
ENSMUST00000196908.5
PDZ and LIM domain 5
chr13_-_93328883 0.60 ENSMUST00000225868.2
terminal nucleotidyltransferase 2
chr2_+_71042050 0.59 ENSMUST00000112142.8
ENSMUST00000112139.8
ENSMUST00000112140.8
ENSMUST00000112138.8
dynein cytoplasmic 1 intermediate chain 2
chr11_-_54751738 0.59 ENSMUST00000144164.9
LYR motif containing 7
chr17_+_15163466 0.59 ENSMUST00000164837.3
ENSMUST00000174004.2
RIKEN cDNA 1600012H06 gene
chr17_-_79292856 0.59 ENSMUST00000118991.2
protein kinase D3
chr5_+_16758897 0.58 ENSMUST00000196645.2
hepatocyte growth factor
chr8_+_84852609 0.58 ENSMUST00000093380.5
podocan-like 1
chr1_+_6284823 0.58 ENSMUST00000027040.13
RB1-inducible coiled-coil 1
chr11_-_69556888 0.58 ENSMUST00000108654.3
CD68 antigen
chr16_+_84631789 0.58 ENSMUST00000114184.8
GA repeat binding protein, alpha
chr9_-_32255604 0.57 ENSMUST00000034533.7
potassium inwardly-rectifying channel, subfamily J, member 5
chr15_-_98118858 0.56 ENSMUST00000142443.8
ENSMUST00000170618.8
predicted gene 44579
olfactory receptor 287
chr5_-_114911509 0.56 ENSMUST00000086564.11
GIT ArfGAP 2
chr11_-_33463627 0.55 ENSMUST00000037522.14
RAN binding protein 17
chr16_+_14523696 0.55 ENSMUST00000023356.8
snail family zinc finger 2
chr1_-_155848917 0.53 ENSMUST00000138762.8
centrosomal protein 350
chr4_+_43669266 0.53 ENSMUST00000107864.8
transmembrane protein 8B
chr4_+_124774692 0.53 ENSMUST00000059343.7
Eph receptor A10
chr5_-_136594286 0.52 ENSMUST00000176172.8
cut-like homeobox 1
chr19_-_4527475 0.52 ENSMUST00000059295.10
synaptotagmin XII
chr3_+_79791798 0.52 ENSMUST00000118853.8
ENSMUST00000145992.2
golgi associated kinase 1B
chr7_+_28869629 0.51 ENSMUST00000098609.4
gametogenetin
chr5_-_136596299 0.51 ENSMUST00000004097.16
cut-like homeobox 1
chr17_-_56891576 0.51 ENSMUST00000075510.12
scaffold attachment factor B2
chr16_+_15705141 0.50 ENSMUST00000096232.6
CCAAT/enhancer binding protein (C/EBP), delta
chr1_-_170133901 0.50 ENSMUST00000179801.3
predicted gene 7694
chr7_-_6511472 0.50 ENSMUST00000207055.3
ENSMUST00000209097.2
ENSMUST00000208623.3
ENSMUST00000208207.2
ENSMUST00000209029.4
ENSMUST00000214383.2
ENSMUST00000207624.2
ENSMUST00000213549.2
olfactory receptor 1348
chr14_-_72946972 0.50 ENSMUST00000162478.8
fibronectin type III domain containing 3A
chr9_-_107474221 0.50 ENSMUST00000238519.2
leucine-rich single-pass membrane protein 2
chr6_+_71520855 0.49 ENSMUST00000204535.2
ENSMUST00000065364.5
ENSMUST00000204199.2
charged multivesicular body protein 3
chr11_+_29324348 0.49 ENSMUST00000239407.2
coiled coil domain containing 88A
chr11_+_67477347 0.49 ENSMUST00000108682.9
growth arrest specific 7
chr10_-_81102740 0.49 ENSMUST00000046114.5
mitochondrial ribosomal protein L54
chr8_-_70573465 0.47 ENSMUST00000002412.9
neurocan
chr9_-_62888156 0.47 ENSMUST00000098651.6
ENSMUST00000214830.2
protein inhibitor of activated STAT 1
chr6_+_90596123 0.47 ENSMUST00000032177.10
solute carrier family 41, member 3
chr19_-_7083094 0.47 ENSMUST00000113383.4
fibronectin leucine rich transmembrane protein 1
chr1_-_170886924 0.47 ENSMUST00000164044.8
ENSMUST00000169017.8
Fc receptor, IgG, low affinity III
chr4_+_109264284 0.46 ENSMUST00000064129.14
ENSMUST00000106619.8
tetratricopeptide repeat domain 39A
chr6_+_22288220 0.46 ENSMUST00000128245.8
ENSMUST00000031681.10
ENSMUST00000148639.2
wingless-type MMTV integration site family, member 16
chr6_+_129489501 0.46 ENSMUST00000032263.7
transmembrane protein 52B
chr10_-_5500636 0.46 ENSMUST00000215295.2
ENSMUST00000041639.7
spectrin repeat containing, nuclear envelope 1
chrX_+_101048650 0.46 ENSMUST00000144753.2
NHS-like 2
chr6_-_120341304 0.45 ENSMUST00000146667.2
coiled-coil domain containing 77
chr1_-_179345556 0.44 ENSMUST00000194237.2
ENSMUST00000128302.8
ENSMUST00000111134.2
SET and MYND domain containing 3
chr8_+_66838927 0.44 ENSMUST00000039540.12
ENSMUST00000110253.3
membrane associated ring-CH-type finger 1
chr5_-_143513732 0.44 ENSMUST00000100489.4
ENSMUST00000080537.14
Rac family small GTPase 1
chr19_-_47079052 0.44 ENSMUST00000235771.2
ENSMUST00000096014.5
ENSMUST00000236170.2
ATP synthase membrane subunit DAPIT
chr11_-_114892706 0.44 ENSMUST00000092464.10
CD300C molecule 2
chr10_-_78453908 0.43 ENSMUST00000095473.6
ENSMUST00000213877.2
ENSMUST00000203305.3
olfactory receptor 1357

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr1i2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.7 2.1 GO:2000388 negative regulation of integrin activation(GO:0033624) regulation of matrix metallopeptidase secretion(GO:1904464) matrix metallopeptidase secretion(GO:1990773) positive regulation of ovarian follicle development(GO:2000386) regulation of antral ovarian follicle growth(GO:2000387) positive regulation of antral ovarian follicle growth(GO:2000388) negative regulation of eosinophil migration(GO:2000417)
0.6 1.7 GO:0038161 prolactin signaling pathway(GO:0038161)
0.5 1.6 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.4 1.3 GO:0098749 cerebellar neuron development(GO:0098749)
0.4 3.7 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.4 1.2 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) negative regulation of nitric oxide mediated signal transduction(GO:0010751) regulation of cGMP-mediated signaling(GO:0010752) negative regulation of endothelial cell chemotaxis(GO:2001027)
0.4 1.5 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.4 1.1 GO:1990705 intrahepatic bile duct development(GO:0035622) cholangiocyte proliferation(GO:1990705)
0.3 1.6 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
0.3 1.9 GO:0007296 vitellogenesis(GO:0007296)
0.3 0.9 GO:2000536 negative regulation of entry of bacterium into host cell(GO:2000536)
0.3 1.2 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.2 0.7 GO:1904266 regulation of Schwann cell chemotaxis(GO:1904266) positive regulation of Schwann cell chemotaxis(GO:1904268) Schwann cell chemotaxis(GO:1990751)
0.2 2.7 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.2 1.4 GO:0071918 urea transmembrane transport(GO:0071918)
0.2 0.7 GO:1904766 negative regulation of macroautophagy by TORC1 signaling(GO:1904766)
0.2 0.9 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.2 0.7 GO:0040040 thermosensory behavior(GO:0040040)
0.2 0.7 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.2 0.7 GO:0034378 chylomicron assembly(GO:0034378)
0.2 0.9 GO:1903923 protein processing in phagocytic vesicle(GO:1900756) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923)
0.2 0.6 GO:0061723 glycophagy(GO:0061723)
0.2 0.8 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.2 1.2 GO:0032423 regulation of mismatch repair(GO:0032423)
0.2 0.9 GO:2000583 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.2 0.6 GO:0003273 cell migration involved in endocardial cushion formation(GO:0003273) negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.2 2.4 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.2 2.2 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.2 0.5 GO:0001788 antibody-dependent cellular cytotoxicity(GO:0001788)
0.2 0.6 GO:0034635 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.2 0.6 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 1.5 GO:0002553 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.1 0.4 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.1 0.4 GO:0098583 mastication(GO:0071626) learned vocalization behavior(GO:0098583)
0.1 0.7 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 0.8 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 1.3 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 0.9 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 1.4 GO:2000582 regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 0.9 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.1 0.9 GO:0007527 adult somatic muscle development(GO:0007527)
0.1 0.6 GO:0018343 protein farnesylation(GO:0018343)
0.1 1.0 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.1 1.8 GO:0030259 lipid glycosylation(GO:0030259)
0.1 0.2 GO:0002344 peripheral B cell selection(GO:0002343) B cell affinity maturation(GO:0002344)
0.1 1.2 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 0.3 GO:0071799 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.1 0.2 GO:1990051 activation of protein kinase C activity(GO:1990051)
0.1 1.2 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.1 0.5 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.1 0.3 GO:0071846 actin filament debranching(GO:0071846)
0.1 0.3 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.1 2.0 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.1 0.6 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 1.4 GO:0060484 positive regulation of activin receptor signaling pathway(GO:0032927) lung-associated mesenchyme development(GO:0060484)
0.1 0.3 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.1 0.4 GO:0090210 regulation of establishment of blood-brain barrier(GO:0090210)
0.1 2.8 GO:0031424 keratinization(GO:0031424)
0.1 0.6 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 0.5 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.1 0.3 GO:0061402 glycerol biosynthetic process(GO:0006114) positive regulation of transcription from RNA polymerase II promoter in response to acidic pH(GO:0061402)
0.1 1.0 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 1.2 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.1 1.0 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 1.2 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.1 0.3 GO:0071677 positive regulation of mononuclear cell migration(GO:0071677)
0.1 0.6 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.3 GO:2000983 regulation of ATP citrate synthase activity(GO:2000983) negative regulation of ATP citrate synthase activity(GO:2000984)
0.1 1.2 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 0.3 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.1 0.6 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.1 0.6 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.1 0.4 GO:0032627 interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667)
0.1 0.6 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.1 0.9 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 0.4 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.1 0.2 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.1 0.3 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1 0.3 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
0.1 0.4 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.1 GO:0021623 oculomotor nerve morphogenesis(GO:0021622) oculomotor nerve formation(GO:0021623)
0.1 0.3 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.6 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.0 0.1 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.2 GO:0030167 proteoglycan catabolic process(GO:0030167) regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0 0.3 GO:0051775 response to redox state(GO:0051775)
0.0 0.1 GO:0031446 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.0 0.9 GO:0051451 myoblast migration(GO:0051451)
0.0 0.2 GO:0061056 sclerotome development(GO:0061056)
0.0 1.3 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.2 GO:0042494 detection of bacterial lipoprotein(GO:0042494)
0.0 0.3 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.0 0.1 GO:0060466 activation of meiosis involved in egg activation(GO:0060466)
0.0 0.8 GO:0021707 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 1.6 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 1.9 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.2 GO:0015889 cobalamin transport(GO:0015889)
0.0 1.6 GO:0060008 Sertoli cell differentiation(GO:0060008)
0.0 0.1 GO:0061550 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) substrate-dependent cerebral cortex tangential migration(GO:0021825) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) cranial ganglion development(GO:0061550) trigeminal ganglion development(GO:0061551) facioacoustic ganglion development(GO:1903375)
0.0 0.5 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.3 GO:0046544 development of secondary male sexual characteristics(GO:0046544)
0.0 0.8 GO:0060632 regulation of microtubule-based movement(GO:0060632)
0.0 0.1 GO:1900157 regulation of bone mineralization involved in bone maturation(GO:1900157)
0.0 0.1 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.0 0.1 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.0 0.7 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.0 GO:0042335 cuticle development(GO:0042335)
0.0 0.5 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.4 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.1 GO:2000354 regulation of ovarian follicle development(GO:2000354)
0.0 0.3 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 1.1 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.6 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.1 GO:0046959 habituation(GO:0046959)
0.0 0.6 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.2 GO:0042256 mature ribosome assembly(GO:0042256)
0.0 0.2 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.0 0.2 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.0 0.4 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.0 0.2 GO:0036309 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) regulation of SA node cell action potential(GO:0098907)
0.0 0.1 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.0 0.1 GO:0050812 regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 1.6 GO:0042491 auditory receptor cell differentiation(GO:0042491)
0.0 1.0 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.3 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.7 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.0 0.2 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.4 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.5 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.0 0.2 GO:0051683 establishment of Golgi localization(GO:0051683)
0.0 0.3 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.2 GO:0075044 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.0 1.3 GO:0097009 energy homeostasis(GO:0097009)
0.0 0.1 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.4 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.0 0.1 GO:1903542 negative regulation of exosomal secretion(GO:1903542)
0.0 1.3 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.5 GO:0035376 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.0 0.2 GO:0002175 protein localization to paranode region of axon(GO:0002175) paranodal junction assembly(GO:0030913)
0.0 1.7 GO:0032418 lysosome localization(GO:0032418)
0.0 0.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.3 GO:1904667 negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.0 0.3 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.0 0.2 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.2 GO:0002176 male germ cell proliferation(GO:0002176)
0.0 0.0 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.0 0.2 GO:0034770 negative regulation of transcription from RNA polymerase I promoter(GO:0016479) histone H4-K20 methylation(GO:0034770)
0.0 0.7 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.0 GO:1903116 positive regulation of actin filament-based movement(GO:1903116)
0.0 0.9 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.7 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.2 GO:0061436 establishment of skin barrier(GO:0061436)
0.0 1.4 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.4 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.2 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.1 GO:0010764 negative regulation of fibroblast migration(GO:0010764)
0.0 0.1 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.3 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.0 GO:0010269 response to selenium ion(GO:0010269)
0.0 0.0 GO:0090420 naphthalene metabolic process(GO:0018931) naphthalene-containing compound metabolic process(GO:0090420)
0.0 0.0 GO:0015680 intracellular copper ion transport(GO:0015680)
0.0 0.2 GO:0021542 dentate gyrus development(GO:0021542)
0.0 0.3 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.1 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.0 0.7 GO:0060612 adipose tissue development(GO:0060612)
0.0 1.1 GO:0007566 embryo implantation(GO:0007566)
0.0 0.0 GO:0006500 N-terminal protein palmitoylation(GO:0006500)
0.0 0.6 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.0 GO:0072076 nephrogenic mesenchyme development(GO:0072076)
0.0 0.3 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.4 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.2 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.3 GO:0071384 cellular response to corticosteroid stimulus(GO:0071384) cellular response to glucocorticoid stimulus(GO:0071385)
0.0 0.3 GO:0046688 response to copper ion(GO:0046688)
0.0 0.0 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.0 0.0 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.2 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.1 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.0 0.3 GO:1903817 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 0.2 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.0 0.1 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 17.0 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.7 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.2 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.1 GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002924)
0.0 0.1 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.0 0.8 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.5 GO:0032728 positive regulation of interferon-beta production(GO:0032728)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0098835 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835)
0.3 1.6 GO:0044316 cone cell pedicle(GO:0044316)
0.2 0.7 GO:0036020 endolysosome membrane(GO:0036020)
0.2 0.7 GO:0002945 cyclin K-CDK13 complex(GO:0002945)
0.2 0.9 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.2 0.9 GO:0034686 integrin alphav-beta3 complex(GO:0034683) integrin alphav-beta8 complex(GO:0034686)
0.2 2.6 GO:0097427 microtubule bundle(GO:0097427)
0.2 3.1 GO:0030127 COPII vesicle coat(GO:0030127)
0.2 1.2 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.1 1.2 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.8 GO:0005683 U7 snRNP(GO:0005683)
0.1 0.9 GO:0097513 myosin II filament(GO:0097513)
0.1 0.9 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 0.3 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.1 1.2 GO:0060091 kinocilium(GO:0060091)
0.1 2.8 GO:0001533 cornified envelope(GO:0001533)
0.1 0.3 GO:0005757 mitochondrial permeability transition pore complex(GO:0005757)
0.1 0.4 GO:0044307 dendritic branch(GO:0044307)
0.1 1.7 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 0.6 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.5 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 2.0 GO:0031527 filopodium membrane(GO:0031527)
0.1 0.6 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 2.3 GO:0045095 keratin filament(GO:0045095)
0.0 1.0 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.3 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.6 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.2 GO:0005914 spot adherens junction(GO:0005914)
0.0 0.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.4 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.1 GO:1990879 CST complex(GO:1990879)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.4 GO:0097451 glial limiting end-foot(GO:0097451)
0.0 0.9 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.3 GO:0070552 BRISC complex(GO:0070552)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.4 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.9 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.6 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.3 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.3 GO:0034464 BBSome(GO:0034464)
0.0 0.1 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.2 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.3 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.1 GO:1990696 USH2 complex(GO:1990696)
0.0 0.1 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.0 0.2 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.5 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 1.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.9 GO:0001772 immunological synapse(GO:0001772)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 1.5 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.2 GO:0032982 myosin filament(GO:0032982)
0.0 0.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.8 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 1.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.3 GO:0001851 complement component C3b binding(GO:0001851)
0.4 1.3 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.4 1.2 GO:0070052 collagen V binding(GO:0070052)
0.4 1.2 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.3 1.0 GO:0050479 glyceryl-ether monooxygenase activity(GO:0050479)
0.3 2.8 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.3 1.8 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.2 0.9 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.2 0.7 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.2 0.9 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.2 1.4 GO:0015265 urea channel activity(GO:0015265)
0.2 0.6 GO:0004967 glucagon receptor activity(GO:0004967)
0.2 1.0 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.2 0.8 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.2 0.7 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.2 2.6 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.2 1.6 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 0.9 GO:0050051 leukotriene-B4 20-monooxygenase activity(GO:0050051)
0.1 1.5 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 0.7 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.3 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.1 0.6 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.1 0.3 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.1 0.9 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.1 0.7 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 0.7 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.4 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 0.3 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
0.1 1.1 GO:0070097 delta-catenin binding(GO:0070097)
0.1 1.0 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.3 GO:0031370 eukaryotic initiation factor 4G binding(GO:0031370)
0.1 0.6 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 0.9 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 0.5 GO:0019770 IgG receptor activity(GO:0019770)
0.1 0.2 GO:0005110 frizzled-2 binding(GO:0005110)
0.1 0.5 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.6 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.1 0.5 GO:0030172 troponin C binding(GO:0030172)
0.1 1.0 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 2.2 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.3 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 0.6 GO:0015651 quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.1 1.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.5 GO:0032052 bile acid binding(GO:0032052)
0.1 1.7 GO:0042056 chemoattractant activity(GO:0042056)
0.1 1.0 GO:0042166 acetylcholine binding(GO:0042166)
0.1 2.5 GO:0030552 cAMP binding(GO:0030552)
0.1 0.9 GO:0043495 protein anchor(GO:0043495)
0.0 0.4 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.2 GO:0051435 BH4 domain binding(GO:0051435)
0.0 1.6 GO:0008009 chemokine activity(GO:0008009)
0.0 1.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.6 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 1.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.7 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.6 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.8 GO:0030551 cyclic nucleotide binding(GO:0030551)
0.0 0.4 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.3 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.2 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.0 1.2 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.2 GO:0008607 cAMP-dependent protein kinase regulator activity(GO:0008603) phosphorylase kinase regulator activity(GO:0008607)
0.0 0.0 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.3 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.3 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.1 GO:0051538 succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.0 0.2 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.2 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0 1.6 GO:0030332 cyclin binding(GO:0030332)
0.0 0.3 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.2 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 1.0 GO:0043236 laminin binding(GO:0043236)
0.0 0.4 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0 0.2 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.6 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.2 GO:0015277 AMPA glutamate receptor activity(GO:0004971) kainate selective glutamate receptor activity(GO:0015277)
0.0 0.1 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0 0.7 GO:0017166 vinculin binding(GO:0017166)
0.0 0.6 GO:0005521 lamin binding(GO:0005521)
0.0 0.2 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.1 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.2 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.3 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.5 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.7 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.3 GO:0005243 gap junction channel activity(GO:0005243)
0.0 1.2 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.7 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 1.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.9 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.7 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.1 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.6 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 1.6 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.5 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.4 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.3 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.2 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.0 GO:0004802 transketolase activity(GO:0004802)
0.0 1.6 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.6 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.2 GO:0008301 DNA binding, bending(GO:0008301)
0.0 2.2 GO:0000149 SNARE binding(GO:0000149)
0.0 1.3 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.1 GO:1903136 cuprous ion binding(GO:1903136)
0.0 0.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.1 GO:0002046 opsin binding(GO:0002046)
0.0 0.1 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0001163 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 16.8 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.0 GO:0004008 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.0 0.2 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.9 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 3.6 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.7 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 3.9 PID FGF PATHWAY FGF signaling pathway
0.0 1.4 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.9 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.4 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 1.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.3 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 2.1 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.1 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.6 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.8 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.3 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.5 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.1 PID ALK2 PATHWAY ALK2 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.2 2.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.2 3.1 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 2.0 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 1.7 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 1.7 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.1 2.0 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 0.9 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 1.0 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 1.0 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 0.8 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 1.1 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 1.3 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 1.0 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 1.9 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 1.2 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.6 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 1.5 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.9 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.5 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 1.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 2.1 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.5 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 1.5 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 1.1 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.8 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.7 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.9 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 2.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.6 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.6 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.6 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.3 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 1.2 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.4 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.4 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.4 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.2 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.5 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.2 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.2 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.6 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.2 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.2 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.1 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.4 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1