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avrg: GFI1 WT vs 36n/n vs KD

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Results for Obox1

Z-value: 1.23

Motif logo

Transcription factors associated with Obox1

Gene Symbol Gene ID Gene Info
ENSMUSG00000054310.17 oocyte specific homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Obox1mm39_v1_chr7_+_15246265_152462650.405.0e-01Click!

Activity profile of Obox1 motif

Sorted Z-values of Obox1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_142202642 0.75 ENSMUST00000090127.7
guanylate binding protein 5
chr13_+_55862437 0.74 ENSMUST00000021959.11
thioredoxin domain containing 15
chr11_-_68864666 0.70 ENSMUST00000038644.5
RAN guanine nucleotide release factor
chr11_+_59738866 0.67 ENSMUST00000102695.4
5',3'-nucleotidase, mitochondrial
chr19_-_33567708 0.56 ENSMUST00000112508.9
lipase, member O3
chr12_-_101943134 0.55 ENSMUST00000221227.2
NADH:ubiquinone oxidoreductase subunit B1
chr1_-_135241429 0.54 ENSMUST00000134088.3
ENSMUST00000081104.10
translocase of inner mitochondrial membrane 17a
chr12_-_36206780 0.54 ENSMUST00000223382.2
ENSMUST00000020856.6
basic leucine zipper and W2 domains 2
chr19_-_11618192 0.54 ENSMUST00000112984.4
membrane-spanning 4-domains, subfamily A, member 3
chr19_-_11618165 0.51 ENSMUST00000186023.7
membrane-spanning 4-domains, subfamily A, member 3
chr17_+_24937062 0.50 ENSMUST00000152407.8
ribosomal protein S2
chr11_+_109540201 0.50 ENSMUST00000106677.8
protein kinase, cAMP dependent regulatory, type I, alpha
chr16_+_48692976 0.50 ENSMUST00000065666.6
resistin like gamma
chr6_+_58810674 0.48 ENSMUST00000041401.11
hect domain and RLD 3
chr2_-_126342551 0.46 ENSMUST00000129187.2
ATPase, class I, type 8B, member 4
chr17_+_21876498 0.45 ENSMUST00000039726.8
zinc finger protein 983
chr11_-_62172164 0.44 ENSMUST00000072916.5
zinc finger SWIM-type containing 7
chr6_-_113717689 0.44 ENSMUST00000032440.6
SEC13 homolog, nuclear pore and COPII coat complex component
chr3_+_142406787 0.43 ENSMUST00000106218.8
kynurenine aminotransferase 3
chr11_-_116164928 0.43 ENSMUST00000106425.4
signal recognition particle 68
chr14_-_31362835 0.43 ENSMUST00000167066.8
ENSMUST00000127204.9
2-hydroxyacyl-CoA lyase 1
chr3_+_142406827 0.43 ENSMUST00000044392.11
ENSMUST00000199519.5
kynurenine aminotransferase 3
chr7_+_46496929 0.43 ENSMUST00000132157.2
ENSMUST00000210631.2
lactate dehydrogenase A
chr6_-_129599645 0.42 ENSMUST00000032252.8
killer cell lectin-like receptor subfamily K, member 1
chr9_-_106768601 0.42 ENSMUST00000069036.14
mesencephalic astrocyte-derived neurotrophic factor
chr11_-_88742285 0.41 ENSMUST00000107903.8
A kinase (PRKA) anchor protein 1
chr19_-_10079091 0.41 ENSMUST00000025567.9
fatty acid desaturase 2
chr18_+_24122689 0.40 ENSMUST00000074941.8
zinc finger protein 35
chr11_-_82799186 0.40 ENSMUST00000103213.10
notchless homolog 1
chr10_-_128640232 0.40 ENSMUST00000051011.14
transmembrane protein 198b
chr7_+_142606476 0.40 ENSMUST00000037941.10
CD81 antigen
chr3_+_32760447 0.40 ENSMUST00000194781.6
actin-like 6A
chr14_+_31888061 0.40 ENSMUST00000164341.2
nuclear receptor coactivator 4
chr15_+_76227695 0.39 ENSMUST00000023210.8
ENSMUST00000231045.2
cytochrome c-1
chr2_+_19376447 0.39 ENSMUST00000023856.9
methionine sulfoxide reductase B2
chr2_+_144435974 0.39 ENSMUST00000136628.2
small integral membrane protein 26
chr12_-_13299197 0.38 ENSMUST00000071103.10
DEAD box helicase 1
chr15_+_72962241 0.37 ENSMUST00000089765.9
ENSMUST00000134353.2
chromatin accessibility complex 1
chr1_-_60137294 0.37 ENSMUST00000141417.3
ENSMUST00000122038.8
WD repeat domain 12
chr7_+_18883647 0.36 ENSMUST00000049294.4
small nuclear ribonucleoprotein D2
chr11_+_95275458 0.36 ENSMUST00000021243.16
ENSMUST00000146556.2
solute carrier family 35, member B1
chr11_+_95925711 0.36 ENSMUST00000006217.10
ENSMUST00000107700.4
SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)
chr7_-_24287037 0.36 ENSMUST00000094705.3
zinc finger protein 575
chr8_-_4829519 0.36 ENSMUST00000022945.9
Shc SH2-domain binding protein 1
chr11_+_29668563 0.36 ENSMUST00000060992.6
reticulon 4
chr11_-_53321242 0.35 ENSMUST00000109019.8
ubiquinol-cytochrome c reductase, complex III subunit VII
chr18_+_67338437 0.34 ENSMUST00000210564.3
charged multivesicular body protein 1B
chr7_+_16186704 0.34 ENSMUST00000019302.10
transmembrane protein 160
chrX_+_158155171 0.34 ENSMUST00000087143.7
eukaryotic translation initiation factor 1A, X-linked
chr10_+_61531282 0.34 ENSMUST00000020284.5
trypsin domain containing 1
chr1_-_10108325 0.33 ENSMUST00000027050.10
ENSMUST00000188619.2
COP9 signalosome subunit 5
chr14_+_55129950 0.33 ENSMUST00000140691.8
poly(A) binding protein, nuclear 1
chr10_-_75616788 0.33 ENSMUST00000173512.2
ENSMUST00000173537.2
predicted gene 20441
glutathione S-transferase, theta 3
chr16_+_33614378 0.32 ENSMUST00000115044.8
mucin 13, epithelial transmembrane
chrX_-_101232978 0.32 ENSMUST00000033683.8
ribosomal protein S4, X-linked
chr19_-_10859046 0.32 ENSMUST00000128835.8
transmembrane protein 109
chr19_+_32573182 0.31 ENSMUST00000235594.2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr10_+_79977291 0.31 ENSMUST00000105367.8
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
chrX_+_133618693 0.31 ENSMUST00000113201.8
ENSMUST00000051256.10
ENSMUST00000113199.8
ENSMUST00000035748.14
ENSMUST00000113198.8
ENSMUST00000113197.2
armadillo repeat containing, X-linked 1
chr11_-_116165024 0.31 ENSMUST00000021133.16
signal recognition particle 68
chr19_+_24853039 0.31 ENSMUST00000073080.7
predicted gene 10053
chr1_-_60137263 0.31 ENSMUST00000143342.8
WD repeat domain 12
chr7_+_81412695 0.31 ENSMUST00000133034.2
RNA guanine-7 methyltransferase activating subunit
chr9_+_73020708 0.30 ENSMUST00000169399.8
ENSMUST00000034738.14
ribosomal L24 domain containing 1
chr11_-_120687195 0.30 ENSMUST00000143139.8
ENSMUST00000129955.2
ENSMUST00000026151.11
ENSMUST00000167023.8
ENSMUST00000106133.8
ENSMUST00000106135.8
dihydrouridine synthase 1-like (S. cerevisiae)
chr11_-_86148379 0.29 ENSMUST00000132024.8
ENSMUST00000139285.8
integrator complex subunit 2
chr17_-_26016039 0.29 ENSMUST00000165838.9
ENSMUST00000002344.7
meteorin, glial cell differentiation regulator
chr3_-_108053396 0.29 ENSMUST00000000001.5
guanine nucleotide binding protein (G protein), alpha inhibiting 3
chr11_-_69470139 0.29 ENSMUST00000048139.12
WD repeat containing, antisense to Trp53
chr13_+_41169740 0.29 ENSMUST00000021790.7
transmembrane protein 14C
chr12_-_108859123 0.29 ENSMUST00000161154.2
ENSMUST00000161410.8
tryptophanyl-tRNA synthetase
chr7_-_113875261 0.28 ENSMUST00000135570.8
proteasome subunit alpha 1
chr5_-_137530214 0.28 ENSMUST00000140139.2
guanine nucleotide binding protein (G protein), beta 2
chr1_-_153425791 0.28 ENSMUST00000041874.9
N-acetylneuraminate pyruvate lyase
chr18_-_66155651 0.27 ENSMUST00000143990.2
lectin, mannose-binding, 1
chr4_-_75196485 0.27 ENSMUST00000030103.9
distal membrane arm assembly complex 1
chr13_-_99481160 0.27 ENSMUST00000022153.8
pentatricopeptide repeat domain 2
chr9_-_57375269 0.27 ENSMUST00000215059.2
ENSMUST00000046587.8
ENSMUST00000214256.2
secretory carrier membrane protein 5
chr4_+_119052548 0.27 ENSMUST00000106345.3
small vasohibin binding protein
chr7_+_133311062 0.27 ENSMUST00000033282.5
BRCA2 and CDKN1A interacting protein
chr2_-_23939401 0.27 ENSMUST00000051416.12
histamine N-methyltransferase
chr7_+_81412673 0.27 ENSMUST00000042166.11
RNA guanine-7 methyltransferase activating subunit
chr4_+_116876597 0.26 ENSMUST00000106448.9
ENSMUST00000106447.9
eukaryotic translation initiation factor 2B, subunit 3
chr13_-_54616618 0.26 ENSMUST00000026990.6
THO complex 3
chr16_-_30900181 0.26 ENSMUST00000055389.9
xyloside xylosyltransferase 1
chr9_-_53521585 0.26 ENSMUST00000034547.6
acetyl-Coenzyme A acetyltransferase 1
chr1_-_53391778 0.25 ENSMUST00000236737.2
ENSMUST00000027264.10
ENSMUST00000123519.9
predicted gene, 50478
asparagine synthetase domain containing 1
chr4_+_101504938 0.25 ENSMUST00000106927.2
leptin receptor overlapping transcript
chr14_+_52348396 0.25 ENSMUST00000111600.11
retinitis pigmentosa GTPase regulator interacting protein 1
chr16_-_91525655 0.25 ENSMUST00000117644.8
crystallin, zeta (quinone reductase)-like 1
chr5_+_21942139 0.25 ENSMUST00000030882.12
peptidase (mitochondrial processing) beta
chr15_+_81548090 0.25 ENSMUST00000023029.15
ENSMUST00000174229.8
ENSMUST00000172748.8
L3MBTL2 polycomb repressive complex 1 subunit
chr16_+_31241085 0.24 ENSMUST00000089759.9
3-hydroxybutyrate dehydrogenase, type 1
chr7_-_44635740 0.24 ENSMUST00000209056.3
ENSMUST00000209124.2
ENSMUST00000208312.2
ENSMUST00000207659.2
ENSMUST00000045325.14
protein arginine N-methyltransferase 1
chr5_-_134643805 0.24 ENSMUST00000202085.2
ENSMUST00000036362.13
ENSMUST00000077636.8
linker for activation of T cells family, member 2
chr5_-_65248927 0.23 ENSMUST00000043352.8
transmembrane protein 156
chr1_+_163889713 0.22 ENSMUST00000097491.10
selectin, lymphocyte
chr16_+_33614715 0.22 ENSMUST00000023520.7
mucin 13, epithelial transmembrane
chr11_+_3913970 0.22 ENSMUST00000109985.8
ENSMUST00000020705.5
pescadillo ribosomal biogenesis factor 1
chrY_+_1010543 0.21 ENSMUST00000091197.4
eukaryotic translation initiation factor 2, subunit 3, structural gene Y-linked
chr14_-_70043079 0.21 ENSMUST00000022665.4
Rho-related BTB domain containing 2
chrX_+_141010919 0.21 ENSMUST00000042329.12
nuclear transport factor 2-like export factor 2
chr2_+_181506130 0.21 ENSMUST00000039551.9
polymerase (RNA) III (DNA directed) polypeptide K
chr15_+_100659622 0.20 ENSMUST00000023776.13
solute carrier family 4 (anion exchanger), member 8
chr3_-_63872189 0.20 ENSMUST00000029402.15
solute carrier family 33 (acetyl-CoA transporter), member 1
chr15_+_97682210 0.20 ENSMUST00000117892.2
ENSMUST00000229084.2
solute carrier family 48 (heme transporter), member 1
chr15_-_83006957 0.20 ENSMUST00000018184.10
ribosomal RNA processing 7 homolog A
chr7_+_37883300 0.19 ENSMUST00000179992.10
RIKEN cDNA 1600014C10 gene
chr13_-_98628509 0.19 ENSMUST00000170205.2
predicted pseudogene 10320
chr18_-_32044877 0.19 ENSMUST00000054984.8
SFT2 domain containing 3
chr8_+_114860375 0.19 ENSMUST00000147605.8
ENSMUST00000134593.2
nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr16_-_91525863 0.19 ENSMUST00000073466.13
crystallin, zeta (quinone reductase)-like 1
chr11_+_115044966 0.19 ENSMUST00000021076.6
RAB37, member RAS oncogene family
chr15_-_76544308 0.19 ENSMUST00000066677.10
ENSMUST00000177359.2
cysteine and histidine rich 1
chr4_+_155789246 0.19 ENSMUST00000030905.9
Ssu72 RNA polymerase II CTD phosphatase homolog (yeast)
chr9_-_21223551 0.19 ENSMUST00000003397.9
ENSMUST00000213250.2
adaptor protein complex AP-1, mu 2 subunit
chr1_-_52271455 0.18 ENSMUST00000114512.8
glutaminase
chr5_-_137529465 0.18 ENSMUST00000150063.9
guanine nucleotide binding protein (G protein), beta 2
chr7_-_113875342 0.18 ENSMUST00000033008.10
proteasome subunit alpha 1
chr17_-_35265702 0.18 ENSMUST00000097338.11
mutS homolog 5
chr17_-_35984625 0.18 ENSMUST00000001565.15
general transcription factor II H, polypeptide 4
chr2_-_86109346 0.17 ENSMUST00000217294.2
ENSMUST00000217245.2
ENSMUST00000216432.2
olfactory receptor 1051
chr16_+_55786638 0.17 ENSMUST00000023269.5
ribosomal protein L24
chr9_+_62249730 0.17 ENSMUST00000156461.2
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr17_+_26780453 0.17 ENSMUST00000167662.8
endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
chr18_+_31922173 0.17 ENSMUST00000025106.5
ENSMUST00000234146.2
polymerase (RNA) II (DNA directed) polypeptide D
chr10_-_117582259 0.17 ENSMUST00000079041.7
solute carrier family 35, member E3
chr11_-_30599510 0.17 ENSMUST00000074613.4
acylphosphatase 2, muscle type
chr6_-_69282389 0.17 ENSMUST00000103350.3
immunoglobulin kappa variable 4-68
chr2_-_28511941 0.16 ENSMUST00000028156.8
ENSMUST00000164290.8
growth factor independent 1B
chr14_-_20027112 0.16 ENSMUST00000159028.8
guanine nucleotide binding protein (G protein), gamma 2
chr2_-_152185901 0.16 ENSMUST00000040312.7
tribbles pseudokinase 3
chr11_+_69886652 0.16 ENSMUST00000101526.9
PHD finger protein 23
chr19_-_6919755 0.16 ENSMUST00000099782.10
G protein-coupled receptor 137
chr7_+_88079465 0.15 ENSMUST00000107256.4
RAB38, member RAS oncogene family
chr16_-_17906886 0.15 ENSMUST00000132241.2
ENSMUST00000139861.2
ENSMUST00000003620.13
proline dehydrogenase
chrX_-_52645649 0.15 ENSMUST00000088779.5
retrotransposon Gag like 8A
chr5_+_124690908 0.15 ENSMUST00000071057.14
ENSMUST00000111438.2
DEAD box helicase 55
chr7_+_101871623 0.15 ENSMUST00000143541.8
post-GPI attachment to proteins 2
chr11_+_4852212 0.15 ENSMUST00000142543.3
THO complex 5
chr9_+_62249341 0.14 ENSMUST00000135395.8
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr16_+_35861554 0.14 ENSMUST00000042203.10
WD repeat domain 5B
chr14_+_59438658 0.14 ENSMUST00000173547.8
ENSMUST00000043227.13
ENSMUST00000022551.14
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
chr11_+_23616007 0.14 ENSMUST00000058163.11
pseudouridylate synthase 10
chr11_-_59937302 0.14 ENSMUST00000000310.14
ENSMUST00000102693.9
ENSMUST00000148512.2
phosphatidylethanolamine N-methyltransferase
chr1_+_134487893 0.14 ENSMUST00000047714.14
lysine (K)-specific demethylase 5B
chr15_+_76579960 0.14 ENSMUST00000229679.2
glutamic pyruvic transaminase, soluble
chr3_+_151143557 0.14 ENSMUST00000196970.3
adhesion G protein-coupled receptor L4
chr17_-_12726591 0.14 ENSMUST00000024595.4
solute carrier family 22 (organic cation transporter), member 3
chr19_-_6178171 0.14 ENSMUST00000154601.8
ENSMUST00000138931.3
sorting nexin 15
chr8_+_79236051 0.14 ENSMUST00000209992.2
solute carrier family 10 (sodium/bile acid cotransporter family), member 7
chr7_-_44635813 0.13 ENSMUST00000208829.2
ENSMUST00000207370.2
ENSMUST00000107843.11
protein arginine N-methyltransferase 1
chr11_+_6242555 0.13 ENSMUST00000081894.5
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr4_-_116982804 0.13 ENSMUST00000183310.2
BTB (POZ) domain containing 19
chr8_-_84184978 0.13 ENSMUST00000081506.11
short coiled-coil protein
chr5_-_65248962 0.13 ENSMUST00000212080.2
transmembrane protein 156
chr11_-_86148344 0.13 ENSMUST00000136469.2
ENSMUST00000018212.13
integrator complex subunit 2
chr12_-_102390000 0.13 ENSMUST00000110020.8
legumain
chr2_-_34803988 0.13 ENSMUST00000028232.7
ENSMUST00000202907.2
PHD finger protein 19
chr17_+_36132567 0.13 ENSMUST00000003635.7
immediate early response 3
chr2_+_83786037 0.13 ENSMUST00000179192.2
predicted gene 13698
chr11_+_23616477 0.13 ENSMUST00000143117.2
pseudouridylate synthase 10
chr1_-_139708906 0.12 ENSMUST00000111986.8
ENSMUST00000027612.11
ENSMUST00000111989.9
complement factor H-related 4
chr3_-_63872079 0.12 ENSMUST00000161659.8
solute carrier family 33 (acetyl-CoA transporter), member 1
chr16_-_18161746 0.11 ENSMUST00000231372.2
ENSMUST00000130752.2
ENSMUST00000231605.2
ENSMUST00000115628.10
transport and golgi organization 2
chr13_+_58550499 0.11 ENSMUST00000225815.2
RecQ mediated genome instability 1
chr11_-_5657658 0.11 ENSMUST00000154330.2
mitochondrial ribosomal protein S24
chr11_-_79145489 0.11 ENSMUST00000017821.12
WD repeat and SOCS box-containing 1
chr10_-_79875479 0.11 ENSMUST00000004786.10
polymerase (RNA) II (DNA directed) polypeptide E
chr10_+_94034817 0.11 ENSMUST00000020209.16
ENSMUST00000179990.8
NADH:ubiquinone oxidoreductase subunit A12
chrX_-_84820250 0.11 ENSMUST00000113978.9
glycerol kinase
chr5_+_143450329 0.11 ENSMUST00000045593.12
diacylglycerol lipase, beta
chr11_-_102120917 0.10 ENSMUST00000008999.12
histone deacetylase 5
chr6_-_124710084 0.10 ENSMUST00000112484.10
protein tyrosine phosphatase, non-receptor type 6
chr6_+_124908341 0.10 ENSMUST00000203021.3
myeloid leukemia factor 2
chr2_-_87902174 0.10 ENSMUST00000215268.2
olfactory receptor 1163
chr7_+_27198740 0.10 ENSMUST00000098644.9
ENSMUST00000108355.2
ENSMUST00000238936.2
periaxin
chr17_+_66418525 0.10 ENSMUST00000072383.14
WASH complex subunit 1
chr12_+_86725459 0.10 ENSMUST00000021681.4
vasohibin 1
chr1_+_173248104 0.10 ENSMUST00000173023.2
absent in melanoma 2
chr6_+_129385816 0.10 ENSMUST00000058352.15
ENSMUST00000088075.8
C-type lectin domain family 9, member a
chr13_-_74918701 0.10 ENSMUST00000223126.2
calpastatin
chr13_+_99481283 0.10 ENSMUST00000052249.7
ENSMUST00000224660.3
mitochondrial ribosomal protein S27
chr16_+_87251852 0.10 ENSMUST00000119504.8
ENSMUST00000131356.8
ubiquitin specific peptidase 16
chr11_+_96355413 0.09 ENSMUST00000103154.11
ENSMUST00000100521.10
ENSMUST00000100519.11
src family associated phosphoprotein 1
chr11_-_102120953 0.09 ENSMUST00000107150.8
ENSMUST00000156337.2
ENSMUST00000107151.9
ENSMUST00000107152.9
histone deacetylase 5
chr9_+_38630317 0.09 ENSMUST00000129598.2
von Willebrand factor A domain containing 5A
chr12_+_21366386 0.09 ENSMUST00000076813.8
ENSMUST00000221693.2
ENSMUST00000223345.2
ENSMUST00000222344.2
isoamyl acetate-hydrolyzing esterase 1 homolog
chr8_-_104975134 0.09 ENSMUST00000212275.2
ENSMUST00000050211.7
thymidine kinase 2, mitochondrial
chr18_-_13013030 0.09 ENSMUST00000119512.8
oxysterol binding protein-like 1A
chr7_+_44033520 0.08 ENSMUST00000118962.8
ENSMUST00000118831.8
synaptotagmin III
chr16_-_16687119 0.08 ENSMUST00000075017.5
pre-B lymphocyte gene 1
chr13_-_64514830 0.08 ENSMUST00000222971.2
cathepsin L
chr1_+_165130192 0.08 ENSMUST00000111450.3
G protein-coupled receptor 161
chr10_-_83369994 0.08 ENSMUST00000020497.14
aldehyde dehydrogenase 1 family, member L2
chr16_+_38383154 0.08 ENSMUST00000171687.8
ENSMUST00000002924.15
transmembrane protein 39a
chr7_+_81220987 0.08 ENSMUST00000165460.2
WAS protein homolog associated with actin, golgi membranes and microtubules
chr13_-_69147639 0.08 ENSMUST00000022013.8
adenylate cyclase 2
chr4_-_42528175 0.08 ENSMUST00000180201.2
family with sequence similarity 205, member A2
chr4_-_117013396 0.08 ENSMUST00000102696.5
ribosomal protein S8

Network of associatons between targets according to the STRING database.

First level regulatory network of Obox1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0006244 pyrimidine nucleotide catabolic process(GO:0006244) pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.2 0.5 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.1 0.4 GO:0030887 positive regulation of myeloid dendritic cell activation(GO:0030887)
0.1 0.4 GO:0002014 vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure(GO:0002014)
0.1 0.5 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.1 0.4 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.1 0.4 GO:0030091 protein repair(GO:0030091)
0.1 0.4 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.1 0.3 GO:0006550 isoleucine catabolic process(GO:0006550)
0.1 0.2 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.1 0.3 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.1 0.4 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.1 0.3 GO:0050428 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.1 0.7 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.1 1.0 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 0.7 GO:1900227 positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.1 0.4 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.1 0.3 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1 0.5 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.1 0.9 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1 0.3 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.1 0.9 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 0.4 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 0.2 GO:0031990 mRNA export from nucleus in response to heat stress(GO:0031990)
0.1 0.9 GO:0070189 kynurenine metabolic process(GO:0070189)
0.1 0.3 GO:0001692 histamine metabolic process(GO:0001692)
0.1 0.2 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.4 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 0.4 GO:0019661 glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.0 0.4 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.3 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.4 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.4 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.5 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.3 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.3 GO:0090666 telomere assembly(GO:0032202) scaRNA localization to Cajal body(GO:0090666)
0.0 0.1 GO:2000864 estradiol secretion(GO:0035938) regulation of estradiol secretion(GO:2000864)
0.0 0.5 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.1 GO:0006624 vacuolar protein processing(GO:0006624)
0.0 0.2 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.2 GO:1903232 platelet dense granule organization(GO:0060155) phagosome acidification(GO:0090383) melanosome assembly(GO:1903232)
0.0 0.5 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.3 GO:1903894 regulation of IRE1-mediated unfolded protein response(GO:1903894)
0.0 0.5 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.1 GO:0046104 thymidine metabolic process(GO:0046104)
0.0 0.2 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.2 GO:0015886 heme transport(GO:0015886)
0.0 0.4 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:0009258 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.0 0.1 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.0 0.4 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.3 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.1 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.0 0.5 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.4 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:0070537 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522) histone H2A K63-linked deubiquitination(GO:0070537)
0.0 0.2 GO:0051572 negative regulation of histone H3-K4 methylation(GO:0051572)
0.0 0.3 GO:0061101 neuroendocrine cell differentiation(GO:0061101)
0.0 0.4 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.3 GO:0039702 viral budding via host ESCRT complex(GO:0039702) regulation of mitotic spindle assembly(GO:1901673)
0.0 0.2 GO:0061034 succinyl-CoA metabolic process(GO:0006104) olfactory bulb mitral cell layer development(GO:0061034)
0.0 0.1 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 0.1 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.0 0.1 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822)
0.0 0.1 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.0 0.1 GO:0090472 dibasic protein processing(GO:0090472)
0.0 0.1 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.0 0.4 GO:0006353 DNA-templated transcription, termination(GO:0006353)
0.0 0.1 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.0 0.0 GO:0014732 skeletal muscle atrophy(GO:0014732)
0.0 0.1 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.0 0.1 GO:0009786 regulation of asymmetric cell division(GO:0009786) mesonephric duct formation(GO:0072181)
0.0 0.1 GO:1904109 polar body extrusion after meiotic divisions(GO:0040038) spindle assembly involved in meiosis(GO:0090306) positive regulation of cholesterol import(GO:1904109) positive regulation of sterol import(GO:2000911)
0.0 0.1 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.1 GO:1990743 protein sialylation(GO:1990743)
0.0 0.1 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.0 0.2 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 0.2 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.1 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.1 GO:1902996 regulation of neuronal signal transduction(GO:1902847) neurofibrillary tangle assembly(GO:1902988) regulation of neurofibrillary tangle assembly(GO:1902996) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0 0.3 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0000814 ESCRT II complex(GO:0000814)
0.1 0.4 GO:0071920 cleavage body(GO:0071920)
0.1 0.9 GO:0070545 PeBoW complex(GO:0070545)
0.1 1.0 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.1 0.7 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.1 0.5 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1 0.2 GO:0034456 CURI complex(GO:0032545) UTP-C complex(GO:0034456)
0.1 0.8 GO:0034709 methylosome(GO:0034709)
0.0 0.4 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.2 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.0 0.4 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.5 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.3 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.3 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.2 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.2 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.4 GO:0044754 autolysosome(GO:0044754)
0.0 0.1 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 0.4 GO:0032039 integrator complex(GO:0032039)
0.0 0.2 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.4 GO:0031011 Ino80 complex(GO:0031011)
0.0 0.2 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.4 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.3 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.4 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.1 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0 0.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.3 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 0.3 GO:0019908 nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0 0.3 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0047804 cysteine-S-conjugate beta-lyase activity(GO:0047804)
0.1 0.4 GO:0032394 MHC class Ib receptor activity(GO:0032394)
0.1 0.7 GO:0005047 signal recognition particle binding(GO:0005047) endoplasmic reticulum signal peptide binding(GO:0030942)
0.1 0.4 GO:0030519 snoRNP binding(GO:0030519)
0.1 0.4 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 0.7 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.1 0.2 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1 0.3 GO:0004020 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.1 0.3 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 0.3 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.1 0.3 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.1 0.2 GO:0036461 BLOC-2 complex binding(GO:0036461)
0.1 0.4 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 0.3 GO:0051185 coenzyme transporter activity(GO:0051185)
0.1 0.3 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.1 0.6 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.4 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768)
0.0 0.2 GO:0033677 DNA/RNA helicase activity(GO:0033677)
0.0 0.3 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.3 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.0 0.2 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.4 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.3 GO:0016453 acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.0 0.3 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.5 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.2 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.2 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.0 0.2 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.4 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 0.4 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.7 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.4 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.1 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.0 0.1 GO:0005329 dopamine transmembrane transporter activity(GO:0005329)
0.0 0.1 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.1 GO:0004021 L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.5 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.3 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.1 GO:0030984 kininogen binding(GO:0030984)
0.0 0.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.3 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.1 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.0 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.4 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.2 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.7 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.9 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.5 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 0.1 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.8 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.3 GO:0051861 glycolipid binding(GO:0051861)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.3 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.3 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.4 PID MYC PATHWAY C-MYC pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.7 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.4 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 1.2 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.6 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 1.2 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.3 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.4 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.4 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 1.0 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.3 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 1.0 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.3 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.0 0.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.4 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.7 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling