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avrg: GFI1 WT vs 36n/n vs KD

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Results for Pax1_Pax9

Z-value: 0.64

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Transcription factors associated with Pax1_Pax9

Gene Symbol Gene ID Gene Info
Pax1
ENSMUSG00000037034.17 paired box 1
Pax9
ENSMUSG00000001497.19 paired box 9

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pax1mm39_v1_chr2_+_147206910_147206931-0.672.2e-01Click!
Pax9mm39_v1_chr12_+_56742413_56742459-0.503.9e-01Click!

Activity profile of Pax1_Pax9 motif

Sorted Z-values of Pax1_Pax9 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_28128180 0.40 ENSMUST00000114848.8
Taf11
TATA-box binding protein associated factor 11
chr8_+_31640332 0.32 ENSMUST00000209851.2
ENSMUST00000098842.3
ENSMUST00000210129.2
Tti2
TELO2 interacting protein 2
chr17_-_75858835 0.32 ENSMUST00000234785.2
ENSMUST00000112507.4
Fam98a
family with sequence similarity 98, member A
chr7_-_23998735 0.25 ENSMUST00000145131.8
Zfp61
zinc finger protein 61
chr5_+_129864044 0.21 ENSMUST00000201414.5
Cct6a
chaperonin containing Tcp1, subunit 6a (zeta)
chr8_-_95564881 0.17 ENSMUST00000034233.15
ENSMUST00000162538.9
Ciapin1
cytokine induced apoptosis inhibitor 1
chr5_-_31448370 0.15 ENSMUST00000041565.11
ENSMUST00000201809.2
Ift172
intraflagellar transport 172
chr4_+_11558905 0.15 ENSMUST00000095145.12
ENSMUST00000108306.9
ENSMUST00000070755.13
Rad54b
RAD54 homolog B (S. cerevisiae)
chr7_+_48438751 0.15 ENSMUST00000118927.8
ENSMUST00000125280.8
Zdhhc13
zinc finger, DHHC domain containing 13
chr2_-_62242562 0.12 ENSMUST00000047812.8
Dpp4
dipeptidylpeptidase 4
chr17_+_28128307 0.09 ENSMUST00000233525.2
ENSMUST00000025058.15
ENSMUST00000233866.2
Anks1
ankyrin repeat and SAM domain containing 1
chr17_+_28128250 0.08 ENSMUST00000114842.9
ENSMUST00000088027.7
Anks1
ankyrin repeat and SAM domain containing 1
chr18_+_69477541 0.08 ENSMUST00000114985.10
ENSMUST00000128706.8
ENSMUST00000201781.4
ENSMUST00000202674.4
Tcf4
transcription factor 4
chr9_+_21249118 0.08 ENSMUST00000034697.8
Slc44a2
solute carrier family 44, member 2
chr1_+_87683592 0.07 ENSMUST00000144047.8
ENSMUST00000027512.13
ENSMUST00000113186.8
ENSMUST00000113190.3
Atg16l1
autophagy related 16-like 1 (S. cerevisiae)
chr13_-_62668265 0.06 ENSMUST00000082203.7
Zfp934
zinc finger protein 934
chr8_+_95564949 0.06 ENSMUST00000034234.15
ENSMUST00000159871.4
Coq9
coenzyme Q9
chr9_-_96993169 0.05 ENSMUST00000085206.11
Slc25a36
solute carrier family 25, member 36
chr9_+_96078299 0.04 ENSMUST00000165120.9
Tfdp2
transcription factor Dp 2
chr2_+_84564394 0.04 ENSMUST00000238573.2
ENSMUST00000090729.9
Ypel4
yippee like 4
chr19_-_6973393 0.04 ENSMUST00000041686.10
ENSMUST00000180765.2
Nudt22
nudix (nucleoside diphosphate linked moiety X)-type motif 22
chr14_+_31058589 0.03 ENSMUST00000022451.14
Capn7
calpain 7
chr5_-_129864202 0.02 ENSMUST00000136507.4
Psph
phosphoserine phosphatase
chr2_-_111100733 0.02 ENSMUST00000099619.6
Olfr1277
olfactory receptor 1277
chr4_-_117232650 0.01 ENSMUST00000094853.9
Rnf220
ring finger protein 220
chr2_+_177834868 0.01 ENSMUST00000103065.2
Phactr3
phosphatase and actin regulator 3
chr10_+_75409282 0.01 ENSMUST00000006508.10
Ggt1
gamma-glutamyltransferase 1
chr2_+_85612365 0.01 ENSMUST00000215945.2
Olfr1015
olfactory receptor 1015
chr9_-_22300409 0.01 ENSMUST00000040912.9
Anln
anillin, actin binding protein
chrX_+_73356597 0.01 ENSMUST00000114160.2
Fam50a
family with sequence similarity 50, member A
chr5_+_112403678 0.01 ENSMUST00000031286.13
ENSMUST00000131673.8
ENSMUST00000112375.2
Crybb1
crystallin, beta B1
chr14_+_32938774 0.01 ENSMUST00000111956.9
Arhgap22
Rho GTPase activating protein 22
chr19_+_13140364 0.00 ENSMUST00000207113.3
Olfr1461
olfactory receptor 1461
chr7_+_118232952 0.00 ENSMUST00000057320.8
Tmc5
transmembrane channel-like gene family 5
chr17_-_45912993 0.00 ENSMUST00000178858.3
Mymx
myomixer, myoblast fusion factor

Network of associatons between targets according to the STRING database.

First level regulatory network of Pax1_Pax9

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0036343 psychomotor behavior(GO:0036343)
0.0 0.1 GO:0061739 protein lipidation involved in autophagosome assembly(GO:0061739)
0.0 0.4 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.2 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.0 0.2 GO:1904869 protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.0 0.3 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.1 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.2 GO:0005832 chaperonin-containing T-complex(GO:0005832)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 0.4 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.2 GO:0015616 DNA translocase activity(GO:0015616)