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avrg: GFI1 WT vs 36n/n vs KD

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Results for Phox2a

Z-value: 0.91

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Transcription factors associated with Phox2a

Gene Symbol Gene ID Gene Info
Phox2a
ENSMUSG00000007946.12 paired-like homeobox 2a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Phox2amm39_v1_chr7_+_101467512_1014675290.583.0e-01Click!

Activity profile of Phox2a motif

Sorted Z-values of Phox2a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_89855921 1.70 ENSMUST00000216616.3
Olfr1264
olfactory receptor 1264
chr9_+_118892497 1.34 ENSMUST00000141185.8
ENSMUST00000126251.8
ENSMUST00000136561.2
Vill
villin-like
chrX_+_16485937 0.85 ENSMUST00000026013.6
Maoa
monoamine oxidase A
chr2_-_111843053 0.84 ENSMUST00000213559.3
Olfr1310
olfactory receptor 1310
chrM_+_2743 0.81 ENSMUST00000082392.1
mt-Nd1
mitochondrially encoded NADH dehydrogenase 1
chr2_-_111820618 0.78 ENSMUST00000216948.2
ENSMUST00000214935.2
ENSMUST00000217452.2
ENSMUST00000215045.2
Olfr1309
olfactory receptor 1309
chr1_+_173983199 0.65 ENSMUST00000213748.2
Olfr420
olfactory receptor 420
chr2_-_34990689 0.47 ENSMUST00000226631.2
ENSMUST00000045776.5
ENSMUST00000226972.2
AI182371
expressed sequence AI182371
chr15_-_66985760 0.46 ENSMUST00000092640.6
St3gal1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr19_+_12364643 0.41 ENSMUST00000217062.3
ENSMUST00000216145.2
ENSMUST00000213657.2
Olfr1440
olfactory receptor 1440
chr7_-_12829100 0.25 ENSMUST00000209822.3
ENSMUST00000235753.2
Vmn1r85
vomeronasal 1 receptor 85
chr4_+_134658209 0.23 ENSMUST00000030622.3
Syf2
SYF2 homolog, RNA splicing factor (S. cerevisiae)
chr11_-_99134885 0.23 ENSMUST00000103132.10
ENSMUST00000038214.7
Krt222
keratin 222
chrX_+_159551009 0.22 ENSMUST00000033650.14
Rs1
retinoschisis (X-linked, juvenile) 1 (human)
chr7_-_44753168 0.19 ENSMUST00000211085.2
ENSMUST00000210642.2
ENSMUST00000003512.9
Fcgrt
Fc fragment of IgG receptor and transporter
chr15_+_98350469 0.17 ENSMUST00000217517.2
Olfr281
olfactory receptor 281
chr4_+_108576846 0.11 ENSMUST00000178992.2
3110021N24Rik
RIKEN cDNA 3110021N24 gene
chr15_+_39522905 0.09 ENSMUST00000226410.2
Rims2
regulating synaptic membrane exocytosis 2
chr7_-_101486983 0.08 ENSMUST00000185929.2
ENSMUST00000165052.8
Inppl1
inositol polyphosphate phosphatase-like 1
chr11_+_116734104 0.07 ENSMUST00000106370.10
Mettl23
methyltransferase like 23
chr5_+_13448833 0.05 ENSMUST00000137798.10
Sema3a
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr10_-_128885867 0.04 ENSMUST00000216460.2
Olfr765
olfactory receptor 765
chr1_+_173924457 0.03 ENSMUST00000213832.2
Olfr427
olfactory receptor 427
chr6_+_37847721 0.03 ENSMUST00000031859.14
ENSMUST00000120428.8
Trim24
tripartite motif-containing 24
chr5_-_118382926 0.02 ENSMUST00000117177.8
ENSMUST00000133372.2
ENSMUST00000154786.8
ENSMUST00000121369.8
Rnft2
ring finger protein, transmembrane 2
chr10_-_129965752 0.02 ENSMUST00000215217.2
ENSMUST00000214192.2
Olfr824
olfactory receptor 824
chr12_+_30934320 0.01 ENSMUST00000067087.7
Alkal2
ALK and LTK ligand 2
chr8_-_3675024 0.01 ENSMUST00000133459.8
Pcp2
Purkinje cell protein 2 (L7)
chr1_-_154692678 0.01 ENSMUST00000238369.2
Cacna1e
calcium channel, voltage-dependent, R type, alpha 1E subunit
chr6_-_41752111 0.01 ENSMUST00000214976.3
Olfr459
olfactory receptor 459
chr19_-_47680528 0.00 ENSMUST00000026045.14
ENSMUST00000086923.6
Col17a1
collagen, type XVII, alpha 1
chr2_-_164427367 0.00 ENSMUST00000109342.2
Wfdc6a
WAP four-disulfide core domain 6A

Network of associatons between targets according to the STRING database.

First level regulatory network of Phox2a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0042420 dopamine catabolic process(GO:0042420)
0.1 0.2 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.0 0.8 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 1.3 GO:0051693 actin filament capping(GO:0051693)
0.0 0.0 GO:1903375 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) facioacoustic ganglion development(GO:1903375)
0.0 4.1 GO:0050907 detection of chemical stimulus involved in sensory perception(GO:0050907)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.8 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.5 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.2 GO:0019770 IgG receptor activity(GO:0019770)
0.0 0.8 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.5 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis