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avrg: GFI1 WT vs 36n/n vs KD

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Results for Pitx1

Z-value: 0.67

Motif logo

Transcription factors associated with Pitx1

Gene Symbol Gene ID Gene Info
ENSMUSG00000021506.8 paired-like homeodomain transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pitx1mm39_v1_chr13_-_55979191_55979238-0.781.2e-01Click!

Activity profile of Pitx1 motif

Sorted Z-values of Pitx1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_109540201 0.64 ENSMUST00000106677.8
protein kinase, cAMP dependent regulatory, type I, alpha
chr4_-_156340276 0.53 ENSMUST00000220228.2
ENSMUST00000218788.2
ENSMUST00000179919.3
sterile alpha motif domain containing 11
chr10_+_80765900 0.48 ENSMUST00000015456.10
ENSMUST00000220246.2
growth arrest and DNA-damage-inducible 45 beta
chrM_+_8603 0.45 ENSMUST00000082409.1
mitochondrially encoded cytochrome c oxidase III
chr7_+_16515265 0.40 ENSMUST00000108496.9
solute carrier family 1 (neutral amino acid transporter), member 5
chr1_+_177272297 0.36 ENSMUST00000193440.2
zinc finger and BTB domain containing 18
chr17_+_34124078 0.35 ENSMUST00000172817.2
small integral membrane protein 40
chr14_+_26722319 0.35 ENSMUST00000035433.10
homeobox gene expressed in ES cells
chrX_+_168662592 0.35 ENSMUST00000112105.8
ENSMUST00000078947.12
midline 1
chr11_-_68864666 0.32 ENSMUST00000038644.5
RAN guanine nucleotide release factor
chrX_+_133657312 0.32 ENSMUST00000081834.10
ENSMUST00000086880.11
ENSMUST00000086884.5
armadillo repeat containing, X-linked 3
chr1_+_177272215 0.29 ENSMUST00000192851.2
ENSMUST00000193480.2
ENSMUST00000195388.2
zinc finger and BTB domain containing 18
chr8_-_96615138 0.29 ENSMUST00000034097.8
glutamatic-oxaloacetic transaminase 2, mitochondrial
chr9_+_109704609 0.29 ENSMUST00000094324.8
cell division cycle 25A
chr3_+_41517790 0.28 ENSMUST00000163764.8
jade family PHD finger 1
chr11_+_23206001 0.28 ENSMUST00000020538.13
ENSMUST00000109551.8
ENSMUST00000102870.8
ENSMUST00000102869.8
exportin 1
chr14_-_31362835 0.28 ENSMUST00000167066.8
ENSMUST00000127204.9
2-hydroxyacyl-CoA lyase 1
chr5_-_134485430 0.27 ENSMUST00000200944.4
ENSMUST00000202280.4
ENSMUST00000074114.12
ENSMUST00000100654.10
ENSMUST00000100650.10
ENSMUST00000111245.9
ENSMUST00000202554.4
ENSMUST00000073161.12
ENSMUST00000100652.10
ENSMUST00000171794.9
ENSMUST00000167084.9
general transcription factor II I repeat domain-containing 1
chr3_+_41517829 0.27 ENSMUST00000170711.8
jade family PHD finger 1
chrX_+_168468186 0.27 ENSMUST00000112107.8
ENSMUST00000112104.8
midline 1
chr3_+_106020545 0.26 ENSMUST00000079132.12
ENSMUST00000139086.2
chitinase, acidic 1
chr11_+_87938626 0.26 ENSMUST00000107920.10
serine and arginine-rich splicing factor 1
chr19_-_38032006 0.25 ENSMUST00000172095.3
ENSMUST00000041475.16
myoferlin
chr10_-_115198093 0.25 ENSMUST00000219890.2
ENSMUST00000218731.2
ENSMUST00000217887.2
ENSMUST00000092170.7
transmembrane protein 19
chr2_-_23939401 0.25 ENSMUST00000051416.12
histamine N-methyltransferase
chr11_+_3280771 0.24 ENSMUST00000136536.8
ENSMUST00000093399.11
phosphoinositide-3-kinase interacting protein 1
chr2_-_126342551 0.23 ENSMUST00000129187.2
ATPase, class I, type 8B, member 4
chr19_-_4976844 0.23 ENSMUST00000236496.2
dipeptidylpeptidase 3
chr11_+_29668563 0.23 ENSMUST00000060992.6
reticulon 4
chr5_+_75735576 0.22 ENSMUST00000144270.8
ENSMUST00000005815.7
KIT proto-oncogene receptor tyrosine kinase
chr11_+_90078485 0.22 ENSMUST00000124877.3
ENSMUST00000153734.2
ENSMUST00000134929.8
predicted gene 45716
chr19_-_47907705 0.22 ENSMUST00000095998.7
inositol 1,4,5-triphosphate receptor interacting protein
chr18_+_36812246 0.21 ENSMUST00000186538.7
solute carrier family 35, member A4
chr11_-_22932090 0.21 ENSMUST00000160826.2
ENSMUST00000093270.6
ENSMUST00000071068.9
ENSMUST00000159081.8
COMM domain containing 1B
COMM domain containing 1
chr7_-_109092834 0.20 ENSMUST00000106739.8
tripartite motif-containing 66
chr11_-_59078565 0.19 ENSMUST00000170895.3
guanylate kinase 1
chr15_+_80832685 0.19 ENSMUST00000023043.10
ENSMUST00000164806.6
ENSMUST00000207170.2
ENSMUST00000168756.8
adenylosuccinate lyase
chrX_+_73468140 0.19 ENSMUST00000135165.8
ENSMUST00000114128.8
ENSMUST00000004330.10
ENSMUST00000114133.9
ENSMUST00000114129.9
ENSMUST00000132749.2
inhibitor of kappaB kinase gamma
chr5_-_23821523 0.19 ENSMUST00000088392.9
serine/arginine-rich protein specific kinase 2
chr19_-_38031774 0.19 ENSMUST00000226068.2
myoferlin
chrX_-_135642025 0.18 ENSMUST00000155207.8
ENSMUST00000080411.13
ENSMUST00000169418.8
mortality factor 4 like 2
chr19_+_9957940 0.18 ENSMUST00000235196.2
ferritin heavy polypeptide 1
chr6_+_58810674 0.18 ENSMUST00000041401.11
hect domain and RLD 3
chr4_+_102446883 0.18 ENSMUST00000097949.11
ENSMUST00000106901.2
phosphodiesterase 4B, cAMP specific
chr11_+_87938128 0.18 ENSMUST00000139129.9
serine and arginine-rich splicing factor 1
chr11_+_87938519 0.17 ENSMUST00000079866.11
serine and arginine-rich splicing factor 1
chr1_-_171050004 0.17 ENSMUST00000147246.2
ENSMUST00000111326.8
ENSMUST00000138184.8
translocase of outer mitochondrial membrane 40-like
chr5_+_86219593 0.17 ENSMUST00000198435.5
ENSMUST00000031171.9
signal transducing adaptor family member 1
chr3_+_102965910 0.17 ENSMUST00000199367.5
ENSMUST00000199049.5
ENSMUST00000197678.5
neuroblastoma ras oncogene
chr8_+_79236051 0.17 ENSMUST00000209992.2
solute carrier family 10 (sodium/bile acid cotransporter family), member 7
chr10_-_115197775 0.17 ENSMUST00000217848.2
transmembrane protein 19
chr16_-_30900181 0.16 ENSMUST00000055389.9
xyloside xylosyltransferase 1
chr7_-_25098122 0.16 ENSMUST00000105177.3
ENSMUST00000149349.2
lipase, hormone sensitive
chr8_+_85786684 0.16 ENSMUST00000095220.4
F-box and WD-40 domain protein 9
chr1_-_80255156 0.16 ENSMUST00000168372.2
cullin 3
chr9_-_108443916 0.16 ENSMUST00000194381.2
NADH:ubiquinone oxidoreductase complex assembly factor 3
chrX_-_135877607 0.16 ENSMUST00000127404.8
ENSMUST00000113071.2
thymosin beta 15b like
thymosin beta 15b1
chrX_+_20291927 0.15 ENSMUST00000115384.9
jade family PHD finger 3
chr11_+_95275458 0.14 ENSMUST00000021243.16
ENSMUST00000146556.2
solute carrier family 35, member B1
chrX_-_135641869 0.14 ENSMUST00000166930.8
ENSMUST00000113095.8
mortality factor 4 like 2
chr5_-_125371162 0.14 ENSMUST00000127148.2
scavenger receptor class B, member 1
chr14_+_52348396 0.14 ENSMUST00000111600.11
retinitis pigmentosa GTPase regulator interacting protein 1
chr1_-_171050077 0.14 ENSMUST00000005817.9
translocase of outer mitochondrial membrane 40-like
chr7_-_4517367 0.13 ENSMUST00000166161.8
troponin T1, skeletal, slow
chr11_+_19874403 0.13 ENSMUST00000093298.12
sprouty-related EVH1 domain containing 2
chr3_+_136375839 0.12 ENSMUST00000070198.14
protein phosphatase 3, catalytic subunit, alpha isoform
chr2_+_120307390 0.12 ENSMUST00000110716.9
ENSMUST00000028748.14
ENSMUST00000090028.13
ENSMUST00000110719.4
calpain 3
chr10_-_9776823 0.12 ENSMUST00000141722.8
syntaxin binding protein 5 (tomosyn)
chr3_+_136376440 0.11 ENSMUST00000056758.9
protein phosphatase 3, catalytic subunit, alpha isoform
chr18_+_46730765 0.11 ENSMUST00000238168.2
ENSMUST00000078079.11
ENSMUST00000168382.2
ENSMUST00000235849.2
ENSMUST00000235973.2
ENSMUST00000235455.2
ENSMUST00000237478.2
eukaryotic translation initiation factor 1A
chr9_-_100368841 0.11 ENSMUST00000098458.4
interleukin 20 receptor beta
chr9_-_109930078 0.11 ENSMUST00000196455.2
ENSMUST00000062368.13
DEAH (Asp-Glu-Ala-His) box polypeptide 30
chr9_-_108444561 0.11 ENSMUST00000074208.6
NADH:ubiquinone oxidoreductase complex assembly factor 3
chr4_-_156339769 0.11 ENSMUST00000217934.2
sterile alpha motif domain containing 11
chr17_+_35188888 0.11 ENSMUST00000173680.2
predicted gene 20481
chr11_-_107228382 0.11 ENSMUST00000040380.13
phosphatidylinositol transfer protein, cytoplasmic 1
chr17_+_28259749 0.10 ENSMUST00000233869.2
ankyrin repeat and SAM domain containing 1
chr2_-_121287174 0.10 ENSMUST00000110613.9
ENSMUST00000056312.10
serine incorporator 4
chr9_+_75213570 0.10 ENSMUST00000213990.2
guanine nucleotide binding protein (G protein), beta 5
chr1_-_165762469 0.10 ENSMUST00000069609.12
ENSMUST00000111427.9
ENSMUST00000111426.11
POU domain, class 2, transcription factor 1
chr3_+_88523730 0.10 ENSMUST00000175779.8
rho/rac guanine nucleotide exchange factor (GEF) 2
chr4_-_42661893 0.10 ENSMUST00000108006.4
interleukin 11 receptor, alpha chain 2
chr5_+_3393893 0.09 ENSMUST00000165117.8
ENSMUST00000197385.2
cyclin-dependent kinase 6
chrX_-_135858748 0.09 ENSMUST00000069803.5
thymosin beta 15b2
chr19_-_32689687 0.09 ENSMUST00000237752.2
ENSMUST00000235412.2
ATPase family, AAA domain containing 1
chr3_+_105881027 0.09 ENSMUST00000000573.9
oviductal glycoprotein 1
chr5_+_130215996 0.08 ENSMUST00000119027.8
ENSMUST00000026390.8
RAB guanine nucleotide exchange factor (GEF) 1
chr11_+_23206565 0.08 ENSMUST00000136235.2
exportin 1
chr12_+_8971603 0.08 ENSMUST00000020909.4
lysosomal-associated protein transmembrane 4A
chr3_+_94217396 0.08 ENSMUST00000049822.10
thioesterase superfamily member 4
chr4_+_116565898 0.08 ENSMUST00000135499.8
coiled-coil domain containing 163
chr19_+_36061096 0.08 ENSMUST00000025714.9
ribonuclease P/MRP 30 subunit
chr11_+_19874354 0.08 ENSMUST00000093299.13
sprouty-related EVH1 domain containing 2
chr11_+_116547932 0.07 ENSMUST00000116318.3
photoreceptor disc component
chr4_-_109333866 0.07 ENSMUST00000030284.10
ring finger protein 11
chr12_+_79255678 0.07 ENSMUST00000021548.12
retinol dehydrogenase 12
chr14_-_64654397 0.07 ENSMUST00000210428.2
methionine sulfoxide reductase A
chr19_-_12742811 0.07 ENSMUST00000112933.2
ciliary neurotrophic factor
chr14_-_121976273 0.07 ENSMUST00000212376.3
ENSMUST00000239077.2
dedicator of cytokinesis 9
chr5_-_92583078 0.07 ENSMUST00000038514.15
nucleoporin 54
chr5_-_137785903 0.07 ENSMUST00000196022.2
methylphosphate capping enzyme
chr10_+_21869776 0.07 ENSMUST00000092673.11
serum/glucocorticoid regulated kinase 1
chr10_+_18283405 0.07 ENSMUST00000037341.14
NHS-like 1
chr2_+_101455079 0.07 ENSMUST00000111227.2
recombination activating gene 2
chr7_+_24206431 0.06 ENSMUST00000176880.2
zinc finger protein 428
chr10_-_6930376 0.06 ENSMUST00000105617.8
interaction protein for cytohesin exchange factors 1
chr11_+_69886652 0.06 ENSMUST00000101526.9
PHD finger protein 23
chr7_+_5065142 0.06 ENSMUST00000005041.15
ENSMUST00000209099.2
U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2
chr5_-_134485081 0.06 ENSMUST00000111244.5
general transcription factor II I repeat domain-containing 1
chr8_+_79235946 0.06 ENSMUST00000209490.2
ENSMUST00000034111.10
solute carrier family 10 (sodium/bile acid cotransporter family), member 7
chr14_-_20027112 0.06 ENSMUST00000159028.8
guanine nucleotide binding protein (G protein), gamma 2
chr5_-_144160397 0.06 ENSMUST00000085701.7
tectonin beta-propeller repeat containing 1
chrX_-_42256694 0.06 ENSMUST00000115058.8
ENSMUST00000115059.8
teneurin transmembrane protein 1
chr2_-_145776934 0.06 ENSMUST00000001818.5
crooked neck pre-mRNA splicing factor 1
chr7_-_4517608 0.06 ENSMUST00000166959.8
troponin T1, skeletal, slow
chr17_+_34092811 0.06 ENSMUST00000226885.2
small integral membrane protein 40, pseudogene
chrX_+_92718695 0.05 ENSMUST00000045898.4
phosphate cytidylyltransferase 1, choline, beta isoform
chr11_-_97242842 0.05 ENSMUST00000093942.5
G protein-coupled receptor 179
chr10_-_125164399 0.05 ENSMUST00000063318.10
solute carrier family 16 (monocarboxylic acid transporters), member 7
chr2_+_69500444 0.05 ENSMUST00000100050.4
kelch-like 41
chr13_+_94925382 0.05 ENSMUST00000046644.7
tubulin cofactor A
chr19_+_8861096 0.05 ENSMUST00000187504.7
LBH domain containing 1
chr17_+_57077258 0.05 ENSMUST00000168666.3
proline rich 22
chr9_+_35334878 0.05 ENSMUST00000154652.8
cell adhesion molecule-related/down-regulated by oncogenes
chr1_-_4430481 0.05 ENSMUST00000027032.6
retinitis pigmentosa 1 (human)
chrX_+_55825033 0.04 ENSMUST00000114772.9
ENSMUST00000114768.10
ENSMUST00000155882.8
four and a half LIM domains 1
chr12_+_79255702 0.04 ENSMUST00000122227.8
retinol dehydrogenase 12
chr11_-_99383938 0.04 ENSMUST00000006969.8
keratin 23
chr8_+_12965876 0.04 ENSMUST00000110876.9
ENSMUST00000110879.9
mcf.2 transforming sequence-like
chr19_-_6127211 0.04 ENSMUST00000160590.2
ENSMUST00000025711.13
VPS51 GARP complex subunit
chr2_+_89642395 0.04 ENSMUST00000214508.2
olfactory receptor 1255
chr9_+_50528608 0.04 ENSMUST00000000171.15
ENSMUST00000151197.8
PIH1 domain containing 2
chr8_-_106863521 0.04 ENSMUST00000115979.9
epithelial splicing regulatory protein 2
chr3_-_9029097 0.04 ENSMUST00000091354.12
ENSMUST00000094381.11
tumor protein D52
chr2_+_124910037 0.04 ENSMUST00000070353.4
solute carrier family 24, member 5
chr10_+_25284244 0.04 ENSMUST00000092645.7
ENSMUST00000219805.2
erythrocyte membrane protein band 4.1 like 2
chr14_+_59438879 0.04 ENSMUST00000140136.9
ENSMUST00000142326.2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
chr11_+_97917520 0.04 ENSMUST00000092425.11
ribosomal protein L19
chr3_+_88523440 0.04 ENSMUST00000177498.8
ENSMUST00000176500.8
rho/rac guanine nucleotide exchange factor (GEF) 2
chr5_-_90487583 0.04 ENSMUST00000197021.2
ankyrin repeat domain 17
chr7_-_4517559 0.04 ENSMUST00000163538.8
troponin T1, skeletal, slow
chr11_-_29197222 0.04 ENSMUST00000020754.10
cilia and flagella associated protein 36
chr2_-_101459274 0.04 ENSMUST00000099682.9
intraflagellar transport associated protein
chrX_-_99670174 0.04 ENSMUST00000015812.12
PDZ domain containing 11
chr9_+_35332837 0.04 ENSMUST00000119129.10
cell adhesion molecule-related/down-regulated by oncogenes
chr1_+_9615619 0.04 ENSMUST00000072079.9
ribosome biogenesis regulator 1
chr12_-_114579763 0.03 ENSMUST00000103500.2
immunoglobulin heavy variable V1-12
chr12_-_102406069 0.03 ENSMUST00000021607.9
legumain
chr1_+_12762501 0.03 ENSMUST00000177608.8
ENSMUST00000180062.8
sulfatase 1
chrX_+_133486391 0.03 ENSMUST00000113211.8
ribosomal protein L36A
chr7_-_132616977 0.03 ENSMUST00000169570.8
C-terminal binding protein 2
chr9_+_108367801 0.03 ENSMUST00000006854.13
ubiquitin specific peptidase 19
chr15_-_101801351 0.03 ENSMUST00000100179.2
keratin 76
chrX_+_7473338 0.03 ENSMUST00000115726.9
ENSMUST00000133637.8
ENSMUST00000115725.9
calcium channel, voltage-dependent, alpha 1F subunit
chr1_-_84818223 0.03 ENSMUST00000186465.7
thyroid hormone receptor interactor 12
chr10_-_80257681 0.03 ENSMUST00000156244.2
transcription factor 3
chr11_+_4587733 0.03 ENSMUST00000070257.14
ENSMUST00000109930.3
activating signal cointegrator 1 complex subunit 2
chr6_-_93890520 0.03 ENSMUST00000203688.3
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr17_-_59298338 0.02 ENSMUST00000025064.14
PDZ and pleckstrin homology domains 1
chr12_-_118265103 0.02 ENSMUST00000222314.2
ENSMUST00000026367.11
trans-acting transcription factor 4
chr16_+_32066037 0.02 ENSMUST00000141820.8
ENSMUST00000178573.8
ENSMUST00000023474.4
ENSMUST00000135289.2
WD repeat domain 53
chr15_+_91722524 0.02 ENSMUST00000109276.8
ENSMUST00000088555.10
ENSMUST00000100293.9
ENSMUST00000126508.8
ENSMUST00000239545.1
submandibular gland protein C
mucin 19
chr2_+_22958179 0.02 ENSMUST00000227663.2
ENSMUST00000028121.15
ENSMUST00000227809.2
ENSMUST00000144088.2
acyl-Coenzyme A binding domain containing 5
chr4_+_19280850 0.02 ENSMUST00000102999.2
cyclic nucleotide gated channel beta 3
chrX_+_162923474 0.02 ENSMUST00000073973.11
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
chr4_+_80752360 0.02 ENSMUST00000133655.8
ENSMUST00000006151.13
tyrosinase-related protein 1
chr17_-_57307018 0.02 ENSMUST00000002740.3
persephin
chr9_-_71070506 0.02 ENSMUST00000074465.9
aquaporin 9
chr4_-_140780972 0.02 ENSMUST00000040222.14
ciliary rootlet coiled-coil, rootletin
chrX_+_55824797 0.02 ENSMUST00000114773.10
four and a half LIM domains 1
chr5_-_87240405 0.02 ENSMUST00000132667.2
ENSMUST00000145617.8
ENSMUST00000094649.11
UDP glucuronosyltransferase 2 family, polypeptide B36
chr2_+_119156265 0.02 ENSMUST00000102517.4
delta like canonical Notch ligand 4
chr10_-_129023288 0.02 ENSMUST00000072976.4
olfactory receptor 773
chr5_-_86780277 0.02 ENSMUST00000116553.9
transmembrane protease, serine 11f
chr10_-_18890281 0.02 ENSMUST00000146388.2
tumor necrosis factor, alpha-induced protein 3
chr1_+_12762712 0.02 ENSMUST00000186051.7
sulfatase 1
chr19_-_32173824 0.02 ENSMUST00000151822.2
sphingomyelin synthase 1
chr4_+_80752535 0.02 ENSMUST00000102831.8
tyrosinase-related protein 1
chr3_-_144555062 0.01 ENSMUST00000159989.2
chloride channel accessory 3B
chr7_+_126575510 0.01 ENSMUST00000206780.2
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)
chr5_+_88523967 0.01 ENSMUST00000073363.2
amelotin
chr7_+_88079534 0.01 ENSMUST00000208478.2
RAB38, member RAS oncogene family
chr2_+_136734088 0.01 ENSMUST00000099311.9
SLX4 interacting protein
chr10_+_90412827 0.01 ENSMUST00000182550.8
ENSMUST00000099364.12
ankyrin repeat and sterile alpha motif domain containing 1B
chr11_+_67167950 0.01 ENSMUST00000019625.12
myosin, heavy polypeptide 8, skeletal muscle, perinatal
chr14_-_8457069 0.01 ENSMUST00000022257.4
ataxin 7
chr14_-_49482846 0.01 ENSMUST00000227113.2
ENSMUST00000130853.2
ENSMUST00000228936.2
ENSMUST00000022398.15
coiled-coil domain containing 198
chr9_+_32135540 0.01 ENSMUST00000168954.9
Rho GTPase activating protein 32
chr2_-_113047397 0.01 ENSMUST00000080673.13
ENSMUST00000208151.2
ENSMUST00000208290.2
ryanodine receptor 3
chr1_+_44022321 0.01 ENSMUST00000190207.2
tripeptidyl peptidase II
chr3_+_121838076 0.01 ENSMUST00000013995.13
ATP-binding cassette, sub-family A (ABC1), member 4
chr2_+_85615818 0.01 ENSMUST00000047870.6
olfactory receptor 1015
chr11_+_69886603 0.01 ENSMUST00000018716.10
PHD finger protein 23
chr11_+_94901104 0.01 ENSMUST00000124735.2
sterile alpha motif domain containing 14
chr4_+_101407608 0.01 ENSMUST00000094953.11
ENSMUST00000106933.2
DnaJ heat shock protein family (Hsp40) member C6
chr13_-_105431153 0.01 ENSMUST00000224749.2
ring finger protein 180
chr15_+_91722458 0.01 ENSMUST00000109277.8
submandibular gland protein C
chr16_-_26786995 0.01 ENSMUST00000231969.2
geminin coiled-coil domain containing
chr13_-_105430932 0.01 ENSMUST00000224662.2
ring finger protein 180
chr9_+_38240356 0.01 ENSMUST00000214155.2
ENSMUST00000212354.3
olfactory receptor 25

Network of associatons between targets according to the STRING database.

First level regulatory network of Pitx1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0015825 L-serine transport(GO:0015825)
0.1 0.3 GO:0006532 fumarate metabolic process(GO:0006106) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533)
0.1 0.2 GO:0010615 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.1 0.2 GO:1902071 regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.1 0.6 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.3 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.1 0.2 GO:0046710 GDP metabolic process(GO:0046710)
0.1 0.2 GO:1902226 regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972)
0.0 0.2 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.1 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.2 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.0 0.6 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.1 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.0 0.2 GO:1904349 positive regulation of small intestine smooth muscle contraction(GO:1904349)
0.0 0.7 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.6 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.2 GO:0006363 termination of RNA polymerase I transcription(GO:0006363) diacylglycerol catabolic process(GO:0046340)
0.0 0.3 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.3 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.1 GO:0001807 regulation of type IV hypersensitivity(GO:0001807)
0.0 0.2 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.0 0.4 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.3 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.0 0.3 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.2 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.5 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.2 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.1 GO:0036275 response to 5-fluorouracil(GO:0036275)
0.0 0.2 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.1 GO:1990091 sodium-dependent self proteolysis(GO:1990091)
0.0 0.4 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.2 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.2 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.2 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.2 GO:0032056 positive regulation of translation in response to stress(GO:0032056)
0.0 0.1 GO:0048691 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.1 GO:0071698 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.1 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.0 0.2 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.0 GO:0006583 melanin biosynthetic process from tyrosine(GO:0006583)
0.0 0.1 GO:0036215 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.0 0.2 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.1 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.3 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.0 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0097132 cyclin D2-CDK6 complex(GO:0097132)
0.0 0.4 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.1 GO:0030312 external encapsulating structure(GO:0030312)
0.0 0.2 GO:0005827 polar microtubule(GO:0005827)
0.0 0.6 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.2 GO:0044754 autolysosome(GO:0044754)
0.0 0.2 GO:0005861 troponin complex(GO:0005861)
0.0 0.7 GO:0045171 intercellular bridge(GO:0045171)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0032093 SAM domain binding(GO:0032093)
0.1 0.3 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.1 0.6 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.1 0.2 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 0.2 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.2 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.6 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.2 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.5 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.3 GO:0004568 chitinase activity(GO:0004568)
0.0 0.1 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.1 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.1 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.0 0.2 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.3 GO:0015288 porin activity(GO:0015288)
0.0 0.4 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.2 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.0 0.2 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.3 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.2 GO:0031014 troponin T binding(GO:0031014)
0.0 0.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.5 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.4 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 1.1 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.2 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.7 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)