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avrg: GFI1 WT vs 36n/n vs KD

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Results for Pitx2_Otx2

Z-value: 2.98

Motif logo

Transcription factors associated with Pitx2_Otx2

Gene Symbol Gene ID Gene Info
ENSMUSG00000028023.17 paired-like homeodomain transcription factor 2
ENSMUSG00000021848.17 orthodenticle homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pitx2mm39_v1_chr3_+_129007599_1290076210.922.8e-02Click!
Otx2mm39_v1_chr14_-_48904958_48904994-0.395.2e-01Click!

Activity profile of Pitx2_Otx2 motif

Sorted Z-values of Pitx2_Otx2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_40586029 3.85 ENSMUST00000101347.10
methionine adenosyltransferase II, beta
chr11_+_101339233 3.14 ENSMUST00000010502.13
interferon-induced protein 35
chr10_+_128736827 2.47 ENSMUST00000219317.2
CD63 antigen
chr19_-_41884599 2.12 ENSMUST00000038677.5
ribosomal RNA processing 12 homolog
chr11_-_106889291 2.06 ENSMUST00000124541.8
karyopherin (importin) alpha 2
chr17_+_35643818 2.05 ENSMUST00000174699.8
histocompatibility 2, Q region locus 6
chr15_+_59186876 2.05 ENSMUST00000022977.14
ENSMUST00000100640.5
squalene epoxidase
chr11_-_115918784 1.94 ENSMUST00000106454.8
H3.3 histone B
chr12_-_75678092 1.94 ENSMUST00000238938.2
ribosomal protein, large P2, pseudogene 1
chr17_+_35643853 1.87 ENSMUST00000113879.4
histocompatibility 2, Q region locus 6
chr4_+_102617332 1.87 ENSMUST00000066824.14
SH3-domain GRB2-like (endophilin) interacting protein 1
chr11_+_96920751 1.85 ENSMUST00000021249.11
secernin 2
chr3_-_153618603 1.84 ENSMUST00000089950.11
Rab geranylgeranyl transferase, b subunit
chr8_+_123789681 1.83 ENSMUST00000142541.8
ENSMUST00000125975.8
SPG7, paraplegin matrix AAA peptidase subunit
chr11_-_59727752 1.67 ENSMUST00000156837.2
COP9 signalosome subunit 3
chr5_-_65585720 1.62 ENSMUST00000131263.3
UDP-glucose dehydrogenase
chr11_-_93856783 1.62 ENSMUST00000021220.10
NME/NM23 nucleoside diphosphate kinase 1
chr2_-_126342551 1.57 ENSMUST00000129187.2
ATPase, class I, type 8B, member 4
chr1_-_153425791 1.54 ENSMUST00000041874.9
N-acetylneuraminate pyruvate lyase
chr19_+_8870362 1.49 ENSMUST00000096249.7
integrator complex subunit 5
chr15_+_80832685 1.46 ENSMUST00000023043.10
ENSMUST00000164806.6
ENSMUST00000207170.2
ENSMUST00000168756.8
adenylosuccinate lyase
chr8_-_111758343 1.46 ENSMUST00000065784.6
DEAD box helicase 19b
chr14_+_52348396 1.39 ENSMUST00000111600.11
retinitis pigmentosa GTPase regulator interacting protein 1
chr8_-_117720198 1.36 ENSMUST00000040484.6
glycine cleavage system protein H (aminomethyl carrier)
chr11_+_88861073 1.34 ENSMUST00000107898.8
coilin
chr14_+_31888061 1.33 ENSMUST00000164341.2
nuclear receptor coactivator 4
chr2_+_91376650 1.32 ENSMUST00000099716.11
ENSMUST00000046769.16
ENSMUST00000111337.3
cytoskeleton associated protein 5
chr17_+_35658131 1.29 ENSMUST00000071951.14
ENSMUST00000116598.10
ENSMUST00000078205.14
ENSMUST00000076256.8
histocompatibility 2, Q region locus 7
chr10_+_7543260 1.26 ENSMUST00000040135.9
nucleoporin 43
chr11_-_120687195 1.24 ENSMUST00000143139.8
ENSMUST00000129955.2
ENSMUST00000026151.11
ENSMUST00000167023.8
ENSMUST00000106133.8
ENSMUST00000106135.8
dihydrouridine synthase 1-like (S. cerevisiae)
chr11_+_101333115 1.23 ENSMUST00000077856.13
ribosomal protein L27
chr17_-_6923299 1.22 ENSMUST00000179554.3
dynein light chain Tctex-type 1F
chr5_-_134485430 1.21 ENSMUST00000200944.4
ENSMUST00000202280.4
ENSMUST00000074114.12
ENSMUST00000100654.10
ENSMUST00000100650.10
ENSMUST00000111245.9
ENSMUST00000202554.4
ENSMUST00000073161.12
ENSMUST00000100652.10
ENSMUST00000171794.9
ENSMUST00000167084.9
general transcription factor II I repeat domain-containing 1
chr12_+_83572774 1.19 ENSMUST00000223291.2
DDB1 and CUL4 associated factor 4
chr19_+_6111204 1.19 ENSMUST00000162726.5
zinc finger, HIT domain containing 2
chrX_+_52076998 1.17 ENSMUST00000026723.9
hypoxanthine guanine phosphoribosyl transferase
chr8_+_85786684 1.17 ENSMUST00000095220.4
F-box and WD-40 domain protein 9
chr17_-_66175046 1.16 ENSMUST00000233399.2
ralA binding protein 1
chr8_-_110335255 1.15 ENSMUST00000123605.9
ENSMUST00000143900.8
ENSMUST00000128350.3
dihydroorotate dehydrogenase
chrM_+_8603 1.14 ENSMUST00000082409.1
mitochondrially encoded cytochrome c oxidase III
chr5_+_139239247 1.14 ENSMUST00000138508.8
ENSMUST00000110878.2
golgi to ER traffic protein 4
chr2_-_112089627 1.12 ENSMUST00000043970.2
NUT midline carcinoma, family member 1
chr6_-_88875646 1.11 ENSMUST00000058011.8
minichromosome maintenance complex component 2
chr5_-_100720063 1.11 ENSMUST00000031264.12
placenta-specific 8
chrM_+_7758 1.09 ENSMUST00000082407.1
mitochondrially encoded ATP synthase 8
chr4_-_116508842 1.09 ENSMUST00000030455.15
aldo-keto reductase family 1, member A1 (aldehyde reductase)
chr6_+_58810674 1.09 ENSMUST00000041401.11
hect domain and RLD 3
chr11_-_48717482 1.08 ENSMUST00000104959.2
predicted gene 12184
chr4_-_44066960 1.08 ENSMUST00000173234.8
ENSMUST00000173274.2
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr5_+_145020640 1.08 ENSMUST00000031625.15
actin related protein 2/3 complex, subunit 1A
chr8_-_23680954 1.07 ENSMUST00000209507.2
glycerol-3-phosphate acyltransferase 4
chr14_+_55129950 1.06 ENSMUST00000140691.8
poly(A) binding protein, nuclear 1
chr1_+_87998487 1.04 ENSMUST00000073772.5
UDP glucuronosyltransferase 1 family, polypeptide A9
chr2_+_126922156 1.03 ENSMUST00000142737.3
biliverdin reductase A
chr2_+_61542038 1.02 ENSMUST00000028278.14
proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
chr14_+_74973081 1.02 ENSMUST00000177283.8
esterase D/formylglutathione hydrolase
chr2_-_25101354 1.00 ENSMUST00000059849.15
negative elongation factor complex member B
chr5_+_110478558 1.00 ENSMUST00000112481.2
polymerase (DNA directed), epsilon
chr15_+_81872036 0.99 ENSMUST00000165777.8
X-ray repair complementing defective repair in Chinese hamster cells 6
chr5_-_21260878 0.99 ENSMUST00000030556.8
protein tyrosine phosphatase, non-receptor type 12
chr4_+_89055359 0.99 ENSMUST00000058030.10
methylthioadenosine phosphorylase
chr7_-_45116197 0.98 ENSMUST00000211195.2
ENSMUST00000210019.2
BCL2-associated X protein
chr7_+_16515265 0.98 ENSMUST00000108496.9
solute carrier family 1 (neutral amino acid transporter), member 5
chr10_-_62178453 0.98 ENSMUST00000143179.2
ENSMUST00000130422.8
hexokinase 1
chr6_+_115521625 0.97 ENSMUST00000130425.8
ENSMUST00000040234.9
tRNA splicing endonuclease subunit 2
chr6_-_115739284 0.97 ENSMUST00000166254.7
ENSMUST00000170625.8
transmembrane protein 40
chr15_+_6451721 0.96 ENSMUST00000163082.2
disabled 2, mitogen-responsive phosphoprotein
chr14_+_66043515 0.96 ENSMUST00000139644.2
PDZ binding kinase
chr10_-_40178182 0.95 ENSMUST00000099945.6
ENSMUST00000238953.2
ENSMUST00000238969.2
S-adenosylmethionine decarboxylase 1
chr6_+_90527762 0.95 ENSMUST00000130418.8
ENSMUST00000032175.11
ENSMUST00000203111.2
aldehyde dehydrogenase 1 family, member L1
chr19_-_32717166 0.94 ENSMUST00000235142.2
ENSMUST00000070210.6
ENSMUST00000236011.2
ATPase family, AAA domain containing 1
chr17_+_6697511 0.93 ENSMUST00000179569.3
dynein light chain Tctex-type 1B
chr10_-_127147609 0.93 ENSMUST00000037290.12
ENSMUST00000171564.8
methionine-tRNA synthetase 1
chr5_+_38417710 0.93 ENSMUST00000119047.8
transmembrane protein 128
chr7_+_101875019 0.93 ENSMUST00000142873.8
post-GPI attachment to proteins 2
chr10_+_12881087 0.93 ENSMUST00000105139.5
splicing factor 3b, subunit 5
chr7_+_46490899 0.93 ENSMUST00000147535.8
lactate dehydrogenase A
chr2_+_144435974 0.92 ENSMUST00000136628.2
small integral membrane protein 26
chr11_+_60345412 0.92 ENSMUST00000018568.4
developmentally regulated GTP binding protein 2
chr10_+_80128248 0.92 ENSMUST00000068408.14
ENSMUST00000062674.7
ribosomal protein S15
chr14_+_43951187 0.92 ENSMUST00000094051.6
predicted gene 7324
chr2_-_93652882 0.91 ENSMUST00000111248.8
ENSMUST00000184931.8
ENSMUST00000145838.8
ENSMUST00000028623.13
exostosin glycosyltransferase 2
chr18_+_34869412 0.91 ENSMUST00000105038.3
predicted gene 3550
chr7_-_24997291 0.91 ENSMUST00000148150.8
ENSMUST00000155118.2
platelet-activating factor acetylhydrolase, isoform 1b, subunit 3
chr9_-_100368841 0.90 ENSMUST00000098458.4
interleukin 20 receptor beta
chr3_+_41510160 0.90 ENSMUST00000026865.15
ENSMUST00000194181.6
ENSMUST00000195846.6
jade family PHD finger 1
chr6_+_140568366 0.90 ENSMUST00000032359.15
AE binding protein 2
chr7_-_19307718 0.90 ENSMUST00000117222.2
gem nuclear organelle associated protein 7
chr6_-_131270136 0.89 ENSMUST00000032307.12
mago homolog B, exon junction complex core component
chr10_+_128744689 0.88 ENSMUST00000105229.9
CD63 antigen
chr17_+_48539782 0.88 ENSMUST00000113251.10
ENSMUST00000048782.7
triggering receptor expressed on myeloid cells 1
chr11_-_116164928 0.88 ENSMUST00000106425.4
signal recognition particle 68
chr7_-_45116216 0.88 ENSMUST00000210392.2
ENSMUST00000211365.2
BCL2-associated X protein
chr18_+_80249980 0.86 ENSMUST00000156400.9
predicted gene 16286
chr9_+_110248815 0.86 ENSMUST00000035061.9
neutrophilic granule protein
chr19_-_32717138 0.85 ENSMUST00000236985.2
ATPase family, AAA domain containing 1
chr9_-_107863062 0.85 ENSMUST00000048568.6
inka box actin regulator 1
chr15_+_76585644 0.85 ENSMUST00000019224.9
major facilitator superfamily domain containing 3
chrX_+_133657312 0.85 ENSMUST00000081834.10
ENSMUST00000086880.11
ENSMUST00000086884.5
armadillo repeat containing, X-linked 3
chr8_-_11685726 0.85 ENSMUST00000033905.13
ENSMUST00000169782.3
ankyrin repeat domain 10
chr7_-_113853894 0.84 ENSMUST00000033012.9
coatomer protein complex, subunit beta 1
chr8_-_70959360 0.84 ENSMUST00000136913.2
ENSMUST00000075175.12
required for excision 1-B domain containing
chr7_-_121700958 0.84 ENSMUST00000139456.2
ENSMUST00000106471.9
ENSMUST00000123296.8
ENSMUST00000033157.10
NADH:ubiquinone oxidoreductase subunit AB1
chrM_+_7779 0.83 ENSMUST00000082408.1
mitochondrially encoded ATP synthase 6
chr2_+_32647246 0.83 ENSMUST00000009707.14
ENSMUST00000177382.2
ENSMUST00000140999.2
torsin family 2, member A
chr9_-_21838584 0.83 ENSMUST00000213698.2
transmembrane protein 205
chr3_+_95226093 0.83 ENSMUST00000139866.2
ceramide synthase 2
chr8_+_70583971 0.83 ENSMUST00000211898.2
ENSMUST00000095273.7
nuclear receptor 2C2-associated protein
chr7_-_126391657 0.82 ENSMUST00000032936.8
protein phosphatase 4, catalytic subunit
chr11_+_32155415 0.82 ENSMUST00000039601.10
ENSMUST00000149043.3
small nuclear ribonucleoprotein 25 (U11/U12)
chr16_+_4559426 0.82 ENSMUST00000120232.8
heme oxygenase 2
chr11_-_60702081 0.81 ENSMUST00000018744.15
serine hydroxymethyltransferase 1 (soluble)
chr19_+_10183397 0.81 ENSMUST00000166412.2
transmembrane protein 258
chr6_-_124791259 0.81 ENSMUST00000172132.10
ENSMUST00000239432.2
triosephosphate isomerase 1
chr17_+_28532487 0.80 ENSMUST00000114803.9
ENSMUST00000114801.9
ENSMUST00000114804.11
Fanconi anemia, complementation group E
chr4_-_149222057 0.80 ENSMUST00000030813.10
centromere protein S
chr7_+_120234399 0.79 ENSMUST00000033176.7
ENSMUST00000208400.2
ubiquinol cytochrome c reductase core protein 2
chr7_-_117715351 0.79 ENSMUST00000128482.8
ENSMUST00000131840.3
ribosomal protein S15A
chr10_+_19497740 0.79 ENSMUST00000036564.8
interleukin 22 receptor, alpha 2
chr10_+_128073900 0.78 ENSMUST00000105245.3
timeless circadian clock 1
chr6_-_120799641 0.78 ENSMUST00000205049.3
ATPase, H+ transporting, lysosomal V1 subunit E1
chr19_+_44994094 0.78 ENSMUST00000236685.2
twinkle mtDNA helicase
chr19_+_8861096 0.78 ENSMUST00000187504.7
LBH domain containing 1
chr2_-_151586063 0.77 ENSMUST00000109869.2
proteasome (prosome, macropain) inhibitor subunit 1
chr15_-_99268311 0.77 ENSMUST00000081224.14
ENSMUST00000120633.2
ENSMUST00000088233.13
formin-like 3
chr13_-_113237505 0.77 ENSMUST00000224282.2
ENSMUST00000023897.7
granzyme A
chr8_+_85583611 0.76 ENSMUST00000003906.13
ENSMUST00000109754.2
phenylalanyl-tRNA synthetase, alpha subunit
chr8_+_34143266 0.76 ENSMUST00000033992.9
glutathione reductase
chr14_-_30740946 0.75 ENSMUST00000228341.2
guanine nucleotide binding protein-like 3 (nucleolar)
chr3_+_88483183 0.75 ENSMUST00000192688.6
ENSMUST00000193069.2
ENSMUST00000194604.2
signal sequence receptor, beta
chr9_-_78396407 0.75 ENSMUST00000154207.8
eukaryotic translation elongation factor 1 alpha 1
chr4_+_102617495 0.75 ENSMUST00000072481.12
ENSMUST00000156596.8
ENSMUST00000080728.13
ENSMUST00000106882.9
SH3-domain GRB2-like (endophilin) interacting protein 1
chr9_+_122942280 0.75 ENSMUST00000026891.5
ENSMUST00000215377.2
exosome component 7
chr17_+_80531870 0.74 ENSMUST00000069486.13
gem nuclear organelle associated protein 6
chr11_-_117673008 0.74 ENSMUST00000152304.3
transmembrane channel-like gene family 6
chr4_-_150994083 0.74 ENSMUST00000105674.8
ENSMUST00000105673.8
Parkinson disease (autosomal recessive, early onset) 7
chr15_+_84926909 0.74 ENSMUST00000229203.2
family with sequence similarity 118, member A
chrX_-_163033364 0.74 ENSMUST00000112263.2
BMX non-receptor tyrosine kinase
chr5_-_93354287 0.73 ENSMUST00000144514.3
cyclin I
chr9_+_103182352 0.73 ENSMUST00000035164.10
topoisomerase (DNA) II binding protein 1
chr7_-_125976580 0.72 ENSMUST00000119846.8
ENSMUST00000119754.8
ENSMUST00000032994.15
spinster homolog 1
chr11_-_69572896 0.72 ENSMUST00000066760.8
SUMO/sentrin specific peptidase 3
chr14_-_45626237 0.72 ENSMUST00000227865.2
ENSMUST00000226856.2
ENSMUST00000226276.2
ENSMUST00000046191.9
glucosamine-phosphate N-acetyltransferase 1
chr19_-_8763771 0.72 ENSMUST00000176496.8
TATA-box binding protein associated factor 6 like
chr2_+_128942900 0.71 ENSMUST00000103205.11
polymerase (RNA) I polypeptide B
chr15_+_76763501 0.70 ENSMUST00000230106.2
ENSMUST00000229831.2
ENSMUST00000229990.2
ENSMUST00000230214.2
zinc finger protein 7
predicted gene, 49527
chr10_+_79650496 0.70 ENSMUST00000218857.2
ENSMUST00000220365.2
paralemmin
chr6_+_35154319 0.70 ENSMUST00000201374.4
ENSMUST00000043815.16
nucleoporin 205
chrX_+_36138004 0.70 ENSMUST00000201117.4
ubiquitin-conjugating enzyme E2A
chr5_-_110928436 0.70 ENSMUST00000149208.2
ENSMUST00000031483.15
ENSMUST00000086643.12
ENSMUST00000170468.8
ENSMUST00000031481.13
pseudouridine synthase 1
chr6_+_55014973 0.69 ENSMUST00000003572.10
glycyl-tRNA synthetase
chr11_+_51152546 0.69 ENSMUST00000130641.8
CDC like kinase 4
chr14_-_99231754 0.69 ENSMUST00000081987.5
ribosomal protein L36A, pseudogene 1
chr2_+_90884349 0.68 ENSMUST00000067663.14
ENSMUST00000002171.14
ENSMUST00000111441.10
proteasome (prosome, macropain) 26S subunit, ATPase 3
chr18_+_38551960 0.68 ENSMUST00000236085.2
Nedd4 family interacting protein 1
chr15_-_83006957 0.68 ENSMUST00000018184.10
ribosomal RNA processing 7 homolog A
chr2_+_128942919 0.68 ENSMUST00000028874.8
polymerase (RNA) I polypeptide B
chr16_+_20470402 0.68 ENSMUST00000007212.9
ENSMUST00000232629.2
proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
chr18_+_80250007 0.67 ENSMUST00000145963.9
ENSMUST00000025464.8
ENSMUST00000125127.8
ENSMUST00000025463.14
thioredoxin-like 4A
predicted gene 16286
chr2_+_32477069 0.67 ENSMUST00000102818.11
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chr10_+_80905869 0.67 ENSMUST00000005057.7
thimet oligopeptidase 1
chr16_+_31241085 0.67 ENSMUST00000089759.9
3-hydroxybutyrate dehydrogenase, type 1
chr13_-_64514830 0.67 ENSMUST00000222971.2
cathepsin L
chr1_-_134289670 0.66 ENSMUST00000049470.11
transmembrane protein 183A
chr18_+_44960813 0.66 ENSMUST00000037763.11
YTH domain containing 2
chr10_+_81554753 0.66 ENSMUST00000085664.6
zinc finger protein 433
chr12_+_71021395 0.66 ENSMUST00000160027.8
ENSMUST00000160864.8
proteasome subunit alpha 3
chr11_+_95925711 0.66 ENSMUST00000006217.10
ENSMUST00000107700.4
SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)
chr2_+_90884612 0.66 ENSMUST00000185715.7
proteasome (prosome, macropain) 26S subunit, ATPase 3
chr15_+_76784110 0.66 ENSMUST00000068407.6
ENSMUST00000109793.3
COMM domain containing 5
chr1_+_40554513 0.66 ENSMUST00000027237.12
interleukin 18 receptor accessory protein
chr9_-_103242096 0.66 ENSMUST00000116517.9
carnitine deficiency-associated gene expressed in ventricle 3
chr18_-_84700170 0.65 ENSMUST00000168419.3
CNDP dipeptidase 2 (metallopeptidase M20 family)
chr4_-_116851550 0.65 ENSMUST00000130273.8
uroporphyrinogen decarboxylase
chrX_+_36137948 0.65 ENSMUST00000016452.11
ENSMUST00000202991.4
ENSMUST00000201068.4
ENSMUST00000200835.4
ubiquitin-conjugating enzyme E2A
chr11_-_120508713 0.65 ENSMUST00000106188.4
ENSMUST00000026129.16
phosphate cytidylyltransferase 2, ethanolamine
chr4_-_116851571 0.65 ENSMUST00000030446.15
uroporphyrinogen decarboxylase
chr4_-_149221998 0.65 ENSMUST00000176124.8
ENSMUST00000177408.2
ENSMUST00000105695.2
centromere protein S
chr15_-_99670751 0.64 ENSMUST00000175876.8
ceramide synthase 5
chr7_+_65710086 0.64 ENSMUST00000153609.8
small nuclear ribonucleoprotein polypeptide A'
chr8_+_72994152 0.63 ENSMUST00000126885.2
adaptor-related protein complex AP-1, mu subunit 1
chr15_+_81548090 0.63 ENSMUST00000023029.15
ENSMUST00000174229.8
ENSMUST00000172748.8
L3MBTL2 polycomb repressive complex 1 subunit
chr11_-_69786324 0.63 ENSMUST00000001631.7
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr15_+_102391614 0.63 ENSMUST00000229432.2
poly(rC) binding protein 2
chr16_-_55858089 0.63 ENSMUST00000059052.9
tRNA methyltransferase 10C, mitochondrial RNase P subunit
chr4_-_123611974 0.63 ENSMUST00000137312.2
ENSMUST00000106206.8
NADH:ubiquinone oxidoreductase core subunit S5
chr4_+_156194427 0.63 ENSMUST00000072554.13
ENSMUST00000169550.8
ENSMUST00000105576.2
RIKEN cDNA 9430015G10 gene
chr6_-_86710250 0.63 ENSMUST00000001185.14
germ cell-less, spermatogenesis associated 1
chr15_-_82128888 0.63 ENSMUST00000089155.6
ENSMUST00000089157.11
centromere protein M
chr10_+_82669785 0.62 ENSMUST00000219368.3
thioredoxin reductase 1
chr10_+_75768964 0.62 ENSMUST00000219839.2
coiled-coil-helix-coiled-coil-helix domain containing 10
chr1_-_185061525 0.62 ENSMUST00000027921.11
ENSMUST00000110975.8
ENSMUST00000110974.4
isoleucine-tRNA synthetase 2, mitochondrial
chr11_+_98932586 0.61 ENSMUST00000177092.8
insulin-like growth factor binding protein 4
chr4_-_116664729 0.61 ENSMUST00000106455.8
ENSMUST00000030451.10
target of EGR1, member 1 (nuclear)
chr11_-_116165024 0.61 ENSMUST00000021133.16
signal recognition particle 68
chr9_-_7836962 0.61 ENSMUST00000190341.7
ENSMUST00000054878.6
baculoviral IAP repeat-containing 2
chr7_-_84328553 0.61 ENSMUST00000069537.3
ENSMUST00000207865.2
ENSMUST00000178385.9
ENSMUST00000208782.2
zinc finger, AN1-type domain 6
chr7_+_141055135 0.60 ENSMUST00000026585.14
tetraspanin 4
chr6_+_83092476 0.60 ENSMUST00000032114.8
mannosyl-oligosaccharide glucosidase
chr15_+_97682210 0.60 ENSMUST00000117892.2
ENSMUST00000229084.2
solute carrier family 48 (heme transporter), member 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Pitx2_Otx2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0032976 release of matrix enzymes from mitochondria(GO:0032976) B cell receptor apoptotic signaling pathway(GO:1990117)
0.6 3.9 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.6 3.4 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.5 1.4 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.4 1.3 GO:0006597 spermine biosynthetic process(GO:0006597)
0.4 1.2 GO:0046101 GMP catabolic process(GO:0046038) hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.4 1.9 GO:1902340 telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
0.4 1.1 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.4 1.5 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.3 1.4 GO:0017126 nucleologenesis(GO:0017126)
0.3 1.0 GO:0046294 formaldehyde catabolic process(GO:0046294)
0.3 1.0 GO:0006788 heme oxidation(GO:0006788)
0.3 1.0 GO:0045004 DNA replication proofreading(GO:0045004)
0.3 1.0 GO:0015825 L-serine transport(GO:0015825)
0.3 0.9 GO:0009258 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.3 0.9 GO:0042275 error-free postreplication DNA repair(GO:0042275)
0.3 0.9 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.3 1.8 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.3 1.5 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.3 0.9 GO:0001807 regulation of type IV hypersensitivity(GO:0001807)
0.3 0.9 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.3 1.4 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.3 1.1 GO:2000983 regulation of ATP citrate synthase activity(GO:2000983) negative regulation of ATP citrate synthase activity(GO:2000984)
0.3 1.4 GO:0046502 uroporphyrinogen III metabolic process(GO:0046502)
0.3 0.8 GO:0006740 NADPH regeneration(GO:0006740)
0.3 0.8 GO:0019405 alditol catabolic process(GO:0019405) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.3 1.1 GO:0002071 glandular epithelial cell maturation(GO:0002071)
0.3 1.1 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.2 1.0 GO:2000284 enzyme active site formation via L-cysteine sulfinic acid(GO:0018323) primary alcohol biosynthetic process(GO:0034309) cellular response to glyoxal(GO:0036471) glycolate biosynthetic process(GO:0046295) negative regulation of TRAIL-activated apoptotic signaling pathway(GO:1903122) regulation of pyrroline-5-carboxylate reductase activity(GO:1903167) positive regulation of pyrroline-5-carboxylate reductase activity(GO:1903168) regulation of tyrosine 3-monooxygenase activity(GO:1903176) positive regulation of tyrosine 3-monooxygenase activity(GO:1903178) L-dopa metabolic process(GO:1903184) L-dopa biosynthetic process(GO:1903185) glyoxal metabolic process(GO:1903189) regulation of L-dopa biosynthetic process(GO:1903195) positive regulation of L-dopa biosynthetic process(GO:1903197) regulation of L-dopa decarboxylase activity(GO:1903198) positive regulation of L-dopa decarboxylase activity(GO:1903200) positive regulation of cellular amino acid biosynthetic process(GO:2000284)
0.2 1.0 GO:0000390 spliceosomal complex disassembly(GO:0000390)
0.2 0.7 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.2 1.0 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.2 1.2 GO:0015965 diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966)
0.2 0.7 GO:0060160 negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.2 2.3 GO:0018344 protein geranylgeranylation(GO:0018344)
0.2 1.2 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.2 1.5 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.2 1.1 GO:0019853 L-ascorbic acid biosynthetic process(GO:0019853)
0.2 0.6 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.2 1.7 GO:0018002 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.2 0.9 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.2 1.1 GO:0006041 glucosamine metabolic process(GO:0006041)
0.2 0.8 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.2 0.6 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.2 0.6 GO:1902524 positive regulation of protein K63-linked ubiquitination(GO:1902523) positive regulation of protein K48-linked ubiquitination(GO:1902524) positive regulation of protein monoubiquitination(GO:1902527)
0.2 0.6 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.2 1.0 GO:0046149 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.2 1.2 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.2 2.1 GO:0006228 UTP biosynthetic process(GO:0006228)
0.2 0.6 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.2 0.6 GO:1902071 regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.2 0.5 GO:1901874 negative regulation of cellular respiration(GO:1901856) regulation of post-translational protein modification(GO:1901873) negative regulation of post-translational protein modification(GO:1901874)
0.2 0.5 GO:0002481 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476) antigen processing and presentation of exogenous peptide antigen via MHC class Ib(GO:0002477) antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent(GO:0002481) cytosol to ER transport(GO:0046967)
0.2 0.9 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.2 0.5 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.2 0.7 GO:1902990 mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.2 2.8 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.2 1.3 GO:0009249 protein lipoylation(GO:0009249)
0.2 0.5 GO:0090673 endothelial cell-matrix adhesion(GO:0090673)
0.2 1.3 GO:0061621 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.2 0.5 GO:0071846 actin filament debranching(GO:0071846)
0.2 0.6 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.2 1.0 GO:0035026 leading edge cell differentiation(GO:0035026)
0.2 1.6 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.2 1.9 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.2 0.6 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.2 0.8 GO:1904976 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
0.2 0.5 GO:0046462 monoacylglycerol metabolic process(GO:0046462)
0.2 0.5 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734)
0.2 0.9 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.2 0.2 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.1 0.4 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.1 1.0 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.1 1.1 GO:0036506 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.1 1.0 GO:0006166 purine ribonucleoside salvage(GO:0006166)
0.1 0.4 GO:0051030 snRNA transport(GO:0051030)
0.1 0.4 GO:0006097 glyoxylate cycle(GO:0006097)
0.1 0.4 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.1 1.5 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.1 1.5 GO:0016180 snRNA processing(GO:0016180)
0.1 0.7 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.1 1.2 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.1 0.3 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.1 0.5 GO:2000521 positive regulation of mononuclear cell migration(GO:0071677) negative regulation of immunological synapse formation(GO:2000521) regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001188) negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001189)
0.1 0.4 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.1 0.9 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 0.4 GO:0036275 response to 5-fluorouracil(GO:0036275)
0.1 1.0 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.1 0.5 GO:1900533 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.1 0.4 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.1 1.1 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.1 0.7 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 5.2 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.1 0.4 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.1 0.7 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.1 0.5 GO:0042335 cuticle development(GO:0042335)
0.1 2.5 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.1 0.3 GO:1904828 regulation of hydrogen sulfide biosynthetic process(GO:1904826) positive regulation of hydrogen sulfide biosynthetic process(GO:1904828)
0.1 2.2 GO:0000338 protein deneddylation(GO:0000338)
0.1 0.7 GO:0045829 negative regulation of isotype switching(GO:0045829) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.1 1.0 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.1 0.8 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 3.1 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 0.3 GO:0031990 mRNA export from nucleus in response to heat stress(GO:0031990)
0.1 1.1 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.1 0.5 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1 0.3 GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.1 0.5 GO:0033683 nucleotide-excision repair, DNA incision(GO:0033683)
0.1 0.3 GO:0006238 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) UMP salvage(GO:0044206) CMP metabolic process(GO:0046035)
0.1 1.6 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.1 0.3 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.1 2.0 GO:0036297 interstrand cross-link repair(GO:0036297)
0.1 0.9 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.3 GO:0046061 DNA protection(GO:0042262) dATP catabolic process(GO:0046061)
0.1 0.2 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1 0.6 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 0.3 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.1 0.5 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 0.3 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
0.1 2.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.5 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.1 0.7 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.1 0.3 GO:0030961 peptidyl-arginine hydroxylation(GO:0030961)
0.1 0.9 GO:0019661 glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.1 0.4 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.1 0.5 GO:0072737 response to diamide(GO:0072737) cellular response to diamide(GO:0072738)
0.1 0.5 GO:0034227 tRNA thio-modification(GO:0034227)
0.1 0.4 GO:0038096 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.1 1.1 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.1 0.4 GO:0000915 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.1 1.0 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.1 1.0 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1 0.6 GO:1901678 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.1 0.4 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.1 0.4 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.1 0.3 GO:0018343 protein farnesylation(GO:0018343)
0.1 0.1 GO:0050787 detoxification of mercury ion(GO:0050787)
0.1 0.3 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 1.8 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1 0.7 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 0.6 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 0.3 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.1 0.9 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291)
0.1 0.5 GO:0021539 subthalamus development(GO:0021539)
0.1 0.6 GO:0019614 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.1 1.0 GO:0050755 chemokine metabolic process(GO:0050755)
0.1 0.2 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.1 0.5 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.1 2.2 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.1 0.4 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.1 0.3 GO:0035524 proline transmembrane transport(GO:0035524)
0.1 0.4 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.1 0.5 GO:0090383 phagosome acidification(GO:0090383)
0.1 0.3 GO:0015938 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) acetyl-CoA catabolic process(GO:0046356)
0.1 0.6 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.2 GO:0015680 intracellular copper ion transport(GO:0015680)
0.1 3.0 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.1 0.5 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.1 0.6 GO:0071231 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713) cellular response to folic acid(GO:0071231)
0.1 0.3 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.1 0.3 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.1 0.4 GO:0060336 negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
0.1 1.4 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1 0.5 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 1.0 GO:0046697 decidualization(GO:0046697)
0.1 0.5 GO:2000774 positive regulation of cell aging(GO:0090343) positive regulation of cellular senescence(GO:2000774)
0.1 0.4 GO:1903772 regulation of viral budding via host ESCRT complex(GO:1903772)
0.1 1.3 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 0.6 GO:0070475 rRNA base methylation(GO:0070475)
0.1 0.2 GO:0006667 sphinganine metabolic process(GO:0006667)
0.1 0.8 GO:0016139 glycoside catabolic process(GO:0016139)
0.1 0.5 GO:0007000 nucleolus organization(GO:0007000)
0.1 0.7 GO:0071294 cellular response to zinc ion(GO:0071294)
0.1 1.5 GO:0006623 protein targeting to vacuole(GO:0006623)
0.1 1.6 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 0.3 GO:0001692 histamine metabolic process(GO:0001692)
0.1 0.6 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.1 0.5 GO:0006689 ganglioside catabolic process(GO:0006689)
0.1 0.9 GO:0006415 translational termination(GO:0006415)
0.1 0.6 GO:0043485 endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.1 0.3 GO:0090168 Golgi reassembly(GO:0090168)
0.1 0.7 GO:0001865 NK T cell differentiation(GO:0001865)
0.1 0.3 GO:1901297 positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.1 0.2 GO:0034201 response to oleic acid(GO:0034201)
0.1 0.6 GO:0060330 regulation of response to interferon-gamma(GO:0060330)
0.1 0.5 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.1 0.4 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.1 1.0 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.1 0.6 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.1 0.2 GO:0036015 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.1 0.3 GO:1990166 positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184) protein localization to site of double-strand break(GO:1990166)
0.1 0.5 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.1 0.6 GO:0046606 negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.1 2.3 GO:0008089 anterograde axonal transport(GO:0008089)
0.1 0.5 GO:0045916 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.1 GO:0090669 telomerase RNA stabilization(GO:0090669)
0.0 0.1 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.0 0.4 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0 0.2 GO:0048478 replication fork protection(GO:0048478)
0.0 0.3 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.0 0.4 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.1 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0 0.1 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.0 0.5 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.2 GO:1900060 negative regulation of ceramide biosynthetic process(GO:1900060)
0.0 0.7 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.4 GO:0042148 strand invasion(GO:0042148)
0.0 0.3 GO:1902988 regulation of neuronal signal transduction(GO:1902847) neurofibrillary tangle assembly(GO:1902988) regulation of neurofibrillary tangle assembly(GO:1902996) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0 0.2 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.5 GO:0006983 ER overload response(GO:0006983)
0.0 0.3 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.3 GO:0002317 plasma cell differentiation(GO:0002317)
0.0 0.3 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.0 0.2 GO:0015827 aromatic amino acid transport(GO:0015801) tryptophan transport(GO:0015827)
0.0 0.7 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.0 0.2 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.3 GO:1904222 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.1 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160)
0.0 0.9 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.4 GO:0019673 GDP-mannose metabolic process(GO:0019673)
0.0 0.2 GO:0009597 detection of virus(GO:0009597)
0.0 0.3 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 2.0 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.2 GO:0002232 leukocyte chemotaxis involved in inflammatory response(GO:0002232) positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.0 0.4 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.5 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.5 GO:1900086 positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
0.0 0.9 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.1 GO:0002355 detection of tumor cell(GO:0002355)
0.0 0.3 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.7 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.2 GO:0071494 cellular response to UV-C(GO:0071494)
0.0 0.2 GO:0002248 connective tissue replacement involved in inflammatory response wound healing(GO:0002248)
0.0 1.2 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.5 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 0.3 GO:0097475 motor neuron migration(GO:0097475)
0.0 1.2 GO:0033522 histone H2A ubiquitination(GO:0033522)
0.0 0.2 GO:0060356 leucine import(GO:0060356)
0.0 0.5 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.2 GO:0035087 targeting of mRNA for destruction involved in RNA interference(GO:0030423) siRNA loading onto RISC involved in RNA interference(GO:0035087) small RNA loading onto RISC(GO:0070922)
0.0 0.4 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.4 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.4 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.0 0.2 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 0.3 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0 0.1 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0 0.9 GO:1903427 negative regulation of reactive oxygen species biosynthetic process(GO:1903427)
0.0 0.3 GO:0009644 response to high light intensity(GO:0009644)
0.0 0.3 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0002344 peripheral B cell selection(GO:0002343) B cell affinity maturation(GO:0002344)
0.0 0.1 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.4 GO:0000052 citrulline metabolic process(GO:0000052)
0.0 0.5 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.6 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.0 GO:0010636 positive regulation of mitochondrial fusion(GO:0010636)
0.0 0.4 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.2 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.2 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.0 0.1 GO:0030450 regulation of complement activation, classical pathway(GO:0030450)
0.0 0.3 GO:0061034 succinyl-CoA metabolic process(GO:0006104) olfactory bulb mitral cell layer development(GO:0061034)
0.0 0.3 GO:0008300 isoprenoid catabolic process(GO:0008300)
0.0 0.1 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.0 0.1 GO:0000963 mitochondrial RNA processing(GO:0000963)
0.0 0.1 GO:0090346 nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210) cellular organohalogen metabolic process(GO:0090345) cellular organofluorine metabolic process(GO:0090346)
0.0 0.3 GO:1900103 positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.0 0.7 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 0.2 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.0 0.3 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 0.6 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.0 0.9 GO:0000132 establishment of mitotic spindle orientation(GO:0000132)
0.0 0.4 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.2 GO:0045842 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.9 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0 0.5 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 1.0 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.2 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719) glucagon secretion(GO:0070091) regulation of glucagon secretion(GO:0070092)
0.0 0.2 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.2 GO:0032099 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.0 1.3 GO:0001702 gastrulation with mouth forming second(GO:0001702)
0.0 1.8 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.2 GO:0060309 elastin catabolic process(GO:0060309)
0.0 0.2 GO:0036006 response to macrophage colony-stimulating factor(GO:0036005) cellular response to macrophage colony-stimulating factor stimulus(GO:0036006)
0.0 0.1 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.0 0.4 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 1.8 GO:0042274 ribosomal small subunit biogenesis(GO:0042274)
0.0 0.5 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 2.1 GO:0016126 sterol biosynthetic process(GO:0016126)
0.0 0.2 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.2 GO:0006083 acetate metabolic process(GO:0006083)
0.0 0.3 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.3 GO:0021554 optic nerve development(GO:0021554)
0.0 1.7 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.1 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.3 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.1 GO:0090222 centrosome-templated microtubule nucleation(GO:0090222)
0.0 0.0 GO:0006393 termination of mitochondrial transcription(GO:0006393)
0.0 0.4 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.1 GO:0097045 activation of blood coagulation via clotting cascade(GO:0002543) phosphatidylserine exposure on blood platelet(GO:0097045)
0.0 0.1 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.2 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.8 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.5 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.3 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.4 GO:0007398 ectoderm development(GO:0007398)
0.0 0.3 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.3 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.3 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.1 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.0 0.2 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 8.5 GO:0008380 RNA splicing(GO:0008380)
0.0 1.0 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.2 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0 0.9 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.2 GO:1900242 regulation of synaptic vesicle endocytosis(GO:1900242)
0.0 0.1 GO:0009188 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188) inosine biosynthetic process(GO:0046103)
0.0 0.2 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.1 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.1 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.2 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.0 GO:1902177 positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902177)
0.0 0.1 GO:0032826 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.0 0.3 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.3 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.0 GO:0045643 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.0 0.5 GO:0021511 spinal cord patterning(GO:0021511)
0.0 0.1 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.6 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.3 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.4 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 1.0 GO:0042509 regulation of tyrosine phosphorylation of STAT protein(GO:0042509)
0.0 0.6 GO:0014003 oligodendrocyte development(GO:0014003)
0.0 0.1 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.3 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 1.1 GO:0008033 tRNA processing(GO:0008033)
0.0 0.1 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.1 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.3 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.5 GO:0042168 heme metabolic process(GO:0042168)
0.0 0.0 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.4 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.4 GO:0051642 centrosome localization(GO:0051642)
0.0 0.1 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 1.5 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.2 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.2 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.4 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.0 0.4 GO:0042026 protein refolding(GO:0042026)
0.0 0.2 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.1 GO:0061734 negative regulation of receptor recycling(GO:0001920) parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.0 0.1 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.3 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.0 0.6 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.7 GO:0007041 lysosomal transport(GO:0007041)
0.0 0.1 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.1 GO:1990000 amyloid fibril formation(GO:1990000)
0.0 0.1 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.0 0.2 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.0 GO:1903920 positive regulation of actin filament severing(GO:1903920)
0.0 0.2 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.2 GO:0006085 acetyl-CoA biosynthetic process(GO:0006085)
0.0 0.4 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 0.1 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.1 GO:0070836 caveola assembly(GO:0070836)
0.0 0.3 GO:0042572 retinol metabolic process(GO:0042572)
0.0 1.0 GO:0050658 nucleic acid transport(GO:0050657) RNA transport(GO:0050658)
0.0 0.1 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.1 GO:0044331 cell-cell adhesion mediated by cadherin(GO:0044331)
0.0 0.3 GO:0030225 macrophage differentiation(GO:0030225)
0.0 0.4 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.0 GO:0035854 regulation of primitive erythrocyte differentiation(GO:0010725) basophil differentiation(GO:0030221) eosinophil fate commitment(GO:0035854)
0.0 0.1 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.0 0.1 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 0.2 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 0.1 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
1.1 3.4 GO:0031904 endosome lumen(GO:0031904)
0.8 2.3 GO:0097144 BAX complex(GO:0097144)
0.5 1.8 GO:0005745 m-AAA complex(GO:0005745)
0.4 2.4 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.4 5.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.4 1.4 GO:0071821 FANCM-MHF complex(GO:0071821)
0.3 0.9 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.3 1.4 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.3 0.8 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.3 2.0 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.2 1.5 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.2 3.0 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.2 0.9 GO:0032021 NELF complex(GO:0032021)
0.2 0.7 GO:0034456 CURI complex(GO:0032545) UTP-C complex(GO:0034456)
0.2 0.9 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.2 0.6 GO:0000814 ESCRT II complex(GO:0000814)
0.2 0.8 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.2 1.0 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.2 1.0 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.2 1.2 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.2 1.0 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.2 1.6 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.2 1.0 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.2 1.3 GO:0033503 HULC complex(GO:0033503)
0.2 1.4 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.2 2.7 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.2 1.1 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 1.9 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 2.0 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 1.0 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 0.7 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 1.2 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 1.3 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 2.5 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 0.4 GO:0097132 cyclin D2-CDK6 complex(GO:0097132)
0.1 1.1 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 2.4 GO:0032039 integrator complex(GO:0032039)
0.1 1.9 GO:0044754 autolysosome(GO:0044754)
0.1 2.0 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.1 0.4 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.1 1.2 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.1 0.8 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.1 2.3 GO:0005682 U5 snRNP(GO:0005682)
0.1 0.5 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.1 1.3 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.1 1.3 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 0.4 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.1 0.3 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.1 2.5 GO:0005686 U2 snRNP(GO:0005686)
0.1 0.4 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.1 0.5 GO:0000439 core TFIIH complex(GO:0000439)
0.1 0.2 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.1 1.3 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.1 1.1 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.5 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.1 0.5 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.1 0.6 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 0.5 GO:1903439 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.1 1.0 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 0.5 GO:0034719 SMN-Sm protein complex(GO:0034719)
0.1 2.3 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 1.4 GO:0042405 nuclear inclusion body(GO:0042405)
0.1 0.4 GO:0097452 GAIT complex(GO:0097452)
0.1 0.6 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1 0.4 GO:0035339 SPOTS complex(GO:0035339)
0.1 0.5 GO:0089701 U2AF(GO:0089701)
0.1 0.2 GO:0005760 gamma DNA polymerase complex(GO:0005760)
0.1 3.8 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 0.5 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1 0.8 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.5 GO:0042825 TAP complex(GO:0042825)
0.1 0.3 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1 0.3 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 0.8 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 0.3 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.5 GO:0070545 PeBoW complex(GO:0070545)
0.1 0.8 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 0.6 GO:0061574 ASAP complex(GO:0061574)
0.1 0.3 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 0.4 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 0.3 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.1 0.5 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.7 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 0.5 GO:0042382 paraspeckles(GO:0042382)
0.1 0.2 GO:0097447 dendritic tree(GO:0097447)
0.1 0.6 GO:0031415 NatA complex(GO:0031415)
0.1 1.4 GO:0035253 ciliary rootlet(GO:0035253)
0.1 0.8 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 0.4 GO:0030891 VCB complex(GO:0030891)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.2 GO:0034455 t-UTP complex(GO:0034455)
0.1 0.4 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 0.8 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 3.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.7 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 1.2 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 1.0 GO:0030914 STAGA complex(GO:0030914)
0.0 0.2 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.5 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.7 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 2.4 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.1 GO:0000799 nuclear condensin complex(GO:0000799)
0.0 1.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.5 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 2.5 GO:0008180 COP9 signalosome(GO:0008180)
0.0 1.4 GO:0001741 XY body(GO:0001741)
0.0 0.4 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.6 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.8 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.2 GO:0000938 GARP complex(GO:0000938) EARP complex(GO:1990745)
0.0 1.0 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.3 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.3 GO:0070652 HAUS complex(GO:0070652)
0.0 0.9 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.4 GO:0005869 dynactin complex(GO:0005869)
0.0 2.4 GO:0005643 nuclear pore(GO:0005643)
0.0 0.5 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.8 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 4.5 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.6 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.3 GO:0005688 U6 snRNP(GO:0005688)
0.0 2.6 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.2 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.6 GO:0031143 pseudopodium(GO:0031143)
0.0 0.5 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.7 GO:0031528 microvillus membrane(GO:0031528)
0.0 1.0 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 1.7 GO:0001772 immunological synapse(GO:0001772)
0.0 0.3 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 2.3 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 1.0 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.3 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.4 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.9 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.2 GO:0032807 DNA ligase IV complex(GO:0032807)
0.0 0.6 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.5 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.4 GO:0032009 early phagosome(GO:0032009)
0.0 0.2 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.3 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 1.0 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.6 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.3 GO:0097418 neurofibrillary tangle(GO:0097418)
0.0 0.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.4 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 0.3 GO:0030684 preribosome(GO:0030684)
0.0 0.4 GO:0033202 DNA helicase complex(GO:0033202)
0.0 0.2 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 1.4 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 8.2 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.4 GO:0001891 phagocytic cup(GO:0001891)
0.0 1.4 GO:0005761 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.0 0.3 GO:0070852 cell body fiber(GO:0070852)
0.0 0.3 GO:0001939 female pronucleus(GO:0001939)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 0.2 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.7 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 1.3 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.6 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.1 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.2 GO:0000801 central element(GO:0000801)
0.0 0.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.6 GO:0015030 Cajal body(GO:0015030)
0.0 0.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.1 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 1.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.2 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.5 GO:0005840 ribosome(GO:0005840)
0.0 0.1 GO:0036449 microtubule minus-end(GO:0036449)
0.0 18.1 GO:0005739 mitochondrion(GO:0005739)
0.0 0.2 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.4 GO:0031201 SNARE complex(GO:0031201)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.4 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.5 1.4 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.4 1.8 GO:0016842 amidine-lyase activity(GO:0016842)
0.4 1.5 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.4 1.1 GO:0004372 glycine hydroxymethyltransferase activity(GO:0004372)
0.3 1.0 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.3 1.0 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.3 5.7 GO:0046977 TAP binding(GO:0046977)
0.3 0.9 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.3 0.9 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.3 0.9 GO:0042015 interleukin-20 binding(GO:0042015)
0.3 1.2 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.3 0.8 GO:0031177 phosphopantetheine binding(GO:0031177)
0.3 0.8 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426)
0.3 1.0 GO:0033797 selenate reductase activity(GO:0033797)
0.2 1.0 GO:0036470 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478)
0.2 1.0 GO:0098770 FBXO family protein binding(GO:0098770)
0.2 1.5 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.2 1.0 GO:0003998 acylphosphatase activity(GO:0003998)
0.2 2.3 GO:0051434 BH3 domain binding(GO:0051434)
0.2 0.7 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.2 1.1 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761)
0.2 1.7 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.2 0.8 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.2 0.6 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.2 1.0 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.2 0.6 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.2 1.0 GO:0030620 U2 snRNA binding(GO:0030620)
0.2 2.6 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.2 1.0 GO:0004074 biliverdin reductase activity(GO:0004074)
0.2 0.6 GO:0070401 NADP+ binding(GO:0070401)
0.2 1.3 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.2 0.5 GO:0050785 advanced glycation end-product receptor activity(GO:0050785)
0.2 0.5 GO:0004948 calcitonin receptor activity(GO:0004948)
0.2 1.2 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.2 1.0 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.2 1.7 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.2 1.5 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.2 0.3 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.2 0.5 GO:0004560 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.2 1.0 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.2 0.9 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.2 2.0 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 0.4 GO:0030622 U4atac snRNA binding(GO:0030622)
0.1 1.0 GO:0019808 polyamine binding(GO:0019808)
0.1 0.4 GO:0070336 flap-structured DNA binding(GO:0070336)
0.1 0.8 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.1 0.5 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 0.4 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.1 0.9 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.1 1.0 GO:0019158 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 1.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 0.5 GO:0032093 SAM domain binding(GO:0032093)
0.1 0.4 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.1 0.6 GO:0001032 RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.1 0.7 GO:0031750 D3 dopamine receptor binding(GO:0031750)
0.1 0.4 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.1 0.4 GO:1990932 5.8S rRNA binding(GO:1990932)
0.1 0.7 GO:0016807 cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004)
0.1 2.5 GO:0016805 dipeptidase activity(GO:0016805)
0.1 1.5 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.1 0.7 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.1 0.4 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1 1.2 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 0.3 GO:0036004 GAF domain binding(GO:0036004)
0.1 0.5 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.1 0.3 GO:0004794 L-threonine ammonia-lyase activity(GO:0004794)
0.1 1.3 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.1 0.4 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.1 0.3 GO:0052692 raffinose alpha-galactosidase activity(GO:0052692)
0.1 1.9 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.3 GO:0008413 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.1 0.7 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.1 0.6 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.4 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.1 1.3 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 0.3 GO:0005302 L-tyrosine transmembrane transporter activity(GO:0005302)
0.1 0.4 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.1 1.0 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.6 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 1.0 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.1 0.4 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441)
0.1 0.3 GO:0008988 rRNA (adenine-N6-)-methyltransferase activity(GO:0008988)
0.1 0.8 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.1 0.3 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)
0.1 0.7 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.4 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.1 0.2 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1 0.2 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.1 0.2 GO:0019153 protein-disulfide reductase (glutathione) activity(GO:0019153)
0.1 2.2 GO:0015036 disulfide oxidoreductase activity(GO:0015036)
0.1 0.7 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.1 2.2 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 0.3 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.1 0.2 GO:0032767 copper-dependent protein binding(GO:0032767)
0.1 0.3 GO:0019970 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.1 0.3 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.1 0.7 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.3 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.3 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.1 0.2 GO:0019150 D-ribulokinase activity(GO:0019150)
0.1 0.3 GO:0000010 trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347)
0.1 1.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.9 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.1 0.5 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.1 0.4 GO:0034618 arginine binding(GO:0034618)
0.1 0.7 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 1.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.6 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.4 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 3.2 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 0.3 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.1 0.7 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 1.1 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.2 GO:0019807 aspartoacylase activity(GO:0019807)
0.1 0.3 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 0.3 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 0.3 GO:0008097 5S rRNA binding(GO:0008097)
0.1 1.5 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 1.4 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.4 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 1.0 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 0.3 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.1 1.9 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 0.7 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.3 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 1.4 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 1.0 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 1.0 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.7 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.6 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 1.0 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 0.3 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.5 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.4 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.7 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.4 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.3 GO:0004849 uridine kinase activity(GO:0004849)
0.0 1.3 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.5 GO:0051870 methotrexate binding(GO:0051870)
0.0 0.2 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.2 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.0 0.4 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.4 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 2.9 GO:0008186 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 0.2 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.0 1.2 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.2 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.4 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.6 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.8 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.4 GO:0000150 recombinase activity(GO:0000150)
0.0 1.9 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 1.7 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 1.2 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.2 GO:0072354 histone kinase activity (H3-T3 specific)(GO:0072354)
0.0 0.2 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.3 GO:0043559 insulin binding(GO:0043559)
0.0 1.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.8 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.4 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.8 GO:0070628 proteasome binding(GO:0070628)
0.0 0.5 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 1.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.2 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.3 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 1.9 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.9 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.3 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.7 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 2.4 GO:0051287 NAD binding(GO:0051287)
0.0 6.6 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.5 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.3 GO:0070717 poly-purine tract binding(GO:0070717)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.3 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.9 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.2 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.3 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.0 1.4 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.3 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.9 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.8 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.1 GO:0016708 nitric oxide dioxygenase activity(GO:0008941) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor(GO:0016708) iron-cytochrome-c reductase activity(GO:0047726)
0.0 0.6 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.0 3.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.9 GO:0015295 solute:proton symporter activity(GO:0015295)
0.0 0.2 GO:0015923 mannosidase activity(GO:0015923)
0.0 1.1 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.6 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.2 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.2 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.3 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.4 GO:0008301 DNA binding, bending(GO:0008301)
0.0 1.5 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.0 0.2 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958) cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.2 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.5 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.6 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.1 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.4 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.4 GO:0015926 glucosidase activity(GO:0015926)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 1.0 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.2 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 1.0 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.3 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.1 GO:0000403 Y-form DNA binding(GO:0000403)
0.0 0.1 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.8 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.6 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.7 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.2 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.2 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.2 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.1 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019)
0.0 0.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319) sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.2 GO:0043996 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.4 GO:0035325 Toll-like receptor binding(GO:0035325)
0.0 0.8 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.0 0.6 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.5 GO:0008432 JUN kinase binding(GO:0008432)
0.0 1.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.8 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 0.1 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.4 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.4 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.2 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.6 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.0 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.0 0.2 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.1 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.1 GO:0034452 dynactin binding(GO:0034452)
0.0 0.1 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.0 0.5 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.3 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 0.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.9 GO:0048029 monosaccharide binding(GO:0048029)
0.0 0.1 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.5 GO:0000049 tRNA binding(GO:0000049)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.9 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.3 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.1 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.2 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.8 GO:0043492 ATPase activity, coupled to movement of substances(GO:0043492)
0.0 0.3 GO:0008252 nucleotidase activity(GO:0008252)
0.0 0.8 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.5 GO:0050699 WW domain binding(GO:0050699)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.7 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.9 GO:0051087 chaperone binding(GO:0051087)
0.0 0.8 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.1 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.1 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.6 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 2.9 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 0.6 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 2.5 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 3.6 PID ATR PATHWAY ATR signaling pathway
0.1 1.6 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.1 2.3 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.7 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 2.2 PID AURORA A PATHWAY Aurora A signaling
0.0 1.6 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.9 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.4 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.3 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.4 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 1.1 PID AURORA B PATHWAY Aurora B signaling
0.0 0.7 PID IL5 PATHWAY IL5-mediated signaling events
0.0 1.1 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.6 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 1.3 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 2.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.4 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.4 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 1.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.4 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.8 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.5 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.6 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.2 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.1 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.4 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.5 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.3 PID EPO PATHWAY EPO signaling pathway
0.0 0.5 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.6 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.7 PID RAC1 REG PATHWAY Regulation of RAC1 activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.7 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.2 5.6 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 3.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 0.5 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.1 1.9 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 0.2 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 1.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 6.1 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1 3.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 1.6 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 1.9 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 2.1 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 2.7 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 1.6 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.1 1.5 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 1.3 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.1 0.7 REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism
0.1 2.6 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 4.1 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.1 0.8 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 2.7 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 1.1 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 1.4 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 2.1 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 0.7 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 0.3 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.1 0.8 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.1 0.2 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.1 0.9 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 1.0 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 0.5 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 1.7 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 1.0 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 1.1 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 3.4 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.0 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 1.0 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 1.1 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.4 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.5 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.9 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 1.3 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.0 1.5 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 3.0 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 2.6 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.7 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 2.1 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.9 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 5.2 REACTOME TRANSLATION Genes involved in Translation
0.0 0.6 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 4.4 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.9 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.1 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.0 0.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.8 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.5 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.4 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.5 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 2.8 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.4 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.3 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.1 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.9 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.6 REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.0 1.0 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.2 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.9 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.8 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.2 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.9 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.3 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.6 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.6 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 1.2 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.4 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.0 0.5 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.3 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.5 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.5 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.3 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 1.2 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.2 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.4 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 2.8 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.9 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 0.0 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.3 REACTOME KINESINS Genes involved in Kinesins
0.0 0.1 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.2 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.4 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.6 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 0.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction