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avrg: GFI1 WT vs 36n/n vs KD

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Results for Pitx3

Z-value: 0.68

Motif logo

Transcription factors associated with Pitx3

Gene Symbol Gene ID Gene Info
ENSMUSG00000025229.16 paired-like homeodomain transcription factor 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pitx3mm39_v1_chr19_-_46136765_461368250.405.0e-01Click!

Activity profile of Pitx3 motif

Sorted Z-values of Pitx3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_47074617 0.77 ENSMUST00000041012.9
pre T cell antigen receptor alpha
chr5_+_90907207 0.62 ENSMUST00000031318.6
chemokine (C-X-C motif) ligand 5
chr2_+_87609827 0.61 ENSMUST00000105210.3
olfactory receptor 152
chr2_-_121211410 0.57 ENSMUST00000038389.15
stereocilin
chr5_+_138278777 0.57 ENSMUST00000048028.15
ENSMUST00000162245.8
ENSMUST00000161691.2
stromal antigen 3
chr1_-_16163506 0.52 ENSMUST00000145070.8
ENSMUST00000151004.2
RIKEN cDNA 4930444P10 gene
chr12_+_44268134 0.47 ENSMUST00000122902.8
patatin-like phospholipase domain containing 8
chr5_-_125201872 0.46 ENSMUST00000055256.14
nuclear receptor co-repressor 2
chr11_+_87295860 0.46 ENSMUST00000060835.12
testis expressed gene 14
chr3_-_152045986 0.44 ENSMUST00000199397.2
ENSMUST00000199334.5
ENSMUST00000068243.11
ENSMUST00000073089.13
mitoguardin 1
chr16_+_36004452 0.42 ENSMUST00000114858.2
cystatin domain containing 4
chr8_-_106485201 0.41 ENSMUST00000155038.3
ENSMUST00000013294.16
glucose-fructose oxidoreductase domain containing 2
chr16_-_91415873 0.41 ENSMUST00000143058.2
ENSMUST00000049244.10
ENSMUST00000169982.2
ENSMUST00000133731.2
DnaJ heat shock protein family (Hsp40) member C28
chr7_-_106605189 0.40 ENSMUST00000216375.2
ENSMUST00000208147.3
olfactory receptor 2
chr7_+_28834276 0.39 ENSMUST00000161522.8
ENSMUST00000204845.3
ENSMUST00000205027.3
ENSMUST00000204194.3
ENSMUST00000203070.3
ENSMUST00000203380.3
RAS guanyl releasing protein 4
chr7_+_67925718 0.39 ENSMUST00000210558.2
family with sequence similarity 169, member B
chr16_+_32090286 0.38 ENSMUST00000093183.5
single-pass membrane protein with coiled-coil domains 1
chr9_-_44352312 0.38 ENSMUST00000215980.2
ENSMUST00000098837.3
forkhead box R1
chr14_+_14159978 0.37 ENSMUST00000137133.2
ENSMUST00000036070.15
ENSMUST00000121887.8
family with sequence similarity 107, member A
chr17_-_35407403 0.37 ENSMUST00000097336.5
leukocyte specific transcript 1
chr17_+_49735386 0.37 ENSMUST00000165390.9
ENSMUST00000024797.16
molybdenum cofactor synthesis 1
chr4_-_155729865 0.37 ENSMUST00000115821.3
predicted gene 10563
chr9_+_119186447 0.37 ENSMUST00000039610.10
xylulokinase homolog (H. influenzae)
chr1_+_92900834 0.37 ENSMUST00000186298.7
ENSMUST00000027489.9
G protein-coupled receptor 35
chr7_+_16726633 0.36 ENSMUST00000094805.5
coiled-coil domain containing 8
chr11_+_117673107 0.36 ENSMUST00000050874.14
ENSMUST00000106334.9
transmembrane channel-like gene family 8
chr7_+_28834350 0.35 ENSMUST00000159975.8
ENSMUST00000094617.11
ENSMUST00000032811.12
RAS guanyl releasing protein 4
chrX_+_7775781 0.35 ENSMUST00000086274.3
predicted gene 10490
chr14_-_51134930 0.35 ENSMUST00000227271.2
kelch-like 33
chr16_-_38162174 0.35 ENSMUST00000114740.3
cilia and flagella associated protein 91
chr2_-_165242307 0.35 ENSMUST00000029213.5
osteoclast stimulatory transmembrane protein
chr4_+_132903646 0.34 ENSMUST00000105912.2
WASP family, member 2
chr17_-_32408431 0.34 ENSMUST00000087721.10
ENSMUST00000162117.3
epoxide hydrolase 3
chr3_-_105839980 0.33 ENSMUST00000098758.5
RIKEN cDNA I830077J02 gene
chr6_+_42326714 0.33 ENSMUST00000203846.3
zyxin
chr11_-_58614840 0.32 ENSMUST00000214728.2
olfactory receptor 318
chr17_+_35286293 0.31 ENSMUST00000173478.2
ENSMUST00000174876.2
lymphocyte antigen 6 complex, locus G6C
chr5_-_142891565 0.31 ENSMUST00000171419.8
actin, beta
chr10_-_85847697 0.31 ENSMUST00000105304.2
ENSMUST00000061699.12
BPI fold containing family C
chr7_+_28834391 0.31 ENSMUST00000160194.8
RAS guanyl releasing protein 4
chr3_+_105778174 0.30 ENSMUST00000164730.2
ENSMUST00000010279.10
adenosine A3 receptor
transmembrane and immunoglobulin domain containing 3
chr7_-_19621833 0.30 ENSMUST00000052605.8
carcinoembryonic antigen-related cell adhesion molecule 19
chr8_-_71257623 0.30 ENSMUST00000212875.2
ENSMUST00000212001.2
ENSMUST00000212757.2
microtubule associated serine/threonine kinase 3
chr2_+_113271409 0.29 ENSMUST00000081349.9
formin 1
chr1_-_39690642 0.29 ENSMUST00000053355.6
cellular repressor of E1A-stimulated genes 2
chr17_-_32491339 0.29 ENSMUST00000237008.2
bromodomain containing 4
chr17_+_49735413 0.28 ENSMUST00000173033.8
molybdenum cofactor synthesis 1
chr8_+_66419809 0.28 ENSMUST00000072482.13
membrane associated ring-CH-type finger 1
chr15_+_101191099 0.28 ENSMUST00000191426.2
small integral membrane protein 41
chrY_+_818646 0.28 ENSMUST00000190013.7
ENSMUST00000115894.3
ubiquitin-activating enzyme, Chr Y
chr15_-_84804239 0.28 ENSMUST00000189185.2
predicted gene 29666
chr6_+_122803624 0.28 ENSMUST00000203075.2
forkhead box J2
chr2_+_113235475 0.28 ENSMUST00000238883.2
formin 1
chr3_+_105811712 0.28 ENSMUST00000000574.3
adenosine A3 receptor
chr6_+_57183497 0.27 ENSMUST00000227298.2
vomeronasal 1 receptor 13
chr5_+_137516810 0.27 ENSMUST00000197624.5
GRB10 interacting GYF protein 1
chr1_+_174251630 0.27 ENSMUST00000192358.3
olfactory receptor 414
chr2_-_172300516 0.27 ENSMUST00000099060.2
glucosaminyl (N-acetyl) transferase family member 7
chr11_-_58437248 0.27 ENSMUST00000219448.2
olfactory receptor 329
chr11_+_101932328 0.26 ENSMUST00000123895.8
ENSMUST00000017453.12
ENSMUST00000107163.9
ENSMUST00000107164.3
CD300 molecule like family member G
chr14_-_52516695 0.26 ENSMUST00000167116.8
ENSMUST00000100631.11
RAB2B, member RAS oncogene family
chr7_+_18573879 0.26 ENSMUST00000072415.9
ENSMUST00000072386.11
ENSMUST00000228493.2
ENSMUST00000227379.2
MHC I like leukocyte 2
chr9_-_88974735 0.25 ENSMUST00000189557.2
ENSMUST00000167113.8
tripartite motif-containing 43B
chr9_+_107457316 0.24 ENSMUST00000093785.6
N(alpha)-acetyltransferase 80, NatH catalytic subunit
chr12_-_87742525 0.24 ENSMUST00000164517.3
eukaryotic translation initiation factor 1A domain containing 19
chrX_+_35375751 0.23 ENSMUST00000033418.8
interleukin 13 receptor, alpha 1
chr5_-_138153956 0.23 ENSMUST00000132318.2
ENSMUST00000049393.15
zinc finger protein 113
chr16_-_36154692 0.23 ENSMUST00000114850.3
cystatin domain containing 6
chr4_-_132191181 0.22 ENSMUST00000102567.4
mediator complex subunit 18
chr12_-_72675624 0.22 ENSMUST00000208039.2
ENSMUST00000207585.2
predicted gene 4756
chr1_-_78488795 0.22 ENSMUST00000170511.3
cDNA sequence BC035947
chr13_-_100453124 0.22 ENSMUST00000042220.3
NLR family, apoptosis inhibitory protein 6
chr2_-_127050161 0.22 ENSMUST00000056146.2
RIKEN cDNA 1810024B03 gene
chr9_+_109760528 0.22 ENSMUST00000035055.15
microtubule-associated protein 4
chr2_-_26184450 0.22 ENSMUST00000217256.2
ENSMUST00000227200.2
coiled-coil domain containing 187
chr6_+_42326980 0.22 ENSMUST00000203849.2
zyxin
chr2_+_165834546 0.21 ENSMUST00000109252.8
ENSMUST00000088095.6
nuclear receptor coactivator 3
chr5_+_107977965 0.21 ENSMUST00000072578.8
ubiquitin-conjugating enzyme E2D 2B
chr13_-_100240570 0.21 ENSMUST00000038104.12
B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
chr6_-_149090146 0.21 ENSMUST00000095319.10
ENSMUST00000141346.2
ENSMUST00000111535.8
antagonist of mitotic exit network 1
chr8_-_70963202 0.21 ENSMUST00000125184.8
ubiquitin A-52 residue ribosomal protein fusion product 1
chr14_+_54598283 0.21 ENSMUST00000000985.7
oxidase assembly 1-like
chr7_+_5037117 0.21 ENSMUST00000076791.4
RIKEN cDNA 4632433K11 gene
chr10_+_81442717 0.21 ENSMUST00000119753.8
ENSMUST00000121138.2
ENSMUST00000099442.4
cDNA sequence BC025920
chr6_+_42326934 0.21 ENSMUST00000203401.3
ENSMUST00000164375.4
zyxin
chr11_-_103247150 0.20 ENSMUST00000136491.3
ENSMUST00000107023.3
Rho GTPase activating protein 27
chr3_-_36107661 0.20 ENSMUST00000166644.8
ENSMUST00000200469.5
coiled-coil domain containing 144B
chr11_-_116021936 0.20 ENSMUST00000106440.9
ENSMUST00000067632.4
tripartite motif-containing 65
chr8_+_123103348 0.20 ENSMUST00000017622.12
ENSMUST00000093073.12
ENSMUST00000176699.2
zinc finger CCCH-type containing 18
chr11_-_58353096 0.20 ENSMUST00000215691.2
olfactory receptor 30
chr18_+_31937129 0.20 ENSMUST00000082319.15
ENSMUST00000234957.2
ENSMUST00000025264.8
ENSMUST00000234344.2
WD repeat domain 33
chr10_-_68114543 0.20 ENSMUST00000219238.2
AT rich interactive domain 5B (MRF1-like)
chr15_+_76763431 0.20 ENSMUST00000023179.7
zinc finger protein 7
chr8_+_123103415 0.20 ENSMUST00000176629.8
zinc finger CCCH-type containing 18
chr11_-_62348599 0.20 ENSMUST00000127471.9
nuclear receptor co-repressor 1
chr6_+_42326760 0.20 ENSMUST00000203652.3
ENSMUST00000070635.13
zyxin
chr2_-_119371994 0.20 ENSMUST00000171024.8
exonuclease 3'-5' domain containing 1
chr19_+_23736205 0.20 ENSMUST00000025830.9
amyloid beta (A4) precursor protein binding, family A, member 1
chr7_+_4918199 0.20 ENSMUST00000116354.4
zinc finger protein 628
chr5_-_62923463 0.20 ENSMUST00000076623.8
ENSMUST00000159470.3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr7_-_15361801 0.20 ENSMUST00000086122.10
ENSMUST00000174443.8
oocyte specific homeobox 3
chr9_+_44398524 0.19 ENSMUST00000218183.2
B cell CLL/lymphoma 9-like
chr7_-_6699422 0.19 ENSMUST00000122432.4
ENSMUST00000002336.16
zinc finger, imprinted 1
chr5_-_143831842 0.19 ENSMUST00000079624.12
ENSMUST00000110717.9
ankyrin repeat domain 61
chr11_-_54846873 0.19 ENSMUST00000155316.2
ENSMUST00000108889.10
ENSMUST00000126703.8
TNFAIP3 interacting protein 1
chr7_-_127331338 0.19 ENSMUST00000206038.2
cardiotrophin 2
chr6_+_137387718 0.19 ENSMUST00000167002.4
protein tyrosine phosphatase, receptor type, O
chr6_-_71121347 0.19 ENSMUST00000160918.8
threonine synthase-like 2 (bacterial)
chrX_-_9335525 0.19 ENSMUST00000015484.10
cytochrome b-245, beta polypeptide
chr5_-_137609691 0.19 ENSMUST00000031731.14
procollagen C-endopeptidase enhancer protein
chr11_-_4110286 0.19 ENSMUST00000093381.11
ENSMUST00000101626.9
coiled-coil domain containing 157
chr15_-_58828321 0.19 ENSMUST00000228067.2
MTSS I-BAR domain containing 1
chr9_-_29874401 0.18 ENSMUST00000075069.11
neurotrimin
chr2_-_125602234 0.18 ENSMUST00000139944.2
SECIS binding protein 2-like
chr11_-_57983936 0.18 ENSMUST00000218429.2
ENSMUST00000219877.2
predicted gene 12248
chr8_-_84996976 0.18 ENSMUST00000005120.12
ENSMUST00000163993.2
ENSMUST00000098578.10
coiled-coil domain containing 130
chr1_-_5140504 0.18 ENSMUST00000147158.2
ENSMUST00000118000.8
regulator of G-protein signaling 20
chr15_+_102368510 0.18 ENSMUST00000164688.2
proline rich 13
chr2_-_32631028 0.18 ENSMUST00000009695.3
RIKEN cDNA 6330409D20 gene
chr6_+_113369377 0.18 ENSMUST00000032414.11
ENSMUST00000038889.12
tubulin tyrosine ligase-like family, member 3
chr9_-_119897358 0.18 ENSMUST00000064165.5
chemokine (C-X3-C motif) receptor 1
chr11_+_6339061 0.18 ENSMUST00000109787.8
zinc finger, MIZ-type containing 2
chr14_-_79628106 0.18 ENSMUST00000022597.15
N(alpha)-acetyltransferase 16, NatA auxiliary subunit
chr4_+_143833044 0.18 ENSMUST00000097800.9
ENSMUST00000097799.9
ENSMUST00000105761.4
predicted gene 13102
chr8_-_3517617 0.18 ENSMUST00000111081.10
ENSMUST00000004686.13
peroxisomal biogenesis factor 11 gamma
chr5_+_122781941 0.18 ENSMUST00000100737.10
ENSMUST00000121489.8
ENSMUST00000031425.15
ENSMUST00000086247.6
purinergic receptor P2X, ligand-gated ion channel, 7
chr7_-_19338349 0.18 ENSMUST00000086041.7
CLK4-associating serine/arginine rich protein
chr7_+_12615091 0.17 ENSMUST00000144578.2
zinc finger protein 128
chr17_-_6129968 0.17 ENSMUST00000024570.6
ENSMUST00000097432.10
serine active site containing 1
chr10_-_60532250 0.17 ENSMUST00000105464.9
ENSMUST00000105463.9
ENSMUST00000105461.10
cadherin 23 (otocadherin)
chr14_+_26761023 0.17 ENSMUST00000223942.2
interleukin 17 receptor D
chr9_+_18848418 0.17 ENSMUST00000218385.2
olfactory receptor 832
chr9_-_107512511 0.17 ENSMUST00000192615.6
ENSMUST00000192837.2
ENSMUST00000193876.2
guanine nucleotide binding protein (G protein), alpha inhibiting 2
chr7_+_126528016 0.17 ENSMUST00000032924.6
potassium channel tetramerisation domain containing 13
chr9_-_119897328 0.17 ENSMUST00000177637.2
chemokine (C-X3-C motif) receptor 1
chr9_-_107512566 0.17 ENSMUST00000055704.12
guanine nucleotide binding protein (G protein), alpha inhibiting 2
chr8_-_65582206 0.16 ENSMUST00000098713.5
small integral membrane protein 31
chr12_+_4893303 0.16 ENSMUST00000220215.2
ENSMUST00000223551.2
ENSMUST00000053034.6
ENSMUST00000220170.2
WD repeat and coiled coil containing
chr10_+_127226180 0.16 ENSMUST00000077046.12
ENSMUST00000105250.9
R3H domain containing 2
chr9_+_88721217 0.16 ENSMUST00000163255.9
ENSMUST00000186363.2
tripartite motif-containing 43C
chr5_+_34683141 0.16 ENSMUST00000125817.8
ENSMUST00000067638.14
SH3-domain binding protein 2
chr14_+_54380308 0.16 ENSMUST00000196323.2
T cell receptor delta, constant region
chr3_-_113423774 0.16 ENSMUST00000092154.10
ENSMUST00000106536.8
ENSMUST00000106535.2
RNA-binding region (RNP1, RRM) containing 3
chr1_+_171052623 0.16 ENSMUST00000111321.8
ENSMUST00000005824.12
ENSMUST00000111320.8
ENSMUST00000111319.2
apolipoprotein A-II
chr6_+_137387729 0.16 ENSMUST00000203914.2
protein tyrosine phosphatase, receptor type, O
chr2_-_25517945 0.16 ENSMUST00000028307.9
ficolin A
chr13_+_49761506 0.16 ENSMUST00000021822.7
osteoglycin
chr4_+_143792268 0.16 ENSMUST00000084191.3
ENSMUST00000094520.5
PRAME like 4
chr5_-_86320599 0.15 ENSMUST00000039373.14
ubiquitin-like modifier activating enzyme 6
chr7_-_19426529 0.15 ENSMUST00000207978.2
ENSMUST00000108451.4
ENSMUST00000045035.12
apolipoprotein C-I
chr7_+_75351713 0.15 ENSMUST00000207239.2
A kinase (PRKA) anchor protein 13
chr11_+_96822213 0.15 ENSMUST00000107633.2
proline rich 15-like
chr7_+_118196518 0.15 ENSMUST00000098088.11
ENSMUST00000121715.8
transmembrane channel-like gene family 5
chr12_-_85143852 0.15 ENSMUST00000177289.9
prospero homeobox 2
chr8_-_41087793 0.15 ENSMUST00000173957.2
ENSMUST00000048898.17
ENSMUST00000174205.8
myotubularin related protein 7
chr2_+_79538124 0.15 ENSMUST00000090760.9
ENSMUST00000040863.11
ENSMUST00000111780.3
protein phosphatase 1, regulatory inhibitor subunit 1C
chr1_-_175806680 0.15 ENSMUST00000104983.2
RNA binding motif protein 8A2
chr18_-_49888606 0.15 ENSMUST00000025383.10
ENSMUST00000163590.9
DTW domain containing 2
chr2_-_29983618 0.15 ENSMUST00000081838.7
ENSMUST00000102865.11
zinc finger, DHHC domain containing 12
chr10_-_71121083 0.15 ENSMUST00000020085.7
ubiquitin-conjugating enzyme E2D 1
chr7_-_104991477 0.15 ENSMUST00000213290.2
olfactory receptor 691
chr19_-_47525437 0.14 ENSMUST00000182808.8
ENSMUST00000182714.2
ENSMUST00000049369.16
STN1, CST complex subunit
chr1_-_184615415 0.14 ENSMUST00000048308.6
RIKEN cDNA C130074G19 gene
chr5_-_116162415 0.14 ENSMUST00000031486.14
ENSMUST00000111999.8
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr17_+_24768808 0.14 ENSMUST00000228550.2
ENSMUST00000035565.5
polycystin 1, transient receptor poteintial channel interacting
chr17_+_56259617 0.14 ENSMUST00000003274.8
Epstein-Barr virus induced gene 3
chr9_-_49710058 0.14 ENSMUST00000192584.2
ENSMUST00000166811.9
neural cell adhesion molecule 1
chr5_-_137475326 0.14 ENSMUST00000117564.8
zonadhesin
chr11_+_117673198 0.14 ENSMUST00000117781.8
transmembrane channel-like gene family 8
chr7_-_15701395 0.14 ENSMUST00000144956.2
ENSMUST00000098799.5
EH-domain containing 2
chr10_-_81436671 0.14 ENSMUST00000151858.8
ENSMUST00000142948.8
ENSMUST00000072020.9
transducin-like enhancer of split 6
chr1_-_74002156 0.14 ENSMUST00000191367.2
tensin 1
chr15_+_99936516 0.13 ENSMUST00000100203.10
disco interacting protein 2 homolog B
chr4_+_138503046 0.13 ENSMUST00000030528.9
phospholipase A2, group IID
chr1_-_139304779 0.13 ENSMUST00000196402.5
ENSMUST00000059825.12
crumbs family member 1, photoreceptor morphogenesis associated
chr5_-_137609634 0.13 ENSMUST00000054564.13
procollagen C-endopeptidase enhancer protein
chr5_-_137015683 0.13 ENSMUST00000034953.14
ENSMUST00000085941.12
zinc finger, HIT domain containing 1
chr7_+_27252658 0.13 ENSMUST00000067386.14
ENSMUST00000191126.7
ENSMUST00000187960.7
RIKEN cDNA 2310022A10 gene
chr1_+_192890015 0.13 ENSMUST00000194677.6
ENSMUST00000192322.6
laminin, beta 3
chr10_+_128061699 0.13 ENSMUST00000026455.8
major intrinsic protein of lens fiber
chr9_-_21710029 0.13 ENSMUST00000034717.7
KN motif and ankyrin repeat domains 2
chr4_+_47386216 0.13 ENSMUST00000107725.3
transforming growth factor, beta receptor I
chr6_-_99412306 0.13 ENSMUST00000113322.9
ENSMUST00000176850.8
ENSMUST00000176632.8
forkhead box P1
chr4_+_43441939 0.13 ENSMUST00000060864.13
testis specific protein kinase 1
chr2_-_121304521 0.13 ENSMUST00000056732.4
microfibrillar-associated protein 1B
chr11_+_120563844 0.12 ENSMUST00000106158.9
ENSMUST00000103016.8
ENSMUST00000168714.9
alveolar soft part sarcoma chromosome region, candidate 1 (human)
chr7_+_45204350 0.12 ENSMUST00000210300.2
hydroxysteroid (17-beta) dehydrogenase 14
chr7_+_25318829 0.12 ENSMUST00000077338.12
ENSMUST00000085953.5
distal membrane arm assembly complex 2
chr3_-_88363027 0.12 ENSMUST00000029700.12
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr7_-_100164007 0.12 ENSMUST00000207405.2
DnaJ heat shock protein family (Hsp40) member B13
chr14_+_66872699 0.12 ENSMUST00000159365.8
ENSMUST00000054661.8
ENSMUST00000225182.2
ENSMUST00000159068.2
adrenergic receptor, alpha 1a
chr2_-_166902307 0.12 ENSMUST00000155281.8
zinc finger, NFX1-type containing 1
chr2_-_132420047 0.12 ENSMUST00000028822.14
glycerophosphocholine phosphodiesterase 1
chr3_-_88363704 0.12 ENSMUST00000141471.2
ENSMUST00000123753.8
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr17_+_34354556 0.12 ENSMUST00000236322.2
ENSMUST00000237402.2
histocompatibility 2, class II, locus DMa
chr5_+_3621673 0.12 ENSMUST00000008451.12
RIKEN cDNA 1700109H08 gene
chr7_-_44854316 0.12 ENSMUST00000121017.5
KASH domain containing 5
chr9_-_49710190 0.12 ENSMUST00000114476.8
ENSMUST00000193547.6
neural cell adhesion molecule 1
chr11_-_69435382 0.12 ENSMUST00000035539.12
dynein, axonemal, heavy chain 2
chr8_+_72704882 0.12 ENSMUST00000131237.8
ENSMUST00000136516.9
ENSMUST00000109997.10
ENSMUST00000132848.2
zinc finger protein 961

Network of associatons between targets according to the STRING database.

First level regulatory network of Pitx3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0070948 regulation of neutrophil mediated cytotoxicity(GO:0070948) regulation of neutrophil mediated killing of symbiont cell(GO:0070949)
0.2 0.5 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.1 0.4 GO:1904456 negative regulation of neuronal action potential(GO:1904456)
0.1 0.6 GO:0007066 female meiosis sister chromatid cohesion(GO:0007066)
0.1 0.5 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.1 0.3 GO:0002545 chronic inflammatory response to non-antigenic stimulus(GO:0002545) regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002880)
0.1 0.3 GO:0042732 D-xylose metabolic process(GO:0042732)
0.1 0.3 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.1 0.3 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.1 0.3 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 0.3 GO:0090290 positive regulation of macrophage fusion(GO:0034241) positive regulation of osteoclast proliferation(GO:0090290)
0.1 0.7 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.1 0.6 GO:0072092 ureteric bud invasion(GO:0072092)
0.1 0.3 GO:0035963 response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963)
0.1 0.5 GO:0032466 negative regulation of cytokinesis(GO:0032466)
0.1 0.3 GO:0001928 regulation of exocyst assembly(GO:0001928)
0.1 0.2 GO:1904172 positive regulation of bleb assembly(GO:1904172)
0.1 0.6 GO:0002553 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.1 0.2 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.2 GO:0072362 regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362)
0.0 0.7 GO:0070244 negative regulation of thymocyte apoptotic process(GO:0070244)
0.0 0.1 GO:0060854 patterning of lymph vessels(GO:0060854)
0.0 0.3 GO:0050689 negative regulation of defense response to virus by host(GO:0050689)
0.0 0.1 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.1 GO:1905223 epicardium morphogenesis(GO:1905223)
0.0 0.2 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.0 0.2 GO:1900110 negative regulation of histone H3-K9 dimethylation(GO:1900110)
0.0 0.1 GO:0002396 MHC protein complex assembly(GO:0002396) peptide antigen assembly with MHC protein complex(GO:0002501)
0.0 0.2 GO:0010901 regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
0.0 0.1 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0 0.2 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0 0.1 GO:0034727 lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) suppression by virus of host autophagy(GO:0039521) amino acid homeostasis(GO:0080144) negative regulation of sphingolipid biosynthesis involved in cellular sphingolipid homeostasis(GO:0090157)
0.0 0.1 GO:0070104 negative regulation of interleukin-6-mediated signaling pathway(GO:0070104)
0.0 0.1 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.0 0.2 GO:0044375 regulation of peroxisome size(GO:0044375)
0.0 0.1 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.0 0.2 GO:0006566 threonine metabolic process(GO:0006566)
0.0 0.1 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.0 0.1 GO:1904582 positive regulation of intracellular mRNA localization(GO:1904582)
0.0 0.2 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.2 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.1 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.1 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.0 0.2 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.4 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.2 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.1 GO:1901074 regulation of engulfment of apoptotic cell(GO:1901074)
0.0 0.7 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.1 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
0.0 0.2 GO:0042695 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0 0.2 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.1 GO:0036233 glycine import(GO:0036233)
0.0 0.1 GO:0061623 UDP-glucose metabolic process(GO:0006011) glycolytic process from galactose(GO:0061623)
0.0 0.1 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.1 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.0 0.3 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.1 GO:2000359 regulation of binding of sperm to zona pellucida(GO:2000359)
0.0 0.0 GO:0048320 axial mesoderm formation(GO:0048320)
0.0 0.1 GO:1990743 protein sialylation(GO:1990743)
0.0 0.2 GO:0021764 amygdala development(GO:0021764)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.1 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.0 0.2 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:0070859 positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.0 0.3 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 0.2 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.2 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.1 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.0 0.1 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.2 GO:0070269 pyroptosis(GO:0070269)
0.0 0.1 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.1 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0 0.1 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.0 GO:1905006 positive regulation of activation-induced cell death of T cells(GO:0070237) negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905006)
0.0 0.1 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.0 0.1 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.1 GO:0035878 nail development(GO:0035878)
0.0 0.1 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.2 GO:0060613 fat pad development(GO:0060613)
0.0 1.1 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579)
0.0 0.4 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.0 0.0 GO:0008594 photoreceptor cell morphogenesis(GO:0008594)
0.0 0.0 GO:0002625 regulation of T cell antigen processing and presentation(GO:0002625)
0.0 0.0 GO:1902045 regulation of Fas signaling pathway(GO:1902044) negative regulation of Fas signaling pathway(GO:1902045)
0.0 0.1 GO:1901355 response to rapamycin(GO:1901355)
0.0 0.3 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.1 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.1 0.6 GO:0000802 transverse filament(GO:0000802)
0.1 0.2 GO:1990879 CST complex(GO:1990879)
0.1 0.4 GO:1990393 3M complex(GO:1990393)
0.1 0.7 GO:0060091 kinocilium(GO:0060091)
0.0 0.1 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.1 GO:0046691 intracellular canaliculus(GO:0046691)
0.0 0.2 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.0 0.2 GO:1990923 PET complex(GO:1990923)
0.0 0.2 GO:0070847 core mediator complex(GO:0070847)
0.0 0.1 GO:0005668 RNA polymerase transcription factor SL1 complex(GO:0005668)
0.0 0.4 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 0.3 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.1 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.3 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.2 GO:0097255 R2TP complex(GO:0097255)
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.2 GO:0090576 RNA polymerase III transcription factor complex(GO:0090576)
0.0 0.1 GO:0097443 sorting endosome(GO:0097443)
0.0 0.3 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.0 GO:0070992 translation initiation complex(GO:0070992)
0.0 0.1 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.0 0.1 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.2 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.2 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.1 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0098973 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.1 0.4 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.2 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.1 0.3 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
0.1 0.6 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.6 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.5 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.2 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.0 0.2 GO:0070736 protein-glycine ligase activity, initiating(GO:0070736)
0.0 0.2 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.2 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.3 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.0 0.1 GO:0019778 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.0 0.1 GO:0019981 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.0 0.4 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.1 GO:0033680 ATP-dependent DNA/RNA helicase activity(GO:0033680) triplex DNA binding(GO:0045142)
0.0 0.1 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.2 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.2 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.1 GO:0052593 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.0 0.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.1 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.1 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.2 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.2 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.0 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.0 0.1 GO:0097001 ceramide binding(GO:0097001)
0.0 0.0 GO:0070698 type I activin receptor binding(GO:0070698)
0.0 0.2 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.1 GO:0070905 serine binding(GO:0070905)
0.0 0.2 GO:0001164 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.3 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.2 GO:0043047 single-stranded telomeric DNA binding(GO:0043047)
0.0 0.1 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.1 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 0.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.5 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.1 GO:0070287 ferritin receptor activity(GO:0070287)
0.0 0.1 GO:0016936 galactoside binding(GO:0016936)
0.0 0.1 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.1 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.6 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.2 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.9 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.4 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.2 PID S1P S1P4 PATHWAY S1P4 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.6 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.6 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.8 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 1.0 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.3 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.1 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.6 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.1 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.1 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK