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avrg: GFI1 WT vs 36n/n vs KD

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Results for Plag1

Z-value: 1.44

Motif logo

Transcription factors associated with Plag1

Gene Symbol Gene ID Gene Info
ENSMUSG00000003282.10 pleiomorphic adenoma gene 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Plag1mm39_v1_chr4_-_3938352_39384010.533.6e-01Click!

Activity profile of Plag1 motif

Sorted Z-values of Plag1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr13_+_23947641 1.38 ENSMUST00000055770.4
H1.1 linker histone, cluster member
chr19_+_53131187 1.37 ENSMUST00000050096.15
ENSMUST00000237832.2
adducin 3 (gamma)
chr12_-_45120895 1.22 ENSMUST00000120531.8
ENSMUST00000143376.8
syntaxin binding protein 6 (amisyn)
chr14_-_33700719 1.02 ENSMUST00000166737.2
zinc finger protein 488
chrX_-_71318353 0.99 ENSMUST00000064780.4
gamma-aminobutyric acid (GABA) A receptor, subunit epsilon
chr16_-_4031814 0.97 ENSMUST00000023165.9
CREB binding protein
chr6_-_48422307 0.92 ENSMUST00000114563.8
ENSMUST00000114558.8
ENSMUST00000101443.10
zinc finger protein 467
chr6_-_116693849 0.92 ENSMUST00000056623.13
transmembrane protein 72
chr7_+_100355910 0.84 ENSMUST00000207875.2
ENSMUST00000208013.2
family with sequence similarity 168, member A
chr2_-_91854844 0.78 ENSMUST00000028663.5
cAMP responsive element binding protein 3-like 1
chr6_-_48422612 0.77 ENSMUST00000114556.2
zinc finger protein 467
chr7_+_5023552 0.76 ENSMUST00000208728.2
ENSMUST00000085427.6
coiled-coil domain containing 106
zinc finger protein 865
chr11_+_105858764 0.73 ENSMUST00000001963.14
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
chr12_-_99378855 0.71 ENSMUST00000177269.2
forkhead box N3
chr6_-_48422759 0.61 ENSMUST00000114561.9
zinc finger protein 467
chr7_-_19426529 0.61 ENSMUST00000207978.2
ENSMUST00000108451.4
ENSMUST00000045035.12
apolipoprotein C-I
chr10_+_58649181 0.58 ENSMUST00000135526.9
ENSMUST00000153031.2
SH3 domain containing ring finger 3
chr2_-_104324035 0.57 ENSMUST00000111124.8
homeodomain interacting protein kinase 3
chr8_-_84299540 0.57 ENSMUST00000212990.2
trans-2,3-enoyl-CoA reductase
chr7_-_123099672 0.54 ENSMUST00000042470.14
ENSMUST00000128217.2
zinc finger with KRAB and SCAN domains 2
chr19_+_10502612 0.53 ENSMUST00000237321.2
ENSMUST00000038379.5
cleavage and polyadenylation specific factor 7
chr8_-_107064615 0.52 ENSMUST00000067512.8
sphingomyelin phosphodiesterase 3, neutral
chr5_-_90031180 0.52 ENSMUST00000198151.2
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 3
chr11_-_97877219 0.52 ENSMUST00000107565.3
ENSMUST00000107564.2
ENSMUST00000017561.15
plexin domain containing 1
chr7_-_140590605 0.51 ENSMUST00000026565.7
interferon induced transmembrane protein 3
chr10_+_60185093 0.51 ENSMUST00000105459.2
V-set immunoregulatory receptor
chr15_-_101268036 0.51 ENSMUST00000077196.6
keratin 80
chr15_-_76084035 0.50 ENSMUST00000054449.14
ENSMUST00000169714.8
ENSMUST00000165453.8
plectin
chr2_-_5719302 0.48 ENSMUST00000044009.14
calcium/calmodulin-dependent protein kinase ID
chr19_+_10502679 0.48 ENSMUST00000235674.2
cleavage and polyadenylation specific factor 7
chr5_-_142891686 0.46 ENSMUST00000106216.3
actin, beta
chrX_-_165368675 0.46 ENSMUST00000000412.3
EGF-like-domain, multiple 6
chr15_-_76501041 0.46 ENSMUST00000073428.7
solute carrier family 39 (zinc transporter), member 4
chr11_+_115078299 0.46 ENSMUST00000100235.9
ENSMUST00000061450.7
transmembrane protein 104
chr3_-_95041246 0.45 ENSMUST00000172572.9
ENSMUST00000173462.3
sodium channel modifier 1
chr7_+_4795873 0.45 ENSMUST00000032597.12
ENSMUST00000078432.5
ribosomal protein L28
chr2_-_34261121 0.45 ENSMUST00000127353.3
ENSMUST00000141653.3
pre B cell leukemia homeobox 3
chr9_+_59658156 0.44 ENSMUST00000136740.8
ENSMUST00000135298.8
ENSMUST00000128341.2
myosin IXa
chr2_+_3514071 0.44 ENSMUST00000036350.3
cerebral dopamine neurotrophic factor
chr15_-_82783978 0.43 ENSMUST00000230403.2
transcription factor 20
chr11_-_69586626 0.42 ENSMUST00000108649.3
ENSMUST00000174159.8
ENSMUST00000181810.8
tumor necrosis factor (ligand) superfamily, membrane-bound member 13
tumor necrosis factor (ligand) superfamily, member 12
chr9_+_45924120 0.42 ENSMUST00000120463.9
ENSMUST00000120247.8
SIK family kinase 3
chr17_-_34340918 0.42 ENSMUST00000151986.2
bromodomain containing 2
chr7_-_15781838 0.41 ENSMUST00000210781.2
BRD4 interacting chromatin remodeling complex associated protein
chr2_-_24365607 0.41 ENSMUST00000028355.11
paired box 8
chr11_+_98754434 0.41 ENSMUST00000142414.8
ENSMUST00000037480.9
WAS/WASL interacting protein family, member 2
chr7_+_5023375 0.40 ENSMUST00000076251.7
zinc finger protein 865
chr1_-_74130488 0.40 ENSMUST00000187584.7
tensin 1
chr1_+_92900834 0.39 ENSMUST00000186298.7
ENSMUST00000027489.9
G protein-coupled receptor 35
chr19_+_10819896 0.38 ENSMUST00000025646.3
solute carrier family 15, member 3
chr12_-_101879375 0.37 ENSMUST00000177536.8
ENSMUST00000176728.2
ENSMUST00000021605.14
thyroid hormone receptor interactor 11
chr3_+_88049875 0.37 ENSMUST00000107558.9
ENSMUST00000107559.3
myocyte enhancer factor 2D
chr15_-_76082346 0.37 ENSMUST00000072692.11
plectin
chr19_-_61216834 0.37 ENSMUST00000076046.7
colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
chr9_+_108394005 0.37 ENSMUST00000195563.6
glutamine-rich 1
chr14_+_58308004 0.37 ENSMUST00000165526.9
fibroblast growth factor 9
chr4_+_124880223 0.37 ENSMUST00000030687.8
R-spondin 1
chr7_+_3352019 0.37 ENSMUST00000100301.11
protein kinase C, gamma
chr1_-_5089564 0.36 ENSMUST00000002533.15
regulator of G-protein signaling 20
chr3_+_95041399 0.36 ENSMUST00000066386.6
LysM, putative peptidoglycan-binding, domain containing 1
chr10_+_59057767 0.36 ENSMUST00000182161.2
sosondowah ankyrin repeat domain family member C
chr7_-_100581314 0.36 ENSMUST00000107032.3
Rho guanine nucleotide exchange factor (GEF) 17
chr15_-_50753437 0.36 ENSMUST00000077935.6
transcriptional repressor GATA binding 1
chrX_+_95139639 0.36 ENSMUST00000117399.2
moesin
chr2_-_172782089 0.35 ENSMUST00000009143.8
bone morphogenetic protein 7
chr6_-_146403638 0.34 ENSMUST00000079573.13
inositol 1,4,5-triphosphate receptor 2
chr4_-_41569500 0.34 ENSMUST00000108049.9
ENSMUST00000108052.10
ENSMUST00000108050.2
family with sequence similarity 219, member A
chr9_-_97915036 0.34 ENSMUST00000162295.2
calsyntenin 2
chr8_+_3671528 0.34 ENSMUST00000156380.4
PET100 homolog
chr4_-_63321591 0.33 ENSMUST00000035724.5
AT-hook transcription factor
chr9_+_44398524 0.33 ENSMUST00000218183.2
B cell CLL/lymphoma 9-like
chrX_-_132882514 0.33 ENSMUST00000113297.9
ENSMUST00000174542.2
ENSMUST00000033608.15
ENSMUST00000113294.8
synaptotagmin-like 4
chr11_+_29323618 0.32 ENSMUST00000040182.13
ENSMUST00000109477.2
coiled coil domain containing 88A
chr4_+_132701413 0.32 ENSMUST00000030693.13
FGR proto-oncogene, Src family tyrosine kinase
chr6_+_122929410 0.32 ENSMUST00000117173.8
C-type lectin domain family 4, member a3
chr6_-_52190299 0.32 ENSMUST00000128102.4
predicted gene 28308
chr10_-_126877382 0.32 ENSMUST00000116231.4
EEF1A lysine methyltransferase 3
chr9_+_20193647 0.32 ENSMUST00000071725.4
ENSMUST00000212983.3
olfactory receptor 39
chr3_+_105821450 0.31 ENSMUST00000198080.5
ENSMUST00000199977.2
transmembrane and immunoglobulin domain containing 3
chr17_-_7652863 0.31 ENSMUST00000070059.5
unc-93 homolog A2
chr14_-_30850795 0.31 ENSMUST00000049732.11
ENSMUST00000090205.5
ENSMUST00000064032.10
small integral membrane protein 4
chrX_-_20157966 0.30 ENSMUST00000115393.3
ENSMUST00000072451.11
solute carrier family 9 (sodium/hydrogen exchanger), member 7
chr15_+_78784043 0.30 ENSMUST00000001226.11
SH3-domain binding protein 1
chr7_-_43182595 0.29 ENSMUST00000205503.2
CD33 antigen
chr2_+_172090412 0.29 ENSMUST00000038532.2
melanocortin 3 receptor
chr7_-_97958679 0.29 ENSMUST00000033020.14
alkaline ceramidase 3
chr7_+_24583994 0.29 ENSMUST00000108428.8
ribosomal protein S19
chr6_-_113172340 0.29 ENSMUST00000162280.2
lipoma HMGIC fusion partner-like protein 4
chr7_+_100355798 0.29 ENSMUST00000107042.9
ENSMUST00000207564.2
ENSMUST00000049053.9
family with sequence similarity 168, member A
chr7_-_126294902 0.28 ENSMUST00000144897.2
SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)
chr7_+_126295114 0.28 ENSMUST00000106369.2
bolA-like 2 (E. coli)
chr9_+_56979307 0.28 ENSMUST00000169879.8
transcriptional regulator, SIN3A (yeast)
chr16_-_85347305 0.28 ENSMUST00000175700.8
ENSMUST00000114174.3
cysteine and tyrosine-rich protein 1
chr3_-_133250889 0.28 ENSMUST00000197118.5
tet methylcytosine dioxygenase 2
chr6_-_99005835 0.28 ENSMUST00000154163.9
forkhead box P1
chr2_-_172961168 0.28 ENSMUST00000094287.10
ENSMUST00000179693.2
CCCTC-binding factor (zinc finger protein)-like
chr7_+_140641010 0.28 ENSMUST00000048002.7
beta-1,4-N-acetyl-galactosaminyl transferase 4
chr2_-_45007407 0.28 ENSMUST00000176438.9
zinc finger E-box binding homeobox 2
chr7_-_127837154 0.28 ENSMUST00000078816.5
RIKEN cDNA 9130023H24 gene
chr17_-_23964807 0.28 ENSMUST00000046525.10
kringle containing transmembrane protein 2
chr11_-_104441218 0.27 ENSMUST00000106962.9
ENSMUST00000106961.2
ENSMUST00000093923.9
cell division cycle 27
chr17_-_57366795 0.27 ENSMUST00000040280.14
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
chr7_+_28466160 0.27 ENSMUST00000122915.8
ENSMUST00000072965.5
ENSMUST00000170068.9
sirtuin 2
chrX_+_93278588 0.27 ENSMUST00000096369.10
ENSMUST00000113911.9
kelch-like 15
chr8_+_129085719 0.27 ENSMUST00000026917.10
neuropilin 1
chr11_+_59432388 0.27 ENSMUST00000079476.10
NLR family, pyrin domain containing 3
chr7_+_78563964 0.27 ENSMUST00000120331.4
interferon-stimulated protein
chr15_-_76083575 0.27 ENSMUST00000169438.8
plectin
chr8_-_85500998 0.27 ENSMUST00000109762.8
nuclear factor I/X
chr9_+_102885156 0.27 ENSMUST00000035148.13
solute carrier organic anion transporter family, member 2a1
chr11_-_116021936 0.27 ENSMUST00000106440.9
ENSMUST00000067632.4
tripartite motif-containing 65
chr1_+_132119169 0.26 ENSMUST00000188169.7
ENSMUST00000112357.9
ENSMUST00000188175.2
LEM domain containing 1
predicted gene, 29695
chr7_-_28824440 0.26 ENSMUST00000214374.2
ENSMUST00000179893.9
ENSMUST00000032813.10
ryanodine receptor 1, skeletal muscle
chr7_+_79675727 0.26 ENSMUST00000049680.10
zinc finger protein 710
chrX_-_135769285 0.26 ENSMUST00000058814.7
RAB9B, member RAS oncogene family
chr9_+_21458138 0.26 ENSMUST00000034703.15
ENSMUST00000115395.10
ENSMUST00000115394.8
coactivator-associated arginine methyltransferase 1
chr8_+_72993862 0.26 ENSMUST00000003117.15
ENSMUST00000212841.2
adaptor-related protein complex AP-1, mu subunit 1
chr7_+_27879650 0.26 ENSMUST00000172467.8
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr6_-_142453531 0.26 ENSMUST00000134191.3
ENSMUST00000239397.2
ENSMUST00000239395.2
ENSMUST00000032373.12
lactate dehydrogenase B
chr15_+_81469538 0.26 ENSMUST00000068387.11
E1A binding protein p300
chr7_+_104210108 0.25 ENSMUST00000219111.2
ENSMUST00000215410.2
ENSMUST00000216131.2
olfactory receptor 652
chr11_+_70431063 0.25 ENSMUST00000018429.12
ENSMUST00000108557.10
ENSMUST00000108556.2
phospholipase D2
chr4_+_123798690 0.25 ENSMUST00000106202.4
MYC binding protein
chr3_-_96501443 0.25 ENSMUST00000145001.2
ENSMUST00000091924.10
polymerase (RNA) III (DNA directed) polypeptide G like
chr4_-_128699838 0.25 ENSMUST00000106072.9
ENSMUST00000170934.3
zinc finger protein 362
chr2_+_146063841 0.25 ENSMUST00000089257.6
insulinoma-associated 1
chr17_-_35340189 0.25 ENSMUST00000025246.13
ENSMUST00000173114.8
casein kinase 2, beta polypeptide
chr1_+_37338964 0.25 ENSMUST00000027287.11
ENSMUST00000140264.8
inositol polyphosphate-4-phosphatase, type I
chr19_+_44191704 0.25 ENSMUST00000026220.7
stearoyl-coenzyme A desaturase 3
chr19_+_5348329 0.25 ENSMUST00000061169.7
galactose-3-O-sulfotransferase 3
chrX_-_97934387 0.25 ENSMUST00000113826.8
ENSMUST00000033560.9
ENSMUST00000142267.2
oligophrenin 1
chr17_-_35392254 0.25 ENSMUST00000025257.12
allograft inflammatory factor 1
chr19_-_10434837 0.24 ENSMUST00000171400.4
leucine rich repeat containing 10B
chr11_+_103061905 0.24 ENSMUST00000042286.12
ENSMUST00000218163.2
formin-like 1
chr19_-_43974990 0.24 ENSMUST00000026210.5
carboxypeptidase N, polypeptide 1
chr7_+_128213084 0.24 ENSMUST00000043138.13
inositol polyphosphate-5-phosphatase F
chr6_-_142910094 0.24 ENSMUST00000032421.4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr12_+_40495951 0.24 ENSMUST00000037488.8
dedicator of cytokinesis 4
chr11_+_93886906 0.24 ENSMUST00000041956.14
sperm associated antigen 9
chr12_-_70394074 0.24 ENSMUST00000223160.2
ENSMUST00000222316.2
ENSMUST00000167755.3
ENSMUST00000110520.10
ENSMUST00000110522.10
ENSMUST00000221041.2
ENSMUST00000222603.3
tripartite motif-containing 9
chr7_-_48530777 0.24 ENSMUST00000058745.15
E2F transcription factor 8
chr15_+_101164719 0.24 ENSMUST00000230814.2
ENSMUST00000023779.8
nuclear receptor subfamily 4, group A, member 1
chr11_+_78006391 0.23 ENSMUST00000155571.2
family with sequence similarity 222, member B
chr10_-_12745109 0.23 ENSMUST00000218635.2
utrophin
chr16_+_51852435 0.23 ENSMUST00000227879.2
Casitas B-lineage lymphoma b
chr2_-_153083322 0.23 ENSMUST00000056924.14
pleiomorphic adenoma gene-like 2
chr6_-_48422447 0.23 ENSMUST00000114564.8
zinc finger protein 467
chr8_+_107409765 0.23 ENSMUST00000211979.2
transport and golgi organization 6
chr9_+_100525807 0.23 ENSMUST00000133388.2
stromal antigen 1
chrX_-_107877909 0.23 ENSMUST00000101283.4
ENSMUST00000150434.8
bromodomain and WD repeat domain containing 3
chr6_+_124986224 0.23 ENSMUST00000112427.8
zinc finger protein 384
chr6_+_124986078 0.23 ENSMUST00000054553.11
zinc finger protein 384
chr8_-_106198112 0.23 ENSMUST00000014990.13
tubulin polymerization-promoting protein family member 3
chr4_+_40269563 0.23 ENSMUST00000129758.3
small integral membrane protein 27
chr6_-_48818302 0.23 ENSMUST00000203355.3
ENSMUST00000166247.8
transmembrane protein 176B
chr2_+_29779227 0.23 ENSMUST00000123335.8
outer dense fiber of sperm tails 2
chr9_-_51076724 0.22 ENSMUST00000210433.2
predicted gene, 32742
chr19_-_34618135 0.22 ENSMUST00000087357.5
interferon induced protein with tetratricopeptide repeats 1B like 2
chr13_-_115238427 0.22 ENSMUST00000224997.2
ENSMUST00000061673.9
predicted gene, 49395
integrin alpha 1
chr12_-_91556761 0.22 ENSMUST00000021345.14
general transcription factor II A, 1
chr2_+_14078958 0.22 ENSMUST00000028050.14
signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
chr4_+_122889737 0.22 ENSMUST00000106252.9
v-myc avian myelocytomatosis viral oncogene lung carcinoma derived
chr19_+_6130059 0.22 ENSMUST00000149347.8
ENSMUST00000143303.2
transmembrane protein 262
chr10_-_69048928 0.22 ENSMUST00000170048.2
RIKEN cDNA A930033H14 gene
chr9_+_109760931 0.22 ENSMUST00000165876.8
microtubule-associated protein 4
chr7_-_28297565 0.22 ENSMUST00000040531.9
ENSMUST00000108283.8
sterile alpha motif domain containing 4B
p21 (RAC1) activated kinase 4
chr16_-_36695166 0.21 ENSMUST00000075946.12
ELL associated factor 2
chrX_+_7523499 0.21 ENSMUST00000033485.14
prickle planar cell polarity protein 3
chr16_-_91415873 0.21 ENSMUST00000143058.2
ENSMUST00000049244.10
ENSMUST00000169982.2
ENSMUST00000133731.2
DnaJ heat shock protein family (Hsp40) member C28
chr12_-_4891435 0.21 ENSMUST00000219880.2
ENSMUST00000020964.7
FK506 binding protein 1b
chr2_-_25873189 0.21 ENSMUST00000114167.9
ENSMUST00000091268.11
ENSMUST00000183461.8
calmodulin regulated spectrin-associated protein 1
chr11_+_29324348 0.21 ENSMUST00000239407.2
coiled coil domain containing 88A
chr7_+_102954855 0.21 ENSMUST00000214577.2
olfactory receptor 596
chr19_-_10502468 0.21 ENSMUST00000025570.8
ENSMUST00000236455.2
succinate dehydrogenase complex assembly factor 2
chr11_+_101151394 0.21 ENSMUST00000103108.8
WNK lysine deficient protein kinase 4
chr1_-_155912159 0.21 ENSMUST00000097527.10
torsin A interacting protein 1
chr9_-_70410611 0.21 ENSMUST00000215848.2
ENSMUST00000113595.2
ENSMUST00000213647.2
ring finger 111
chr7_-_44888532 0.21 ENSMUST00000033063.15
CD37 antigen
chrX_-_101114906 0.21 ENSMUST00000188731.2
retrotransposon Gag like 5
chr6_-_33037107 0.21 ENSMUST00000115091.2
ENSMUST00000127666.8
coiled-coil-helix-coiled-coil-helix domain containing 3
chr9_+_108394269 0.20 ENSMUST00000195513.6
ENSMUST00000193258.6
ENSMUST00000112155.9
ENSMUST00000006851.15
glutamine-rich 1
chr8_-_70573465 0.20 ENSMUST00000002412.9
neurocan
chr7_-_35285001 0.20 ENSMUST00000069912.6
regulator of G-protein signalling 9 binding protein
chr5_-_120726721 0.20 ENSMUST00000046426.10
two pore channel 1
chr9_-_100453102 0.20 ENSMUST00000093792.4
solute carrier family 35, member G2
chr17_+_84013575 0.20 ENSMUST00000112350.8
ENSMUST00000112349.9
ENSMUST00000112352.10
ENSMUST00000067826.15
metastasis associated 3
chr5_+_114427227 0.20 ENSMUST00000169347.6
myosin 1H
chr19_-_5713701 0.20 ENSMUST00000164304.9
ENSMUST00000237544.2
signal-induced proliferation associated gene 1
chr9_-_70411000 0.20 ENSMUST00000034739.12
ring finger 111
chr15_-_50753061 0.20 ENSMUST00000165201.9
ENSMUST00000184458.8
transcriptional repressor GATA binding 1
chr15_-_98560739 0.20 ENSMUST00000162384.2
ENSMUST00000003450.15
DEAD box helicase 23
chr2_-_160208977 0.20 ENSMUST00000099126.5
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)
chr2_+_156681991 0.20 ENSMUST00000073352.10
TGFB-induced factor homeobox 2
chr5_+_97145533 0.20 ENSMUST00000112974.6
ENSMUST00000035635.10
BMP2 inducible kinase
chr6_-_87312743 0.20 ENSMUST00000042025.12
ENSMUST00000205033.2
anthrax toxin receptor 1
chr2_-_150510116 0.19 ENSMUST00000028944.4
acyl-CoA synthetase short-chain family member 1
chr1_-_171910324 0.19 ENSMUST00000003550.11
nicastrin
chr11_+_119158829 0.19 ENSMUST00000026666.13
ENSMUST00000106258.2
glucosidase, alpha, acid
chr7_+_46045862 0.19 ENSMUST00000025202.8
potassium voltage gated channel, Shaw-related subfamily, member 1
chr1_-_171023798 0.19 ENSMUST00000111332.2
Purkinje cell protein 4-like 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Plag1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:1905051 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.2 0.7 GO:2000170 positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
0.2 1.0 GO:0045358 negative regulation of interferon-beta biosynthetic process(GO:0045358)
0.2 1.5 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.2 0.8 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.2 0.5 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.1 0.4 GO:2000612 regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.1 0.4 GO:1904456 negative regulation of neuronal action potential(GO:1904456)
0.1 0.4 GO:2000777 positive regulation of oocyte maturation(GO:1900195) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.1 0.4 GO:0036118 hyaluranon cable assembly(GO:0036118) nephrogenic mesenchyme development(GO:0072076) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.1 0.6 GO:0090154 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.1 0.3 GO:1904431 positive regulation of t-circle formation(GO:1904431)
0.1 0.3 GO:0043181 vacuolar sequestering(GO:0043181)
0.1 0.5 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.1 0.3 GO:0003358 noradrenergic neuron development(GO:0003358)
0.1 0.3 GO:0097374 cell migration involved in vasculogenesis(GO:0035441) neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) sensory neuron axon guidance(GO:0097374)
0.1 0.5 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.1 0.3 GO:0034970 histone H3-R2 methylation(GO:0034970)
0.1 0.3 GO:0030070 insulin processing(GO:0030070)
0.1 0.5 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.1 0.4 GO:0014735 regulation of muscle atrophy(GO:0014735)
0.1 0.3 GO:0061350 planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354)
0.1 0.2 GO:0014739 positive regulation of muscle hyperplasia(GO:0014739)
0.1 0.2 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.1 0.8 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.1 0.2 GO:0034378 chylomicron assembly(GO:0034378)
0.1 1.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.2 GO:0098749 cerebellar neuron development(GO:0098749)
0.1 0.4 GO:0042631 cellular response to water deprivation(GO:0042631)
0.1 0.3 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.1 0.3 GO:0019858 cytosine metabolic process(GO:0019858)
0.1 0.3 GO:0097274 urea homeostasis(GO:0097274)
0.1 0.1 GO:0060667 fibroblast growth factor receptor signaling pathway involved in mammary gland specification(GO:0060595) mammary gland bud formation(GO:0060615) branch elongation involved in salivary gland morphogenesis(GO:0060667) mesenchymal cell differentiation involved in lung development(GO:0060915)
0.1 0.5 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.1 0.3 GO:2000321 positive regulation of T-helper 17 cell differentiation(GO:2000321)
0.1 0.1 GO:0060594 mammary gland specification(GO:0060594)
0.1 0.2 GO:0019413 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate biosynthetic process(GO:0019542)
0.1 0.3 GO:0097032 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.1 0.2 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 0.4 GO:0032423 regulation of mismatch repair(GO:0032423)
0.1 0.4 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.4 GO:1902965 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.1 0.5 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 0.2 GO:0002380 immunoglobulin secretion involved in immune response(GO:0002380)
0.1 0.4 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.2 GO:1904550 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.1 0.2 GO:1902277 negative regulation of pancreatic amylase secretion(GO:1902277)
0.1 0.1 GO:0060264 regulation of respiratory burst involved in inflammatory response(GO:0060264) negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.1 0.2 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.1 0.2 GO:1902080 regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.1 0.4 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.1 0.4 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.1 0.2 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0 0.1 GO:0003294 atrial ventricular junction remodeling(GO:0003294) regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.0 0.2 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.2 GO:1901204 regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204)
0.0 0.2 GO:0010979 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980) bile acid signaling pathway(GO:0038183)
0.0 0.3 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.2 GO:0034635 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.0 0.2 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.3 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
0.0 0.2 GO:0030210 heparin biosynthetic process(GO:0030210)
0.0 0.1 GO:0002414 immune response in mucosal-associated lymphoid tissue(GO:0002386) immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.0 0.2 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.2 GO:0035284 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.2 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.0 0.4 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.6 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.2 GO:0050758 thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758) negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.0 0.2 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.0 0.1 GO:0006203 dGTP catabolic process(GO:0006203) dATP catabolic process(GO:0046061)
0.0 0.1 GO:0030824 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
0.0 0.1 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0 0.4 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.2 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
0.0 0.1 GO:0071469 cellular response to alkaline pH(GO:0071469)
0.0 0.3 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.2 GO:0003011 involuntary skeletal muscle contraction(GO:0003011)
0.0 0.1 GO:0045054 constitutive secretory pathway(GO:0045054)
0.0 0.1 GO:0000239 pachytene(GO:0000239)
0.0 0.6 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.3 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.3 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.2 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.3 GO:0071313 cellular response to caffeine(GO:0071313)
0.0 0.8 GO:0048714 positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0 0.1 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.1 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.0 0.1 GO:1902477 defense response to bacterium, incompatible interaction(GO:0009816) regulation of defense response to bacterium, incompatible interaction(GO:1902477)
0.0 0.5 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0 0.4 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.1 GO:0052151 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.0 0.1 GO:0051935 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.0 0.1 GO:1904048 negative regulation of synaptic vesicle recycling(GO:1903422) regulation of spontaneous neurotransmitter secretion(GO:1904048)
0.0 0.3 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.2 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.0 0.8 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.1 GO:1901355 circadian regulation of translation(GO:0097167) response to rapamycin(GO:1901355)
0.0 0.1 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.1 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.0 0.2 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.1 GO:0042494 detection of bacterial lipoprotein(GO:0042494)
0.0 0.1 GO:0099578 regulation of translation at synapse, modulating synaptic transmission(GO:0099547) regulation of translation at postsynapse, modulating synaptic transmission(GO:0099578) positive regulation of intracellular transport of viral material(GO:1901254)
0.0 0.0 GO:0071349 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.0 0.6 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.1 GO:0071677 positive regulation of mononuclear cell migration(GO:0071677)
0.0 0.4 GO:0003413 chondrocyte differentiation involved in endochondral bone morphogenesis(GO:0003413)
0.0 0.3 GO:0019244 lactate biosynthetic process from pyruvate(GO:0019244)
0.0 0.2 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.1 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.0 0.6 GO:0042761 fatty acid elongation(GO:0030497) very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.1 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 0.1 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.0 0.3 GO:0042407 cristae formation(GO:0042407)
0.0 0.3 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.0 0.1 GO:0019085 early viral transcription(GO:0019085)
0.0 0.1 GO:1904925 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.0 0.1 GO:0010046 response to mycotoxin(GO:0010046)
0.0 0.1 GO:0048069 eye pigmentation(GO:0048069)
0.0 0.1 GO:2000983 regulation of ATP citrate synthase activity(GO:2000983) negative regulation of ATP citrate synthase activity(GO:2000984)
0.0 0.2 GO:1900378 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.0 0.2 GO:0032226 positive regulation of synaptic transmission, dopaminergic(GO:0032226)
0.0 0.0 GO:0060466 activation of meiosis involved in egg activation(GO:0060466)
0.0 0.9 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.2 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.2 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.4 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.1 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.1 GO:1904017 response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.0 0.1 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.0 0.2 GO:1903551 regulation of extracellular exosome assembly(GO:1903551)
0.0 0.0 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.0 0.1 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.1 GO:0050968 detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.0 0.2 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.0 0.5 GO:0060351 cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.0 0.1 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.0 0.1 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0 0.1 GO:1990166 positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184) protein localization to site of double-strand break(GO:1990166)
0.0 0.2 GO:0051014 actin filament severing(GO:0051014)
0.0 0.3 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.1 GO:0031448 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.0 GO:0097402 neuroblast migration(GO:0097402)
0.0 0.2 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.0 0.0 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.0 0.0 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0 0.1 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.3 GO:0021707 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.1 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.1 GO:0000432 carbon catabolite regulation of transcription from RNA polymerase II promoter(GO:0000429) regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) carbon catabolite activation of transcription from RNA polymerase II promoter(GO:0000436)
0.0 0.3 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.1 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.1 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.0 0.1 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.0 0.1 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.1 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.2 GO:0046512 sphingosine biosynthetic process(GO:0046512)
0.0 0.1 GO:0032725 positive regulation of granulocyte macrophage colony-stimulating factor production(GO:0032725)
0.0 0.1 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.0 0.4 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.0 0.2 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.2 GO:0097012 response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0 0.1 GO:0060179 male mating behavior(GO:0060179)
0.0 0.2 GO:0050965 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.2 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.0 0.0 GO:1902202 proteoglycan catabolic process(GO:0030167) regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0 0.3 GO:0015732 prostaglandin transport(GO:0015732)
0.0 0.1 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.0 0.1 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.1 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.1 GO:0009992 cellular water homeostasis(GO:0009992)
0.0 0.1 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.1 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.0 0.1 GO:0044268 multicellular organismal protein metabolic process(GO:0044268)
0.0 0.0 GO:0060557 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874) positive regulation of interleukin-18 production(GO:0032741) positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.0 0.2 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.0 0.2 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.0 0.1 GO:0021681 cerebellar granular layer development(GO:0021681)
0.0 0.2 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.1 GO:1901096 regulation of autophagosome maturation(GO:1901096)
0.0 0.1 GO:0046596 regulation of viral entry into host cell(GO:0046596)
0.0 0.2 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.1 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.0 GO:2000845 positive regulation of androgen secretion(GO:2000836) positive regulation of testosterone secretion(GO:2000845)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0002079 inner acrosomal membrane(GO:0002079)
0.1 0.2 GO:0034665 integrin alpha1-beta1 complex(GO:0034665)
0.1 0.2 GO:0032783 ELL-EAF complex(GO:0032783)
0.1 1.1 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 0.3 GO:0014802 terminal cisterna(GO:0014802)
0.1 0.2 GO:1990031 pinceau fiber(GO:1990031)
0.1 0.3 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.4 GO:0033010 paranodal junction(GO:0033010)
0.0 0.1 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.0 1.2 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.3 GO:0061617 MICOS complex(GO:0061617)
0.0 0.2 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0 0.2 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.0 0.3 GO:0097443 sorting endosome(GO:0097443)
0.0 0.3 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.0 1.1 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.5 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.5 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.9 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.3 GO:1990812 growth cone filopodium(GO:1990812)
0.0 0.8 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.1 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.0 0.9 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.2 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.1 GO:0035841 new growing cell tip(GO:0035841)
0.0 0.6 GO:0034385 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 0.2 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.6 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.2 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.2 GO:0071439 clathrin complex(GO:0071439)
0.0 0.5 GO:0045095 keratin filament(GO:0045095)
0.0 0.0 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.0 0.1 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.5 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.1 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.1 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0 0.2 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0031711 bradykinin receptor binding(GO:0031711)
0.2 0.5 GO:0098918 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.1 0.4 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.1 0.4 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.1 0.3 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.1 0.5 GO:0008859 exoribonuclease II activity(GO:0008859)
0.1 1.0 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.3 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1 0.4 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.1 0.4 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 0.3 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.1 0.3 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.3 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.1 1.1 GO:0035497 cAMP response element binding(GO:0035497)
0.1 0.2 GO:1902271 lithocholic acid binding(GO:1902121) D3 vitamins binding(GO:1902271)
0.1 0.2 GO:0034597 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.1 0.2 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.1 0.2 GO:0005110 frizzled-2 binding(GO:0005110)
0.1 0.3 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.1 1.4 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 0.3 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.1 0.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.2 GO:0052834 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.1 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.0 0.4 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.4 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0098782 mechanically-gated potassium channel activity(GO:0098782)
0.0 0.2 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.0 0.2 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.0 0.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.4 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.2 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.3 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.1 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.0 0.2 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.2 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.0 0.1 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.2 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.3 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.2 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 0.1 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.1 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.3 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:0033142 progesterone receptor binding(GO:0033142)
0.0 1.0 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075) gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.0 0.2 GO:0035877 death effector domain binding(GO:0035877)
0.0 0.3 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.1 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.0 0.1 GO:0034584 piRNA binding(GO:0034584)
0.0 0.4 GO:0070700 BMP receptor binding(GO:0070700)
0.0 1.2 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.0 0.3 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.1 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.0 0.1 GO:0034437 glycoprotein transporter activity(GO:0034437)
0.0 0.3 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.4 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0034618 arginine binding(GO:0034618)
0.0 0.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.0 0.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.3 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.1 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.4 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.5 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.1 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.1 GO:0071796 K6-linked polyubiquitin binding(GO:0071796)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.6 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.2 GO:0015651 quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.0 0.1 GO:0070976 calcium-independent protein kinase C activity(GO:0004699) TIR domain binding(GO:0070976)
0.0 0.1 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.1 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.1 GO:0032554 purine deoxyribonucleotide binding(GO:0032554)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 1.0 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.0 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.0 0.1 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.1 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.2 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.1 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 5.4 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.3 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.0 0.1 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.1 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.5 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.8 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.3 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.7 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.3 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.4 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.0 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.3 PID ARF 3PATHWAY Arf1 pathway
0.0 0.4 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.5 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.3 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.7 PID FGF PATHWAY FGF signaling pathway
0.0 0.4 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.9 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 1.1 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.3 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.4 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.3 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.6 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.6 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.3 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.4 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.4 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.1 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.3 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 0.2 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.5 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.3 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.3 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity