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avrg: GFI1 WT vs 36n/n vs KD

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Results for Pou5f1

Z-value: 1.35

Motif logo

Transcription factors associated with Pou5f1

Gene Symbol Gene ID Gene Info
ENSMUSG00000024406.17 POU domain, class 5, transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pou5f1mm39_v1_chr17_+_35816915_358169680.932.1e-02Click!

Activity profile of Pou5f1 motif

Sorted Z-values of Pou5f1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr13_+_23930717 2.04 ENSMUST00000099703.5
H2B clustered histone 3
chr13_-_23758370 1.84 ENSMUST00000105106.2
H2B clustered histone 7
chr3_+_96177010 1.69 ENSMUST00000051089.4
ENSMUST00000177113.2
predicted gene 42743
H2B clustered histone 18
chr3_-_96128196 1.65 ENSMUST00000090782.4
H2A clustered histone 20
chr13_+_22220000 1.57 ENSMUST00000110455.4
H2B clustered histone 12
chr13_+_21906214 1.49 ENSMUST00000224651.2
H2B clustered histone 14
chr5_+_64969679 1.47 ENSMUST00000166409.6
ENSMUST00000197879.2
Kruppel-like factor 3 (basic)
chr13_+_22017906 1.36 ENSMUST00000180288.2
H2B clustered histone 24
chr11_+_58845502 1.31 ENSMUST00000108817.5
ENSMUST00000047697.12
H2A.W histone
tripartite motif-containing 17
chr13_+_23868175 1.25 ENSMUST00000018246.6
H2B clustered histone 4
chr13_+_22227359 1.25 ENSMUST00000110452.2
H2B clustered histone 11
chr13_+_23755551 1.11 ENSMUST00000079251.8
H2B clustered histone 8
chr13_-_24118139 1.05 ENSMUST00000052776.4
H2B clustered histone 1
chr3_+_96127174 0.96 ENSMUST00000073115.5
H2A clustered histone 21
chr13_+_23935088 0.95 ENSMUST00000078369.3
H2A clustered histone 4
chr11_-_23720953 0.90 ENSMUST00000102864.5
reticuloendotheliosis oncogene
chr15_+_6552270 0.90 ENSMUST00000226412.2
FYN binding protein
chr13_-_54836059 0.89 ENSMUST00000122935.2
ENSMUST00000128257.8
ring finger protein 44
chr8_-_123405392 0.83 ENSMUST00000134045.2
CBFA2/RUNX1 translocation partner 3
chr6_-_70237939 0.82 ENSMUST00000103386.3
immunoglobulin kappa variable 6-23
chr14_-_67106037 0.82 ENSMUST00000022629.9
dihydropyrimidinase-like 2
chr16_-_4698148 0.78 ENSMUST00000037843.7
UBA-like domain containing 1
chr12_-_99378855 0.74 ENSMUST00000177269.2
forkhead box N3
chr5_+_129661233 0.73 ENSMUST00000031390.10
matrix metallopeptidase 17
chr13_-_23867924 0.71 ENSMUST00000171127.4
H2A clustered histone 6
chr6_+_136495818 0.70 ENSMUST00000186577.7
activating transcription factor 7 interacting protein
chr4_+_119671688 0.69 ENSMUST00000106307.9
human immunodeficiency virus type I enhancer binding protein 3
chr8_-_116434517 0.69 ENSMUST00000109104.2
avian musculoaponeurotic fibrosarcoma oncogene homolog
chr9_+_106099797 0.69 ENSMUST00000062241.11
toll-like receptor 9
chr8_+_108669276 0.69 ENSMUST00000220518.2
zinc finger homeobox 3
chr15_+_6609322 0.68 ENSMUST00000090461.12
FYN binding protein
chr8_+_91635192 0.68 ENSMUST00000211403.2
chromodomain helicase DNA binding protein 9
chr9_-_51076724 0.67 ENSMUST00000210433.2
predicted gene, 32742
chr13_-_22219738 0.66 ENSMUST00000091742.6
H2A clustered histone 12
chr13_-_23755374 0.64 ENSMUST00000102969.6
H2A clustered histone 8
chr2_+_28082943 0.62 ENSMUST00000113920.8
olfactomedin 1
chr13_+_38009981 0.62 ENSMUST00000110238.10
ras responsive element binding protein 1
chr13_-_54835996 0.61 ENSMUST00000150806.8
ENSMUST00000125927.8
ring finger protein 44
chr2_-_18053158 0.58 ENSMUST00000066885.6
SKI/DACH domain containing 1
chr3_-_58792633 0.57 ENSMUST00000055636.13
ENSMUST00000072551.7
ENSMUST00000051408.8
clarin 1
chr7_-_15781838 0.57 ENSMUST00000210781.2
BRD4 interacting chromatin remodeling complex associated protein
chr13_-_54835878 0.55 ENSMUST00000125871.8
ring finger protein 44
chr2_+_71884943 0.53 ENSMUST00000028525.6
Rap guanine nucleotide exchange factor (GEF) 4
chr14_+_71127540 0.53 ENSMUST00000022699.10
glial cell line derived neurotrophic factor family receptor alpha 2
chr16_-_92494203 0.53 ENSMUST00000113956.10
runt related transcription factor 1
chr2_+_28083105 0.52 ENSMUST00000100244.10
olfactomedin 1
chr13_-_95661726 0.51 ENSMUST00000022185.10
coagulation factor II (thrombin) receptor-like 1
chr17_-_35383867 0.51 ENSMUST00000025253.12
proline-rich coiled-coil 2A
chr2_-_18053595 0.51 ENSMUST00000142856.2
SKI/DACH domain containing 1
chr13_-_22017677 0.51 ENSMUST00000081342.7
H2A clustered histone 24
chr2_-_45000389 0.50 ENSMUST00000201804.4
ENSMUST00000028229.13
ENSMUST00000202187.4
ENSMUST00000153561.6
ENSMUST00000201490.2
zinc finger E-box binding homeobox 2
chr18_+_69726654 0.50 ENSMUST00000200921.4
transcription factor 4
chr6_+_136931519 0.49 ENSMUST00000137768.2
phosphodiesterase 6H, cGMP-specific, cone, gamma
chr3_+_45332831 0.47 ENSMUST00000193252.2
ENSMUST00000171554.8
ENSMUST00000166126.7
ENSMUST00000170695.4
protocadherin 10
chr12_+_71095112 0.47 ENSMUST00000135709.2
AT rich interactive domain 4A (RBP1-like)
chr7_+_79675727 0.45 ENSMUST00000049680.10
zinc finger protein 710
chr13_+_41040657 0.44 ENSMUST00000069958.15
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr8_-_85500010 0.44 ENSMUST00000109764.8
nuclear factor I/X
chr13_-_22227114 0.44 ENSMUST00000091741.6
H2A clustered histone 11
chr1_+_143516402 0.43 ENSMUST00000038252.4
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr19_+_13594739 0.43 ENSMUST00000217061.3
ENSMUST00000209005.4
ENSMUST00000208347.3
olfactory receptor 1487
chr7_-_78228116 0.42 ENSMUST00000206268.2
ENSMUST00000039431.14
neurotrophic tyrosine kinase, receptor, type 3
chr19_+_13608985 0.42 ENSMUST00000217182.3
olfactory receptor 1489
chr11_+_115272732 0.41 ENSMUST00000053288.6
cerebellar degeneration-related protein 2-like
chr12_-_114252202 0.41 ENSMUST00000195124.6
ENSMUST00000103481.3
immunoglobulin heavy variable 3-6
chrX_-_16777913 0.40 ENSMUST00000040134.8
Norrie disease (pseudoglioma) (human)
chr10_+_7708178 0.40 ENSMUST00000039484.6
zinc finger CCCH type containing 12D
chr13_+_41071077 0.40 ENSMUST00000067778.8
ENSMUST00000225759.2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr5_+_75316552 0.39 ENSMUST00000168162.5
platelet derived growth factor receptor, alpha polypeptide
chr6_+_136495784 0.39 ENSMUST00000032335.13
ENSMUST00000185724.7
activating transcription factor 7 interacting protein
chr2_-_59778560 0.39 ENSMUST00000153136.2
bromodomain adjacent to zinc finger domain, 2B
chrX_+_7744535 0.39 ENSMUST00000033495.15
proviral integration site 2
chr1_-_87322443 0.38 ENSMUST00000113212.4
potassium inwardly-rectifying channel, subfamily J, member 13
chr13_+_23758555 0.38 ENSMUST00000090776.7
H2A clustered histone 7
chr10_-_12490424 0.38 ENSMUST00000217994.2
utrophin
chr19_-_40982576 0.37 ENSMUST00000117695.8
B cell linker
chr13_+_5911481 0.37 ENSMUST00000000080.8
Kruppel-like factor 6
chr13_-_54836077 0.37 ENSMUST00000150626.2
ENSMUST00000134177.8
ring finger protein 44
chr11_+_44508137 0.37 ENSMUST00000109268.2
ENSMUST00000101326.10
ENSMUST00000081265.12
early B cell factor 1
chr1_-_143879738 0.37 ENSMUST00000153527.3
regulator of G-protein signaling 2
chr13_-_54835508 0.36 ENSMUST00000177950.8
ENSMUST00000146931.8
ring finger protein 44
chrX_+_80114242 0.36 ENSMUST00000171953.8
ENSMUST00000026760.3
transmembrane protein 47
chr9_+_86625694 0.35 ENSMUST00000179574.2
ENSMUST00000036426.13
protease, serine 35
chr4_+_97660971 0.35 ENSMUST00000152023.8
nuclear factor I/A
chr11_-_98666159 0.34 ENSMUST00000064941.7
nuclear receptor subfamily 1, group D, member 1
chr4_-_128699838 0.33 ENSMUST00000106072.9
ENSMUST00000170934.3
zinc finger protein 362
chr11_-_115968745 0.33 ENSMUST00000156545.2
ENSMUST00000075036.9
ENSMUST00000106451.8
unc-13 homolog D
chr4_-_24800890 0.33 ENSMUST00000108214.9
kelch-like 32
chr6_+_68402550 0.33 ENSMUST00000103323.3
immunoglobulin kappa variable 16-104
chr5_+_42225303 0.31 ENSMUST00000087332.5
predicted gene 16223
chr7_-_45546081 0.31 ENSMUST00000120299.4
ENSMUST00000039049.16
synaptogyrin 4
chr7_+_110372860 0.31 ENSMUST00000143786.2
adenosine monophosphate deaminase 3
chrX_-_139443926 0.31 ENSMUST00000055738.12
TSC22 domain family, member 3
chr7_+_79676095 0.31 ENSMUST00000206039.2
zinc finger protein 710
chr11_+_74721733 0.30 ENSMUST00000000291.9
max binding protein
chr18_+_69726431 0.30 ENSMUST00000201091.4
ENSMUST00000201037.4
ENSMUST00000114977.5
transcription factor 4
chr1_+_128069677 0.29 ENSMUST00000187023.7
R3H domain containing 1
chr5_+_21748523 0.29 ENSMUST00000035651.6
leucine rich repeat containing 17
chr4_+_105014536 0.28 ENSMUST00000064139.8
phospholipid phosphatase 3
chr13_+_83672965 0.28 ENSMUST00000199432.5
ENSMUST00000198069.5
ENSMUST00000197681.5
ENSMUST00000197722.5
ENSMUST00000197938.5
myocyte enhancer factor 2C
chr5_+_104447037 0.27 ENSMUST00000031246.9
integrin binding sialoprotein
chr4_-_62278761 0.27 ENSMUST00000107461.2
ENSMUST00000084528.10
FK506 binding protein 15
chr10_+_79763164 0.27 ENSMUST00000105376.2
AT rich interactive domain 3A (BRIGHT-like)
chr8_+_71207326 0.27 ENSMUST00000110093.9
ENSMUST00000143118.3
ENSMUST00000034301.12
ENSMUST00000110090.8
RAB3A, member RAS oncogene family
chr6_-_70412460 0.27 ENSMUST00000103394.2
immunoglobulin kappa variable 6-14
chr7_+_44667377 0.26 ENSMUST00000044111.10
related RAS viral (r-ras) oncogene
chr7_+_24981604 0.26 ENSMUST00000163320.8
ENSMUST00000005578.13
capicua transcriptional repressor
chr5_-_142880987 0.26 ENSMUST00000035985.8
F-box and leucine-rich repeat protein 18
chr17_+_47451868 0.26 ENSMUST00000190080.9
transcriptional regulating factor 1
chr16_+_91526169 0.25 ENSMUST00000114001.8
ENSMUST00000113999.8
ENSMUST00000064797.12
ENSMUST00000114002.9
ENSMUST00000095909.10
ENSMUST00000056482.14
ENSMUST00000113996.8
intersectin 1 (SH3 domain protein 1A)
chr13_+_102830029 0.24 ENSMUST00000022124.10
ENSMUST00000171267.2
ENSMUST00000167144.2
ENSMUST00000170878.2
CD180 antigen
chr12_-_56583582 0.24 ENSMUST00000001536.9
NK2 homeobox 1
chr2_-_160950936 0.24 ENSMUST00000039782.14
ENSMUST00000134178.8
chromodomain helicase DNA binding protein 6
chr6_+_68247469 0.24 ENSMUST00000103321.3
immunoglobulin kappa variable 1-110
chr6_+_68026941 0.23 ENSMUST00000103316.2
immunoglobulin kappa chain variable 9-120
chr9_-_102231884 0.22 ENSMUST00000035129.14
ENSMUST00000085169.12
ENSMUST00000149800.3
Eph receptor B1
chr6_+_92069376 0.22 ENSMUST00000113463.8
nuclear receptor subfamily 2, group C, member 2
chr8_+_23464860 0.22 ENSMUST00000110688.9
ENSMUST00000121802.9
ankyrin 1, erythroid
chr5_+_138083345 0.22 ENSMUST00000019660.11
ENSMUST00000066617.12
ENSMUST00000110963.8
zinc finger with KRAB and SCAN domains 1
chr8_+_66838927 0.22 ENSMUST00000039540.12
ENSMUST00000110253.3
membrane associated ring-CH-type finger 1
chr2_-_45001141 0.22 ENSMUST00000201969.4
ENSMUST00000201623.4
zinc finger E-box binding homeobox 2
chr3_-_144525255 0.22 ENSMUST00000029929.12
chloride channel accessory 3A2
chr2_+_90927053 0.22 ENSMUST00000132741.3
spleen focus forming virus (SFFV) proviral integration oncogene
chr12_-_114752425 0.21 ENSMUST00000103510.2
immunoglobulin heavy variable 1-26
chr8_+_121215155 0.21 ENSMUST00000034279.16
genetic suppressor element 1, coiled-coil protein
chr2_+_121120070 0.21 ENSMUST00000094639.10
microtubule-associated protein 1 A
chr10_-_127456791 0.20 ENSMUST00000118455.2
ENSMUST00000121829.8
low density lipoprotein receptor-related protein 1
chr8_+_23548541 0.20 ENSMUST00000173248.8
ankyrin 1, erythroid
chr4_-_152561896 0.20 ENSMUST00000238738.2
ENSMUST00000162017.3
ENSMUST00000030768.10
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr2_-_32977182 0.20 ENSMUST00000102810.10
GTPase activating RANGAP domain-like 3
chr2_-_111908072 0.20 ENSMUST00000213577.2
ENSMUST00000216071.2
olfactory receptor 1313
chr18_+_69726055 0.20 ENSMUST00000114978.9
transcription factor 4
chr1_-_64160557 0.20 ENSMUST00000055001.10
ENSMUST00000114086.8
Kruppel-like factor 7 (ubiquitous)
chr2_-_45007407 0.20 ENSMUST00000176438.9
zinc finger E-box binding homeobox 2
chr6_-_70292451 0.19 ENSMUST00000103387.3
immunoglobulin kappa variable 8-21
chr1_-_163141230 0.18 ENSMUST00000174397.3
ENSMUST00000075805.13
paired related homeobox 1
chr17_+_41121979 0.18 ENSMUST00000024721.8
ENSMUST00000233740.2
Rhesus blood group-associated A glycoprotein
chr6_+_68233361 0.18 ENSMUST00000103320.3
immunoglobulin kappa variable 14-111
chr5_+_76988444 0.18 ENSMUST00000120639.9
ENSMUST00000163347.8
ENSMUST00000121851.2
capping protein inhibiting regulator of actin
chr10_-_8761777 0.18 ENSMUST00000015449.6
SAM and SH3 domain containing 1
chr17_-_24752683 0.18 ENSMUST00000061764.14
RAB26, member RAS oncogene family
chr17_-_36220518 0.18 ENSMUST00000141132.2
alpha tubulin acetyltransferase 1
chr6_+_70675416 0.18 ENSMUST00000103403.3
immunoglobulin kappa variable 3-2
chr10_+_79762858 0.18 ENSMUST00000019708.12
ENSMUST00000105377.8
AT rich interactive domain 3A (BRIGHT-like)
chr6_+_122684448 0.18 ENSMUST00000112581.8
ENSMUST00000112580.8
ENSMUST00000012540.5
Nanog homeobox
chr7_-_28071919 0.18 ENSMUST00000119990.8
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr3_-_84128160 0.17 ENSMUST00000154152.2
ENSMUST00000107693.9
ENSMUST00000107695.9
tripartite motif-containing 2
chr4_-_62278673 0.17 ENSMUST00000084527.10
ENSMUST00000098033.10
FK506 binding protein 15
chr6_+_68279392 0.17 ENSMUST00000103322.3
immunoglobulin kappa variable 2-109
chr6_+_108190163 0.17 ENSMUST00000203615.3
inositol 1,4,5-trisphosphate receptor 1
chr15_+_12824925 0.17 ENSMUST00000090292.13
drosha, ribonuclease type III
chr1_-_66856695 0.17 ENSMUST00000068168.10
ENSMUST00000113987.2
KAT8 regulatory NSL complex subunit 1-like
chr2_+_51928017 0.17 ENSMUST00000065927.6
tumor necrosis factor alpha induced protein 6
chr5_+_105879914 0.17 ENSMUST00000154807.2
leucine rich repeat containing 8D
chr12_-_115876396 0.17 ENSMUST00000103547.2
immunoglobulin heavy variable 1-80
chr2_-_26393826 0.16 ENSMUST00000028288.5
notch 1
chr9_-_103980200 0.16 ENSMUST00000188000.2
atypical chemokine receptor 4
chr14_-_103220066 0.16 ENSMUST00000184744.2
potassium channel tetramerisation domain containing 12
chr12_-_113552322 0.16 ENSMUST00000103443.3
immunoglobulin heavy variable 2-2
chr2_-_25982160 0.16 ENSMUST00000114159.9
nucleus accumbens associated 2, BEN and BTB (POZ) domain containing
chr7_-_44702269 0.15 ENSMUST00000057293.8
proline rich 12
chr13_-_108026590 0.15 ENSMUST00000225822.4
ENSMUST00000225197.3
zinc finger SWIM-type containing 6
chr8_-_34237752 0.15 ENSMUST00000179364.3
small integral membrane protein 18
chr6_-_70383976 0.15 ENSMUST00000103393.2
immunoglobulin kappa variable 6-15
chr6_-_70121150 0.15 ENSMUST00000197525.2
immunoglobulin kappa variable 8-28
chrX_+_165127688 0.15 ENSMUST00000112223.8
ENSMUST00000112224.8
ENSMUST00000112229.9
ENSMUST00000112228.8
ENSMUST00000112227.9
ENSMUST00000112226.3
glycoprotein m6b
chr13_+_14238361 0.15 ENSMUST00000129488.8
ENSMUST00000110536.8
ENSMUST00000110534.8
ENSMUST00000039538.15
ENSMUST00000110533.2
AT rich interactive domain 4B (RBP1-like)
chr6_+_108190050 0.15 ENSMUST00000032192.9
inositol 1,4,5-trisphosphate receptor 1
chrX_+_93278203 0.14 ENSMUST00000153900.8
kelch-like 15
chr11_-_48708159 0.14 ENSMUST00000047145.14
tripartite motif-containing 41
chr14_+_20398230 0.14 ENSMUST00000224930.2
ENSMUST00000224110.2
ENSMUST00000225942.2
ENSMUST00000051915.7
ENSMUST00000090499.13
ENSMUST00000224721.2
ENSMUST00000090503.12
ENSMUST00000225991.2
ENSMUST00000037698.13
family with sequence similarity 149, member B
chr12_+_52746158 0.14 ENSMUST00000095737.5
A kinase (PRKA) anchor protein 6
chr7_+_63835285 0.14 ENSMUST00000206263.2
ENSMUST00000206107.2
ENSMUST00000205731.2
ENSMUST00000206706.2
ENSMUST00000205690.2
transient receptor potential cation channel, subfamily M, member 1
chr16_-_16962279 0.14 ENSMUST00000232033.2
ENSMUST00000231597.2
ENSMUST00000232540.2
coiled-coil domain containing 116
chr2_-_35995283 0.14 ENSMUST00000112960.8
ENSMUST00000112967.12
ENSMUST00000112963.8
LIM homeobox protein 6
chr5_+_111565129 0.13 ENSMUST00000094463.5
meningioma 1
chr6_+_70648743 0.13 ENSMUST00000103401.3
immunoglobulin kappa variable 3-4
chr7_+_110373447 0.13 ENSMUST00000147587.2
adenosine monophosphate deaminase 3
chr6_+_68414401 0.13 ENSMUST00000103324.3
immunoglobulin kappa chain variable 15-103
chr7_-_28072022 0.13 ENSMUST00000144700.8
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr10_+_128542120 0.13 ENSMUST00000054125.9
premelanosome protein
chr1_-_91386976 0.13 ENSMUST00000069620.10
period circadian clock 2
chr1_-_163141278 0.12 ENSMUST00000027878.14
paired related homeobox 1
chr2_+_30485048 0.12 ENSMUST00000102853.4
CSA-conditional, T cell activation-dependent protein
chr6_-_55658242 0.12 ENSMUST00000044767.10
neurogenic differentiation 6
chr11_-_3454766 0.12 ENSMUST00000044507.12
inositol polyphosphate 5-phosphatase J
chr16_+_10306075 0.12 ENSMUST00000023147.8
class II transactivator
chr4_+_136150835 0.12 ENSMUST00000088677.5
ENSMUST00000121571.8
ENSMUST00000117699.2
5-hydroxytryptamine (serotonin) receptor 1D
chr12_-_113625906 0.12 ENSMUST00000103448.3
immunoglobulin heavy variable 5-9
chr12_-_114878652 0.12 ENSMUST00000103515.2
immunoglobulin heavy variable 1-39
chr13_+_102830104 0.12 ENSMUST00000172138.2
CD180 antigen
chr2_+_57128309 0.11 ENSMUST00000112618.9
ENSMUST00000028167.3
glycerol phosphate dehydrogenase 2, mitochondrial
chr8_+_71069476 0.11 ENSMUST00000052437.6
leucine rich repeat containing 25
chr15_+_57558048 0.11 ENSMUST00000096430.11
zinc fingers and homeoboxes 2
chr14_-_39194782 0.11 ENSMUST00000168810.9
ENSMUST00000173780.2
ENSMUST00000166968.9
neuregulin 3
chr9_+_123901979 0.11 ENSMUST00000171719.8
chemokine (C-C motif) receptor 2
chr7_+_18962301 0.11 ENSMUST00000161711.2
optic atrophy 3
chr4_-_63965161 0.11 ENSMUST00000107377.10
tenascin C
chr1_-_143879877 0.11 ENSMUST00000127206.8
regulator of G-protein signaling 2
chr12_-_114443071 0.11 ENSMUST00000103492.2
immunoglobulin heavy variable 10-1

Network of associatons between targets according to the STRING database.

First level regulatory network of Pou5f1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0032741 positive regulation of interleukin-18 production(GO:0032741)
0.2 0.5 GO:1900135 positive regulation of eosinophil degranulation(GO:0043311) regulation of neutrophil mediated cytotoxicity(GO:0070948) regulation of neutrophil mediated killing of symbiont cell(GO:0070949) positive regulation of renin secretion into blood stream(GO:1900135) positive regulation of eosinophil activation(GO:1902568)
0.1 0.7 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.5 GO:2000872 positive regulation of progesterone secretion(GO:2000872)
0.1 0.9 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.8 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 0.5 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
0.1 0.9 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.1 0.7 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1 0.4 GO:0048691 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
0.1 0.4 GO:0072275 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.1 1.1 GO:0023041 neuronal signal transduction(GO:0023041)
0.1 0.4 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.1 0.2 GO:0021759 globus pallidus development(GO:0021759)
0.1 0.1 GO:0043309 regulation of eosinophil degranulation(GO:0043309)
0.1 0.8 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.1 0.5 GO:0010519 negative regulation of phospholipase activity(GO:0010519)
0.1 0.3 GO:0070859 positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.1 0.4 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 0.6 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.1 0.5 GO:0002432 granuloma formation(GO:0002432)
0.1 0.2 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.1 0.2 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.1 0.3 GO:0044330 canonical Wnt signaling pathway involved in positive regulation of wound healing(GO:0044330)
0.1 0.2 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.1 0.4 GO:0007527 adult somatic muscle development(GO:0007527)
0.1 0.3 GO:0050975 sensory perception of touch(GO:0050975)
0.1 0.2 GO:1900477 negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter(GO:1900477)
0.1 0.4 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.2 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.0 0.4 GO:0032264 IMP salvage(GO:0032264)
0.0 0.2 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 0.1 GO:0031554 regulation of DNA-templated transcription, termination(GO:0031554)
0.0 0.5 GO:0050957 equilibrioception(GO:0050957)
0.0 0.7 GO:0042756 drinking behavior(GO:0042756)
0.0 0.2 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.3 GO:0050882 epithelial fluid transport(GO:0042045) voluntary musculoskeletal movement(GO:0050882)
0.0 0.3 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.1 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.0 0.4 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0 0.3 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.1 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.0 0.7 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.0 0.2 GO:2001015 negative regulation of skeletal muscle cell differentiation(GO:2001015)
0.0 0.7 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.1 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.2 GO:0048539 bone marrow development(GO:0048539)
0.0 0.1 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.5 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.0 0.8 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.0 0.1 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.0 0.4 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0 0.4 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.1 GO:0060596 mammary placode formation(GO:0060596)
0.0 0.1 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:0070495 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 1.6 GO:0045576 mast cell activation(GO:0045576)
0.0 0.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 1.3 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.1 GO:0045659 negative regulation of neutrophil differentiation(GO:0045659)
0.0 0.1 GO:0044727 DNA demethylation of male pronucleus(GO:0044727)
0.0 0.2 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.1 GO:0048023 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.0 0.1 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.0 0.5 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0 0.1 GO:0045348 positive regulation of MHC class II biosynthetic process(GO:0045348)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.2 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.1 GO:0051013 microtubule severing(GO:0051013)
0.0 0.1 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.0 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0036019 endolysosome(GO:0036019)
0.1 0.5 GO:0044316 cone cell pedicle(GO:0044316)
0.1 0.3 GO:1903095 microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)
0.1 0.3 GO:0031088 platelet dense granule membrane(GO:0031088)
0.1 0.9 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.2 GO:1990031 pinceau fiber(GO:1990031)
0.1 0.5 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.1 GO:0035841 new growing cell tip(GO:0035841)
0.0 0.5 GO:0031143 pseudopodium(GO:0031143)
0.0 1.1 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.4 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.6 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.1 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.2 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.4 GO:0070938 contractile ring(GO:0070938)
0.0 0.1 GO:0033269 internode region of axon(GO:0033269)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 0.4 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1 0.5 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.1 0.5 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 0.7 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 0.3 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1 0.4 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.1 0.2 GO:0019002 GMP binding(GO:0019002)
0.1 0.3 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.1 GO:0035717 chemokine (C-C motif) ligand 7 binding(GO:0035717)
0.0 0.4 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0 0.4 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004) neurotrophin receptor activity(GO:0005030)
0.0 0.1 GO:0016901 glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.2 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.3 GO:0043426 MRF binding(GO:0043426)
0.0 1.9 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.4 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.1 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.0 0.5 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.1 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.6 GO:0030553 cGMP binding(GO:0030553)
0.0 0.3 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.2 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0 0.4 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 1.0 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.5 GO:0030552 cAMP binding(GO:0030552)
0.0 0.5 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.4 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.5 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.4 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.5 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.6 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.7 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.4 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.7 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.3 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.8 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.7 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.3 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.1 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.4 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL