ISMARA results: Prdm4

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avrg: GFI1 WT vs 36n/n vs KD

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Results for Prdm4

Z-value: 0.67

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Transcription factors associated with Prdm4

Gene Symbol	Gene ID	Gene Info
Prdm4 Ensembl NCBI MGI UniProt	ENSMUSG00000035529.11	PR domain containing 4

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Prdm4	mm39_v1_chr10_-_85752932_85753002	0.76	1.4e-01	Click!

Activity profile of Prdm4 motif

Sorted Z-values of Prdm4 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr13_-_23735822 Show fit	1.17	ENSMUST00000102971.2	H4c6 Ensembl NCBI MGI UniProt Show fit	H4 clustered histone 6
chr5_-_142803135 Show fit	0.82	ENSMUST00000198181.2	Tnrc18 Ensembl NCBI MGI UniProt Show fit	trinucleotide repeat containing 18
chr12_+_113115632 Show fit	0.74	ENSMUST00000006523.12 ENSMUST00000200553.2	Crip1 Ensembl NCBI MGI UniProt Show fit	cysteine-rich protein 1 (intestinal)
chr19_-_4213347 Show fit	0.38	ENSMUST00000025749.15	Rps6kb2 Ensembl NCBI MGI UniProt Show fit	ribosomal protein S6 kinase, polypeptide 2
chr10_+_126814542 Show fit	0.37	ENSMUST00000105256.10	Ctdsp2 Ensembl NCBI MGI UniProt Show fit	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr5_-_142803405 Show fit	0.17	ENSMUST00000151477.8	Tnrc18 Ensembl NCBI MGI UniProt Show fit	trinucleotide repeat containing 18
chr2_+_97298002 Show fit	0.09	ENSMUST00000059049.8	Lrrc4c Ensembl NCBI MGI UniProt Show fit	leucine rich repeat containing 4C
chr7_-_30443106 Show fit	0.09	ENSMUST00000182634.8	Gapdhs Ensembl NCBI MGI UniProt Show fit	glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr15_-_99372575 Show fit	0.04	ENSMUST00000040313.6	Bcdin3d Ensembl NCBI MGI UniProt Show fit	BCDIN3 domain containing
chr19_-_12080698 Show fit	0.01	ENSMUST00000216069.2 ENSMUST00000215374.2	Olfr1427 Ensembl NCBI MGI UniProt Show fit	olfactory receptor 1427
chrX_+_135828069 Show fit	0.01	ENSMUST00000059808.5	H2bw2 Ensembl NCBI MGI UniProt Show fit	H2B.W histone 2
chrX_+_21581135 Show fit	0.01	ENSMUST00000033414.8	Slc6a14 Ensembl NCBI MGI UniProt Show fit	solute carrier family 6 (neurotransmitter transporter), member 14
chr11_-_70423765 Show fit	0.01	ENSMUST00000209971.2	Gm40193 Ensembl NCBI MGI UniProt Show fit	predicted gene, 40193
chr11_-_43727071 Show fit	0.00	ENSMUST00000167574.2	Adra1b Ensembl NCBI MGI UniProt Show fit	adrenergic receptor, alpha 1b
chr15_-_98093423 Show fit	0.00	ENSMUST00000165379.8	Olfr288 Ensembl NCBI MGI UniProt Show fit	olfactory receptor 288
chr8_+_123920682 Show fit	0.00	ENSMUST00000212409.2	Dpep1 Ensembl NCBI MGI UniProt Show fit	dipeptidase 1
chr7_+_43616163 Show fit	0.00	ENSMUST00000078835.3	Klk1b1 Ensembl NCBI MGI UniProt Show fit	kallikrein 1-related peptidase b1
chr9_+_106503781 Show fit	0.00	ENSMUST00000171091.4	Iqcf6 Ensembl NCBI MGI UniProt Show fit	IQ motif containing F6

Network of associatons between targets according to the STRING database.

First level regulatory network of Prdm4

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.0	GO:0031507	heterochromatin assembly(GO:0031507)
0.0	0.7	GO:0071493	cellular response to UV-B(GO:0071493)
0.0	0.3	GO:0045948	positive regulation of translational initiation(GO:0045948)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.0	GO:0005677	chromatin silencing complex(GO:0005677)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0004711	ribosomal protein S6 kinase activity(GO:0004711)
0.0	0.7	GO:0008301	DNA binding, bending(GO:0008301)
0.0	0.3	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.1	GO:0043891	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)