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avrg: GFI1 WT vs 36n/n vs KD

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Results for Prrx1_Isx_Prrxl1

Z-value: 1.63

Motif logo

Transcription factors associated with Prrx1_Isx_Prrxl1

Gene Symbol Gene ID Gene Info
ENSMUSG00000026586.17 paired related homeobox 1
ENSMUSG00000031621.10 intestine specific homeobox
ENSMUSG00000041730.15 paired related homeobox protein-like 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Prrxl1mm39_v1_chr14_+_32321341_32321498-0.875.5e-02Click!
Prrx1mm39_v1_chr1_-_163141230_163141246-0.791.1e-01Click!
Isxmm39_v1_chr8_+_75599801_75599855-0.276.6e-01Click!

Activity profile of Prrx1_Isx_Prrxl1 motif

Sorted Z-values of Prrx1_Isx_Prrxl1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr18_+_60907698 2.01 ENSMUST00000118551.8
ribosomal protein S14
chr8_+_106786190 1.82 ENSMUST00000109308.3
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3
chr6_+_40619913 1.62 ENSMUST00000238599.2
maltase-glucoamylase
chr18_+_60907668 1.61 ENSMUST00000025511.11
ribosomal protein S14
chr4_-_87724533 1.57 ENSMUST00000126353.8
ENSMUST00000149357.8
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 3
chr6_-_34294377 1.41 ENSMUST00000154655.2
ENSMUST00000102980.11
aldo-keto reductase family 1, member B3 (aldose reductase)
chr18_-_43610829 1.36 ENSMUST00000057110.11
eukaryotic translation initiation factor 3, subunit J2
chr16_+_49620883 1.35 ENSMUST00000229640.2
CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
chr1_-_24044688 1.24 ENSMUST00000027338.4
succinate dehydrogenase complex assembly factor 4
chr4_-_87724512 1.19 ENSMUST00000148059.2
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 3
chr15_+_65682066 1.17 ENSMUST00000211878.2
EFR3 homolog A
chrX_+_37689503 0.97 ENSMUST00000000365.3
malignant T cell amplified sequence 1
chr3_+_159545309 0.93 ENSMUST00000068952.10
ENSMUST00000198878.2
wntless WNT ligand secretion mediator
chr3_+_32490300 0.91 ENSMUST00000029201.14
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
chr10_+_82695013 0.90 ENSMUST00000020484.9
ENSMUST00000219962.3
thioredoxin reductase 1
chr15_+_100202061 0.78 ENSMUST00000229574.2
ENSMUST00000229217.2
methyltransferase like 7A1
chr12_-_79237722 0.78 ENSMUST00000085254.7
retinol dehydrogenase 11
chr13_-_4659120 0.76 ENSMUST00000091848.7
ENSMUST00000110691.10
aldo-keto reductase family 1, member E1
chr15_+_100202079 0.74 ENSMUST00000230252.2
ENSMUST00000231166.2
methyltransferase like 7A1
chr18_+_3382968 0.74 ENSMUST00000025073.12
cullin 2
chr11_-_117764258 0.70 ENSMUST00000033230.8
threonine aldolase 1
chr8_-_58106057 0.70 ENSMUST00000034021.12
polypeptide N-acetylgalactosaminyltransferase 7
chr15_+_100202021 0.69 ENSMUST00000230472.2
methyltransferase like 7A1
chr12_-_75678092 0.69 ENSMUST00000238938.2
ribosomal protein, large P2, pseudogene 1
chr7_+_99808452 0.68 ENSMUST00000032967.4
lipoyl(octanoyl) transferase 2 (putative)
chr19_-_24178000 0.68 ENSMUST00000233658.3
tight junction protein 2
chr5_+_52940391 0.65 ENSMUST00000031077.13
ENSMUST00000113904.9
ENSMUST00000199840.2
zinc finger, CCHC domain containing 4
chr17_+_64203017 0.64 ENSMUST00000000129.14
fer (fms/fps related) protein kinase
chr10_+_99099084 0.62 ENSMUST00000020118.5
ENSMUST00000220291.2
dual specificity phosphatase 6
chr14_-_104760051 0.62 ENSMUST00000022716.4
ENSMUST00000228448.2
ENSMUST00000227640.2
ORC ubiquitin ligase 1
chr12_-_73093953 0.61 ENSMUST00000050029.8
sine oculis-related homeobox 1
chr8_-_58106027 0.59 ENSMUST00000110316.3
polypeptide N-acetylgalactosaminyltransferase 7
chr9_+_119170486 0.58 ENSMUST00000175743.8
ENSMUST00000176397.8
acetyl-Coenzyme A acyltransferase 1A
chr6_+_86342622 0.57 ENSMUST00000071492.9
family with sequence similarity 136, member A
chr17_-_36353582 0.57 ENSMUST00000058801.15
ENSMUST00000080015.12
ENSMUST00000077960.7
histocompatibility 2, T region locus 22
chr11_-_17903861 0.53 ENSMUST00000076661.7
Ewing tumor-associated antigen 1
chr13_+_96524802 0.53 ENSMUST00000099295.6
POC5 centriolar protein
chr14_-_14255736 0.50 ENSMUST00000170111.3
potassium channel tetramerisation domain containing 6
chr8_+_22682816 0.49 ENSMUST00000033866.9
vacuolar protein sorting 36
chr3_+_96552895 0.48 ENSMUST00000119365.8
ENSMUST00000029744.6
integrin, alpha 10
chr7_+_102090892 0.48 ENSMUST00000033283.10
ribonucleotide reductase M1
chr12_-_84664001 0.47 ENSMUST00000221070.2
ENSMUST00000021666.6
ENSMUST00000223107.2
ATP-binding cassette, sub-family D (ALD), member 4
chr9_-_96774719 0.47 ENSMUST00000154146.8
2-phosphoxylose phosphatase 1
chrM_+_7758 0.45 ENSMUST00000082407.1
mitochondrially encoded ATP synthase 8
chr11_-_74615496 0.45 ENSMUST00000021091.15
platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
chr9_+_19533591 0.44 ENSMUST00000215372.2
zinc finger protein 317
chr7_+_99808526 0.44 ENSMUST00000207825.2
lipoyl(octanoyl) transferase 2 (putative)
chr14_-_36857202 0.44 ENSMUST00000165649.4
ENSMUST00000224769.2
growth hormone inducible transmembrane protein
chr1_-_160898181 0.44 ENSMUST00000035430.4
aspartyl-tRNA synthetase 2 (mitochondrial)
chr3_+_32490525 0.44 ENSMUST00000108242.2
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
chrM_+_7779 0.43 ENSMUST00000082408.1
mitochondrially encoded ATP synthase 6
chr14_+_32507920 0.43 ENSMUST00000039191.8
ENSMUST00000227060.2
ENSMUST00000228481.2
transmembrane protein 273
chr10_+_82695055 0.42 ENSMUST00000218694.2
thioredoxin reductase 1
chr7_+_126575781 0.42 ENSMUST00000206450.2
ENSMUST00000205830.2
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)
chr16_+_38167352 0.40 ENSMUST00000050273.9
ENSMUST00000120495.2
ENSMUST00000119704.2
cytochrome c oxidase assembly protein 17, copper chaperone
predicted gene 21987
chr12_-_80690573 0.40 ENSMUST00000166931.2
ENSMUST00000218364.2
ERH mRNA splicing and mitosis factor
chr9_+_118307412 0.40 ENSMUST00000035020.15
eomesodermin
chr6_-_86710250 0.39 ENSMUST00000001185.14
germ cell-less, spermatogenesis associated 1
chr7_-_24423715 0.39 ENSMUST00000081657.6
Ly6/PLAUR domain containing 11
chr17_+_46807637 0.39 ENSMUST00000046497.8
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr11_+_58062467 0.39 ENSMUST00000020820.2
mitochondrial ribosomal protein L22
chr9_+_119170360 0.38 ENSMUST00000039784.12
acetyl-Coenzyme A acyltransferase 1A
chr2_+_30331839 0.37 ENSMUST00000131476.8
protein phosphatase 2 protein activator
chr14_-_76248274 0.37 ENSMUST00000088922.5
general transcription factor IIF, polypeptide 2
chr5_+_145020910 0.37 ENSMUST00000124379.3
actin related protein 2/3 complex, subunit 1A
chr8_-_13939964 0.36 ENSMUST00000209371.2
coordinator of PRMT5, differentiation stimulator
chr2_+_91376650 0.36 ENSMUST00000099716.11
ENSMUST00000046769.16
ENSMUST00000111337.3
cytoskeleton associated protein 5
chr5_-_5564730 0.36 ENSMUST00000115445.8
ENSMUST00000179804.8
ENSMUST00000125110.2
ENSMUST00000115446.8
claudin 12
chr16_-_30152708 0.35 ENSMUST00000229503.2
ATPase type 13A3
chr7_-_110443557 0.35 ENSMUST00000177462.8
ENSMUST00000176716.3
ENSMUST00000176746.8
ENSMUST00000177236.8
ring finger protein 141
chr6_-_13607963 0.35 ENSMUST00000031554.9
ENSMUST00000149123.3
transmembrane protein 168
chr9_+_21634779 0.35 ENSMUST00000034713.9
low density lipoprotein receptor
chr1_-_106687457 0.35 ENSMUST00000010049.6
3-ketodihydrosphingosine reductase
chrX_-_133442596 0.34 ENSMUST00000054213.5
translocase of inner mitochondrial membrane 8A1
chr16_+_16688591 0.34 ENSMUST00000232080.2
topoisomerase (DNA) III beta
chrM_+_8603 0.34 ENSMUST00000082409.1
mitochondrially encoded cytochrome c oxidase III
chrX_-_93256244 0.34 ENSMUST00000113922.2
eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked
chr19_+_8779903 0.34 ENSMUST00000172175.3
zinc finger and BTB domain containing 3
chr6_-_69282389 0.34 ENSMUST00000103350.3
immunoglobulin kappa variable 4-68
chr10_-_115198093 0.34 ENSMUST00000219890.2
ENSMUST00000218731.2
ENSMUST00000217887.2
ENSMUST00000092170.7
transmembrane protein 19
chr17_+_27775613 0.34 ENSMUST00000231780.2
ENSMUST00000232253.2
ENSMUST00000232552.2
ENSMUST00000117600.9
high mobility group AT-hook 1
chr6_+_17749169 0.33 ENSMUST00000053148.14
ENSMUST00000115417.4
suppression of tumorigenicity 7
chr5_+_145020640 0.32 ENSMUST00000031625.15
actin related protein 2/3 complex, subunit 1A
chr9_+_66853343 0.32 ENSMUST00000040917.14
ENSMUST00000127896.8
ribosomal protein S27-like
chrX_+_138511360 0.32 ENSMUST00000113026.2
ring finger protein 128
chr2_-_29677634 0.32 ENSMUST00000177467.8
ENSMUST00000113807.10
TruB pseudouridine (psi) synthase family member 2
chr9_-_21671571 0.31 ENSMUST00000217382.2
ENSMUST00000214149.2
ENSMUST00000098942.6
ENSMUST00000216057.2
SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr3_+_90383425 0.31 ENSMUST00000001042.10
interleukin enhancer binding factor 2
chr1_+_160898283 0.31 ENSMUST00000028035.14
ENSMUST00000111620.10
ENSMUST00000111618.8
centromere protein L
chr10_-_129107354 0.31 ENSMUST00000204573.3
olfactory receptor 777
chr5_+_38233901 0.30 ENSMUST00000146864.6
syntaxin 18
chr12_+_85157607 0.30 ENSMUST00000053811.10
dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
chr9_+_113641615 0.30 ENSMUST00000111838.10
ENSMUST00000166734.10
ENSMUST00000214522.2
ENSMUST00000163895.3
CLIP associating protein 2
chr10_+_127257077 0.30 ENSMUST00000168780.8
R3H domain containing 2
chr7_+_126575752 0.30 ENSMUST00000206346.2
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)
chr10_-_62178453 0.29 ENSMUST00000143179.2
ENSMUST00000130422.8
hexokinase 1
chr10_+_81554753 0.29 ENSMUST00000085664.6
zinc finger protein 433
chr14_+_79086492 0.29 ENSMUST00000040990.7
von Willebrand factor A domain containing 8
chr3_+_88486921 0.29 ENSMUST00000193934.6
ENSMUST00000192495.6
ENSMUST00000035785.9
signal sequence receptor, beta
chr17_+_27775637 0.28 ENSMUST00000117254.9
ENSMUST00000231243.2
ENSMUST00000231358.2
ENSMUST00000118570.2
ENSMUST00000231796.2
high mobility group AT-hook 1
chr7_-_127494750 0.28 ENSMUST00000033074.8
vitamin K epoxide reductase complex, subunit 1
chr6_-_51443602 0.28 ENSMUST00000203253.2
heterogeneous nuclear ribonucleoprotein A2/B1
chr18_+_47245204 0.27 ENSMUST00000234633.2
heat shock protein 1 (chaperonin 10), related sequence 1
chr16_-_90607251 0.27 ENSMUST00000140920.2
URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
chr15_-_8740218 0.27 ENSMUST00000005493.14
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr9_+_74959259 0.27 ENSMUST00000170310.2
ENSMUST00000166549.2
cAMP-regulated phosphoprotein 19
chr15_+_6673167 0.27 ENSMUST00000163073.2
FYN binding protein
chr18_+_31742565 0.27 ENSMUST00000164667.2
RIKEN cDNA B930094E09 gene
chr6_-_115014777 0.27 ENSMUST00000174848.8
ENSMUST00000032461.12
TAM41 mitochondrial translocator assembly and maintenance homolog
chr9_-_22028370 0.26 ENSMUST00000213233.2
ELF1 homolog, elongation factor 1
chr5_-_124233812 0.26 ENSMUST00000031354.11
ATP-binding cassette, sub-family B (MDR/TAP), member 9
chr9_+_64188857 0.25 ENSMUST00000215031.2
ENSMUST00000213165.2
ENSMUST00000213289.2
ENSMUST00000216594.2
ENSMUST00000034964.7
timeless interacting protein
chr15_-_37008011 0.25 ENSMUST00000226671.2
zinc finger protein 706
chr9_+_21437440 0.25 ENSMUST00000086361.12
ENSMUST00000173769.3
cDNA sequence AB124611
chr8_-_106692668 0.24 ENSMUST00000116429.9
ENSMUST00000034370.17
solute carrier family 12, member 4
chr5_+_30824121 0.24 ENSMUST00000144742.6
ENSMUST00000149759.2
ENSMUST00000199320.5
centromere protein A
chr17_+_28911529 0.24 ENSMUST00000114752.3
mitogen-activated protein kinase 14
chr4_+_3940747 0.24 ENSMUST00000119403.2
coiled-coil-helix-coiled-coil-helix domain containing 7
chr18_+_37827413 0.24 ENSMUST00000193414.2
protocadherin gamma subfamily A, 5
chr8_-_85696040 0.24 ENSMUST00000214133.2
ENSMUST00000147812.8
predicted gene, 49661
ribonuclease H2, large subunit
chr12_+_65272287 0.24 ENSMUST00000046331.5
ENSMUST00000221658.2
WD repeat domain 20, retrogene
chr10_-_115197775 0.24 ENSMUST00000217848.2
transmembrane protein 19
chr9_-_53521585 0.24 ENSMUST00000034547.6
acetyl-Coenzyme A acetyltransferase 1
chr16_+_16688692 0.23 ENSMUST00000232547.2
topoisomerase (DNA) III beta
chr8_-_85573489 0.23 ENSMUST00000003912.7
calreticulin
chr2_-_84481101 0.23 ENSMUST00000111691.2
catenin (cadherin associated protein), delta 1
chr12_+_55883101 0.23 ENSMUST00000059250.8
breast cancer metastasis-suppressor 1-like
chr5_-_146731810 0.23 ENSMUST00000085614.6
ubiquitin specific peptidase 12
chr4_+_102446883 0.23 ENSMUST00000097949.11
ENSMUST00000106901.2
phosphodiesterase 4B, cAMP specific
chr2_-_37249247 0.22 ENSMUST00000112940.8
ENSMUST00000009174.15
phosducin-like
chr9_-_119170456 0.22 ENSMUST00000139870.2
myeloid differentiation primary response gene 88
chr2_-_5838489 0.22 ENSMUST00000128467.4
cell division cycle 123
chr3_+_88486908 0.22 ENSMUST00000195014.6
signal sequence receptor, beta
chr6_-_129449739 0.22 ENSMUST00000112076.9
ENSMUST00000184581.3
C-type lectin domain family 7, member a
chr2_+_120807498 0.22 ENSMUST00000067582.14
transmembrane protein 62
chr2_+_112323271 0.22 ENSMUST00000003705.12
apoptosis, caspase activation inhibitor
chr1_-_93373145 0.21 ENSMUST00000186787.7
high density lipoprotein (HDL) binding protein
chr19_+_43741550 0.21 ENSMUST00000153295.2
cutC copper transporter
chr11_-_30218167 0.21 ENSMUST00000006629.14
spectrin beta, non-erythrocytic 1
chr2_-_84255602 0.21 ENSMUST00000074262.9
calcitonin receptor-like
chr4_-_43710231 0.20 ENSMUST00000217544.2
ENSMUST00000107862.3
olfactory receptor 71
chr7_+_140521450 0.20 ENSMUST00000164580.3
ENSMUST00000079403.11
protein glucosylgalactosylhydroxylysine glucosidase
chr11_+_106642052 0.20 ENSMUST00000147326.9
ENSMUST00000182896.8
ENSMUST00000182908.8
ENSMUST00000086353.11
mast cell immunoglobulin like receptor 1
chr11_+_109434519 0.20 ENSMUST00000106696.2
arylsulfatase G
chr4_+_5724305 0.20 ENSMUST00000108380.2
family with sequence similarity 110, member B
chr2_+_85809620 0.20 ENSMUST00000056849.3
olfactory receptor 1030
chr17_+_28226319 0.19 ENSMUST00000139173.3
ankyrin repeat and SAM domain containing 1
chr1_-_80255156 0.19 ENSMUST00000168372.2
cullin 3
chr16_+_16688605 0.19 ENSMUST00000232581.2
ENSMUST00000231812.2
ENSMUST00000232017.2
ENSMUST00000023465.16
ENSMUST00000232231.2
ENSMUST00000232200.2
topoisomerase (DNA) III beta
chr12_+_79344056 0.18 ENSMUST00000171210.3
RAD51 paralog B
chr12_+_80690985 0.18 ENSMUST00000219405.2
ENSMUST00000085245.7
solute carrier family 39 (zinc transporter), member 9
chr12_+_10440755 0.18 ENSMUST00000020947.7
retinol dehydrogenase 14 (all-trans and 9-cis)
chr15_-_100322089 0.18 ENSMUST00000154331.2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr18_-_39620115 0.18 ENSMUST00000097592.9
ENSMUST00000115571.8
nuclear receptor subfamily 3, group C, member 1
chr9_-_59260713 0.18 ENSMUST00000026265.8
Bardet-Biedl syndrome 4 (human)
chr9_+_35334878 0.18 ENSMUST00000154652.8
cell adhesion molecule-related/down-regulated by oncogenes
chr11_-_59054521 0.17 ENSMUST00000137433.2
ENSMUST00000054523.6
IBA57 homolog, iron-sulfur cluster assembly
chr15_+_102234802 0.17 ENSMUST00000169637.8
prefoldin 5
chr9_-_15212849 0.17 ENSMUST00000034414.10
RIKEN cDNA 4931406C07 gene
chr5_+_115417725 0.17 ENSMUST00000040421.11
coenzyme Q5 methyltransferase
chr2_+_174292471 0.17 ENSMUST00000016399.6
tubulin, beta 1 class VI
chr7_+_107411470 0.17 ENSMUST00000208563.3
ENSMUST00000214253.2
olfactory receptor 467
chr9_-_8134295 0.17 ENSMUST00000037397.8
centrosomal protein 126
chr1_+_87983099 0.16 ENSMUST00000138182.8
ENSMUST00000113142.10
UDP glycosyltransferase 1 family, polypeptide A10
chr13_-_43634695 0.16 ENSMUST00000144326.4
RAN binding protein 9
chr12_-_85335193 0.16 ENSMUST00000121930.2
acylphosphatase 1, erythrocyte (common) type
chr4_+_43493344 0.16 ENSMUST00000030181.12
ENSMUST00000107922.3
coiled-coil domain containing 107
chr3_-_105861497 0.16 ENSMUST00000199311.2
ATP synthase peripheral stalk-membrane subunit b
chr17_+_37274714 0.16 ENSMUST00000209623.2
RNA polymerase I subunit H, antisense
chr15_-_100322934 0.16 ENSMUST00000123461.8
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr2_+_109721189 0.16 ENSMUST00000028583.8
lin-7 homolog C (C. elegans)
chr8_+_124204598 0.16 ENSMUST00000001520.13
AFG3-like AAA ATPase 1
chr11_-_79418500 0.16 ENSMUST00000154415.2
ecotropic viral integration site 2a
chr1_+_87983189 0.15 ENSMUST00000173325.2
UDP glycosyltransferase 1 family, polypeptide A10
chr11_-_84020382 0.15 ENSMUST00000018795.13
transcriptional adaptor 2A
chr2_-_85593110 0.15 ENSMUST00000214958.2
olfactory receptor 1012
chr6_-_129655868 0.15 ENSMUST00000118447.2
ENSMUST00000169545.8
ENSMUST00000032270.13
ENSMUST00000032271.13
killer cell lectin-like receptor subfamily C, member 1
chr17_-_15718542 0.15 ENSMUST00000014913.11
ENSMUST00000231341.2
proteasome (prosome, macropain) subunit, beta type 1
chr14_-_101846551 0.15 ENSMUST00000100340.4
TBC1 domain family, member 4
chr6_+_67873135 0.15 ENSMUST00000103310.3
immunoglobulin kappa variable 14-126
chr10_+_128067964 0.15 ENSMUST00000125289.8
ENSMUST00000105242.8
timeless circadian clock 1
chr14_-_55822696 0.14 ENSMUST00000022828.9
ER membrane protein complex subunit 9
chr14_+_26722319 0.14 ENSMUST00000035433.10
homeobox gene expressed in ES cells
chr9_+_106699073 0.14 ENSMUST00000159645.8
DDB1 and CUL4 associated factor 1
chr4_-_82768958 0.14 ENSMUST00000139401.2
zinc finger, DHHC domain containing 21
chrX_-_133012600 0.14 ENSMUST00000033610.13
NADPH oxidase 1
chr2_-_68302612 0.14 ENSMUST00000102715.4
serine/threonine kinase 39
chr8_+_71995554 0.14 ENSMUST00000034272.9
multivesicular body subunit 12A
chr16_-_38342949 0.14 ENSMUST00000002925.6
translocase of inner mitochondrial membrane domain containing 1
chr11_+_113575208 0.14 ENSMUST00000042227.15
ENSMUST00000123466.2
ENSMUST00000106621.4
DNA segment, Chr 11, Wayne State University 47, expressed
chr3_+_66893280 0.14 ENSMUST00000161726.2
ENSMUST00000160504.2
arginine/serine-rich coiled-coil 1
chr7_-_99994257 0.14 ENSMUST00000207634.2
protein phosphatase methylesterase 1
chr7_+_132212349 0.14 ENSMUST00000033241.6
ENSMUST00000106170.8
phospholysine phosphohistidine inorganic pyrophosphate phosphatase
chr12_-_104964936 0.14 ENSMUST00000109927.2
ENSMUST00000095439.11
spectrin repeat containing, nuclear envelope family member 3
chr18_-_32044877 0.14 ENSMUST00000054984.8
SFT2 domain containing 3
chr12_-_65113457 0.13 ENSMUST00000221608.2
FK506 binding protein 3
chr5_-_138617952 0.13 ENSMUST00000063262.11
ENSMUST00000085852.11
ENSMUST00000110905.9
zinc finger protein 68
chr12_+_65272495 0.13 ENSMUST00000221980.2
WD repeat domain 20, retrogene
chr17_+_56312672 0.13 ENSMUST00000133998.8
MPN domain containing
chr11_+_100978103 0.13 ENSMUST00000107302.8
ENSMUST00000107303.10
ENSMUST00000017945.15
ENSMUST00000149597.2
MAX-like protein X

Network of associatons between targets according to the STRING database.

First level regulatory network of Prrx1_Isx_Prrxl1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0018931 hexitol metabolic process(GO:0006059) naphthalene metabolic process(GO:0018931) naphthalene-containing compound metabolic process(GO:0090420)
0.4 1.3 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.4 1.1 GO:0009107 lipoate biosynthetic process(GO:0009107)
0.3 0.9 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.3 0.8 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.2 0.6 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.2 1.3 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.2 1.0 GO:0002188 translation reinitiation(GO:0002188)
0.2 0.8 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.1 0.7 GO:0006566 threonine metabolic process(GO:0006566)
0.1 2.8 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 3.9 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 0.4 GO:1904959 regulation of cytochrome-c oxidase activity(GO:1904959)
0.1 1.4 GO:0008228 opsonization(GO:0008228)
0.1 0.4 GO:0030472 mitotic spindle organization in nucleus(GO:0030472)
0.1 0.5 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.1 0.4 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.1 2.0 GO:0071285 cellular response to lithium ion(GO:0071285)
0.1 0.7 GO:2001205 negative regulation of osteoclast development(GO:2001205)
0.1 0.3 GO:1990428 miRNA transport(GO:1990428)
0.1 0.6 GO:0038109 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Fc-epsilon receptor signaling pathway(GO:0038095) Kit signaling pathway(GO:0038109)
0.1 0.6 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.1 0.4 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.1 0.8 GO:0006265 DNA topological change(GO:0006265)
0.1 0.5 GO:0009235 cobalamin metabolic process(GO:0009235)
0.1 0.2 GO:0006550 isoleucine catabolic process(GO:0006550)
0.1 0.1 GO:1903487 regulation of lactation(GO:1903487)
0.1 0.2 GO:0002501 MHC protein complex assembly(GO:0002396) peptide antigen assembly with MHC protein complex(GO:0002501)
0.1 0.5 GO:0051661 maintenance of centrosome location(GO:0051661)
0.1 0.3 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187)
0.1 0.3 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 0.4 GO:0015676 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.1 0.3 GO:1902953 positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
0.1 0.4 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 0.4 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.1 0.2 GO:2000338 chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
0.1 0.3 GO:1904975 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
0.1 0.2 GO:0009744 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.1 0.3 GO:0048478 replication fork protection(GO:0048478)
0.0 0.1 GO:1990164 histone H2A phosphorylation(GO:1990164)
0.0 0.2 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.0 0.1 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0 0.2 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.0 0.1 GO:0061341 dichotomous subdivision of terminal units involved in lung branching(GO:0060448) non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.0 0.2 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.5 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909)
0.0 0.4 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.0 0.2 GO:0060690 epithelial cell differentiation involved in salivary gland development(GO:0060690)
0.0 0.2 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.1 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.0 0.3 GO:0061621 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.1 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734)
0.0 0.5 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.0 0.2 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.0 0.2 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.2 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) positive regulation of interleukin-12 secretion(GO:2001184)
0.0 0.3 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.1 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.0 0.6 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.2 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 1.0 GO:0008206 bile acid metabolic process(GO:0008206)
0.0 0.9 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.2 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.0 0.3 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.1 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.0 0.3 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin biosynthetic process(GO:0032049)
0.0 0.1 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.1 GO:1903772 regulation of viral budding via host ESCRT complex(GO:1903772)
0.0 0.5 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.2 GO:1905244 regulation of modification of synaptic structure(GO:1905244)
0.0 0.1 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 0.3 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.0 0.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.4 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.3 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.2 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.3 GO:0033004 negative regulation of mast cell activation(GO:0033004)
0.0 1.3 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.1 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.0 0.2 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.1 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.3 GO:0042407 cristae formation(GO:0042407)
0.0 0.2 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.0 0.2 GO:0007182 common-partner SMAD protein phosphorylation(GO:0007182)
0.0 0.1 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.0 0.1 GO:0061193 taste bud development(GO:0061193)
0.0 0.1 GO:2001200 positive regulation of dendritic cell differentiation(GO:2001200)
0.0 0.2 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.0 0.1 GO:0044268 multicellular organismal protein metabolic process(GO:0044268)
0.0 0.1 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.1 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.1 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0 0.1 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.1 GO:0015862 uridine transport(GO:0015862)
0.0 0.3 GO:0055070 copper ion homeostasis(GO:0055070)
0.0 0.7 GO:0006284 base-excision repair(GO:0006284)
0.0 0.3 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.7 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.1 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.1 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 0.2 GO:0071459 kinetochore assembly(GO:0051382) protein localization to chromosome, centromeric region(GO:0071459)
0.0 0.0 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.1 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
0.0 0.1 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.2 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 0.0 GO:0009216 deoxyribonucleoside triphosphate biosynthetic process(GO:0009202) purine deoxyribonucleoside triphosphate biosynthetic process(GO:0009216)
0.0 0.1 GO:0010519 negative regulation of phospholipase activity(GO:0010519)
0.0 0.1 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 0.1 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.1 GO:0009441 fatty acid alpha-oxidation(GO:0001561) glycolate metabolic process(GO:0009441)
0.0 0.3 GO:0006103 2-oxoglutarate metabolic process(GO:0006103)
0.0 0.0 GO:0018343 protein farnesylation(GO:0018343)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.3 1.4 GO:0097454 Schwann cell microvillus(GO:0097454)
0.2 0.5 GO:0000814 ESCRT II complex(GO:0000814)
0.2 0.5 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.1 0.3 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.1 0.3 GO:1904511 cortical microtubule plus-end(GO:1903754) cytoplasmic microtubule plus-end(GO:1904511)
0.1 0.7 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 0.5 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1 0.3 GO:0030312 external encapsulating structure(GO:0030312)
0.1 4.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 1.4 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 0.6 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 0.4 GO:0031262 Ndc80 complex(GO:0031262)
0.1 0.7 GO:0030891 VCB complex(GO:0030891)
0.1 0.4 GO:0070826 paraferritin complex(GO:0070826)
0.1 0.2 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
0.1 0.4 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 0.9 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.3 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 3.0 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.5 GO:0000235 astral microtubule(GO:0000235)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.8 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.2 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.2 GO:0005745 m-AAA complex(GO:0005745)
0.0 0.3 GO:0042629 mast cell granule(GO:0042629)
0.0 0.3 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.5 GO:0034709 methylosome(GO:0034709)
0.0 1.2 GO:0001533 cornified envelope(GO:0001533)
0.0 0.3 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.2 GO:0000125 PCAF complex(GO:0000125)
0.0 0.2 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.2 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 0.2 GO:0005827 polar microtubule(GO:0005827)
0.0 0.2 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 1.0 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.3 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.6 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 2.2 GO:0005811 lipid particle(GO:0005811)
0.0 0.2 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.0 0.1 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0032437 cuticular plate(GO:0032437)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 0.1 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.2 GO:0005915 zonula adherens(GO:0005915)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.5 GO:0043596 nuclear replication fork(GO:0043596)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 0.0 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.0 GO:1990716 axonemal central apparatus(GO:1990716)
0.0 0.1 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0033797 selenate reductase activity(GO:0033797)
0.3 1.0 GO:0008775 acetate CoA-transferase activity(GO:0008775)
0.3 3.6 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.3 1.6 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.3 0.8 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.2 1.4 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.2 0.7 GO:0004793 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.1 0.8 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.8 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 1.4 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 1.3 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1 0.3 GO:0016900 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.1 0.4 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160)
0.1 0.2 GO:0008106 alcohol dehydrogenase (NADP+) activity(GO:0008106)
0.1 0.3 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.1 0.5 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 0.5 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 0.3 GO:0016748 succinyltransferase activity(GO:0016748)
0.1 0.2 GO:0004948 calcitonin receptor activity(GO:0004948)
0.1 0.6 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1 0.3 GO:0015440 peptide-transporting ATPase activity(GO:0015440)
0.1 0.4 GO:0015094 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 0.9 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.1 1.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.2 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.1 0.2 GO:0070976 TIR domain binding(GO:0070976)
0.1 0.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.2 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.3 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.2 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.4 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.6 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.0 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558)
0.0 0.4 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.1 GO:0003692 left-handed Z-DNA binding(GO:0003692)
0.0 2.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.3 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.2 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.1 GO:0019150 D-ribulokinase activity(GO:0019150)
0.0 0.1 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.2 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.3 GO:0008494 translation activator activity(GO:0008494)
0.0 0.2 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.5 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.2 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.3 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.6 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.2 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.1 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.2 GO:0034452 dynactin binding(GO:0034452)
0.0 0.4 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0 0.6 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.2 GO:0000150 recombinase activity(GO:0000150)
0.0 0.1 GO:0089720 caspase binding(GO:0089720)
0.0 0.1 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.0 0.1 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 0.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.2 GO:0015926 glucosidase activity(GO:0015926)
0.0 0.2 GO:0051525 mitogen-activated protein kinase p38 binding(GO:0048273) NFAT protein binding(GO:0051525)
0.0 0.5 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.6 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.0 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 0.1 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0 0.1 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.5 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.1 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.3 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.5 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.1 GO:0004568 chitinase activity(GO:0004568)
0.0 0.2 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.1 GO:0004832 valine-tRNA ligase activity(GO:0004832)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.6 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 2.1 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.7 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.7 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.5 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.9 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.4 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.5 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 0.6 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 1.8 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 1.6 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 3.4 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 1.3 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.6 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.7 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.7 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.1 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.5 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.3 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.4 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.8 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.2 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.2 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.5 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.7 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.3 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.1 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.4 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions