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avrg: GFI1 WT vs 36n/n vs KD

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Results for Rad21_Smc3

Z-value: 2.16

Motif logo

Transcription factors associated with Rad21_Smc3

Gene Symbol Gene ID Gene Info
ENSMUSG00000022314.11 RAD21 cohesin complex component
ENSMUSG00000024974.11 structural maintenance of chromosomes 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Smc3mm39_v1_chr19_+_53588808_53588869-0.913.0e-02Click!
Rad21mm39_v1_chr15_-_51855073_518551590.904.0e-02Click!

Activity profile of Rad21_Smc3 motif

Sorted Z-values of Rad21_Smc3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_126866682 1.68 ENSMUST00000040560.11
Ts translation elongation factor, mitochondrial
chr6_-_52217821 1.60 ENSMUST00000121043.2
homeobox A10
chr16_+_16714333 1.55 ENSMUST00000027373.12
ENSMUST00000232247.2
protein phosphatase 1F (PP2C domain containing)
chr19_-_10857734 1.41 ENSMUST00000133303.8
transmembrane protein 109
chr8_+_22682816 1.36 ENSMUST00000033866.9
vacuolar protein sorting 36
chr1_-_133537953 1.26 ENSMUST00000164574.2
ENSMUST00000166291.8
ENSMUST00000164096.2
ENSMUST00000166915.8
small nuclear ribonucleoprotein E
chr7_-_44785603 1.25 ENSMUST00000209467.2
predicted gene 45713
chr7_-_108769719 1.23 ENSMUST00000208136.2
ENSMUST00000036992.9
LIM domain only 1
chr11_-_70873773 1.20 ENSMUST00000078528.7
complement component 1, q subcomponent binding protein
chr14_-_14389372 1.19 ENSMUST00000023924.4
ribonuclease P 14 subunit
chr14_+_8348779 1.19 ENSMUST00000022256.5
proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
chr17_-_56343531 1.17 ENSMUST00000233803.2
SH3-domain GRB2-like 1
chr9_+_106088798 1.13 ENSMUST00000216850.2
twinfilin actin binding protein 2
chr12_-_110669076 1.10 ENSMUST00000155242.8
heat shock protein 90, alpha (cytosolic), class A member 1
chr5_+_31078911 1.07 ENSMUST00000201571.4
ketohexokinase
chr6_-_85114725 1.06 ENSMUST00000174769.2
ENSMUST00000174286.3
ENSMUST00000045986.8
sepiapterin reductase
chr4_-_132072988 1.05 ENSMUST00000030726.13
regulator of chromosome condensation 1
chr4_+_134123631 1.03 ENSMUST00000105869.9
platelet-activating factor acetylhydrolase 2
chr8_-_108151661 1.01 ENSMUST00000003946.9
NIN1/RPN12 binding protein 1 homolog
chr17_+_34423054 1.01 ENSMUST00000138491.2
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
chr5_+_24598633 1.00 ENSMUST00000138168.3
ENSMUST00000115077.8
ATP-binding cassette, sub-family B (MDR/TAP), member 8
chr4_-_132073048 0.99 ENSMUST00000084250.11
regulator of chromosome condensation 1
chrX_-_101232978 0.97 ENSMUST00000033683.8
ribosomal protein S4, X-linked
chr3_-_84063067 0.95 ENSMUST00000047368.8
meiotic nuclear divisions 1
chr15_-_36496880 0.94 ENSMUST00000228601.2
ENSMUST00000057486.9
ankyrin repeat domain 46
chr19_+_43741550 0.93 ENSMUST00000153295.2
cutC copper transporter
chr8_+_107757847 0.93 ENSMUST00000034388.10
vacuolar protein sorting 4A
chr15_+_74593041 0.93 ENSMUST00000070923.3
thioesterase superfamily member 6
chr5_-_117254037 0.92 ENSMUST00000086471.12
suppressor of defective silencing 3 homolog (S. cerevisiae)
chr5_+_115373895 0.91 ENSMUST00000081497.13
processing of precursor 5, ribonuclease P/MRP family (S. cerevisiae)
chr4_+_152123772 0.87 ENSMUST00000084116.13
ENSMUST00000103197.5
nucleolar protein 9
chr5_+_108048697 0.86 ENSMUST00000153590.2
ribosomal protein L5
chr3_+_142266113 0.84 ENSMUST00000106221.8
guanylate binding protein 3
chr8_-_70078152 0.83 ENSMUST00000121886.8
zinc finger protein 868
chr4_+_127137577 0.81 ENSMUST00000142029.2
small integral membrane protein 12
chr1_+_44159106 0.81 ENSMUST00000114709.3
ENSMUST00000129068.2
basic, immunoglobulin-like variable motif containing
chr2_-_66086919 0.81 ENSMUST00000125446.3
ENSMUST00000102718.10
tetratricopeptide repeat domain 21B
chr3_-_107603778 0.80 ENSMUST00000029490.15
S-adenosylhomocysteine hydrolase-like 1
chr10_-_126866658 0.80 ENSMUST00000120547.2
ENSMUST00000152054.8
Ts translation elongation factor, mitochondrial
chr5_-_117254146 0.80 ENSMUST00000166397.3
suppressor of defective silencing 3 homolog (S. cerevisiae)
chr16_-_10603389 0.79 ENSMUST00000229866.2
ENSMUST00000038099.6
suppressor of cytokine signaling 1
chr17_+_25992761 0.77 ENSMUST00000237541.2
cytosolic iron-sulfur assembly component 3
chr3_+_96552895 0.75 ENSMUST00000119365.8
ENSMUST00000029744.6
integrin, alpha 10
chr4_-_45108038 0.75 ENSMUST00000107809.9
ENSMUST00000107808.3
ENSMUST00000107807.2
ENSMUST00000107810.3
translocase of outer mitochondrial membrane 5
chr16_+_17870724 0.75 ENSMUST00000143343.8
DiGeorge syndrome critical region gene 6
chr2_+_26476619 0.74 ENSMUST00000239075.2
ENSMUST00000174211.8
ENSMUST00000145575.10
ENSMUST00000173920.9
EGF-like domain 7
chr4_+_124608569 0.73 ENSMUST00000030734.5
splicing factor 3a, subunit 3
chr7_+_34818709 0.73 ENSMUST00000205391.2
ENSMUST00000042985.11
CCAAT/enhancer binding protein (C/EBP), alpha
chr5_-_143301113 0.73 ENSMUST00000046418.3
RIKEN cDNA E130309D02 gene
chr15_+_100659622 0.73 ENSMUST00000023776.13
solute carrier family 4 (anion exchanger), member 8
chr4_+_86493905 0.72 ENSMUST00000091064.8
Ras-related GTP binding A
chr11_-_3864664 0.72 ENSMUST00000109995.2
ENSMUST00000051207.2
solute carrier family 35, member E4
chr4_-_126362372 0.71 ENSMUST00000097888.10
ENSMUST00000239399.2
argonaute RISC catalytic subunit 1
chr5_+_124045238 0.70 ENSMUST00000023869.15
density-regulated protein
chr2_-_157988303 0.67 ENSMUST00000103122.10
transglutaminase 2, C polypeptide
chr13_-_55684317 0.67 ENSMUST00000021956.9
ENSMUST00000224765.2
DEAD box helicase 41
chr1_+_161796854 0.66 ENSMUST00000160881.2
ENSMUST00000159648.2
phosphatidylinositol glycan anchor biosynthesis, class C
chr6_+_124547247 0.66 ENSMUST00000184647.2
complement component 1, r subcomponent B
chr7_+_16043502 0.65 ENSMUST00000002152.13
BCL2 binding component 3
chr5_+_64317550 0.64 ENSMUST00000101195.9
TBC1 domain family, member 1
chr19_+_7394951 0.64 ENSMUST00000159348.3
RIKEN cDNA 2700081O15 gene
chr7_-_46360066 0.62 ENSMUST00000143082.4
serum amyloid A-like 1
chr11_-_82781369 0.62 ENSMUST00000092844.13
ENSMUST00000021033.16
ENSMUST00000018985.15
RAD51 paralog D
chr12_+_55431007 0.62 ENSMUST00000163070.8
proteasome subunit alpha 6
chr5_+_115697526 0.62 ENSMUST00000086519.12
ENSMUST00000156359.2
ENSMUST00000152976.2
ribosomal protein, large, P0
chr4_-_141345549 0.61 ENSMUST00000053263.9
transmembrane protein 82
chr7_-_120269462 0.61 ENSMUST00000127845.2
ENSMUST00000208635.2
ENSMUST00000033178.4
PDZ domain containing 9
chr12_+_24758240 0.60 ENSMUST00000020980.12
ribonucleotide reductase M2
chr3_-_5641171 0.60 ENSMUST00000071280.8
ENSMUST00000195855.6
ENSMUST00000165309.8
ENSMUST00000164828.8
peroxisomal biogenesis factor 2
chr17_-_56343625 0.60 ENSMUST00000003268.11
SH3-domain GRB2-like 1
chr12_+_24758724 0.60 ENSMUST00000153058.8
ribonucleotide reductase M2
chr3_+_54642957 0.59 ENSMUST00000044567.4
asparagine-linked glycosylation 5 (dolichyl-phosphate beta-glucosyltransferase)
chrX_+_20529137 0.59 ENSMUST00000001989.9
ubiquitin-like modifier activating enzyme 1
chr19_+_5012362 0.59 ENSMUST00000236917.2
mitochondrial ribosomal protein L11
chr16_-_20121108 0.58 ENSMUST00000048642.15
ENSMUST00000232036.2
presenilin associated, rhomboid-like
chr15_+_102378966 0.58 ENSMUST00000077037.13
ENSMUST00000229102.2
ENSMUST00000229618.2
ENSMUST00000229275.2
ENSMUST00000231089.2
ENSMUST00000229802.2
ENSMUST00000229854.2
ENSMUST00000108838.5
poly(rC) binding protein 2
chr12_+_24758968 0.57 ENSMUST00000154588.2
ribonucleotide reductase M2
chr7_-_126625739 0.57 ENSMUST00000205461.2
MYC-associated zinc finger protein (purine-binding transcription factor)
chr7_+_49428082 0.57 ENSMUST00000032715.13
protein arginine N-methyltransferase 3
chr6_+_124489364 0.56 ENSMUST00000068593.9
complement component 1, r subcomponent A
chr5_-_114266228 0.56 ENSMUST00000053657.13
ENSMUST00000149418.2
ENSMUST00000112279.2
alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase
chr2_-_93652882 0.56 ENSMUST00000111248.8
ENSMUST00000184931.8
ENSMUST00000145838.8
ENSMUST00000028623.13
exostosin glycosyltransferase 2
chr17_+_29487881 0.56 ENSMUST00000234845.2
ENSMUST00000235038.2
ENSMUST00000235050.2
ENSMUST00000120346.9
ENSMUST00000234377.2
ENSMUST00000235074.2
ENSMUST00000235040.2
ENSMUST00000234256.2
ENSMUST00000234459.2
cDNA sequence BC004004
chr4_+_126156118 0.55 ENSMUST00000030660.9
trafficking protein particle complex 3
chr3_-_89008406 0.55 ENSMUST00000200659.2
predicted gene 43738
chr12_-_26465253 0.55 ENSMUST00000020971.14
ring finger protein 144A
chr11_+_49135018 0.55 ENSMUST00000167400.8
ENSMUST00000081794.7
mannoside acetylglucosaminyltransferase 1
chr19_-_8691797 0.55 ENSMUST00000206797.2
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
chr5_-_130053120 0.54 ENSMUST00000161640.8
ENSMUST00000161884.2
ENSMUST00000161094.8
argininosuccinate lyase
chr3_-_87676239 0.54 ENSMUST00000173184.2
ENSMUST00000172621.8
ENSMUST00000174759.8
ENSMUST00000172590.8
ENSMUST00000079083.12
platelet endothelial aggregation receptor 1
chr12_-_112640626 0.53 ENSMUST00000001780.10
thymoma viral proto-oncogene 1
chr5_+_140317615 0.53 ENSMUST00000071881.10
ENSMUST00000050205.12
ENSMUST00000110827.8
nudix (nucleoside diphosphate linked moiety X)-type motif 1
chr15_-_76396151 0.53 ENSMUST00000023214.11
diacylglycerol O-acyltransferase 1
chr13_+_52000704 0.52 ENSMUST00000021903.3
growth arrest and DNA-damage-inducible 45 gamma
chr7_-_126625657 0.51 ENSMUST00000205568.2
MYC-associated zinc finger protein (purine-binding transcription factor)
chr9_-_44179348 0.51 ENSMUST00000169651.3
NLR family member X1
chr14_+_45567245 0.51 ENSMUST00000022380.9
proteasome (prosome, macropain) 26S subunit, ATPase, 6
chr7_+_127399776 0.51 ENSMUST00000046863.12
ENSMUST00000206674.2
ENSMUST00000106272.8
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr11_+_4085164 0.51 ENSMUST00000003677.11
ENSMUST00000145705.8
ring finger protein 215
chr7_-_45084012 0.51 ENSMUST00000107771.12
ENSMUST00000211666.2
RuvB-like protein 2
chr9_-_44179758 0.51 ENSMUST00000034621.16
ENSMUST00000168499.9
NLR family member X1
chr19_+_5012396 0.50 ENSMUST00000235229.2
mitochondrial ribosomal protein L11
chr6_+_88061464 0.50 ENSMUST00000032143.8
ribophorin I
chr4_+_140428777 0.50 ENSMUST00000138808.8
ENSMUST00000038893.6
regulator of chromosome condensation 2
chr5_+_124045552 0.50 ENSMUST00000166233.2
density-regulated protein
chr7_+_120442048 0.50 ENSMUST00000047875.16
eukaryotic elongation factor-2 kinase
chr4_-_43025756 0.50 ENSMUST00000098109.9
phosphatidylinositol glycan anchor biosynthesis, class O
chr7_+_127399789 0.49 ENSMUST00000125188.8
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr17_-_34109513 0.49 ENSMUST00000173386.2
ENSMUST00000114361.9
ENSMUST00000173492.9
kinesin family member C1
chr18_+_37898633 0.49 ENSMUST00000044851.8
protocadherin gamma subfamily A, 12
chr13_-_8921732 0.48 ENSMUST00000054251.13
ENSMUST00000176813.8
ENSMUST00000175958.2
WD repeat domain 37
chr14_+_55842002 0.48 ENSMUST00000138037.2
interferon regulatory factor 9
chr15_+_101184488 0.48 ENSMUST00000229525.2
ENSMUST00000230525.2
autophagy related 101
chr4_-_44072712 0.48 ENSMUST00000102936.9
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr2_+_131052283 0.47 ENSMUST00000110210.8
ENSMUST00000089506.12
ENSMUST00000110208.8
adaptor-related protein 5 complex, sigma 1 subunit
chr4_+_138926577 0.47 ENSMUST00000145368.8
capping protein (actin filament) muscle Z-line, beta
chr1_+_82817170 0.47 ENSMUST00000189220.7
ENSMUST00000113444.8
ArfGAP with FG repeats 1
chr19_-_8691460 0.47 ENSMUST00000206560.2
ENSMUST00000205538.2
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
chr6_-_71376277 0.47 ENSMUST00000149415.2
required for meiotic nuclear division 5 homolog A
chr12_+_70872266 0.46 ENSMUST00000057859.9
FERM domain containing 6
chrX_+_158315666 0.46 ENSMUST00000057180.13
Bclaf1 and Thrap3 family member 3
chr19_+_6450553 0.46 ENSMUST00000146831.8
ENSMUST00000035716.15
ENSMUST00000138555.8
ENSMUST00000167240.8
RAS, guanyl releasing protein 2
chr6_+_59185846 0.45 ENSMUST00000062626.4
tigger transposable element derived 2
chr6_+_108760025 0.44 ENSMUST00000032196.9
ADP-ribosylation factor-like 8B
chr4_-_43025792 0.44 ENSMUST00000067481.6
phosphatidylinositol glycan anchor biosynthesis, class O
chr19_+_5012336 0.44 ENSMUST00000237974.2
mitochondrial ribosomal protein L11
chr11_-_107080150 0.43 ENSMUST00000106757.8
ENSMUST00000018577.8
nucleolar protein 11
chr8_+_106412905 0.43 ENSMUST00000213019.2
capping protein regulator and myosin 1 linker 2
chr12_+_113120023 0.42 ENSMUST00000049271.13
tubulin epsilon and delta complex 1
chr10_-_10433831 0.42 ENSMUST00000019974.5
RAB32, member RAS oncogene family
chr3_+_154302311 0.42 ENSMUST00000192462.6
ENSMUST00000029850.15
crystallin, zeta
chr4_-_149222057 0.42 ENSMUST00000030813.10
centromere protein S
chr7_-_126625617 0.42 ENSMUST00000032916.6
MYC-associated zinc finger protein (purine-binding transcription factor)
chr13_+_51254852 0.42 ENSMUST00000095797.6
spindlin 1
chr17_-_66408461 0.41 ENSMUST00000024909.15
ENSMUST00000147484.2
NADH:ubiquinone oxidoreductase core subunit V2
chr8_-_105261262 0.41 ENSMUST00000162466.8
ENSMUST00000034349.10
NEDD8 activating enzyme E1 subunit 1
chr7_-_126611037 0.40 ENSMUST00000133172.2
major vault protein
chr3_+_133015846 0.40 ENSMUST00000029644.16
ENSMUST00000122334.8
pyrophosphatase (inorganic) 2
chr6_+_83078545 0.40 ENSMUST00000101254.9
coiled-coil domain containing 142
chr9_+_110162470 0.40 ENSMUST00000198761.5
ENSMUST00000197630.3
SREBF chaperone
chr8_-_41870077 0.40 ENSMUST00000033999.8
FSHD region gene 1
chr19_-_43741363 0.40 ENSMUST00000045562.6
cytochrome c oxidase assembly protein 15
chr9_+_45817795 0.40 ENSMUST00000039059.8
proprotein convertase subtilisin/kexin type 7
chr1_+_153625243 0.39 ENSMUST00000182722.8
ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)
chr7_+_45084300 0.39 ENSMUST00000211150.2
glycogen synthase 1, muscle
chr4_-_129467430 0.39 ENSMUST00000102596.8
lymphocyte protein tyrosine kinase
chr11_-_69470139 0.39 ENSMUST00000048139.12
WD repeat containing, antisense to Trp53
chr15_+_97682210 0.38 ENSMUST00000117892.2
ENSMUST00000229084.2
solute carrier family 48 (heme transporter), member 1
chr4_-_149221998 0.38 ENSMUST00000176124.8
ENSMUST00000177408.2
ENSMUST00000105695.2
centromere protein S
chr1_+_16175998 0.38 ENSMUST00000027053.8
retinol dehydrogenase 10 (all-trans)
chr11_-_62172164 0.38 ENSMUST00000072916.5
zinc finger SWIM-type containing 7
chr3_-_116301684 0.38 ENSMUST00000153005.2
RNA 3'-terminal phosphate cyclase
chr5_+_149601688 0.38 ENSMUST00000100404.6
beta-3-glucosyltransferase
chr1_-_150268470 0.38 ENSMUST00000006167.13
ENSMUST00000097547.10
odr4 GPCR localization factor homolog
chr8_+_70735477 0.38 ENSMUST00000087467.12
ENSMUST00000140212.8
ENSMUST00000110124.9
homer scaffolding protein 3
chrX_+_158315652 0.37 ENSMUST00000112464.8
Bclaf1 and Thrap3 family member 3
chr16_-_10994135 0.37 ENSMUST00000037633.16
zinc finger CCCH type containing 7 A
chr9_+_71123061 0.37 ENSMUST00000034723.6
aldehyde dehydrogenase family 1, subfamily A2
chr1_-_92576563 0.37 ENSMUST00000053144.4
otospiralin
chr5_-_134205559 0.37 ENSMUST00000076228.3
reculator of chromosome condensation 1 like
chr7_+_127400016 0.37 ENSMUST00000106271.2
ENSMUST00000138432.2
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr11_-_45835737 0.36 ENSMUST00000129820.8
U7 snRNP-specific Sm-like protein LSM11
chr3_-_105594865 0.36 ENSMUST00000090680.11
DEAD box helicase 20
chr16_-_16950241 0.36 ENSMUST00000023453.10
stromal cell-derived factor 2-like 1
chr19_-_42768374 0.35 ENSMUST00000069298.13
ENSMUST00000160455.8
ENSMUST00000162004.8
HPS1, biogenesis of lysosomal organelles complex 3 subunit 1
chr5_+_31079177 0.35 ENSMUST00000031053.15
ENSMUST00000202752.2
ketohexokinase
chr3_-_5641295 0.35 ENSMUST00000059021.10
peroxisomal biogenesis factor 2
chr10_-_17898938 0.35 ENSMUST00000220110.2
ABRA C-terminal like
chr19_+_43741513 0.35 ENSMUST00000112047.10
cutC copper transporter
chr11_-_62539284 0.35 ENSMUST00000057194.9
leucine rich repeat containing 75A
chr4_-_44073016 0.34 ENSMUST00000128439.8
ENSMUST00000140724.3
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr11_-_100986192 0.34 ENSMUST00000019447.15
proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein
chr14_+_31887739 0.34 ENSMUST00000111994.10
ENSMUST00000168114.8
ENSMUST00000168034.8
nuclear receptor coactivator 4
chr16_-_84532630 0.34 ENSMUST00000116584.2
mitochondrial ribosomal protein L39
chr1_+_153625161 0.33 ENSMUST00000086209.10
ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)
chr10_+_24745884 0.33 ENSMUST00000092646.13
ENSMUST00000020159.15
mediator complex subunit 23
chr17_+_25992742 0.33 ENSMUST00000134108.8
ENSMUST00000002350.11
cytosolic iron-sulfur assembly component 3
chr9_+_107765320 0.33 ENSMUST00000191906.6
ENSMUST00000035202.4
MON1 homolog A, secretory traffciking associated
chr1_-_16590244 0.32 ENSMUST00000144138.4
ENSMUST00000145092.8
ENSMUST00000131257.9
ENSMUST00000153966.9
ENSMUST00000162435.8
staufen double-stranded RNA binding protein 2
chr18_+_12776358 0.32 ENSMUST00000234966.2
ENSMUST00000025294.9
tetratricopeptide repeat domain 39C
chr13_-_9046020 0.32 ENSMUST00000222098.2
GTP binding protein 4
chr4_+_155915729 0.32 ENSMUST00000139651.8
ENSMUST00000084097.12
aurora kinase A interacting protein 1
chr2_-_152857239 0.31 ENSMUST00000028972.9
p53 and DNA damage regulated 1
chr3_-_120965327 0.31 ENSMUST00000170781.2
ENSMUST00000039761.12
ENSMUST00000106467.8
ENSMUST00000106466.10
ENSMUST00000164925.9
RWD domain containing 3
chr3_-_89905927 0.31 ENSMUST00000197725.5
ENSMUST00000197767.5
ENSMUST00000197786.5
ENSMUST00000079724.9
HCLS1 associated X-1
chr10_+_11157047 0.30 ENSMUST00000129456.8
F-box protein 30
chr1_-_38168697 0.30 ENSMUST00000027251.12
REV1, DNA directed polymerase
chr5_+_120787253 0.30 ENSMUST00000156722.2
RAS protein activator like 1 (GAP1 like)
chr14_+_66534478 0.30 ENSMUST00000022623.13
tripartite motif-containing 35
chr2_+_117080212 0.30 ENSMUST00000028825.5
family with sequence similarity 98, member B
chr19_+_6450641 0.29 ENSMUST00000113467.2
RAS, guanyl releasing protein 2
chr13_-_35211060 0.29 ENSMUST00000170538.8
ENSMUST00000163280.8
enoyl-Coenzyme A delta isomerase 2
chr9_-_57552844 0.29 ENSMUST00000216979.2
ENSMUST00000034863.8
c-src tyrosine kinase
chr6_+_83142902 0.29 ENSMUST00000077407.12
ENSMUST00000113913.8
ENSMUST00000130212.8
dynactin 1
chr11_+_50022167 0.29 ENSMUST00000093138.13
ENSMUST00000101270.5
TBC1 domain family, member 9B
chr7_+_45084257 0.29 ENSMUST00000003964.17
glycogen synthase 1, muscle
chr4_+_152018142 0.29 ENSMUST00000062904.11
DnaJ heat shock protein family (Hsp40) member C11
chr8_-_25592001 0.28 ENSMUST00000128715.8
pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2
chr18_-_10610048 0.28 ENSMUST00000115864.8
ENSMUST00000145320.2
ENSMUST00000097670.10
establishment of sister chromatid cohesion N-acetyltransferase 1
chr6_-_83752749 0.28 ENSMUST00000014892.8
testis expressed gene 261

Network of associatons between targets according to the STRING database.

First level regulatory network of Rad21_Smc3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.5 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.4 1.6 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.3 1.4 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.3 1.0 GO:0002481 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476) antigen processing and presentation of exogenous peptide antigen via MHC class Ib(GO:0002477) antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent(GO:0002481) cytosol to ER transport(GO:0046967)
0.3 0.9 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
0.3 0.9 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.3 0.8 GO:1903632 positive regulation of aminoacyl-tRNA ligase activity(GO:1903632)
0.2 1.2 GO:0060356 leucine import(GO:0060356)
0.2 1.2 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.2 0.7 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.2 2.3 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.2 1.2 GO:0002188 translation reinitiation(GO:0002188)
0.2 0.7 GO:0060709 glycogen cell differentiation involved in embryonic placenta development(GO:0060709)
0.2 0.5 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
0.2 0.5 GO:1901738 regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin A metabolic process(GO:1901738)
0.2 1.2 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.2 0.5 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.2 1.5 GO:0035754 B cell chemotaxis(GO:0035754)
0.2 0.5 GO:0042262 DNA protection(GO:0042262)
0.2 1.1 GO:0045585 regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.1 1.8 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 0.4 GO:2000813 negative regulation of barbed-end actin filament capping(GO:2000813)
0.1 0.5 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.1 1.5 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 0.4 GO:0036090 cleavage furrow ingression(GO:0036090)
0.1 1.3 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
0.1 1.5 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.1 0.5 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.1 0.5 GO:0098963 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
0.1 0.6 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.1 1.1 GO:0032532 regulation of microvillus length(GO:0032532)
0.1 0.8 GO:1903232 melanosome assembly(GO:1903232)
0.1 0.3 GO:1902071 positive regulation of cellular response to hypoxia(GO:1900039) regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.1 0.8 GO:0010533 regulation of activation of Janus kinase activity(GO:0010533)
0.1 0.9 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.1 3.8 GO:0051290 protein heterotetramerization(GO:0051290)
0.1 0.8 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.7 GO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280)
0.1 0.3 GO:0098917 retrograde trans-synaptic signaling(GO:0098917)
0.1 0.5 GO:0071898 regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.1 0.1 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.1 0.3 GO:2000409 positive regulation of T cell extravasation(GO:2000409)
0.1 0.7 GO:0000050 urea cycle(GO:0000050)
0.1 0.7 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.1 0.6 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.1 0.6 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.1 0.5 GO:0003383 apical constriction(GO:0003383)
0.1 0.3 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.1 1.1 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.1 0.5 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.1 0.2 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.8 GO:0002138 retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.1 0.6 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.2 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.1 0.4 GO:1900739 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.1 0.9 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.1 0.3 GO:0002268 follicular dendritic cell activation(GO:0002266) follicular dendritic cell differentiation(GO:0002268)
0.1 1.1 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.1 1.3 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.1 0.4 GO:0015886 heme transport(GO:0015886)
0.1 0.2 GO:0051030 snRNA transport(GO:0051030)
0.1 1.0 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.4 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 0.4 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.0 0.2 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.4 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.5 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.3 GO:0034227 tRNA thio-modification(GO:0034227)
0.0 0.2 GO:1903677 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.0 1.4 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.4 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.3 GO:0042997 negative regulation of low-density lipoprotein particle clearance(GO:0010989) negative regulation of Golgi to plasma membrane protein transport(GO:0042997) negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.0 0.2 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.0 0.2 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.0 0.6 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 1.0 GO:0044406 adhesion of symbiont to host(GO:0044406)
0.0 1.3 GO:0007131 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.0 1.6 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.6 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 1.6 GO:0060065 uterus development(GO:0060065)
0.0 0.5 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.3 GO:0015675 nickel cation transport(GO:0015675)
0.0 0.5 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
0.0 0.8 GO:0071501 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.1 GO:0002019 regulation of renal output by angiotensin(GO:0002019) smooth muscle adaptation(GO:0014805)
0.0 0.4 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 0.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.1 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.4 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 1.7 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.1 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350) nuclear retention of pre-mRNA at the site of transcription(GO:0071033)
0.0 0.2 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.4 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.2 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.1 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.0 0.1 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892)
0.0 0.7 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.0 0.4 GO:0070474 positive regulation of uterine smooth muscle contraction(GO:0070474)
0.0 1.2 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.8 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.2 GO:0072718 response to cisplatin(GO:0072718)
0.0 0.6 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.1 GO:0060160 negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.0 0.1 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0 0.2 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.5 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.5 GO:0045351 type I interferon biosynthetic process(GO:0045351)
0.0 0.6 GO:0090201 negative regulation of release of cytochrome c from mitochondria(GO:0090201)
0.0 0.2 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.3 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.3 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909)
0.0 0.1 GO:0006393 termination of mitochondrial transcription(GO:0006393)
0.0 0.3 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.1 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.0 0.4 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.7 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 0.2 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.4 GO:0097264 self proteolysis(GO:0097264)
0.0 0.2 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.0 0.2 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.7 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.4 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.0 0.4 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.4 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.0 0.9 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.1 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.3 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.0 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.1 GO:0051503 adenine nucleotide transport(GO:0051503)
0.0 0.7 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.3 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.1 GO:0006689 ganglioside catabolic process(GO:0006689) oligosaccharide catabolic process(GO:0009313)
0.0 0.2 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.1 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.7 GO:0043631 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.8 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.0 GO:0002355 detection of tumor cell(GO:0002355)
0.0 1.2 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.1 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.2 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.5 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.1 GO:0032252 secretory granule localization(GO:0032252)
0.0 0.1 GO:0036089 cleavage furrow formation(GO:0036089)
0.0 0.4 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.0 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.0 0.1 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.0 0.7 GO:0031338 regulation of vesicle fusion(GO:0031338)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0000814 ESCRT II complex(GO:0000814)
0.3 1.8 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.3 0.9 GO:0070992 translation initiation complex(GO:0070992)
0.3 0.8 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.2 2.3 GO:0030681 ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.2 0.6 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.2 0.8 GO:0071821 FANCM-MHF complex(GO:0071821)
0.2 1.1 GO:0097226 sperm mitochondrial sheath(GO:0097226)
0.2 0.4 GO:0005683 U7 snRNP(GO:0005683)
0.1 0.7 GO:1990131 Iml1 complex(GO:1990130) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.4 GO:0034455 t-UTP complex(GO:0034455)
0.1 0.6 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.1 1.0 GO:0042825 TAP complex(GO:0042825)
0.1 1.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 1.3 GO:0005687 U4 snRNP(GO:0005687)
0.1 0.5 GO:0034657 GID complex(GO:0034657)
0.1 0.3 GO:0016939 kinesin II complex(GO:0016939)
0.1 0.6 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 0.9 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 1.7 GO:0016580 Sin3 complex(GO:0016580)
0.1 1.0 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 0.9 GO:0000815 ESCRT III complex(GO:0000815)
0.1 2.0 GO:0005838 proteasome regulatory particle(GO:0005838)
0.1 0.7 GO:0070578 micro-ribonucleoprotein complex(GO:0035068) RISC-loading complex(GO:0070578)
0.1 0.8 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 0.8 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.1 0.3 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.1 0.5 GO:0097255 R2TP complex(GO:0097255)
0.1 0.4 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1 0.6 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 0.8 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.8 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.7 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.2 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.6 GO:0044754 autolysosome(GO:0044754)
0.0 0.4 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.2 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.5 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0098855 HCN channel complex(GO:0098855)
0.0 0.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.3 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.3 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.4 GO:0005869 dynactin complex(GO:0005869)
0.0 1.6 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.6 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.3 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.6 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.5 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.2 GO:0035859 Seh1-associated complex(GO:0035859) GATOR2 complex(GO:0061700)
0.0 0.5 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.5 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.5 GO:0031082 BLOC complex(GO:0031082)
0.0 0.2 GO:0070847 core mediator complex(GO:0070847)
0.0 5.0 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.4 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.0 GO:0002142 stereocilia ankle link complex(GO:0002142)
0.0 0.4 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.4 GO:0070938 contractile ring(GO:0070938)
0.0 0.5 GO:0001891 phagocytic cup(GO:0001891)
0.0 1.0 GO:0022627 small ribosomal subunit(GO:0015935) cytosolic small ribosomal subunit(GO:0022627)
0.0 0.1 GO:0005682 U5 snRNP(GO:0005682)
0.0 1.7 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.5 GO:0070069 cytochrome complex(GO:0070069)
0.0 0.3 GO:0051233 spindle midzone(GO:0051233)
0.0 1.2 GO:0032420 stereocilium(GO:0032420)
0.0 0.7 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 1.8 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.6 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.2 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.5 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0004454 ketohexokinase activity(GO:0004454)
0.4 1.5 GO:0047016 cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity(GO:0047016)
0.3 2.4 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.3 1.0 GO:0046980 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
0.3 0.9 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.3 1.8 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.3 1.6 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.2 1.2 GO:0030984 kininogen binding(GO:0030984)
0.2 0.9 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.2 0.7 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.2 1.1 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761)
0.2 1.4 GO:0004526 ribonuclease P activity(GO:0004526)
0.2 0.6 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.2 0.6 GO:0051747 cytosine C-5 DNA demethylase activity(GO:0051747)
0.2 0.6 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.2 0.4 GO:0071209 U7 snRNA binding(GO:0071209)
0.2 0.5 GO:0035539 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.2 0.5 GO:0004686 elongation factor-2 kinase activity(GO:0004686)
0.2 0.5 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.2 1.1 GO:0002135 CTP binding(GO:0002135)
0.1 0.4 GO:0036461 BLOC-2 complex binding(GO:0036461)
0.1 0.5 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 0.5 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 0.5 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.1 0.8 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 0.9 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.1 0.6 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.8 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.4 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.1 0.4 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.1 1.3 GO:1990446 U1 snRNP binding(GO:1990446)
0.1 2.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.8 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.1 0.6 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.1 0.2 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.1 0.4 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 0.5 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 1.0 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.1 0.6 GO:0000150 recombinase activity(GO:0000150)
0.1 0.7 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.4 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.5 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 0.2 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.1 0.3 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.1 0.7 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.1 0.3 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 0.4 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.4 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.2 GO:0008802 betaine-aldehyde dehydrogenase activity(GO:0008802)
0.1 0.7 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 0.2 GO:0031753 endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755)
0.1 0.5 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 0.3 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.4 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 3.5 GO:0019843 rRNA binding(GO:0019843)
0.0 0.1 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.0 0.6 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.4 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.4 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.3 GO:0015099 nickel cation transmembrane transporter activity(GO:0015099)
0.0 0.6 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013)
0.0 1.7 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.2 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.7 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.2 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.2 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.4 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.4 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.2 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.9 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 1.8 GO:0043022 ribosome binding(GO:0043022)
0.0 1.4 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.3 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.3 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.6 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.4 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 1.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0052794 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.2 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.7 GO:0005112 Notch binding(GO:0005112)
0.0 0.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.5 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.4 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.5 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.1 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.8 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 1.2 GO:0003724 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.3 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.3 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.6 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.5 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.7 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.0 GO:0097677 STAT family protein binding(GO:0097677)
0.0 0.8 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.9 GO:0044390 ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 0.2 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.8 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.1 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.1 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.0 GO:0047936 glucose 1-dehydrogenase [NAD(P)] activity(GO:0047936)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.5 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.2 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.2 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 2.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.1 GO:0004673 phosphorelay sensor kinase activity(GO:0000155) protein histidine kinase activity(GO:0004673)
0.0 0.0 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 0.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0070287 ferritin receptor activity(GO:0070287)
0.0 0.8 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 1.3 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.6 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.8 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 2.1 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 2.0 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 1.2 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.5 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 2.6 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 2.1 PID E2F PATHWAY E2F transcription factor network
0.0 1.0 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.7 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 1.0 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.5 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.5 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.4 PID AURORA A PATHWAY Aurora A signaling
0.0 0.4 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.8 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.1 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 1.6 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 1.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 1.8 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 2.5 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 1.2 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 1.7 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 3.6 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 0.7 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.2 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 0.7 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.8 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.5 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.9 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.6 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 1.1 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 1.1 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.3 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 1.2 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 1.3 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.8 REACTOME KINESINS Genes involved in Kinesins
0.0 1.2 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.4 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.0 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.8 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.6 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.3 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.9 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.2 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events