avrg: GFI1 WT vs 36n/n vs KD

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
Rest Links Ensembl NCBI MGI UniProt	ENSMUSG00000029249.16	RE1-silencing transcription factor

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Rest	mm39_v1_chr5_+_77414031_77414056	0.97	6.9e-03	Click!

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chrX_-_72913410 Show fit	3.99	ENSMUST00000066576.12 ENSMUST00000114430.8	L1cam Links Ensembl NCBI MGI UniProt Show fit	L1 cell adhesion molecule
chr6_-_121450547 Show fit	3.01	ENSMUST00000046373.8 ENSMUST00000151397.3	Iqsec3 Links Ensembl NCBI MGI UniProt Show fit	IQ motif and Sec7 domain 3
chrX_-_20787150 Show fit	1.81	ENSMUST00000081893.7 ENSMUST00000115345.8	Syn1 Links Ensembl NCBI MGI UniProt Show fit	synapsin I
chr1_+_159351337 Show fit	1.63	ENSMUST00000192069.6	Tnr Links Ensembl NCBI MGI UniProt Show fit	tenascin R
chr7_+_6459167 Show fit	1.56	ENSMUST00000214301.3	Olfr1336 Links Ensembl NCBI MGI UniProt Show fit	olfactory receptor 1336
chr6_+_113259262 Show fit	1.39	ENSMUST00000041203.6	Cpne9 Links Ensembl NCBI MGI UniProt Show fit	copine family member IX
chr5_-_121148143 Show fit	1.38	ENSMUST00000202406.4 ENSMUST00000200792.2	Rph3a Links Ensembl NCBI MGI UniProt Show fit	rabphilin 3A
chr10_-_128505096 Show fit	1.29	ENSMUST00000238610.2 ENSMUST00000238712.2	Ikzf4 Links Ensembl NCBI MGI UniProt Show fit	IKAROS family zinc finger 4
chr5_-_121147593 Show fit	1.21	ENSMUST00000079204.9	Rph3a Links Ensembl NCBI MGI UniProt Show fit	rabphilin 3A
chr6_+_117145496 Show fit	1.05	ENSMUST00000112866.8 ENSMUST00000112871.8 ENSMUST00000073043.5	Cxcl12 Links Ensembl NCBI MGI UniProt Show fit	chemokine (C-X-C motif) ligand 12
chr9_+_121946404 Show fit	1.02	ENSMUST00000134949.8	Snrk Links Ensembl NCBI MGI UniProt Show fit	SNF related kinase
chr2_+_22512195 Show fit	0.99	ENSMUST00000028123.4	Gad2 Links Ensembl NCBI MGI UniProt Show fit	glutamic acid decarboxylase 2
chr13_+_54519161 Show fit	0.97	ENSMUST00000026985.9	Cplx2 Links Ensembl NCBI MGI UniProt Show fit	complexin 2
chr2_-_37007795 Show fit	0.95	ENSMUST00000213817.2 ENSMUST00000215927.2	Olfr362 Links Ensembl NCBI MGI UniProt Show fit	olfactory receptor 362
chr16_-_90808196 Show fit	0.80	ENSMUST00000121759.8	Synj1 Links Ensembl NCBI MGI UniProt Show fit	synaptojanin 1
chr13_-_105191403 Show fit	0.70	ENSMUST00000063551.7	Rgs7bp Links Ensembl NCBI MGI UniProt Show fit	regulator of G-protein signalling 7 binding protein
chr11_+_69805005 Show fit	0.60	ENSMUST00000057884.6	Gps2 Links Ensembl NCBI MGI UniProt Show fit	G protein pathway suppressor 2
chr7_+_49559859 Show fit	0.49	ENSMUST00000056442.12	Slc6a5 Links Ensembl NCBI MGI UniProt Show fit	solute carrier family 6 (neurotransmitter transporter, glycine), member 5
chr19_+_42244143 Show fit	0.47	ENSMUST00000087123.6	Golga7b Links Ensembl NCBI MGI UniProt Show fit	golgi autoantigen, golgin subfamily a, 7B
chr4_+_152243324 Show fit	0.46	ENSMUST00000030782.2	Hes2 Links Ensembl NCBI MGI UniProt Show fit	hes family bHLH transcription factor 2
chr5_+_117258185 Show fit	0.46	ENSMUST00000111978.8	Taok3 Links Ensembl NCBI MGI UniProt Show fit	TAO kinase 3
chr3_+_94385602 Show fit	0.46	ENSMUST00000199884.5 ENSMUST00000198316.5 ENSMUST00000197558.5	Celf3 Links Ensembl NCBI MGI UniProt Show fit	CUGBP, Elav-like family member 3
chr17_-_23959334 Show fit	0.39	ENSMUST00000024702.5	Paqr4 Links Ensembl NCBI MGI UniProt Show fit	progestin and adipoQ receptor family member IV
chr12_-_70394074 Show fit	0.38	ENSMUST00000223160.2 ENSMUST00000222316.2 ENSMUST00000167755.3 ENSMUST00000110520.10 ENSMUST00000110522.10 ENSMUST00000221041.2 ENSMUST00000222603.3	Trim9 Links Ensembl NCBI MGI UniProt Show fit	tripartite motif-containing 9
chr3_-_89671888 Show fit	0.37	ENSMUST00000200558.5 ENSMUST00000029562.5	Chrnb2 Links Ensembl NCBI MGI UniProt Show fit	cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)
chr10_+_6738809 Show fit	0.37	ENSMUST00000105602.8 ENSMUST00000078634.12 ENSMUST00000000783.13 ENSMUST00000092731.11 ENSMUST00000154906.8 ENSMUST00000105605.8 ENSMUST00000135502.8 ENSMUST00000052751.14 ENSMUST00000105611.8 ENSMUST00000105603.2 ENSMUST00000105604.8	Oprm1 Links Ensembl NCBI MGI UniProt Show fit	opioid receptor, mu 1
chr3_+_94385661 Show fit	0.34	ENSMUST00000200342.5	Celf3 Links Ensembl NCBI MGI UniProt Show fit	CUGBP, Elav-like family member 3
chr2_-_92231598 Show fit	0.30	ENSMUST00000050312.3	Mapk8ip1 Links Ensembl NCBI MGI UniProt Show fit	mitogen-activated protein kinase 8 interacting protein 1
chr12_-_113680723 Show fit	0.29	ENSMUST00000179657.2	Ighv2-6 Links Ensembl NCBI MGI UniProt Show fit	immunoglobulin heavy variable 2-6
chr8_-_123302187 Show fit	0.28	ENSMUST00000213062.2	Aprt Links Ensembl NCBI MGI UniProt Show fit	adenine phosphoribosyl transferase
chr3_-_80710097 Show fit	0.25	ENSMUST00000075316.10 ENSMUST00000107745.8	Gria2 Links Ensembl NCBI MGI UniProt Show fit	glutamate receptor, ionotropic, AMPA2 (alpha 2)
chr9_+_59485475 Show fit	0.24	ENSMUST00000118549.8 ENSMUST00000034840.10	Celf6 Links Ensembl NCBI MGI UniProt Show fit	CUGBP, Elav-like family member 6
chr9_+_40180569 Show fit	0.23	ENSMUST00000176185.8	Scn3b Links Ensembl NCBI MGI UniProt Show fit	sodium channel, voltage-gated, type III, beta
chr9_+_40180726 Show fit	0.23	ENSMUST00000171835.9	Scn3b Links Ensembl NCBI MGI UniProt Show fit	sodium channel, voltage-gated, type III, beta
chr2_-_28806639 Show fit	0.21	ENSMUST00000113847.3	Barhl1 Links Ensembl NCBI MGI UniProt Show fit	BarH like homeobox 1
chr9_+_40180497 Show fit	0.21	ENSMUST00000049941.12	Scn3b Links Ensembl NCBI MGI UniProt Show fit	sodium channel, voltage-gated, type III, beta
chr8_+_85673616 Show fit	0.17	ENSMUST00000067472.14 ENSMUST00000109740.9	Rtbdn Links Ensembl NCBI MGI UniProt Show fit	retbindin
chr4_-_129015027 Show fit	0.16	ENSMUST00000030572.10	Hpca Links Ensembl NCBI MGI UniProt Show fit	hippocalcin
chr10_-_115423644 Show fit	0.16	ENSMUST00000020350.15	Lgr5 Links Ensembl NCBI MGI UniProt Show fit	leucine rich repeat containing G protein coupled receptor 5
chr12_+_113103817 Show fit	0.14	ENSMUST00000084882.9	Crip2 Links Ensembl NCBI MGI UniProt Show fit	cysteine rich protein 2
chr15_-_76606361 Show fit	0.14	ENSMUST00000049956.5	Lrrc24 Links Ensembl NCBI MGI UniProt Show fit	leucine rich repeat containing 24
chr17_+_28794615 Show fit	0.12	ENSMUST00000232862.2 ENSMUST00000080780.8	Lhfpl5 Links Ensembl NCBI MGI UniProt Show fit	lipoma HMGIC fusion partner-like 5
chr5_+_137059127 Show fit	0.12	ENSMUST00000041543.9 ENSMUST00000186451.2	Vgf Links Ensembl NCBI MGI UniProt Show fit	VGF nerve growth factor inducible
chr5_+_104194735 Show fit	0.11	ENSMUST00000031250.14	Nudt9 Links Ensembl NCBI MGI UniProt Show fit	nudix (nucleoside diphosphate linked moiety X)-type motif 9
chr12_+_102521225 Show fit	0.11	ENSMUST00000021610.7	Chga Links Ensembl NCBI MGI UniProt Show fit	chromogranin A
chr17_+_28794727 Show fit	0.10	ENSMUST00000232974.2	Lhfpl5 Links Ensembl NCBI MGI UniProt Show fit	lipoma HMGIC fusion partner-like 5
chr4_+_12906838 Show fit	0.07	ENSMUST00000143186.8 ENSMUST00000183345.2	Triqk Links Ensembl NCBI MGI UniProt Show fit	triple QxxK/R motif containing
chr1_-_175319842 Show fit	0.06	ENSMUST00000195324.6 ENSMUST00000192227.6 ENSMUST00000194555.6	Rgs7 Links Ensembl NCBI MGI UniProt Show fit	regulator of G protein signaling 7
chr1_-_84673903 Show fit	0.06	ENSMUST00000049126.13	Dner Links Ensembl NCBI MGI UniProt Show fit	delta/notch-like EGF repeat containing
chr5_+_28047147 Show fit	0.06	ENSMUST00000036227.7	Htr5a Links Ensembl NCBI MGI UniProt Show fit	5-hydroxytryptamine (serotonin) receptor 5A
chr7_-_3619132 Show fit	0.06	ENSMUST00000039507.15 ENSMUST00000108645.8 ENSMUST00000148012.2	Oscar Links Ensembl NCBI MGI UniProt Show fit	osteoclast associated receptor
chr1_-_192718064 Show fit	0.03	ENSMUST00000215093.2 ENSMUST00000195354.6	Syt14 Links Ensembl NCBI MGI UniProt Show fit	synaptotagmin XIV
chr9_+_40712562 Show fit	0.03	ENSMUST00000117557.8	Hspa8 Links Ensembl NCBI MGI UniProt Show fit	heat shock protein 8
chrX_+_7504913 Show fit	0.03	ENSMUST00000128890.2	Syp Links Ensembl NCBI MGI UniProt Show fit	synaptophysin
chr8_-_105036739 Show fit	0.03	ENSMUST00000159039.2	Cmtm1 Links Ensembl NCBI MGI UniProt Show fit	CKLF-like MARVEL transmembrane domain containing 1
chr8_-_105036664 Show fit	0.03	ENSMUST00000160596.8 ENSMUST00000164175.2	Cmtm1 Links Ensembl NCBI MGI UniProt Show fit	CKLF-like MARVEL transmembrane domain containing 1
chr2_+_151985467 Show fit	0.03	ENSMUST00000089112.6	Tcf15 Links Ensembl NCBI MGI UniProt Show fit	transcription factor 15
chr11_+_77821626 Show fit	0.02	ENSMUST00000093995.10 ENSMUST00000000646.14	Sez6 Links Ensembl NCBI MGI UniProt Show fit	seizure related gene 6
chr5_-_31296173 Show fit	0.02	ENSMUST00000043475.7 ENSMUST00000201184.2	Ucn Links Ensembl NCBI MGI UniProt Show fit	urocortin
chr9_+_40785277 Show fit	0.02	ENSMUST00000067375.5	Bsx Links Ensembl NCBI MGI UniProt Show fit	brain specific homeobox
chr7_+_28222261 Show fit	0.02	ENSMUST00000078364.4	Ifnl3 Links Ensembl NCBI MGI UniProt Show fit	interferon lambda 3
chr2_-_180956293 Show fit	0.02	ENSMUST00000103045.4	Stmn3 Links Ensembl NCBI MGI UniProt Show fit	stathmin-like 3
chr7_-_6489812 Show fit	0.02	ENSMUST00000086318.5 ENSMUST00000209866.4	Olfr5 Links Ensembl NCBI MGI UniProt Show fit	olfactory receptor 5
chr2_+_132623198 Show fit	0.02	ENSMUST00000028826.4	Chgb Links Ensembl NCBI MGI UniProt Show fit	chromogranin B
chr2_-_122144125 Show fit	0.01	ENSMUST00000147788.8 ENSMUST00000154412.2 ENSMUST00000110537.8 ENSMUST00000148417.8	Duoxa1 Links Ensembl NCBI MGI UniProt Show fit	dual oxidase maturation factor 1
chr12_-_112477536 Show fit	0.01	ENSMUST00000066791.7	Tmem179 Links Ensembl NCBI MGI UniProt Show fit	transmembrane protein 179
chr5_-_116729870 Show fit	0.01	ENSMUST00000076124.7	Srrm4 Links Ensembl NCBI MGI UniProt Show fit	serine/arginine repetitive matrix 4
chr2_-_27032441 Show fit	0.01	ENSMUST00000151224.3	Fam163b Links Ensembl NCBI MGI UniProt Show fit	family with sequence similarity 163, member B
chr4_+_148070245 Show fit	0.01	ENSMUST00000103231.5	Nppb Links Ensembl NCBI MGI UniProt Show fit	natriuretic peptide type B
chr4_-_49681954 Show fit	0.01	ENSMUST00000029991.3	Ppp3r2 Links Ensembl NCBI MGI UniProt Show fit	protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type II)
chr2_-_26098293 Show fit	0.01	ENSMUST00000054099.16	Lhx3 Links Ensembl NCBI MGI UniProt Show fit	LIM homeobox protein 3
chr7_-_81143412 Show fit	0.01	ENSMUST00000238438.2 ENSMUST00000238711.2	Ap3b2 Links Ensembl NCBI MGI UniProt Show fit	adaptor-related protein complex 3, beta 2 subunit
chr11_+_74510413 Show fit	0.01	ENSMUST00000100866.3	Ccdc92b Links Ensembl NCBI MGI UniProt Show fit	coiled-coil domain containing 92B
chr9_-_121620150 Show fit	0.01	ENSMUST00000215910.2 ENSMUST00000215477.2 ENSMUST00000163981.3	Hhatl Links Ensembl NCBI MGI UniProt Show fit	hedgehog acyltransferase-like
chr2_-_179746227 Show fit	0.01	ENSMUST00000056480.10	Hrh3 Links Ensembl NCBI MGI UniProt Show fit	histamine receptor H3
chr7_-_79244677 Show fit	0.00	ENSMUST00000172788.3	Rhcg Links Ensembl NCBI MGI UniProt Show fit	Rhesus blood group-associated C glycoprotein
chr7_-_28209880 Show fit	0.00	ENSMUST00000081684.3	Ifnl2 Links Ensembl NCBI MGI UniProt Show fit	interferon lambda 2
chr11_-_87811788 Show fit	0.00	ENSMUST00000216461.2 ENSMUST00000217112.2	Olfr464 Links Ensembl NCBI MGI UniProt Show fit	olfactory receptor 464

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Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.6	GO:0048686	regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.3	4.0	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.3	0.8	GO:0098884	postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.3	1.1	GO:1903237	negative regulation of leukocyte tethering or rolling(GO:1903237)
0.2	1.0	GO:0006538	glutamate catabolic process(GO:0006538)
0.1	0.4	GO:0035544	negative regulation of SNARE complex assembly(GO:0035544)
0.1	0.5	GO:0036233	glycine import(GO:0036233)
0.1	0.4	GO:0071317	cellular response to isoquinoline alkaloid(GO:0071317)
0.1	0.4	GO:0060084	synaptic transmission involved in micturition(GO:0060084)
0.1	3.0	GO:0032012	ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1	1.8	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1	0.3	GO:0006168	adenine salvage(GO:0006168) purine nucleobase salvage(GO:0043096) adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.1	1.0	GO:0031915	positive regulation of synaptic plasticity(GO:0031915)
0.1	0.7	GO:0060373	regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.1	2.6	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1	0.2	GO:0030827	negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
0.0	1.4	GO:1903861	positive regulation of dendrite extension(GO:1903861)
0.0	0.3	GO:0007258	JUN phosphorylation(GO:0007258)
0.0	0.5	GO:0018230	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0	0.1	GO:1900738	positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.0	0.8	GO:0030575	nuclear body organization(GO:0030575)
0.0	1.1	GO:0046329	negative regulation of JNK cascade(GO:0046329)
0.0	0.0	GO:0071211	protein targeting to vacuole involved in autophagy(GO:0071211)
0.0	0.1	GO:0007198	adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0	0.2	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.6	GO:0072534	perineuronal net(GO:0072534)
0.2	4.3	GO:0044294	dendritic growth cone(GO:0044294)
0.2	1.0	GO:0070033	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.1	3.8	GO:0060077	inhibitory synapse(GO:0060077)
0.1	4.6	GO:0030672	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0	0.2	GO:0033165	interphotoreceptor matrix(GO:0033165)
0.0	0.5	GO:0002178	palmitoyltransferase complex(GO:0002178)
0.0	0.8	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.0	0.7	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.0	0.1	GO:0042583	chromaffin granule(GO:0042583)
0.0	0.4	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.2	GO:0044327	dendritic spine head(GO:0044327)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	4.0	GO:0033691	sialic acid binding(GO:0033691)
0.2	2.6	GO:0042301	phosphate ion binding(GO:0042301) inositol 1,4,5 trisphosphate binding(GO:0070679)
0.2	0.8	GO:0043812	phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.1	1.0	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.1	1.1	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.1	0.3	GO:0003999	adenine binding(GO:0002055) adenine phosphoribosyltransferase activity(GO:0003999)
0.1	1.6	GO:0046625	sphingolipid binding(GO:0046625)
0.1	0.7	GO:0086006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1	3.0	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1	0.8	GO:0097322	7SK snRNA binding(GO:0097322)
0.1	0.4	GO:0004985	melanocortin receptor activity(GO:0004977) opioid receptor activity(GO:0004985)
0.0	0.2	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.0	0.5	GO:0015187	glycine transmembrane transporter activity(GO:0015187)
0.0	1.0	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	0.4	GO:0042166	acetylcholine binding(GO:0042166)
0.0	1.3	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	0.3	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.5	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	1.7	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.0	0.5	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	4.0	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.0	1.1	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	0.5	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	0.8	PID EPHB FWD PATHWAY	EPHB forward signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.8	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.1	4.6	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.1	1.0	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	0.5	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.4	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0	1.1	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.8	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.3	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.2	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors