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avrg: GFI1 WT vs 36n/n vs KD

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Results for Rfx3_Rfx1_Rfx4

Z-value: 1.31

Motif logo

Transcription factors associated with Rfx3_Rfx1_Rfx4

Gene Symbol Gene ID Gene Info
ENSMUSG00000040929.18 regulatory factor X, 3 (influences HLA class II expression)
ENSMUSG00000031706.8 regulatory factor X, 1 (influences HLA class II expression)
ENSMUSG00000020037.16 regulatory factor X, 4 (influences HLA class II expression)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Rfx4mm39_v1_chr10_+_84674008_84674016-0.838.0e-02Click!
Rfx1mm39_v1_chr8_+_84793453_84793511-0.771.3e-01Click!
Rfx3mm39_v1_chr19_-_27988534_27988581-0.761.3e-01Click!

Activity profile of Rfx3_Rfx1_Rfx4 motif

Sorted Z-values of Rfx3_Rfx1_Rfx4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_43031370 1.52 ENSMUST00000138030.2
ENSMUST00000136326.8
stomatin (Epb7.2)-like 2
chr11_+_87651359 0.86 ENSMUST00000039627.12
ENSMUST00000100644.10
TSPO associated protein 1
chr4_-_94940425 0.84 ENSMUST00000107094.2
jun proto-oncogene
chr5_-_137529251 0.63 ENSMUST00000132525.8
guanine nucleotide binding protein (G protein), beta 2
chr10_+_61431271 0.62 ENSMUST00000020287.8
neuropeptide FF receptor 1
chr5_-_137074880 0.61 ENSMUST00000144303.2
ENSMUST00000111080.8
adaptor protein complex AP-1, sigma 1
chr17_-_35055843 0.60 ENSMUST00000077477.12
serine/threonine kinase 19
chr2_-_91274967 0.55 ENSMUST00000064652.14
ENSMUST00000102594.11
ENSMUST00000094835.9
RIKEN cDNA 1110051M20 gene
chr15_-_78947038 0.53 ENSMUST00000151889.8
ENSMUST00000040676.11
ankyrin repeat domain 54
chr14_+_51193449 0.52 ENSMUST00000095925.5
purine-nucleoside phosphorylase 2
chr4_-_133694607 0.52 ENSMUST00000105893.8
high mobility group nucleosomal binding domain 2
chr2_+_80145805 0.52 ENSMUST00000028392.8
DnaJ heat shock protein family (Hsp40) member C10
chr9_+_107926502 0.47 ENSMUST00000047947.9
GDP-mannose pyrophosphorylase B
chr5_-_137529465 0.47 ENSMUST00000150063.9
guanine nucleotide binding protein (G protein), beta 2
chr7_+_18910340 0.45 ENSMUST00000117338.8
echinoderm microtubule associated protein like 2
chr4_-_129556234 0.45 ENSMUST00000003828.11
karyopherin (importin) alpha 6
chr7_+_18883647 0.44 ENSMUST00000049294.4
small nuclear ribonucleoprotein D2
chr6_+_88061464 0.43 ENSMUST00000032143.8
ribophorin I
chr3_-_146476331 0.43 ENSMUST00000106138.8
protein kinase, cAMP dependent, catalytic, beta
chr2_+_29678248 0.43 ENSMUST00000028137.10
ENSMUST00000148791.2
coenzyme Q4
chr8_-_123939480 0.43 ENSMUST00000000759.9
charged multivesicular body protein 1A
chr3_-_146475974 0.42 ENSMUST00000106137.8
protein kinase, cAMP dependent, catalytic, beta
chr17_-_46558894 0.42 ENSMUST00000142706.9
ENSMUST00000173349.8
ENSMUST00000087026.13
polymerase (RNA) I polypeptide C
chr3_+_103875574 0.42 ENSMUST00000063717.14
ENSMUST00000055425.15
ENSMUST00000123611.8
ENSMUST00000090685.11
putative homeodomain transcription factor 1
chr9_-_60594742 0.42 ENSMUST00000114032.8
ENSMUST00000166168.8
ENSMUST00000132366.2
leucine rich repeat containing 49
chr2_-_29938841 0.41 ENSMUST00000113711.3
dynein 2 intermediate chain 2
chr17_-_80514725 0.40 ENSMUST00000234696.2
ENSMUST00000235069.2
ENSMUST00000063417.11
serine and arginine-rich splicing factor 7
chr5_+_137756407 0.40 ENSMUST00000141733.8
ENSMUST00000110985.2
TSC22 domain family, member 4
chr10_-_116899664 0.40 ENSMUST00000218719.2
ENSMUST00000219573.2
ENSMUST00000047672.9
chaperonin containing Tcp1, subunit 2 (beta)
chr7_-_4687916 0.40 ENSMUST00000206306.2
ENSMUST00000205952.2
ENSMUST00000079970.6
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr7_-_45480200 0.40 ENSMUST00000107723.9
ENSMUST00000131384.3
glutamate-rich WD repeat containing 1
chr8_-_65186565 0.40 ENSMUST00000141021.2
methylsterol monoxygenase 1
chr15_+_79543397 0.40 ENSMUST00000023064.9
chibby family member 1, beta catenin antagonist
chr17_+_35055962 0.39 ENSMUST00000173874.8
ENSMUST00000180043.8
ENSMUST00000046244.15
decapping exoribonuclease
chr2_-_127630769 0.39 ENSMUST00000028857.14
ENSMUST00000110357.2
nephronophthisis 1 (juvenile) homolog (human)
chr12_+_82216193 0.38 ENSMUST00000166429.9
ENSMUST00000220963.2
signal-induced proliferation-associated 1 like 1
chr19_+_45549009 0.38 ENSMUST00000047057.9
predicted gene 17018
chr5_-_115438971 0.38 ENSMUST00000112090.2
dynein light chain LC8-type 1
chr5_-_41865461 0.38 ENSMUST00000201422.4
RAB28, member RAS oncogene family
chr1_-_156501860 0.38 ENSMUST00000188964.7
ENSMUST00000190607.2
ENSMUST00000079625.11
torsin family 3, member A
chr11_-_119190830 0.37 ENSMUST00000106253.2
eukaryotic translation initiation factor 4A3
chr14_+_51181956 0.37 ENSMUST00000178092.2
ENSMUST00000227052.2
purine-nucleoside phosphorylase
predicted gene, 49342
chr5_-_41865477 0.37 ENSMUST00000031011.12
ENSMUST00000202913.2
RAB28, member RAS oncogene family
chr10_+_80905869 0.36 ENSMUST00000005057.7
thimet oligopeptidase 1
chr17_-_26014613 0.36 ENSMUST00000235889.2
predicted gene, 50367
chr9_-_60595401 0.36 ENSMUST00000114034.9
ENSMUST00000065603.12
leucine rich repeat containing 49
chr7_+_79836581 0.36 ENSMUST00000032754.9
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr12_-_83609217 0.36 ENSMUST00000222448.2
zinc finger, FYVE domain containing 1
chr16_-_91525485 0.35 ENSMUST00000231499.2
ENSMUST00000141664.9
ENSMUST00000123751.2
ENSMUST00000122254.8
ENSMUST00000114023.3
crystallin, zeta (quinone reductase)-like 1
chr15_+_81548090 0.35 ENSMUST00000023029.15
ENSMUST00000174229.8
ENSMUST00000172748.8
L3MBTL2 polycomb repressive complex 1 subunit
chr12_+_84408803 0.34 ENSMUST00000110278.8
ENSMUST00000145522.2
coenzyme Q6 monooxygenase
chr7_-_12788592 0.34 ENSMUST00000182515.8
ENSMUST00000069289.15
myeloid zinc finger 1
chr1_-_192946359 0.34 ENSMUST00000161737.8
hydroxysteroid 11-beta dehydrogenase 1
chr14_-_30723549 0.33 ENSMUST00000226782.2
ENSMUST00000186131.7
ENSMUST00000228767.2
signal peptidase complex subunit 1 homolog (S. cerevisiae)
chr7_-_12788441 0.33 ENSMUST00000182087.2
myeloid zinc finger 1
chr7_-_118304930 0.33 ENSMUST00000207323.2
ENSMUST00000038791.15
glycerophosphodiester phosphodiesterase 1
chr12_+_84408742 0.33 ENSMUST00000021661.13
coenzyme Q6 monooxygenase
chr2_+_21210527 0.32 ENSMUST00000054591.10
ENSMUST00000102952.8
ENSMUST00000138965.8
ENSMUST00000138914.8
ENSMUST00000102951.2
threonine synthase-like 1 (bacterial)
chr19_-_45548942 0.32 ENSMUST00000026239.7
polymerase (DNA directed), lambda
chr17_+_26048010 0.32 ENSMUST00000026832.14
jumonji domain containing 8
chr2_-_90735171 0.32 ENSMUST00000005647.4
NADH:ubiquinone oxidoreductase core subunit S3
chr5_-_124616393 0.32 ENSMUST00000031347.8
Rab interacting lysosomal protein-like 2
chr10_-_79710067 0.31 ENSMUST00000166023.2
ENSMUST00000167707.2
ENSMUST00000165601.8
phospholipid phosphatase related 3
chr15_+_100659622 0.31 ENSMUST00000023776.13
solute carrier family 4 (anion exchanger), member 8
chr12_-_86773160 0.31 ENSMUST00000021682.9
angel homolog 1
chr6_+_83162928 0.31 ENSMUST00000113907.2
dynactin 1
chr1_+_191553556 0.31 ENSMUST00000027931.8
NIMA (never in mitosis gene a)-related expressed kinase 2
chr2_-_134486039 0.31 ENSMUST00000038228.11
thioredoxin-related transmembrane protein 4
chr11_+_68961599 0.30 ENSMUST00000075980.12
ENSMUST00000094081.5
transmembrane protein 107
chr19_-_10533088 0.30 ENSMUST00000059582.9
ENSMUST00000154383.2
transmembrane protein 216
chr11_-_119190896 0.30 ENSMUST00000026667.15
eukaryotic translation initiation factor 4A3
chr7_+_140462343 0.30 ENSMUST00000163610.9
ENSMUST00000164681.8
proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
chr1_-_59276252 0.29 ENSMUST00000163058.2
ENSMUST00000160945.2
ENSMUST00000027178.13
alsin Rho guanine nucleotide exchange factor
chr10_+_126899468 0.29 ENSMUST00000120226.8
ENSMUST00000133115.8
cyclin-dependent kinase 4
chr10_-_75673175 0.29 ENSMUST00000220440.2
glutathione S-transferase, theta 2
chr6_-_113717689 0.29 ENSMUST00000032440.6
SEC13 homolog, nuclear pore and COPII coat complex component
chr7_-_16761732 0.27 ENSMUST00000142597.2
protein phosphatase 5, catalytic subunit
chr7_+_127187910 0.27 ENSMUST00000205694.2
ENSMUST00000033088.8
ENSMUST00000206914.2
ring finger protein 40
chr14_-_55880980 0.26 ENSMUST00000132338.8
transmembrane 9 superfamily member 1
chr15_+_84926909 0.26 ENSMUST00000229203.2
family with sequence similarity 118, member A
chr16_+_3726665 0.26 ENSMUST00000145150.9
ENSMUST00000040881.14
ENSMUST00000124849.2
clusterin associated protein 1
chrX_-_7999009 0.26 ENSMUST00000130832.8
ENSMUST00000033506.13
ENSMUST00000115623.8
ENSMUST00000153839.2
WD repeat domain 13
chr1_-_59158902 0.26 ENSMUST00000087475.11
transmembrane protein 237
chr16_+_32238520 0.26 ENSMUST00000014220.15
ENSMUST00000080316.8
dynein light chain Tctex-type 2B
chr9_+_65368207 0.26 ENSMUST00000034955.8
ENSMUST00000213957.2
SPG21, maspardin
chr13_-_107073415 0.26 ENSMUST00000080856.14
importin 11
chr7_+_140461860 0.26 ENSMUST00000026560.14
proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
chrX_+_47712676 0.26 ENSMUST00000177710.2
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr1_+_75498162 0.26 ENSMUST00000027414.16
ENSMUST00000113553.2
serine/threonine kinase 11 interacting protein
chr14_-_30723292 0.25 ENSMUST00000228736.2
ENSMUST00000226374.2
signal peptidase complex subunit 1 homolog (S. cerevisiae)
chr7_-_133378410 0.25 ENSMUST00000130182.2
ENSMUST00000106139.8
DEAH (Asp-Glu-Ala-His) box polypeptide 32
chr3_-_105867415 0.25 ENSMUST00000118209.8
ATP synthase peripheral stalk-membrane subunit b
chr8_+_110944575 0.25 ENSMUST00000056972.6
cap methyltransferase 2
chr5_-_114961501 0.24 ENSMUST00000100850.6
RIKEN cDNA 1500011B03 gene
chr10_-_79710468 0.24 ENSMUST00000092325.11
phospholipid phosphatase related 3
chr8_-_84059048 0.24 ENSMUST00000177594.8
ENSMUST00000053902.4
ELMO/CED-12 domain containing 2
chr4_-_133694543 0.24 ENSMUST00000123234.8
high mobility group nucleosomal binding domain 2
chr2_+_166634445 0.24 ENSMUST00000065753.2
transformation related protein 53 regulating kinase B
chr16_+_49519561 0.24 ENSMUST00000046777.11
ENSMUST00000142682.9
intraflagellar transport 57
chr4_-_116982804 0.23 ENSMUST00000183310.2
BTB (POZ) domain containing 19
chr11_+_70021155 0.23 ENSMUST00000041550.12
ENSMUST00000165951.8
macrophage galactose N-acetyl-galactosamine specific lectin 2
chr5_-_149559636 0.23 ENSMUST00000201452.4
heat shock 105kDa/110kDa protein 1
chr3_-_89152320 0.23 ENSMUST00000107464.8
ENSMUST00000090924.13
tripartite motif-containing 46
chr7_-_79882228 0.23 ENSMUST00000123279.8
calcium and integrin binding 1 (calmyrin)
chr12_-_110855521 0.23 ENSMUST00000220607.2
ENSMUST00000221182.2
ENSMUST00000222457.2
ENSMUST00000221102.2
ENSMUST00000043716.9
cyclin-dependent kinase 2 interacting protein
chr1_+_75213044 0.23 ENSMUST00000188931.7
DnaJ heat shock protein family (Hsp40) member B2
chr9_-_24414423 0.23 ENSMUST00000142064.8
ENSMUST00000170356.2
dpy-19-like 1 (C. elegans)
chr11_-_87249837 0.23 ENSMUST00000055438.5
protein phosphatase 1E (PP2C domain containing)
chr12_+_72583114 0.23 ENSMUST00000044352.8
pecanex homolog 4
chr19_-_10533562 0.23 ENSMUST00000025569.9
transmembrane protein 216
chr17_+_36290743 0.23 ENSMUST00000087200.4
guanine nucleotide binding protein-like 1
chr8_-_79547707 0.23 ENSMUST00000130325.8
ENSMUST00000051867.7
LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated
chr4_-_41314877 0.22 ENSMUST00000030145.9
DDB1 and CUL4 associated factor 12
chr5_-_149559667 0.22 ENSMUST00000074846.14
heat shock 105kDa/110kDa protein 1
chr7_-_109092834 0.22 ENSMUST00000106739.8
tripartite motif-containing 66
chr14_-_70391260 0.22 ENSMUST00000035612.7
cell cycle activator and apoptosis regulator 2
chr9_+_20563386 0.22 ENSMUST00000034689.8
protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1
chr2_+_90735077 0.22 ENSMUST00000111464.8
ENSMUST00000090682.4
kelch repeat and BTB (POZ) domain containing 4
chrX_+_47712614 0.22 ENSMUST00000114936.8
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr7_+_126446588 0.22 ENSMUST00000141805.8
ENSMUST00000064110.14
ENSMUST00000205938.2
ENSMUST00000152051.8
double C2, alpha
chr15_+_59186876 0.22 ENSMUST00000022977.14
ENSMUST00000100640.5
squalene epoxidase
chr17_+_35191661 0.22 ENSMUST00000007248.5
heat shock protein 1-like
chr2_+_164587948 0.22 ENSMUST00000109327.4
deoxynucleotidyltransferase, terminal, interacting protein 1
chr2_-_131001916 0.22 ENSMUST00000103188.10
ENSMUST00000133602.8
ENSMUST00000028800.12
RIKEN cDNA 1700037H04 gene
chr19_-_41884599 0.22 ENSMUST00000038677.5
ribosomal RNA processing 12 homolog
chr11_-_59730654 0.21 ENSMUST00000019517.10
COP9 signalosome subunit 3
chr16_-_91525655 0.21 ENSMUST00000117644.8
crystallin, zeta (quinone reductase)-like 1
chr6_-_83030759 0.21 ENSMUST00000134606.8
HtrA serine peptidase 2
chr5_+_138170259 0.21 ENSMUST00000019662.11
ENSMUST00000151318.8
adaptor-related protein complex AP-4, mu 1
chr2_+_125994050 0.21 ENSMUST00000170908.8
DTW domain containing 1
chr17_-_45903410 0.21 ENSMUST00000166119.8
solute carrier family 29 (nucleoside transporters), member 1
chr15_+_80832685 0.21 ENSMUST00000023043.10
ENSMUST00000164806.6
ENSMUST00000207170.2
ENSMUST00000168756.8
adenylosuccinate lyase
chr4_-_155753628 0.21 ENSMUST00000103176.10
mindbomb E3 ubiquitin protein ligase 2
chr14_-_56339915 0.20 ENSMUST00000015583.2
cathepsin G
chr13_-_100912308 0.20 ENSMUST00000075550.4
centromere protein H
chr8_-_84831391 0.20 ENSMUST00000041367.9
ENSMUST00000210279.2
DDB1 and CUL4 associated factor 15
chr14_-_86986541 0.20 ENSMUST00000226254.2
diaphanous related formin 3
chr10_+_39009951 0.20 ENSMUST00000019991.8
tubulin, epsilon 1
chr16_-_91525863 0.20 ENSMUST00000073466.13
crystallin, zeta (quinone reductase)-like 1
chr12_-_84455764 0.20 ENSMUST00000120942.8
ENSMUST00000110272.9
ectonucleoside triphosphate diphosphohydrolase 5
chr15_-_103123711 0.19 ENSMUST00000122182.2
ENSMUST00000108813.10
ENSMUST00000127191.2
chromobox 5
chr15_-_79025387 0.19 ENSMUST00000187550.7
ENSMUST00000188562.7
ENSMUST00000190509.7
ENSMUST00000190730.7
ENSMUST00000190959.7
ENSMUST00000169604.8
ENSMUST00000186053.7
RIKEN cDNA 1700088E04 gene
chr3_+_37366662 0.19 ENSMUST00000138710.3
ENSMUST00000057975.8
ENSMUST00000108121.4
predicted gene 43439
Bardet-Biedl syndrome 12 (human)
chr3_-_107992662 0.19 ENSMUST00000078912.7
adenosine monophosphate deaminase 2
chr14_-_55873026 0.19 ENSMUST00000125133.2
ENSMUST00000047131.16
importin 4
chr8_-_23295603 0.19 ENSMUST00000163739.3
ENSMUST00000210656.2
adaptor-related protein complex 3, mu 2 subunit
chr1_+_181952302 0.19 ENSMUST00000111018.2
ENSMUST00000027792.6
signal recognition particle 9
chr15_+_5173342 0.19 ENSMUST00000051186.9
ENSMUST00000228218.2
protein kinase, AMP-activated, alpha 1 catalytic subunit
chr7_+_16550198 0.19 ENSMUST00000108495.9
striatin, calmodulin binding protein 4
chr4_+_118478357 0.19 ENSMUST00000147373.2
EBNA1 binding protein 2
chr7_-_80550968 0.19 ENSMUST00000146402.2
ENSMUST00000026816.15
WD repeat domain 73
chr4_-_56802266 0.18 ENSMUST00000030140.3
elongator complex protein 1
chr5_-_138170644 0.18 ENSMUST00000000505.16
minichromosome maintenance complex component 7
chr5_+_21629932 0.18 ENSMUST00000056045.5
family with sequence similarity 185, member A
chr13_-_30170031 0.18 ENSMUST00000102948.11
E2F transcription factor 3
chr17_+_56611313 0.18 ENSMUST00000113035.8
ENSMUST00000113039.9
ENSMUST00000142387.2
ubiquitin-like, containing PHD and RING finger domains, 1
chr15_+_79113341 0.18 ENSMUST00000163571.8
protein interacting with C kinase 1
chr16_+_35861554 0.18 ENSMUST00000042203.10
WD repeat domain 5B
chr15_-_85918378 0.18 ENSMUST00000016172.10
cadherin, EGF LAG seven-pass G-type receptor 1
chr9_+_107926441 0.17 ENSMUST00000112295.9
GDP-mannose pyrophosphorylase B
chr9_+_63509925 0.17 ENSMUST00000041551.9
alpha- and gamma-adaptin binding protein
chr9_-_106563091 0.17 ENSMUST00000046735.11
testis expressed gene 264
chr11_+_22462088 0.17 ENSMUST00000059319.8
transmembrane protein 17
chr19_+_6111204 0.17 ENSMUST00000162726.5
zinc finger, HIT domain containing 2
chr3_+_105866685 0.17 ENSMUST00000010278.12
WD repeat domain 77
chr1_+_90531183 0.17 ENSMUST00000186750.2
COP9 signalosome subunit 8
chr8_+_85786684 0.17 ENSMUST00000095220.4
F-box and WD-40 domain protein 9
chr19_-_7218363 0.17 ENSMUST00000236769.2
N(alpha)-acetyltransferase 40, NatD catalytic subunit
chr11_+_3845221 0.17 ENSMUST00000109996.8
ENSMUST00000055931.5
dual specificity phosphatase 18
chr15_+_78312764 0.17 ENSMUST00000162517.8
ENSMUST00000166142.10
ENSMUST00000089414.11
potassium channel tetramerisation domain containing 17
chr2_-_35939377 0.17 ENSMUST00000070112.6
NADH:ubiquinone oxidoreductase subunit A8
chr17_-_56916771 0.17 ENSMUST00000052832.6
mitochondrial contact site and cristae organizing system subunit 13
chr4_-_154059495 0.17 ENSMUST00000030893.3
DNA fragmentation factor, beta subunit
chr17_+_79244553 0.16 ENSMUST00000024887.6
ENSMUST00000233068.2
ENSMUST00000233777.2
NADH:ubiquinone oxidoreductase complex assembly factor 7
chr17_-_34243608 0.16 ENSMUST00000025183.9
ring finger protein 1
chr7_-_79882313 0.16 ENSMUST00000206084.2
ENSMUST00000205996.2
ENSMUST00000071457.12
calcium and integrin binding 1 (calmyrin)
chr6_+_117883732 0.16 ENSMUST00000179224.8
ENSMUST00000035493.14
heterogeneous nuclear ribonucleoprotein F
chr11_+_87938128 0.16 ENSMUST00000139129.9
serine and arginine-rich splicing factor 1
chr16_-_93400691 0.16 ENSMUST00000023669.14
ENSMUST00000233931.2
ENSMUST00000154355.3
SET domain containing 4
chr10_-_68377672 0.16 ENSMUST00000020103.9
ciliary associated calcium binding coiled-coil 1
chr2_-_131016573 0.16 ENSMUST00000127987.2
sperm flagellar 1
chr18_-_24153805 0.16 ENSMUST00000066497.12
zinc finger protein 24
chr14_+_47605208 0.16 ENSMUST00000151405.9
lectin, galactose binding, soluble 3
chr11_+_109541747 0.16 ENSMUST00000049527.7
protein kinase, cAMP dependent regulatory, type I, alpha
chr10_-_62414236 0.16 ENSMUST00000065887.14
kinesin family binding protein
chr1_-_58735106 0.16 ENSMUST00000055313.14
ENSMUST00000188772.7
flagellum associated containing coiled-coil domains 1
chr16_-_4782031 0.16 ENSMUST00000023157.6
ENSMUST00000229765.2
ankyrin repeat and sterile alpha motif domain containing 3
chr1_-_75156993 0.16 ENSMUST00000027396.15
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr15_+_102240134 0.16 ENSMUST00000113682.9
ENSMUST00000001331.13
ENSMUST00000171244.2
melanocyte proliferating gene 1
chr11_-_74787877 0.16 ENSMUST00000057631.12
ENSMUST00000081799.6
small G protein signaling modulator 2
chr15_+_78312851 0.16 ENSMUST00000159771.8
potassium channel tetramerisation domain containing 17
chr15_+_25774070 0.16 ENSMUST00000125667.3
myosin X
chr1_+_135945798 0.16 ENSMUST00000117950.2
transmembrane protein 9
chr9_+_82711859 0.16 ENSMUST00000034783.6
interleukin-1 receptor-associated kinase 1 binding protein 1
chr7_-_133378468 0.16 ENSMUST00000033290.12
DEAH (Asp-Glu-Ala-His) box polypeptide 32
chr3_+_89970088 0.16 ENSMUST00000238911.2
ENSMUST00000029551.3
RIKEN cDNA 1700094D03 gene
chr11_-_101442663 0.16 ENSMUST00000017290.11
breast cancer 1, early onset
chr7_-_98790275 0.15 ENSMUST00000037968.10
UV radiation resistance associated gene
chr4_+_130001349 0.15 ENSMUST00000030563.6
penta-EF hand domain containing 1
chr5_-_129085558 0.15 ENSMUST00000100680.10
syntaxin 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Rfx3_Rfx1_Rfx4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.2 0.7 GO:1904569 regulation of selenocysteine incorporation(GO:1904569)
0.1 0.4 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.1 0.8 GO:0035026 leading edge cell differentiation(GO:0035026) cellular response to potassium ion starvation(GO:0051365)
0.1 0.5 GO:0038163 endomitotic cell cycle(GO:0007113) thrombopoietin-mediated signaling pathway(GO:0038163)
0.1 0.4 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.1 0.4 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.1 0.3 GO:0006713 glucocorticoid catabolic process(GO:0006713)
0.1 0.8 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.1 0.5 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.1 0.5 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 0.3 GO:0021508 floor plate formation(GO:0021508)
0.1 0.6 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.1 0.9 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.1 0.2 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.1 0.7 GO:1903753 negative regulation of p38MAPK cascade(GO:1903753)
0.1 0.3 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 0.2 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.1 0.3 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.1 0.2 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.1 0.4 GO:0010288 response to lead ion(GO:0010288)
0.1 0.3 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1 0.4 GO:0015862 uridine transport(GO:0015862)
0.1 0.2 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.1 0.2 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.1 0.2 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.1 0.2 GO:0018317 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1 0.3 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.1 0.2 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.1 0.2 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.1 0.4 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.0 0.5 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 1.1 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 0.3 GO:2001168 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.0 0.2 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.2 GO:0036451 cap mRNA methylation(GO:0036451)
0.0 0.2 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 0.2 GO:2000521 positive regulation of mononuclear cell migration(GO:0071677) negative regulation of immunological synapse formation(GO:2000521) regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001188) negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001189)
0.0 0.2 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.0 0.4 GO:2000580 regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.2 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.0 0.2 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.1 GO:0098501 polynucleotide dephosphorylation(GO:0098501)
0.0 0.2 GO:0045900 negative regulation of translational elongation(GO:0045900)
0.0 0.4 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.3 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.1 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.0 0.0 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.6 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.3 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.0 0.2 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.0 0.2 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.6 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.1 GO:2000845 positive regulation of testosterone secretion(GO:2000845)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.1 GO:0099542 diacylglycerol catabolic process(GO:0046340) trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542)
0.0 0.3 GO:0070944 neutrophil mediated killing of bacterium(GO:0070944)
0.0 0.1 GO:0014873 response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.0 0.2 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.1 GO:0006788 heme oxidation(GO:0006788)
0.0 0.1 GO:1901620 regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901620)
0.0 0.4 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.4 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.1 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0 0.8 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.0 0.0 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.4 GO:0071028 nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0 0.1 GO:2000331 positive regulation of Wnt protein secretion(GO:0061357) regulation of terminal button organization(GO:2000331)
0.0 0.0 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.2 GO:0015886 heme transport(GO:0015886)
0.0 0.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.0 0.2 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.1 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.0 0.5 GO:0007398 ectoderm development(GO:0007398)
0.0 0.2 GO:0070525 tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
0.0 0.4 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.2 GO:0036215 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.0 0.1 GO:0051661 maintenance of centrosome location(GO:0051661)
0.0 0.1 GO:0002248 connective tissue replacement involved in inflammatory response wound healing(GO:0002248)
0.0 0.1 GO:0071609 negative regulation of mitochondrial fusion(GO:0010637) negative regulation of defense response to virus by host(GO:0050689) chemokine (C-C motif) ligand 5 production(GO:0071609) regulation of chemokine (C-C motif) ligand 5 production(GO:0071649) positive regulation of macromitophagy(GO:1901526) regulation of mitophagy in response to mitochondrial depolarization(GO:1904923) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.0 0.4 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.2 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.1 GO:1904736 negative regulation of electron carrier activity(GO:1904733) regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:1904735) negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:1904736)
0.0 0.2 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.2 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.1 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.2 GO:0032261 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.0 0.2 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.0 0.0 GO:0031662 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662)
0.0 0.1 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.2 GO:0071494 cellular response to UV-C(GO:0071494)
0.0 0.1 GO:0042723 thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.0 0.1 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.0 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.3 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 0.4 GO:0042026 protein refolding(GO:0042026)
0.0 0.0 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.1 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.1 GO:0039019 pronephric nephron development(GO:0039019)
0.0 0.0 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342)
0.0 0.1 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.0 0.1 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.8 GO:1901998 toxin transport(GO:1901998)
0.0 0.0 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.8 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.1 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.1 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.2 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.6 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.0 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822)
0.0 0.5 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.5 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.4 GO:0006458 'de novo' protein folding(GO:0006458)
0.0 0.1 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.0 GO:0009826 unidimensional cell growth(GO:0009826)
0.0 0.0 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.0 0.1 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.0 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.0 0.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.0 GO:0090345 nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210) cellular organohalogen metabolic process(GO:0090345) cellular organofluorine metabolic process(GO:0090346)
0.0 0.2 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.2 GO:0010216 maintenance of DNA methylation(GO:0010216) regulation of methylation-dependent chromatin silencing(GO:0090308)
0.0 0.1 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.0 0.2 GO:0051382 kinetochore assembly(GO:0051382)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0035976 AP1 complex(GO:0035976)
0.2 0.6 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 0.3 GO:0098842 postsynaptic early endosome(GO:0098842)
0.1 1.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.2 GO:1990769 proximal neuron projection(GO:1990769)
0.1 0.4 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.1 0.4 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.1 0.6 GO:0005787 signal peptidase complex(GO:0005787)
0.1 0.9 GO:0036038 MKS complex(GO:0036038)
0.1 0.2 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.1 0.4 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 1.5 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.6 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.2 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.4 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.7 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.3 GO:0033503 HULC complex(GO:0033503)
0.0 0.6 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.9 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.2 GO:0034709 methylosome(GO:0034709)
0.0 0.2 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.7 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.2 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.2 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.3 GO:0061700 GATOR2 complex(GO:0061700)
0.0 1.0 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.1 GO:0031523 Myb complex(GO:0031523)
0.0 0.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.1 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 0.6 GO:0032433 filopodium tip(GO:0032433)
0.0 0.1 GO:0034456 CURI complex(GO:0032545) UTP-C complex(GO:0034456)
0.0 0.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.2 GO:0097542 ciliary tip(GO:0097542)
0.0 0.1 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.1 GO:1990630 IRE1-RACK1-PP2A complex(GO:1990630)
0.0 0.2 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.1 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.1 GO:1990423 RZZ complex(GO:1990423)
0.0 0.2 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.0 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0 0.4 GO:0010369 chromocenter(GO:0010369)
0.0 1.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.2 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.1 GO:0070449 elongin complex(GO:0070449)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.2 GO:0042555 MCM complex(GO:0042555)
0.0 0.2 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.1 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.6 GO:0005788 endoplasmic reticulum lumen(GO:0005788)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.2 0.9 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.2 1.5 GO:1901612 cardiolipin binding(GO:1901612)
0.1 0.7 GO:0070568 guanylyltransferase activity(GO:0070568)
0.1 0.3 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 0.5 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.1 0.9 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.2 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.1 0.3 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 0.7 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.3 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.1 0.7 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.1 0.2 GO:0050785 advanced glycation end-product receptor activity(GO:0050785)
0.1 0.2 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.2 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.0 0.1 GO:0052692 raffinose alpha-galactosidase activity(GO:0052692)
0.0 0.1 GO:0015152 glucose-6-phosphate transmembrane transporter activity(GO:0015152)
0.0 0.8 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.6 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.2 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.0 0.2 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.0 0.1 GO:0001729 ceramide kinase activity(GO:0001729)
0.0 0.1 GO:0016034 maleylacetoacetate isomerase activity(GO:0016034)
0.0 0.2 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.3 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.4 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.3 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.2 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.2 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 1.4 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.1 GO:0046403 polynucleotide 3'-phosphatase activity(GO:0046403)
0.0 0.2 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.1 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 1.3 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.2 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.1 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.0 0.3 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.0 0.1 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.3 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.2 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.0 0.4 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 0.1 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.0 0.2 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.4 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 0.1 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.0 0.3 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.1 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 0.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.2 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.7 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.1 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 1.1 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.1 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0 0.3 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.1 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.0 0.1 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.0 0.6 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.2 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.1 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.1 GO:0034452 dynactin binding(GO:0034452)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.0 GO:0036004 GAF domain binding(GO:0036004)
0.0 0.4 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.3 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.2 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.1 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.0 0.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.2 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.2 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0 0.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.1 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 0.0 GO:0047726 nitric oxide dioxygenase activity(GO:0008941) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor(GO:0016708) iron-cytochrome-c reductase activity(GO:0047726)
0.0 0.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.1 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.1 GO:0015215 nucleotide transmembrane transporter activity(GO:0015215)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.0 GO:0033883 pyridoxal phosphatase activity(GO:0033883)
0.0 1.1 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.3 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.6 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 1.2 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.5 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.6 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.6 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.8 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.6 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 1.1 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.0 0.4 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.6 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.4 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.3 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.1 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.7 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.6 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.3 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.8 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.8 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.1 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 0.2 REACTOME ASSEMBLY OF THE PRE REPLICATIVE COMPLEX Genes involved in Assembly of the pre-replicative complex
0.0 0.6 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.4 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.8 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.4 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha