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avrg: GFI1 WT vs 36n/n vs KD

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Results for Scrt2

Z-value: 0.86

Motif logo

Transcription factors associated with Scrt2

Gene Symbol Gene ID Gene Info
ENSMUSG00000060257.3 scratch family zinc finger 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Scrt2mm39_v1_chr2_+_151923449_1519235440.847.3e-02Click!

Activity profile of Scrt2 motif

Sorted Z-values of Scrt2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chrX_-_71318353 1.47 ENSMUST00000064780.4
gamma-aminobutyric acid (GABA) A receptor, subunit epsilon
chr13_+_23940964 1.14 ENSMUST00000102965.4
H4 clustered histone 2
chr3_-_122778052 0.64 ENSMUST00000199401.2
ENSMUST00000197314.5
ENSMUST00000197934.5
ENSMUST00000090379.7
ubiquitin specific peptidase 53
chr1_-_156767123 0.63 ENSMUST00000189316.7
ENSMUST00000190648.7
ENSMUST00000172057.8
ENSMUST00000191605.7
Ral GEF with PH domain and SH3 binding motif 2
chr8_+_91635192 0.58 ENSMUST00000211403.2
chromodomain helicase DNA binding protein 9
chr13_+_109397184 0.50 ENSMUST00000153234.8
phosphodiesterase 4D, cAMP specific
chr1_+_182236728 0.47 ENSMUST00000117245.2
transformation related protein 53 binding protein 2
chrX_-_132882514 0.47 ENSMUST00000113297.9
ENSMUST00000174542.2
ENSMUST00000033608.15
ENSMUST00000113294.8
synaptotagmin-like 4
chr4_-_155947819 0.45 ENSMUST00000030949.4
taste receptor, type 1, member 3
chr2_-_60711706 0.45 ENSMUST00000164147.8
ENSMUST00000112509.2
RNA binding motif, single stranded interacting protein 1
chr16_+_16888145 0.43 ENSMUST00000232574.2
yippee like 1
chr2_-_168432111 0.42 ENSMUST00000029057.13
ENSMUST00000074618.10
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2
chr4_-_135221810 0.35 ENSMUST00000105856.9
NIPA-like domain containing 3
chr16_+_3702493 0.34 ENSMUST00000176233.2
predicted gene 20695
chr16_+_16887991 0.34 ENSMUST00000232258.2
yippee like 1
chr2_-_168432235 0.33 ENSMUST00000109184.8
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2
chr10_+_56253418 0.32 ENSMUST00000068581.9
ENSMUST00000217789.2
gap junction protein, alpha 1
chr18_+_36693024 0.32 ENSMUST00000134146.8
ankyrin repeat and KH domain containing 1
chr2_-_148574353 0.31 ENSMUST00000028926.13
N-ethylmaleimide sensitive fusion protein attachment protein beta
chrX_+_149330371 0.31 ENSMUST00000066337.13
ENSMUST00000112715.2
aminolevulinic acid synthase 2, erythroid
chr7_+_24990596 0.30 ENSMUST00000164820.2
capicua transcriptional repressor
chr17_-_56019571 0.29 ENSMUST00000086876.7
ENSMUST00000233557.2
ENSMUST00000233972.2
protection of telomeres 1B
chr17_+_44499451 0.29 ENSMUST00000024755.7
chloride intracellular channel 5
chr5_-_137609691 0.28 ENSMUST00000031731.14
procollagen C-endopeptidase enhancer protein
chr7_-_30672824 0.27 ENSMUST00000147431.2
ENSMUST00000098553.11
ENSMUST00000108116.10
lipolysis stimulated lipoprotein receptor
chr3_+_37402795 0.27 ENSMUST00000200585.5
ENSMUST00000038885.10
fibroblast growth factor 2
chr8_-_103512274 0.26 ENSMUST00000075190.5
cadherin 11
chr11_-_106504196 0.26 ENSMUST00000128933.2
testis expressed gene 2
chr3_-_67282496 0.25 ENSMUST00000166353.2
predicted gene, 17402
chr1_-_156767196 0.25 ENSMUST00000185198.7
Ral GEF with PH domain and SH3 binding motif 2
chr19_-_61216834 0.23 ENSMUST00000076046.7
colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
chr3_-_108747792 0.23 ENSMUST00000106596.4
ENSMUST00000102621.11
ENSMUST00000138552.6
syntaxin binding protein 3
chr17_-_24752683 0.23 ENSMUST00000061764.14
RAB26, member RAS oncogene family
chr9_-_50650663 0.22 ENSMUST00000117093.2
ENSMUST00000121634.8
DIX domain containing 1
chr18_-_46444941 0.22 ENSMUST00000072835.7
coiled-coil domain containing 112
chr1_-_24139263 0.21 ENSMUST00000187369.7
ENSMUST00000187752.7
ENSMUST00000186999.7
family with sequence similarity 135, member A
chr12_+_4642987 0.21 ENSMUST00000062580.8
ENSMUST00000220311.2
intersectin 2
chr5_-_137609634 0.21 ENSMUST00000054564.13
procollagen C-endopeptidase enhancer protein
chr1_-_24139387 0.21 ENSMUST00000027337.15
family with sequence similarity 135, member A
chr8_-_84874468 0.20 ENSMUST00000117424.9
ENSMUST00000040383.9
coiled-coil and C2 domain containing 1A
chr2_+_112096154 0.20 ENSMUST00000110991.9
solute carrier family 12, member 6
chr6_-_90693471 0.20 ENSMUST00000101153.10
IQ motif and Sec7 domain 1
chr16_+_3702523 0.20 ENSMUST00000176625.8
ENSMUST00000186375.8
N(alpha)-acetyltransferase 60, NatF catalytic subunit
chr1_-_5987617 0.19 ENSMUST00000044180.5
neuropeptides B/W receptor 1
chr12_+_105302853 0.19 ENSMUST00000180458.9
Tcl1 upstream neural differentiation associated RNA
chr1_-_192880260 0.18 ENSMUST00000161367.2
TRAF3 interacting protein 3
chr19_+_24976864 0.17 ENSMUST00000025831.8
dedicator of cytokinesis 8
chr15_-_77331660 0.17 ENSMUST00000089469.7
apolipoprotein L 7b
chr5_-_137145030 0.16 ENSMUST00000054384.6
ENSMUST00000152207.2
tripartite motif-containing 56
chr17_-_26063488 0.16 ENSMUST00000176709.2
ras homolog family member T2
chr15_+_77583104 0.15 ENSMUST00000096358.6
apolipoprotein L 7e
chrX_+_84091915 0.15 ENSMUST00000239019.2
ENSMUST00000113992.3
ENSMUST00000113991.8
dystrophin, muscular dystrophy
chr7_-_65020655 0.15 ENSMUST00000032729.8
tight junction protein 1
chr1_-_156766957 0.14 ENSMUST00000171292.8
ENSMUST00000063199.13
ENSMUST00000027886.14
Ral GEF with PH domain and SH3 binding motif 2
chr2_+_112097087 0.14 ENSMUST00000110987.9
ENSMUST00000028549.14
solute carrier family 12, member 6
chr6_-_53797748 0.14 ENSMUST00000127748.5
TLR4 interactor with leucine-rich repeats
chr15_+_102898966 0.13 ENSMUST00000001703.8
homeobox C8
chr15_-_71599664 0.13 ENSMUST00000022953.10
family with sequence similarity 135, member B
chr7_-_30672889 0.13 ENSMUST00000001279.15
lipolysis stimulated lipoprotein receptor
chr9_-_21763898 0.13 ENSMUST00000217336.2
ENSMUST00000034728.9
dedicator of cytokinesis 6
chr13_-_81781238 0.12 ENSMUST00000126444.8
ENSMUST00000128585.9
ENSMUST00000146749.2
ENSMUST00000095585.11
adhesion G protein-coupled receptor V1
chr7_+_44465353 0.12 ENSMUST00000208626.2
ENSMUST00000057195.17
nucleoporin 62
chr10_-_79449826 0.11 ENSMUST00000059699.9
ENSMUST00000178228.3
C2 calcium-dependent domain containing 4C
chr16_+_42727926 0.11 ENSMUST00000151244.8
ENSMUST00000114694.9
zinc finger and BTB domain containing 20
chr1_-_156766381 0.11 ENSMUST00000188656.7
Ral GEF with PH domain and SH3 binding motif 2
chr1_+_64729950 0.11 ENSMUST00000187170.7
cyclin Y-like 1
chr8_-_85663976 0.11 ENSMUST00000109741.9
ENSMUST00000119820.2
microtubule associated serine/threonine kinase 1
chr7_-_30672747 0.10 ENSMUST00000205961.2
lipolysis stimulated lipoprotein receptor
chr7_+_100742070 0.10 ENSMUST00000208439.2
FCH and double SH3 domains 2
chr11_+_77384234 0.10 ENSMUST00000037285.10
ENSMUST00000100812.4
GIT ArfGAP 1
chr7_+_89779421 0.09 ENSMUST00000207225.2
ENSMUST00000207484.2
ENSMUST00000209068.2
phosphatidylinositol binding clathrin assembly protein
chr15_+_44320918 0.09 ENSMUST00000038336.12
ENSMUST00000166957.2
ENSMUST00000209244.2
polycystic kidney and hepatic disease 1-like 1
chr12_+_113061819 0.09 ENSMUST00000109727.9
ENSMUST00000009099.13
ENSMUST00000109723.8
ENSMUST00000109726.8
ENSMUST00000069690.5
metastasis associated 1
chr11_-_76514334 0.09 ENSMUST00000238684.2
active BCR-related gene
chr2_+_121188195 0.08 ENSMUST00000125812.8
ENSMUST00000078222.9
ENSMUST00000125221.3
ENSMUST00000150271.8
creatine kinase, mitochondrial 1, ubiquitous
chr11_-_55310724 0.08 ENSMUST00000108858.8
ENSMUST00000141530.2
secreted acidic cysteine rich glycoprotein
chr7_-_100504610 0.08 ENSMUST00000156855.8
RELT tumor necrosis factor receptor
chr4_+_40269563 0.08 ENSMUST00000129758.3
small integral membrane protein 27
chr7_-_24950145 0.08 ENSMUST00000116343.3
ENSMUST00000045847.15
Ets2 repressor factor
chr2_-_164285097 0.08 ENSMUST00000017153.4
syndecan 4
chr10_+_116137277 0.07 ENSMUST00000092167.7
protein tyrosine phosphatase, receptor type, B
chr3_-_108747767 0.07 ENSMUST00000196679.5
syntaxin binding protein 3
chr6_-_23839136 0.07 ENSMUST00000166458.9
ENSMUST00000142913.9
ENSMUST00000069074.14
ENSMUST00000115361.9
ENSMUST00000018122.14
ENSMUST00000115356.3
Ca2+-dependent activator protein for secretion 2
chr7_+_89779493 0.07 ENSMUST00000208730.2
phosphatidylinositol binding clathrin assembly protein
chr14_+_31750946 0.07 ENSMUST00000022460.11
polypeptide N-acetylgalactosaminyltransferase 15
chr2_-_30014466 0.07 ENSMUST00000044751.14
zyg-11 related, cell cycle regulator
chr1_+_183078851 0.07 ENSMUST00000193625.2
axin interactor, dorsalization associated
chr16_+_16888084 0.07 ENSMUST00000231514.2
yippee like 1
chr7_+_104335708 0.06 ENSMUST00000214876.2
olfactory receptor 661
chr12_+_4642629 0.06 ENSMUST00000218402.2
intersectin 2
chr4_-_129083439 0.06 ENSMUST00000106059.8
S100P binding protein
chr15_+_34306812 0.06 ENSMUST00000226766.2
ENSMUST00000163455.9
ENSMUST00000022947.7
ENSMUST00000228570.2
ENSMUST00000227759.2
matrilin 2
chr1_-_183150867 0.05 ENSMUST00000194543.4
melanoma inhibitory activity 3
chrX_+_151922936 0.05 ENSMUST00000039720.11
ENSMUST00000144175.3
Ras-related GTP binding B
chr12_+_65083093 0.05 ENSMUST00000120580.8
pre-mRNA processing factor 39
chr5_+_118307754 0.05 ENSMUST00000054836.7
harakiri, BCL2 interacting protein (contains only BH3 domain)
chr1_-_155912216 0.05 ENSMUST00000027738.14
torsin A interacting protein 1
chr19_-_56996617 0.05 ENSMUST00000118800.8
ENSMUST00000111584.9
ENSMUST00000122359.8
ENSMUST00000148049.8
actin filament associated protein 1-like 2
chr14_-_61495934 0.05 ENSMUST00000077954.13
sarcoglycan, gamma (dystrophin-associated glycoprotein)
chr5_-_100521343 0.05 ENSMUST00000182433.8
Sec31 homolog A (S. cerevisiae)
chr7_+_89779564 0.05 ENSMUST00000208742.2
ENSMUST00000049537.9
phosphatidylinositol binding clathrin assembly protein
chr6_-_86646118 0.05 ENSMUST00000001184.10
MAX dimerization protein 1
chr7_+_30673212 0.04 ENSMUST00000129773.2
family with sequence similarity 187, member B
chr4_-_106474429 0.04 ENSMUST00000189032.7
ENSMUST00000106788.2
lymphocyte expansion molecule
chr16_+_3702604 0.04 ENSMUST00000115860.8
N(alpha)-acetyltransferase 60, NatF catalytic subunit
chr9_-_27066685 0.03 ENSMUST00000034472.16
junction adhesion molecule 3
chr7_-_134539993 0.03 ENSMUST00000171394.3
inhibitory synaptic factor 2A
chr3_-_57209357 0.03 ENSMUST00000196979.5
ENSMUST00000029376.13
transmembrane 4 superfamily member 1
chrX_+_5959507 0.03 ENSMUST00000103007.4
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr2_-_169973076 0.03 ENSMUST00000063710.13
zinc finger protein 217
chr17_+_34573760 0.02 ENSMUST00000178562.2
ENSMUST00000025198.15
butyrophilin-like 2
chr10_-_79973210 0.02 ENSMUST00000170219.9
ENSMUST00000169546.9
calcium channel, voltage-dependent, beta subunit associated regulatory protein
chr13_-_53135064 0.02 ENSMUST00000071065.8
nuclear factor, interleukin 3, regulated
chr12_-_11200306 0.02 ENSMUST00000055673.2
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3
chr6_-_85742726 0.01 ENSMUST00000050780.8
N-acetyltransferase 8 (GCN5-related) family member 3
chr1_-_156766351 0.01 ENSMUST00000189648.2
Ral GEF with PH domain and SH3 binding motif 2
chr1_+_120530134 0.01 ENSMUST00000079721.9
engrailed 1
chr11_+_103540391 0.01 ENSMUST00000057870.4
reprimo-like
chr19_+_4889394 0.01 ENSMUST00000088653.3
coiled-coil domain containing 87
chr2_-_126625343 0.01 ENSMUST00000028842.9
ENSMUST00000130356.3
ubiquitin specific peptidase 50
chr11_-_107805830 0.01 ENSMUST00000039071.3
calcium channel, voltage-dependent, gamma subunit 5
chr10_-_19727165 0.01 ENSMUST00000059805.6
solute carrier family 35, member D3
chr10_+_116013256 0.00 ENSMUST00000155606.8
ENSMUST00000128399.2
protein tyrosine phosphatase, receptor type, R
chr10_-_109669053 0.00 ENSMUST00000238286.2
neuron navigator 3
chr2_+_153334710 0.00 ENSMUST00000109783.2
RIKEN cDNA 4930404H24 gene
chr2_+_152753231 0.00 ENSMUST00000028970.8
myosin, light polypeptide kinase 2, skeletal muscle
chr18_-_82424902 0.00 ENSMUST00000065224.8
galanin receptor 1
chr7_-_118047394 0.00 ENSMUST00000203796.4
ENSMUST00000203485.3
synaptotagmin XVII
chrX_-_78560891 0.00 ENSMUST00000197180.6
ENSMUST00000101410.3
cilia and flagella associated protein 47
chr16_+_20514925 0.00 ENSMUST00000128273.2
family with sequence similarity 131, member A
chr7_+_106969919 0.00 ENSMUST00000137663.2
synaptotagmin IX
chrX_-_151552457 0.00 ENSMUST00000101141.9
ENSMUST00000062317.5
shroom family member 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Scrt2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.1 1.1 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.1 0.3 GO:0003294 atrial ventricular junction remodeling(GO:0003294) regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.1 0.3 GO:0072695 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.1 0.3 GO:0021762 substantia nigra development(GO:0021762)
0.1 0.3 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 0.5 GO:0050916 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.1 0.4 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.1 0.2 GO:0021629 olfactory nerve morphogenesis(GO:0021627) olfactory nerve structural organization(GO:0021629)
0.0 0.5 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.2 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 1.5 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.8 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.3 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.0 0.5 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.1 GO:1903438 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.0 0.3 GO:0022615 protein to membrane docking(GO:0022615)
0.0 0.1 GO:0031104 dendrite regeneration(GO:0031104)
0.0 0.3 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.1 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.1 GO:2000016 negative regulation of determination of dorsal identity(GO:2000016)
0.0 0.3 GO:0002024 diet induced thermogenesis(GO:0002024)
0.0 0.2 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.3 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.0 GO:1990504 dense core granule exocytosis(GO:1990504)
0.0 0.3 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.0 0.6 GO:0010996 response to auditory stimulus(GO:0010996)
0.0 0.1 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.0 0.3 GO:0001771 immunological synapse formation(GO:0001771)
0.0 0.2 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011)
0.0 0.1 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0061689 tricellular tight junction(GO:0061689)
0.1 0.3 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.3 GO:0070820 tertiary granule(GO:0070820)
0.0 0.2 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.1 GO:1990696 stereocilia ankle link complex(GO:0002142) USH2 complex(GO:1990696)
0.0 0.3 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 0.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.3 GO:0005922 fascia adherens(GO:0005916) connexon complex(GO:0005922)
0.0 0.1 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.1 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.1 0.3 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
0.1 0.2 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.1 0.2 GO:0019002 GMP binding(GO:0019002)
0.1 0.3 GO:1903763 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075) gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.1 0.3 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 1.5 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.3 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.5 GO:0008527 taste receptor activity(GO:0008527)
0.0 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.5 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.1 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.1 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.1 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.3 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events