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avrg: GFI1 WT vs 36n/n vs KD

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Results for Spdef

Z-value: 2.24

Motif logo

Transcription factors associated with Spdef

Gene Symbol Gene ID Gene Info
ENSMUSG00000024215.15 SAM pointed domain containing ets transcription factor

Activity profile of Spdef motif

Sorted Z-values of Spdef motif

Promoter Log-likelihood Transcript Gene Gene Info
chr13_+_22017906 2.09 ENSMUST00000180288.2
H2B clustered histone 24
chr13_-_21900313 2.06 ENSMUST00000091756.2
H2B clustered histone 13
chr13_+_21906214 1.86 ENSMUST00000224651.2
H2B clustered histone 14
chr13_+_22227359 1.85 ENSMUST00000110452.2
H2B clustered histone 11
chr2_+_129854256 1.75 ENSMUST00000110299.3
transglutaminase 3, E polypeptide
chr19_+_8975249 1.72 ENSMUST00000236390.2
AHNAK nucleoprotein (desmoyokin)
chr9_+_57818243 1.58 ENSMUST00000216925.2
ENSMUST00000163329.2
ENSMUST00000213654.2
ENSMUST00000217132.2
ENSMUST00000216841.2
ENSMUST00000214086.2
ubiquitin-like 7 (bone marrow stromal cell-derived)
chr11_+_70538083 1.40 ENSMUST00000037534.8
ring finger protein 167
chr14_-_55909314 1.37 ENSMUST00000163750.8
neural precursor cell expressed, developmentally down-regulated gene 8
chr10_+_17598961 1.34 ENSMUST00000038107.9
ENSMUST00000219558.2
ENSMUST00000218370.2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr17_+_34808772 1.28 ENSMUST00000038244.15
G-protein signalling modulator 3 (AGS3-like, C. elegans)
chr6_-_97408367 1.17 ENSMUST00000124050.3
FERM domain containing 4B
chr14_-_55909527 1.16 ENSMUST00000010520.10
neural precursor cell expressed, developmentally down-regulated gene 8
chr9_+_20555629 1.12 ENSMUST00000161887.8
ubiquitin-like 5
chr16_-_4698148 1.05 ENSMUST00000037843.7
UBA-like domain containing 1
chr12_-_31549538 0.97 ENSMUST00000064240.14
ENSMUST00000185739.8
ENSMUST00000188326.3
ENSMUST00000101499.10
ENSMUST00000085487.12
Casitas B-lineage lymphoma-like 1
chr9_-_43027809 0.93 ENSMUST00000216126.2
ENSMUST00000213544.2
ENSMUST00000061833.6
TLC domain containing 5
chr13_-_22227114 0.91 ENSMUST00000091741.6
H2A clustered histone 11
chr6_+_35229589 0.90 ENSMUST00000152147.8
RIKEN cDNA 1810058I24 gene
chr8_-_123768984 0.88 ENSMUST00000212937.2
ankyrin repeat domain 11
chr9_-_41068771 0.85 ENSMUST00000136530.8
ubiquitin associated and SH3 domain containing, B
chr3_-_122778052 0.83 ENSMUST00000199401.2
ENSMUST00000197314.5
ENSMUST00000197934.5
ENSMUST00000090379.7
ubiquitin specific peptidase 53
chr2_-_168432111 0.82 ENSMUST00000029057.13
ENSMUST00000074618.10
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2
chr8_-_70963202 0.81 ENSMUST00000125184.8
ubiquitin A-52 residue ribosomal protein fusion product 1
chr11_-_119246310 0.80 ENSMUST00000100172.3
ENSMUST00000005173.11
N-sulfoglucosamine sulfohydrolase (sulfamidase)
chr2_-_127050161 0.80 ENSMUST00000056146.2
RIKEN cDNA 1810024B03 gene
chr14_-_54491365 0.75 ENSMUST00000128231.2
defender against cell death 1
chr8_+_114362181 0.75 ENSMUST00000179926.9
MON1 homolog B, secretory traffciking associated
chr7_+_19699291 0.74 ENSMUST00000094753.6
carcinoembryonic antigen-related cell adhesion molecule 20
chr8_+_114362419 0.73 ENSMUST00000035777.10
MON1 homolog B, secretory traffciking associated
chr7_-_46569617 0.72 ENSMUST00000210664.2
ENSMUST00000156335.9
tumor susceptibility gene 101
chr16_-_92622972 0.70 ENSMUST00000023673.14
runt related transcription factor 1
chr7_+_127078371 0.70 ENSMUST00000205432.3
fibrosin
chr5_-_31065036 0.70 ENSMUST00000132034.5
ENSMUST00000132253.5
oligosaccharyltransferase complex subunit 4 (non-catalytic)
chr11_-_86574586 0.70 ENSMUST00000018315.10
vacuole membrane protein 1
chr7_+_27878894 0.69 ENSMUST00000085901.13
ENSMUST00000172761.8
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr10_-_95159933 0.68 ENSMUST00000053594.7
CASP2 and RIPK1 domain containing adaptor with death domain
chr7_-_46569662 0.67 ENSMUST00000143413.3
ENSMUST00000014546.15
tumor susceptibility gene 101
chr1_+_138891155 0.66 ENSMUST00000200533.5
DENN/MADD domain containing 1B
chr6_-_99073156 0.66 ENSMUST00000175886.8
forkhead box P1
chr12_+_102249294 0.65 ENSMUST00000056950.14
Ras and Rab interactor 3
chr9_-_110305705 0.65 ENSMUST00000198164.5
ENSMUST00000068025.13
kelch-like 18
chr9_+_102503476 0.65 ENSMUST00000190279.7
ENSMUST00000188398.7
anaphase promoting complex subunit 13
chr15_+_35371300 0.65 ENSMUST00000048646.9
vacuolar protein sorting 13B
chr13_-_74956924 0.63 ENSMUST00000223206.2
calpastatin
chr9_+_110306052 0.63 ENSMUST00000197248.5
ENSMUST00000061155.12
ENSMUST00000198043.5
ENSMUST00000084952.8
kinesin family member 9
chr2_-_168432235 0.62 ENSMUST00000109184.8
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2
chr12_+_76593799 0.61 ENSMUST00000218380.2
ENSMUST00000219751.2
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr3_+_137573436 0.59 ENSMUST00000090178.10
DnaJ heat shock protein family (Hsp40) member B14
chr2_+_71884943 0.57 ENSMUST00000028525.6
Rap guanine nucleotide exchange factor (GEF) 4
chrX_-_12628309 0.56 ENSMUST00000096495.11
ENSMUST00000076016.6
mediator complex subunit 14
chr7_+_130375799 0.56 ENSMUST00000048453.7
ENSMUST00000208593.2
BTB (POZ) domain containing 16
chr5_+_124577952 0.56 ENSMUST00000059580.11
lysine methyltransferase 5A
chr9_+_117869642 0.55 ENSMUST00000134433.8
5-azacytidine induced gene 2
chr19_+_6413703 0.55 ENSMUST00000131252.8
ENSMUST00000113489.8
splicing factor 1
chr7_+_127475968 0.55 ENSMUST00000131000.2
zinc finger protein 646
chr8_-_70448872 0.54 ENSMUST00000177851.9
GATA zinc finger domain containing 2A
chr13_+_41040657 0.54 ENSMUST00000069958.15
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr8_-_123768759 0.53 ENSMUST00000098334.13
ankyrin repeat domain 11
chr16_-_17540805 0.52 ENSMUST00000012259.9
ENSMUST00000232236.2
mediator complex subunit 15
chr13_-_59970383 0.52 ENSMUST00000225987.2
terminal uridylyl transferase 7
chr15_-_36609812 0.52 ENSMUST00000226496.2
poly(A) binding protein, cytoplasmic 1
chr16_-_17540685 0.52 ENSMUST00000232163.2
ENSMUST00000232202.2
ENSMUST00000080936.14
ENSMUST00000232645.2
ENSMUST00000232431.2
mediator complex subunit 15
chr4_-_156312961 0.52 ENSMUST00000217885.2
pleckstrin homology domain containing, family N member 1
chr15_+_78912642 0.51 ENSMUST00000180086.3
H1.0 linker histone
chr5_-_100563974 0.51 ENSMUST00000182886.8
ENSMUST00000094578.11
Sec31 homolog A (S. cerevisiae)
chr9_+_57818384 0.51 ENSMUST00000217129.2
ubiquitin-like 7 (bone marrow stromal cell-derived)
chrX_+_109857866 0.50 ENSMUST00000078229.5
POU domain, class 3, transcription factor 4
chr14_-_32907446 0.50 ENSMUST00000159606.2
WD repeat and FYVE domain containing 4
chr7_+_27879650 0.50 ENSMUST00000172467.8
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr12_+_102249375 0.50 ENSMUST00000101114.11
ENSMUST00000150795.8
Ras and Rab interactor 3
chr13_+_41013230 0.49 ENSMUST00000110191.10
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr2_-_34262012 0.49 ENSMUST00000113132.9
ENSMUST00000040638.15
pre B cell leukemia homeobox 3
chr4_-_156312996 0.49 ENSMUST00000105571.4
pleckstrin homology domain containing, family N member 1
chr9_-_57743989 0.49 ENSMUST00000164010.8
ENSMUST00000171444.8
ENSMUST00000098686.4
AT rich interactive domain 3B (BRIGHT-like)
chr19_+_6097111 0.48 ENSMUST00000025723.9
synovial apoptosis inhibitor 1, synoviolin
chr4_-_122779837 0.48 ENSMUST00000106255.8
ENSMUST00000106257.10
CAP, adenylate cyclase-associated protein 1 (yeast)
chr19_+_6096606 0.48 ENSMUST00000138532.8
ENSMUST00000129081.8
ENSMUST00000156550.8
synovial apoptosis inhibitor 1, synoviolin
chr4_-_63321591 0.48 ENSMUST00000035724.5
AT-hook transcription factor
chr8_-_70449018 0.48 ENSMUST00000065169.12
ENSMUST00000212478.2
GATA zinc finger domain containing 2A
chr13_-_59970885 0.47 ENSMUST00000225179.2
ENSMUST00000225576.2
ENSMUST00000071703.6
terminal uridylyl transferase 7
chr9_+_20556088 0.46 ENSMUST00000162303.8
ENSMUST00000161486.8
ubiquitin-like 5
chr3_-_84489923 0.46 ENSMUST00000143514.3
ADP-ribosylation factor interacting protein 1
chr11_-_73742280 0.46 ENSMUST00000213365.2
olfactory receptor 393
chr7_+_101619897 0.45 ENSMUST00000211272.2
nuclear mitotic apparatus protein 1
chr5_+_117271632 0.44 ENSMUST00000179276.8
ENSMUST00000092889.12
ENSMUST00000145640.8
TAO kinase 3
chr9_+_20556147 0.44 ENSMUST00000161882.8
ubiquitin-like 5
chr17_+_34159633 0.44 ENSMUST00000025170.11
WD repeat domain 46
chr4_+_44756608 0.43 ENSMUST00000143385.2
zinc finger, CCHC domain containing 7
chr9_+_117869543 0.43 ENSMUST00000044454.12
5-azacytidine induced gene 2
chr13_-_104057016 0.43 ENSMUST00000022222.12
Erbb2 interacting protein
chr1_+_39407183 0.43 ENSMUST00000195123.6
ribosomal protein L31
chr14_-_98406977 0.42 ENSMUST00000071533.13
ENSMUST00000069334.8
dachshund family transcription factor 1
chr8_-_64659004 0.42 ENSMUST00000066166.6
tolloid-like
chr17_-_51486196 0.42 ENSMUST00000024717.10
ENSMUST00000224528.2
TBC1 domain family, member 5
chr1_-_23961379 0.41 ENSMUST00000027339.14
small ArfGAP 1
chr11_-_98329782 0.41 ENSMUST00000002655.8
migration and invasion enhancer 1
chr17_+_29487762 0.41 ENSMUST00000064709.13
ENSMUST00000234711.2
cDNA sequence BC004004
chr11_-_70545450 0.40 ENSMUST00000018437.3
profilin 1
chr8_+_72973560 0.40 ENSMUST00000003123.10
family with sequence similarity 32, member A
chr11_+_69214789 0.40 ENSMUST00000102602.8
trafficking protein particle complex 1
chr9_+_117869577 0.40 ENSMUST00000133580.8
5-azacytidine induced gene 2
chr1_-_171910324 0.39 ENSMUST00000003550.11
nicastrin
chr2_+_145627900 0.39 ENSMUST00000110005.8
ENSMUST00000094480.11
Ras and Rab interactor 2
chr11_-_103254257 0.39 ENSMUST00000092557.6
Rho GTPase activating protein 27
chr15_-_88703482 0.38 ENSMUST00000043087.15
ENSMUST00000162183.8
asparagine-linked glycosylation 12 (alpha-1,6-mannosyltransferase)
chr2_+_129434738 0.38 ENSMUST00000153491.8
ENSMUST00000161620.8
ENSMUST00000179001.8
signal-regulatory protein alpha
chr19_+_8897732 0.38 ENSMUST00000096243.7
beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr8_+_72914966 0.38 ENSMUST00000003121.9
RAB8A, member RAS oncogene family
chr2_-_160714904 0.38 ENSMUST00000109460.8
ENSMUST00000127201.2
zinc fingers and homeoboxes 3
chr9_+_110947167 0.38 ENSMUST00000035078.13
ENSMUST00000196981.5
ENSMUST00000098340.7
leucine rich repeat (in FLII) interacting protein 2
chr11_+_117545037 0.38 ENSMUST00000026658.13
trinucleotide repeat containing 6C
chr2_+_61423469 0.38 ENSMUST00000112494.2
TRAF family member-associated Nf-kappa B activator
chr2_+_129434834 0.37 ENSMUST00000103203.8
signal-regulatory protein alpha
chr8_+_110505494 0.37 ENSMUST00000034171.9
adaptor protein complex AP-1, gamma 1 subunit
chr19_-_7183596 0.37 ENSMUST00000123594.8
OTU domain, ubiquitin aldehyde binding 1
chr3_+_96484294 0.37 ENSMUST00000148290.2
predicted gene 16253
chr14_+_20724378 0.37 ENSMUST00000224492.2
ENSMUST00000223751.2
ENSMUST00000225108.2
ENSMUST00000224754.2
Sec24 related gene family, member C (S. cerevisiae)
chr9_+_65816206 0.37 ENSMUST00000205379.2
ENSMUST00000206048.2
ENSMUST00000034949.10
ENSMUST00000154589.2
casein kinase 1, gamma 1
chr2_+_121287444 0.36 ENSMUST00000126764.2
huntingtin interacting protein K
chr19_+_6097083 0.36 ENSMUST00000134667.8
synovial apoptosis inhibitor 1, synoviolin
chr11_-_115968745 0.36 ENSMUST00000156545.2
ENSMUST00000075036.9
ENSMUST00000106451.8
unc-13 homolog D
chr7_-_25418401 0.36 ENSMUST00000125699.3
ENSMUST00000002683.3
coiled-coil domain containing 97
chr2_+_61423421 0.36 ENSMUST00000112495.8
ENSMUST00000112501.9
TRAF family member-associated Nf-kappa B activator
chr11_-_83189670 0.35 ENSMUST00000175741.8
ENSMUST00000176518.2
peroxisomal biogenesis factor 12
chr15_-_76079891 0.35 ENSMUST00000023226.13
plectin
chr2_+_14078958 0.35 ENSMUST00000028050.14
signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
chr7_-_73187369 0.35 ENSMUST00000172704.6
chromodomain helicase DNA binding protein 2
chr11_-_83189734 0.35 ENSMUST00000108146.8
ENSMUST00000136369.2
ENSMUST00000018877.9
peroxisomal biogenesis factor 12
chr6_+_29467717 0.34 ENSMUST00000004396.13
ATPase, H+ transporting, lysosomal V1 subunit F
chr9_+_27210500 0.34 ENSMUST00000214357.2
ENSMUST00000115247.8
ENSMUST00000133213.3
immunoglobulin superfamily, member 9B
chr11_+_105866030 0.33 ENSMUST00000001964.8
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
chr12_+_11316101 0.33 ENSMUST00000218866.2
structural maintenance of chromosomes 6
chr5_+_122534900 0.33 ENSMUST00000196969.5
actin related protein 2/3 complex, subunit 3
chr11_+_101144533 0.33 ENSMUST00000007533.15
ENSMUST00000042477.13
ENSMUST00000100414.12
ENSMUST00000107280.11
ENSMUST00000121331.2
vacuolar protein sorting 25
chr11_+_69214971 0.33 ENSMUST00000108662.2
trafficking protein particle complex 1
chr7_-_28071658 0.33 ENSMUST00000094644.11
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr13_-_18118736 0.33 ENSMUST00000009003.9
v-ral simian leukemia viral oncogene A (ras related)
chr17_-_34159273 0.33 ENSMUST00000179418.9
ENSMUST00000174048.8
ENSMUST00000174426.2
ENSMUST00000173678.3
ENSMUST00000025163.14
prefoldin subunit 6
chr18_+_34994253 0.32 ENSMUST00000165033.2
early growth response 1
chr3_+_27992787 0.32 ENSMUST00000120834.8
phospholipase D1
chr2_-_92290791 0.32 ENSMUST00000125276.2
solute carrier family 35, member C1
chr11_+_117545618 0.32 ENSMUST00000106344.8
trinucleotide repeat containing 6C
chr2_-_181333597 0.32 ENSMUST00000108778.8
ENSMUST00000165416.8
regulator of G-protein signaling 19
chr5_+_143803540 0.32 ENSMUST00000100487.6
eukaryotic translation initiation factor 2 alpha kinase 1
chr5_+_115680964 0.32 ENSMUST00000137716.8
paxillin
chr7_+_126528016 0.32 ENSMUST00000032924.6
potassium channel tetramerisation domain containing 13
chr4_-_149569659 0.32 ENSMUST00000119921.8
nicotinamide nucleotide adenylyltransferase 1
chr12_-_84408576 0.30 ENSMUST00000021659.2
ENSMUST00000065536.9
family with sequence similarity 161, member B
chr11_-_4110286 0.30 ENSMUST00000093381.11
ENSMUST00000101626.9
coiled-coil domain containing 157
chr13_-_42000958 0.30 ENSMUST00000072012.10
androgen dependent TFPI regulating protein
chr7_-_30262512 0.30 ENSMUST00000207747.2
ENSMUST00000207797.2
presenilin enhancer gamma secretase subunit
chr17_-_29226886 0.29 ENSMUST00000232723.2
serine/threonine kinase 38
chr7_-_84339156 0.29 ENSMUST00000209117.2
ENSMUST00000207975.2
zinc finger, AN1-type domain 6
chr18_-_60981981 0.29 ENSMUST00000177172.8
ENSMUST00000175934.8
ENSMUST00000176630.8
treacle ribosome biogenesis factor 1
chr5_+_138083345 0.29 ENSMUST00000019660.11
ENSMUST00000066617.12
ENSMUST00000110963.8
zinc finger with KRAB and SCAN domains 1
chr4_+_44756553 0.28 ENSMUST00000107824.9
zinc finger, CCHC domain containing 7
chr17_-_57554631 0.28 ENSMUST00000233568.2
ENSMUST00000005975.8
G protein-coupled receptor 108
chr2_+_152511381 0.28 ENSMUST00000125366.8
ENSMUST00000109825.8
ENSMUST00000089059.9
ENSMUST00000079247.4
histocompatibility 13
chr2_-_73216743 0.28 ENSMUST00000112044.8
ENSMUST00000112043.8
ENSMUST00000076463.12
G protein-coupled receptor 155
chr7_-_16020668 0.28 ENSMUST00000150528.9
ENSMUST00000118976.9
ENSMUST00000146609.3
coiled-coil domain containing 9
chr5_-_100126707 0.28 ENSMUST00000170912.2
heterogeneous nuclear ribonucleoprotein D
chr8_-_70962972 0.28 ENSMUST00000140679.8
ENSMUST00000129909.8
ENSMUST00000081940.11
ubiquitin A-52 residue ribosomal protein fusion product 1
chr14_-_65335479 0.27 ENSMUST00000225633.2
ENSMUST00000022550.8
exostosin-like glycosyltransferase 3
chr10_-_30531768 0.27 ENSMUST00000092610.12
nuclear receptor coactivator 7
chr7_-_6158925 0.27 ENSMUST00000207957.2
ENSMUST00000094870.3
ENSMUST00000207628.2
zinc finger protein 787
chr18_+_35860019 0.27 ENSMUST00000097617.3
RIKEN cDNA 1700066B19 gene
chr11_+_69214883 0.27 ENSMUST00000102601.10
trafficking protein particle complex 1
chr9_+_65816370 0.27 ENSMUST00000206594.2
casein kinase 1, gamma 1
chr18_-_46730381 0.26 ENSMUST00000036030.14
transmembrane p24 trafficking protein 7
chr18_-_73836810 0.26 ENSMUST00000025393.14
SMAD family member 4
chrX_-_7956682 0.26 ENSMUST00000033505.7
Wiskott-Aldrich syndrome
chr2_-_167334746 0.25 ENSMUST00000109211.9
ENSMUST00000057627.16
spermatogenesis associated 2
chr5_-_69749617 0.25 ENSMUST00000173927.8
ENSMUST00000120789.8
ENSMUST00000031117.13
glucosamine-6-phosphate deaminase 2
chr11_+_68393845 0.25 ENSMUST00000102613.8
ENSMUST00000060441.7
phosphoinositide-3-kinase regulatory subunit 5
chr1_-_13660027 0.25 ENSMUST00000027068.11
translocating chain-associating membrane protein 1
chr17_-_36290129 0.25 ENSMUST00000165613.9
ENSMUST00000173872.8
proline-rich polypeptide 3
chr2_+_25132941 0.25 ENSMUST00000114355.2
ENSMUST00000060818.2
ring finger protein 208
chr2_-_26335187 0.25 ENSMUST00000114082.9
ENSMUST00000091252.5
SEC16 homolog A, endoplasmic reticulum export factor
chr4_-_137084973 0.25 ENSMUST00000030417.10
ENSMUST00000051477.13
cell division cycle 42
chr1_+_39406897 0.25 ENSMUST00000086535.12
ribosomal protein L31
chr10_+_77458197 0.25 ENSMUST00000172772.2
ubiquitin-conjugating enzyme E2G 2
chrX_+_41591355 0.24 ENSMUST00000189753.7
SH2 domain containing 1A
chr17_+_32725420 0.24 ENSMUST00000235238.2
ENSMUST00000165999.2
cytochrome P450, family 4, subfamily f, polypeptide 17
chr17_+_35354430 0.24 ENSMUST00000173535.8
ENSMUST00000173952.8
BCL2-associated athanogene 6
chr7_+_140808680 0.24 ENSMUST00000106027.9
PHD and ring finger domains 1
chr4_-_152533265 0.24 ENSMUST00000159840.8
ENSMUST00000105648.10
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr18_-_24254865 0.24 ENSMUST00000055012.12
ENSMUST00000153360.8
ENSMUST00000141489.2
INO80 complex subunit C
chr11_-_58221145 0.24 ENSMUST00000186859.2
ENSMUST00000065533.3
zinc finger protein 672
chr11_-_83193412 0.24 ENSMUST00000176374.2
peroxisomal biogenesis factor 12
chr8_-_65582206 0.23 ENSMUST00000098713.5
small integral membrane protein 31
chr7_-_141241632 0.23 ENSMUST00000239500.1
mucin 6, gastric
chr18_-_10610332 0.23 ENSMUST00000025142.13
establishment of sister chromatid cohesion N-acetyltransferase 1
chr6_+_35229628 0.23 ENSMUST00000130875.8
RIKEN cDNA 1810058I24 gene
chr8_+_121854566 0.23 ENSMUST00000181609.2
forkhead box L1
chr7_-_28071919 0.23 ENSMUST00000119990.8
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr19_-_9876815 0.23 ENSMUST00000237147.2
ENSMUST00000025562.9
inner centromere protein
chrX_+_74460234 0.23 ENSMUST00000033544.14
BRCA1/BRCA2-containing complex, subunit 3
chr15_+_35371644 0.23 ENSMUST00000227455.2
vacuolar protein sorting 13B
chr2_-_22930149 0.22 ENSMUST00000091394.13
ENSMUST00000093171.13
abl interactor 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Spdef

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0019085 early viral transcription(GO:0019085)
0.3 1.4 GO:2000397 regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.3 1.3 GO:0035801 adrenal cortex development(GO:0035801) adrenal cortex formation(GO:0035802)
0.3 0.3 GO:0072301 regulation of metanephric glomerular mesangial cell proliferation(GO:0072301)
0.3 1.5 GO:0044565 dendritic cell proliferation(GO:0044565)
0.3 0.8 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.2 1.0 GO:0071336 regulation of hair follicle cell proliferation(GO:0071336)
0.2 0.7 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 1.0 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 0.6 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
0.1 0.5 GO:1902363 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.1 0.3 GO:2000170 positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
0.1 0.3 GO:0043323 positive regulation of natural killer cell degranulation(GO:0043323)
0.1 1.0 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.1 0.5 GO:0002432 granuloma formation(GO:0002432)
0.1 0.7 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 0.3 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.1 0.4 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.1 0.8 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 0.3 GO:0003220 left ventricular cardiac muscle tissue morphogenesis(GO:0003220) brainstem development(GO:0003360) positive regulation of luteinizing hormone secretion(GO:0033686) nephrogenic mesenchyme development(GO:0072076) cell proliferation involved in heart valve development(GO:2000793)
0.1 0.3 GO:0002625 regulation of T cell antigen processing and presentation(GO:0002625)
0.1 2.5 GO:0045116 protein neddylation(GO:0045116)
0.1 0.4 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.1 0.4 GO:0035660 MyD88-dependent toll-like receptor 4 signaling pathway(GO:0035660)
0.1 0.4 GO:0070433 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433)
0.1 0.4 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.1 0.3 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.1 0.2 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.1 0.2 GO:2000845 positive regulation of testosterone secretion(GO:2000845)
0.1 0.3 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.1 0.3 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.1 0.6 GO:0014029 neural crest formation(GO:0014029)
0.1 0.2 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.1 0.2 GO:0071846 actin filament debranching(GO:0071846)
0.1 0.3 GO:1901355 response to rapamycin(GO:1901355)
0.1 1.2 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.1 1.7 GO:0031424 keratinization(GO:0031424)
0.1 1.0 GO:0045779 negative regulation of bone resorption(GO:0045779)
0.0 0.1 GO:0072720 response to sorbitol(GO:0072708) response to dithiothreitol(GO:0072720)
0.0 0.9 GO:0007343 egg activation(GO:0007343) negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.2 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0 1.4 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.1 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.0 0.8 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:2000556 regulation of T-helper 1 cell cytokine production(GO:2000554) positive regulation of T-helper 1 cell cytokine production(GO:2000556)
0.0 0.7 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.2 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 0.6 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.6 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.3 GO:0036508 protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) protein demannosylation(GO:0036507) protein alpha-1,2-demannosylation(GO:0036508) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
0.0 0.2 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.7 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0 0.5 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)
0.0 0.2 GO:0036506 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.0 0.5 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 1.0 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.3 GO:1903551 regulation of extracellular exosome assembly(GO:1903551)
0.0 0.1 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.0 0.2 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.5 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.0 0.3 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151)
0.0 0.3 GO:0051665 membrane raft localization(GO:0051665)
0.0 0.1 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.0 0.2 GO:0051106 regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
0.0 0.6 GO:0033327 male sex determination(GO:0030238) Leydig cell differentiation(GO:0033327)
0.0 0.5 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0 0.2 GO:0070163 adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163)
0.0 1.7 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 1.2 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.3 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 1.0 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.3 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.2 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.4 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.7 GO:0071801 regulation of podosome assembly(GO:0071801)
0.0 0.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) regulation of peptidyl-cysteine S-nitrosylation(GO:2000169)
0.0 0.1 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.0 0.1 GO:1902277 negative regulation of pancreatic amylase secretion(GO:1902277)
0.0 0.4 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.2 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.0 0.3 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.1 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.0 0.5 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.2 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.4 GO:1903540 neurotransmitter receptor transport to postsynaptic membrane(GO:0098969) establishment of protein localization to postsynaptic membrane(GO:1903540)
0.0 0.8 GO:0010996 response to auditory stimulus(GO:0010996)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.5 GO:0072663 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.4 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.0 0.1 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.2 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.7 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.3 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.2 GO:0009048 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.4 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.2 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.2 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.9 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.5 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.5 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.1 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.0 1.3 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.3 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.2 GO:0060352 cell adhesion molecule production(GO:0060352)
0.0 0.2 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.2 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.0 0.0 GO:2000321 positive regulation of T-helper 17 cell differentiation(GO:2000321)
0.0 0.2 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.2 0.9 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.1 0.4 GO:1990031 pinceau fiber(GO:1990031)
0.1 0.6 GO:0044316 cone cell pedicle(GO:0044316)
0.1 1.4 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.5 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.1 0.3 GO:0035061 interchromatin granule(GO:0035061)
0.1 0.6 GO:0070847 core mediator complex(GO:0070847)
0.1 0.8 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 1.0 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 0.5 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 1.2 GO:0030008 TRAPP complex(GO:0030008)
0.1 0.3 GO:0032444 activin responsive factor complex(GO:0032444)
0.1 1.7 GO:0001533 cornified envelope(GO:0001533)
0.1 0.3 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 0.5 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.4 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.5 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 1.0 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 1.8 GO:0043034 costamere(GO:0043034)
0.0 0.2 GO:0044393 microspike(GO:0044393)
0.0 0.3 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.6 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.2 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.1 GO:0035101 FACT complex(GO:0035101)
0.0 0.4 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.7 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.8 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.5 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.4 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0000814 ESCRT II complex(GO:0000814)
0.0 0.2 GO:0070552 BRISC complex(GO:0070552)
0.0 0.1 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.6 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.7 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.2 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.0 0.3 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.3 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.5 GO:0005719 nuclear euchromatin(GO:0005719)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.2 0.7 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.2 1.7 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.6 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.1 0.9 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 2.0 GO:0031386 protein tag(GO:0031386)
0.1 0.5 GO:0051435 BH4 domain binding(GO:0051435)
0.1 0.3 GO:0031753 endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755)
0.1 1.4 GO:0046790 virion binding(GO:0046790)
0.1 0.3 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.1 1.7 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.1 0.3 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.1 1.3 GO:0050693 LBD domain binding(GO:0050693)
0.1 0.3 GO:0031711 bradykinin receptor binding(GO:0031711)
0.1 0.3 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 0.8 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 1.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 0.4 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 0.3 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.1 0.4 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 0.2 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.1 2.8 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.5 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.4 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.3 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.0 0.8 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.2 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.3 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.7 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 1.0 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.3 GO:0043199 sulfate binding(GO:0043199)
0.0 0.1 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.0 0.7 GO:0070513 death domain binding(GO:0070513)
0.0 0.8 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.4 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.3 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.2 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.1 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.3 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.3 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.2 GO:0051425 inositol bisphosphate phosphatase activity(GO:0016312) PTB domain binding(GO:0051425)
0.0 0.7 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.2 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.4 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.2 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.4 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.2 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 1.0 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 1.0 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.4 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.0 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.1 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.4 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:0070004 cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004)
0.0 0.5 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.0 GO:0086059 voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059)
0.0 0.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.6 GO:0030552 cAMP binding(GO:0030552)
0.0 0.0 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.4 GO:0030506 ankyrin binding(GO:0030506)
0.0 1.9 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.2 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.4 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 1.1 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.3 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.7 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 1.4 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.6 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.3 PID ALK2 PATHWAY ALK2 signaling events
0.0 1.0 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.4 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.4 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 1.1 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.3 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.2 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.7 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.5 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 0.2 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 1.0 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.5 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.8 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.7 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 1.8 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.4 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.9 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.5 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.8 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.3 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.7 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.7 REACTOME KINESINS Genes involved in Kinesins
0.0 0.4 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.3 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.6 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.3 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.5 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.1 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.2 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling