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avrg: GFI1 WT vs 36n/n vs KD

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Results for Spi1

Z-value: 1.16

Motif logo

Transcription factors associated with Spi1

Gene Symbol Gene ID Gene Info
ENSMUSG00000002111.9 spleen focus forming virus (SFFV) proviral integration oncogene

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Spi1mm39_v1_chr2_+_90927053_909272150.128.5e-01Click!

Activity profile of Spi1 motif

Sorted Z-values of Spi1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_20296337 0.70 ENSMUST00000001921.3
carboxypeptidase A3, mast cell
chr2_+_84810802 0.68 ENSMUST00000028467.6
proteoglycan 2, bone marrow
chr2_+_84818538 0.64 ENSMUST00000028466.12
proteoglycan 3
chr3_+_54268523 0.52 ENSMUST00000117373.8
ENSMUST00000107985.10
ENSMUST00000073012.13
ENSMUST00000081564.13
periostin, osteoblast specific factor
chr5_-_107873883 0.51 ENSMUST00000159263.3
growth factor independent 1 transcription repressor
chr2_+_129854256 0.44 ENSMUST00000110299.3
transglutaminase 3, E polypeptide
chr4_-_154721288 0.36 ENSMUST00000030902.13
ENSMUST00000105637.8
ENSMUST00000070313.14
ENSMUST00000105636.8
ENSMUST00000105638.9
ENSMUST00000097759.9
ENSMUST00000124771.2
PR domain containing 16
chr11_-_83540175 0.33 ENSMUST00000001008.6
chemokine (C-C motif) ligand 3
chr6_-_52217821 0.32 ENSMUST00000121043.2
homeobox A10
chr7_-_19043955 0.30 ENSMUST00000207334.2
ENSMUST00000208505.2
ENSMUST00000207716.2
ENSMUST00000208326.2
ENSMUST00000003640.4
FBJ osteosarcoma oncogene B
chr9_-_43151179 0.30 ENSMUST00000034512.7
out at first homolog
chr11_-_51748450 0.28 ENSMUST00000020655.14
ENSMUST00000109090.8
jade family PHD finger 2
chr13_-_23806530 0.28 ENSMUST00000062045.4
H1.4 linker histone, cluster member
chr11_-_102360664 0.28 ENSMUST00000103086.4
integrin alpha 2b
chr4_+_54947976 0.27 ENSMUST00000098070.10
zinc finger protein 462
chr17_+_34809132 0.27 ENSMUST00000173772.2
G-protein signalling modulator 3 (AGS3-like, C. elegans)
chr7_-_99512558 0.27 ENSMUST00000207137.2
ENSMUST00000207063.2
ENSMUST00000207580.2
signal peptidase complex subunit 2 homolog (S. cerevisiae)
chr19_-_33567708 0.26 ENSMUST00000112508.9
lipase, member O3
chr18_-_36859732 0.26 ENSMUST00000061829.8
CD14 antigen
chr1_-_69723316 0.26 ENSMUST00000190855.7
ENSMUST00000188110.7
ENSMUST00000191262.7
IKAROS family zinc finger 2
chr19_+_32597379 0.25 ENSMUST00000236290.2
ENSMUST00000025833.7
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr2_+_68966125 0.25 ENSMUST00000041865.8
nitric oxide synthase trafficker
chr18_+_61178211 0.25 ENSMUST00000025522.11
ENSMUST00000115274.2
platelet derived growth factor receptor, beta polypeptide
chr14_-_64654397 0.24 ENSMUST00000210428.2
methionine sulfoxide reductase A
chr1_+_194621127 0.24 ENSMUST00000016638.8
ENSMUST00000110815.9
CD34 antigen
chr2_+_80145805 0.23 ENSMUST00000028392.8
DnaJ heat shock protein family (Hsp40) member C10
chr13_-_110493665 0.23 ENSMUST00000058806.7
ENSMUST00000224534.2
Grb2-binding adaptor, transmembrane
chr19_+_4036562 0.23 ENSMUST00000236224.2
ENSMUST00000236510.2
ENSMUST00000237910.2
ENSMUST00000235612.2
ENSMUST00000054030.8
aspartoacylase (aminoacylase) 3
chr2_+_152468850 0.23 ENSMUST00000000369.4
ENSMUST00000150913.2
rad and gem related GTP binding protein 1
chr11_+_83594817 0.23 ENSMUST00000092836.6
WAP four-disulfide core domain 17
chr17_+_56312672 0.22 ENSMUST00000133998.8
MPN domain containing
chrM_+_7006 0.22 ENSMUST00000082405.1
mitochondrially encoded cytochrome c oxidase II
chr5_+_31070739 0.22 ENSMUST00000031055.8
elastin microfibril interfacer 1
chr11_-_83469446 0.22 ENSMUST00000019266.6
chemokine (C-C motif) ligand 9
chr9_+_66033893 0.22 ENSMUST00000034945.6
cytosolic iron-sulfur assembly component 2A
chr18_+_84106188 0.21 ENSMUST00000060223.4
zinc binding alcohol dehydrogenase, domain containing 2
chr6_+_134012602 0.21 ENSMUST00000081028.13
ENSMUST00000111963.8
ets variant 6
chr13_-_104057016 0.21 ENSMUST00000022222.12
Erbb2 interacting protein
chr2_+_158148413 0.20 ENSMUST00000109491.8
ENSMUST00000016168.9
lipopolysaccharide binding protein
chr17_+_35200823 0.20 ENSMUST00000114011.11
LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated
chr19_-_33739351 0.20 ENSMUST00000025694.7
lipase, member O3
chr7_-_101513300 0.20 ENSMUST00000106981.8
folate receptor 1 (adult)
chr14_-_64654592 0.19 ENSMUST00000210363.2
methionine sulfoxide reductase A
chr4_+_129229805 0.19 ENSMUST00000119480.2
zinc finger and BTB domain containing 8 opposite strand
chr7_-_101899294 0.19 ENSMUST00000106923.2
ENSMUST00000098230.11
ras homolog family member G
chrX_+_106193167 0.19 ENSMUST00000137107.2
ENSMUST00000067249.3
purinergic receptor P2Y, G-protein coupled 10B
chr17_+_34808772 0.19 ENSMUST00000038244.15
G-protein signalling modulator 3 (AGS3-like, C. elegans)
chr3_+_95434093 0.19 ENSMUST00000015667.9
ENSMUST00000116304.3
cathepsin S
chr14_-_70396859 0.19 ENSMUST00000058240.14
ENSMUST00000153871.2
RIKEN cDNA 9930012K11 gene
chr1_+_43484895 0.19 ENSMUST00000086421.9
non-catalytic region of tyrosine kinase adaptor protein 2
chr11_+_68858942 0.19 ENSMUST00000102606.10
ENSMUST00000018884.6
solute carrier family 25, member 35
chr6_-_16898440 0.18 ENSMUST00000031533.11
transcription factor EC
chr9_+_122752116 0.18 ENSMUST00000051667.14
zinc finger protein 105
chr9_+_74945021 0.18 ENSMUST00000168301.2
cAMP-regulated phosphoprotein 19
chr5_+_52521133 0.18 ENSMUST00000101208.6
superoxide dismutase 3, extracellular
chr2_+_164782642 0.18 ENSMUST00000137626.2
matrix metallopeptidase 9
chr14_-_79539063 0.18 ENSMUST00000022595.8
regulator of cell cycle
chr9_-_75448979 0.18 ENSMUST00000214171.2
tropomodulin 3
chr5_+_122529941 0.18 ENSMUST00000102525.11
actin related protein 2/3 complex, subunit 3
chr13_+_23922783 0.18 ENSMUST00000040914.3
H1.2 linker histone, cluster member
chr6_+_4003904 0.17 ENSMUST00000031670.10
guanine nucleotide binding protein (G protein), gamma 11
chr15_-_66432938 0.17 ENSMUST00000048372.7
transmembrane protein 71
chr6_+_88442391 0.17 ENSMUST00000032165.16
RuvB-like protein 1
chr17_+_79359617 0.17 ENSMUST00000233916.2
glutaminyl-peptide cyclotransferase (glutaminyl cyclase)
chr8_+_95703728 0.17 ENSMUST00000179619.9
adhesion G protein-coupled receptor G1
chr11_+_108811168 0.17 ENSMUST00000052915.14
axin 2
chr1_-_131204651 0.17 ENSMUST00000161764.8
inhibitor of kappaB kinase epsilon
chr1_-_171122509 0.17 ENSMUST00000111302.4
ENSMUST00000080001.9
ubiquitin-fold modifier conjugating enzyme 1
chr17_+_29487881 0.17 ENSMUST00000234845.2
ENSMUST00000235038.2
ENSMUST00000235050.2
ENSMUST00000120346.9
ENSMUST00000234377.2
ENSMUST00000235074.2
ENSMUST00000235040.2
ENSMUST00000234256.2
ENSMUST00000234459.2
cDNA sequence BC004004
chr8_+_47986674 0.16 ENSMUST00000033973.14
ENSMUST00000176379.2
RWD domain containing 4A
chr3_-_51184895 0.16 ENSMUST00000108051.8
ENSMUST00000108053.9
E74-like factor 2
chr6_-_136918844 0.16 ENSMUST00000204934.2
Rho, GDP dissociation inhibitor (GDI) beta
chr9_-_22042930 0.16 ENSMUST00000213815.2
acid phosphatase 5, tartrate resistant
chr1_+_88022776 0.16 ENSMUST00000150634.8
ENSMUST00000058237.14
UDP glucuronosyltransferase 1 family, polypeptide A7C
chr7_+_105289655 0.16 ENSMUST00000058333.10
translocase of inner mitochondrial membrane 10B
chr19_+_24853039 0.16 ENSMUST00000073080.7
predicted gene 10053
chr18_+_34994253 0.16 ENSMUST00000165033.2
early growth response 1
chr19_+_4282040 0.16 ENSMUST00000237518.2
polymerase (DNA-directed), delta 4
chr6_+_135339543 0.16 ENSMUST00000205156.3
epithelial membrane protein 1
chr13_-_104056803 0.16 ENSMUST00000091269.11
ENSMUST00000188997.7
ENSMUST00000169083.8
ENSMUST00000191275.7
Erbb2 interacting protein
chr3_-_131138541 0.16 ENSMUST00000090246.5
ENSMUST00000126569.2
sphingomyelin synthase 2
chr11_-_98436626 0.16 ENSMUST00000103141.4
IKAROS family zinc finger 3
chr13_-_55676334 0.16 ENSMUST00000047877.5
docking protein 3
chr5_+_102629365 0.16 ENSMUST00000112854.8
Rho GTPase activating protein 24
chr5_+_102629240 0.16 ENSMUST00000073302.12
ENSMUST00000094559.9
Rho GTPase activating protein 24
chr8_-_106022676 0.16 ENSMUST00000057855.4
exocyst complex component 3-like
chrX_+_106193060 0.16 ENSMUST00000125676.8
ENSMUST00000180182.2
purinergic receptor P2Y, G-protein coupled 10B
chr5_-_124003553 0.16 ENSMUST00000057145.7
hydroxycarboxylic acid receptor 2
chr11_-_78875689 0.15 ENSMUST00000108269.10
ENSMUST00000108268.10
lectin, galactose binding, soluble 9
chr16_-_75706161 0.15 ENSMUST00000114239.9
SAM domain, SH3 domain and nuclear localization signals, 1
chrX_+_36059274 0.15 ENSMUST00000016463.4
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5
chr12_+_75355082 0.15 ENSMUST00000118602.8
ENSMUST00000118966.8
ENSMUST00000055390.6
ras homolog family member J
chr9_+_58160447 0.15 ENSMUST00000034883.7
stomatin-like 1
chr11_+_108316018 0.15 ENSMUST00000150863.9
ENSMUST00000061287.12
ENSMUST00000149683.9
centrosomal protein 112
chr17_+_47201552 0.15 ENSMUST00000040434.9
tubulin-specific chaperone C
chr11_-_78875657 0.15 ENSMUST00000073001.5
lectin, galactose binding, soluble 9
chr14_-_56339915 0.15 ENSMUST00000015583.2
cathepsin G
chr10_-_111829393 0.15 ENSMUST00000161870.3
GLI pathogenesis-related 1 (glioma)
chr11_-_83483807 0.15 ENSMUST00000019071.4
chemokine (C-C motif) ligand 6
chr11_-_93859064 0.15 ENSMUST00000107844.3
ENSMUST00000170303.2
NME/NM23 nucleoside diphosphate kinase 1
predicted gene 20390
chr14_-_52248324 0.15 ENSMUST00000226964.2
zinc finger protein 219
chr17_+_43978377 0.15 ENSMUST00000233627.2
ENSMUST00000233437.2
cytochrome P450, family 39, subfamily a, polypeptide 1
chr3_+_89110223 0.15 ENSMUST00000077367.11
ENSMUST00000167998.2
glucosidase, beta, acid
chr9_+_122752164 0.15 ENSMUST00000148851.2
zinc finger protein 105
chr15_-_74855264 0.14 ENSMUST00000023250.11
ENSMUST00000166694.2
lymphocyte antigen 6 complex, locus I
chr7_+_46445512 0.14 ENSMUST00000006774.11
ENSMUST00000165031.8
general transcription factor II H, polypeptide 1
chr11_+_96209093 0.14 ENSMUST00000049241.9
homeobox B4
chrX_+_133501928 0.14 ENSMUST00000074950.11
ENSMUST00000113203.2
ENSMUST00000113202.8
ENSMUST00000050331.13
ENSMUST00000059297.6
heterogeneous nuclear ribonucleoprotein H2
chr19_+_53891802 0.14 ENSMUST00000165617.3
programmed cell death 4
chr9_+_107828136 0.14 ENSMUST00000049348.9
ENSMUST00000194271.2
TRAF-interacting protein
chr11_-_99276868 0.14 ENSMUST00000211768.2
keratin 10
chrX_-_69520778 0.14 ENSMUST00000101506.10
ENSMUST00000114630.3
transmembrane protein 185A
chr15_-_37007623 0.14 ENSMUST00000078976.9
zinc finger protein 706
chr17_+_7437500 0.14 ENSMUST00000024575.8
ribosomal protein S6 kinase, polypeptide 2
chr18_-_35841435 0.14 ENSMUST00000236738.2
ENSMUST00000237995.2
DnaJ heat shock protein family (Hsp40) member C18
chr3_-_107876477 0.14 ENSMUST00000004136.10
glutathione S-transferase, mu 3
chr3_-_106697459 0.14 ENSMUST00000038845.10
CD53 antigen
chr3_+_151143524 0.14 ENSMUST00000046977.12
adhesion G protein-coupled receptor L4
chr17_+_27276262 0.14 ENSMUST00000049308.9
inositol 1,4,5-triphosphate receptor 3
chr8_-_41870077 0.14 ENSMUST00000033999.8
FSHD region gene 1
chr14_+_56003406 0.14 ENSMUST00000057569.4
leukotriene B4 receptor 1
chr17_-_35420972 0.14 ENSMUST00000167924.2
ENSMUST00000025263.15
tumor necrosis factor
chr15_-_63932176 0.14 ENSMUST00000226675.2
ENSMUST00000228226.2
ENSMUST00000227024.2
CYFIP related Rac1 interactor B
chr6_+_138117519 0.14 ENSMUST00000120939.8
ENSMUST00000204628.3
ENSMUST00000140932.2
ENSMUST00000120302.8
microsomal glutathione S-transferase 1
chr15_+_74828272 0.14 ENSMUST00000188042.2
lymphocyte antigen 6 complex, locus E
chr8_-_72175949 0.14 ENSMUST00000125092.2
FCH domain only 1
chr17_+_74796473 0.14 ENSMUST00000024873.7
Yip1 domain family, member 4
chr19_+_11747721 0.14 ENSMUST00000167199.3
mitochondrial ribosomal protein L16
chr1_-_71692320 0.14 ENSMUST00000186940.7
ENSMUST00000188894.7
ENSMUST00000188674.7
ENSMUST00000189821.7
ENSMUST00000187938.7
ENSMUST00000190780.7
ENSMUST00000186736.2
ENSMUST00000055226.13
ENSMUST00000186129.7
fibronectin 1
chr17_+_29487762 0.13 ENSMUST00000064709.13
ENSMUST00000234711.2
cDNA sequence BC004004
chr4_+_133311665 0.13 ENSMUST00000030661.14
ENSMUST00000105899.2
GPN-loop GTPase 2
chr19_-_18609118 0.13 ENSMUST00000025631.7
ENSMUST00000236615.2
osteoclast stimulating factor 1
chr6_+_124807176 0.13 ENSMUST00000131847.8
ENSMUST00000151674.3
cell division cycle associated 3
chr5_+_24598633 0.13 ENSMUST00000138168.3
ENSMUST00000115077.8
ATP-binding cassette, sub-family B (MDR/TAP), member 8
chr6_-_136918671 0.13 ENSMUST00000032344.12
Rho, GDP dissociation inhibitor (GDI) beta
chr6_-_124689001 0.13 ENSMUST00000203238.2
EMG1 N1-specific pseudouridine methyltransferase
chr7_+_79910948 0.13 ENSMUST00000117989.2
neugrin, neurite outgrowth associated
chr11_+_98441923 0.13 ENSMUST00000081033.13
ENSMUST00000107511.8
ENSMUST00000107509.8
ENSMUST00000017339.12
zona pellucida binding protein 2
chr6_-_72367642 0.13 ENSMUST00000059983.10
vesicle-associated membrane protein 8
chr4_-_133599616 0.13 ENSMUST00000157067.9
ribosomal protein S6 kinase polypeptide 1
chr15_+_78128990 0.13 ENSMUST00000096357.12
neutrophil cytosolic factor 4
chr9_+_74945101 0.13 ENSMUST00000167885.8
ENSMUST00000169188.2
cAMP-regulated phosphoprotein 19
chr5_+_16758538 0.13 ENSMUST00000199581.5
hepatocyte growth factor
chr11_-_69556904 0.13 ENSMUST00000018918.12
CD68 antigen
chr19_+_32573182 0.13 ENSMUST00000235594.2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chrX_+_133486391 0.13 ENSMUST00000113211.8
ribosomal protein L36A
chr6_-_67014383 0.13 ENSMUST00000043098.9
growth arrest and DNA-damage-inducible 45 alpha
chr7_-_140596811 0.13 ENSMUST00000081924.5
interferon induced transmembrane protein 6
chr3_-_87676239 0.13 ENSMUST00000173184.2
ENSMUST00000172621.8
ENSMUST00000174759.8
ENSMUST00000172590.8
ENSMUST00000079083.12
platelet endothelial aggregation receptor 1
chr5_+_16758777 0.13 ENSMUST00000030683.8
hepatocyte growth factor
chr2_-_155571279 0.13 ENSMUST00000040833.5
ER degradation enhancer, mannosidase alpha-like 2
chr9_+_72946994 0.13 ENSMUST00000184126.3
Pigb opposite strand 1
chr4_-_133695264 0.13 ENSMUST00000102553.11
high mobility group nucleosomal binding domain 2
chr18_+_67338437 0.13 ENSMUST00000210564.3
charged multivesicular body protein 1B
chr4_+_119052693 0.13 ENSMUST00000097908.4
small vasohibin binding protein
chr8_+_26275560 0.13 ENSMUST00000211168.2
LSM1 homolog, mRNA degradation associated
chr4_+_45890303 0.13 ENSMUST00000178561.8
coiled-coil domain containing 180
chr6_+_117894242 0.13 ENSMUST00000180020.8
ENSMUST00000177570.2
heterogeneous nuclear ribonucleoprotein F
chr1_+_152683627 0.13 ENSMUST00000027754.7
neutrophil cytosolic factor 2
chr9_-_107419309 0.13 ENSMUST00000195235.6
cytochrome b-561 domain containing 2
chr19_+_4282487 0.13 ENSMUST00000235306.2
polymerase (DNA-directed), delta 4
chr8_+_85807566 0.13 ENSMUST00000140621.2
WD repeat domain 83 opposite strand
chr15_-_83054369 0.13 ENSMUST00000162834.3
cytochrome b5 reductase 3
chr19_+_6214416 0.13 ENSMUST00000045042.8
ENSMUST00000237511.2
basic leucine zipper transcription factor, ATF-like 2
chr8_-_47986473 0.13 ENSMUST00000039061.15
trafficking protein particle complex 11
chr18_-_43610829 0.13 ENSMUST00000057110.11
eukaryotic translation initiation factor 3, subunit J2
chr9_+_74944896 0.13 ENSMUST00000168166.8
ENSMUST00000169492.8
ENSMUST00000170308.8
cAMP-regulated phosphoprotein 19
chr3_-_58433313 0.13 ENSMUST00000029385.9
stress-associated endoplasmic reticulum protein 1
chr8_-_123159663 0.12 ENSMUST00000017604.10
cytochrome b-245, alpha polypeptide
chr15_-_4008913 0.12 ENSMUST00000022791.9
F-box protein 4
chr1_+_74324089 0.12 ENSMUST00000113805.8
ENSMUST00000027370.13
ENSMUST00000087226.11
paroxysmal nonkinesiogenic dyskinesia
chr6_+_129022843 0.12 ENSMUST00000032257.10
ENSMUST00000204320.2
killer cell lectin-like receptor subfamily B member 1F
chr19_+_53891730 0.12 ENSMUST00000025931.14
programmed cell death 4
chr4_-_43656437 0.12 ENSMUST00000030192.5
histidine triad nucleotide binding protein 2
chr6_-_40562700 0.12 ENSMUST00000177178.2
ENSMUST00000129948.9
ENSMUST00000101491.11
C-type lectin domain family 5, member a
chr1_+_52026296 0.12 ENSMUST00000168302.8
signal transducer and activator of transcription 4
chr11_-_72441054 0.12 ENSMUST00000021154.7
spinster homolog 3
chr7_+_44506561 0.12 ENSMUST00000107876.8
ENSMUST00000154968.2
ENSMUST00000003044.14
polynucleotide kinase 3'- phosphatase
chrX_+_10581248 0.12 ENSMUST00000144356.8
Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish))
chr9_+_73020708 0.12 ENSMUST00000169399.8
ENSMUST00000034738.14
ribosomal L24 domain containing 1
chr8_+_95720864 0.12 ENSMUST00000212141.2
adhesion G protein-coupled receptor G1
chr17_+_47816042 0.12 ENSMUST00000183044.8
ENSMUST00000037333.17
cyclin D3
chr17_+_43978280 0.12 ENSMUST00000170988.2
cytochrome P450, family 39, subfamily a, polypeptide 1
chr3_-_106126794 0.12 ENSMUST00000082219.6
chitinase-like 4
chr16_-_56537808 0.12 ENSMUST00000065515.14
Trk-fused gene
chr1_+_178626003 0.12 ENSMUST00000160789.2
kinesin family member 26B
chr14_+_26722319 0.12 ENSMUST00000035433.10
homeobox gene expressed in ES cells
chr9_-_108911438 0.12 ENSMUST00000192801.2
translational machinery associated 7
chr16_+_93404719 0.12 ENSMUST00000039659.9
ENSMUST00000231762.2
carbonyl reductase 1
chr9_+_21746785 0.12 ENSMUST00000058777.8
angiopoietin-like 8
chr14_-_31503869 0.12 ENSMUST00000227089.2
ankyrin repeat domain 28
chr17_-_48474356 0.12 ENSMUST00000027764.10
ENSMUST00000053612.14
RIKEN cDNA A530064D06 gene
chr17_-_71297885 0.12 ENSMUST00000038446.10
myosin, light chain 12B, regulatory
chr5_-_142891565 0.12 ENSMUST00000171419.8
actin, beta
chr2_+_90927053 0.12 ENSMUST00000132741.3
spleen focus forming virus (SFFV) proviral integration oncogene
chr3_-_53771185 0.12 ENSMUST00000122330.2
ENSMUST00000146598.8
ubiquitin-fold modifier 1
chr1_+_152683568 0.12 ENSMUST00000190323.7
neutrophil cytosolic factor 2
chr5_-_23821523 0.12 ENSMUST00000088392.9
serine/arginine-rich protein specific kinase 2
chr2_-_26823793 0.12 ENSMUST00000154651.2
ENSMUST00000015011.10
surfeit gene 4
chr4_-_133695204 0.12 ENSMUST00000100472.10
ENSMUST00000136327.2
high mobility group nucleosomal binding domain 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Spi1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0002215 defense response to nematode(GO:0002215)
0.2 0.7 GO:0045575 basophil activation(GO:0045575)
0.1 0.6 GO:0070103 regulation of interleukin-6-mediated signaling pathway(GO:0070103)
0.1 0.5 GO:1904207 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.1 0.4 GO:0034036 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.1 0.3 GO:0030573 bile acid catabolic process(GO:0030573)
0.1 0.3 GO:0060936 cardiac fibroblast cell differentiation(GO:0060935) cardiac fibroblast cell development(GO:0060936) epicardium-derived cardiac fibroblast cell differentiation(GO:0060938) epicardium-derived cardiac fibroblast cell development(GO:0060939) negative regulation of myofibroblast differentiation(GO:1904761) negative regulation of vascular smooth muscle cell differentiation(GO:1905064)
0.1 0.3 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.1 0.4 GO:0072223 metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262)
0.1 0.2 GO:0014805 smooth muscle adaptation(GO:0014805)
0.1 0.2 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.1 0.2 GO:0034769 basement membrane disassembly(GO:0034769)
0.1 0.3 GO:0071727 response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.1 0.2 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.1 0.2 GO:0098501 polynucleotide dephosphorylation(GO:0098501)
0.1 0.7 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
0.1 0.2 GO:0002543 activation of blood coagulation via clotting cascade(GO:0002543) phosphatidylserine exposure on blood platelet(GO:0097045)
0.1 0.3 GO:0043321 regulation of natural killer cell degranulation(GO:0043321)
0.1 0.2 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.1 0.2 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.1 0.2 GO:0002884 negative regulation of hypersensitivity(GO:0002884)
0.1 0.2 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.1 0.3 GO:0070425 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433)
0.1 0.3 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1 0.2 GO:0006711 estrogen catabolic process(GO:0006711)
0.1 0.3 GO:1904171 negative regulation of bleb assembly(GO:1904171)
0.1 0.2 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.1 0.2 GO:0033082 regulation of extrathymic T cell differentiation(GO:0033082)
0.1 0.3 GO:0038001 paracrine signaling(GO:0038001)
0.0 0.1 GO:0090135 actin filament branching(GO:0090135)
0.0 0.1 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.0 0.3 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.1 GO:0002434 immune complex clearance(GO:0002434)
0.0 0.2 GO:0038163 endomitotic cell cycle(GO:0007113) thrombopoietin-mediated signaling pathway(GO:0038163)
0.0 0.1 GO:1902022 L-lysine transport(GO:1902022)
0.0 0.2 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.0 0.1 GO:0071288 cellular response to mercury ion(GO:0071288)
0.0 0.1 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.0 0.1 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.1 GO:2000536 negative regulation of entry of bacterium into host cell(GO:2000536)
0.0 0.3 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.1 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
0.0 0.1 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.0 0.3 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.2 GO:0017126 nucleologenesis(GO:0017126)
0.0 0.2 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.4 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.0 0.0 GO:0072573 tolerance induction to lipopolysaccharide(GO:0072573)
0.0 0.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.2 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.3 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.0 0.1 GO:0046166 alditol catabolic process(GO:0019405) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.1 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.0 0.2 GO:0050917 sensory perception of umami taste(GO:0050917)
0.0 0.1 GO:0014739 positive regulation of muscle hyperplasia(GO:0014739)
0.0 0.1 GO:0060709 glycogen cell differentiation involved in embryonic placenta development(GO:0060709)
0.0 0.2 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 0.1 GO:0071449 response to lipid hydroperoxide(GO:0006982) cellular response to lipid hydroperoxide(GO:0071449)
0.0 0.1 GO:0051714 regulation of cytolysis in other organism(GO:0051710) positive regulation of cytolysis in other organism(GO:0051714)
0.0 0.2 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.2 GO:0006742 NADP catabolic process(GO:0006742)
0.0 0.1 GO:0080120 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.0 0.1 GO:0043181 vacuolar sequestering(GO:0043181)
0.0 0.3 GO:1903519 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0 0.1 GO:0002352 B cell negative selection(GO:0002352)
0.0 0.2 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.0 0.1 GO:1902226 regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240) zymogen granule exocytosis(GO:0070625)
0.0 0.1 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.0 0.1 GO:0072355 histone H3-T3 phosphorylation(GO:0072355)
0.0 0.7 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 0.1 GO:0019389 glucuronoside metabolic process(GO:0019389)
0.0 0.1 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.0 0.3 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.0 GO:2000349 negative regulation of CD40 signaling pathway(GO:2000349)
0.0 0.1 GO:0046100 hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.0 0.2 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.0 0.2 GO:0009227 nucleotide-sugar catabolic process(GO:0009227)
0.0 0.3 GO:0023021 termination of signal transduction(GO:0023021)
0.0 0.1 GO:0035633 maintenance of blood-brain barrier(GO:0035633)
0.0 0.2 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.1 GO:2000449 regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000449)
0.0 0.1 GO:0001805 type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805)
0.0 0.2 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.2 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.1 GO:0006168 adenine salvage(GO:0006168) adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0 0.2 GO:0032423 regulation of mismatch repair(GO:0032423) regulation of chondrocyte development(GO:0061181) negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0 0.1 GO:0090472 dibasic protein processing(GO:0090472)
0.0 0.2 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.2 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.1 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0 0.4 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.1 GO:0061622 glycolytic process through glucose-1-phosphate(GO:0061622)
0.0 0.3 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 0.1 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.0 0.2 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.1 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.0 0.2 GO:0031394 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0 0.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.1 GO:0045212 neurotransmitter receptor biosynthetic process(GO:0045212)
0.0 0.1 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.0 0.0 GO:0072249 metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.0 0.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.1 GO:0002309 T cell proliferation involved in immune response(GO:0002309)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.2 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.0 0.2 GO:0042117 monocyte activation(GO:0042117)
0.0 0.1 GO:1904579 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.0 0.4 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.1 GO:0031591 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.0 0.1 GO:0010286 heat acclimation(GO:0010286)
0.0 0.1 GO:1990428 miRNA transport(GO:1990428)
0.0 0.3 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.1 GO:2000434 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0 0.3 GO:1902947 regulation of tau-protein kinase activity(GO:1902947)
0.0 0.1 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.0 0.0 GO:0036446 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.0 0.3 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.1 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 0.1 GO:0010615 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.0 0.2 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.1 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.1 GO:2000395 regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.0 0.2 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0 0.1 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.0 0.5 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.1 GO:0032079 positive regulation of endodeoxyribonuclease activity(GO:0032079)
0.0 0.1 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.2 GO:0061713 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713) cellular response to folic acid(GO:0071231)
0.0 0.0 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.0 0.2 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.0 0.1 GO:1903416 response to glycoside(GO:1903416)
0.0 0.0 GO:0010481 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.0 0.2 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.1 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.0 0.3 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.1 GO:2000277 positive regulation of oxidative phosphorylation uncoupler activity(GO:2000277)
0.0 0.3 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.0 0.1 GO:0050689 negative regulation of defense response to virus by host(GO:0050689)
0.0 0.0 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.1 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.0 0.1 GO:1902953 positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
0.0 0.1 GO:0002584 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) negative regulation of antigen processing and presentation of peptide antigen(GO:0002584)
0.0 0.1 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.0 0.1 GO:0006183 GTP biosynthetic process(GO:0006183)
0.0 0.2 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.0 0.1 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.1 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.0 0.2 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.0 0.1 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.0 0.1 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.0 GO:2000328 positive regulation of memory T cell differentiation(GO:0043382) regulation of T-helper 17 cell lineage commitment(GO:2000328)
0.0 0.1 GO:0046203 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612) spermidine catabolic process(GO:0046203)
0.0 0.1 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.1 GO:0060994 regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994)
0.0 0.1 GO:0021570 rhombomere 4 development(GO:0021570)
0.0 0.2 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.0 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.0 0.1 GO:0070163 adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163)
0.0 0.1 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.1 GO:0035638 patched ligand maturation(GO:0007225) signal maturation(GO:0035638)
0.0 0.3 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.1 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 0.1 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.1 GO:1904959 regulation of cytochrome-c oxidase activity(GO:1904959)
0.0 0.1 GO:0040030 regulation of molecular function, epigenetic(GO:0040030)
0.0 0.1 GO:0042373 vitamin K metabolic process(GO:0042373)
0.0 0.1 GO:0036090 cleavage furrow ingression(GO:0036090)
0.0 0.1 GO:0002349 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.0 0.1 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.1 GO:0006116 NADH oxidation(GO:0006116)
0.0 0.1 GO:0002035 brain renin-angiotensin system(GO:0002035)
0.0 0.1 GO:0097325 melanocyte proliferation(GO:0097325)
0.0 0.0 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.0 0.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.0 0.1 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.1 GO:0042891 antibiotic transport(GO:0042891)
0.0 0.1 GO:0021682 nerve maturation(GO:0021682)
0.0 0.1 GO:1901355 response to rapamycin(GO:1901355)
0.0 0.7 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.2 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0 0.5 GO:0031424 keratinization(GO:0031424)
0.0 0.1 GO:2000656 regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657)
0.0 0.1 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.0 0.1 GO:1904453 positive regulation of GTP binding(GO:1904426) regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904451) positive regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904453)
0.0 0.0 GO:0061739 protein lipidation involved in autophagosome assembly(GO:0061739)
0.0 0.2 GO:1902590 viral budding(GO:0046755) multi-organism organelle organization(GO:1902590) multi-organism membrane budding(GO:1902592)
0.0 0.2 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.4 GO:0097066 response to thyroid hormone(GO:0097066)
0.0 0.1 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.0 0.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:1901896 positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.0 0.0 GO:0003274 endocardial cushion fusion(GO:0003274)
0.0 0.3 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.0 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
0.0 0.1 GO:1905154 negative regulation of membrane invagination(GO:1905154)
0.0 0.0 GO:0046021 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.0 0.1 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.2 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.1 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 0.1 GO:0051715 cytolysis in other organism(GO:0051715)
0.0 0.0 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.0 GO:0006624 vacuolar protein processing(GO:0006624)
0.0 0.2 GO:1904869 protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.0 0.1 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.1 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.0 0.1 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.0 GO:0006154 adenosine catabolic process(GO:0006154)
0.0 0.2 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.0 0.0 GO:0006597 spermine biosynthetic process(GO:0006597)
0.0 0.1 GO:0042631 cellular response to water deprivation(GO:0042631)
0.0 0.5 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.1 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.0 0.1 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.2 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.0 GO:0042128 nitrate assimilation(GO:0042128)
0.0 0.2 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.0 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.4 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.1 GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.0 0.0 GO:1901642 purine nucleoside transmembrane transport(GO:0015860) nucleoside transmembrane transport(GO:1901642)
0.0 0.1 GO:1902340 telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
0.0 0.1 GO:0021678 third ventricle development(GO:0021678)
0.0 0.1 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.1 GO:0045900 negative regulation of translational elongation(GO:0045900)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0019853 L-ascorbic acid biosynthetic process(GO:0019853)
0.0 0.2 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.1 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0 0.1 GO:0009223 pyrimidine nucleotide catabolic process(GO:0006244) pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.0 0.1 GO:1900060 negative regulation of ceramide biosynthetic process(GO:1900060)
0.0 0.3 GO:0045116 protein neddylation(GO:0045116)
0.0 0.2 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.1 GO:0021564 vagus nerve development(GO:0021564)
0.0 0.1 GO:0015961 diadenosine polyphosphate catabolic process(GO:0015961)
0.0 0.0 GO:0051542 elastin biosynthetic process(GO:0051542)
0.0 0.1 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.0 0.0 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.0 0.0 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.1 GO:0015867 ATP transport(GO:0015867)
0.0 0.1 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.0 GO:0001966 thigmotaxis(GO:0001966)
0.0 0.1 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.3 GO:0090662 ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0 0.0 GO:0015786 UDP-glucose transport(GO:0015786)
0.0 0.3 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.0 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 0.0 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0 0.0 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.0 GO:0036258 multivesicular body assembly(GO:0036258)
0.0 0.1 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.1 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.1 GO:0007549 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.1 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.1 GO:0070944 neutrophil mediated killing of bacterium(GO:0070944)
0.0 0.1 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.0 0.7 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 0.0 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.1 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.2 GO:0032225 regulation of synaptic transmission, dopaminergic(GO:0032225)
0.0 0.1 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.0 0.1 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.1 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 0.1 GO:0048242 epinephrine secretion(GO:0048242)
0.0 0.1 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.0 GO:0036275 response to 5-fluorouracil(GO:0036275)
0.0 0.1 GO:0010157 response to chlorate(GO:0010157)
0.0 0.1 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 0.1 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.0 0.0 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.0 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0 0.1 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.0 0.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.1 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.0 0.0 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279) positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.0 0.1 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.4 GO:0000731 DNA synthesis involved in DNA repair(GO:0000731)
0.0 0.0 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.0 GO:1904826 regulation of hydrogen sulfide biosynthetic process(GO:1904826) positive regulation of hydrogen sulfide biosynthetic process(GO:1904828)
0.0 0.1 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.0 GO:0033602 negative regulation of dopamine secretion(GO:0033602)
0.0 0.1 GO:0003062 regulation of heart rate by chemical signal(GO:0003062)
0.0 0.0 GO:0006014 D-ribose metabolic process(GO:0006014)
0.0 0.0 GO:0060151 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.0 0.0 GO:0072193 ureter smooth muscle development(GO:0072191) ureter smooth muscle cell differentiation(GO:0072193) kidney smooth muscle tissue development(GO:0072194)
0.0 0.1 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.0 GO:0009224 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) UMP salvage(GO:0044206) CMP metabolic process(GO:0046035)
0.0 0.1 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.1 GO:2000317 negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.0 0.1 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.1 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.0 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.1 GO:0033668 negative regulation by symbiont of host apoptotic process(GO:0033668) negative regulation by symbiont of host programmed cell death(GO:0052041) negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052490)
0.0 0.2 GO:0006544 glycine metabolic process(GO:0006544)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.8 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.5 GO:0097451 glial limiting end-foot(GO:0097451)
0.0 0.1 GO:0034457 Mpp10 complex(GO:0034457)
0.0 0.1 GO:0042643 actomyosin, actin portion(GO:0042643)
0.0 0.1 GO:0000814 ESCRT II complex(GO:0000814)
0.0 0.4 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.2 GO:0036284 tubulobulbar complex(GO:0036284)
0.0 0.2 GO:1990298 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
0.0 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.2 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.1 GO:1902912 pyruvate kinase complex(GO:1902912)
0.0 0.2 GO:0071817 MMXD complex(GO:0071817)
0.0 0.1 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.0 0.3 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.2 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.0 0.1 GO:0034686 integrin alphav-beta3 complex(GO:0034683) integrin alphav-beta8 complex(GO:0034686)
0.0 0.1 GO:0097144 BAX complex(GO:0097144)
0.0 0.2 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.1 GO:1990031 pinceau fiber(GO:1990031)
0.0 0.2 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.5 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.3 GO:0097255 R2TP complex(GO:0097255)
0.0 0.3 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.5 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.1 GO:0032997 Fc receptor complex(GO:0032997) Fc-epsilon receptor I complex(GO:0032998)
0.0 0.3 GO:0016589 NURF complex(GO:0016589)
0.0 0.2 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.1 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.1 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.0 0.1 GO:0070992 translation initiation complex(GO:0070992)
0.0 0.4 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.1 GO:1902636 kinociliary basal body(GO:1902636)
0.0 0.1 GO:0048500 signal recognition particle(GO:0048500)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.2 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.1 GO:0034665 integrin alpha1-beta1 complex(GO:0034665)
0.0 0.3 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.1 GO:0030891 VCB complex(GO:0030891)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.1 GO:0032010 phagolysosome(GO:0032010)
0.0 0.3 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 0.0 GO:0055087 Ski complex(GO:0055087)
0.0 0.1 GO:1990794 lateral part of cell(GO:0097574) basolateral part of cell(GO:1990794) rod bipolar cell terminal bouton(GO:1990795)
0.0 0.0 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 0.6 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 1.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.1 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.1 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.0 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.2 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.5 GO:0001533 cornified envelope(GO:0001533)
0.0 0.1 GO:1990032 parallel fiber(GO:1990032)
0.0 0.0 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.1 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.5 GO:0008305 integrin complex(GO:0008305)
0.0 0.5 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.0 GO:0070435 Shc-EGFR complex(GO:0070435)
0.0 0.2 GO:0001739 sex chromatin(GO:0001739)
0.0 0.1 GO:0061574 ASAP complex(GO:0061574)
0.0 0.1 GO:0097422 tubular endosome(GO:0097422)
0.0 0.1 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.0 0.3 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0000125 PCAF complex(GO:0000125)
0.0 0.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.0 GO:0005608 laminin-3 complex(GO:0005608)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.3 GO:0046930 pore complex(GO:0046930)
0.0 0.1 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 0.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.1 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0 0.0 GO:0097132 cyclin D2-CDK6 complex(GO:0097132)
0.0 0.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.0 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0044214 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.0 GO:0030312 external encapsulating structure(GO:0030312)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 0.0 GO:0098842 postsynaptic early endosome(GO:0098842)
0.0 0.0 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.1 GO:0044754 autolysosome(GO:0044754)
0.0 0.1 GO:0000322 storage vacuole(GO:0000322)
0.0 0.1 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.3 GO:0042588 zymogen granule(GO:0042588)
0.0 0.1 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.3 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.7 GO:0005761 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 0.4 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.1 0.4 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.1 0.3 GO:0008396 oxysterol 7-alpha-hydroxylase activity(GO:0008396)
0.1 0.2 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1 0.2 GO:0098973 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.1 0.2 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.1 0.5 GO:0071723 lipopeptide binding(GO:0071723)
0.1 0.2 GO:0035717 chemokine (C-C motif) ligand 7 binding(GO:0035717)
0.1 0.5 GO:0016936 galactoside binding(GO:0016936)
0.1 0.2 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 0.3 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.3 GO:0070051 fibrinogen binding(GO:0070051)
0.1 0.5 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.3 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.2 GO:0046403 polynucleotide 3'-phosphatase activity(GO:0046403)
0.0 0.3 GO:0019770 IgG receptor activity(GO:0019770)
0.0 0.1 GO:0035175 histone kinase activity (H3-S10 specific)(GO:0035175)
0.0 0.2 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0 0.1 GO:0004686 elongation factor-2 kinase activity(GO:0004686)
0.0 0.6 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.2 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 0.4 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0003999 adenine binding(GO:0002055) adenine phosphoribosyltransferase activity(GO:0003999)
0.0 0.2 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.0 0.1 GO:0033797 selenate reductase activity(GO:0033797)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.3 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.2 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.0 0.4 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.2 GO:0045340 mercury ion binding(GO:0045340)
0.0 0.1 GO:0001147 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.0 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.1 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.2 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.1 GO:0047804 cysteine-S-conjugate beta-lyase activity(GO:0047804)
0.0 0.4 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.2 GO:0043199 sulfate binding(GO:0043199)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.2 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.2 GO:0008312 7S RNA binding(GO:0008312)
0.0 0.2 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.2 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.1 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0 0.7 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.1 GO:0097100 supercoiled DNA binding(GO:0097100)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.1 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.0 0.2 GO:0010385 double-stranded methylated DNA binding(GO:0010385) hemi-methylated DNA-binding(GO:0044729)
0.0 0.1 GO:0051435 BH4 domain binding(GO:0051435)
0.0 0.1 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.1 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.0 0.2 GO:0004568 chitinase activity(GO:0004568)
0.0 0.9 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.3 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.3 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.1 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.0 0.1 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.0 0.1 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.1 GO:0030519 snoRNP binding(GO:0030519)
0.0 0.1 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.1 GO:0018169 ribosomal S6-glutamic acid ligase activity(GO:0018169)
0.0 0.2 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.1 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019)
0.0 0.1 GO:0019864 IgG binding(GO:0019864)
0.0 0.1 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 0.2 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.1 GO:0008775 acetate CoA-transferase activity(GO:0008775)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.1 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.0 0.1 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
0.0 0.1 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.0 0.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.1 GO:0004816 asparagine-tRNA ligase activity(GO:0004816)
0.0 0.1 GO:0035276 ethanol binding(GO:0035276)
0.0 0.3 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.1 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.1 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.2 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.2 GO:0051870 methotrexate binding(GO:0051870)
0.0 0.1 GO:0023029 MHC class Ib protein binding(GO:0023029)
0.0 0.1 GO:0042895 antibiotic transporter activity(GO:0042895)
0.0 0.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.3 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.1 GO:0004673 protein histidine kinase activity(GO:0004673)
0.0 0.2 GO:0050897 cobalt ion binding(GO:0050897)
0.0 0.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.1 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.0 0.1 GO:0019970 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.0 0.0 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.0 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.0 0.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.1 GO:1990715 mRNA CDS binding(GO:1990715)
0.0 0.0 GO:0035851 Krueppel-associated box domain binding(GO:0035851)
0.0 0.3 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.1 GO:0032407 MutSalpha complex binding(GO:0032407)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.0 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.0 0.4 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.1 GO:0002046 opsin binding(GO:0002046)
0.0 0.1 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.0 0.2 GO:0031386 protein tag(GO:0031386)
0.0 0.3 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.1 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.0 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.0 0.1 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.1 GO:0047710 bis(5'-adenosyl)-triphosphatase activity(GO:0047710)
0.0 0.3 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.1 GO:0016531 copper chaperone activity(GO:0016531)
0.0 2.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.0 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.0 0.1 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0 0.1 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.3 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.3 GO:0070628 proteasome binding(GO:0070628)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.0 0.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.1 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.4 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.5 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.0 GO:0036461 AP-3 adaptor complex binding(GO:0035651) BLOC-2 complex binding(GO:0036461)
0.0 0.0 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.0 GO:0045159 myosin II binding(GO:0045159)
0.0 0.3 GO:0051400 BH domain binding(GO:0051400)
0.0 0.4 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.0 GO:0051538 iron-responsive element binding(GO:0030350) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.0 0.1 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0 0.1 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.0 GO:0042282 hydroxymethylglutaryl-CoA reductase (NADPH) activity(GO:0004420) hydroxymethylglutaryl-CoA reductase activity(GO:0042282)
0.0 0.0 GO:0042806 fucose binding(GO:0042806)
0.0 0.0 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.0 0.8 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.1 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.0 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.2 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.0 0.0 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.0 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.2 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.0 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.1 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.1 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.0 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.0 0.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0034452 dynactin binding(GO:0034452)
0.0 0.0 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.0 0.1 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.1 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.4 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.0 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 0.1 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.1 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 0.1 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.0 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.2 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.5 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 1.2 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.3 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.4 PID MYC PATHWAY C-MYC pathway
0.0 1.2 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.1 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.2 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.2 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.4 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.2 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.1 0.2 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 0.1 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.0 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 0.2 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.4 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.7 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.4 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.4 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.3 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.5 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.7 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.3 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0 0.1 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 2.3 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 1.3 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 0.3 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.3 REACTOME SIGNALING BY NOTCH3 Genes involved in Signaling by NOTCH3
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.3 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.6 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.1 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.5 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.4 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.3 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.2 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.2 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.4 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.1 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.1 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.