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avrg: GFI1 WT vs 36n/n vs KD

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Results for Spic

Z-value: 0.46

Motif logo

Transcription factors associated with Spic

Gene Symbol Gene ID Gene Info
ENSMUSG00000004359.17 Spi-C transcription factor (Spi-1/PU.1 related)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Spicmm39_v1_chr10_-_88518878_88518892-0.513.8e-01Click!

Activity profile of Spic motif

Sorted Z-values of Spic motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_80145805 0.54 ENSMUST00000028392.8
DnaJ heat shock protein family (Hsp40) member C10
chr9_+_20556147 0.29 ENSMUST00000161882.8
ubiquitin-like 5
chr4_+_129229805 0.28 ENSMUST00000119480.2
zinc finger and BTB domain containing 8 opposite strand
chr11_+_87684548 0.28 ENSMUST00000143021.9
myeloperoxidase
chr8_+_95650315 0.27 ENSMUST00000153448.9
ENSMUST00000166802.9
ENSMUST00000074570.10
adhesion G protein-coupled receptor G5
chr19_-_41884599 0.26 ENSMUST00000038677.5
ribosomal RNA processing 12 homolog
chr11_+_87684299 0.26 ENSMUST00000020779.11
myeloperoxidase
chr7_-_126303887 0.25 ENSMUST00000131415.8
coronin, actin binding protein 1A
chr19_+_4282040 0.23 ENSMUST00000237518.2
polymerase (DNA-directed), delta 4
chr6_-_56681657 0.22 ENSMUST00000176595.3
ENSMUST00000170382.5
ENSMUST00000203958.2
LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated
chr3_-_94794256 0.22 ENSMUST00000005923.7
proteasome (prosome, macropain) subunit, beta type 4
chr7_-_126303689 0.20 ENSMUST00000135087.8
coronin, actin binding protein 1A
chr5_-_138169253 0.19 ENSMUST00000139983.8
minichromosome maintenance complex component 7
chr5_-_138169509 0.19 ENSMUST00000153867.8
minichromosome maintenance complex component 7
chr4_-_136620376 0.19 ENSMUST00000046332.6
complement component 1, q subcomponent, C chain
chr17_+_75024727 0.18 ENSMUST00000024882.8
ENSMUST00000234751.2
ENSMUST00000234568.2
tetratricopeptide repeat domain 27
chr17_+_13135313 0.18 ENSMUST00000143961.2
ENSMUST00000233286.2
t-complex protein 1
chr3_-_65299967 0.18 ENSMUST00000119896.2
signal sequence receptor, gamma
chr10_-_17898838 0.17 ENSMUST00000220433.2
ABRA C-terminal like
chr4_-_117749191 0.17 ENSMUST00000030265.4
DPH2 homolog
chr12_+_70499869 0.16 ENSMUST00000021471.13
thioredoxin-related transmembrane protein 1
chr8_+_107783502 0.16 ENSMUST00000034392.13
ENSMUST00000170962.3
NIP7, nucleolar pre-rRNA processing protein
chr19_+_11747721 0.16 ENSMUST00000167199.3
mitochondrial ribosomal protein L16
chr10_-_116899239 0.16 ENSMUST00000219036.2
ENSMUST00000218059.2
chaperonin containing Tcp1, subunit 2 (beta)
chr13_-_58276353 0.16 ENSMUST00000007980.7
heterogeneous nuclear ribonucleoprotein A0
chr4_-_136626073 0.16 ENSMUST00000046285.6
complement component 1, q subcomponent, alpha polypeptide
chr2_+_43638814 0.15 ENSMUST00000112824.8
ENSMUST00000055776.8
Rho GTPase activating protein 15
chr6_-_136918844 0.15 ENSMUST00000204934.2
Rho, GDP dissociation inhibitor (GDI) beta
chrX_-_168103266 0.15 ENSMUST00000033717.9
ENSMUST00000112115.2
holocytochrome c synthetase
chr5_+_149202157 0.15 ENSMUST00000200806.4
arachidonate 5-lipoxygenase activating protein
chr7_-_44888465 0.15 ENSMUST00000210078.2
CD37 antigen
chr10_+_79715448 0.15 ENSMUST00000006679.15
proteinase 3
chr10_-_17898977 0.15 ENSMUST00000020002.9
ABRA C-terminal like
chr1_+_152683568 0.15 ENSMUST00000190323.7
neutrophil cytosolic factor 2
chr14_+_8507874 0.15 ENSMUST00000225325.2
THO complex 7
chrX_+_7750558 0.15 ENSMUST00000208640.2
ENSMUST00000207114.2
ENSMUST00000208633.2
ENSMUST00000208397.2
ENSMUST00000153620.3
ENSMUST00000123277.8
solute carrier family 35 (UDP-galactose transporter), member A2
chr10_-_116899664 0.15 ENSMUST00000218719.2
ENSMUST00000219573.2
ENSMUST00000047672.9
chaperonin containing Tcp1, subunit 2 (beta)
chr12_+_100076407 0.15 ENSMUST00000021595.10
protease (prosome, macropain) 26S subunit, ATPase 1
chr10_-_17898938 0.14 ENSMUST00000220110.2
ABRA C-terminal like
chrX_-_50106844 0.14 ENSMUST00000053593.8
RAP2C, member of RAS oncogene family
chr17_-_35391583 0.14 ENSMUST00000173106.2
allograft inflammatory factor 1
chr2_+_163836880 0.14 ENSMUST00000018470.10
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
chr12_+_75355082 0.14 ENSMUST00000118602.8
ENSMUST00000118966.8
ENSMUST00000055390.6
ras homolog family member J
chr7_-_19005721 0.13 ENSMUST00000032561.9
vasodilator-stimulated phosphoprotein
chr4_-_136613498 0.13 ENSMUST00000046384.9
complement component 1, q subcomponent, beta polypeptide
chr11_-_69553390 0.13 ENSMUST00000129224.8
ENSMUST00000155200.8
mannose-P-dolichol utilization defect 1
chr1_-_149836974 0.13 ENSMUST00000190507.2
ENSMUST00000070200.15
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chrX_-_133442596 0.13 ENSMUST00000054213.5
translocase of inner mitochondrial membrane 8A1
chr11_+_78215026 0.13 ENSMUST00000102478.4
aldolase C, fructose-bisphosphate
chr11_-_119190830 0.13 ENSMUST00000106253.2
eukaryotic translation initiation factor 4A3
chr3_-_108053396 0.13 ENSMUST00000000001.5
guanine nucleotide binding protein (G protein), alpha inhibiting 3
chr11_+_58221538 0.13 ENSMUST00000116376.9
SH3 binding domain protein 5 like
chr5_-_140368482 0.13 ENSMUST00000196566.5
sorting nexin 8
chr9_+_107440484 0.13 ENSMUST00000193418.2
tumor suppressor 2, mitochondrial calcium regulator
chr11_-_113456568 0.13 ENSMUST00000071539.10
ENSMUST00000106633.10
ENSMUST00000042657.16
ENSMUST00000149034.8
solute carrier family 39 (metal ion transporter), member 11
chr13_-_96807346 0.12 ENSMUST00000022176.15
3-hydroxy-3-methylglutaryl-Coenzyme A reductase
chr9_-_114610879 0.12 ENSMUST00000084867.9
ENSMUST00000216760.2
ENSMUST00000035009.16
CKLF-like MARVEL transmembrane domain containing 7
chr9_-_105398346 0.12 ENSMUST00000176770.8
ENSMUST00000085133.13
ATPase, Ca++-sequestering
chr12_+_84408742 0.12 ENSMUST00000021661.13
coenzyme Q6 monooxygenase
chr8_-_85807281 0.11 ENSMUST00000152785.8
WD repeat domain containing 83
chr6_-_124710030 0.11 ENSMUST00000173647.2
protein tyrosine phosphatase, non-receptor type 6
chr3_-_65300000 0.11 ENSMUST00000029414.12
signal sequence receptor, gamma
chr19_+_6135013 0.11 ENSMUST00000025704.3
cell division cycle associated 5
chr4_+_140428777 0.11 ENSMUST00000138808.8
ENSMUST00000038893.6
regulator of chromosome condensation 2
chr11_+_70021155 0.11 ENSMUST00000041550.12
ENSMUST00000165951.8
macrophage galactose N-acetyl-galactosamine specific lectin 2
chrX_-_135642025 0.11 ENSMUST00000155207.8
ENSMUST00000080411.13
ENSMUST00000169418.8
mortality factor 4 like 2
chr9_+_7184514 0.11 ENSMUST00000215683.2
ENSMUST00000034499.10
DCN1, defective in cullin neddylation 1, domain containing 5 (S. cerevisiae)
chr9_+_46184362 0.11 ENSMUST00000156440.8
ENSMUST00000114552.4
ZPR1 zinc finger
chr12_+_55445560 0.11 ENSMUST00000021412.9
proteasome subunit alpha 6
chr1_-_170804116 0.10 ENSMUST00000159969.8
Fc receptor, IgG, low affinity IIb
chr19_-_6886965 0.10 ENSMUST00000173091.2
peroxiredoxin 5
chr8_+_93581946 0.10 ENSMUST00000046290.3
ENSMUST00000210099.2
lysophosphatidylcholine acyltransferase 2
chr15_+_76253084 0.10 ENSMUST00000023213.8
HGH1 homolog
chr11_+_58221569 0.10 ENSMUST00000073128.7
SH3 binding domain protein 5 like
chrX_+_7750483 0.10 ENSMUST00000115663.10
ENSMUST00000096514.11
solute carrier family 35 (UDP-galactose transporter), member A2
chr14_-_56026266 0.10 ENSMUST00000168716.8
ENSMUST00000178399.3
ENSMUST00000022830.14
receptor-interacting serine-threonine kinase 3
chr9_+_56858162 0.10 ENSMUST00000068856.5
snurportin 1
chr17_-_6923299 0.10 ENSMUST00000179554.3
dynein light chain Tctex-type 1F
chr17_+_13135216 0.10 ENSMUST00000089024.13
ENSMUST00000151287.8
t-complex protein 1
chr11_-_69873343 0.10 ENSMUST00000147437.3
elongator acetyltransferase complex subunit 5
chr8_-_70169500 0.10 ENSMUST00000238408.2
ENSMUST00000238418.2
ENSMUST00000238753.2
zinc finger protein 869
chr16_-_75563645 0.10 ENSMUST00000114244.2
ENSMUST00000046283.16
heat shock protein 70 family, member 13
chr8_+_22682816 0.10 ENSMUST00000033866.9
vacuolar protein sorting 36
chr8_-_85807308 0.10 ENSMUST00000093357.12
WD repeat domain containing 83
chr3_-_106697459 0.10 ENSMUST00000038845.10
CD53 antigen
chr8_+_85798348 0.10 ENSMUST00000078665.13
deoxyhypusine synthase
chr6_+_129326927 0.10 ENSMUST00000065289.6
C-type lectin domain family 12, member a
chr9_+_109704609 0.09 ENSMUST00000094324.8
cell division cycle 25A
chr5_-_110928436 0.09 ENSMUST00000149208.2
ENSMUST00000031483.15
ENSMUST00000086643.12
ENSMUST00000170468.8
ENSMUST00000031481.13
pseudouridine synthase 1
chr16_+_32238520 0.09 ENSMUST00000014220.15
ENSMUST00000080316.8
dynein light chain Tctex-type 2B
chr5_-_110987441 0.09 ENSMUST00000145318.2
HscB iron-sulfur cluster co-chaperone
chrX_+_7750261 0.09 ENSMUST00000115660.12
solute carrier family 35 (UDP-galactose transporter), member A2
chr11_-_119190896 0.09 ENSMUST00000026667.15
eukaryotic translation initiation factor 4A3
chr19_+_6111204 0.09 ENSMUST00000162726.5
zinc finger, HIT domain containing 2
chr6_+_113581708 0.09 ENSMUST00000035725.7
BRICK1, SCAR/WAVE actin-nucleating complex subunit
chr6_+_134391385 0.09 ENSMUST00000111960.2
BCL2-like 14 (apoptosis facilitator)
chr17_-_24292453 0.09 ENSMUST00000017090.6
potassium channel tetramerisation domain containing 5
chr13_+_90237824 0.09 ENSMUST00000012566.9
transmembrane protein 167
chr17_+_6869070 0.09 ENSMUST00000092966.5
dynein light chain Tctex-type 1C
chr6_-_48685108 0.09 ENSMUST00000126422.3
ENSMUST00000119315.2
ENSMUST00000053661.7
GTPase, IMAP family member 6
chr15_+_78314251 0.09 ENSMUST00000229622.2
ENSMUST00000162808.2
potassium channel tetramerisation domain containing 17
chr3_+_135191366 0.09 ENSMUST00000029814.10
mannosidase, beta A, lysosomal
chr4_-_41314877 0.09 ENSMUST00000030145.9
DDB1 and CUL4 associated factor 12
chr7_+_127368981 0.09 ENSMUST00000118865.8
ENSMUST00000061587.13
ENSMUST00000121504.2
ORAI calcium release-activated calcium modulator 3
chr4_-_117744476 0.08 ENSMUST00000132073.2
ENSMUST00000150204.8
ENSMUST00000147845.2
ENSMUST00000036380.14
ENSMUST00000136596.2
ATPase, H+ transporting, lysosomal V0 subunit B
chr11_-_102109748 0.08 ENSMUST00000131254.2
histone deacetylase 5
chr9_+_99457829 0.08 ENSMUST00000066650.12
ENSMUST00000148987.8
debranching RNA lariats 1
chr12_-_80690573 0.08 ENSMUST00000166931.2
ENSMUST00000218364.2
ERH mRNA splicing and mitosis factor
chr5_+_115465205 0.08 ENSMUST00000031513.14
serine and arginine-rich splicing factor 9
chr1_+_52158721 0.08 ENSMUST00000186057.7
signal transducer and activator of transcription 1
chr2_+_130266253 0.08 ENSMUST00000128994.8
ENSMUST00000028900.11
VSP16 CORVET/HOPS core subunit
chr15_-_63932176 0.08 ENSMUST00000226675.2
ENSMUST00000228226.2
ENSMUST00000227024.2
CYFIP related Rac1 interactor B
chr15_+_103362195 0.08 ENSMUST00000047405.9
NCK associated protein 1 like
chr13_-_39144475 0.08 ENSMUST00000225331.2
ENSMUST00000224645.2
ENSMUST00000167513.3
ENSMUST00000225568.2
solute carrier family 35, member B3
chr1_-_171122509 0.08 ENSMUST00000111302.4
ENSMUST00000080001.9
ubiquitin-fold modifier conjugating enzyme 1
chr5_+_149201577 0.08 ENSMUST00000071130.5
arachidonate 5-lipoxygenase activating protein
chr9_-_37568570 0.08 ENSMUST00000117654.3
transforming growth factor beta regulated gene 1
chr9_+_108911547 0.08 ENSMUST00000026735.9
coiled-coil domain containing 51
chr8_+_126456710 0.08 ENSMUST00000143504.8
nucleoside-triphosphatase, cancer-related
chr7_+_28533279 0.08 ENSMUST00000208971.2
ENSMUST00000066723.15
lectin, galactose binding, soluble 4
chr11_-_102771751 0.08 ENSMUST00000021306.14
elongation factor Tu GTP binding domain containing 2
chr5_+_86219593 0.08 ENSMUST00000198435.5
ENSMUST00000031171.9
signal transducing adaptor family member 1
chr7_+_28140352 0.08 ENSMUST00000078845.13
glia maturation factor, gamma
chr6_+_123206802 0.08 ENSMUST00000112554.9
ENSMUST00000024118.11
ENSMUST00000117130.8
C-type lectin domain family 4, member n
chr11_+_106146966 0.08 ENSMUST00000021049.9
protease (prosome, macropain) 26S subunit, ATPase 5
chr7_+_44506731 0.08 ENSMUST00000098478.7
polynucleotide kinase 3'- phosphatase
chr13_-_98399533 0.08 ENSMUST00000040972.4
UTP15 small subunit processome component
chr15_-_57755753 0.08 ENSMUST00000022993.7
Der1-like domain family, member 1
chr19_+_12438125 0.07 ENSMUST00000081035.9
macrophage expressed gene 1
chr11_+_88095222 0.07 ENSMUST00000118784.8
ENSMUST00000139170.8
ENSMUST00000107915.10
ENSMUST00000144070.3
mitochondrial ribosomal protein S23
chr7_+_105289655 0.07 ENSMUST00000058333.10
translocase of inner mitochondrial membrane 10B
chr7_+_44506561 0.07 ENSMUST00000107876.8
ENSMUST00000154968.2
ENSMUST00000003044.14
polynucleotide kinase 3'- phosphatase
chr18_+_67338437 0.07 ENSMUST00000210564.3
charged multivesicular body protein 1B
chr4_-_133601990 0.07 ENSMUST00000168974.9
ribosomal protein S6 kinase polypeptide 1
chr7_-_126074222 0.07 ENSMUST00000205497.2
SH2B adaptor protein 1
chr2_-_25101354 0.07 ENSMUST00000059849.15
negative elongation factor complex member B
chr11_-_106605772 0.07 ENSMUST00000124958.3
platelet/endothelial cell adhesion molecule 1
chr19_-_18609118 0.07 ENSMUST00000025631.7
ENSMUST00000236615.2
osteoclast stimulating factor 1
chr12_+_84408803 0.07 ENSMUST00000110278.8
ENSMUST00000145522.2
coenzyme Q6 monooxygenase
chr8_+_85428391 0.07 ENSMUST00000238338.2
lymphoblastomic leukemia 1
chr8_-_96161414 0.07 ENSMUST00000211908.2
cilia and flagella associated protein 20
chr1_+_52158599 0.07 ENSMUST00000186574.7
ENSMUST00000070968.14
ENSMUST00000191435.7
ENSMUST00000186857.7
ENSMUST00000188681.7
signal transducer and activator of transcription 1
chr5_+_35156389 0.07 ENSMUST00000114281.8
ENSMUST00000114280.8
regulator of G-protein signaling 12
chr4_+_130640611 0.07 ENSMUST00000156225.8
ENSMUST00000156742.8
lysosomal-associated protein transmembrane 5
chr11_+_98798627 0.07 ENSMUST00000092706.13
cell division cycle 6
chr7_-_126641565 0.07 ENSMUST00000205806.2
kinesin family member 22
chr9_-_44272923 0.07 ENSMUST00000034644.10
VPS11, CORVET/HOPS core subunit
chr1_+_75498162 0.07 ENSMUST00000027414.16
ENSMUST00000113553.2
serine/threonine kinase 11 interacting protein
chr5_+_124690908 0.07 ENSMUST00000071057.14
ENSMUST00000111438.2
DEAD box helicase 55
chr1_-_170803680 0.07 ENSMUST00000027966.14
ENSMUST00000081103.12
ENSMUST00000159688.2
Fc receptor, IgG, low affinity IIb
chr1_+_155034452 0.07 ENSMUST00000027743.13
ENSMUST00000195302.6
syntaxin 6
chr14_-_47514308 0.07 ENSMUST00000111792.9
WD repeat and HMG-box DNA binding protein 1
chrX_-_135641869 0.07 ENSMUST00000166930.8
ENSMUST00000113095.8
mortality factor 4 like 2
chr3_+_103875261 0.07 ENSMUST00000117150.8
putative homeodomain transcription factor 1
chr5_-_130031842 0.07 ENSMUST00000026613.14
glucuronidase, beta
chrX_+_106132840 0.07 ENSMUST00000118666.8
ENSMUST00000053375.4
purinergic receptor P2Y, G-protein coupled 10
chr4_-_86775602 0.07 ENSMUST00000102814.5
ribosomal protein S6
chr3_+_129326285 0.07 ENSMUST00000197235.5
ELOVL family member 6, elongation of long chain fatty acids (yeast)
chr5_+_67464284 0.07 ENSMUST00000113676.6
ENSMUST00000162372.8
solute carrier family 30 (zinc transporter), member 9
chr9_-_117979147 0.07 ENSMUST00000215799.2
ENSMUST00000044220.11
COX assembly mitochondrial protein 1
chr1_+_164135230 0.07 ENSMUST00000193683.6
NME/NM23 family member 7
chr12_-_79027531 0.07 ENSMUST00000174072.8
transmembrane protein 229B
chr11_-_79418500 0.07 ENSMUST00000154415.2
ecotropic viral integration site 2a
chr13_+_108180957 0.06 ENSMUST00000095458.6
ENSMUST00000223808.2
ENSMUST00000226042.2
ENSMUST00000225972.2
small integral membrane protein 15
chr11_-_53191208 0.06 ENSMUST00000020630.8
heat shock protein 4
chr11_+_88095206 0.06 ENSMUST00000024486.14
mitochondrial ribosomal protein S23
chr1_-_167112784 0.06 ENSMUST00000053686.9
uridine-cytidine kinase 2
chr4_+_118266582 0.06 ENSMUST00000144577.2
mediator complex subunit 8
chr15_+_25774070 0.06 ENSMUST00000125667.3
myosin X
chr9_+_89081407 0.06 ENSMUST00000138109.2
predicted gene 29094
chr4_-_116484675 0.06 ENSMUST00000081182.5
ENSMUST00000030457.12
nuclear autoantigenic sperm protein (histone-binding)
chr17_+_34149820 0.06 ENSMUST00000234226.2
ral guanine nucleotide dissociation stimulator-like 2
chr12_-_44256843 0.06 ENSMUST00000220421.2
DnaJ heat shock protein family (Hsp40) member B9
chrX_-_56371953 0.06 ENSMUST00000176986.8
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr6_-_124715542 0.06 ENSMUST00000174265.2
protein tyrosine phosphatase, non-receptor type 6
chr1_-_144124871 0.06 ENSMUST00000189061.7
regulator of G-protein signaling 1
chr13_-_14237958 0.06 ENSMUST00000223174.2
geranylgeranyl diphosphate synthase 1
chr19_-_45580258 0.06 ENSMUST00000160003.8
ENSMUST00000162879.8
F-box and WD-40 domain protein 4
chr17_+_57586094 0.06 ENSMUST00000169220.9
ENSMUST00000005889.16
ENSMUST00000112870.5
vav 1 oncogene
chr5_-_121665249 0.06 ENSMUST00000152270.8
MAP kinase-activated protein kinase 5
chr2_+_181138958 0.06 ENSMUST00000149163.8
ENSMUST00000000844.15
ENSMUST00000184849.8
ENSMUST00000108800.8
ENSMUST00000069712.9
tumor protein D52-like 2
chr14_+_103284413 0.06 ENSMUST00000022722.7
aconitate decarboxylase 1
chr1_-_58009191 0.06 ENSMUST00000159826.2
ENSMUST00000164963.8
potassium channel tetramerisation domain containing 18
chr3_-_53771185 0.06 ENSMUST00000122330.2
ENSMUST00000146598.8
ubiquitin-fold modifier 1
chr2_+_118943274 0.06 ENSMUST00000140939.8
ENSMUST00000028795.10
RAD51 recombinase
chr11_+_6510167 0.06 ENSMUST00000109722.9
cerebral cavernous malformation 2
chr12_+_28801802 0.06 ENSMUST00000221877.2
ENSMUST00000222407.2
ENSMUST00000221555.2
EARP complex and GARP complex interacting protein 1
chr10_-_89568106 0.06 ENSMUST00000020109.5
ARP6 actin-related protein 6
chr6_+_48661503 0.06 ENSMUST00000067506.14
ENSMUST00000119575.8
ENSMUST00000121957.8
ENSMUST00000090070.6
GTPase, IMAP family member 4
chr13_+_98399693 0.06 ENSMUST00000091356.11
ENSMUST00000123924.8
ankyrin repeat, family A (RFXANK-like), 2
chr19_-_6887361 0.06 ENSMUST00000025904.12
peroxiredoxin 5
chr5_+_31609802 0.06 ENSMUST00000202244.4
zinc finger protein 512
chr11_-_120348762 0.06 ENSMUST00000137632.2
ENSMUST00000044007.3
oxidoreductase like domain containing 1
chr10_-_44334711 0.06 ENSMUST00000039174.11
PR domain containing 1, with ZNF domain
chr2_-_149978560 0.06 ENSMUST00000094538.6
ENSMUST00000109931.8
ENSMUST00000089207.13
zinc finger protein 120
chr16_+_36755338 0.06 ENSMUST00000023531.15
hematopoietic cell specific Lyn substrate 1
chr15_-_98729333 0.06 ENSMUST00000168846.3
protein kinase, AMP-activated, gamma 1 non-catalytic subunit
chr15_+_38976260 0.06 ENSMUST00000022909.10
DDB1 and CUL4 associated factor 13
chr1_+_52158693 0.06 ENSMUST00000189347.7
signal transducer and activator of transcription 1
chrX_+_70408351 0.06 ENSMUST00000146213.8
ENSMUST00000114601.8
ENSMUST00000015358.8
myotubularin related protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Spic

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0002149 hypochlorous acid metabolic process(GO:0002148) hypochlorous acid biosynthetic process(GO:0002149)
0.1 0.5 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 0.6 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.1 0.2 GO:0034240 negative regulation of macrophage fusion(GO:0034240)
0.1 0.2 GO:0032618 interleukin-15 production(GO:0032618) response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572)
0.1 0.5 GO:0061502 uropod organization(GO:0032796) early endosome to recycling endosome transport(GO:0061502)
0.1 0.2 GO:1904569 regulation of selenocysteine incorporation(GO:1904569)
0.0 0.1 GO:0098501 polynucleotide dephosphorylation(GO:0098501)
0.0 0.1 GO:0014739 positive regulation of muscle hyperplasia(GO:0014739)
0.0 0.2 GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) negative regulation of hypersensitivity(GO:0002884) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.0 0.2 GO:0060785 regulation of apoptosis involved in tissue homeostasis(GO:0060785)
0.0 0.2 GO:0006742 NADP catabolic process(GO:0006742)
0.0 0.2 GO:0002540 leukotriene production involved in inflammatory response(GO:0002540)
0.0 0.3 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.0 0.1 GO:0090673 endothelial cell-matrix adhesion(GO:0090673)
0.0 0.1 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.0 0.2 GO:0070893 transposon integration(GO:0070893) regulation of transposon integration(GO:0070894) negative regulation of transposon integration(GO:0070895)
0.0 0.1 GO:0051030 snRNA transport(GO:0051030)
0.0 0.2 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.4 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.1 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612) spermidine catabolic process(GO:0046203)
0.0 0.1 GO:0030026 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.0 0.1 GO:0033082 regulation of extrathymic T cell differentiation(GO:0033082)
0.0 0.2 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.0 0.1 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.0 0.1 GO:0071846 actin filament debranching(GO:0071846)
0.0 0.1 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.1 GO:0032066 nucleolus to nucleoplasm transport(GO:0032066)
0.0 0.1 GO:2000449 regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000449)
0.0 0.1 GO:1903969 regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972)
0.0 0.1 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.2 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.0 0.1 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.1 GO:0031394 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0 0.1 GO:0071922 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.1 GO:0070829 heterochromatin maintenance(GO:0070829)
0.0 0.1 GO:0009224 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) UMP salvage(GO:0044206) CMP metabolic process(GO:0046035)
0.0 0.1 GO:0071931 Cajal body organization(GO:0030576) positive regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071931)
0.0 0.1 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.1 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.0 0.1 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.0 0.1 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.0 0.1 GO:0070358 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376) actin polymerization-dependent cell motility(GO:0070358)
0.0 0.2 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.1 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.0 0.1 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.1 GO:0046038 GMP catabolic process(GO:0046038)
0.0 0.1 GO:1903094 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.0 0.1 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.0 0.3 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.1 GO:0043321 regulation of natural killer cell degranulation(GO:0043321)
0.0 0.1 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.0 0.0 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.0 0.1 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.0 0.1 GO:0002309 T cell proliferation involved in immune response(GO:0002309)
0.0 0.1 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.0 0.0 GO:0060559 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.0 0.0 GO:0006393 termination of mitochondrial transcription(GO:0006393)
0.0 0.2 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.3 GO:0006743 ubiquinone metabolic process(GO:0006743)
0.0 0.0 GO:0007439 ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
0.0 0.0 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.1 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.0 0.1 GO:0097309 cap1 mRNA methylation(GO:0097309)
0.0 0.1 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.0 0.2 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.1 GO:0060296 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0 0.2 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.0 GO:1903722 regulation of centriole elongation(GO:1903722)
0.0 0.0 GO:0035973 aggrephagy(GO:0035973) protein lipidation involved in autophagosome assembly(GO:0061739)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.1 GO:0000814 ESCRT II complex(GO:0000814)
0.0 0.5 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.5 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 0.2 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.4 GO:0042555 MCM complex(GO:0042555)
0.0 0.3 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.2 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.1 GO:1990393 3M complex(GO:1990393)
0.0 0.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.1 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 0.6 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:1902560 GMP reductase complex(GO:1902560)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.3 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.0 GO:0043614 multi-eIF complex(GO:0043614)
0.0 0.0 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.1 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.3 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.1 GO:0033263 CORVET complex(GO:0033263)
0.0 0.0 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.1 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.1 GO:0097342 ripoptosome(GO:0097342)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.2 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
0.0 0.1 GO:0042282 hydroxymethylglutaryl-CoA reductase (NADPH) activity(GO:0004420) hydroxymethylglutaryl-CoA reductase activity(GO:0042282)
0.0 0.2 GO:0072541 peroxynitrite reductase activity(GO:0072541)
0.0 0.1 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.0 0.1 GO:0046403 polynucleotide 3'-phosphatase activity(GO:0046403)
0.0 0.1 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0 0.6 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.1 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.0 0.2 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.1 GO:0071796 K6-linked polyubiquitin binding(GO:0071796)
0.0 0.2 GO:0019770 IgG receptor activity(GO:0019770)
0.0 0.1 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.1 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.5 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.3 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.2 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.2 GO:0016936 galactoside binding(GO:0016936)
0.0 0.1 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0 0.2 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.0 GO:0030622 U4atac snRNA binding(GO:0030622)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.0 0.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.0 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.5 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.3 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.0 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 0.1 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.0 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.3 GO:0097602 cullin family protein binding(GO:0097602)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.7 PID ATR PATHWAY ATR signaling pathway
0.0 0.6 PID IL23 PATHWAY IL23-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.4 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.6 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.5 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.1 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0 0.6 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6