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avrg: GFI1 WT vs 36n/n vs KD

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Results for Stat1

Z-value: 1.83

Motif logo

Transcription factors associated with Stat1

Gene Symbol Gene ID Gene Info
ENSMUSG00000026104.15 signal transducer and activator of transcription 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Stat1mm39_v1_chr1_+_52158721_521587831.008.4e-05Click!

Activity profile of Stat1 motif

Sorted Z-values of Stat1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_142202642 1.92 ENSMUST00000090127.7
guanylate binding protein 5
chr7_+_43086432 1.69 ENSMUST00000070518.4
natural killer cell group 7 sequence
chr9_+_110867807 1.43 ENSMUST00000197575.2
lactotransferrin
chr17_+_29309942 1.28 ENSMUST00000119901.9
cyclin-dependent kinase inhibitor 1A (P21)
chr17_-_34406193 1.21 ENSMUST00000173831.3
proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)
chr17_-_56428968 1.17 ENSMUST00000041357.9
leucine-rich alpha-2-glycoprotein 1
chr7_+_43086554 1.16 ENSMUST00000206741.2
natural killer cell group 7 sequence
chr12_-_108859123 1.10 ENSMUST00000161154.2
ENSMUST00000161410.8
tryptophanyl-tRNA synthetase
chr10_-_17898938 1.01 ENSMUST00000220110.2
ABRA C-terminal like
chr1_+_134110142 0.95 ENSMUST00000082060.10
ENSMUST00000153856.8
ENSMUST00000133701.8
ENSMUST00000132873.8
chitinase-like 1
chr2_-_65955338 0.83 ENSMUST00000028378.4
polypeptide N-acetylgalactosaminyltransferase 3
chr2_-_163592127 0.79 ENSMUST00000017841.4
adenosine deaminase
chr12_-_112637998 0.77 ENSMUST00000128300.9
thymoma viral proto-oncogene 1
chr4_-_136613498 0.77 ENSMUST00000046384.9
complement component 1, q subcomponent, beta polypeptide
chr17_+_34406762 0.76 ENSMUST00000041633.15
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr19_-_46950355 0.73 ENSMUST00000236501.2
5'-nucleotidase, cytosolic II
chr17_+_34406523 0.71 ENSMUST00000170086.8
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr10_-_79911245 0.66 ENSMUST00000217972.2
strawberry notch 2
chr11_+_53660834 0.63 ENSMUST00000108920.10
ENSMUST00000140866.9
ENSMUST00000108922.9
interferon regulatory factor 1
chr4_+_11704438 0.58 ENSMUST00000108304.9
GTP binding protein (gene overexpressed in skeletal muscle)
chr15_+_34238174 0.58 ENSMUST00000022867.5
ENSMUST00000226627.2
lysosomal-associated protein transmembrane 4B
chr2_+_128942900 0.57 ENSMUST00000103205.11
polymerase (RNA) I polypeptide B
chr7_+_29607917 0.57 ENSMUST00000186475.2
zinc finger protein 383
chr8_-_112064783 0.56 ENSMUST00000056157.14
ENSMUST00000120432.3
mixed lineage kinase domain-like
chr2_+_128942919 0.56 ENSMUST00000028874.8
polymerase (RNA) I polypeptide B
chr14_+_55842002 0.56 ENSMUST00000138037.2
interferon regulatory factor 9
chr17_-_45903410 0.56 ENSMUST00000166119.8
solute carrier family 29 (nucleoside transporters), member 1
chrX_-_139857424 0.55 ENSMUST00000033805.15
ENSMUST00000112978.2
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
chr10_-_17898838 0.53 ENSMUST00000220433.2
ABRA C-terminal like
chr6_+_127423779 0.53 ENSMUST00000112191.8
poly (ADP-ribose) polymerase family, member 11
chr8_-_112064393 0.52 ENSMUST00000145862.3
mixed lineage kinase domain-like
chr18_-_43610829 0.51 ENSMUST00000057110.11
eukaryotic translation initiation factor 3, subunit J2
chr8_+_111760521 0.51 ENSMUST00000034441.8
alanyl-tRNA synthetase
chr7_-_100232276 0.49 ENSMUST00000152876.3
ENSMUST00000150042.8
ENSMUST00000132888.9
mitochondrial ribosomal protein L48
chr11_+_69886652 0.48 ENSMUST00000101526.9
PHD finger protein 23
chr7_+_27290969 0.47 ENSMUST00000108344.9
thymoma viral proto-oncogene 2
chr4_+_99603877 0.47 ENSMUST00000097961.9
ENSMUST00000107004.9
ENSMUST00000139799.3
asparagine-linked glycosylation 6 (alpha-1,3,-glucosyltransferase)
chr15_+_88960327 0.46 ENSMUST00000165690.2
TraB domain containing
chr7_-_12787611 0.46 ENSMUST00000182490.2
myeloid zinc finger 1
chr1_+_134109888 0.45 ENSMUST00000156873.8
chitinase-like 1
chr2_+_101716577 0.45 ENSMUST00000028584.8
COMM domain containing 9
chr9_-_57460004 0.42 ENSMUST00000034856.15
mannose phosphate isomerase
chr3_-_96201248 0.40 ENSMUST00000029748.8
Fc receptor, IgG, high affinity I
chr17_+_28910302 0.39 ENSMUST00000004990.14
ENSMUST00000114754.8
ENSMUST00000062694.16
mitogen-activated protein kinase 14
chr7_+_45204317 0.39 ENSMUST00000107752.12
hydroxysteroid (17-beta) dehydrogenase 14
chr7_+_29515485 0.39 ENSMUST00000178162.3
ENSMUST00000032796.14
zinc finger protein 790
chr7_-_99770653 0.38 ENSMUST00000208670.2
ENSMUST00000032969.14
polymerase (DNA-directed), delta 3, accessory subunit
chr2_+_150590956 0.38 ENSMUST00000094467.6
ectonucleoside triphosphate diphosphohydrolase 6
chr6_-_48025845 0.38 ENSMUST00000095944.10
zinc finger protein 777
chr2_-_126341757 0.38 ENSMUST00000040128.12
ATPase, class I, type 8B, member 4
chr7_+_27291126 0.37 ENSMUST00000167435.8
thymoma viral proto-oncogene 2
chr19_+_36811615 0.36 ENSMUST00000025729.12
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
chr10_-_17898977 0.36 ENSMUST00000020002.9
ABRA C-terminal like
chrX_+_105059305 0.36 ENSMUST00000033582.5
cytochrome c oxidase subunit 7B
chr16_-_35691914 0.35 ENSMUST00000042665.9
poly (ADP-ribose) polymerase family, member 14
chr19_+_37184927 0.35 ENSMUST00000024078.15
ENSMUST00000112391.8
membrane associated ring-CH-type finger 5
chr5_+_52991351 0.35 ENSMUST00000031072.14
anaphase promoting complex subunit 4
chr11_-_75081284 0.35 ENSMUST00000044949.11
diphthamide biosynthesis 1
chr4_+_63478478 0.34 ENSMUST00000080336.4
transmembrane protein 268
chr7_-_108774367 0.34 ENSMUST00000207178.2
LIM domain only 1
chr14_+_56905698 0.34 ENSMUST00000116468.2
M-phase phosphoprotein 8
chr3_-_144412394 0.34 ENSMUST00000200532.2
SH3-domain GRB2-like B1 (endophilin)
chr16_-_91728162 0.34 ENSMUST00000139277.8
ENSMUST00000154661.8
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
chr4_-_129534403 0.33 ENSMUST00000084264.12
taxilin alpha
chr9_-_107158058 0.33 ENSMUST00000134682.3
mitogen-activated protein kinase-activated protein kinase 3
chr7_-_24016020 0.32 ENSMUST00000108436.8
ENSMUST00000032673.15
zinc finger protein 94
chr16_+_17326810 0.32 ENSMUST00000231292.2
leucine-zipper-like transcriptional regulator, 1
chr11_-_72106418 0.32 ENSMUST00000021157.9
mediator complex subunit 31
chr8_+_106052970 0.31 ENSMUST00000015000.12
ENSMUST00000098453.9
transmembrane protein 208
chr8_+_121463090 0.31 ENSMUST00000160943.3
ENSMUST00000047737.10
ENSMUST00000162658.8
interferon regulatory factor 8
chr16_+_19578981 0.30 ENSMUST00000079780.10
ENSMUST00000164397.8
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr5_-_5564730 0.30 ENSMUST00000115445.8
ENSMUST00000179804.8
ENSMUST00000125110.2
ENSMUST00000115446.8
claudin 12
chr1_+_171041539 0.29 ENSMUST00000005820.11
ENSMUST00000075469.12
ENSMUST00000155126.8
nuclear receptor subfamily 1, group I, member 3
chr2_-_127426588 0.29 ENSMUST00000110368.9
ENSMUST00000077422.12
zinc finger protein 661
chr3_+_84832783 0.28 ENSMUST00000107675.8
F-box and WD-40 domain protein 7
chr7_+_29794575 0.28 ENSMUST00000130526.2
ENSMUST00000108200.2
zinc finger protein 260
chr7_-_12788441 0.27 ENSMUST00000182087.2
myeloid zinc finger 1
chr17_-_45903494 0.27 ENSMUST00000163492.8
solute carrier family 29 (nucleoside transporters), member 1
chr2_-_84605732 0.26 ENSMUST00000023994.10
serine (or cysteine) peptidase inhibitor, clade G, member 1
chrX_+_158086253 0.26 ENSMUST00000112491.2
ribosomal protein S6 kinase polypeptide 3
chr16_+_17327076 0.26 ENSMUST00000232242.2
leucine-zipper-like transcriptional regulator, 1
chr11_-_59937302 0.26 ENSMUST00000000310.14
ENSMUST00000102693.9
ENSMUST00000148512.2
phosphatidylethanolamine N-methyltransferase
chr11_+_81926394 0.25 ENSMUST00000000193.6
chemokine (C-C motif) ligand 2
chr1_+_84936703 0.25 ENSMUST00000239195.2
predicted pseudogene 15433
chr17_+_28910393 0.24 ENSMUST00000124886.9
ENSMUST00000114758.9
mitogen-activated protein kinase 14
chr7_+_79836581 0.23 ENSMUST00000032754.9
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr18_+_21135079 0.23 ENSMUST00000234545.2
ring finger protein 138
chr4_-_129534853 0.22 ENSMUST00000046425.16
ENSMUST00000133803.8
taxilin alpha
chr7_-_99770280 0.22 ENSMUST00000208184.2
polymerase (DNA-directed), delta 3, accessory subunit
chr13_-_85437118 0.22 ENSMUST00000109552.3
RAS p21 protein activator 1
chr7_-_81479179 0.22 ENSMUST00000026093.9
BTB (POZ) domain containing 1
chr7_+_65343156 0.21 ENSMUST00000032726.14
ENSMUST00000107495.5
ENSMUST00000143508.3
ENSMUST00000129166.3
ENSMUST00000206517.2
ENSMUST00000206837.2
ENSMUST00000206628.2
ENSMUST00000206361.2
TM2 domain containing 3
chr13_-_85437201 0.21 ENSMUST00000223598.2
RAS p21 protein activator 1
chr2_-_155571279 0.20 ENSMUST00000040833.5
ER degradation enhancer, mannosidase alpha-like 2
chr3_-_51184730 0.20 ENSMUST00000195432.2
ENSMUST00000091144.11
ENSMUST00000156983.3
E74-like factor 2
chr8_+_11777721 0.19 ENSMUST00000210104.2
Rho guanine nucleotide exchange factor (GEF7)
chr4_-_129534752 0.19 ENSMUST00000132217.8
ENSMUST00000130017.2
ENSMUST00000154105.8
taxilin alpha
chr12_-_11315755 0.19 ENSMUST00000166117.4
ENSMUST00000219600.2
ENSMUST00000218487.2
GEN1, Holliday junction 5' flap endonuclease
chr8_-_111808488 0.19 ENSMUST00000188466.7
C-type lectin domain family 18, member A
chr8_-_111808674 0.19 ENSMUST00000039597.14
C-type lectin domain family 18, member A
chr9_-_59393893 0.18 ENSMUST00000171975.8
ariadne RBR E3 ubiquitin protein ligase 1
chrX_-_72974357 0.17 ENSMUST00000155597.2
ENSMUST00000114379.8
renin binding protein
chr4_+_120523758 0.17 ENSMUST00000094814.6
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
chr16_+_19578945 0.17 ENSMUST00000121344.8
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr11_+_101315893 0.17 ENSMUST00000040561.6
RUN domain containing 1
chr3_-_90398270 0.17 ENSMUST00000149884.2
SNAP-associated protein
chr16_-_17711950 0.16 ENSMUST00000155943.9
DiGeorge syndrome critical region gene 2
chr10_+_128139227 0.16 ENSMUST00000218315.2
ENSMUST00000219721.2
PAN2 poly(A) specific ribonuclease subunit
chr3_-_10505113 0.16 ENSMUST00000029047.12
ENSMUST00000195822.2
ENSMUST00000099223.11
sorting nexin 16
chr13_-_67903312 0.16 ENSMUST00000144183.3
zinc finger protein 85
chr11_-_98620200 0.15 ENSMUST00000126565.2
ENSMUST00000100500.9
ENSMUST00000017354.13
mediator complex subunit 24
chr2_+_3425159 0.15 ENSMUST00000100463.10
ENSMUST00000061852.12
ENSMUST00000102988.10
ENSMUST00000115066.8
DNA cross-link repair 1C
chr3_-_37180093 0.15 ENSMUST00000029275.6
interleukin 2
chr2_-_84605764 0.15 ENSMUST00000111641.2
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr7_+_23969822 0.15 ENSMUST00000108438.10
zinc finger protein 93
chr12_+_108859557 0.14 ENSMUST00000221377.2
WD repeat domain 25
chr5_+_134212836 0.14 ENSMUST00000016086.10
GTF2I repeat domain containing 2
chrX_-_8011952 0.14 ENSMUST00000115615.9
ENSMUST00000115616.8
ENSMUST00000115621.9
RNA binding motif (RNP1, RRM) protein 3
chr4_+_63478454 0.14 ENSMUST00000124332.8
ENSMUST00000150360.8
transmembrane protein 268
chr3_-_51184895 0.14 ENSMUST00000108051.8
ENSMUST00000108053.9
E74-like factor 2
chr10_+_128139191 0.14 ENSMUST00000005825.8
PAN2 poly(A) specific ribonuclease subunit
chr10_+_126877798 0.13 ENSMUST00000006915.14
ENSMUST00000120542.8
methyltransferase like 1
chr2_-_120801186 0.13 ENSMUST00000028728.6
ubiquitin protein ligase E3 component n-recognin 1
chrX_-_72974440 0.13 ENSMUST00000116578.8
renin binding protein
chr11_-_101315345 0.12 ENSMUST00000107257.8
ENSMUST00000107259.4
ENSMUST00000107252.9
ENSMUST00000093933.11
predicted gene, 27029
prostaglandin E synthase 3 like
chr16_-_31898088 0.12 ENSMUST00000023467.9
p21 (RAC1) activated kinase 2
chr5_+_14075281 0.12 ENSMUST00000073957.8
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr3_+_122039274 0.12 ENSMUST00000178826.8
glutamate-cysteine ligase, modifier subunit
chr12_+_86129329 0.12 ENSMUST00000054565.8
ENSMUST00000222821.2
ENSMUST00000222905.2
intraflagellar transport 43
chr16_-_20245138 0.11 ENSMUST00000079158.13
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr4_-_63965161 0.11 ENSMUST00000107377.10
tenascin C
chr3_+_99161070 0.11 ENSMUST00000029462.10
T-box 15
chr9_+_38629560 0.10 ENSMUST00000001544.12
ENSMUST00000118144.8
von Willebrand factor A domain containing 5A
chr11_+_81992662 0.10 ENSMUST00000000194.4
chemokine (C-C motif) ligand 12
chr15_+_25933632 0.10 ENSMUST00000228327.2
reticulophagy regulator 1
chrX_-_8118541 0.09 ENSMUST00000115594.8
ENSMUST00000115595.8
ENSMUST00000033513.10
FtsJ RNA methyltransferase homolog 1 (E. coli)
chr4_+_148686985 0.09 ENSMUST00000105701.9
ENSMUST00000052060.7
mannan-binding lectin serine peptidase 2
chr11_+_69886603 0.09 ENSMUST00000018716.10
PHD finger protein 23
chr7_+_45204350 0.09 ENSMUST00000210300.2
hydroxysteroid (17-beta) dehydrogenase 14
chr6_+_34575435 0.09 ENSMUST00000079391.10
ENSMUST00000142512.8
ENSMUST00000115027.8
ENSMUST00000115026.8
caldesmon 1
chr9_+_107173907 0.08 ENSMUST00000168260.2
cytokine inducible SH2-containing protein
chr6_-_65121892 0.08 ENSMUST00000031982.5
hematopoietic prostaglandin D synthase
chr4_+_114916703 0.08 ENSMUST00000162489.2
T cell acute lymphocytic leukemia 1
chr12_+_11315868 0.07 ENSMUST00000020931.6
structural maintenance of chromosomes 6
chr5_-_5564873 0.07 ENSMUST00000060947.14
claudin 12
chr9_+_123822000 0.07 ENSMUST00000039171.9
chemokine (C-C motif) receptor 3
chr5_+_75312939 0.06 ENSMUST00000202681.4
ENSMUST00000000476.15
platelet derived growth factor receptor, alpha polypeptide
chr9_+_107174081 0.06 ENSMUST00000167072.2
cytokine inducible SH2-containing protein
chr18_-_3280999 0.06 ENSMUST00000049942.13
cAMP responsive element modulator
chr8_+_71126012 0.06 ENSMUST00000146972.3
ENSMUST00000210071.2
ENSMUST00000210987.2
LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated
chr11_-_99877423 0.06 ENSMUST00000105050.4
keratin associated protein 16-1
chr8_-_71060911 0.05 ENSMUST00000210580.2
ENSMUST00000211608.2
ENSMUST00000049908.11
single stranded DNA binding protein 4
chr8_-_68363564 0.05 ENSMUST00000093468.12
pleckstrin and Sec7 domain containing 3
chr2_-_86640362 0.05 ENSMUST00000216117.2
olfactory receptor 141
chr9_+_105520154 0.05 ENSMUST00000190358.2
ENSMUST00000191268.7
ENSMUST00000065778.13
ENSMUST00000188784.2
phosphoinositide-3-kinase regulatory subunit 4
chr18_-_52662728 0.05 ENSMUST00000025409.9
lysyl oxidase
chr5_+_90708962 0.05 ENSMUST00000094615.8
ENSMUST00000200765.2
albumin superfamily member 1
chr2_-_101459274 0.05 ENSMUST00000099682.9
intraflagellar transport associated protein
chr7_-_100505486 0.05 ENSMUST00000139604.8
RELT tumor necrosis factor receptor
chr7_+_91321500 0.04 ENSMUST00000238619.2
ENSMUST00000238467.2
discs large MAGUK scaffold protein 2
chr18_-_3281089 0.04 ENSMUST00000139537.2
ENSMUST00000124747.8
cAMP responsive element modulator
chr5_-_34671236 0.04 ENSMUST00000114359.2
ENSMUST00000030991.14
ENSMUST00000087737.10
TNFAIP3 interacting protein 2
chr8_-_71229293 0.04 ENSMUST00000034296.15
phosphoinositide-3-kinase regulatory subunit 2
chr18_-_52662917 0.04 ENSMUST00000171470.8
lysyl oxidase
chr4_+_114945905 0.03 ENSMUST00000171877.8
ENSMUST00000177647.8
ENSMUST00000106548.9
ENSMUST00000030488.3
PDZK1 interacting protein 1
chr6_-_131607875 0.03 ENSMUST00000067597.5
taste receptor, type 2, member 130
chr3_-_88417251 0.03 ENSMUST00000149068.2
lamin A
chr13_-_42001075 0.03 ENSMUST00000179758.8
androgen dependent TFPI regulating protein
chr17_+_36134450 0.03 ENSMUST00000172846.2
flotillin 1
chr14_-_70864666 0.03 ENSMUST00000022694.17
dematin actin binding protein
chr1_-_37929414 0.03 ENSMUST00000139725.8
ENSMUST00000027257.10
MIT, microtubule interacting and transport, domain containing 1
chr7_-_30643444 0.03 ENSMUST00000062620.9
hepcidin antimicrobial peptide
chr5_+_67417908 0.03 ENSMUST00000037918.12
ENSMUST00000162543.8
ENSMUST00000161233.8
ENSMUST00000160352.8
transmembrane protein 33
chr5_-_72893941 0.03 ENSMUST00000169534.6
TXK tyrosine kinase
chr2_+_87082184 0.03 ENSMUST00000081986.5
olfactory receptor 1115
chr2_+_177834868 0.03 ENSMUST00000103065.2
phosphatase and actin regulator 3
chr15_-_37458768 0.02 ENSMUST00000116445.9
neurocalcin delta
chr5_-_6926523 0.02 ENSMUST00000164784.2
zinc finger protein 804B
chr15_-_93417380 0.02 ENSMUST00000109255.3
prickle planar cell polarity protein 1
chr4_+_43401232 0.02 ENSMUST00000125399.2
RUN and SH3 domain containing 2
chr10_+_129186434 0.02 ENSMUST00000077024.2
olfactory receptor 782
chr10_-_129574784 0.02 ENSMUST00000095245.2
olfactory receptor 806
chr6_+_21949986 0.02 ENSMUST00000149728.7
inhibitor of growth family, member 3
chr7_-_109330915 0.02 ENSMUST00000035372.3
achaete-scute family bHLH transcription factor 3
chrX_+_7594670 0.02 ENSMUST00000033489.8
PRA1 domain family 2
chr11_-_101316156 0.02 ENSMUST00000103102.10
prostaglandin E synthase 3 like
chr7_+_89780785 0.02 ENSMUST00000208684.2
phosphatidylinositol binding clathrin assembly protein
chr7_-_81356557 0.01 ENSMUST00000207983.2
homer scaffolding protein 2
chr11_-_58346806 0.01 ENSMUST00000055204.6
olfactory receptor 30
chr7_-_81356653 0.01 ENSMUST00000026922.15
homer scaffolding protein 2
chr8_-_125296435 0.01 ENSMUST00000238882.2
ENSMUST00000063278.7
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr3_+_122039206 0.01 ENSMUST00000029769.14
glutamate-cysteine ligase, modifier subunit
chr10_+_69761784 0.01 ENSMUST00000181974.8
ENSMUST00000182795.8
ENSMUST00000182437.8
ankyrin 3, epithelial
chr9_+_7464139 0.01 ENSMUST00000217651.3
matrix metallopeptidase 1a (interstitial collagenase)
chr18_+_52958382 0.01 ENSMUST00000238707.2
predicted gene, 50457
chr6_+_40941688 0.01 ENSMUST00000076638.7
RIKEN cDNA 1810009J06 gene
chr10_+_129298547 0.01 ENSMUST00000077836.3
olfactory receptor 787
chr1_+_36346804 0.01 ENSMUST00000126413.8
AT rich interactive domain 5A (MRF1-like)
chr7_+_91321694 0.01 ENSMUST00000238608.2
discs large MAGUK scaffold protein 2
chr10_+_129692389 0.01 ENSMUST00000064893.3
olfactory receptor 813

Network of associatons between targets according to the STRING database.

First level regulatory network of Stat1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0046967 cytosol to ER transport(GO:0046967)
0.4 1.4 GO:0044010 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) membrane disruption in other organism(GO:0051673) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
0.3 1.1 GO:0017126 nucleologenesis(GO:0017126)
0.3 1.1 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.3 0.8 GO:0046100 germinal center B cell differentiation(GO:0002314) adenosine catabolic process(GO:0006154) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101) purine deoxyribonucleoside metabolic process(GO:0046122) negative regulation of mucus secretion(GO:0070256)
0.2 0.8 GO:0060709 glycogen cell differentiation involved in embryonic placenta development(GO:0060709)
0.2 1.9 GO:1900227 positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.2 0.5 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.2 0.5 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.2 0.7 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.1 0.8 GO:0097473 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.1 0.8 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.1 0.4 GO:0001868 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.1 0.4 GO:0001788 antibody-dependent cellular cytotoxicity(GO:0001788)
0.1 0.6 GO:0035740 CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.1 0.8 GO:0015862 uridine transport(GO:0015862)
0.1 0.3 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
0.1 0.4 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.1 0.6 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.4 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.1 0.4 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 1.3 GO:0071493 cellular response to UV-B(GO:0071493)
0.1 0.3 GO:0002436 immune complex clearance by monocytes and macrophages(GO:0002436) monocyte homeostasis(GO:0035702) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265)
0.1 0.6 GO:2001184 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) positive regulation of interleukin-12 secretion(GO:2001184)
0.1 0.3 GO:0006624 vacuolar protein processing(GO:0006624)
0.1 0.6 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 0.3 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 0.5 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 0.2 GO:1904154 trimming of terminal mannose on B branch(GO:0036509) positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.1 0.6 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.1 1.4 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 0.3 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.0 0.3 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.3 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.2 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.0 0.7 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.3 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.3 GO:0044351 macropinocytosis(GO:0044351)
0.0 0.3 GO:0031145 anaphase-promoting complex-dependent catabolic process(GO:0031145)
0.0 0.1 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.0 0.6 GO:0045351 type I interferon biosynthetic process(GO:0045351)
0.0 1.2 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.1 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.0 0.2 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0 0.5 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.0 0.1 GO:0035747 natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501)
0.0 1.1 GO:0070266 necroptotic process(GO:0070266)
0.0 0.4 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.0 0.2 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.0 0.2 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.2 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.1 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.0 0.3 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291)
0.0 0.1 GO:0072277 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.0 0.5 GO:0006706 steroid catabolic process(GO:0006706)
0.0 0.1 GO:0051409 response to nitrosative stress(GO:0051409)
0.0 0.3 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130)
0.0 0.0 GO:0034757 negative regulation of iron ion transport(GO:0034757) negative regulation of iron ion transmembrane transport(GO:0034760)
0.0 0.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.3 GO:0032026 response to magnesium ion(GO:0032026)
0.0 0.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.0 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.1 GO:0061709 reticulophagy(GO:0061709)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0070557 PCNA-p21 complex(GO:0070557)
0.2 1.4 GO:0044279 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.2 1.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.2 1.5 GO:0042825 TAP complex(GO:0042825)
0.1 1.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 0.3 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 0.3 GO:0031251 PAN complex(GO:0031251)
0.0 0.8 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.0 0.5 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.3 GO:0070847 core mediator complex(GO:0070847)
0.0 0.3 GO:0044299 C-fiber(GO:0044299)
0.0 0.1 GO:0070722 Tle3-Aes complex(GO:0070722)
0.0 0.5 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.1 GO:0033193 Lsd1/2 complex(GO:0033193)
0.0 0.3 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.2 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.2 GO:0000322 storage vacuole(GO:0000322)
0.0 0.2 GO:0097413 Lewy body(GO:0097413)
0.0 0.1 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 0.4 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.4 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.8 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.3 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.6 GO:0051233 spindle midzone(GO:0051233)
0.0 0.4 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.1 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.3 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.2 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 0.1 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
0.4 1.3 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.3 1.1 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.2 0.5 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.2 0.5 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.1 1.4 GO:0008061 chitin binding(GO:0008061)
0.1 0.4 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 1.1 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 0.5 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.1 0.4 GO:0019770 IgG receptor activity(GO:0019770)
0.1 0.8 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 1.4 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.3 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 1.2 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) proteasome binding(GO:0070628)
0.0 0.1 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.0 0.8 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 0.6 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.4 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 1.2 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.8 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)
0.0 0.5 GO:0046527 glucosyltransferase activity(GO:0046527)
0.0 0.7 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.8 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.2 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.3 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 0.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.1 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.3 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.2 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.4 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.5 GO:0001848 complement binding(GO:0001848)
0.0 0.3 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 1.2 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.4 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.4 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.3 GO:0042171 lysophosphatidic acid acyltransferase activity(GO:0042171)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 0.6 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 1.6 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 1.0 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.1 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 1.0 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.5 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.6 PID AURORA A PATHWAY Aurora A signaling
0.0 0.3 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.6 PID IFNG PATHWAY IFN-gamma pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 1.6 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 1.5 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 1.3 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 1.6 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.6 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 3.4 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 1.4 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.7 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 1.0 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 1.1 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.8 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 1.8 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.9 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 1.3 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.3 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.8 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.3 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.4 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions