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avrg: GFI1 WT vs 36n/n vs KD

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Results for Tbp

Z-value: 6.36

Motif logo

Transcription factors associated with Tbp

Gene Symbol Gene ID Gene Info
ENSMUSG00000014767.18 TATA box binding protein

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tbpmm39_v1_chr17_+_15720150_157202220.553.3e-01Click!

Activity profile of Tbp motif

Sorted Z-values of Tbp motif

Promoter Log-likelihood Transcript Gene Gene Info
chr13_+_23765546 17.50 ENSMUST00000102968.3
H4 clustered histone 4
chr13_-_24118139 16.14 ENSMUST00000052776.4
H2B clustered histone 1
chr13_+_23936250 14.57 ENSMUST00000091703.3
H3 clustered histone 2
chr13_-_23882437 13.87 ENSMUST00000102967.3
H4 clustered histone 3
chr13_-_23806530 13.30 ENSMUST00000062045.4
H1.4 linker histone, cluster member
chr6_-_72935382 12.55 ENSMUST00000144337.2
thymosin, beta 10
chr13_+_21901791 12.35 ENSMUST00000188775.2
H3 clustered histone 10
chr3_+_96154001 12.27 ENSMUST00000176059.2
ENSMUST00000177796.2
H3 clustered histone 14
chr13_-_21934675 12.26 ENSMUST00000102983.2
H4 clustered histone 12
chr3_+_96175970 11.41 ENSMUST00000098843.3
H3 clustered histone 13
chr13_+_23728222 11.31 ENSMUST00000075558.5
H3 clustered histone 7
chr13_-_21967540 10.60 ENSMUST00000189457.2
H3 clustered histone 11
chr13_+_23947641 10.38 ENSMUST00000055770.4
H1.1 linker histone, cluster member
chr13_+_23759930 10.19 ENSMUST00000105105.4
H3 clustered histone 4
chr13_+_22017906 10.15 ENSMUST00000180288.2
H2B clustered histone 24
chr13_+_21971631 10.11 ENSMUST00000110473.3
ENSMUST00000102982.2
H2B clustered histone 22
chr14_-_51045182 9.71 ENSMUST00000227614.2
cyclin B1 interacting protein 1
chr13_-_23946359 9.16 ENSMUST00000091701.3
H3 clustered histone 1
chr13_-_23929490 9.07 ENSMUST00000091752.5
H3 clustered histone 3
chr13_+_23715220 8.64 ENSMUST00000102972.6
H4 clustered histone 8
chr13_+_23868175 7.96 ENSMUST00000018246.6
H2B clustered histone 4
chr3_+_96152813 7.91 ENSMUST00000078756.7
ENSMUST00000090779.4
H2A clustered histone 18
predicted gene 20634
chr13_+_21919225 7.90 ENSMUST00000087714.6
H4 clustered histone 11
chr13_+_21900554 6.85 ENSMUST00000070124.5
H2A clustered histone 13
chr17_+_36227869 6.15 ENSMUST00000151664.8
protein phosphatase 1, regulatory subunit 10
chr13_-_23867924 5.93 ENSMUST00000171127.4
H2A clustered histone 6
chr6_-_72935468 5.88 ENSMUST00000114050.8
thymosin, beta 10
chr13_-_22017677 5.81 ENSMUST00000081342.7
H2A clustered histone 24
chr13_-_21971388 5.53 ENSMUST00000091751.3
H2A clustered histone 22
chr3_-_20296337 5.50 ENSMUST00000001921.3
carboxypeptidase A3, mast cell
chr7_-_15993110 5.23 ENSMUST00000168818.2
complement component 5a receptor 1
chr2_+_129854256 3.94 ENSMUST00000110299.3
transglutaminase 3, E polypeptide
chr6_-_72935171 3.64 ENSMUST00000114049.2
thymosin, beta 10
chr1_-_171023798 3.32 ENSMUST00000111332.2
Purkinje cell protein 4-like 1
chr8_+_73072877 3.08 ENSMUST00000067912.8
Kruppel-like factor 2 (lung)
chr13_-_22225527 3.07 ENSMUST00000102977.4
H4 clustered histone 9
chr13_-_23755374 3.04 ENSMUST00000102969.6
H2A clustered histone 8
chr9_+_7558449 2.94 ENSMUST00000018765.4
matrix metallopeptidase 8
chr17_-_34043320 2.81 ENSMUST00000173879.8
ENSMUST00000166693.3
ENSMUST00000173019.8
ribosomal protein S28
chr15_-_76116245 2.80 ENSMUST00000167754.8
plectin
chr15_+_3300249 2.74 ENSMUST00000082424.12
ENSMUST00000159158.9
ENSMUST00000159216.10
ENSMUST00000160311.3
selenoprotein P
chr10_-_128462616 2.53 ENSMUST00000026420.7
ribosomal protein S26
chr13_+_23758555 2.48 ENSMUST00000090776.7
H2A clustered histone 7
chr2_+_111144362 2.45 ENSMUST00000219291.2
olfactory receptor 1280
chr2_+_152578164 2.42 ENSMUST00000038368.9
ENSMUST00000109824.2
inhibitor of DNA binding 1, HLH protein
chr11_-_4897991 2.38 ENSMUST00000093369.5
neurofilament, heavy polypeptide
chr7_+_30252687 2.30 ENSMUST00000044048.8
heat shock protein, alpha-crystallin-related, B6
chr9_+_57818243 2.21 ENSMUST00000216925.2
ENSMUST00000163329.2
ENSMUST00000213654.2
ENSMUST00000217132.2
ENSMUST00000216841.2
ENSMUST00000214086.2
ubiquitin-like 7 (bone marrow stromal cell-derived)
chr17_+_18269686 1.81 ENSMUST00000176802.3
vomeronasal 2, receptor 124
chr18_-_78166595 1.78 ENSMUST00000091813.12
solute carrier family 14 (urea transporter), member 1
chr5_-_125467063 1.74 ENSMUST00000136312.2
ubiquitin C
chr17_+_36227433 1.73 ENSMUST00000087211.9
protein phosphatase 1, regulatory subunit 10
chr15_-_102154874 1.66 ENSMUST00000063339.14
retinoic acid receptor, gamma
chr1_-_89942299 1.65 ENSMUST00000086882.8
ENSMUST00000097656.10
ankyrin repeat and SOCS box-containing 18
chr11_-_120604551 1.56 ENSMUST00000106154.8
ENSMUST00000106155.4
ENSMUST00000055424.13
ENSMUST00000026137.8
centromere protein X
chr2_-_51039112 1.51 ENSMUST00000154545.2
ENSMUST00000017288.9
Rho family GTPase 3
chr10_+_51367052 1.48 ENSMUST00000217705.2
ENSMUST00000078778.5
ENSMUST00000220182.2
ENSMUST00000220226.2
leukocyte immunoglobulin-like receptor, subfamily B, member 4A
chrX_+_158623460 1.48 ENSMUST00000112451.8
ENSMUST00000112453.9
SH3-domain kinase binding protein 1
chr8_-_3798941 1.47 ENSMUST00000012847.3
CD209a antigen
chr8_-_3798922 1.47 ENSMUST00000208960.2
ENSMUST00000207979.2
CD209a antigen
chr4_-_123507494 1.45 ENSMUST00000238866.2
microtubule-actin crosslinking factor 1
chr16_-_55642491 1.42 ENSMUST00000114458.8
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta
chr4_+_40269563 1.42 ENSMUST00000129758.3
small integral membrane protein 27
chr16_-_55659194 1.38 ENSMUST00000096026.9
ENSMUST00000036273.13
ENSMUST00000114457.8
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta
chr7_-_45109262 1.34 ENSMUST00000094434.13
ferritin light polypeptide 1
chr2_+_172090412 1.32 ENSMUST00000038532.2
melanocortin 3 receptor
chr1_+_93918231 1.20 ENSMUST00000097632.5
galactose-3-O-sulfotransferase 2C
chr11_-_73215442 1.19 ENSMUST00000021119.9
aspartoacylase
chr19_-_3464447 1.18 ENSMUST00000025842.8
ENSMUST00000237521.2
galanin and GMAP prepropeptide
chrX_+_102400061 1.17 ENSMUST00000116547.3
cysteine-rich hydrophobic domain 1
chr5_-_125467240 1.15 ENSMUST00000156249.2
ubiquitin C
chr2_+_90927053 1.13 ENSMUST00000132741.3
spleen focus forming virus (SFFV) proviral integration oncogene
chr2_-_166904625 1.10 ENSMUST00000128676.2
zinc finger, NFX1-type containing 1
chr5_-_91550853 1.07 ENSMUST00000121044.6
betacellulin, epidermal growth factor family member
chr5_-_71253107 1.04 ENSMUST00000197284.5
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2
chr7_+_108209994 1.04 ENSMUST00000209296.3
olfactory receptor 506
chr2_+_89804937 1.03 ENSMUST00000214630.2
ENSMUST00000111512.10
ENSMUST00000144710.3
ENSMUST00000216678.2
olfactory receptor 1260
chrX_+_72818003 0.99 ENSMUST00000002081.6
serine/arginine-rich protein specific kinase 3
chr11_+_33913013 0.99 ENSMUST00000020362.3
potassium large conductance calcium-activated channel, subfamily M, beta member 1
chr17_-_34043502 0.95 ENSMUST00000087342.13
ENSMUST00000173844.8
ribosomal protein S28
chr4_+_150572847 0.94 ENSMUST00000105680.9
arginine glutamic acid dipeptide (RE) repeats
chr1_+_163875783 0.91 ENSMUST00000027874.6
selectin, endothelial cell
chr1_-_134006847 0.89 ENSMUST00000020692.7
BTG anti-proliferation factor 2
chr13_-_93774469 0.88 ENSMUST00000099309.6
betaine-homocysteine methyltransferase
chr10_+_79540309 0.80 ENSMUST00000179781.8
ENSMUST00000067036.12
ENSMUST00000178383.8
basigin
chr7_-_140846328 0.78 ENSMUST00000106023.8
ENSMUST00000097952.9
ENSMUST00000026571.11
interferon regulatory factor 7
chr19_+_8866217 0.77 ENSMUST00000096251.10
ENSMUST00000191089.2
RIKEN cDNA 1810009A15 gene
predicted gene, 49416
chr9_+_44684206 0.76 ENSMUST00000002099.11
intraflagellar transport 46
chr11_+_62441992 0.75 ENSMUST00000019649.4
ubiquitin B
chr17_-_57535003 0.75 ENSMUST00000177046.2
ENSMUST00000024988.15
complement component 3
chr7_+_119773070 0.74 ENSMUST00000033201.7
ankyrin repeat and sterile alpha motif domain containing 4B
chr7_+_102790086 0.73 ENSMUST00000118682.3
olfactory receptor 588, pseudogene 1
chr14_-_47426863 0.73 ENSMUST00000089959.7
GTP cyclohydrolase 1
chr8_-_84467798 0.72 ENSMUST00000075843.13
ENSMUST00000109802.3
ENSMUST00000166939.8
ENSMUST00000002964.14
adhesion G protein-coupled receptor E5
chr9_+_57818384 0.67 ENSMUST00000217129.2
ubiquitin-like 7 (bone marrow stromal cell-derived)
chr7_+_28510350 0.66 ENSMUST00000174477.8
heterogeneous nuclear ribonucleoprotein L
chr11_+_94827050 0.63 ENSMUST00000001547.8
collagen, type I, alpha 1
chr1_+_93163553 0.62 ENSMUST00000062202.14
sushi, nidogen and EGF-like domains 1
chr15_+_98350469 0.62 ENSMUST00000217517.2
olfactory receptor 281
chr2_+_119449192 0.61 ENSMUST00000028771.8
nucleolar and spindle associated protein 1
chr13_+_17869727 0.61 ENSMUST00000221480.2
M-phase specific PLK1 intereacting protein
chr7_+_141276575 0.59 ENSMUST00000185406.8
mucin 2
chr13_+_30520416 0.57 ENSMUST00000222503.2
ENSMUST00000222370.2
ENSMUST00000066412.8
ENSMUST00000223201.2
angiotensin II receptor, type 1a
chr2_-_88590348 0.56 ENSMUST00000131038.4
ENSMUST00000213138.3
olfactory receptor 1199
chr10_+_73657689 0.56 ENSMUST00000064562.14
ENSMUST00000193174.6
ENSMUST00000105426.10
ENSMUST00000129404.9
ENSMUST00000131321.9
ENSMUST00000126920.9
ENSMUST00000147189.9
ENSMUST00000105424.10
ENSMUST00000092420.13
ENSMUST00000105429.10
ENSMUST00000193361.6
ENSMUST00000131724.9
ENSMUST00000152655.9
ENSMUST00000151116.9
ENSMUST00000155701.9
ENSMUST00000152819.9
ENSMUST00000125517.9
ENSMUST00000124046.8
ENSMUST00000146682.8
ENSMUST00000177107.8
ENSMUST00000149977.9
ENSMUST00000191854.6
protocadherin 15
chr12_+_33479604 0.54 ENSMUST00000020877.9
RNA polymerase I subunit F
chr16_+_48662894 0.54 ENSMUST00000238847.2
ENSMUST00000023329.7
resistin like alpha
chr3_+_142470806 0.54 ENSMUST00000029938.10
general transcription factor IIB
chr7_+_28510310 0.52 ENSMUST00000038572.15
heterogeneous nuclear ribonucleoprotein L
chr6_-_87958611 0.51 ENSMUST00000056403.7
H1.10 linker histone
chr11_-_50101592 0.51 ENSMUST00000143379.2
ENSMUST00000015981.12
ENSMUST00000102774.11
sequestosome 1
chr8_+_34582184 0.51 ENSMUST00000095345.5
membrane bound O-acyltransferase domain containing 4
chr9_-_81515865 0.51 ENSMUST00000183482.2
5-hydroxytryptamine (serotonin) receptor 1B
chr4_+_118965992 0.48 ENSMUST00000134105.8
ENSMUST00000144329.8
ENSMUST00000208090.2
solute carrier family 2 (facilitated glucose transporter), member 1
chr12_-_40249489 0.48 ENSMUST00000220951.2
leucine-rich single-pass membrane protein 1
chr13_+_23879775 0.48 ENSMUST00000041052.5
H1.6 linker histone, cluster member
chr4_-_41098174 0.44 ENSMUST00000055327.8
aquaporin 3
chr2_+_87854404 0.44 ENSMUST00000217006.2
olfactory receptor 1161
chr7_-_109380745 0.43 ENSMUST00000207400.2
ENSMUST00000033331.7
nuclear receptor interacting protein 3
chr19_+_34560922 0.43 ENSMUST00000102825.4
interferon-induced protein with tetratricopeptide repeats 3
chr4_+_63280675 0.43 ENSMUST00000075341.4
orosomucoid 2
chr1_+_153750081 0.43 ENSMUST00000055314.4
transmembrane epididymal protein 1B
chr17_+_34043536 0.43 ENSMUST00000048249.8
NADH:ubiquinone oxidoreductase subunit A7
chr11_-_73800125 0.42 ENSMUST00000215690.2
olfactory receptor 395
chr15_+_32244947 0.42 ENSMUST00000067458.7
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr3_-_20329823 0.41 ENSMUST00000011607.6
carboxypeptidase B1 (tissue)
chr2_+_13578738 0.41 ENSMUST00000141365.3
ENSMUST00000028062.8
vimentin
chr2_-_166904902 0.41 ENSMUST00000048988.14
zinc finger, NFX1-type containing 1
chr2_-_89671899 0.41 ENSMUST00000213833.2
olfactory receptor 1256
chr7_-_5496955 0.41 ENSMUST00000233742.2
ENSMUST00000233941.2
ENSMUST00000233390.2
ENSMUST00000233239.2
ENSMUST00000232789.2
ENSMUST00000086297.8
vomeronasal 2, receptor 28
chr7_-_141241632 0.40 ENSMUST00000239500.1
mucin 6, gastric
chr11_-_74228504 0.40 ENSMUST00000213831.2
olfactory receptor 410
chr2_+_36674288 0.37 ENSMUST00000213498.2
ENSMUST00000214909.3
ENSMUST00000215199.2
olfactory receptor 348
chr7_-_44393654 0.36 ENSMUST00000149011.9
zinc finger protein 473
chr18_-_15536747 0.36 ENSMUST00000079081.8
aquaporin 4
chr7_+_18721325 0.36 ENSMUST00000063563.9
nanos C2HC-type zinc finger 2
chr18_+_34757666 0.33 ENSMUST00000167161.9
kinesin family member 20A
chr6_-_41012435 0.33 ENSMUST00000031931.6
RIKEN cDNA 2210010C04 gene
chr6_+_90179768 0.32 ENSMUST00000078371.6
vomeronasal 1 receptor, A8
chr11_+_99755302 0.31 ENSMUST00000092694.4
predicted gene 11559
chr6_-_87649124 0.31 ENSMUST00000065997.5
aprataxin and PNKP like factor
chr11_-_53313950 0.30 ENSMUST00000036045.6
liver-expressed antimicrobial peptide 2
chr1_-_166475262 0.30 ENSMUST00000046662.8
predicted gene 4847
chr17_+_7592045 0.29 ENSMUST00000095726.11
ENSMUST00000128533.8
ENSMUST00000129709.8
ENSMUST00000147803.8
ENSMUST00000140192.8
ENSMUST00000138222.8
ENSMUST00000144861.2
t-complex protein 10a
chr11_-_77616103 0.28 ENSMUST00000078623.5
crystallin, beta A1
chr10_+_77697785 0.27 ENSMUST00000218443.2
predicted gene 3285
chr13_+_113931038 0.27 ENSMUST00000091201.7
ADP-ribosylation factor-like 15
chr11_-_74228857 0.27 ENSMUST00000214490.2
olfactory receptor 410
chr5_-_8672951 0.26 ENSMUST00000047485.15
ENSMUST00000115378.2
RUN domain containing 3B
chr9_-_70564403 0.25 ENSMUST00000213380.2
ENSMUST00000049031.6
MINDY lysine 48 deubiquitinase 2
chr2_+_158099986 0.24 ENSMUST00000109499.8
ENSMUST00000109500.8
ENSMUST00000065039.3
bactericidal permeablility increasing protein
chr1_+_171052623 0.24 ENSMUST00000111321.8
ENSMUST00000005824.12
ENSMUST00000111320.8
ENSMUST00000111319.2
apolipoprotein A-II
chr6_+_122603369 0.24 ENSMUST00000049644.9
developmental pluripotency-associated 3
chr15_+_10952418 0.23 ENSMUST00000022853.15
ENSMUST00000110523.2
C1q and tumor necrosis factor related protein 3
chr17_-_56424577 0.22 ENSMUST00000019808.12
perilipin 5
chr3_+_137329433 0.22 ENSMUST00000053855.8
DNA-damage-inducible transcript 4-like
chr12_+_102521225 0.22 ENSMUST00000021610.7
chromogranin A
chr6_-_57802040 0.22 ENSMUST00000127485.8
vesicular, overexpressed in cancer, prosurvival protein 1
chr11_-_58521327 0.22 ENSMUST00000214132.2
olfactory receptor 323
chr4_+_150939521 0.21 ENSMUST00000030811.2
ERBB receptor feedback inhibitor 1
chr7_+_31075005 0.21 ENSMUST00000179481.2
secretoglobin, family 1B, member 3
chr13_+_42454922 0.20 ENSMUST00000021796.9
endothelin 1
chr6_-_132291714 0.20 ENSMUST00000048686.9
proline-rich protein MP5
chr6_+_121323577 0.20 ENSMUST00000032200.16
solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12
chr6_+_42263609 0.19 ENSMUST00000238845.2
ENSMUST00000031894.13
chloride channel, voltage-sensitive 1
chr7_-_45109075 0.19 ENSMUST00000210864.2
ferritin light polypeptide 1
chr2_+_123931879 0.19 ENSMUST00000103241.8
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr7_+_45070244 0.19 ENSMUST00000072453.8
luteinizing hormone beta
chr17_-_67354971 0.18 ENSMUST00000224862.2
protein tyrosine phosphatase, receptor type, M
chr18_-_78166539 0.18 ENSMUST00000160292.8
solute carrier family 14 (urea transporter), member 1
chr15_-_101694895 0.18 ENSMUST00000071104.6
keratin 72
chr8_-_110894836 0.18 ENSMUST00000003754.8
ENSMUST00000212297.2
calbindin 2
chr11_+_106256298 0.18 ENSMUST00000009354.10
proline rich 29
chr2_-_35994072 0.18 ENSMUST00000112961.10
ENSMUST00000112966.10
LIM homeobox protein 6
chrX_+_72271878 0.17 ENSMUST00000105111.4
factor 8-associated gene A
chr7_+_45175754 0.17 ENSMUST00000211227.2
ENSMUST00000051810.15
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4
chr14_+_67982630 0.17 ENSMUST00000223929.2
ENSMUST00000111095.4
gonadotropin releasing hormone 1
chr4_+_128653051 0.17 ENSMUST00000030585.8
alpha 1,3-galactosyltransferase 2 (isoglobotriaosylceramide synthase)
chr2_-_6217844 0.16 ENSMUST00000042658.5
enoyl Coenzyme A hydratase domain containing 3
chr18_-_35836161 0.16 ENSMUST00000025208.7
DnaJ heat shock protein family (Hsp40) member C18
chr6_+_70640233 0.16 ENSMUST00000103400.3
immunoglobulin kappa chain variable 3-5
chr6_-_130363837 0.16 ENSMUST00000032288.6
killer cell lectin-like receptor, subfamily A, member 1
chr10_-_79875479 0.16 ENSMUST00000004786.10
polymerase (RNA) II (DNA directed) polypeptide E
chr2_-_31700592 0.15 ENSMUST00000057407.3
pyroglutamylated RFamide peptide
chr17_+_34174782 0.15 ENSMUST00000025178.17
VPS52 GARP complex subunit
chr5_+_88073438 0.15 ENSMUST00000001667.13
ENSMUST00000113267.8
casein kappa
chr3_-_75389047 0.15 ENSMUST00000193989.4
ENSMUST00000203169.3
WD repeat domain 49
chr2_-_101459303 0.15 ENSMUST00000111231.10
intraflagellar transport associated protein
chr1_+_127657142 0.15 ENSMUST00000038006.8
amino carboxymuconate semialdehyde decarboxylase
chrM_+_7779 0.14 ENSMUST00000082408.1
mitochondrially encoded ATP synthase 6
chr2_+_154149122 0.14 ENSMUST00000088921.6
BPI fold containing family B, member 9B
chr2_+_13579092 0.14 ENSMUST00000193675.2
vimentin
chr6_-_113577606 0.14 ENSMUST00000035870.5
Fancd2 opposite strand
chr4_-_63663344 0.13 ENSMUST00000239480.2
ENSMUST00000062246.8
tumor necrosis factor (ligand) superfamily, member 15
chr8_+_124138163 0.13 ENSMUST00000071134.4
ENSMUST00000212743.2
tubulin, beta 3 class III
chr4_-_40269778 0.13 ENSMUST00000042575.7
topoisomerase I binding, arginine/serine-rich
chr9_+_108385247 0.13 ENSMUST00000207810.2
ENSMUST00000207862.2
ENSMUST00000208581.2
ENSMUST00000134939.9
ENSMUST00000207713.2
glutaminyl-tRNA synthetase
chr17_-_56424265 0.13 ENSMUST00000113072.3
perilipin 5
chr5_+_48140480 0.13 ENSMUST00000173107.8
ENSMUST00000174313.8
ENSMUST00000174421.8
ENSMUST00000170109.9
slit guidance ligand 2
chr19_+_16416664 0.13 ENSMUST00000237350.2
guanine nucleotide binding protein, alpha 14

Network of associatons between targets according to the STRING database.

First level regulatory network of Tbp

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.7 5.2 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.5 8.8 GO:0051026 chiasma assembly(GO:0051026)
0.5 5.5 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
0.4 3.1 GO:0034616 response to laminar fluid shear stress(GO:0034616) cellular response to laminar fluid shear stress(GO:0071499)
0.3 1.7 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.3 1.0 GO:1903412 response to bile acid(GO:1903412) cellular response to bile acid(GO:1903413)
0.3 2.0 GO:0071918 urea transmembrane transport(GO:0071918)
0.3 2.4 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.3 1.2 GO:0051795 positive regulation of catagen(GO:0051795)
0.2 0.9 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.2 0.6 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.2 0.6 GO:0050973 detection of mechanical stimulus involved in equilibrioception(GO:0050973)
0.2 0.8 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.2 2.8 GO:0031581 hemidesmosome assembly(GO:0031581)
0.2 0.7 GO:0014916 regulation of lung blood pressure(GO:0014916)
0.2 1.2 GO:0006083 acetate metabolic process(GO:0006083)
0.2 0.8 GO:0070295 renal water absorption(GO:0070295)
0.1 0.7 GO:1904970 brush border assembly(GO:1904970)
0.1 0.9 GO:0071267 amino acid salvage(GO:0043102) L-methionine salvage(GO:0071267)
0.1 0.8 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.1 0.5 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.1 4.0 GO:0031424 keratinization(GO:0031424)
0.1 0.7 GO:0021886 hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.1 1.2 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.1 1.1 GO:0090241 hypermethylation of CpG island(GO:0044027) negative regulation of histone H4 acetylation(GO:0090241) apoptotic process involved in patterning of blood vessels(GO:1902262)
0.1 0.6 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 1.6 GO:0051382 kinetochore assembly(GO:0051382)
0.1 0.5 GO:1904798 positive regulation of core promoter binding(GO:1904798)
0.1 0.4 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.1 1.3 GO:0035810 positive regulation of urine volume(GO:0035810)
0.1 0.2 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.1 0.4 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1 0.4 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.1 0.5 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.1 0.2 GO:0060720 spongiotrophoblast cell proliferation(GO:0060720) cell proliferation involved in embryonic placenta development(GO:0060722)
0.1 1.4 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.1 0.2 GO:0010901 regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
0.1 0.2 GO:1901536 negative regulation of DNA demethylation(GO:1901536)
0.1 3.8 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.1 0.3 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.1 0.2 GO:2000354 regulation of ovarian follicle development(GO:2000354)
0.1 0.2 GO:0010616 negative regulation of cardiac muscle adaptation(GO:0010616) negative regulation of cardiac muscle hypertrophy in response to stress(GO:1903243)
0.1 1.3 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.3 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.4 GO:0044838 cell quiescence(GO:0044838)
0.0 0.1 GO:0021966 corticospinal neuron axon guidance(GO:0021966) regulation of retinal ganglion cell axon guidance(GO:0090259) negative regulation of neutrophil migration(GO:1902623)
0.0 1.8 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 0.9 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0 0.5 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 1.3 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.1 GO:0052203 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.0 0.9 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.6 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.4 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.2 GO:0009992 cellular water homeostasis(GO:0009992)
0.0 0.6 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.4 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.3 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.2 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.0 1.5 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.0 0.1 GO:0060450 positive regulation of hindgut contraction(GO:0060450)
0.0 0.8 GO:0060285 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.2 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.2 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.1 GO:0070368 positive regulation of hepatocyte differentiation(GO:0070368)
0.0 0.1 GO:1900019 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0 0.2 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 0.1 GO:0042414 epinephrine metabolic process(GO:0042414)
0.0 0.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.4 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.0 0.0 GO:0003097 renal water transport(GO:0003097) glycerol transport(GO:0015793)
0.0 0.0 GO:0032696 negative regulation of interleukin-13 production(GO:0032696)
0.0 0.1 GO:0044704 mating plug formation(GO:0042628) single-organism reproductive behavior(GO:0044704) post-mating behavior(GO:0045297)
0.0 0.1 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.0 1.0 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 1.0 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.1 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.1 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894)
0.0 0.0 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.0 0.0 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.0 2.8 GO:0042129 regulation of T cell proliferation(GO:0042129)
0.0 0.2 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 7.9 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.4 1.6 GO:0071821 FANCM-MHF complex(GO:0071821)
0.2 0.6 GO:0005584 collagen type I trimer(GO:0005584)
0.2 2.4 GO:0005883 neurofilament(GO:0005883)
0.2 0.5 GO:0044753 amphisome(GO:0044753)
0.1 3.9 GO:0001533 cornified envelope(GO:0001533)
0.1 0.5 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 0.5 GO:0045098 type III intermediate filament(GO:0045098)
0.1 0.7 GO:0031983 vesicle lumen(GO:0031983)
0.1 1.8 GO:0045120 pronucleus(GO:0045120)
0.0 7.9 GO:0000795 synaptonemal complex(GO:0000795)
0.0 1.0 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.2 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.1 GO:0042643 actomyosin, actin portion(GO:0042643)
0.0 0.8 GO:0002080 acrosomal membrane(GO:0002080)
0.0 2.7 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.3 GO:0044754 autolysosome(GO:0044754)
0.0 0.8 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.1 GO:0060473 cortical granule(GO:0060473)
0.0 0.2 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.2 GO:0042627 chylomicron(GO:0042627)
0.0 0.1 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.2 GO:0001847 opsonin receptor activity(GO:0001847)
0.4 22.1 GO:0003785 actin monomer binding(GO:0003785)
0.4 1.3 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.4 0.4 GO:0015254 glycerol channel activity(GO:0015254)
0.4 1.2 GO:0019807 aspartoacylase activity(GO:0019807)
0.4 3.9 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.3 2.0 GO:0015265 urea channel activity(GO:0015265)
0.3 1.0 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.2 5.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.2 7.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.2 3.7 GO:0005537 mannose binding(GO:0005537)
0.2 1.2 GO:0004966 galanin receptor activity(GO:0004966)
0.1 0.6 GO:0004945 angiotensin type II receptor activity(GO:0004945) bradykinin receptor binding(GO:0031711)
0.1 0.9 GO:0008172 S-methyltransferase activity(GO:0008172)
0.1 2.4 GO:0015643 toxic substance binding(GO:0015643)
0.1 2.4 GO:0070628 proteasome binding(GO:0070628)
0.1 3.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.4 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.1 1.2 GO:1990715 mRNA CDS binding(GO:1990715)
0.1 1.7 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 0.9 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.7 GO:0019238 cyclohydrolase activity(GO:0019238)
0.1 0.4 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 1.1 GO:0051525 NFAT protein binding(GO:0051525)
0.1 2.8 GO:0030506 ankyrin binding(GO:0030506)
0.1 0.3 GO:0071796 K6-linked polyubiquitin binding(GO:0071796)
0.1 0.2 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.1 0.2 GO:0001962 alpha-1,3-galactosyltransferase activity(GO:0001962)
0.1 0.2 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.1 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.0 0.5 GO:0035473 lipase binding(GO:0035473)
0.0 0.6 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.5 GO:0051378 serotonin binding(GO:0051378)
0.0 0.4 GO:0015288 porin activity(GO:0015288)
0.0 1.0 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.2 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.3 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.1 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
0.0 0.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 1.1 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0070002 glutamic-type peptidase activity(GO:0070002)
0.0 1.0 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.1 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.5 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.2 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 1.2 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.4 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.2 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 4.4 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 2.3 GO:0002020 protease binding(GO:0002020)
0.0 0.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0010853 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.1 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.8 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.7 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.4 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 1.1 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.2 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 1.5 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.1 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.5 PID IL1 PATHWAY IL1-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 3.0 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 0.8 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 2.2 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 0.8 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 0.7 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.5 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 1.0 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.5 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.6 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 5.9 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.3 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.8 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 1.0 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.1 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.0 1.1 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.6 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.4 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.1 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 1.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.7 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.4 REACTOME KINESINS Genes involved in Kinesins
0.0 0.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine