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avrg: GFI1 WT vs 36n/n vs KD

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Results for Tcf3

Z-value: 0.93

Motif logo

Transcription factors associated with Tcf3

Gene Symbol Gene ID Gene Info
ENSMUSG00000020167.15 transcription factor 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tcf3mm39_v1_chr10_-_80269436_80269488-0.983.3e-03Click!

Activity profile of Tcf3 motif

Sorted Z-values of Tcf3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_96175970 1.34 ENSMUST00000098843.3
H3 clustered histone 13
chr13_+_23728222 1.27 ENSMUST00000075558.5
H3 clustered histone 7
chr1_+_177269845 1.15 ENSMUST00000195002.2
zinc finger and BTB domain containing 18
chr15_-_101268036 0.78 ENSMUST00000077196.6
keratin 80
chr10_+_127612243 0.75 ENSMUST00000136223.2
ENSMUST00000052652.7
retinol dehydrogenase 9
chr8_-_123425805 0.70 ENSMUST00000127984.9
CBFA2/RUNX1 translocation partner 3
chr1_-_44258112 0.69 ENSMUST00000054801.4
methyltransferase like 21E
chr13_+_23935088 0.66 ENSMUST00000078369.3
H2A clustered histone 4
chr7_-_125681577 0.63 ENSMUST00000073935.7
GSG1-like
chr11_+_115790768 0.60 ENSMUST00000152171.8
small integral membrane protein 5
chr2_-_18053158 0.55 ENSMUST00000066885.6
SKI/DACH domain containing 1
chr2_-_91854844 0.52 ENSMUST00000028663.5
cAMP responsive element binding protein 3-like 1
chr1_-_79649683 0.52 ENSMUST00000162342.8
adaptor-related protein complex AP-1, sigma 3
chr7_-_12342715 0.48 ENSMUST00000233892.2
vomeronasal 2, receptor 53
chr5_-_66308421 0.46 ENSMUST00000200775.4
ENSMUST00000094756.11
RNA binding motif protein 47
chr5_-_140612993 0.46 ENSMUST00000199157.2
tweety family member 3
chr19_+_8975249 0.45 ENSMUST00000236390.2
AHNAK nucleoprotein (desmoyokin)
chr5_-_137598912 0.45 ENSMUST00000111007.8
ENSMUST00000133705.2
motile sperm domain containing 3
chr10_-_41894360 0.43 ENSMUST00000162405.8
ENSMUST00000095729.11
ENSMUST00000161081.2
ENSMUST00000160262.9
armadillo repeat containing 2
chr1_-_171061902 0.43 ENSMUST00000079957.12
Fc receptor, IgE, high affinity I, gamma polypeptide
chr17_-_71309012 0.43 ENSMUST00000128179.2
ENSMUST00000150456.2
ENSMUST00000233357.2
ENSMUST00000233417.2
myosin, light chain 12A, regulatory, non-sarcomeric
predicted gene, 49909
chr7_-_12468931 0.43 ENSMUST00000233304.2
ENSMUST00000233373.2
ENSMUST00000233874.2
ENSMUST00000233902.2
vomeronasal 2, receptor 56
chr13_-_111945499 0.40 ENSMUST00000109267.9
mitogen-activated protein kinase kinase kinase 1
chr1_-_160134873 0.40 ENSMUST00000193185.6
RAB GTPase activating protein 1-like
chr4_+_140633646 0.40 ENSMUST00000030765.7
peptidyl arginine deiminase, type II
chr2_-_143853122 0.39 ENSMUST00000016072.12
ENSMUST00000037875.6
ribosome binding protein 1
chr10_-_120037464 0.38 ENSMUST00000020448.11
interleukin-1 receptor-associated kinase 3
chr2_+_71811526 0.38 ENSMUST00000090826.12
ENSMUST00000102698.10
Rap guanine nucleotide exchange factor (GEF) 4
chr6_+_122803624 0.37 ENSMUST00000203075.2
forkhead box J2
chr13_-_23867924 0.37 ENSMUST00000171127.4
H2A clustered histone 6
chr17_-_23964807 0.37 ENSMUST00000046525.10
kringle containing transmembrane protein 2
chr5_-_113968483 0.36 ENSMUST00000100874.6
selectin, platelet (p-selectin) ligand
chr2_+_90865958 0.34 ENSMUST00000111445.10
ENSMUST00000111446.10
ENSMUST00000050323.6
receptor-associated protein of the synapse
chr6_+_82379456 0.33 ENSMUST00000032122.11
tachykinin receptor 1
chrX_-_72913410 0.33 ENSMUST00000066576.12
ENSMUST00000114430.8
L1 cell adhesion molecule
chr7_+_3339059 0.32 ENSMUST00000096744.8
myeloid-associated differentiation marker
chr6_+_82379768 0.32 ENSMUST00000203775.2
tachykinin receptor 1
chr4_+_119671688 0.31 ENSMUST00000106307.9
human immunodeficiency virus type I enhancer binding protein 3
chr7_+_3339077 0.31 ENSMUST00000203566.3
myeloid-associated differentiation marker
chr8_+_66419809 0.31 ENSMUST00000072482.13
membrane associated ring-CH-type finger 1
chr1_+_59802543 0.31 ENSMUST00000087435.7
bone morphogenetic protein receptor, type II (serine/threonine kinase)
chr12_-_100995102 0.31 ENSMUST00000223097.2
coiled-coil domain containing 88C
chr7_-_114162125 0.30 ENSMUST00000211506.2
ENSMUST00000119712.8
ENSMUST00000032908.15
cytochrome P450, family 2, subfamily r, polypeptide 1
chr1_-_171061838 0.29 ENSMUST00000193973.2
Fc receptor, IgE, high affinity I, gamma polypeptide
chr15_-_71906051 0.29 ENSMUST00000159993.8
collagen, type XXII, alpha 1
chr2_-_18053595 0.29 ENSMUST00000142856.2
SKI/DACH domain containing 1
chr1_-_172460497 0.29 ENSMUST00000027826.7
dual specificity phosphatase 23
chr2_-_168072295 0.28 ENSMUST00000154111.8
dolichol-phosphate (beta-D) mannosyltransferase 1
chr7_-_126224848 0.28 ENSMUST00000032961.4
nuclear protein transcription regulator 1
chr5_+_123280250 0.28 ENSMUST00000174836.8
ENSMUST00000163030.9
SET domain containing 1B
chrX_-_47297436 0.28 ENSMUST00000037960.11
zinc finger, DHHC domain containing 9
chrX_+_137815171 0.28 ENSMUST00000064937.14
ENSMUST00000113052.8
Nik related kinase
chr13_+_109397184 0.28 ENSMUST00000153234.8
phosphodiesterase 4D, cAMP specific
chr10_-_75396164 0.28 ENSMUST00000051129.10
leucine rich repeat containing 75B
chr17_-_57394718 0.27 ENSMUST00000071135.6
tubulin, beta 4A class IVA
chr5_+_99002293 0.27 ENSMUST00000031278.6
ENSMUST00000200388.2
bone morphogenetic protein 3
chr10_+_127637015 0.27 ENSMUST00000071646.2
retinol dehydrogenase 16
chr7_+_44465714 0.26 ENSMUST00000208172.2
nucleoporin 62
chr17_+_47747657 0.26 ENSMUST00000150819.3
expressed sequence AI661453
chr5_-_25305621 0.26 ENSMUST00000030784.14
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr1_+_87254729 0.26 ENSMUST00000172794.8
ENSMUST00000164992.9
ENSMUST00000173173.8
GRB10 interacting GYF protein 2
chr7_+_142025817 0.26 ENSMUST00000105966.2
lymphocyte specific 1
chr2_-_103315483 0.25 ENSMUST00000028610.10
catalase
chr9_+_21746785 0.25 ENSMUST00000058777.8
angiopoietin-like 8
chr7_-_28001624 0.25 ENSMUST00000108315.4
delta like canonical Notch ligand 3
chr2_-_33261411 0.25 ENSMUST00000131298.7
ENSMUST00000091039.5
ENSMUST00000042615.13
Ral GEF with PH domain and SH3 binding motif 1
chrX_-_7242065 0.25 ENSMUST00000191497.2
ENSMUST00000115744.2
ubiquitin specific peptidase 27, X chromosome
chr9_+_56979307 0.25 ENSMUST00000169879.8
transcriptional regulator, SIN3A (yeast)
chr9_-_123680726 0.24 ENSMUST00000084715.14
FYVE and coiled-coil domain containing 1
chr12_+_112978051 0.24 ENSMUST00000223502.2
ENSMUST00000084891.5
ENSMUST00000220541.2
phosphofurin acidic cluster sorting protein 2
chr3_+_94305824 0.24 ENSMUST00000050975.6
leucine rich repeat and Ig domain containing 4
chr2_+_156562956 0.24 ENSMUST00000109566.9
ENSMUST00000146412.9
ENSMUST00000177013.8
ENSMUST00000171030.9
DLG associated protein 4
chr7_+_119495058 0.24 ENSMUST00000106518.9
ENSMUST00000207270.2
ENSMUST00000208424.2
ENSMUST00000208202.2
ENSMUST00000054440.11
LYR motif containing 1
chr10_-_127016448 0.24 ENSMUST00000222911.3
ENSMUST00000095270.3
solute carrier family 26, member 10
chr8_-_32499513 0.24 ENSMUST00000208205.3
neuregulin 1
chr4_+_132968082 0.23 ENSMUST00000030677.7
mitogen-activated protein kinase kinase kinase 6
chr8_-_32499556 0.23 ENSMUST00000207470.3
ENSMUST00000207417.3
ENSMUST00000238826.2
neuregulin 1
chr5_+_3978032 0.23 ENSMUST00000143365.8
A kinase (PRKA) anchor protein (yotiao) 9
chr12_-_100995242 0.23 ENSMUST00000085096.10
coiled-coil domain containing 88C
chr5_+_21748523 0.22 ENSMUST00000035651.6
leucine rich repeat containing 17
chr14_+_34395845 0.22 ENSMUST00000048263.14
WAPL cohesin release factor
chr7_+_121888520 0.22 ENSMUST00000064989.12
ENSMUST00000064921.5
protein kinase C, beta
chr5_+_31046196 0.22 ENSMUST00000069705.11
ENSMUST00000201917.4
ENSMUST00000201168.4
ENSMUST00000202060.4
ENSMUST00000201225.4
ENSMUST00000114700.9
ATP/GTP binding protein-like 5
chr13_-_92268156 0.22 ENSMUST00000151408.9
ENSMUST00000216219.2
RAS protein-specific guanine nucleotide-releasing factor 2
chr7_+_127475968 0.22 ENSMUST00000131000.2
zinc finger protein 646
chr14_-_55150547 0.22 ENSMUST00000228495.3
ENSMUST00000228119.3
ENSMUST00000050772.10
ENSMUST00000231305.2
solute carrier family 22 (organic cation transporter), member 17
chr2_+_102488985 0.22 ENSMUST00000080210.10
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr7_+_142025575 0.22 ENSMUST00000038946.9
lymphocyte specific 1
chr8_+_83891972 0.22 ENSMUST00000034145.11
TBC1 domain family, member 9
chr19_+_47167444 0.22 ENSMUST00000235326.2
neuralized E3 ubiquitin protein ligase 1A
chr11_-_100288566 0.21 ENSMUST00000001592.15
ENSMUST00000107403.2
junction plakoglobin
chr7_-_30251680 0.21 ENSMUST00000215288.2
ENSMUST00000108165.8
ENSMUST00000153594.3
proline and serine rich 3
chr15_+_84553801 0.20 ENSMUST00000171460.8
proline rich 5 (renal)
chr1_+_59296065 0.20 ENSMUST00000160662.8
ENSMUST00000114248.3
cyclin-dependent kinase 15
chr11_+_29323618 0.20 ENSMUST00000040182.13
ENSMUST00000109477.2
coiled coil domain containing 88A
chr9_+_44893077 0.20 ENSMUST00000034602.9
CD3 antigen, delta polypeptide
chr6_+_29531247 0.20 ENSMUST00000164922.3
interferon regulatory factor 5
chrX_-_47297746 0.20 ENSMUST00000088935.4
zinc finger, DHHC domain containing 9
chr7_-_45071897 0.20 ENSMUST00000210271.2
RuvB-like protein 2
chr2_+_174171979 0.20 ENSMUST00000109083.2
GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus
chr5_-_66308666 0.20 ENSMUST00000201561.4
RNA binding motif protein 47
chr10_+_58649181 0.20 ENSMUST00000135526.9
ENSMUST00000153031.2
SH3 domain containing ring finger 3
chr5_-_31065036 0.19 ENSMUST00000132034.5
ENSMUST00000132253.5
oligosaccharyltransferase complex subunit 4 (non-catalytic)
chr4_-_93223746 0.19 ENSMUST00000066774.6
tumor suppressor candidate 1
chr7_+_126380655 0.19 ENSMUST00000172352.8
ENSMUST00000094037.5
T-box 6
chr19_+_4282487 0.19 ENSMUST00000235306.2
polymerase (DNA-directed), delta 4
chr13_+_55097200 0.19 ENSMUST00000026994.14
ENSMUST00000109994.9
unc-5 netrin receptor A
chr16_+_14523696 0.19 ENSMUST00000023356.8
snail family zinc finger 2
chr15_+_61858883 0.18 ENSMUST00000159338.2
myelocytomatosis oncogene
chr14_+_26761023 0.18 ENSMUST00000223942.2
interleukin 17 receptor D
chr15_-_77653979 0.18 ENSMUST00000229259.2
myosin, heavy polypeptide 9, non-muscle
chr16_+_95058417 0.18 ENSMUST00000113861.8
ENSMUST00000113854.8
ENSMUST00000113862.8
ENSMUST00000037154.14
ENSMUST00000113855.8
potassium inwardly-rectifying channel, subfamily J, member 15
chr11_+_69806866 0.18 ENSMUST00000134581.2
G protein pathway suppressor 2
chr4_+_107825529 0.18 ENSMUST00000106713.5
ENSMUST00000238795.2
solute carrier family 1 (glutamate transporter), member 7
chrX_+_167819606 0.18 ENSMUST00000087016.11
ENSMUST00000112129.8
ENSMUST00000112131.9
Rho GTPase activating protein 6
chr12_-_100995305 0.17 ENSMUST00000068411.5
coiled-coil domain containing 88C
chr7_-_122969064 0.17 ENSMUST00000207010.2
ENSMUST00000167309.8
ENSMUST00000205262.2
ENSMUST00000106442.9
ENSMUST00000098060.5
Rho GTPase activating protein 17
chr2_-_168072493 0.17 ENSMUST00000109193.8
dolichol-phosphate (beta-D) mannosyltransferase 1
chr2_+_156562929 0.17 ENSMUST00000131157.9
DLG associated protein 4
chr10_-_7162196 0.17 ENSMUST00000015346.12
Cnksr family member 3
chrX_-_135769285 0.17 ENSMUST00000058814.7
RAB9B, member RAS oncogene family
chr2_-_30364219 0.17 ENSMUST00000065134.4
immediate early response 5-like
chr12_-_4527138 0.17 ENSMUST00000085814.5
nuclear receptor coactivator 1
chr16_-_55642491 0.17 ENSMUST00000114458.8
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta
chr5_+_117552042 0.17 ENSMUST00000180430.2
kinase suppressor of ras 2
chr13_-_49301407 0.17 ENSMUST00000162581.8
ENSMUST00000110097.9
ENSMUST00000049265.15
ENSMUST00000035538.13
ENSMUST00000110096.8
ENSMUST00000091623.10
WNK lysine deficient protein kinase 2
chr11_+_115790951 0.16 ENSMUST00000142089.2
ENSMUST00000131566.2
small integral membrane protein 5
chr2_-_33321306 0.16 ENSMUST00000113158.8
zinc finger and BTB domain containing 34
chr1_-_39517761 0.16 ENSMUST00000193823.2
ENSMUST00000054462.11
TBC1 domain family, member 8
chrX_+_7439839 0.16 ENSMUST00000144719.9
ENSMUST00000234896.2
Foxp3 regulating long intergenic noncoding RNA
forkhead box P3
chr8_+_106002772 0.16 ENSMUST00000014920.8
nucleolar protein 3 (apoptosis repressor with CARD domain)
chr17_+_29077385 0.16 ENSMUST00000056866.8
patatin-like phospholipase domain containing 1
chr10_-_80096842 0.16 ENSMUST00000105363.8
guanidinoacetate methyltransferase
chr16_+_17269845 0.16 ENSMUST00000006293.5
ENSMUST00000231228.2
v-crk avian sarcoma virus CT10 oncogene homolog-like
chr11_-_106469938 0.16 ENSMUST00000103070.3
testis expressed gene 2
chr2_+_156562989 0.16 ENSMUST00000000094.14
DLG associated protein 4
chr18_+_36481706 0.16 ENSMUST00000235864.2
ENSMUST00000050584.10
cysteine-rich transmembrane module containing 1
chr1_+_128069677 0.16 ENSMUST00000187023.7
R3H domain containing 1
chrX_+_109857866 0.16 ENSMUST00000078229.5
POU domain, class 3, transcription factor 4
chr5_-_21906330 0.16 ENSMUST00000115217.8
ENSMUST00000060899.9
N-acyl phosphatidylethanolamine phospholipase D
chr1_+_138891155 0.15 ENSMUST00000200533.5
DENN/MADD domain containing 1B
chr13_+_37529184 0.15 ENSMUST00000021860.7
lymphocyte antigen 86
chr1_+_78286946 0.15 ENSMUST00000036172.10
sphingosine-1-phosphate phosphatase 2
chr9_-_62888156 0.15 ENSMUST00000098651.6
ENSMUST00000214830.2
protein inhibitor of activated STAT 1
chr2_+_32253692 0.15 ENSMUST00000113331.8
ENSMUST00000113338.9
CDKN1A interacting zinc finger protein 1
chr6_+_11907808 0.15 ENSMUST00000155037.4
PHD finger protein 14
chr5_-_114911509 0.15 ENSMUST00000086564.11
GIT ArfGAP 2
chr7_-_24705320 0.15 ENSMUST00000102858.10
ENSMUST00000196684.2
ENSMUST00000080882.11
ATPase, Na+/K+ transporting, alpha 3 polypeptide
chr11_+_53410697 0.14 ENSMUST00000120878.9
ENSMUST00000147912.2
septin 8
chr11_+_11636213 0.14 ENSMUST00000076700.11
ENSMUST00000048122.13
IKAROS family zinc finger 1
chr1_-_167221344 0.14 ENSMUST00000028005.3
microsomal glutathione S-transferase 3
chr4_-_120874376 0.14 ENSMUST00000043200.8
small ArfGAP 2
chr1_-_64776890 0.14 ENSMUST00000116133.4
ENSMUST00000063982.7
frizzled class receptor 5
chr8_-_41087793 0.14 ENSMUST00000173957.2
ENSMUST00000048898.17
ENSMUST00000174205.8
myotubularin related protein 7
chrX_-_47551990 0.14 ENSMUST00000033429.9
ENSMUST00000140486.2
E74-like factor 4 (ets domain transcription factor)
chr9_-_21963306 0.14 ENSMUST00000003501.9
ENSMUST00000215901.2
ELAV like RNA binding protein 3
chr2_-_160208977 0.14 ENSMUST00000099126.5
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)
chr18_-_89787603 0.13 ENSMUST00000097495.5
docking protein 6
chr11_+_76070483 0.13 ENSMUST00000129853.8
TLC domain containing 3A
chr8_+_121264161 0.13 ENSMUST00000118136.2
genetic suppressor element 1, coiled-coil protein
chr10_-_69048928 0.13 ENSMUST00000170048.2
RIKEN cDNA A930033H14 gene
chr18_+_61096660 0.13 ENSMUST00000039904.7
calcium/calmodulin-dependent protein kinase II alpha
chr8_+_3715747 0.13 ENSMUST00000014118.4
mast cell expressed membrane protein 1
chr8_+_95720864 0.13 ENSMUST00000212141.2
adhesion G protein-coupled receptor G1
chr14_-_36770898 0.13 ENSMUST00000225070.2
ENSMUST00000022338.7
retinal G protein coupled receptor
chr4_-_141325517 0.13 ENSMUST00000131317.8
ENSMUST00000006381.11
ENSMUST00000129602.8
filamin binding LIM protein 1
chr12_-_114451189 0.13 ENSMUST00000103493.3
immunoglobulin heavy variable 1-4
chr12_-_46865709 0.13 ENSMUST00000021438.8
NOVA alternative splicing regulator 1
chr6_-_52168675 0.13 ENSMUST00000101395.3
homeobox A4
chr19_+_4281953 0.13 ENSMUST00000025773.5
polymerase (DNA-directed), delta 4
chr11_-_70578744 0.13 ENSMUST00000108545.9
ENSMUST00000120261.8
calmodulin binding transcription activator 2
chr7_+_24982206 0.13 ENSMUST00000165239.3
capicua transcriptional repressor
chr7_-_140907471 0.13 ENSMUST00000211537.2
DEAF1, transcription factor
chr2_-_170248421 0.13 ENSMUST00000154650.8
breast carcinoma amplified sequence 1
chr9_+_83430363 0.13 ENSMUST00000188241.7
ENSMUST00000113215.10
SH3 domain binding glutamic acid-rich protein like 2
chr19_+_6097111 0.13 ENSMUST00000025723.9
synovial apoptosis inhibitor 1, synoviolin
chr9_+_83430395 0.12 ENSMUST00000188030.2
SH3 domain binding glutamic acid-rich protein like 2
chrX_+_84091915 0.12 ENSMUST00000239019.2
ENSMUST00000113992.3
ENSMUST00000113991.8
dystrophin, muscular dystrophy
chr7_+_44465353 0.12 ENSMUST00000208626.2
ENSMUST00000057195.17
nucleoporin 62
chr8_+_12997948 0.12 ENSMUST00000110871.8
mcf.2 transforming sequence-like
chr8_-_85500998 0.12 ENSMUST00000109762.8
nuclear factor I/X
chr4_+_42916666 0.12 ENSMUST00000132173.8
ENSMUST00000107975.8
PHD finger protein 24
chr7_-_96981221 0.12 ENSMUST00000139582.9
ubiquitin specific peptidase 35
chr15_-_76004395 0.12 ENSMUST00000239552.1
epiplakin 1
chr2_-_18397547 0.12 ENSMUST00000091418.12
ENSMUST00000166495.8
DnaJ heat shock protein family (Hsp40) member C1
chr19_+_57599452 0.12 ENSMUST00000077282.7
attractin like 1
chr5_-_25703700 0.12 ENSMUST00000173073.8
ENSMUST00000045291.14
ENSMUST00000173174.2
lysine (K)-specific methyltransferase 2C
chr15_+_61857226 0.12 ENSMUST00000161976.8
ENSMUST00000022971.8
myelocytomatosis oncogene
chr1_+_61677977 0.12 ENSMUST00000075374.10
par-3 family cell polarity regulator beta
chr14_-_19261196 0.12 ENSMUST00000112797.12
ENSMUST00000225885.2
RIKEN cDNA D830030K20 gene
chr17_+_24971952 0.12 ENSMUST00000044922.8
ENSMUST00000234202.2
heparan sulfate (glucosamine) 3-O-sulfotransferase 6
chr7_+_79675727 0.12 ENSMUST00000049680.10
zinc finger protein 710
chr11_+_101046708 0.12 ENSMUST00000043654.10
tubulin, gamma 2
chr11_+_117700479 0.12 ENSMUST00000026649.14
ENSMUST00000177131.8
ENSMUST00000120928.2
ENSMUST00000175737.2
ENSMUST00000132298.2
synaptogyrin 2
predicted gene 20708
chr14_+_26760898 0.12 ENSMUST00000035336.5
interleukin 17 receptor D
chr4_+_42917228 0.11 ENSMUST00000107976.9
ENSMUST00000069184.9
PHD finger protein 24
chr11_-_46057224 0.11 ENSMUST00000020679.3
NIPA-like domain containing 4
chr16_-_16377982 0.11 ENSMUST00000161861.8
FYVE, RhoGEF and PH domain containing 4
chr11_+_98555167 0.11 ENSMUST00000017348.3
gasdermin A
chr19_+_53128901 0.11 ENSMUST00000235754.2
ENSMUST00000237301.2
ENSMUST00000238130.2
adducin 3 (gamma)

Network of associatons between targets according to the STRING database.

First level regulatory network of Tcf3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
0.1 0.7 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.1 1.0 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 0.5 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.1 0.3 GO:2000793 negative regulation of cell proliferation involved in heart morphogenesis(GO:2000137) cell proliferation involved in heart valve development(GO:2000793)
0.1 0.4 GO:0070100 negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.1 0.3 GO:0060722 spongiotrophoblast cell proliferation(GO:0060720) cell proliferation involved in embryonic placenta development(GO:0060722)
0.1 0.6 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.1 0.3 GO:0090095 lactic acid secretion(GO:0046722) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.1 0.4 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
0.1 0.2 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.1 0.4 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.1 0.5 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 0.4 GO:1903436 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.1 0.2 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.1 0.2 GO:0071626 mastication(GO:0071626) learned vocalization behavior(GO:0098583)
0.1 0.2 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.1 0.7 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.1 0.2 GO:0002658 positive regulation of tolerance induction dependent upon immune response(GO:0002654) regulation of peripheral tolerance induction(GO:0002658) positive regulation of peripheral tolerance induction(GO:0002660) regulation of peripheral T cell tolerance induction(GO:0002849) positive regulation of peripheral T cell tolerance induction(GO:0002851)
0.1 0.2 GO:1902109 death-inducing signaling complex assembly(GO:0071550) negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.1 0.2 GO:1903999 negative regulation of eating behavior(GO:1903999)
0.1 0.7 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.3 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.1 GO:0021682 nerve maturation(GO:0021682)
0.0 0.0 GO:0090094 metanephric cap development(GO:0072185) metanephric cap morphogenesis(GO:0072186) metanephric cap mesenchymal cell proliferation involved in metanephros development(GO:0090094)
0.0 0.1 GO:0045660 positive regulation of neutrophil differentiation(GO:0045660)
0.0 0.5 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.0 0.2 GO:0035283 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.1 GO:0060715 Spemann organizer formation(GO:0060061) syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.0 0.2 GO:1903921 protein processing in phagocytic vesicle(GO:1900756) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923)
0.0 0.2 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.4 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.0 0.3 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.1 GO:0021627 olfactory nerve morphogenesis(GO:0021627) olfactory nerve structural organization(GO:0021629)
0.0 0.2 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.5 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.3 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.1 GO:0032298 positive regulation of DNA-dependent DNA replication initiation(GO:0032298)
0.0 0.1 GO:2000742 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.0 0.4 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.2 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 0.2 GO:0071899 regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.0 0.1 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 0.0 GO:0034118 erythrocyte aggregation(GO:0034117) regulation of erythrocyte aggregation(GO:0034118)
0.0 0.1 GO:2000584 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.0 0.4 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.0 0.2 GO:2001023 regulation of response to drug(GO:2001023)
0.0 0.2 GO:0048539 bone marrow development(GO:0048539)
0.0 0.2 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.1 GO:0010813 neuropeptide catabolic process(GO:0010813)
0.0 0.2 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.2 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.0 0.6 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.0 0.1 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.0 0.1 GO:0021679 cerebellar molecular layer development(GO:0021679)
0.0 0.2 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.0 0.3 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.0 GO:0051385 response to mineralocorticoid(GO:0051385)
0.0 0.3 GO:0009650 UV protection(GO:0009650)
0.0 0.1 GO:0090327 negative regulation of locomotion involved in locomotory behavior(GO:0090327)
0.0 0.1 GO:2000451 positive regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000451)
0.0 0.1 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.4 GO:2001223 negative regulation of neuron migration(GO:2001223)
0.0 0.1 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.4 GO:0042359 vitamin D metabolic process(GO:0042359)
0.0 0.1 GO:0014063 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198) negative regulation of serotonin secretion(GO:0014063)
0.0 0.2 GO:0035608 protein deglutamylation(GO:0035608)
0.0 0.7 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 0.1 GO:0048069 eye pigmentation(GO:0048069)
0.0 0.0 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.0 0.2 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.2 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.3 GO:2000194 regulation of female gonad development(GO:2000194)
0.0 0.0 GO:0006850 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.0 0.2 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.0 0.0 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.0 0.1 GO:2000405 negative regulation of T cell migration(GO:2000405)
0.0 0.1 GO:0090472 dibasic protein processing(GO:0090472)
0.0 0.6 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.1 GO:0032439 endosome localization(GO:0032439)
0.0 0.1 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.0 GO:0002017 regulation of blood volume by renal aldosterone(GO:0002017)
0.0 0.0 GO:0021571 rhombomere 5 development(GO:0021571)
0.0 0.2 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.1 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.0 0.3 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.1 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.2 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)
0.0 0.0 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.0 0.0 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.0 0.2 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.2 GO:0099628 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.0 0.2 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.0 0.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.1 GO:0030035 microspike assembly(GO:0030035)
0.0 0.2 GO:0032494 response to peptidoglycan(GO:0032494)
0.0 0.3 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.1 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.1 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.2 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.7 GO:0031648 protein destabilization(GO:0031648)
0.0 0.1 GO:0001866 NK T cell proliferation(GO:0001866)
0.0 0.2 GO:0008272 sulfate transport(GO:0008272)
0.0 0.2 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)
0.0 0.0 GO:2000556 regulation of T-helper 1 cell cytokine production(GO:2000554) positive regulation of T-helper 1 cell cytokine production(GO:2000556)
0.0 0.3 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.0 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0032997 Fc receptor complex(GO:0032997) Fc-epsilon receptor I complex(GO:0032998)
0.1 0.5 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 0.4 GO:0044316 cone cell pedicle(GO:0044316)
0.1 0.3 GO:0044307 dendritic branch(GO:0044307)
0.1 0.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.2 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.2 GO:0099573 glutamatergic postsynaptic density(GO:0099573)
0.0 0.3 GO:0033269 internode region of axon(GO:0033269)
0.0 0.4 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.4 GO:0097451 glial limiting end-foot(GO:0097451)
0.0 0.5 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.5 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.6 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.2 GO:0097255 R2TP complex(GO:0097255)
0.0 0.1 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.0 0.1 GO:0034774 secretory granule lumen(GO:0034774) cytoplasmic membrane-bounded vesicle lumen(GO:0060205)
0.0 0.2 GO:0008278 cohesin complex(GO:0008278)
0.0 0.1 GO:0036284 tubulobulbar complex(GO:0036284)
0.0 0.4 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.1 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.8 GO:0045095 keratin filament(GO:0045095)
0.0 0.4 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.1 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.3 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.8 GO:0030673 axolemma(GO:0030673)
0.0 0.3 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.0 0.7 GO:0043034 costamere(GO:0043034)
0.0 0.0 GO:0043512 inhibin A complex(GO:0043512)
0.0 0.5 GO:0016460 myosin II complex(GO:0016460)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.2 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.1 GO:0045179 apical cortex(GO:0045179)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0004995 tachykinin receptor activity(GO:0004995)
0.1 0.7 GO:0019767 IgE receptor activity(GO:0019767)
0.1 0.5 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 0.3 GO:0004096 catalase activity(GO:0004096)
0.1 0.4 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.1 0.4 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.2 GO:0045183 translation factor activity, non-nucleic acid binding(GO:0045183)
0.0 0.4 GO:0051425 PTB domain binding(GO:0051425)
0.0 1.0 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.3 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.2 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.2 GO:0035877 death effector domain binding(GO:0035877)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.5 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.3 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.5 GO:0043495 protein anchor(GO:0043495)
0.0 0.3 GO:0098821 BMP binding(GO:0036122) BMP receptor activity(GO:0098821)
0.0 0.3 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.2 GO:0033142 progesterone receptor binding(GO:0033142)
0.0 0.3 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.1 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.0 0.5 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.3 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.5 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.2 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.1 GO:0031699 beta-3 adrenergic receptor binding(GO:0031699)
0.0 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.2 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.1 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.0 0.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.9 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.1 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.0 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 0.1 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0 0.3 GO:0042166 acetylcholine binding(GO:0042166)
0.0 0.2 GO:0051378 serotonin binding(GO:0051378)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.1 GO:0050436 microfibril binding(GO:0050436)
0.0 0.2 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.2 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.0 GO:0000401 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.3 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.5 PID MYC PATHWAY C-MYC pathway
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.2 ST JAK STAT PATHWAY Jak-STAT Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.5 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.3 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.2 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.6 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.6 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.1 REACTOME OPSINS Genes involved in Opsins
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.1 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10