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avrg: GFI1 WT vs 36n/n vs KD

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Results for Tlx2

Z-value: 1.32

Motif logo

Transcription factors associated with Tlx2

Gene Symbol Gene ID Gene Info
ENSMUSG00000068327.6 T cell leukemia, homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tlx2mm39_v1_chr6_-_83047206_830473610.335.8e-01Click!

Activity profile of Tlx2 motif

Sorted Z-values of Tlx2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_24758968 0.75 ENSMUST00000154588.2
ribonucleotide reductase M2
chr7_-_126399208 0.60 ENSMUST00000133514.8
ENSMUST00000151137.8
aldolase A, fructose-bisphosphate
chr12_+_24758240 0.60 ENSMUST00000020980.12
ribonucleotide reductase M2
chr7_-_126399778 0.59 ENSMUST00000141355.4
aldolase A, fructose-bisphosphate
chr12_+_24758724 0.56 ENSMUST00000153058.8
ribonucleotide reductase M2
chr14_-_31503869 0.53 ENSMUST00000227089.2
ankyrin repeat domain 28
chr14_+_32507920 0.53 ENSMUST00000039191.8
ENSMUST00000227060.2
ENSMUST00000228481.2
transmembrane protein 273
chr3_-_96201248 0.53 ENSMUST00000029748.8
Fc receptor, IgG, high affinity I
chr3_-_98247237 0.49 ENSMUST00000065793.12
3-phosphoglycerate dehydrogenase
chr7_-_126399574 0.49 ENSMUST00000106348.8
aldolase A, fructose-bisphosphate
chr5_+_28276353 0.48 ENSMUST00000059155.11
insulin induced gene 1
chr19_+_46329552 0.48 ENSMUST00000128041.8
major facilitator superfamily domain containing 13a
chr11_-_93856783 0.47 ENSMUST00000021220.10
NME/NM23 nucleoside diphosphate kinase 1
chr14_+_46997984 0.47 ENSMUST00000067426.6
cyclin-dependent kinase inhibitor 3
chr10_+_61431271 0.46 ENSMUST00000020287.8
neuropeptide FF receptor 1
chr8_-_23680954 0.46 ENSMUST00000209507.2
glycerol-3-phosphate acyltransferase 4
chr17_-_26014613 0.46 ENSMUST00000235889.2
predicted gene, 50367
chr11_+_52265090 0.45 ENSMUST00000020673.3
voltage-dependent anion channel 1
chr15_-_8740218 0.44 ENSMUST00000005493.14
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr19_-_60862964 0.43 ENSMUST00000025961.7
peroxiredoxin 3
chr3_+_159545309 0.43 ENSMUST00000068952.10
ENSMUST00000198878.2
wntless WNT ligand secretion mediator
chrX_-_71962017 0.42 ENSMUST00000114551.10
centrin 2
chr1_+_172327812 0.41 ENSMUST00000192460.2
transgelin 2
chr11_+_101333238 0.41 ENSMUST00000107249.8
ribosomal protein L27
chr12_+_82216800 0.41 ENSMUST00000222298.2
signal-induced proliferation-associated 1 like 1
chr11_+_51654511 0.39 ENSMUST00000020653.6
secretion associated Ras related GTPase 1B
chr7_+_43000838 0.38 ENSMUST00000206299.2
ENSMUST00000121494.2
sialic acid binding Ig-like lectin F
chr6_+_85429023 0.36 ENSMUST00000204592.3
chaperonin containing Tcp1, subunit 7 (eta)
chr16_-_91728162 0.36 ENSMUST00000139277.8
ENSMUST00000154661.8
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
chr10_-_80235384 0.36 ENSMUST00000092295.10
ENSMUST00000105349.8
methyl-CpG binding domain protein 3
chr3_+_95801325 0.36 ENSMUST00000197081.2
ENSMUST00000056710.10
aph1 homolog A, gamma secretase subunit
chr7_-_30262337 0.36 ENSMUST00000207031.2
presenilin enhancer gamma secretase subunit
chr2_+_34661982 0.36 ENSMUST00000028222.13
ENSMUST00000100171.3
heat shock protein 5
chrX_+_73348832 0.36 ENSMUST00000153141.2
guanosine diphosphate (GDP) dissociation inhibitor 1
chr4_+_126156118 0.35 ENSMUST00000030660.9
trafficking protein particle complex 3
chr16_+_48692976 0.34 ENSMUST00000065666.6
resistin like gamma
chr17_+_35413415 0.34 ENSMUST00000025262.6
ENSMUST00000173600.2
lymphotoxin B
chr8_+_71047110 0.34 ENSMUST00000019283.10
ENSMUST00000210005.2
myo-inositol 1-phosphate synthase A1
chr7_-_28441173 0.34 ENSMUST00000171183.2
mitochondrial ribosomal protein S12
chr6_+_58810674 0.33 ENSMUST00000041401.11
hect domain and RLD 3
chr4_+_130253925 0.33 ENSMUST00000105994.4
small nuclear ribonucleoprotein 40 (U5)
chr11_-_51541610 0.33 ENSMUST00000142721.2
ENSMUST00000156835.8
ENSMUST00000001080.16
NEDD4 binding protein 3
chr5_-_100822097 0.32 ENSMUST00000031262.9
coenzyme Q2 4-hydroxybenzoate polyprenyltransferase
chr4_-_107928567 0.32 ENSMUST00000106701.2
sterol carrier protein 2, liver
chr7_+_46496929 0.32 ENSMUST00000132157.2
ENSMUST00000210631.2
lactate dehydrogenase A
chr9_-_71678814 0.31 ENSMUST00000122065.2
ENSMUST00000121322.8
ENSMUST00000072899.9
cingulin-like 1
chr16_-_35891739 0.31 ENSMUST00000231351.2
ENSMUST00000004057.9
family with sequence similarity 162, member A
chr18_-_61919707 0.31 ENSMUST00000120472.2
actin filament associated protein 1-like 1
chr10_+_79715448 0.31 ENSMUST00000006679.15
proteinase 3
chr6_+_50087826 0.31 ENSMUST00000167628.2
membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
chr13_+_94310500 0.31 ENSMUST00000121618.2
lipoma HMGIC fusion partner-like 2
chr3_+_32791139 0.31 ENSMUST00000127477.8
ENSMUST00000121778.8
ENSMUST00000154257.8
NADH:ubiquinone oxidoreductase subunit B5
chr7_-_141936355 0.31 ENSMUST00000133843.8
predicted gene, 49369
chr11_+_101333115 0.30 ENSMUST00000077856.13
ribosomal protein L27
chrX_+_133657312 0.30 ENSMUST00000081834.10
ENSMUST00000086880.11
ENSMUST00000086884.5
armadillo repeat containing, X-linked 3
chr18_+_60509101 0.30 ENSMUST00000032473.7
ENSMUST00000066912.13
interferon inducible GTPase 1
chr4_+_43506966 0.29 ENSMUST00000030183.10
carbonic anhydrase 9
chr9_+_107957640 0.29 ENSMUST00000162886.2
macrophage stimulating 1 (hepatocyte growth factor-like)
chr11_+_94219046 0.28 ENSMUST00000021227.6
ankyrin repeat domain 40
chr1_-_91340884 0.28 ENSMUST00000086851.2
hairy and enhancer of split 6
chr11_+_49141339 0.28 ENSMUST00000101293.11
mannoside acetylglucosaminyltransferase 1
chr2_+_84818538 0.28 ENSMUST00000028466.12
proteoglycan 3
chr7_+_43000765 0.28 ENSMUST00000012798.14
ENSMUST00000122423.8
sialic acid binding Ig-like lectin F
chr11_+_69729340 0.28 ENSMUST00000133967.8
ENSMUST00000094065.5
transmembrane protein 256
chr11_-_78642480 0.28 ENSMUST00000059468.6
cyclin Q
chr2_-_126341757 0.28 ENSMUST00000040128.12
ATPase, class I, type 8B, member 4
chr7_-_28441205 0.26 ENSMUST00000056078.9
mitochondrial ribosomal protein S12
chrX_-_71961890 0.26 ENSMUST00000152200.2
centrin 2
chr15_-_38518406 0.26 ENSMUST00000151319.8
antizyme inhibitor 1
chr7_-_16657825 0.26 ENSMUST00000019514.10
calmodulin 3
chr5_+_108048697 0.26 ENSMUST00000153590.2
ribosomal protein L5
chr7_+_127503812 0.26 ENSMUST00000151451.3
ENSMUST00000124533.3
ENSMUST00000206745.2
ENSMUST00000206140.2
branched chain ketoacid dehydrogenase kinase
chr9_+_107957621 0.26 ENSMUST00000035211.14
macrophage stimulating 1 (hepatocyte growth factor-like)
chr4_+_134123631 0.26 ENSMUST00000105869.9
platelet-activating factor acetylhydrolase 2
chr14_+_54701594 0.26 ENSMUST00000022782.10
low-density lipoprotein receptor-related protein 10
chr3_+_151143524 0.26 ENSMUST00000046977.12
adhesion G protein-coupled receptor L4
chr11_+_83328503 0.26 ENSMUST00000037378.6
RIKEN cDNA 1700020L24 gene
chr3_+_109481223 0.25 ENSMUST00000106576.3
vav 3 oncogene
chr9_-_103097022 0.25 ENSMUST00000168142.8
transferrin
chr11_+_106642052 0.25 ENSMUST00000147326.9
ENSMUST00000182896.8
ENSMUST00000182908.8
ENSMUST00000086353.11
mast cell immunoglobulin like receptor 1
chr9_+_108911547 0.25 ENSMUST00000026735.9
coiled-coil domain containing 51
chr17_+_43978377 0.25 ENSMUST00000233627.2
ENSMUST00000233437.2
cytochrome P450, family 39, subfamily a, polypeptide 1
chr5_+_45827249 0.25 ENSMUST00000117396.3
non-SMC condensin I complex, subunit G
chr11_+_94218810 0.25 ENSMUST00000107818.9
ENSMUST00000051221.13
ankyrin repeat domain 40
chr9_-_54641750 0.25 ENSMUST00000118771.8
ENSMUST00000130368.8
ENSMUST00000127451.2
ENSMUST00000051822.13
ENSMUST00000121204.8
WD repeat domain 61
chr4_+_99603877 0.24 ENSMUST00000097961.9
ENSMUST00000107004.9
ENSMUST00000139799.3
asparagine-linked glycosylation 6 (alpha-1,3,-glucosyltransferase)
chr6_+_83156550 0.24 ENSMUST00000113919.10
ENSMUST00000113918.8
ENSMUST00000141680.8
dynactin 1
chr16_+_20536415 0.24 ENSMUST00000021405.8
polymerase (RNA) II (DNA directed) polypeptide H
chr17_-_37269153 0.24 ENSMUST00000172823.2
RNA polymerase I subunit H
chr6_+_50087167 0.24 ENSMUST00000166318.8
ENSMUST00000036236.15
ENSMUST00000204545.3
ENSMUST00000036225.15
membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
chr16_-_65359406 0.24 ENSMUST00000231259.2
charged multivesicular body protein 2B
chr12_+_69771713 0.24 ENSMUST00000220916.2
ENSMUST00000021372.6
ENSMUST00000220539.2
ENSMUST00000220460.2
distal membrane arm assembly complex 2 like
chr15_-_39807081 0.24 ENSMUST00000022916.13
low density lipoprotein-related protein 12
chr3_-_88857578 0.24 ENSMUST00000174402.8
ENSMUST00000174077.8
death associated protein 3
chr8_+_18896267 0.24 ENSMUST00000149565.8
ENSMUST00000033847.5
1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)
chr6_-_72367642 0.24 ENSMUST00000059983.10
vesicle-associated membrane protein 8
chr6_+_108637577 0.24 ENSMUST00000032194.11
basic helix-loop-helix family, member e40
chr8_+_13087805 0.24 ENSMUST00000128418.8
ENSMUST00000152034.2
coagulation factor X
chr10_-_80235223 0.24 ENSMUST00000105348.8
methyl-CpG binding domain protein 3
chr11_+_49141410 0.24 ENSMUST00000129588.2
mannoside acetylglucosaminyltransferase 1
chr14_-_52341472 0.24 ENSMUST00000111610.12
ENSMUST00000164655.2
heterogeneous nuclear ribonucleoprotein C
chr11_-_100595019 0.24 ENSMUST00000017974.13
DEXH (Asp-Glu-X-His) box polypeptide 58
chr12_-_101942172 0.24 ENSMUST00000221191.2
NADH:ubiquinone oxidoreductase subunit B1
chr11_-_21522193 0.23 ENSMUST00000102874.11
ENSMUST00000238916.2
malate dehydrogenase 1, NAD (soluble)
chr11_-_21521934 0.23 ENSMUST00000239073.2
malate dehydrogenase 1, NAD (soluble)
chr3_+_103078971 0.23 ENSMUST00000005830.15
breast carcinoma amplified sequence 2
chr11_+_115310885 0.23 ENSMUST00000103035.10
potassium channel tetramerisation domain containing 2
chrX_-_149879501 0.23 ENSMUST00000112683.9
ENSMUST00000026295.10
TSR2 20S rRNA accumulation
chr7_-_30614249 0.23 ENSMUST00000190950.7
ENSMUST00000187137.7
ENSMUST00000190638.7
myelin-associated glycoprotein
chr4_-_133600308 0.23 ENSMUST00000137486.3
ribosomal protein S6 kinase polypeptide 1
chr9_+_122942280 0.23 ENSMUST00000026891.5
ENSMUST00000215377.2
exosome component 7
chr17_+_43978280 0.22 ENSMUST00000170988.2
cytochrome P450, family 39, subfamily a, polypeptide 1
chr1_-_106687457 0.22 ENSMUST00000010049.6
3-ketodihydrosphingosine reductase
chr14_+_52348396 0.22 ENSMUST00000111600.11
retinitis pigmentosa GTPase regulator interacting protein 1
chr3_+_95801263 0.22 ENSMUST00000015894.12
aph1 homolog A, gamma secretase subunit
chr7_-_45083688 0.22 ENSMUST00000210439.2
RuvB-like protein 2
chrX_-_100310959 0.22 ENSMUST00000135038.2
interleukin 2 receptor, gamma chain
chr8_+_71047010 0.22 ENSMUST00000211117.2
myo-inositol 1-phosphate synthase A1
chr8_+_73488496 0.22 ENSMUST00000058099.9
coagulation factor II (thrombin) receptor-like 3
chr5_-_123038329 0.21 ENSMUST00000031435.14
lysine (K)-specific demethylase 2B
chr16_-_55715648 0.21 ENSMUST00000099705.5
neurexophilin and PC-esterase domain family, member 3
chr6_+_40302106 0.21 ENSMUST00000031977.12
acylglycerol kinase
chr11_-_102297590 0.21 ENSMUST00000155104.8
ENSMUST00000130436.8
solute carrier family 25, member 39
chr3_-_88410495 0.21 ENSMUST00000120377.8
ENSMUST00000029699.13
lamin A
chr10_+_72490705 0.21 ENSMUST00000105431.8
ENSMUST00000160337.2
ZW10 interactor
chr2_+_30254239 0.21 ENSMUST00000077977.14
ENSMUST00000140075.9
ENSMUST00000142801.8
ENSMUST00000100214.10
mitoguardin 2
chr4_+_137977714 0.21 ENSMUST00000105824.8
ENSMUST00000124239.8
ENSMUST00000105823.2
ENSMUST00000105818.8
SH2 domain containing 5
kinesin family member 17
chr7_-_45084012 0.20 ENSMUST00000107771.12
ENSMUST00000211666.2
RuvB-like protein 2
chr5_-_23988551 0.20 ENSMUST00000148618.8
pseudouridylate synthase 7
chr16_-_65359566 0.20 ENSMUST00000004965.8
charged multivesicular body protein 2B
chr9_+_107468146 0.20 ENSMUST00000195746.2
interferon-related developmental regulator 2
chr17_+_87590308 0.20 ENSMUST00000041110.12
ENSMUST00000125875.8
tetratricopeptide repeat domain 7
chr19_+_6451667 0.20 ENSMUST00000113471.3
ENSMUST00000113469.3
RAS, guanyl releasing protein 2
chr6_-_56878854 0.20 ENSMUST00000101367.9
5'-nucleotidase, cytosolic III
chrX_-_141173330 0.20 ENSMUST00000112907.8
acyl-CoA synthetase long-chain family member 4
chr6_-_13871454 0.20 ENSMUST00000185219.2
ENSMUST00000185361.2
ENSMUST00000155856.2
RIKEN cDNA 2610001J05 gene
chrX_+_73314418 0.20 ENSMUST00000008826.14
ENSMUST00000151702.8
ENSMUST00000074085.12
ENSMUST00000135690.2
ribosomal protein L10
chr11_-_55352005 0.20 ENSMUST00000108857.2
antioxidant 1 copper chaperone
chr2_-_165129675 0.19 ENSMUST00000109299.8
ENSMUST00000109298.8
ENSMUST00000130393.2
ENSMUST00000017808.14
ENSMUST00000131409.2
ENSMUST00000156134.8
ENSMUST00000133961.8
solute carrier family 35, member C2
chr15_-_100585789 0.19 ENSMUST00000023775.9
chymotrypsin-like elastase family, member 1
chr4_-_135780660 0.19 ENSMUST00000102536.11
ribosomal protein L11
chr11_-_78875657 0.19 ENSMUST00000073001.5
lectin, galactose binding, soluble 9
chr17_+_34138699 0.19 ENSMUST00000234320.2
TAP binding protein
chr7_+_28136861 0.19 ENSMUST00000108292.9
ENSMUST00000108289.8
glia maturation factor, gamma
chr19_+_41921903 0.19 ENSMUST00000224258.2
ENSMUST00000026154.9
ENSMUST00000224896.2
zinc finger, DHHC domain containing 16
chr6_-_47790272 0.19 ENSMUST00000077290.9
protein disulfide isomerase associated 4
chr15_-_39807359 0.19 ENSMUST00000110305.3
low density lipoprotein-related protein 12
chr1_+_85992341 0.19 ENSMUST00000027432.9
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
chr11_+_68936457 0.19 ENSMUST00000108666.8
ENSMUST00000021277.6
aurora kinase B
chr13_-_20008397 0.19 ENSMUST00000222664.2
ENSMUST00000065335.3
G protein-coupled receptor 141
chr9_+_73009680 0.19 ENSMUST00000034737.13
ENSMUST00000173734.9
ENSMUST00000167514.2
ENSMUST00000174203.3
KH domain containing 3, subcortical maternal complex member
predicted gene 20509
chr16_+_91188609 0.19 ENSMUST00000160764.2
predicted gene 21970
chr17_-_25475248 0.19 ENSMUST00000182435.8
ENSMUST00000169109.3
ENSMUST00000182056.8
BAI1-associated protein 3
chr16_+_49676130 0.19 ENSMUST00000230641.2
CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
chr7_-_4815542 0.18 ENSMUST00000079496.9
ubiquitin-conjugating enzyme E2S
chr5_+_65264863 0.18 ENSMUST00000204097.3
kelch-like 5
chr4_-_130253703 0.18 ENSMUST00000134159.3
zinc finger, CCHC domain containing 17
chr9_-_96513529 0.18 ENSMUST00000034984.8
RAS p21 protein activator 2
chr5_-_23988696 0.18 ENSMUST00000119946.8
pseudouridylate synthase 7
chrX_+_74557905 0.18 ENSMUST00000114070.10
ENSMUST00000033540.6
von Hippel-Lindau binding protein 1
chr1_+_75498162 0.18 ENSMUST00000027414.16
ENSMUST00000113553.2
serine/threonine kinase 11 interacting protein
chr10_-_126956991 0.18 ENSMUST00000080975.6
ENSMUST00000164259.9
amplified in osteosarcoma
chr16_+_5051478 0.18 ENSMUST00000100196.9
ENSMUST00000049207.9
asparagine-linked glycosylation 1 (beta-1,4-mannosyltransferase)
chr7_-_117728790 0.18 ENSMUST00000206491.2
ADP-ribosylation factor-like 6 interacting protein 1
chr12_-_69771604 0.18 ENSMUST00000021370.10
L-2-hydroxyglutarate dehydrogenase
chr17_-_25459086 0.18 ENSMUST00000038973.7
ENSMUST00000115154.11
N-acetylglucosamine-1-phosphotransferase, gamma subunit
chr4_-_129271909 0.18 ENSMUST00000030610.3
zinc finger and BTB domain containing 8a
chr15_-_38518458 0.17 ENSMUST00000127848.2
antizyme inhibitor 1
chr4_-_152122891 0.17 ENSMUST00000030792.2
taste receptor, type 1, member 1
chr5_-_24650164 0.17 ENSMUST00000115043.8
ENSMUST00000115041.2
ENSMUST00000030800.13
Fas-activated serine/threonine kinase
chr17_+_25459138 0.17 ENSMUST00000063574.7
TSR3 20S rRNA accumulation
chr15_+_25774070 0.17 ENSMUST00000125667.3
myosin X
chr4_+_140428777 0.17 ENSMUST00000138808.8
ENSMUST00000038893.6
regulator of chromosome condensation 2
chr2_+_180098026 0.17 ENSMUST00000038259.13
solute carrier organic anion transporter family, member 4a1
chrX_-_163041185 0.17 ENSMUST00000112265.9
BMX non-receptor tyrosine kinase
chr4_-_63779562 0.17 ENSMUST00000030047.3
tumor necrosis factor (ligand) superfamily, member 8
chr6_+_58573656 0.17 ENSMUST00000031822.13
ATP binding cassette subfamily G member 2 (Junior blood group)
chr8_+_56393488 0.17 ENSMUST00000000275.10
glycine receptor, alpha 3 subunit
chr16_-_19525122 0.17 ENSMUST00000081880.7
lysosomal-associated membrane protein 3
chr2_-_36026785 0.17 ENSMUST00000028251.10
RNA binding motif protein 18
chr11_+_109541747 0.17 ENSMUST00000049527.7
protein kinase, cAMP dependent regulatory, type I, alpha
chr16_-_94327689 0.17 ENSMUST00000023615.7
VPS26 endosomal protein sorting factor C
chr14_+_32043944 0.16 ENSMUST00000022480.8
ENSMUST00000228529.2
oxoglutarate dehydrogenase-like
chr3_-_107667499 0.16 ENSMUST00000153114.2
ENSMUST00000118593.8
ENSMUST00000120243.8
colony stimulating factor 1 (macrophage)
chr11_+_106642079 0.16 ENSMUST00000183111.8
ENSMUST00000106794.9
mast cell immunoglobulin like receptor 1
chr4_-_129452148 0.16 ENSMUST00000167288.8
ENSMUST00000134336.3
lymphocyte protein tyrosine kinase
chr5_-_137834444 0.16 ENSMUST00000197586.2
paired immunoglobin-like type 2 receptor alpha
chr11_+_116744578 0.16 ENSMUST00000021173.14
major facilitator superfamily domain containing 11
chr2_+_60040231 0.16 ENSMUST00000102748.11
membrane associated ring-CH-type finger 7
chr17_-_45904540 0.16 ENSMUST00000163905.8
ENSMUST00000167692.8
solute carrier family 29 (nucleoside transporters), member 1
chr17_+_28059129 0.16 ENSMUST00000233657.2
U1 small nuclear ribonucleoprotein C
chr14_+_66074751 0.16 ENSMUST00000022614.7
coiled-coil domain containing 25
chr9_+_108765701 0.16 ENSMUST00000026743.14
ENSMUST00000194047.3
ubiquinol-cytochrome c reductase core protein 1
chr16_+_49675682 0.15 ENSMUST00000114496.3
CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
chr17_+_71511642 0.15 ENSMUST00000126681.8
lipin 2
chr4_+_124960465 0.15 ENSMUST00000052183.7
Smad nuclear interacting protein 1
chrX_+_71962157 0.15 ENSMUST00000033715.5
NAD(P) dependent steroid dehydrogenase-like
chr1_+_37911272 0.15 ENSMUST00000041621.5
lipoyltransferase 1
chrX_-_141173487 0.15 ENSMUST00000112904.8
ENSMUST00000112903.8
ENSMUST00000033634.5
acyl-CoA synthetase long-chain family member 4
chr1_-_139786421 0.15 ENSMUST00000194186.6
ENSMUST00000094489.5
ENSMUST00000239380.2
complement factor H-related 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Tlx2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0001788 antibody-dependent cellular cytotoxicity(GO:0001788)
0.2 0.5 GO:0006021 inositol biosynthetic process(GO:0006021)
0.2 0.5 GO:0030573 bile acid catabolic process(GO:0030573)
0.1 0.4 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.1 0.5 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.1 0.5 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
0.1 0.4 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.1 0.5 GO:0002071 glandular epithelial cell maturation(GO:0002071)
0.1 0.3 GO:0090367 negative regulation of mRNA modification(GO:0090367)
0.1 1.0 GO:0009448 gamma-aminobutyric acid metabolic process(GO:0009448)
0.1 0.3 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.1 1.7 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 0.3 GO:1903632 positive regulation of aminoacyl-tRNA ligase activity(GO:1903632)
0.1 0.3 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.1 0.3 GO:0015786 UDP-glucose transport(GO:0015786)
0.1 1.9 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.1 0.2 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160)
0.1 0.3 GO:0050822 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479) peptide stabilization(GO:0050822) peptide antigen stabilization(GO:0050823)
0.1 0.7 GO:0060763 mammary duct terminal end bud growth(GO:0060763)
0.1 0.3 GO:0032385 positive regulation of intracellular lipid transport(GO:0032379) positive regulation of intracellular sterol transport(GO:0032382) positive regulation of intracellular cholesterol transport(GO:0032385) lipid hydroperoxide transport(GO:1901373)
0.1 0.2 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.1 0.2 GO:0097052 L-kynurenine metabolic process(GO:0097052)
0.1 0.4 GO:0071899 regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.1 0.3 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.1 0.3 GO:0045575 basophil activation(GO:0045575)
0.1 0.1 GO:2000328 regulation of T-helper 17 cell lineage commitment(GO:2000328)
0.1 0.3 GO:0043321 regulation of natural killer cell degranulation(GO:0043321)
0.1 0.2 GO:0015680 intracellular copper ion transport(GO:0015680)
0.1 0.2 GO:0071846 actin filament debranching(GO:0071846)
0.1 0.2 GO:1903334 positive regulation of protein folding(GO:1903334)
0.1 0.2 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.1 0.4 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.1 0.2 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.1 0.4 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 0.2 GO:0090187 autophagosome docking(GO:0016240) pancreatic amylase secretion(GO:0036395) zymogen granule exocytosis(GO:0070625) positive regulation of pancreatic juice secretion(GO:0090187) regulation of pancreatic amylase secretion(GO:1902276)
0.1 0.2 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.1 0.6 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.1 0.3 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.1 0.2 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.1 0.2 GO:0019389 glucuronoside metabolic process(GO:0019389)
0.1 0.3 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.1 0.2 GO:0021993 initiation of neural tube closure(GO:0021993)
0.1 0.5 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.2 GO:2000435 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0 0.1 GO:0006285 base-excision repair, AP site formation(GO:0006285) nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0 0.1 GO:0070839 divalent metal ion export(GO:0070839)
0.0 0.2 GO:0032831 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831)
0.0 0.3 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.1 GO:0042128 nitrate assimilation(GO:0042128)
0.0 0.2 GO:0098971 anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.0 0.1 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.2 GO:1900245 negative regulation of MDA-5 signaling pathway(GO:0039534) positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.2 GO:0000390 spliceosomal complex disassembly(GO:0000390)
0.0 0.2 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.1 GO:2001293 fatty-acyl-CoA biosynthetic process(GO:0046949) malonyl-CoA metabolic process(GO:2001293)
0.0 0.1 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
0.0 0.2 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.5 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.1 GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 0.2 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.3 GO:0019661 glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.0 0.2 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.3 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.0 0.1 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.0 0.2 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.2 GO:0050917 sensory perception of umami taste(GO:0050917)
0.0 0.2 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.5 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.0 0.1 GO:0015855 nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855)
0.0 0.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.2 GO:0060309 elastin catabolic process(GO:0060309)
0.0 0.3 GO:0008228 opsonization(GO:0008228)
0.0 0.1 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.1 GO:0033377 protein localization to secretory granule(GO:0033366) protein localization to mast cell secretory granule(GO:0033367) protease localization to mast cell secretory granule(GO:0033368) maintenance of protein location in mast cell secretory granule(GO:0033370) T cell secretory granule organization(GO:0033371) maintenance of protease location in mast cell secretory granule(GO:0033373) protein localization to T cell secretory granule(GO:0033374) protease localization to T cell secretory granule(GO:0033375) maintenance of protein location in T cell secretory granule(GO:0033377) maintenance of protease location in T cell secretory granule(GO:0033379) granzyme B localization to T cell secretory granule(GO:0033380) maintenance of granzyme B location in T cell secretory granule(GO:0033382)
0.0 0.3 GO:0070474 positive regulation of uterine smooth muscle contraction(GO:0070474)
0.0 0.2 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.1 GO:2000320 negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.0 0.1 GO:0080163 regulation of protein serine/threonine phosphatase activity(GO:0080163)
0.0 0.4 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.0 0.1 GO:0045297 mating plug formation(GO:0042628) single-organism reproductive behavior(GO:0044704) post-mating behavior(GO:0045297)
0.0 0.1 GO:0006735 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.4 GO:1903405 protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.0 0.1 GO:0034201 response to oleic acid(GO:0034201)
0.0 0.1 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.0 0.4 GO:1901673 viral budding via host ESCRT complex(GO:0039702) regulation of mitotic spindle assembly(GO:1901673)
0.0 0.2 GO:0015862 uridine transport(GO:0015862)
0.0 0.0 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.0 0.4 GO:0033004 negative regulation of mast cell activation(GO:0033004)
0.0 0.1 GO:0070459 prolactin secretion(GO:0070459)
0.0 0.1 GO:0034436 glycoprotein transport(GO:0034436)
0.0 0.1 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.3 GO:0006071 glycerol metabolic process(GO:0006071)
0.0 0.1 GO:0070947 neutrophil mediated killing of fungus(GO:0070947)
0.0 0.8 GO:0007099 centriole replication(GO:0007099)
0.0 0.2 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.3 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.1 GO:0046606 negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.0 0.1 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.2 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 0.0 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.0 0.1 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.1 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:0006363 termination of RNA polymerase I transcription(GO:0006363) diacylglycerol catabolic process(GO:0046340)
0.0 0.2 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.2 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.4 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.2 GO:0034116 positive regulation of heterotypic cell-cell adhesion(GO:0034116)
0.0 0.2 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.1 GO:0060356 leucine import(GO:0060356)
0.0 0.1 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:2001025 positive regulation of response to drug(GO:2001025)
0.0 0.1 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.5 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 0.0 GO:0035627 ceramide transport(GO:0035627)
0.0 0.1 GO:0009597 detection of virus(GO:0009597)
0.0 0.2 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.0 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.1 GO:0046813 receptor-mediated virion attachment to host cell(GO:0046813)
0.0 0.0 GO:1904479 negative regulation of intestinal absorption(GO:1904479)
0.0 0.1 GO:0090400 stress-induced premature senescence(GO:0090400)
0.0 0.1 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.0 0.1 GO:2000303 regulation of ceramide biosynthetic process(GO:2000303)
0.0 0.2 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.1 GO:1904667 negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.0 0.0 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
0.0 0.1 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.2 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.2 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
0.0 0.1 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.3 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.1 GO:1990166 positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184) protein localization to site of double-strand break(GO:1990166)
0.0 0.0 GO:0002649 regulation of tolerance induction to self antigen(GO:0002649)
0.0 0.0 GO:1990426 homologous recombination-dependent replication fork processing(GO:1990426)
0.0 0.0 GO:0042977 regulation of activation of JAK2 kinase activity(GO:0010534) activation of JAK2 kinase activity(GO:0042977) negative regulation of activation of JAK2 kinase activity(GO:1902569)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.9 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.2 0.7 GO:0071942 XPC complex(GO:0071942)
0.1 0.2 GO:0055087 Ski complex(GO:0055087)
0.1 2.0 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 0.5 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.2 GO:0097232 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.1 0.7 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 0.5 GO:0042629 mast cell granule(GO:0042629)
0.0 0.4 GO:0097255 R2TP complex(GO:0097255)
0.0 0.7 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.2 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 0.3 GO:0042825 TAP complex(GO:0042825)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.3 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.4 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.5 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.1 GO:0032280 symmetric synapse(GO:0032280)
0.0 0.1 GO:0034455 t-UTP complex(GO:0034455)
0.0 0.2 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.1 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:0042643 actomyosin, actin portion(GO:0042643)
0.0 0.3 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.2 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 1.0 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.3 GO:0000796 condensin complex(GO:0000796)
0.0 0.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.3 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.2 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.2 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.2 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.3 GO:0097433 dense body(GO:0097433)
0.0 0.2 GO:1990075 periciliary membrane compartment(GO:1990075)
0.0 1.8 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.3 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.0 0.4 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.3 GO:0000243 commitment complex(GO:0000243)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.2 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.1 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.6 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.2 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.0 0.4 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.0 GO:1902636 kinociliary basal body(GO:1902636)
0.0 0.2 GO:0031597 proteasome regulatory particle, base subcomplex(GO:0008540) cytosolic proteasome complex(GO:0031597)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.2 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.4 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.1 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.3 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.1 GO:0045179 apical cortex(GO:0045179)
0.0 0.1 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.0 GO:0005749 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.3 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.9 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.2 0.5 GO:0016872 inositol-3-phosphate synthase activity(GO:0004512) intramolecular lyase activity(GO:0016872)
0.2 1.7 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.2 0.5 GO:0008396 oxysterol 7-alpha-hydroxylase activity(GO:0008396)
0.1 0.5 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 0.5 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.1 0.5 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.1 0.5 GO:0019770 IgG receptor activity(GO:0019770)
0.1 0.5 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.3 GO:0033814 propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121)
0.1 0.3 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.1 0.2 GO:0047312 L-phenylalanine:pyruvate aminotransferase activity(GO:0047312) glutamine-phenylpyruvate transaminase activity(GO:0047316) L-glutamine:pyruvate aminotransferase activity(GO:0047945)
0.1 0.2 GO:0001729 ceramide kinase activity(GO:0001729)
0.1 0.3 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.1 0.3 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 0.2 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.1 0.2 GO:0016979 lipoate-protein ligase activity(GO:0016979)
0.1 0.5 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.2 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 0.2 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 0.4 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.4 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0 0.3 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 0.1 GO:0036004 GAF domain binding(GO:0036004)
0.0 0.3 GO:0046978 TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.0 0.4 GO:0015288 porin activity(GO:0015288)
0.0 0.2 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.3 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.2 GO:0019976 interleukin-2 binding(GO:0019976)
0.0 0.2 GO:0032767 copper-dependent protein binding(GO:0032767)
0.0 0.3 GO:0016936 galactoside binding(GO:0016936)
0.0 0.2 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 0.5 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.3 GO:0072510 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.0 0.1 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.0 0.3 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.7 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.2 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.1 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.0 0.4 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.3 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.2 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.3 GO:0043426 MRF binding(GO:0043426)
0.0 0.3 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.2 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.0 0.1 GO:0098809 nitrite reductase activity(GO:0098809)
0.0 0.2 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.3 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.1 GO:0005350 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205) glycerol channel activity(GO:0015254)
0.0 0.2 GO:0034452 dynactin binding(GO:0034452)
0.0 0.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.2 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.5 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.2 GO:0046527 glucosyltransferase activity(GO:0046527)
0.0 0.2 GO:0001055 RNA polymerase I activity(GO:0001054) RNA polymerase II activity(GO:0001055)
0.0 0.1 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.2 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.3 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.3 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.2 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.0 0.2 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.0 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.0 0.0 GO:0038052 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.3 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 0.1 GO:0097001 ceramide binding(GO:0097001)
0.0 0.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.4 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.0 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.0 GO:0001571 non-tyrosine kinase fibroblast growth factor receptor activity(GO:0001571)
0.0 0.1 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.1 GO:0051373 FATZ binding(GO:0051373)
0.0 0.2 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.1 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.3 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.2 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.2 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.2 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 0.0 GO:0098782 mechanically-gated potassium channel activity(GO:0098782)
0.0 0.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.4 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.2 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.1 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 2.1 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.4 PID MYC PATHWAY C-MYC pathway
0.0 0.5 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.7 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.5 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 1.4 PID E2F PATHWAY E2F transcription factor network
0.0 0.2 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.5 PID AURORA B PATHWAY Aurora B signaling
0.0 0.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.5 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 2.2 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.7 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.3 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.3 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.4 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.2 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.8 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.4 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.5 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 1.6 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.4 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.1 REACTOME ION CHANNEL TRANSPORT Genes involved in Ion channel transport
0.0 0.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.4 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.1 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.7 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.1 REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.0 0.2 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere