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avrg: GFI1 WT vs 36n/n vs KD

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Results for Xbp1_Creb3l1

Z-value: 1.75

Motif logo

Transcription factors associated with Xbp1_Creb3l1

Gene Symbol Gene ID Gene Info
ENSMUSG00000020484.20 X-box binding protein 1
ENSMUSG00000027230.10 cAMP responsive element binding protein 3-like 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Creb3l1mm39_v1_chr2_-_91854844_918548470.355.6e-01Click!
Xbp1mm39_v1_chr11_+_5470652_54706590.237.1e-01Click!

Activity profile of Xbp1_Creb3l1 motif

Sorted Z-values of Xbp1_Creb3l1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_72935382 2.13 ENSMUST00000144337.2
thymosin, beta 10
chr3_+_123061094 1.35 ENSMUST00000047923.12
ENSMUST00000200333.2
Sec24 related gene family, member D (S. cerevisiae)
chr15_+_31224555 1.17 ENSMUST00000186109.2
death-associated protein
chr6_-_72935468 1.06 ENSMUST00000114050.8
thymosin, beta 10
chr6_-_72935171 0.96 ENSMUST00000114049.2
thymosin, beta 10
chr15_+_31224616 0.95 ENSMUST00000186547.7
death-associated protein
chr14_+_26359191 0.91 ENSMUST00000022429.9
ADP-ribosylation factor 4
chr14_+_26359390 0.88 ENSMUST00000112318.10
ADP-ribosylation factor 4
chr3_-_131196213 0.83 ENSMUST00000197057.2
sphingomyelin synthase 2
chr2_+_80145805 0.82 ENSMUST00000028392.8
DnaJ heat shock protein family (Hsp40) member C10
chr15_+_31224460 0.76 ENSMUST00000044524.16
death-associated protein
chr2_+_70491901 0.74 ENSMUST00000112201.8
ENSMUST00000028509.11
ENSMUST00000133432.8
ENSMUST00000112205.2
golgi reassembly stacking protein 2
chr8_+_26210064 0.70 ENSMUST00000068916.16
ENSMUST00000139836.8
phospholipid phosphatase 5
chr10_+_128744689 0.66 ENSMUST00000105229.9
CD63 antigen
chr19_+_32573182 0.65 ENSMUST00000235594.2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr6_-_52181393 0.64 ENSMUST00000048794.7
homeobox A5
chr9_-_89586960 0.56 ENSMUST00000058488.9
transmembrane p24 trafficking protein 3
chr10_-_18619439 0.48 ENSMUST00000019999.7
ARFGEF family member 3
chr5_-_148989821 0.48 ENSMUST00000139443.8
ENSMUST00000085546.13
high mobility group box 1
chr9_+_86454018 0.47 ENSMUST00000185566.7
ENSMUST00000034988.10
ENSMUST00000179212.3
RWD domain containing 2A
chr18_+_57487908 0.45 ENSMUST00000238069.2
proline-rich coiled-coil 1
chr2_+_164339438 0.42 ENSMUST00000103101.11
ENSMUST00000117066.8
phosphatidylinositol glycan anchor biosynthesis, class T
chr13_-_38712387 0.39 ENSMUST00000035988.16
thioredoxin domain containing 5
chr19_-_5821442 0.39 ENSMUST00000236978.2
SCY1-like 1 (S. cerevisiae)
chr3_-_27764571 0.38 ENSMUST00000046157.10
fibronectin type III domain containing 3B
chr7_+_116103599 0.38 ENSMUST00000032895.15
nucleobindin 2
chr7_+_116103643 0.37 ENSMUST00000183175.8
nucleobindin 2
chr10_-_84369831 0.36 ENSMUST00000167671.2
ENSMUST00000053871.5
cytoskeleton-associated protein 4
chr6_+_29348068 0.35 ENSMUST00000173216.8
ENSMUST00000173694.5
ENSMUST00000172974.8
ENSMUST00000031779.17
ENSMUST00000090481.14
calumenin
chr10_-_18619658 0.35 ENSMUST00000215836.2
ARFGEF family member 3
chr19_-_5821373 0.32 ENSMUST00000236297.2
ENSMUST00000236773.2
ENSMUST00000025890.10
SCY1-like 1 (S. cerevisiae)
chr4_+_47474652 0.32 ENSMUST00000065678.6
Sec61 beta subunit
chr1_-_13660027 0.30 ENSMUST00000027068.11
translocating chain-associating membrane protein 1
chr1_+_157334347 0.30 ENSMUST00000027881.15
SEC16 homolog B (S. cerevisiae)
chr1_+_157334298 0.30 ENSMUST00000086130.9
SEC16 homolog B (S. cerevisiae)
chr12_-_69230760 0.29 ENSMUST00000110620.2
ENSMUST00000110619.2
ENSMUST00000054544.7
ribosomal protein L36A-like
chr7_+_26958150 0.28 ENSMUST00000079258.7
numb-like
chr8_+_70755168 0.27 ENSMUST00000066469.14
coatomer protein complex, subunit epsilon
chr4_+_47474715 0.27 ENSMUST00000137461.8
ENSMUST00000125622.2
Sec61 beta subunit
chr1_-_183150867 0.26 ENSMUST00000194543.4
melanoma inhibitory activity 3
chr19_-_6134703 0.26 ENSMUST00000161548.8
zinc finger like protein 1
chr4_+_33031342 0.26 ENSMUST00000124992.8
ubiquitin-conjugating enzyme E2J 1
chr11_+_3464861 0.25 ENSMUST00000094469.6
selenoprotein M
chr17_+_34341766 0.24 ENSMUST00000042121.11
histocompatibility 2, class II, locus DMa
chr10_+_128745214 0.23 ENSMUST00000220308.2
CD63 antigen
chr16_-_35311243 0.23 ENSMUST00000023550.9
protein disulfide isomerase associated 5
chr17_-_34250474 0.21 ENSMUST00000171872.3
ENSMUST00000025186.16
solute carrier family 39 (zinc transporter), member 7
chr7_+_128125339 0.21 ENSMUST00000033136.9
BCL2-associated athanogene 3
chrX_+_72830668 0.20 ENSMUST00000002090.3
signal sequence receptor, delta
chr19_-_6886965 0.20 ENSMUST00000173091.2
peroxiredoxin 5
chr6_-_88495835 0.19 ENSMUST00000032168.7
Sec61 alpha 1 subunit (S. cerevisiae)
chr1_-_171910324 0.19 ENSMUST00000003550.11
nicastrin
chr19_+_46750016 0.18 ENSMUST00000099373.12
ENSMUST00000077666.6
cyclin M2
chr9_-_21003268 0.18 ENSMUST00000115487.3
ribonucleoprotein, PTB-binding 1
chrX_+_72830607 0.17 ENSMUST00000166518.8
signal sequence receptor, delta
chr7_-_44741622 0.17 ENSMUST00000210469.2
ENSMUST00000211352.2
ENSMUST00000019683.11
reticulocalbin 3, EF-hand calcium binding domain
chr10_-_67120959 0.16 ENSMUST00000159002.2
ENSMUST00000077839.13
nuclear receptor binding factor 2
chr11_-_86698484 0.16 ENSMUST00000018569.14
DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr6_-_4086914 0.16 ENSMUST00000049166.5
Bet1 golgi vesicular membrane trafficking protein
chr7_+_79910948 0.16 ENSMUST00000117989.2
neugrin, neurite outgrowth associated
chr17_-_56490887 0.16 ENSMUST00000019723.8
myeloid derived growth factor
chr15_-_57755753 0.15 ENSMUST00000022993.7
Der1-like domain family, member 1
chr7_+_49559859 0.15 ENSMUST00000056442.12
solute carrier family 6 (neurotransmitter transporter, glycine), member 5
chr3_+_89153704 0.15 ENSMUST00000168900.3
keratinocyte associated protein 2
chr11_+_53991750 0.15 ENSMUST00000093107.12
ENSMUST00000019050.12
ENSMUST00000174616.8
ENSMUST00000129499.8
ENSMUST00000126840.8
procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide
chr6_+_88061464 0.15 ENSMUST00000032143.8
ribophorin I
chr5_+_113873864 0.15 ENSMUST00000065698.7
FIC domain containing
chrX_-_72830487 0.15 ENSMUST00000052761.9
isocitrate dehydrogenase 3 (NAD+), gamma
chr13_-_76246689 0.14 ENSMUST00000239063.2
ENSMUST00000120573.3
arylsulfatase K
chr19_+_32734884 0.14 ENSMUST00000013807.8
phosphatase and tensin homolog
chr10_+_41395410 0.14 ENSMUST00000019962.15
CD164 antigen
chr15_+_79575046 0.14 ENSMUST00000046463.10
GTP binding protein 1
chr11_-_20781009 0.14 ENSMUST00000047028.9
lectin, galactoside binding-like
chr3_+_144276448 0.13 ENSMUST00000106211.3
selenoprotein F
chr9_+_108216466 0.13 ENSMUST00000193987.2
glutathione peroxidase 1
chr12_+_59177552 0.13 ENSMUST00000175877.8
MIA SH3 domain ER export factor 2
chr12_+_51424343 0.13 ENSMUST00000219434.2
ENSMUST00000021335.7
Sec1 family domain containing 1
chr1_-_10038030 0.12 ENSMUST00000185184.2
transcription factor 24
chr7_+_138792890 0.12 ENSMUST00000016124.15
leucine rich repeat containing 27
chr19_+_6887059 0.12 ENSMUST00000088257.14
ENSMUST00000116551.10
tRNA methyltransferase 11-2
chr11_-_93776580 0.12 ENSMUST00000066888.10
UTP18 small subunit processome component
chr17_-_26004298 0.11 ENSMUST00000150324.8
hydroxyacylglutathione hydrolase-like
chr3_+_144276154 0.11 ENSMUST00000082437.11
selenoprotein F
chr19_-_6886898 0.11 ENSMUST00000238095.2
peroxiredoxin 5
chr19_+_5138562 0.11 ENSMUST00000238093.2
ENSMUST00000025811.6
ENSMUST00000237025.2
Yip1 interacting factor homolog A (S. cerevisiae)
chr5_+_77122530 0.10 ENSMUST00000101087.10
ENSMUST00000120550.2
signal recognition particle 72
chr18_+_34464185 0.10 ENSMUST00000072576.10
ENSMUST00000119329.8
signal recognition particle 19
chr7_+_45434755 0.10 ENSMUST00000233503.2
ENSMUST00000120005.10
ENSMUST00000211609.2
lemur tyrosine kinase 3
chr8_-_70755132 0.10 ENSMUST00000008004.10
DEAD box helicase 49
chr6_-_29212295 0.10 ENSMUST00000078155.12
inosine monophosphate dehydrogenase 1
chr4_-_57300361 0.10 ENSMUST00000153926.8
protein tyrosine phosphatase, non-receptor type 3
chr3_-_84489923 0.10 ENSMUST00000143514.3
ADP-ribosylation factor interacting protein 1
chr5_+_65127412 0.09 ENSMUST00000031080.15
family with sequence similarity 114, member A1
chr17_-_34250616 0.09 ENSMUST00000169397.9
solute carrier family 39 (zinc transporter), member 7
chr4_+_154041687 0.09 ENSMUST00000105645.9
ENSMUST00000058393.9
ENSMUST00000141493.8
RIKEN cDNA A430005L14 gene
chr10_-_84938350 0.09 ENSMUST00000059383.8
ENSMUST00000216889.2
four and a half LIM domains 4
chr19_-_5345423 0.09 ENSMUST00000235182.2
ENSMUST00000025774.11
splicing factor 3b, subunit 2
chr9_-_107109108 0.09 ENSMUST00000044532.11
dedicator of cyto-kinesis 3
chr19_+_6326755 0.09 ENSMUST00000025684.4
EH-domain containing 1
chr4_+_148675939 0.09 ENSMUST00000006611.9
spermidine synthase
chr17_-_83821716 0.09 ENSMUST00000025095.9
ENSMUST00000167741.9
cytochrome c oxidase subunit 7A2 like
chr10_-_83173708 0.08 ENSMUST00000039956.6
solute carrier family 41, member 2
chr4_-_151946124 0.08 ENSMUST00000169423.9
calmodulin binding transcription activator 1
chr10_+_41395870 0.08 ENSMUST00000189300.2
CD164 antigen
chr9_+_108216433 0.08 ENSMUST00000191997.2
glutathione peroxidase 1
chr4_-_43562397 0.08 ENSMUST00000030187.14
talin 1
chr2_-_58247764 0.08 ENSMUST00000112608.9
ENSMUST00000112607.3
ENSMUST00000028178.14
activin A receptor, type IC
chr9_+_55056648 0.07 ENSMUST00000121677.8
ubiquitin-conjugating enzyme E2Q family member 2
chr2_-_168072493 0.07 ENSMUST00000109193.8
dolichol-phosphate (beta-D) mannosyltransferase 1
chr9_+_44290787 0.07 ENSMUST00000066601.13
hypoxia up-regulated 1
chr17_+_53786240 0.07 ENSMUST00000017975.7
RAB5A, member RAS oncogene family
chr10_-_121933276 0.07 ENSMUST00000140299.3
ribitol xylosyltransferase 1
chr6_-_102550062 0.07 ENSMUST00000203619.3
contactin 3
chr18_+_52464577 0.07 ENSMUST00000025388.7
ferritin mitochondrial
chr17_-_34340918 0.07 ENSMUST00000151986.2
bromodomain containing 2
chr11_+_62139782 0.07 ENSMUST00000018644.3
adenosine A2b receptor
chr7_-_16657825 0.07 ENSMUST00000019514.10
calmodulin 3
chr11_+_94520567 0.07 ENSMUST00000021239.7
leucine rich repeat containing 59
chr7_-_126986331 0.07 ENSMUST00000049052.4
RIKEN cDNA 9130019O22 gene
chr1_-_75455915 0.06 ENSMUST00000079205.14
ENSMUST00000094818.4
chondroitin polymerizing factor
chr7_+_44813363 0.06 ENSMUST00000085374.7
ENSMUST00000209634.2
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
chr5_+_143389573 0.06 ENSMUST00000110731.4
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr7_-_44861235 0.06 ENSMUST00000210741.2
ENSMUST00000209466.2
dickkopf-like 1
chr5_-_72716942 0.06 ENSMUST00000074948.5
ENSMUST00000087216.12
nuclear transcription factor, X-box binding-like 1
chr9_+_57468217 0.06 ENSMUST00000045791.11
ENSMUST00000216986.2
secretory carrier membrane protein 2
chr6_-_29212239 0.06 ENSMUST00000160878.8
inosine monophosphate dehydrogenase 1
chr8_-_106692668 0.06 ENSMUST00000116429.9
ENSMUST00000034370.17
solute carrier family 12, member 4
chr1_+_75456173 0.06 ENSMUST00000113575.9
ENSMUST00000148980.2
ENSMUST00000050899.7
ENSMUST00000187411.2
transmembrane protein 198
chr13_-_55469735 0.06 ENSMUST00000035242.9
RAB24, member RAS oncogene family
chr4_+_109835224 0.06 ENSMUST00000061187.4
doublesex and mab-3 related transcription factor like family A2
chr2_-_143853122 0.05 ENSMUST00000016072.12
ENSMUST00000037875.6
ribosome binding protein 1
chr7_-_121666486 0.05 ENSMUST00000033159.4
glutamyl-tRNA synthetase 2, mitochondrial
chr4_-_151946219 0.05 ENSMUST00000097774.9
calmodulin binding transcription activator 1
chr6_-_54570124 0.05 ENSMUST00000046520.13
FK506 binding protein 14
chr5_+_31026967 0.05 ENSMUST00000114716.4
transmembrane protein 214
chr4_-_155737841 0.05 ENSMUST00000030937.2
matrix metallopeptidase 23
chr7_-_44741138 0.05 ENSMUST00000210527.2
reticulocalbin 3, EF-hand calcium binding domain
chr4_+_43578922 0.05 ENSMUST00000030190.9
RAB6A GEF compex partner 1
chr3_-_19682833 0.05 ENSMUST00000119133.2
RIKEN cDNA 1700064H15 gene
chr10_+_42637479 0.05 ENSMUST00000019937.5
SEC63-like (S. cerevisiae)
chr16_+_51851917 0.05 ENSMUST00000227062.2
Casitas B-lineage lymphoma b
chr11_-_68743944 0.05 ENSMUST00000018880.14
nudE neurodevelopment protein 1 like 1
chr11_-_72686627 0.05 ENSMUST00000079681.6
cytochrome b5 domain containing 2
chr2_-_168584020 0.05 ENSMUST00000109177.8
ATPase, class II, type 9A
chr16_+_51851948 0.05 ENSMUST00000226593.2
Casitas B-lineage lymphoma b
chr4_+_150939521 0.05 ENSMUST00000030811.2
ERBB receptor feedback inhibitor 1
chr2_+_153716958 0.04 ENSMUST00000028983.3
BPI fold containing family B, member 2
chr1_-_71454041 0.04 ENSMUST00000087268.7
ATP-binding cassette, sub-family A (ABC1), member 12
chr7_+_138792919 0.04 ENSMUST00000156768.8
leucine rich repeat containing 27
chr11_-_96807273 0.04 ENSMUST00000103152.11
CDK5 regulatory subunit associated protein 3
chr3_-_27764522 0.03 ENSMUST00000195008.6
fibronectin type III domain containing 3B
chr16_+_17716480 0.03 ENSMUST00000055374.8
testis-specific serine kinase 2
chr8_+_71819854 0.03 ENSMUST00000019169.8
unconventional SNARE in the ER 1 homolog (S. cerevisiae)
chr1_-_3741721 0.03 ENSMUST00000070533.5
X-linked Kx blood group related 4
chr14_-_60324265 0.03 ENSMUST00000080368.13
ATPase, aminophospholipid transporter-like, class I, type 8A, member 2
chr9_+_7571397 0.03 ENSMUST00000120900.8
ENSMUST00000151853.8
ENSMUST00000152878.3
matrix metallopeptidase 27
chr9_+_44290832 0.03 ENSMUST00000161318.8
ENSMUST00000217019.2
ENSMUST00000160902.8
hypoxia up-regulated 1
chr14_+_63673843 0.03 ENSMUST00000121288.2
family with sequence similarity 167, member A
chr15_-_48655329 0.03 ENSMUST00000160658.8
ENSMUST00000100670.10
ENSMUST00000162830.8
CUB and Sushi multiple domains 3
chr8_-_46747629 0.03 ENSMUST00000058636.9
helt bHLH transcription factor
chr7_-_127048165 0.03 ENSMUST00000106299.2
zinc finger protein 689
chr8_+_71819534 0.03 ENSMUST00000110054.8
ENSMUST00000139541.8
unconventional SNARE in the ER 1 homolog (S. cerevisiae)
chr9_+_8900460 0.03 ENSMUST00000070463.10
ENSMUST00000098986.4
progesterone receptor
chr4_-_108263873 0.02 ENSMUST00000184609.2
glutathione peroxidase 7
chr5_-_97540230 0.02 ENSMUST00000060265.6
N(alpha)-acetyltransferase 11, NatA catalytic subunit
chr12_+_88920169 0.02 ENSMUST00000057634.14
neurexin III
chr14_-_21798678 0.02 ENSMUST00000075040.9
dual specificity phosphatase 13
chr19_+_3758285 0.02 ENSMUST00000237320.2
ENSMUST00000039048.2
ENSMUST00000235295.2
ENSMUST00000237955.2
ENSMUST00000235837.2
RIKEN cDNA 1810055G02 gene
chr9_-_103079312 0.02 ENSMUST00000035157.10
signal recognition particle receptor, B subunit
chr11_+_53992054 0.02 ENSMUST00000135653.8
procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide
chr4_+_33031433 0.02 ENSMUST00000029944.13
ubiquitin-conjugating enzyme E2J 1
chr7_-_126975199 0.02 ENSMUST00000067425.6
zinc finger protein 747
chr12_-_4088905 0.02 ENSMUST00000111178.2
EFR3 homolog B
chr16_+_51851588 0.02 ENSMUST00000114471.3
Casitas B-lineage lymphoma b
chr19_+_8718777 0.02 ENSMUST00000176381.8
syntaxin 5A
chr7_-_81642034 0.02 ENSMUST00000026096.10
basonuclin 1
chr10_-_128236366 0.02 ENSMUST00000219131.2
solute carrier family 39 (metal ion transporter), member 5
chr6_-_126717590 0.02 ENSMUST00000185333.2
potassium voltage-gated channel, shaker-related, subfamily, member 6
chr18_+_51250748 0.01 ENSMUST00000116639.4
proline rich 16
chr4_-_137523659 0.01 ENSMUST00000030551.11
alkaline phosphatase, liver/bone/kidney
chr2_-_6327884 0.01 ENSMUST00000238876.2
RIKEN cDNA 1700014B07 gene
chr10_-_128236317 0.01 ENSMUST00000167859.2
ENSMUST00000218858.2
solute carrier family 39 (metal ion transporter), member 5
chr8_+_126722113 0.01 ENSMUST00000212831.2
potassium channel, subfamily K, member 1
chr15_+_23036535 0.01 ENSMUST00000164787.8
cadherin 18
chr7_+_6392535 0.01 ENSMUST00000207465.2
ENSMUST00000208338.2
zinc finger protein 28
chr4_-_151946155 0.01 ENSMUST00000049790.14
calmodulin binding transcription activator 1
chr11_+_78079631 0.01 ENSMUST00000056241.12
ENSMUST00000207728.2
RAB34, member RAS oncogene family
chr6_-_126717114 0.01 ENSMUST00000112242.2
potassium voltage-gated channel, shaker-related, subfamily, member 6
chr16_-_32698091 0.01 ENSMUST00000119810.2
RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein
chr19_+_8875459 0.01 ENSMUST00000096246.5
ENSMUST00000235274.2
alpha glucosidase 2 alpha neutral subunit
chr2_+_32460868 0.01 ENSMUST00000140592.8
ENSMUST00000028151.7
dolichol-phosphate (beta-D) mannosyltransferase 2
chr8_+_126721878 0.01 ENSMUST00000046765.10
potassium channel, subfamily K, member 1
chr3_-_107993906 0.01 ENSMUST00000102638.8
ENSMUST00000102637.8
adenosine monophosphate deaminase 2
chr8_-_106863423 0.01 ENSMUST00000146940.2
epithelial splicing regulatory protein 2
chr11_+_85777185 0.01 ENSMUST00000108047.8
T-box 4
chr14_-_55163311 0.01 ENSMUST00000022813.8
embryonal Fyn-associated substrate
chr7_-_126986285 0.01 ENSMUST00000164345.2
RIKEN cDNA 9130019O22 gene
chr5_-_35836761 0.01 ENSMUST00000114233.3
HtrA serine peptidase 3
chr10_-_78588884 0.01 ENSMUST00000105383.4
coiled-coil domain containing 105
chr5_-_135280063 0.01 ENSMUST00000062572.3
frizzled class receptor 9

Network of associatons between targets according to the STRING database.

First level regulatory network of Xbp1_Creb3l1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:2000845 positive regulation of testosterone secretion(GO:2000845)
0.2 0.6 GO:0060435 bronchiole development(GO:0060435) intestinal epithelial cell maturation(GO:0060574)
0.2 1.8 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.2 0.6 GO:0034036 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.2 0.5 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270)
0.2 0.6 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.1 0.9 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.1 0.8 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 0.5 GO:0010269 response to selenium ion(GO:0010269)
0.1 0.8 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 0.2 GO:0002396 MHC protein complex assembly(GO:0002396) peptide antigen assembly with MHC protein complex(GO:0002501)
0.1 0.3 GO:0060785 regulation of apoptosis involved in tissue homeostasis(GO:0060785)
0.1 1.4 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 0.6 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.1 0.4 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.2 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.1 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 2.9 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.0 0.1 GO:0070476 rRNA (guanine-N7)-methylation(GO:0070476)
0.0 0.2 GO:0036233 glycine import(GO:0036233)
0.0 0.2 GO:0039019 pronephric nephron development(GO:0039019)
0.0 0.3 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.1 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.4 GO:0060510 Type II pneumocyte differentiation(GO:0060510)
0.0 0.1 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.0 0.2 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.8 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0002880 chronic inflammatory response to non-antigenic stimulus(GO:0002545) regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002880)
0.0 0.1 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.0 0.3 GO:0021873 forebrain neuroblast division(GO:0021873)
0.0 0.2 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.1 GO:1903297 regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.2 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.1 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.2 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.0 GO:0035627 ceramide transport(GO:0035627)
0.0 0.7 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.3 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.1 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.1 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.1 GO:0061727 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.5 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.2 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0031904 endosome lumen(GO:0031904)
0.1 1.0 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1 1.4 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 1.1 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 0.9 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.4 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 0.2 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 1.5 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0 0.2 GO:0097413 Lewy body(GO:0097413)
0.0 0.2 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.1 GO:0098842 postsynaptic early endosome(GO:0098842)
0.0 0.1 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.4 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.9 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.1 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.9 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 1.8 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.3 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.0 GO:0097209 epidermal lamellar body(GO:0097209)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0004020 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.2 0.5 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.1 0.8 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 2.9 GO:0070513 death domain binding(GO:0070513)
0.1 0.6 GO:0048408 epidermal growth factor binding(GO:0048408)
0.1 0.3 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.1 4.2 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.3 GO:0072541 peroxynitrite reductase activity(GO:0072541)
0.1 0.4 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.8 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.1 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 1.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.3 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.5 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.2 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.0 0.7 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.2 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.1 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.8 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0038100 nodal binding(GO:0038100)
0.0 0.1 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.0 0.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.1 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021)
0.0 0.0 GO:0034191 apolipoprotein A-I receptor binding(GO:0034191)
0.0 0.1 GO:0015321 sodium:inorganic phosphate symporter activity(GO:0015319) sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.2 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.1 GO:0030911 TPR domain binding(GO:0030911)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.5 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.1 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.8 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.1 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.5 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.4 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.2 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR