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avrg: GFI1 WT vs 36n/n vs KD

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Results for Zbtb12

Z-value: 1.18

Motif logo

Transcription factors associated with Zbtb12

Gene Symbol Gene ID Gene Info
ENSMUSG00000049823.10 zinc finger and BTB domain containing 12

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zbtb12mm39_v1_chr17_+_35113490_35113554-0.563.3e-01Click!

Activity profile of Zbtb12 motif

Sorted Z-values of Zbtb12 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_129854256 1.09 ENSMUST00000110299.3
transglutaminase 3, E polypeptide
chrX_+_93768175 0.83 ENSMUST00000101388.4
zinc finger, X-linked, duplicated B
chr3_-_131138541 0.76 ENSMUST00000090246.5
ENSMUST00000126569.2
sphingomyelin synthase 2
chr11_-_98436626 0.60 ENSMUST00000103141.4
IKAROS family zinc finger 3
chr7_-_25239229 0.59 ENSMUST00000044547.10
ENSMUST00000066503.14
ENSMUST00000064862.13
carcinoembryonic antigen-related cell adhesion molecule 2
chr7_+_99825886 0.54 ENSMUST00000178946.9
potassium voltage-gated channel, Isk-related subfamily, gene 3
chr13_-_22219738 0.54 ENSMUST00000091742.6
H2A clustered histone 12
chr7_-_25176959 0.52 ENSMUST00000098668.3
ENSMUST00000206687.2
ENSMUST00000206676.2
ENSMUST00000205308.2
ENSMUST00000098669.8
ENSMUST00000206171.2
ENSMUST00000098666.9
carcinoembryonic antigen-related cell adhesion molecule 1
chr11_+_54793569 0.44 ENSMUST00000082430.11
glutathione peroxidase 3
chr13_+_9326513 0.39 ENSMUST00000174552.8
disco interacting protein 2 homolog C
chr9_+_38407097 0.37 ENSMUST00000214003.3
ENSMUST00000214264.3
olfactory receptor 907
chr17_+_48606948 0.33 ENSMUST00000233092.2
triggering receptor expressed on myeloid cells-like 2
chr14_-_79718890 0.27 ENSMUST00000022601.7
WW domain binding protein 4
chr7_-_126574959 0.25 ENSMUST00000206296.2
ENSMUST00000205437.3
CDIP transferase, opposite strand
chr11_+_69881885 0.24 ENSMUST00000018711.15
gamma-aminobutyric acid receptor associated protein
chr8_-_43981143 0.22 ENSMUST00000080135.5
a disintegrin and metallopeptidase domain 26B
chr6_-_24528012 0.22 ENSMUST00000023851.9
NADH:ubiquinone oxidoreductase subunit A5
chr4_-_41723129 0.20 ENSMUST00000171641.2
ENSMUST00000030158.11
dynactin 3
chr15_-_82238432 0.20 ENSMUST00000230494.2
ENSMUST00000023085.7
NADH:ubiquinone oxidoreductase subunit A6
chr5_-_142515792 0.20 ENSMUST00000099400.3
poly (A) polymerase beta (testis specific)
chr14_+_54380308 0.17 ENSMUST00000196323.2
T cell receptor delta, constant region
chr16_-_19703014 0.16 ENSMUST00000100083.5
ENSMUST00000231564.2
RIKEN cDNA A930003A15 gene
chr9_-_62895197 0.16 ENSMUST00000216209.2
protein inhibitor of activated STAT 1
chr16_-_20121108 0.15 ENSMUST00000048642.15
ENSMUST00000232036.2
presenilin associated, rhomboid-like
chr5_+_96989853 0.15 ENSMUST00000196126.2
annexin A3
chr10_-_5144699 0.15 ENSMUST00000215467.2
spectrin repeat containing, nuclear envelope 1
chr10_+_75152705 0.15 ENSMUST00000105420.3
adenosine A2a receptor
chr16_+_55786638 0.15 ENSMUST00000023269.5
ribosomal protein L24
chr11_-_70590923 0.14 ENSMUST00000108543.4
ENSMUST00000108542.8
ENSMUST00000108541.9
ENSMUST00000126114.9
ENSMUST00000073625.8
inhibitor of CDK, cyclin A1 interacting protein 1
chr7_+_35285657 0.13 ENSMUST00000040844.16
ENSMUST00000188906.7
ENSMUST00000186245.7
ENSMUST00000190503.7
ankyrin repeat domain 27 (VPS9 domain)
chr4_+_43669266 0.13 ENSMUST00000107864.8
transmembrane protein 8B
chr9_+_123902143 0.12 ENSMUST00000168841.3
ENSMUST00000055918.7
chemokine (C-C motif) receptor 2
chr11_+_54793743 0.11 ENSMUST00000149324.3
glutathione peroxidase 3
chr7_+_126575510 0.11 ENSMUST00000206780.2
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)
chr19_-_46561532 0.11 ENSMUST00000026009.10
ENSMUST00000236255.2
ADP-ribosylation factor-like 3
chr14_+_26414422 0.11 ENSMUST00000022433.12
dynein, axonemal, heavy chain 12
chr13_-_14787602 0.10 ENSMUST00000220621.2
mitochondrial ribosomal protein L32
chr19_+_6130059 0.10 ENSMUST00000149347.8
ENSMUST00000143303.2
transmembrane protein 262
chr8_-_70411054 0.10 ENSMUST00000211960.2
GATA zinc finger domain containing 2A
chr18_+_36877709 0.10 ENSMUST00000007042.6
ENSMUST00000237095.2
IK cytokine
chr11_-_118021460 0.10 ENSMUST00000132685.9
dynein, axonemal, heavy chain 17
chr19_+_6919691 0.09 ENSMUST00000113426.8
ENSMUST00000238184.2
ENSMUST00000113423.10
ENSMUST00000237334.2
ENSMUST00000235240.2
BCL2-associated agonist of cell death
chr17_-_15596230 0.09 ENSMUST00000014917.8
delta like canonical Notch ligand 1
chrX_-_139857424 0.09 ENSMUST00000033805.15
ENSMUST00000112978.2
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
chr14_-_104081827 0.08 ENSMUST00000022718.11
endothelin receptor type B
chr6_+_108041998 0.08 ENSMUST00000049246.7
SET domain without mariner transposase fusion
chr4_+_119396913 0.08 ENSMUST00000137560.8
forkhead box J3
chr12_+_86725459 0.08 ENSMUST00000021681.4
vasohibin 1
chr11_-_59118988 0.07 ENSMUST00000163300.8
ENSMUST00000061242.8
ADP-ribosylation factor 1
chr1_+_38037086 0.07 ENSMUST00000027252.8
eukaryotic translation initiation factor 5B
chr2_-_150531280 0.07 ENSMUST00000046095.10
visual system homeobox 1
chr9_+_22322802 0.06 ENSMUST00000058868.9
RIKEN cDNA 9530077C05 gene
chr18_-_20995980 0.05 ENSMUST00000224530.2
trafficking protein particle complex 8
chr15_-_99372575 0.05 ENSMUST00000040313.6
BCDIN3 domain containing
chr5_-_22070602 0.05 ENSMUST00000030878.8
solute carrier family 26, member 5
chr17_+_18051266 0.05 ENSMUST00000172097.9
sperm acrosome associated 6
chr11_+_98337655 0.05 ENSMUST00000019456.5
growth factor receptor bound protein 7
chr9_+_5308828 0.05 ENSMUST00000162846.8
ENSMUST00000027012.14
caspase 4, apoptosis-related cysteine peptidase
chr4_-_43669141 0.04 ENSMUST00000056474.7
family with sequence similarity 221, member B
chr17_-_24866749 0.04 ENSMUST00000234121.2
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr11_-_50806962 0.04 ENSMUST00000116378.8
ENSMUST00000109128.8
zinc finger protein 2
chr13_-_64645606 0.04 ENSMUST00000180282.2
family with sequence similarity 240 member B
chr4_-_149994176 0.04 ENSMUST00000105685.2
splA/ryanodine receptor domain and SOCS box containing 1
chr11_+_102775991 0.04 ENSMUST00000100369.4
family with sequence similarity 187, member A
chr1_+_69866145 0.04 ENSMUST00000065425.12
ENSMUST00000113940.4
sperm associated antigen 16
chr14_+_8555284 0.04 ENSMUST00000144914.3
predicted gene 281
chr11_+_49138278 0.04 ENSMUST00000109194.2
mannoside acetylglucosaminyltransferase 1
chr16_-_94657531 0.04 ENSMUST00000232562.2
ENSMUST00000165538.3
potassium inwardly-rectifying channel, subfamily J, member 6
chr15_+_82225380 0.04 ENSMUST00000050349.3
PH domain containing endocytic trafficking adaptor 2
chr17_+_37253802 0.04 ENSMUST00000040498.12
ring finger protein 39
chr18_+_70605691 0.04 ENSMUST00000164223.8
StAR-related lipid transfer (START) domain containing 6
chr15_-_76259126 0.03 ENSMUST00000071119.8
testis-specific serine kinase 5
chr8_-_44029744 0.03 ENSMUST00000049577.3
a disintegrin and metallopeptidase domain 26A (testase 3)
chr6_+_29398919 0.03 ENSMUST00000181464.8
ENSMUST00000180829.8
coiled-coil domain containing 136
chr9_-_44891626 0.03 ENSMUST00000002101.12
ENSMUST00000160886.2
CD3 antigen, gamma polypeptide
chr15_-_60793115 0.03 ENSMUST00000096418.5
alpha-1-B glycoprotein
chr18_+_70605722 0.03 ENSMUST00000174118.8
StAR-related lipid transfer (START) domain containing 6
chr16_-_33787399 0.03 ENSMUST00000023510.7
uridine monophosphate synthetase
chr9_+_36604516 0.03 ENSMUST00000034620.5
acrosomal vesicle protein 1
chr1_-_161807205 0.03 ENSMUST00000162676.2
RIKEN cDNA 4930558K02 gene
chr6_+_24528143 0.03 ENSMUST00000031696.10
ankyrin repeat and SOCS box-containing 15
chr13_-_104365310 0.03 ENSMUST00000022226.6
peptidylprolyl isomerase domain and WD repeat containing 1
chr14_-_52728503 0.03 ENSMUST00000073571.6
olfactory receptor 1507
chr15_-_101694895 0.03 ENSMUST00000071104.6
keratin 72
chr14_-_70449438 0.03 ENSMUST00000227929.2
sorbin and SH3 domain containing 3
chr7_+_140427711 0.02 ENSMUST00000026555.12
outer dense fiber of sperm tails 3
chr7_+_140427729 0.02 ENSMUST00000106049.2
outer dense fiber of sperm tails 3
chr17_+_48607405 0.02 ENSMUST00000170941.3
triggering receptor expressed on myeloid cells-like 2
chr8_+_71156071 0.02 ENSMUST00000212436.2
IQ motif containing N
chr15_-_88838605 0.02 ENSMUST00000109371.8
tubulin tyrosine ligase-like family, member 8
chr10_+_62896492 0.02 ENSMUST00000219687.2
ENSMUST00000219045.2
phenazine biosynthesis-like protein domain containing 1
chr19_-_12069216 0.02 ENSMUST00000208703.3
ENSMUST00000219005.2
ENSMUST00000219155.2
ENSMUST00000217952.2
ENSMUST00000112952.4
olfactory receptor 1426
chr9_+_37278647 0.02 ENSMUST00000051839.9
hepatocyte cell adhesion molecule
chr8_+_41246310 0.02 ENSMUST00000056331.8
a disintegrin and metallopeptidase domain 20
chr19_-_57170725 0.02 ENSMUST00000133369.2
actin-binding LIM protein 1
chr7_+_102420428 0.02 ENSMUST00000213432.2
olfactory receptor 561
chr9_-_40366966 0.02 ENSMUST00000165104.8
ENSMUST00000045682.7
GRAM domain containing 1B
chr5_+_30486375 0.02 ENSMUST00000101448.5
dynein regulatory complex subunit 1
chr14_+_26789345 0.02 ENSMUST00000226105.2
interleukin 17 receptor D
chr9_-_58448224 0.02 ENSMUST00000039788.11
CD276 antigen
chr8_+_41205245 0.02 ENSMUST00000096663.5
a disintegrin and metallopeptidase domain 25 (testase 2)
chr17_+_37253916 0.02 ENSMUST00000173072.2
ring finger protein 39
chr7_-_141472218 0.02 ENSMUST00000151890.3
toll interacting protein
chr6_+_90439544 0.02 ENSMUST00000032174.12
Kruppel-like factor 15
chr6_+_90439596 0.02 ENSMUST00000203039.3
Kruppel-like factor 15
chr19_+_13742643 0.02 ENSMUST00000215930.2
olfactory receptor 1495
chr13_-_92620507 0.02 ENSMUST00000040106.9
family with sequence similarity 151, member B
chr10_-_70428611 0.02 ENSMUST00000162251.8
phytanoyl-CoA hydroxylase interacting protein-like
chr7_-_111758241 0.02 ENSMUST00000033036.7
dickkopf WNT signaling pathway inhibitor 3
chr5_-_35836761 0.02 ENSMUST00000114233.3
HtrA serine peptidase 3
chrX_+_76908364 0.02 ENSMUST00000114039.3
predicted gene 14744
chr18_+_70605630 0.02 ENSMUST00000168249.9
StAR-related lipid transfer (START) domain containing 6
chr9_+_39642274 0.02 ENSMUST00000217257.2
olfactory receptor 150
chr8_+_41276027 0.01 ENSMUST00000066814.7
a disintegrin and metallopeptidase domain 39
chr3_+_5283606 0.01 ENSMUST00000026284.13
zinc finger homeodomain 4
chr7_-_48493388 0.01 ENSMUST00000167786.4
cysteine and glycine-rich protein 3
chrX_-_76968668 0.01 ENSMUST00000063127.4
RIKEN cDNA 5430402E10 gene
chr9_+_110673565 0.01 ENSMUST00000176403.8
protease, serine 46
chr7_+_106413336 0.01 ENSMUST00000166880.3
ENSMUST00000075414.8
olfactory receptor 701
chr19_-_12069012 0.01 ENSMUST00000220005.2
olfactory receptor 1426
chr5_+_11234174 0.01 ENSMUST00000168407.3
predicted gene 5861
chr11_-_100332619 0.01 ENSMUST00000107398.8
5'-nucleotidase, cytosolic IIIB
chrX_+_106836189 0.01 ENSMUST00000101292.9
terminal nucleotidyltransferase 5D
chr19_-_8196196 0.01 ENSMUST00000113298.9
solute carrier family 22. member 29
chr11_+_100332709 0.01 ENSMUST00000001599.4
ENSMUST00000107395.3
kelch-like 10
chr11_+_104983022 0.01 ENSMUST00000021029.6
EF-hand calcium binding domain 3
chr12_+_111540920 0.01 ENSMUST00000075281.8
ENSMUST00000084953.13
MAP/microtubule affinity regulating kinase 3
chr6_-_83504756 0.01 ENSMUST00000152029.2
actin, gamma 2, smooth muscle, enteric
chr8_-_107007596 0.01 ENSMUST00000212896.2
sphingomyelin phosphodiesterase 3, neutral
chr6_-_143892814 0.01 ENSMUST00000124233.7
ENSMUST00000144289.4
ENSMUST00000111748.8
SRY (sex determining region Y)-box 5
chr3_+_5283577 0.01 ENSMUST00000175866.8
zinc finger homeodomain 4
chr3_-_153610368 0.01 ENSMUST00000188338.7
mutS homolog 4
chr15_-_76419131 0.01 ENSMUST00000230604.2
transmembrane protein 249
chr10_+_63293284 0.01 ENSMUST00000105440.8
catenin (cadherin associated protein), alpha 3
chr6_+_103674695 0.01 ENSMUST00000205098.2
cell adhesion molecule L1-like
chr3_-_153610528 0.01 ENSMUST00000190449.2
mutS homolog 4
chr6_-_68784692 0.00 ENSMUST00000103334.4
immunoglobulin kappa chain variable 4-90
chr17_-_28128180 0.00 ENSMUST00000114848.8
TATA-box binding protein associated factor 11
chr1_-_75208734 0.00 ENSMUST00000180101.3
RIKEN cDNA A630095N17 gene
chr19_+_12186932 0.00 ENSMUST00000072316.5
olfactory receptor 1431
chr8_+_41128099 0.00 ENSMUST00000051614.5
a disintegrin and metallopeptidase domain 24 (testase 1)
chr4_-_138351313 0.00 ENSMUST00000030533.12
von Willebrand factor A domain containing 5B1
chr1_-_155627430 0.00 ENSMUST00000195275.2
LIM homeobox protein 4
chr18_+_70605476 0.00 ENSMUST00000114959.9
StAR-related lipid transfer (START) domain containing 6
chr5_-_121641461 0.00 ENSMUST00000079368.5
a disintegrin and metallopeptidase domain 1b
chr7_-_48145873 0.00 ENSMUST00000186394.2
MAS-related GPR, member X2
chr11_+_49426014 0.00 ENSMUST00000074543.2
olfactory receptor 1382
chr17_+_27248233 0.00 ENSMUST00000053683.7
ENSMUST00000236222.2
gametogenetin binding protein 1
chr10_-_75658355 0.00 ENSMUST00000160211.2
glutathione S-transferase, theta 4
chr7_+_65693350 0.00 ENSMUST00000206065.2
predicted gene 45213

Network of associatons between targets according to the STRING database.

First level regulatory network of Zbtb12

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0070237 positive regulation of activation-induced cell death of T cells(GO:0070237)
0.1 0.5 GO:1902303 negative regulation of potassium ion export(GO:1902303)
0.1 0.8 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 0.6 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.1 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.1 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.0 0.1 GO:0002436 immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265) negative regulation of eosinophil activation(GO:1902567) positive regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000451)
0.0 1.1 GO:0031424 keratinization(GO:0031424)
0.0 0.1 GO:1902220 positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902220)
0.0 0.1 GO:0021698 cerebellar cortex structural organization(GO:0021698)
0.0 0.1 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.1 GO:0097212 cleavage furrow ingression(GO:0036090) lysosomal membrane organization(GO:0097212)
0.0 0.1 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.1 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.0 0.2 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.3 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.1 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.0 0.1 GO:0015755 fructose transport(GO:0015755)
0.0 0.6 GO:0045577 regulation of B cell differentiation(GO:0045577)
0.0 0.0 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 GO:0042101 T cell receptor complex(GO:0042101)
0.0 1.1 GO:0001533 cornified envelope(GO:0001533)
0.0 0.1 GO:0097422 tubular endosome(GO:0097422)
0.0 0.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.1 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.0 GO:1990716 axonemal central apparatus(GO:1990716)
0.0 0.6 GO:0032809 neuronal cell body membrane(GO:0032809)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 1.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 1.1 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.1 GO:0035717 chemokine (C-C motif) ligand 7 binding(GO:0035717)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.0 0.6 GO:0008430 selenium binding(GO:0008430)
0.0 0.1 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.0 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 ST JAK STAT PATHWAY Jak-STAT Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.1 REACTOME BETA DEFENSINS Genes involved in Beta defensins