ISMARA results: Zfp384

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avrg: GFI1 WT vs 36n/n vs KD

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Results for Zfp384

Z-value: 1.82

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Transcription factors associated with Zfp384

Gene Symbol	Gene ID	Gene Info
Zfp384 Ensembl NCBI MGI UniProt	ENSMUSG00000038346.19	zinc finger protein 384

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Zfp384	mm39_v1_chr6_+_124986193_124986216	-0.58	3.0e-01	Click!

Activity profile of Zfp384 motif

Sorted Z-values of Zfp384 motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr13_-_21934675 Show fit	1.60	ENSMUST00000102983.2	H4c12 Ensembl NCBI MGI UniProt Show fit	H4 clustered histone 12
chr13_-_23806530 Show fit	1.34	ENSMUST00000062045.4	H1f4 Ensembl NCBI MGI UniProt Show fit	H1.4 linker histone, cluster member
chr6_+_88175312 Show fit	1.24	ENSMUST00000203480.2 ENSMUST00000015197.9	Gata2 Ensembl NCBI MGI UniProt Show fit	GATA binding protein 2
chr3_-_20296337 Show fit	1.09	ENSMUST00000001921.3	Cpa3 Ensembl NCBI MGI UniProt Show fit	carboxypeptidase A3, mast cell
chr13_+_23759930 Show fit	1.08	ENSMUST00000105105.4	H3c4 Ensembl NCBI MGI UniProt Show fit	H3 clustered histone 4
chr13_+_23728222 Show fit	1.06	ENSMUST00000075558.5	H3c7 Ensembl NCBI MGI UniProt Show fit	H3 clustered histone 7
chr13_+_23922783 Show fit	1.02	ENSMUST00000040914.3	H1f2 Ensembl NCBI MGI UniProt Show fit	H1.2 linker histone, cluster member
chr13_-_23758370 Show fit	0.87	ENSMUST00000105106.2	H2bc7 Ensembl NCBI MGI UniProt Show fit	H2B clustered histone 7
chr13_+_23718038 Show fit	0.85	ENSMUST00000073261.3	H2ac10 Ensembl NCBI MGI UniProt Show fit	H2A clustered histone 10
chr6_+_129326927 Show fit	0.78	ENSMUST00000065289.6	Clec12a Ensembl NCBI MGI UniProt Show fit	C-type lectin domain family 12, member a

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of Zfp384

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.2	GO:0035854	eosinophil fate commitment(GO:0035854)
0.1	1.1	GO:0002002	regulation of angiotensin levels in blood(GO:0002002)
0.0	0.7	GO:0021796	cerebral cortex regionalization(GO:0021796)
0.0	0.7	GO:0042744	hydrogen peroxide catabolic process(GO:0042744)
0.0	0.7	GO:0032981	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.2	0.6	GO:0030573	bile acid catabolic process(GO:0030573)
0.1	0.6	GO:0015961	diadenosine polyphosphate catabolic process(GO:0015961)
0.2	0.5	GO:0097045	activation of blood coagulation via clotting cascade(GO:0002543) phosphatidylserine exposure on blood platelet(GO:0097045)
0.1	0.5	GO:2000680	regulation of rubidium ion transport(GO:2000680)
0.0	0.5	GO:0052697	flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)

Showing 1 to 10 of 196 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.5	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	0.8	GO:0005747	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0	0.7	GO:0005766	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.1	0.6	GO:0097451	glial limiting end-foot(GO:0097451)
0.0	0.6	GO:0005782	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0	0.6	GO:0070469	respiratory chain(GO:0070469)
0.2	0.5	GO:0031904	endosome lumen(GO:0031904)
0.0	0.5	GO:0016272	prefoldin complex(GO:0016272)
0.0	0.5	GO:0070765	gamma-secretase complex(GO:0070765)
0.0	0.5	GO:0034385	very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)

Showing 1 to 10 of 62 entries

Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.4	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.0	1.1	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.9	GO:0043022	ribosome binding(GO:0043022)
0.0	0.8	GO:0008137	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.8	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.7	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.2	0.6	GO:0008396	oxysterol 7-alpha-hydroxylase activity(GO:0008396)
0.1	0.6	GO:0047710	bis(5'-adenosyl)-triphosphatase activity(GO:0047710)
0.0	0.6	GO:0008430	selenium binding(GO:0008430)
0.0	0.6	GO:0004303	estradiol 17-beta-dehydrogenase activity(GO:0004303)

Showing 1 to 10 of 116 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

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Total log-likelihood	Term	Description
2.1	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
1.5	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.6	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.5	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.5	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.3	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.3	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.3	PID S1P S1P4 PATHWAY	S1P4 pathway

Showing 1 to 8 of 8 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.5	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	1.1	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.1	0.8	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.6	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	0.6	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.5	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.5	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.4	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.4	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.1	0.3	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion

Showing 1 to 10 of 19 entries

Results for Zfp384

Z-value: 1.82

Motif logo

Transcription factors associated with Zfp384

Activity-expression correlation:

Activity profile of Zfp384 motif

Sorted Z-values of Zfp384 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Zfp384

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: