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avrg: GFI1 WT vs 36n/n vs KD

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Results for Zfp423

Z-value: 0.11

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Transcription factors associated with Zfp423

Gene Symbol Gene ID Gene Info
ENSMUSG00000045333.16 zinc finger protein 423

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zfp423mm39_v1_chr8_-_88686188_88686223-0.553.3e-01Click!

Activity profile of Zfp423 motif

Sorted Z-values of Zfp423 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_10079091 0.12 ENSMUST00000025567.9
fatty acid desaturase 2
chr6_-_52217821 0.10 ENSMUST00000121043.2
homeobox A10
chr2_+_154633265 0.07 ENSMUST00000140713.3
ENSMUST00000137333.8
hnRNP-associated with lethal yellow
nonagouti
chr6_-_124391994 0.07 ENSMUST00000035861.6
ENSMUST00000112532.8
ENSMUST00000080557.12
peroxisomal biogenesis factor 5
chr7_-_120269462 0.06 ENSMUST00000127845.2
ENSMUST00000208635.2
ENSMUST00000033178.4
PDZ domain containing 9
chr2_+_163389068 0.05 ENSMUST00000109411.8
ENSMUST00000018094.13
hepatic nuclear factor 4, alpha
chr7_-_126625617 0.05 ENSMUST00000032916.6
MYC-associated zinc finger protein (purine-binding transcription factor)
chr2_-_29142965 0.05 ENSMUST00000155949.2
ENSMUST00000154682.8
ENSMUST00000028141.6
ENSMUST00000071201.5
RIKEN cDNA 6530402F18 gene
netrin G2
chr6_+_7844759 0.05 ENSMUST00000040159.6
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr12_-_14202041 0.04 ENSMUST00000020926.8
LRAT domain containing 1
chr4_+_129407374 0.04 ENSMUST00000062356.7
MARCKS-like 1
chr19_+_6451667 0.04 ENSMUST00000113471.3
ENSMUST00000113469.3
RAS, guanyl releasing protein 2
chr19_+_10019023 0.04 ENSMUST00000237672.2
fatty acid desaturase 3
chr4_-_6990774 0.04 ENSMUST00000039987.4
thymocyte selection-associated high mobility group box
chr4_-_155845500 0.03 ENSMUST00000030903.12
ATPase family, AAA domain containing 3A
chr11_-_76737794 0.03 ENSMUST00000021201.6
carboxypeptidase D
chr9_+_120321557 0.03 ENSMUST00000007139.6
eukaryotic translation initiation factor 1B
chrX_-_74174450 0.03 ENSMUST00000114092.8
ENSMUST00000132501.8
ENSMUST00000153318.8
ENSMUST00000155742.2
membrane protein, palmitoylated
chr2_-_30249202 0.02 ENSMUST00000100215.11
ENSMUST00000113620.10
ENSMUST00000163668.3
ENSMUST00000028214.15
ENSMUST00000113621.10
SH3-domain GRB2-like endophilin B2
chr1_+_156386414 0.02 ENSMUST00000166172.9
ENSMUST00000027888.13
v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene)
chr6_+_86605146 0.02 ENSMUST00000043400.9
aspartic peptidase, retroviral-like 1
chr19_+_7245591 0.02 ENSMUST00000066646.12
REST corepressor 2
chr2_+_93017887 0.02 ENSMUST00000150462.8
ENSMUST00000111266.8
transformation related protein 53 inducible protein 11
chr3_+_94882038 0.02 ENSMUST00000072287.12
phosphatidylinositol 4-kinase beta
chr12_+_102915102 0.02 ENSMUST00000101099.12
unc-79 homolog
chr4_-_148711211 0.02 ENSMUST00000186947.7
ENSMUST00000105699.8
TAR DNA binding protein
chr11_+_54793743 0.02 ENSMUST00000149324.3
glutathione peroxidase 3
chr4_-_116982804 0.02 ENSMUST00000183310.2
BTB (POZ) domain containing 19
chr19_+_41818409 0.02 ENSMUST00000087155.5
frequently rearranged in advanced T cell lymphomas
chr19_-_5781503 0.02 ENSMUST00000162976.2
zinc ribbon domain containing 2
chr2_+_93017916 0.02 ENSMUST00000090554.11
transformation related protein 53 inducible protein 11
chr10_+_80972368 0.02 ENSMUST00000119606.8
ENSMUST00000146895.2
ENSMUST00000121840.8
zinc finger and BTB domain containing 7a
chr13_+_41403317 0.02 ENSMUST00000165561.4
small integral membrane protein 13
chr4_+_126915104 0.02 ENSMUST00000030623.8
splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)
chr5_-_24628483 0.02 ENSMUST00000198990.2
cyclin-dependent kinase 5
chrX_+_100298134 0.02 ENSMUST00000062000.6
forkhead box O4
chr4_-_106321363 0.01 ENSMUST00000049507.6
proprotein convertase subtilisin/kexin type 9
chr19_+_10018914 0.01 ENSMUST00000115995.4
fatty acid desaturase 3
chr13_+_3588063 0.01 ENSMUST00000223396.2
ENSMUST00000059515.8
ENSMUST00000222365.2
guanosine diphosphate (GDP) dissociation inhibitor 2
chr7_-_141023199 0.01 ENSMUST00000106005.9
p53 induced death domain protein 1
chr7_+_18737944 0.01 ENSMUST00000053713.5
interferon regulatory factor 2 binding protein 1
chrX_-_74174524 0.01 ENSMUST00000114091.8
membrane protein, palmitoylated
chr9_-_37464200 0.01 ENSMUST00000065668.12
neurogranin
chr4_-_148711453 0.01 ENSMUST00000165113.8
ENSMUST00000172073.8
ENSMUST00000105702.9
ENSMUST00000084125.10
TAR DNA binding protein
chr15_-_98676007 0.01 ENSMUST00000226655.2
ENSMUST00000228546.2
ENSMUST00000023732.12
ENSMUST00000226610.2
wingless-type MMTV integration site family, member 10B
chr10_-_14581203 0.01 ENSMUST00000149485.2
ENSMUST00000154132.8
vesicle (multivesicular body) trafficking 1
chr8_-_41469786 0.01 ENSMUST00000117735.8
mitochondrial tumor suppressor 1
chr7_-_128062916 0.01 ENSMUST00000205835.2
Tia1 cytotoxic granule-associated RNA binding protein-like 1
chr6_+_113448388 0.01 ENSMUST00000058300.14
interleukin 17 receptor C
chr5_+_67418137 0.01 ENSMUST00000161369.3
transmembrane protein 33
chr7_-_5017642 0.01 ENSMUST00000207412.2
ENSMUST00000077385.15
ENSMUST00000165320.3
Flt3 interacting zinc finger protein 1
chr11_+_81992662 0.00 ENSMUST00000000194.4
chemokine (C-C motif) ligand 12
chr7_-_19192672 0.00 ENSMUST00000239292.2
ENSMUST00000085715.7
MAP/microtubule affinity regulating kinase 4
chr15_-_78602313 0.00 ENSMUST00000229441.2
leucine rich repeat and fibronectin type III, extracellular 2
chr15_+_78128990 0.00 ENSMUST00000096357.12
neutrophil cytosolic factor 4
chr10_+_80973787 0.00 ENSMUST00000117956.2
zinc finger and BTB domain containing 7a
chr11_-_99228756 0.00 ENSMUST00000100482.3
keratin 26
chr3_+_114697710 0.00 ENSMUST00000081752.13
olfactomedin 3
chr17_-_25652750 0.00 ENSMUST00000159610.8
ENSMUST00000159048.8
ENSMUST00000078496.12
calcium channel, voltage-dependent, T type, alpha 1H subunit
chrX_-_74174608 0.00 ENSMUST00000033775.9
membrane protein, palmitoylated
chr2_+_106523532 0.00 ENSMUST00000111063.8
metallophosphoesterase domain containing 2
chr11_-_43727071 0.00 ENSMUST00000167574.2
adrenergic receptor, alpha 1b
chr17_-_35293447 0.00 ENSMUST00000007259.4
lymphocyte antigen 6 complex, locus G6D
chr6_+_110622533 0.00 ENSMUST00000071076.13
ENSMUST00000172951.2
glutamate receptor, metabotropic 7
chr14_+_70791127 0.00 ENSMUST00000161069.8
lysine demethylase and nuclear receptor corepressor
chr13_-_114595122 0.00 ENSMUST00000231252.2
follistatin
chr9_-_99758200 0.00 ENSMUST00000054819.10
SRY (sex determining region Y)-box 14
chr16_+_17307503 0.00 ENSMUST00000023448.15
apoptosis-inducing factor, mitochondrion-associated 3
chr11_-_33153587 0.00 ENSMUST00000037746.8
T cell leukemia, homeobox 3
chr17_-_23939700 0.00 ENSMUST00000201734.4
RIKEN cDNA 1520401A03 gene
chr17_-_32385826 0.00 ENSMUST00000087723.5
notch 3
chr15_+_78129040 0.00 ENSMUST00000133618.3
neutrophil cytosolic factor 4
chr6_+_6863769 0.00 ENSMUST00000031768.8
distal-less homeobox 6
chr16_-_45664664 0.00 ENSMUST00000036355.13
pleckstrin homology like domain, family B, member 2
chr4_+_150999019 0.00 ENSMUST00000135169.8
tumor necrosis factor receptor superfamily, member 9
chr1_+_167426019 0.00 ENSMUST00000111386.8
ENSMUST00000111384.8
retinoid X receptor gamma
chr15_-_98675142 0.00 ENSMUST00000166022.2
wingless-type MMTV integration site family, member 10B
chr11_+_102727122 0.00 ENSMUST00000021302.15
ENSMUST00000107072.2
HIG1 domain family, member 1B
chr2_+_180141686 0.00 ENSMUST00000029084.9
neurotensin receptor 1
chr4_+_154321982 0.00 ENSMUST00000152159.8
multiple EGF-like-domains 6
chr18_-_66072858 0.00 ENSMUST00000237506.2
retina and anterior neural fold homeobox

Network of associatons between targets according to the STRING database.

First level regulatory network of Zfp423

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0040030 regulation of molecular function, epigenetic(GO:0040030)
0.0 0.1 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.0 0.1 GO:1902569 regulation of activation of JAK2 kinase activity(GO:0010534) activation of JAK2 kinase activity(GO:0042977) negative regulation of activation of JAK2 kinase activity(GO:1902569)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0070540 stearic acid binding(GO:0070540)
0.0 0.1 GO:0031782 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 0.1 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768)
0.0 0.1 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)