Project
avrg: 12D miR HR13_24
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Results for AGCACCA
Z-value: 3.02
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miRNA associated with seed AGCACCA
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr3_+_104638658 Show fit | 3.90 |
ENSMUST00000046212.1
|
solute carrier family 16 (monocarboxylic acid transporters), member 1 |
|
| chrX_-_104201126 Show fit | 3.62 |
ENSMUST00000056502.6
ENSMUST00000118314.1 |
expressed sequence C77370 |
|
| chr18_+_22345089 Show fit | 3.34 |
ENSMUST00000120223.1
ENSMUST00000097655.3 |
additional sex combs like 3 (Drosophila) |
|
| chr5_+_30711564 Show fit | 3.28 |
ENSMUST00000114729.1
|
dihydropyrimidinase-like 5 |
|
| chr11_-_72411695 Show fit | 3.16 |
ENSMUST00000108500.1
ENSMUST00000050226.6 |
smoothelin-like 2 |
|
| chr5_-_134747241 Show fit | 3.15 |
ENSMUST00000015138.9
|
elastin |
|
| chr3_-_73056943 Show fit | 3.15 |
ENSMUST00000059407.7
|
SLIT and NTRK-like family, member 3 |
|
| chr5_+_118169712 Show fit | 3.11 |
ENSMUST00000054836.6
|
harakiri, BCL2 interacting protein (contains only BH3 domain) |
|
| chr7_-_84086494 Show fit | 3.10 |
ENSMUST00000064174.5
|
RIKEN cDNA 9930013L23 gene |
|
| chr7_+_141475240 Show fit | 3.08 |
ENSMUST00000026585.7
|
tetraspanin 4 |
Network of associatons between targets according to the STRING database.
First level regulatory network of AGCACCA
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.7 | GO:0030833 | regulation of actin filament polymerization(GO:0030833) |
| 0.6 | 3.6 | GO:0042276 | error-prone translesion synthesis(GO:0042276) |
| 0.3 | 3.2 | GO:0035879 | lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879) |
| 0.5 | 3.1 | GO:0051365 | cellular response to potassium ion starvation(GO:0051365) |
| 0.1 | 2.9 | GO:0006730 | one-carbon metabolic process(GO:0006730) |
| 0.2 | 2.8 | GO:0060732 | positive regulation of inositol phosphate biosynthetic process(GO:0060732) |
| 0.2 | 2.6 | GO:0060159 | regulation of dopamine receptor signaling pathway(GO:0060159) |
| 0.2 | 2.6 | GO:0035988 | chondrocyte proliferation(GO:0035988) |
| 0.1 | 2.4 | GO:0010259 | multicellular organism aging(GO:0010259) |
| 0.0 | 2.4 | GO:0007019 | microtubule depolymerization(GO:0007019) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 4.0 | GO:0032591 | dendritic spine membrane(GO:0032591) |
| 0.6 | 3.6 | GO:0016035 | zeta DNA polymerase complex(GO:0016035) |
| 0.8 | 3.2 | GO:0071953 | elastic fiber(GO:0071953) |
| 0.1 | 3.0 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
| 0.0 | 2.9 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
| 0.1 | 2.4 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.0 | 2.4 | GO:0043034 | costamere(GO:0043034) |
| 0.0 | 2.4 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
| 0.2 | 2.3 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 0.0 | 1.9 | GO:0005604 | basement membrane(GO:0005604) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 7.8 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.0 | 4.8 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
| 0.0 | 3.7 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.5 | 3.3 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
| 0.2 | 2.9 | GO:0016151 | nickel cation binding(GO:0016151) |
| 0.0 | 2.9 | GO:0016765 | transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765) |
| 0.7 | 2.8 | GO:0004999 | vasoactive intestinal polypeptide receptor activity(GO:0004999) |
| 0.0 | 2.8 | GO:0016810 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810) |
| 0.1 | 2.5 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.2 | 2.3 | GO:0005314 | high-affinity glutamate transmembrane transporter activity(GO:0005314) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 7.2 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.1 | 4.7 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.0 | 3.9 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.1 | 2.7 | PID TCR CALCIUM PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.0 | 2.5 | PID ATF2 PATHWAY | ATF-2 transcription factor network |
| 0.0 | 2.5 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.0 | 2.5 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.0 | 2.0 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.1 | 1.6 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.0 | 1.4 | PID E2F PATHWAY | E2F transcription factor network |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 5.5 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.2 | 3.6 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.3 | 3.3 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.1 | 2.8 | REACTOME SYNTHESIS OF PA | Genes involved in Synthesis of PA |
| 0.0 | 2.5 | REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS | Genes involved in Amino acid and oligopeptide SLC transporters |
| 0.0 | 2.2 | REACTOME GLUCAGON TYPE LIGAND RECEPTORS | Genes involved in Glucagon-type ligand receptors |
| 0.1 | 1.9 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.1 | 1.8 | REACTOME G0 AND EARLY G1 | Genes involved in G0 and Early G1 |
| 0.1 | 1.7 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 0.0 | 1.7 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |