ISMARA results: Ahr

Project

avrg: 12D miR HR13_24

Navigation

Downloads

Results for Ahr

Z-value: 11.16

Motif logo

Transcription factors associated with Ahr

Gene Symbol	Gene ID	Gene Info
Ahr Ensembl NCBI MGI UniProt	ENSMUSG00000019256.11	aryl-hydrocarbon receptor

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Ahr	mm10_v2_chr12_-_35534973_35535058	0.40	2.3e-01	Click!

Activity profile of Ahr motif

Sorted Z-values of Ahr motif

Top targets:

Search:

Show entries

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr15_+_82275197 Show fit	17.52	ENSMUST00000116423.1	Sept3 Ensembl NCBI MGI UniProt Show fit	septin 3
chr1_-_155232710 Show fit	15.67	ENSMUST00000035914.3	BC034090 Ensembl NCBI MGI UniProt Show fit	cDNA sequence BC034090
chr15_+_62037986 Show fit	15.19	ENSMUST00000182956.1 ENSMUST00000182075.1 ENSMUST00000180432.2 ENSMUST00000181416.2 ENSMUST00000181657.2	Pvt1 Ensembl NCBI MGI UniProt Show fit	plasmacytoma variant translocation 1
chr7_+_64501687 Show fit	15.02	ENSMUST00000032732.8	Apba2 Ensembl NCBI MGI UniProt Show fit	amyloid beta (A4) precursor protein-binding, family A, member 2
chr14_+_64588112 Show fit	14.02	ENSMUST00000181808.1	A930011O12Rik Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA A930011O12 gene
chr4_+_124657646 Show fit	13.68	ENSMUST00000053491.7	Pou3f1 Ensembl NCBI MGI UniProt Show fit	POU domain, class 3, transcription factor 1
chr11_-_31370066 Show fit	13.52	ENSMUST00000020546.2	Stc2 Ensembl NCBI MGI UniProt Show fit	stanniocalcin 2
chr10_-_87493651 Show fit	13.41	ENSMUST00000020243.7	Ascl1 Ensembl NCBI MGI UniProt Show fit	achaete-scute complex homolog 1 (Drosophila)
chr15_+_26309039 Show fit	12.94	ENSMUST00000140840.1 ENSMUST00000152841.1	March11 Ensembl NCBI MGI UniProt Show fit	membrane-associated ring finger (C3HC4) 11
chr19_+_28835074 Show fit	12.37	ENSMUST00000025875.4	Slc1a1 Ensembl NCBI MGI UniProt Show fit	solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of Ahr

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	28.6	GO:0006284	base-excision repair(GO:0006284)
1.5	24.0	GO:0090308	regulation of methylation-dependent chromatin silencing(GO:0090308)
0.2	24.0	GO:0006364	rRNA processing(GO:0006364)
0.6	20.4	GO:0000387	spliceosomal snRNP assembly(GO:0000387)
0.2	16.2	GO:0008033	tRNA processing(GO:0008033)
1.9	15.5	GO:0033313	meiotic cell cycle checkpoint(GO:0033313)
1.6	14.3	GO:0033227	dsRNA transport(GO:0033227)
4.5	13.5	GO:2000118	regulation of sodium-dependent phosphate transport(GO:2000118)
4.5	13.5	GO:0021530	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
2.7	13.4	GO:2000434	regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)

Showing 1 to 10 of 710 entries

Gene overrepresentation in cellular component category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	56.2	GO:0001650	fibrillar center(GO:0001650)
0.1	54.2	GO:0005730	nucleolus(GO:0005730)
0.5	36.1	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.5	33.3	GO:0005657	replication fork(GO:0005657)
0.5	33.1	GO:0030684	preribosome(GO:0030684)
4.1	32.8	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.1	31.0	GO:0005667	transcription factor complex(GO:0005667)
0.5	25.3	GO:0022626	cytosolic ribosome(GO:0022626)
0.5	24.7	GO:0009295	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
5.8	23.3	GO:0099569	presynaptic cytoskeleton(GO:0099569)

Showing 1 to 10 of 296 entries

Gene overrepresentation in molecular function category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	62.2	GO:0003735	structural constituent of ribosome(GO:0003735)
0.1	59.4	GO:0003723	RNA binding(GO:0003723)
3.0	26.7	GO:0051575	5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
4.3	26.1	GO:0031493	nucleosomal histone binding(GO:0031493)
0.4	20.4	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.6	19.8	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.3	19.4	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.4	18.9	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.3	16.8	GO:0019212	phosphatase inhibitor activity(GO:0019212)
0.4	16.7	GO:0045182	translation regulator activity(GO:0045182)

Showing 1 to 10 of 437 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	80.4	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.6	28.3	PID AURORA B PATHWAY	Aurora B signaling
0.2	18.0	PID INSULIN PATHWAY	Insulin Pathway
0.3	16.4	PID PLK1 PATHWAY	PLK1 signaling events
0.1	15.9	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.2	14.9	PID P53 REGULATION PATHWAY	p53 pathway
0.3	14.7	PID ILK PATHWAY	Integrin-linked kinase signaling
0.4	14.5	PID BARD1 PATHWAY	BARD1 signaling events
0.3	12.7	PID EPHA FWDPATHWAY	EPHA forward signaling
0.1	12.6	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Showing 1 to 10 of 75 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	37.4	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.4	33.7	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.5	29.5	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
3.6	28.7	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.5	27.6	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.5	23.8	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.3	19.1	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.3	17.8	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.4	15.2	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.3	14.8	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels

Showing 1 to 10 of 151 entries

Results for Ahr

Z-value: 11.16

Motif logo

Transcription factors associated with Ahr

Activity-expression correlation:

Activity profile of Ahr motif

Sorted Z-values of Ahr motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Ahr

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: