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avrg: 12D miR HR13_24
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Results for Cebpe
Z-value: 2.96
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Transcription factors associated with Cebpe
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Cebpe | mm10_v2_chr14_-_54712139_54712174 | 0.03 | 9.2e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr14_+_41105359 Show fit | 5.78 |
ENSMUST00000047286.6
|
methionine adenosyltransferase I, alpha |
|
| chr16_+_32756336 Show fit | 5.39 |
ENSMUST00000135753.1
|
mucin 4 |
|
| chr7_+_49975228 Show fit | 4.44 |
ENSMUST00000107603.1
|
NEL-like 1 |
|
| chr5_-_86906937 Show fit | 4.11 |
ENSMUST00000031181.9
ENSMUST00000113333.1 |
UDP glucuronosyltransferase 2 family, polypeptide B34 |
|
| chr4_+_106733883 Show fit | 3.95 |
ENSMUST00000047620.2
|
family with sequence simliarity 151, member A |
|
| chrX_+_164139321 Show fit | 3.62 |
ENSMUST00000112271.3
|
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 |
|
| chr1_-_158814469 Show fit | 3.44 |
ENSMUST00000161589.2
|
pappalysin 2 |
|
| chr4_+_110397764 Show fit | 3.22 |
ENSMUST00000097920.2
ENSMUST00000080744.6 |
ATP/GTP binding protein-like 4 |
|
| chr11_-_31824518 Show fit | 3.09 |
ENSMUST00000134944.1
|
RIKEN cDNA D630024D03 gene |
|
| chr6_-_78468863 Show fit | 3.04 |
ENSMUST00000032089.2
|
regenerating islet-derived 3 gamma |
Network of associatons between targets according to the STRING database.
First level regulatory network of Cebpe
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 9.5 | GO:0007608 | sensory perception of smell(GO:0007608) |
| 1.1 | 6.8 | GO:0002838 | negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838) |
| 1.5 | 6.0 | GO:0035609 | C-terminal protein deglutamylation(GO:0035609) |
| 1.4 | 5.8 | GO:0006556 | S-adenosylmethionine biosynthetic process(GO:0006556) |
| 0.4 | 5.0 | GO:0033689 | negative regulation of osteoblast proliferation(GO:0033689) |
| 0.3 | 4.1 | GO:0052697 | flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697) |
| 0.9 | 3.6 | GO:0015827 | aromatic amino acid transport(GO:0015801) tryptophan transport(GO:0015827) |
| 0.4 | 3.5 | GO:2000659 | regulation of interleukin-1-mediated signaling pathway(GO:2000659) |
| 0.0 | 3.5 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
| 0.1 | 3.2 | GO:0010107 | potassium ion import(GO:0010107) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 5.4 | GO:0031528 | microvillus membrane(GO:0031528) |
| 0.0 | 4.1 | GO:0005814 | centriole(GO:0005814) |
| 0.0 | 4.0 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.1 | 3.0 | GO:0044217 | other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217) |
| 0.1 | 2.4 | GO:0042101 | T cell receptor complex(GO:0042101) |
| 0.2 | 2.3 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.0 | 2.2 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.2 | 2.1 | GO:0000138 | Golgi trans cisterna(GO:0000138) |
| 0.1 | 2.0 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
| 0.3 | 1.8 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 11.3 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
| 0.1 | 9.3 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.3 | 8.8 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.1 | 5.6 | GO:0043531 | ADP binding(GO:0043531) |
| 1.3 | 5.4 | GO:0005176 | ErbB-2 class receptor binding(GO:0005176) |
| 0.5 | 3.6 | GO:0008241 | peptidyl-dipeptidase activity(GO:0008241) |
| 0.4 | 3.6 | GO:0042834 | peptidoglycan binding(GO:0042834) |
| 0.0 | 3.3 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.1 | 3.1 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 0.5 | 3.0 | GO:0004028 | 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.8 | PID IL1 PATHWAY | IL1-mediated signaling events |
| 0.0 | 4.2 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 2.4 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 2.2 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.1 | 1.9 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.0 | 1.9 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.0 | 1.8 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 1.5 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.1 | 1.4 | ST G ALPHA S PATHWAY | G alpha s Pathway |
| 0.0 | 1.4 | PID CMYB PATHWAY | C-MYB transcription factor network |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 7.7 | REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.2 | 5.2 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.2 | 3.4 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.1 | 3.2 | REACTOME INWARDLY RECTIFYING K CHANNELS | Genes involved in Inwardly rectifying K+ channels |
| 0.1 | 2.7 | REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol |
| 0.1 | 2.7 | REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS | Genes involved in Phase 1 - Functionalization of compounds |
| 0.1 | 2.5 | REACTOME IL1 SIGNALING | Genes involved in Interleukin-1 signaling |
| 0.2 | 2.3 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
| 0.1 | 2.2 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 0.0 | 2.1 | REACTOME ASPARAGINE N LINKED GLYCOSYLATION | Genes involved in Asparagine N-linked glycosylation |