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avrg: 12D miR HR13_24
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Results for Figla
Z-value: 2.73
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Transcription factors associated with Figla
Network of associatons between targets according to the STRING database.
First level regulatory network of Figla
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 7.9 | GO:0060445 | branching involved in salivary gland morphogenesis(GO:0060445) |
| 0.6 | 6.4 | GO:0007342 | fusion of sperm to egg plasma membrane(GO:0007342) |
| 0.7 | 4.7 | GO:0035948 | positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) |
| 0.0 | 4.2 | GO:0015758 | glucose transport(GO:0015758) |
| 0.2 | 3.5 | GO:0048194 | Golgi vesicle budding(GO:0048194) |
| 1.1 | 3.4 | GO:1990535 | negative regulation of NAD(P)H oxidase activity(GO:0033861) neuron projection maintenance(GO:1990535) |
| 0.1 | 2.6 | GO:0010763 | positive regulation of fibroblast migration(GO:0010763) |
| 0.3 | 2.5 | GO:0035021 | negative regulation of Rac protein signal transduction(GO:0035021) |
| 0.2 | 2.4 | GO:0045198 | establishment of epithelial cell apical/basal polarity(GO:0045198) |
| 0.0 | 2.4 | GO:0016925 | protein sumoylation(GO:0016925) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.1 | 6.4 | GO:0034667 | integrin alpha3-beta1 complex(GO:0034667) |
| 0.1 | 3.4 | GO:0005732 | small nucleolar ribonucleoprotein complex(GO:0005732) |
| 0.0 | 3.2 | GO:0031985 | Golgi cisterna(GO:0031985) |
| 0.2 | 3.0 | GO:0044224 | juxtaparanode region of axon(GO:0044224) |
| 0.0 | 2.6 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
| 0.1 | 2.5 | GO:0036057 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.1 | 2.5 | GO:0045095 | keratin filament(GO:0045095) |
| 0.1 | 2.2 | GO:0005922 | connexon complex(GO:0005922) |
| 0.5 | 2.1 | GO:0005610 | laminin-5 complex(GO:0005610) |
| 0.1 | 2.1 | GO:0035102 | PRC1 complex(GO:0035102) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 12.4 | GO:0005179 | hormone activity(GO:0005179) |
| 0.0 | 8.7 | GO:0044822 | mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822) |
| 0.2 | 8.4 | GO:0001968 | fibronectin binding(GO:0001968) |
| 0.0 | 3.8 | GO:0030165 | PDZ domain binding(GO:0030165) |
| 0.0 | 3.6 | GO:0017124 | SH3 domain binding(GO:0017124) |
| 0.1 | 3.5 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
| 0.1 | 2.6 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
| 0.0 | 2.3 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.1 | 2.2 | GO:0005243 | gap junction channel activity(GO:0005243) |
| 0.1 | 2.1 | GO:0032183 | SUMO binding(GO:0032183) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 6.4 | PID INTEGRIN CS PATHWAY | Integrin family cell surface interactions |
| 0.1 | 4.7 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.1 | 2.6 | PID P38 ALPHA BETA PATHWAY | Regulation of p38-alpha and p38-beta |
| 0.0 | 2.0 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.0 | 1.7 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.0 | 1.4 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
| 0.0 | 1.4 | PID PI3KCI PATHWAY | Class I PI3K signaling events |
| 0.0 | 1.3 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
| 0.0 | 1.2 | PID ERBB1 INTERNALIZATION PATHWAY | Internalization of ErbB1 |
| 0.0 | 1.2 | PID TXA2PATHWAY | Thromboxane A2 receptor signaling |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 6.4 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |
| 0.1 | 5.4 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 0.3 | 4.7 | REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
| 0.0 | 4.4 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.1 | 2.2 | REACTOME GAP JUNCTION ASSEMBLY | Genes involved in Gap junction assembly |
| 0.0 | 2.1 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 0.0 | 1.9 | REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE | Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline |
| 0.0 | 1.8 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.0 | 1.8 | REACTOME NETRIN1 SIGNALING | Genes involved in Netrin-1 signaling |
| 0.0 | 1.5 | REACTOME NEPHRIN INTERACTIONS | Genes involved in Nephrin interactions |