ISMARA results: Irx4

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avrg: 12D miR HR13_24

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Results for Irx4

Z-value: 0.15

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Transcription factors associated with Irx4

Gene Symbol	Gene ID	Gene Info
Irx4 Ensembl NCBI MGI UniProt	ENSMUSG00000021604.9	Iroquois homeobox 4

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Irx4	mm10_v2_chr13_+_73260473_73260497	-0.29	4.0e-01	Click!

Activity profile of Irx4 motif

Sorted Z-values of Irx4 motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr2_+_24345305 Show fit	0.11	ENSMUST00000114482.1	Il1rn Ensembl NCBI MGI UniProt Show fit	interleukin 1 receptor antagonist
chr2_+_24345282 Show fit	0.09	ENSMUST00000114485.2	Il1rn Ensembl NCBI MGI UniProt Show fit	interleukin 1 receptor antagonist
chr1_+_45311538 Show fit	0.07	ENSMUST00000087883.6	Col3a1 Ensembl NCBI MGI UniProt Show fit	collagen, type III, alpha 1
chr11_-_11970540 Show fit	0.05	ENSMUST00000109653.1	Grb10 Ensembl NCBI MGI UniProt Show fit	growth factor receptor bound protein 10
chr8_+_84872105 Show fit	0.05	ENSMUST00000136026.1 ENSMUST00000170296.1	Syce2 Ensembl NCBI MGI UniProt Show fit	synaptonemal complex central element protein 2
chr6_-_83317589 Show fit	0.05	ENSMUST00000005810.6	Mthfd2 Ensembl NCBI MGI UniProt Show fit	methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase
chr17_-_27133902 Show fit	0.04	ENSMUST00000119227.1 ENSMUST00000025045.8	Uqcc2 Ensembl NCBI MGI UniProt Show fit	ubiquinol-cytochrome c reductase complex assembly factor 2
chr2_-_79908428 Show fit	0.03	ENSMUST00000102652.3 ENSMUST00000102651.3	Pde1a Ensembl NCBI MGI UniProt Show fit	phosphodiesterase 1A, calmodulin-dependent
chr15_-_35938186 Show fit	0.03	ENSMUST00000014457.8	Cox6c Ensembl NCBI MGI UniProt Show fit	cytochrome c oxidase subunit VIc
chr15_-_35938009 Show fit	0.02	ENSMUST00000156915.1	Cox6c Ensembl NCBI MGI UniProt Show fit	cytochrome c oxidase subunit VIc

Showing 1 to 10 of 18 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of Irx4

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.2	GO:2000660	negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0	0.1	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)

Showing 1 to 2 of 2 entries

Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0045352	interleukin-1, Type II receptor binding(GO:0005151) interleukin-1 receptor antagonist activity(GO:0005152) interleukin-1 Type I receptor antagonist activity(GO:0045352) interleukin-1 Type II receptor antagonist activity(GO:0045353)
0.0	0.0	GO:0004487	methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)

Showing 1 to 2 of 2 entries