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avrg: 12D miR HR13_24
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Results for Obox6_Obox5
Z-value: 2.42
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Transcription factors associated with Obox6_Obox5
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Obox6 | mm10_v2_chr7_-_15839678_15839678 | 0.31 | 3.6e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of Obox6_Obox5
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 5.9 | GO:0015015 | heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015) |
| 0.0 | 3.5 | GO:0008033 | tRNA processing(GO:0008033) |
| 1.1 | 3.2 | GO:0097155 | fasciculation of sensory neuron axon(GO:0097155) |
| 0.5 | 3.2 | GO:0051725 | protein de-ADP-ribosylation(GO:0051725) |
| 0.3 | 3.1 | GO:2000348 | regulation of CD40 signaling pathway(GO:2000348) |
| 0.1 | 2.8 | GO:0042775 | mitochondrial ATP synthesis coupled electron transport(GO:0042775) |
| 0.1 | 2.7 | GO:0021591 | ventricular system development(GO:0021591) |
| 0.5 | 2.6 | GO:0014016 | neuroblast differentiation(GO:0014016) |
| 0.8 | 2.4 | GO:0031660 | regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) |
| 0.1 | 2.0 | GO:0034472 | snRNA 3'-end processing(GO:0034472) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 4.3 | GO:0030061 | mitochondrial crista(GO:0030061) |
| 0.0 | 3.5 | GO:0005769 | early endosome(GO:0005769) |
| 0.2 | 2.9 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.1 | 2.5 | GO:0030964 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 0.6 | 2.4 | GO:0000942 | condensed nuclear chromosome outer kinetochore(GO:0000942) |
| 0.1 | 2.1 | GO:0032039 | integrator complex(GO:0032039) |
| 0.3 | 1.9 | GO:0005663 | DNA replication factor C complex(GO:0005663) |
| 0.2 | 1.9 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
| 0.0 | 1.8 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.0 | 1.8 | GO:0030018 | Z disc(GO:0030018) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.5 | 5.9 | GO:0017095 | heparan sulfate 6-O-sulfotransferase activity(GO:0017095) |
| 0.8 | 3.2 | GO:0003875 | ADP-ribosylarginine hydrolase activity(GO:0003875) |
| 0.4 | 3.2 | GO:0005004 | GPI-linked ephrin receptor activity(GO:0005004) |
| 0.1 | 2.8 | GO:0008137 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.6 | 2.6 | GO:0004104 | cholinesterase activity(GO:0004104) |
| 0.6 | 2.4 | GO:0061575 | cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575) |
| 0.1 | 2.1 | GO:0004000 | adenosine deaminase activity(GO:0004000) |
| 0.1 | 2.0 | GO:0070182 | DNA polymerase binding(GO:0070182) |
| 0.2 | 1.9 | GO:0033170 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
| 0.1 | 1.9 | GO:0070840 | dynein complex binding(GO:0070840) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 5.3 | PID BARD1 PATHWAY | BARD1 signaling events |
| 0.1 | 4.0 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 0.1 | 3.2 | PID EPHA FWDPATHWAY | EPHA forward signaling |
| 0.1 | 2.1 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.0 | 1.9 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.0 | 1.5 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.1 | 1.3 | PID THROMBIN PAR4 PATHWAY | PAR4-mediated thrombin signaling events |
| 0.0 | 1.3 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.0 | 1.1 | PID INTEGRIN A9B1 PATHWAY | Alpha9 beta1 integrin signaling events |
| 0.0 | 1.0 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 5.9 | REACTOME HS GAG BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.0 | 3.9 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
| 0.0 | 3.2 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 0.2 | 2.8 | REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER | Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER |
| 0.2 | 2.7 | REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
| 0.3 | 2.6 | REACTOME G2 M DNA DAMAGE CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
| 0.1 | 2.4 | REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY | Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery |
| 0.2 | 2.0 | REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY | Genes involved in Regulation of the Fanconi anemia pathway |
| 0.0 | 2.0 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.1 | 1.7 | REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC | Genes involved in Formation of tubulin folding intermediates by CCT/TriC |