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avrg: 12D miR HR13_24
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Results for Taf1
Z-value: 1.77
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Transcription factors associated with Taf1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Taf1 | mm10_v2_chrX_+_101532734_101532777 | 0.52 | 9.8e-02 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr2_+_119047116 Show fit | 1.94 |
ENSMUST00000152380.1
ENSMUST00000099542.2 |
cancer susceptibility candidate 5 |
|
| chr2_+_119047129 Show fit | 1.57 |
ENSMUST00000153300.1
ENSMUST00000028799.5 |
cancer susceptibility candidate 5 |
|
| chr2_+_30286406 Show fit | 1.21 |
ENSMUST00000138666.1
ENSMUST00000113634.2 |
nucleoporin 188 |
|
| chr9_+_122951051 Show fit | 1.10 |
ENSMUST00000040717.5
|
kinesin family member 15 |
|
| chr19_+_34922351 Show fit | 1.06 |
ENSMUST00000087341.5
|
kinesin family member 20B |
|
| chr3_+_69004711 Show fit | 1.04 |
ENSMUST00000042901.8
|
structural maintenance of chromosomes 4 |
|
| chr3_+_69004969 Show fit | 1.03 |
ENSMUST00000136502.1
ENSMUST00000107803.1 |
structural maintenance of chromosomes 4 |
|
| chr2_-_172370506 Show fit | 0.93 |
ENSMUST00000109139.1
ENSMUST00000028997.7 ENSMUST00000109140.3 |
aurora kinase A |
|
| chr12_-_108003594 Show fit | 0.91 |
ENSMUST00000066060.4
|
B cell leukemia/lymphoma 11B |
|
| chrX_-_73966329 Show fit | 0.90 |
ENSMUST00000114372.2
ENSMUST00000033761.6 |
host cell factor C1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Taf1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 2.1 | GO:0010032 | meiotic chromosome condensation(GO:0010032) |
| 0.4 | 2.0 | GO:0090521 | glomerular visceral epithelial cell migration(GO:0090521) |
| 0.6 | 1.8 | GO:0097534 | lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535) |
| 0.1 | 1.7 | GO:0000027 | ribosomal large subunit assembly(GO:0000027) |
| 0.3 | 1.5 | GO:0046952 | ketone body catabolic process(GO:0046952) |
| 0.2 | 1.5 | GO:0031126 | snoRNA 3'-end processing(GO:0031126) |
| 0.0 | 1.4 | GO:0000070 | mitotic sister chromatid segregation(GO:0000070) |
| 0.0 | 1.4 | GO:0042254 | ribosome biogenesis(GO:0042254) |
| 0.1 | 1.3 | GO:2000051 | negative regulation of non-canonical Wnt signaling pathway(GO:2000051) |
| 0.1 | 1.3 | GO:0000920 | cell separation after cytokinesis(GO:0000920) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.3 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
| 0.0 | 3.0 | GO:0015934 | large ribosomal subunit(GO:0015934) |
| 0.0 | 2.9 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.5 | 2.6 | GO:0044611 | nuclear pore inner ring(GO:0044611) |
| 0.2 | 2.1 | GO:0000796 | condensin complex(GO:0000796) |
| 0.1 | 2.0 | GO:0097431 | mitotic spindle pole(GO:0097431) |
| 0.1 | 1.7 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.2 | 1.5 | GO:0098536 | deuterosome(GO:0098536) |
| 0.0 | 1.5 | GO:0005763 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
| 0.0 | 1.5 | GO:0016605 | PML body(GO:0016605) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 7.8 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.0 | 3.8 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.1 | 3.0 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
| 0.0 | 2.1 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.4 | 1.5 | GO:0008260 | 3-oxoacid CoA-transferase activity(GO:0008260) |
| 0.0 | 1.5 | GO:0035064 | methylated histone binding(GO:0035064) |
| 0.1 | 1.2 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 0.0 | 1.1 | GO:0070182 | DNA polymerase binding(GO:0070182) |
| 0.1 | 1.0 | GO:0034513 | box H/ACA snoRNA binding(GO:0034513) |
| 0.1 | 1.0 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 5.9 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.0 | 1.6 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 0.0 | 1.4 | PID BARD1 PATHWAY | BARD1 signaling events |
| 0.0 | 0.9 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 0.0 | 0.9 | SA B CELL RECEPTOR COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
| 0.0 | 0.9 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.0 | 0.8 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.0 | 0.8 | PID ATM PATHWAY | ATM pathway |
| 0.0 | 0.6 | PID TCR RAS PATHWAY | Ras signaling in the CD4+ TCR pathway |
| 0.0 | 0.6 | ST GRANULE CELL SURVIVAL PATHWAY | Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway. |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 5.5 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.0 | 3.7 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
| 0.0 | 3.3 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.1 | 3.2 | REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY | Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery |
| 0.1 | 2.8 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.0 | 2.6 | REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 | Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 |
| 0.0 | 2.0 | REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS | Genes involved in CREB phosphorylation through the activation of Ras |
| 0.0 | 1.9 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 0.0 | 1.6 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 0.0 | 1.3 | REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM | Genes involved in Transport of Mature Transcript to Cytoplasm |