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Results for GMEB2

Z-value: 2.10

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Transcription factors associated with GMEB2

Gene Symbol Gene ID Gene Info
ENSDARG00000093240 si_ch73-302a13.2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GMEB2dr10_dc_chr23_-_41929027_41929077-0.774.9e-04Click!

Activity profile of GMEB2 motif

Sorted Z-values of GMEB2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of GMEB2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr9_-_25555313 7.67 ENSDART00000021672
enhancer of polycomb homolog 2 (Drosophila)
chr11_-_2437396 6.20

chr3_-_29779725 5.36 ENSDART00000151501
RUN domain containing 1
chr3_-_29779598 5.05 ENSDART00000151501
RUN domain containing 1
chr18_-_20684934 4.98 ENSDART00000005145
ankyrin repeat, SAM and basic leucine zipper domain containing 1
chr24_+_34183462 4.69 ENSDART00000143995
zgc:92591
chr23_-_35691369 4.56 ENSDART00000142369
major facilitator superfamily domain containing 5
chr2_-_17443607 4.32 ENSDART00000136207
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr9_-_25555345 4.21 ENSDART00000021672
enhancer of polycomb homolog 2 (Drosophila)
chr25_+_21001126 4.05 ENSDART00000079012
RAD52 homolog, DNA repair protein
chr12_-_28679813 3.80 ENSDART00000020667
oxysterol binding protein-like 7
chr2_-_17443642 3.66 ENSDART00000136207
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr10_+_29251234 3.64 ENSDART00000123033
phosphatidylinositol binding clathrin assembly protein a
chr24_+_34183557 3.62 ENSDART00000143995
zgc:92591
chr9_+_25109716 3.50 ENSDART00000037025
solute carrier family 39 (zinc transporter), member 10
chr15_+_5125138 3.45 ENSDART00000101937
phosphoglucomutase 2-like 1
chr4_+_18525469 3.28 ENSDART00000154154
ENSDARG00000097195
chr19_-_44459352 3.26 ENSDART00000151084
ubiquinol-cytochrome c reductase binding protein
chr11_-_2437361 3.21

chr7_-_37624410 3.18 ENSDART00000084282
PAP associated domain containing 5
chr4_+_9010972 3.18 ENSDART00000058007
sorting and assembly machinery component 50 homolog, like
chr13_+_36554762 3.14 ENSDART00000136030
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit s
chr3_-_29779552 3.14 ENSDART00000151501
RUN domain containing 1
chr15_+_5124897 3.12 ENSDART00000101937
phosphoglucomutase 2-like 1
chr5_-_23092592 3.12 ENSDART00000024815
family with sequence similarity 76, member B
chr7_-_37624329 3.09 ENSDART00000084282
PAP associated domain containing 5
chr15_+_5124690 3.07 ENSDART00000101937
phosphoglucomutase 2-like 1
chr9_-_25555518 2.99 ENSDART00000021672
enhancer of polycomb homolog 2 (Drosophila)
chr5_-_29818204 2.92 ENSDART00000098285
activating transcription factor 5a
chr18_-_14910497 2.89 ENSDART00000099701
selenoprotein O
chr18_-_20684687 2.86 ENSDART00000005145
ankyrin repeat, SAM and basic leucine zipper domain containing 1
chr11_-_36212977 2.84 ENSDART00000165203
ubiquitin specific peptidase 48
chr24_-_42053682 2.77 ENSDART00000169725
zinc finger and BTB domain containing 14
chr6_-_52677363 2.71 ENSDART00000083830
syndecan 4
chr10_+_16543480 2.64 ENSDART00000121864
solute carrier family 27 (fatty acid transporter), member 6
chr20_-_31840932 2.64 ENSDART00000137679
SAM and SH3 domain containing 1a
chr3_+_22204475 2.60 ENSDART00000055676
ENSDARG00000038186
chr24_-_23853204 2.60 ENSDART00000130053
zmp:0000000991
chr23_+_17596504 2.59 ENSDART00000002714
solute carrier family 17 (vesicular nucleotide transporter), member 9b
chr16_-_33864015 2.54

chr14_+_10319183 2.50 ENSDART00000136480
nucleoporin 62 like
chr16_-_5205600 2.47 ENSDART00000148955
branched chain keto acid dehydrogenase E1, beta polypeptide
chr13_+_42183685 2.47 ENSDART00000158367
insulin-degrading enzyme
chr13_+_29904945 2.46 ENSDART00000057525
DnaJ (Hsp40) homolog, subfamily B, member 12a
chr17_-_51729568 2.44 ENSDART00000157244
exonuclease 3'-5' domain containing 2
chr17_-_51729707 2.38 ENSDART00000157244
exonuclease 3'-5' domain containing 2
chr5_+_6005049 2.35

chr8_-_37989317 2.35 ENSDART00000067809
RAB11 family interacting protein 1 (class I) a
chr5_+_25538153 2.33 ENSDART00000010041
dihydrofolate reductase
chr23_+_38313746 2.31 ENSDART00000129593
zinc finger protein 217
chr11_+_11136919 2.30 ENSDART00000026135
lymphocyte antigen 75
chr1_+_48770997 2.28 ENSDART00000015007
TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr8_-_37989415 2.28 ENSDART00000067809
RAB11 family interacting protein 1 (class I) a
chr1_-_25369230 2.25 ENSDART00000171752
programmed cell death 4a
chr20_+_25587099 2.20 ENSDART00000063052
hook microtubule-tethering protein 1
chr7_+_13130111 2.18 ENSDART00000166318
diacylglycerol lipase, alpha
chr17_-_43409443 2.17 ENSDART00000156418
inositol-tetrakisphosphate 1-kinase b
chr6_-_23953873 2.15 ENSDART00000165697
ENSDARG00000098123
chr10_+_29251158 2.13 ENSDART00000123033
phosphatidylinositol binding clathrin assembly protein a
chr7_+_13130177 2.10 ENSDART00000166318
diacylglycerol lipase, alpha
chr21_+_6291936 2.02 ENSDART00000136539
si:ch211-225g23.1
chr8_+_30103357 1.99 ENSDART00000133717
Fanconi anemia, complementation group C
chr13_+_3807780 1.98 ENSDART00000012759
Yip1 domain family, member 3
chr17_-_25813136 1.96 ENSDART00000148743
hedgehog acyltransferase
chr7_+_41033439 1.96 ENSDART00000016660
ENSDARG00000016964
chr22_+_35229352 1.95 ENSDART00000061315
ENSDART00000146430
TSC22 domain family 2
chr13_+_42183490 1.91 ENSDART00000158367
insulin-degrading enzyme
chr20_-_38030337 1.91 ENSDART00000153451
angel homolog 2 (Drosophila)
chr7_+_69290790 1.88 ENSDART00000109507
Rap1 GTPase-GDP dissociation stimulator 1
chr20_+_54545050 1.87

chr7_-_23623141 1.85

KN150712v1_-_26150 1.82

chr25_+_21001016 1.81 ENSDART00000079012
RAD52 homolog, DNA repair protein
chr15_-_20476476 1.79 ENSDART00000008589
calcineurin-like EF-hand protein 2
chr6_-_10492724 1.73 ENSDART00000002247
Sp3b transcription factor
chr3_+_22204569 1.73 ENSDART00000055676
ENSDARG00000038186
chr20_-_9212139 1.71 ENSDART00000064140
YLP motif containing 1
chr17_-_36913302 1.70 ENSDART00000154981
SUMO1/sentrin specific peptidase 6b
chr15_+_5124616 1.70 ENSDART00000101937
phosphoglucomutase 2-like 1
chr16_+_14311427 1.68 ENSDART00000113679
death associated protein 3
chr12_+_17481598 1.68 ENSDART00000170449
ENSDART00000111565
PMS1 homolog 2, mismatch repair system component
chr15_+_5124820 1.67 ENSDART00000101937
phosphoglucomutase 2-like 1
chr25_+_21001338 1.66 ENSDART00000017488
RAD52 homolog, DNA repair protein
chr5_-_53748764 1.60 ENSDART00000160781
ENSDART00000160965
ENSDART00000161692
zinc finger, MYND-type containing 19
chr14_+_8641470 1.59 ENSDART00000158025
ribosomal protein S6 kinase a, like
chr18_-_14910429 1.59 ENSDART00000099701
selenoprotein O
chr13_+_29904913 1.57 ENSDART00000057525
DnaJ (Hsp40) homolog, subfamily B, member 12a
chr10_+_16543577 1.54 ENSDART00000121864
solute carrier family 27 (fatty acid transporter), member 6
chr17_+_16082983 1.49 ENSDART00000133154
zinc finger protein 395a
chr17_+_22050088 1.48

chr25_+_35540123 1.48 ENSDART00000126326
RPGRIP1-like
chr5_-_56539892 1.48

chr22_+_35229139 1.46 ENSDART00000061315
ENSDART00000146430
TSC22 domain family 2
chr5_+_56539999 1.46 ENSDART00000167660
praja ring finger 2
chr20_-_32502517 1.43 ENSDART00000153411
AFG1 like ATPase b
chr7_+_56423315 1.42

chr14_-_44794907 1.41 ENSDART00000172805
ENSDARG00000105401
chr1_+_22583970 1.39 ENSDART00000036448
lipoic acid synthetase
chr9_-_23431846 1.39 ENSDART00000053282
cyclin T2a
chr14_+_8641516 1.38 ENSDART00000158025
ribosomal protein S6 kinase a, like
chr13_-_36554590 1.38 ENSDART00000085298
L-2-hydroxyglutarate dehydrogenase
chr2_-_32502787 1.36 ENSDART00000110821
tetratricopeptide repeat domain 19
chr19_+_46667326 1.35 ENSDART00000158032
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1a (glutamate binding)
chr22_-_22277418 1.35 ENSDART00000111711
chromatin assembly factor 1, subunit A (p150)
chr22_-_22277386 1.35 ENSDART00000111711
chromatin assembly factor 1, subunit A (p150)
chr9_-_7676688 1.35 ENSDART00000102706
DnaJ (Hsp40) homolog, subfamily B, member 2
chr25_-_20968390 1.33 ENSDART00000109520
F-box and leucine-rich repeat protein 14a
chr20_+_25586940 1.28 ENSDART00000063052
hook microtubule-tethering protein 1
chr5_+_44054942 1.24 ENSDART00000136642
death-associated protein kinase 1
chr2_+_32842978 1.22 ENSDART00000143127
si:dkey-154p10.3
chr1_+_36593187 1.21 ENSDART00000171340
family with sequence similarity 193, member A
chr6_-_40457472 1.19 ENSDART00000103878
von Hippel-Lindau tumor suppressor
chr3_-_48458042 1.18 ENSDART00000156822
cell death-inducing p53 target 1
chr3_+_32802124 1.17 ENSDART00000112742
neighbor of brca1 gene 1b
chr12_-_28841710 1.16 ENSDART00000142933
zinc finger protein 646
chr3_+_32657833 1.15 ENSDART00000171895
TBC1 domain family, member 10b
chr21_+_1622040 1.10 ENSDART00000148540
ferrochelatase
chr1_-_25369054 1.10 ENSDART00000171752
programmed cell death 4a
chr19_-_12058542 1.06 ENSDART00000168308
si:ch73-49k18.1
chr16_+_41004516 1.06 ENSDART00000058587
glycogen synthase kinase binding protein
chr10_+_16544000 1.06 ENSDART00000121864
solute carrier family 27 (fatty acid transporter), member 6
chr11_+_43127567 1.04 ENSDART00000172982
solute carrier family 29 (equilibrative nucleoside transporter), member 1b
chr18_+_5303006 1.03

chr18_+_49253587 1.03 ENSDART00000059285
Yip1 interacting factor homolog B (S. cerevisiae)
chr23_+_38314255 1.00 ENSDART00000129593
zinc finger protein 217
chr12_+_20290791 0.97 ENSDART00000115015
Rho GTPase activating protein 17a
chr14_-_44794961 0.97 ENSDART00000172805
ENSDARG00000105401
chr16_+_40181425 0.93 ENSDART00000155421
centromere protein W
chr7_-_20378231 0.91

chr6_-_52677210 0.91 ENSDART00000083830
syndecan 4
chr8_-_1154220 0.91 ENSDART00000149969
ENSDART00000016800
zinc finger protein 367
chr6_-_51541332 0.89 ENSDART00000156336
ENSDART00000154512
si:dkey-6e2.2
chr16_+_14311271 0.87 ENSDART00000113679
death associated protein 3
chr17_-_6294655 0.87 ENSDART00000064700
fucosidase, alpha-L- 2, plasma
chr6_-_39905773 0.86 ENSDART00000148612
Ts translation elongation factor, mitochondrial
chr12_-_28841396 0.85

chr21_+_4345107 0.85 ENSDART00000025612
phytanoyl-CoA dioxygenase domain containing 1
chr13_+_3808095 0.83 ENSDART00000012759
Yip1 domain family, member 3
chr9_+_22846535 0.79 ENSDART00000101765
si:dkey-189g17.2
chr9_+_19719018 0.78 ENSDART00000129934
ENSDART00000125416
pbx/knotted 1 homeobox 1.1
chr18_-_14910358 0.78 ENSDART00000099701
selenoprotein O
chr19_+_40439263 0.76 ENSDART00000017359
splicing factor proline/glutamine-rich
chr20_-_9212089 0.75 ENSDART00000064140
YLP motif containing 1
chr1_+_5464124 0.74 ENSDART00000144559
cyclin Pas1/PHO80 domain containing 1
chr3_+_32801936 0.74 ENSDART00000112742
neighbor of brca1 gene 1b
chr17_-_5918853 0.74 ENSDART00000058890
ENSDART00000171084
epoxide hydrolase 2, cytoplasmic
chr8_-_30935167 0.72 ENSDART00000049944
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1a
chr8_+_20423036 0.72 ENSDART00000079618
REX1, RNA exonuclease 1 homolog
chr1_+_48770878 0.71 ENSDART00000015007
TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr25_-_20968316 0.69 ENSDART00000109520
F-box and leucine-rich repeat protein 14a
chr7_-_20378183 0.67

chr7_-_23623275 0.65 ENSDART00000123203
von Hippel-Lindau binding protein 1
chr6_+_8927621 0.63 ENSDART00000157552
zgc:112023
chr13_-_12353513 0.63 ENSDART00000134132
late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
chr20_+_38934332 0.62 ENSDART00000061334
intraflagellar transport 172
chr7_+_13130367 0.61 ENSDART00000166318
diacylglycerol lipase, alpha
chr14_+_10319051 0.60 ENSDART00000136480
nucleoporin 62 like
chr24_+_34183407 0.60 ENSDART00000143995
zgc:92591
chr14_+_8641354 0.59 ENSDART00000047993
ribosomal protein S6 kinase a, like
chr3_+_12966604 0.58 ENSDART00000172460
protein kinase cAMP-dependent type I regulatory subunit beta
chr16_-_30775394 0.56

chr16_+_20488737 0.55 ENSDART00000059619
FK506 binding protein 14
chr9_+_26029780 0.49 ENSDART00000127135
glycosyltransferase-like domain containing 1
chr9_+_23238634 0.48 ENSDART00000012478
methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
chr6_-_37767593 0.42 ENSDART00000078316
non imprinted in Prader-Willi/Angelman syndrome 2 (human)
chr6_-_6925121 0.42 ENSDART00000081760
Indian hedgehog homolog b
chr15_+_32940372 0.41 ENSDART00000170098
spastic paraplegia 20b (Troyer syndrome)
chr2_+_21431575 0.40 ENSDART00000109568
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha b
chr12_+_28841405 0.40 ENSDART00000033878
zinc finger protein 668
chr7_+_52486748 0.36 ENSDART00000111444
diphosphoinositol pentakisphosphate kinase 1a
chr25_-_28225408 0.36 ENSDART00000126490
formin binding protein 4
chr2_+_32843040 0.36 ENSDART00000143127
si:dkey-154p10.3
chr7_+_41033728 0.36 ENSDART00000016660
ENSDARG00000016964
chr16_-_20488542 0.35 ENSDART00000059623
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8
chr17_-_37247455 0.35 ENSDART00000108514
additional sex combs like transcriptional regulator 2
chr1_+_25110899 0.34 ENSDART00000129471
guanylate cyclase 1, soluble, beta 3
chr14_+_37205204 0.34 ENSDART00000173192
protocadherin 1b
chr13_+_3807844 0.32 ENSDART00000012759
Yip1 domain family, member 3
chr9_+_22008242 0.30 ENSDART00000136902
thioredoxin domain containing 9
chr2_-_42279072 0.27 ENSDART00000047055
tripartite motif containing 55a
chr25_-_6262259 0.27 ENSDART00000083539
SIN3 transcription regulator family member Aa
chr14_-_21635094 0.27 ENSDART00000054420
RAD9 checkpoint clamp component A
chr7_+_13130332 0.26 ENSDART00000166318
diacylglycerol lipase, alpha
chr24_+_5176362 0.23 ENSDART00000155926
si:ch73-206p6.1
chr16_-_21683623 0.23 ENSDART00000146914
membrane protein, palmitoylated 6a (MAGUK p55 subfamily member 6)
chr16_+_41065107 0.20 ENSDART00000058586
DEK proto-oncogene
chr5_-_23092453 0.16 ENSDART00000024815
family with sequence similarity 76, member B
chr12_+_11611780 0.15 ENSDART00000150191
WAPL cohesin release factor b
chr7_+_41033650 0.15 ENSDART00000016660
ENSDARG00000016964
KN150109v1_-_3702 0.15 ENSDART00000175695
ENSDARG00000107509
chr25_-_28225449 0.14 ENSDART00000126490
formin binding protein 4
chr7_-_67093071 0.11 ENSDART00000159408
proteasome 26S subunit, non-ATPase 7
chr20_-_36905932 0.08 ENSDART00000166966
solute carrier family 25, member 27
chr8_-_1154004 0.08 ENSDART00000149969
ENSDART00000016800
zinc finger protein 367
chr24_-_37596370 0.07 ENSDART00000162538
clusterin associated protein 1
chr12_-_3630622 0.07 ENSDART00000164707
cytochrome C oxidase assembly factor 3a
chr6_-_26905146 0.06 ENSDART00000011863
high density lipoprotein binding protein a
chr7_-_39480446 0.06 ENSDART00000016803
GrpE-like 1, mitochondrial
chr6_+_42478384 0.05 ENSDART00000084667
macrophage stimulating 1 receptor a
chr25_+_21001071 0.04 ENSDART00000079012
RAD52 homolog, DNA repair protein

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 7.6 GO:0045002 DNA recombinase assembly(GO:0000730) double-strand break repair via single-strand annealing(GO:0045002)
1.1 3.2 GO:0045040 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
1.0 5.1 GO:0099542 cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926) retrograde trans-synaptic signaling by lipid(GO:0098920) retrograde trans-synaptic signaling by endocannabinoid(GO:0098921) trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542)
0.9 3.6 GO:0036445 neuronal stem cell division(GO:0036445) somatic stem cell division(GO:0048103)
0.8 2.3 GO:0046655 folic acid metabolic process(GO:0046655)
0.7 8.0 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.6 14.9 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.6 5.3 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.6 7.8 GO:0034587 piRNA metabolic process(GO:0034587)
0.4 4.4 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.4 1.2 GO:0043576 respiratory gaseous exchange(GO:0007585) regulation of respiratory gaseous exchange(GO:0043576)
0.4 3.5 GO:0045022 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.4 1.5 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.3 3.6 GO:0042772 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.3 2.6 GO:0051382 kinetochore assembly(GO:0051382)
0.3 1.0 GO:0015862 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.2 0.9 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.2 1.4 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.2 1.9 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.2 4.0 GO:0071218 response to misfolded protein(GO:0051788) cellular response to misfolded protein(GO:0071218)
0.2 5.2 GO:0015908 fatty acid transport(GO:0015908)
0.2 1.9 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.2 13.0 GO:0006006 glucose metabolic process(GO:0006006)
0.1 1.5 GO:0046548 retinal rod cell development(GO:0046548)
0.1 1.3 GO:0007584 response to nutrient(GO:0007584)
0.1 0.4 GO:0070445 regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.1 1.5 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 1.4 GO:1902108 regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902108)
0.1 0.8 GO:0031061 negative regulation of histone methylation(GO:0031061)
0.1 3.0 GO:0043966 histone H3 acetylation(GO:0043966)
0.1 3.1 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.1 1.7 GO:0006298 mismatch repair(GO:0006298)
0.1 2.0 GO:0036297 interstrand cross-link repair(GO:0036297)
0.1 1.0 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.1 0.6 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 0.2 GO:0050857 regulation of antigen receptor-mediated signaling pathway(GO:0050854) regulation of B cell receptor signaling pathway(GO:0050855) positive regulation of antigen receptor-mediated signaling pathway(GO:0050857) positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 1.1 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.7 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.1 0.1 GO:0021551 central nervous system morphogenesis(GO:0021551)
0.0 4.3 GO:0015698 inorganic anion transport(GO:0015698)
0.0 0.4 GO:0006020 inositol metabolic process(GO:0006020)
0.0 2.0 GO:0018345 protein palmitoylation(GO:0018345)
0.0 3.9 GO:0045055 regulated exocytosis(GO:0045055)
0.0 0.8 GO:0032204 regulation of telomere maintenance(GO:0032204)
0.0 0.4 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.3 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 2.0 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.2 GO:0071922 regulation of sister chromatid cohesion(GO:0007063) regulation of cohesin loading(GO:0071922)
0.0 0.1 GO:0021547 midbrain-hindbrain boundary initiation(GO:0021547)
0.0 1.4 GO:0003341 cilium movement(GO:0003341)
0.0 2.6 GO:0001666 response to hypoxia(GO:0001666)
0.0 1.9 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.7 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.6 GO:0032008 positive regulation of TOR signaling(GO:0032008) response to amino acid(GO:0043200) cellular response to amino acid stimulus(GO:0071230)
0.0 2.8 GO:0006869 lipid transport(GO:0006869)
0.0 0.2 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 1.7 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.1 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 1.4 GO:0006633 fatty acid biosynthetic process(GO:0006633)
0.0 1.1 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.7 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 1.2 GO:0010942 positive regulation of cell death(GO:0010942) positive regulation of apoptotic process(GO:0043065) positive regulation of programmed cell death(GO:0043068)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 14.9 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
1.3 5.3 GO:0098894 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
1.1 7.8 GO:0071546 pi-body(GO:0071546)
0.9 4.4 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.7 3.5 GO:0070695 FHF complex(GO:0070695)
0.6 1.7 GO:0032389 MutLalpha complex(GO:0032389)
0.5 3.2 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.5 1.5 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.4 3.1 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.4 1.9 GO:0033186 CAF-1 complex(GO:0033186)
0.4 3.8 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.3 1.3 GO:0030062 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.2 2.0 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.2 1.9 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.2 8.0 GO:0005657 replication fork(GO:0005657)
0.1 3.0 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.1 1.2 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.1 1.2 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.1 2.6 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 8.9 GO:0000786 nucleosome(GO:0000786)
0.1 0.8 GO:0045171 intercellular bridge(GO:0045171)
0.1 0.6 GO:0071986 Ragulator complex(GO:0071986)
0.1 1.9 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 0.7 GO:0035060 brahma complex(GO:0035060)
0.1 5.1 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.6 GO:0016272 prefoldin complex(GO:0016272)
0.0 3.6 GO:0005925 focal adhesion(GO:0005925)
0.0 0.7 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.3 GO:0016580 Sin3 complex(GO:0016580)
0.0 2.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.6 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 2.4 GO:0016607 nuclear speck(GO:0016607)
0.0 0.3 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.9 GO:0000776 kinetochore(GO:0000776)
0.0 1.2 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 8.0 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.9 5.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.9 5.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.7 5.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.7 13.0 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.4 1.7 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.4 1.5 GO:0052725 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726)
0.3 14.9 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.3 3.6 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.3 4.0 GO:0030544 Hsp70 protein binding(GO:0030544)
0.2 3.5 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.2 3.8 GO:0015248 sterol transporter activity(GO:0015248)
0.2 0.7 GO:0016803 ether hydrolase activity(GO:0016803)
0.2 1.7 GO:0030983 mismatched DNA binding(GO:0030983)
0.2 1.4 GO:0016783 sulfurtransferase activity(GO:0016783)
0.1 3.6 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 1.2 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 3.1 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 7.0 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.1 0.4 GO:0033857 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 2.3 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.1 9.1 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 4.3 GO:0015103 inorganic anion transmembrane transporter activity(GO:0015103)
0.0 0.4 GO:0005113 patched binding(GO:0005113)
0.0 2.8 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 2.0 GO:0016409 palmitoyltransferase activity(GO:0016409)
0.0 4.5 GO:0008237 metallopeptidase activity(GO:0008237)
0.0 0.7 GO:0004527 exonuclease activity(GO:0004527)
0.0 1.9 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.7 GO:0036459 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 1.0 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.7 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.4 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 0.5 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 1.4 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors(GO:0016614)
0.0 0.9 GO:0042803 protein homodimerization activity(GO:0042803)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.9 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 5.1 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 2.0 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 7.0 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 2.6 PID TRAIL PATHWAY TRAIL signaling pathway
0.1 1.2 PID IFNG PATHWAY IFN-gamma pathway
0.1 1.2 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 2.0 PID BARD1 PATHWAY BARD1 signaling events
0.1 1.1 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.6 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.7 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.4 PID RAC1 REG PATHWAY Regulation of RAC1 activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 5.1 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.4 7.6 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.3 2.3 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.3 5.2 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.2 3.6 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.2 1.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 2.0 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 1.1 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.2 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 1.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.4 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.0 0.3 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.6 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.5 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport