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DANIO-CODE

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Results for LHX6

Z-value: 0.98

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Transcription factors associated with LHX6

Gene Symbol Gene ID Gene Info
LHX6
ENSDARG00000052165 si_ch211-236k19.2

Activity profile of LHX6 motif

Sorted Z-values of LHX6 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of LHX6

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr13_-_18564182 4.15 ENSDART00000176809
sfxn3
sideroflexin 3
chr17_-_45021393 3.19

chr12_+_47448318 2.45 ENSDART00000152857
fmn2b
formin 2b
chr10_-_34971985 2.38 ENSDART00000141201
ccna1
cyclin A1
chr22_+_37688839 2.30 ENSDART00000174664
ENSDART00000178200
FO704589.1
ENSDARG00000108910
chr24_+_19270877 2.29

chr5_+_37303599 1.99 ENSDART00000097754
ENSDART00000162470
tmprss4b
transmembrane protease, serine 4b
chr16_+_47283253 1.99 ENSDART00000062507
ica1
islet cell autoantigen 1
chr8_-_23759076 1.96 ENSDART00000145894
zgc:195245
zgc:195245
chr2_+_3115593 1.95 ENSDART00000160715
pik3r3a
phosphoinositide-3-kinase, regulatory subunit 3a (gamma)
chr3_+_17783319 1.80 ENSDART00000104299
cnp
2',3'-cyclic nucleotide 3' phosphodiesterase
chr9_+_18821640 1.79 ENSDART00000006514
gtf2f2b
general transcription factor IIF, polypeptide 2b
chr3_+_17562348 1.72

chr14_-_14353451 1.59 ENSDART00000170355
ENSDART00000159888
nsdhl
NAD(P) dependent steroid dehydrogenase-like
chr12_-_33256671 1.57 ENSDART00000066233
ENSDART00000148165
slc16a3
solute carrier family 16 (monocarboxylate transporter), member 3
chr11_-_44756789 1.53 ENSDART00000161712
syngr2b
synaptogyrin 2b
chr2_-_57020663 1.51

chr4_+_9466175 1.51 ENSDART00000012659
zgc:55888
zgc:55888
chr3_-_5157662 1.51 ENSDART00000169609
tefb
thyrotrophic embryonic factor b
chr4_+_4825461 1.49 ENSDART00000150309
ptprz1b
protein tyrosine phosphatase, receptor-type, Z polypeptide 1b
chr3_-_20912934 1.47 ENSDART00000156275
fam57ba
family with sequence similarity 57, member Ba
chr22_-_26254136 1.44 ENSDART00000060978
wdr83
WD repeat domain containing 83
chr6_+_28218420 1.42 ENSDART00000171216
ENSDART00000171377
si:ch73-14h10.2
si:ch73-14h10.2
chr13_-_37530793 1.41 ENSDART00000141295
si:dkey-188i13.11
si:dkey-188i13.11
chr18_-_43890836 1.38 ENSDART00000087382
ddx6
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr11_-_15886860 1.34 ENSDART00000170731
zgc:173544
zgc:173544
chr12_-_33256754 1.33 ENSDART00000066233
ENSDART00000148165
slc16a3
solute carrier family 16 (monocarboxylate transporter), member 3
chr6_-_46740359 1.32 ENSDART00000011970
zgc:66479
zgc:66479
chr16_+_47283374 1.29 ENSDART00000062507
ica1
islet cell autoantigen 1
KN150663v1_-_3381 1.29

chr12_-_22116694 1.25 ENSDART00000038310
ENSDART00000132731
ormdl3
ORMDL sphingolipid biosynthesis regulator 3
chr25_-_13394261 1.25 ENSDART00000056721
ldhd
lactate dehydrogenase D
chr19_-_4876806 1.24 ENSDART00000141336
ENSDART00000110551
st3gal1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr1_+_29919378 1.23 ENSDART00000127670
bora
bora, aurora kinase A activator
chr7_+_6918301 1.21 ENSDART00000109485
gal3st3
galactose-3-O-sulfotransferase 3
chr6_-_8125341 1.20 ENSDART00000139161
ENSDART00000140021
acp5a
acid phosphatase 5a, tartrate resistant
chr7_+_69290790 1.19 ENSDART00000109507
RAP1GDS1
Rap1 GTPase-GDP dissociation stimulator 1
chr17_+_7377230 1.17 ENSDART00000157123
shprh
SNF2 histone linker PHD RING helicase
chr23_+_43868027 1.17 ENSDART00000112598
ENSDART00000169576
otud4
OTU deubiquitinase 4
chr22_+_4035577 1.15 ENSDART00000170620
ctxn1
cortexin 1
chr12_-_1435708 1.12

chr18_-_14306241 1.11 ENSDART00000166643
mlycd
malonyl-CoA decarboxylase
chr17_+_52526741 1.10 ENSDART00000109891
angel1
angel homolog 1 (Drosophila)
chr5_-_39692560 1.09 ENSDART00000097525
snx18a
sorting nexin 18a
chr12_-_33257026 1.09 ENSDART00000066233
ENSDART00000148165
slc16a3
solute carrier family 16 (monocarboxylate transporter), member 3
chr16_+_42567707 1.09 ENSDART00000166640
si:ch211-215k15.5
si:ch211-215k15.5
chr19_-_12728868 1.08 ENSDART00000103692
fam210aa
family with sequence similarity 210, member Aa
chr13_+_12629211 1.08 ENSDART00000015127
zgc:100846
zgc:100846
chr8_+_11287550 1.07 ENSDART00000115057
tjp2b
tight junction protein 2b (zona occludens 2)
chr10_-_34971926 1.07 ENSDART00000141201
ccna1
cyclin A1
chr3_+_48607256 1.04 ENSDART00000168449
raver1
ribonucleoprotein, PTB-binding 1
chr2_+_6341404 1.04 ENSDART00000076700
zp3b
zona pellucida glycoprotein 3b
chr23_-_33692244 1.03

chr10_-_32550351 1.02 ENSDART00000129395
uvrag
UV radiation resistance associated gene
chr2_-_3115484 1.02

chr1_+_13244109 1.01 ENSDART00000157563
noctb
nocturnin b
chr12_-_33256934 1.01 ENSDART00000066233
ENSDART00000148165
slc16a3
solute carrier family 16 (monocarboxylate transporter), member 3
chr12_+_33257120 0.99

chr13_-_37530730 0.97 ENSDART00000141295
si:dkey-188i13.11
si:dkey-188i13.11
chr20_-_37910887 0.97 ENSDART00000147529
batf3
basic leucine zipper transcription factor, ATF-like 3
chr25_-_1243081 0.95 ENSDART00000156062
calml4b
calmodulin-like 4b
chr9_+_45193290 0.94 ENSDART00000176175
retsatl
retinol saturase (all-trans-retinol 13,14-reductase) like
chr13_+_8622628 0.92 ENSDART00000100241
haao
3-hydroxyanthranilate 3,4-dioxygenase
chr14_+_7596207 0.92 ENSDART00000113299
zgc:110843
zgc:110843
chr6_+_40925259 0.92 ENSDART00000002728
ENSDART00000145153
eif4enif1
eukaryotic translation initiation factor 4E nuclear import factor 1
KN149790v1_-_67669 0.92 ENSDART00000163561
ENSDARG00000099322
ENSDARG00000099322
chr12_-_33256599 0.91 ENSDART00000066233
ENSDART00000148165
slc16a3
solute carrier family 16 (monocarboxylate transporter), member 3
chr3_-_30754236 0.90 ENSDART00000109104
suv420h2
suppressor of variegation 4-20 homolog 2 (Drosophila)
chr24_+_17115897 0.90 ENSDART00000129554
bmi1a
bmi1 polycomb ring finger oncogene 1a
chr1_+_13244145 0.89 ENSDART00000157563
noctb
nocturnin b
chr7_+_22042296 0.89 ENSDART00000123457
TMEM102
transmembrane protein 102
chr22_-_21873054 0.88

chr17_+_22291644 0.85 ENSDART00000151929
ENSDART00000089919
ENSDART00000000804
slc8a1b
solute carrier family 8 (sodium/calcium exchanger), member 1b
chr14_-_14353487 0.85 ENSDART00000172241
nsdhl
NAD(P) dependent steroid dehydrogenase-like
chr7_+_6918384 0.84 ENSDART00000109485
gal3st3
galactose-3-O-sulfotransferase 3
chr3_-_7275821 0.84 ENSDART00000132197
BX005085.4
ENSDARG00000102658
chr3_+_26682186 0.83 ENSDART00000055537
socs1a
suppressor of cytokine signaling 1a
chr9_+_39309903 0.83

chr21_-_39521698 0.83 ENSDART00000020174
dynll2b
dynein, light chain, LC8-type 2b
chr8_-_14042703 0.81 ENSDART00000042867
dedd
death effector domain containing
chr5_+_60823823 0.80 ENSDART00000023676
bckdk
branched chain ketoacid dehydrogenase kinase
chr4_+_9466147 0.80 ENSDART00000012659
zgc:55888
zgc:55888
chr2_+_3115541 0.80 ENSDART00000160715
pik3r3a
phosphoinositide-3-kinase, regulatory subunit 3a (gamma)
chr12_+_23939869 0.80 ENSDART00000021298
asb3
ankyrin repeat and SOCS box containing 3
chr1_-_55195566 0.79 ENSDART00000019936
prkacab
protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b
chr16_-_28723759 0.79 ENSDART00000148456
abcb4
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr15_+_25503446 0.79 ENSDART00000154164
aifm4
apoptosis-inducing factor, mitochondrion-associated, 4
chr24_-_17261929 0.75 ENSDART00000153858
BX005392.2
ENSDARG00000096996
chr7_+_72925910 0.75 ENSDART00000175267
ENSDART00000179638
CABZ01067170.1
ENSDARG00000106453
chr18_-_26995562 0.74 ENSDART00000147823
rcn2
reticulocalbin 2
chr25_+_3169073 0.74

chr5_+_12894381 0.73 ENSDART00000051669
tctn2
tectonic family member 2
chr2_+_3115688 0.73 ENSDART00000160715
pik3r3a
phosphoinositide-3-kinase, regulatory subunit 3a (gamma)
chr23_-_31119917 0.73

chr7_+_20092235 0.72 ENSDART00000139274
ponzr1
plac8 onzin related protein 1
chr9_+_33310981 0.72

chr12_+_22459218 0.72 ENSDART00000171725
capgb
capping protein (actin filament), gelsolin-like b
chr22_-_22234380 0.72 ENSDART00000020937
hdgfrp2
hepatoma-derived growth factor-related protein 2
chr5_+_25133592 0.70 ENSDART00000098467
abhd17b
abhydrolase domain containing 17B
chr7_-_40359613 0.69 ENSDART00000173670
ube3c
ubiquitin protein ligase E3C
chr7_+_20091996 0.69 ENSDART00000138786
ponzr1
plac8 onzin related protein 1
chr25_-_10694465 0.69 ENSDART00000127054
BX572619.1
ENSDARG00000089303
chr5_+_60782855 0.67 ENSDART00000074073
alkbh4
alkB homolog 4, lysine demthylase
chr11_+_42310157 0.67 ENSDART00000085868
appl1
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
chr12_+_5013049 0.66 ENSDART00000161548
kif22
kinesin family member 22
chr5_+_55763413 0.65

chr23_+_37124543 0.64 ENSDART00000155706
CR762407.2
ENSDARG00000097111
chr22_-_20378023 0.64 ENSDART00000010048
map2k2a
mitogen-activated protein kinase kinase 2a
chr13_-_24695520 0.63 ENSDART00000142745
slka
STE20-like kinase a
chr21_+_4091665 0.63 ENSDART00000148138
lrrc8aa
leucine rich repeat containing 8 family, member Aa
chr4_-_75683584 0.63 ENSDART00000075770
zgc:162948
zgc:162948
chr10_-_25808063 0.62 ENSDART00000134176
postna
periostin, osteoblast specific factor a
chr12_+_22459177 0.61 ENSDART00000171725
capgb
capping protein (actin filament), gelsolin-like b
chr5_+_60823598 0.61 ENSDART00000023676
bckdk
branched chain ketoacid dehydrogenase kinase
chr25_+_20596490 0.61 ENSDART00000073648
kxd1
KxDL motif containing 1
chr12_-_1435616 0.60

chr3_-_26073798 0.59 ENSDART00000169123
gdpd3a
glycerophosphodiester phosphodiesterase domain containing 3a
chr6_-_8125287 0.59 ENSDART00000139161
ENSDART00000140021
acp5a
acid phosphatase 5a, tartrate resistant
chr3_-_27784565 0.59 ENSDART00000115370
mettl22
methyltransferase like 22
chr5_+_6005049 0.59

chr18_+_5707331 0.58

chr23_+_36494483 0.57 ENSDART00000042701
pip4k2ca
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma a
chr17_+_49540985 0.57

chr12_+_3632548 0.56

chr7_+_15059782 0.56 ENSDART00000165683
mespba
mesoderm posterior ba
chr21_-_39132507 0.56 ENSDART00000065143
unc119b
unc-119 homolog b (C. elegans)
chr10_+_16078021 0.55 ENSDART00000065037
ENSDART00000124502
lmnb1
lamin B1
chr3_+_12966604 0.55 ENSDART00000172460
PRKAR1B (1 of many)
protein kinase cAMP-dependent type I regulatory subunit beta
chr19_+_47918720 0.54 ENSDART00000157886
zgc:114119
zgc:114119
chr10_+_27028355 0.54 ENSDART00000064111
faub
Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed b
chr13_-_36537892 0.53 ENSDART00000085319
sos2
son of sevenless homolog 2 (Drosophila)
chr24_-_9838947 0.53 ENSDART00000138576
zgc:171977
zgc:171977
chr20_+_24047842 0.53 ENSDART00000128616
ENSDART00000144195
casp8ap2
caspase 8 associated protein 2
chr4_+_4825409 0.52 ENSDART00000150309
ptprz1b
protein tyrosine phosphatase, receptor-type, Z polypeptide 1b
chr10_+_34057791 0.51 ENSDART00000149934
kl
klotho
chr22_-_58352 0.51 ENSDART00000127829
atad3
ATPase family, AAA domain containing 3
chr4_+_76572863 0.50 ENSDART00000156692
arfgap3
ADP-ribosylation factor GTPase activating protein 3
chr2_+_42923652 0.50 ENSDART00000168318
BX005083.1
ENSDARG00000097562
chr12_+_23939934 0.49 ENSDART00000021298
asb3
ankyrin repeat and SOCS box containing 3
chr1_+_29919729 0.49 ENSDART00000127670
bora
bora, aurora kinase A activator
chr4_+_4825628 0.48 ENSDART00000150309
ptprz1b
protein tyrosine phosphatase, receptor-type, Z polypeptide 1b
chr25_+_3634007 0.48 ENSDART00000055845
thoc5
THO complex 5
chr5_+_37303707 0.48 ENSDART00000097754
ENSDART00000162470
tmprss4b
transmembrane protease, serine 4b
chr12_+_27498216 0.48 ENSDART00000066288
spata20
spermatogenesis associated 20
chr1_+_29919605 0.46 ENSDART00000127670
bora
bora, aurora kinase A activator
chr2_+_10209233 0.46 ENSDART00000160304
slc35a3b
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3b
chr1_-_54505112 0.45 ENSDART00000100619
ENSDART00000163796
LUC7L2
zgc:158803
chr3_+_32802899 0.45

chr5_-_39692410 0.44 ENSDART00000097525
snx18a
sorting nexin 18a
chr12_+_37039816 0.44 ENSDART00000162922
CR456627.1
ENSDARG00000104543
chr3_+_19829535 0.44

chr24_-_24578984 0.43 ENSDART00000012399
armc1
armadillo repeat containing 1
chr22_+_37696341 0.43 ENSDART00000007346
psmd1
proteasome 26S subunit, non-ATPase 1
chr6_+_50452131 0.43 ENSDART00000155051
mych
myelocytomatosis oncogene homolog
chr9_-_12623750 0.43 ENSDART00000142024
tra2b
transformer 2 beta homolog
chr13_+_12629243 0.43 ENSDART00000015127
zgc:100846
zgc:100846
chr6_+_58838038 0.42 ENSDART00000103144
ENSDART00000042595
dctn2
dynactin 2 (p50)
chr1_+_18740188 0.42 ENSDART00000144403
clockb
clock circadian regulator b
chr17_+_8054784 0.42 ENSDART00000133301
slc18b1
solute carrier family 18, subfamily B, member 1
chr7_+_72030256 0.42 ENSDART00000172021
tollip
toll interacting protein
chr12_+_35849423 0.41

chr14_+_21522672 0.41 ENSDART00000122739
ctbp1
C-terminal binding protein 1
chr19_+_12487051 0.41 ENSDART00000052238
ENSDART00000013865
seh1l
SEH1-like (S. cerevisiae)
chr2_-_36845638 0.41

chr24_-_36227144 0.41

chr3_-_30754325 0.41 ENSDART00000109104
suv420h2
suppressor of variegation 4-20 homolog 2 (Drosophila)
chr22_-_26254217 0.40 ENSDART00000060978
wdr83
WD repeat domain containing 83
chr22_-_22234212 0.40 ENSDART00000113824
ENSDART00000169594
ENSDART00000158261
hdgfrp2
hepatoma-derived growth factor-related protein 2
chr21_-_18238558 0.40 ENSDART00000126672
brd3a
bromodomain containing 3a
chr8_+_8908955 0.40 ENSDART00000131215
slc35a2
solute carrier family 35 (UDP-galactose transporter), member 2
chr21_-_13565401 0.40 ENSDART00000151547
pnpla7a
patatin-like phospholipase domain containing 7a
chr24_+_16402587 0.39 ENSDART00000164319
sema5a
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr3_+_32234155 0.39 ENSDART00000155967
ap2a1
adaptor-related protein complex 2, alpha 1 subunit
chr18_-_21961658 0.39 ENSDART00000043452
tsnaxip1
translin-associated factor X interacting protein 1
chr6_-_1685041 0.39

chr16_+_42567668 0.39 ENSDART00000166640
si:ch211-215k15.5
si:ch211-215k15.5
chr21_-_151444 0.38

chr23_+_38313746 0.37 ENSDART00000129593
znf217
zinc finger protein 217
chr1_-_22577855 0.37 ENSDART00000175685
rfc1
replication factor C (activator 1) 1
chr21_-_16442202 0.37

chr2_+_6341345 0.36 ENSDART00000058256
zp3b
zona pellucida glycoprotein 3b
chr24_+_37752868 0.36 ENSDART00000158181
wdr24
WD repeat domain 24
chr8_-_16428630 0.36 ENSDART00000098691
rnf11b
ring finger protein 11b
chr16_-_54679352 0.35 ENSDART00000083713
clk2b
CDC-like kinase 2b
chr22_-_21872864 0.34 ENSDART00000158501
gna11a
guanine nucleotide binding protein (G protein), alpha 11a (Gq class)
chr3_+_33788977 0.34 ENSDART00000055248
alkbh7
alkB homolog 7
chr13_-_36538099 0.33

chr25_-_2570515 0.33 ENSDART00000143721
adpgk
ADP-dependent glucokinase
chr6_+_18522756 0.32 ENSDART00000156169
ube2o
ubiquitin-conjugating enzyme E2O
chr16_-_28723722 0.32 ENSDART00000148456
abcb4
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr19_+_46371192 0.32 ENSDART00000169710
utp23
UTP23, small subunit (SSU) processome component, homolog (yeast)
chr14_-_11714513 0.31 ENSDART00000106654
znf711
zinc finger protein 711
chr19_+_9066225 0.30 ENSDART00000018973
scamp3
secretory carrier membrane protein 3
chr1_+_518777 0.30 ENSDART00000109083
txnl4b
thioredoxin-like 4B
chr5_+_32751876 0.30

chr24_+_26241878 0.29

chr2_-_2252088 0.29 ENSDART00000164674
ss18
synovial sarcoma translocation, chromosome 18 (H. sapiens)
chr5_-_21548930 0.29 ENSDART00000002938
mtmr8
myotubularin related protein 8
chr12_+_22459371 0.28 ENSDART00000171725
capgb
capping protein (actin filament), gelsolin-like b
chr13_-_48884956 0.28

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0090153 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.4 1.1 GO:2001293 malonyl-CoA metabolic process(GO:2001293)
0.3 0.9 GO:0043420 anthranilate metabolic process(GO:0043420)
0.3 1.2 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.3 0.8 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.3 1.8 GO:0045453 bone resorption(GO:0045453)
0.3 1.5 GO:0036268 swimming(GO:0036268)
0.2 3.5 GO:0043550 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.2 3.0 GO:0050796 regulation of insulin secretion(GO:0050796)
0.2 0.6 GO:1902635 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate metabolic process(GO:1902633) 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process(GO:1902635)
0.2 1.4 GO:0034063 stress granule assembly(GO:0034063)
0.2 0.5 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.2 0.8 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.2 1.8 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.2 1.4 GO:0072088 renal tubule morphogenesis(GO:0061333) nephron tubule morphogenesis(GO:0072078) nephron epithelium morphogenesis(GO:0072088)
0.1 0.6 GO:0097101 blood vessel endothelial cell fate specification(GO:0097101)
0.1 0.7 GO:0072584 caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.1 2.5 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 5.9 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.1 2.3 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.1 0.7 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.1 0.9 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.1 1.3 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.1 0.9 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1 1.4 GO:0035803 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1 0.4 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.1 1.1 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 1.6 GO:0051014 actin filament severing(GO:0051014)
0.1 2.6 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.1 3.7 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.1 4.2 GO:0006865 amino acid transport(GO:0006865)
0.1 0.7 GO:0070989 oxidative demethylation(GO:0070989)
0.1 0.7 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.1 1.5 GO:0071482 cellular response to light stimulus(GO:0071482)
0.1 0.3 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.2 GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
0.0 0.1 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.0 0.2 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.5 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.6 GO:0032418 lysosome localization(GO:0032418)
0.0 1.3 GO:0001878 response to yeast(GO:0001878)
0.0 1.4 GO:0010906 regulation of cellular carbohydrate metabolic process(GO:0010675) regulation of glucose metabolic process(GO:0010906)
0.0 0.7 GO:0001966 thigmotaxis(GO:0001966)
0.0 0.4 GO:0030719 P granule organization(GO:0030719)
0.0 0.3 GO:0097300 necrotic cell death(GO:0070265) programmed necrotic cell death(GO:0097300)
0.0 0.1 GO:0035264 multicellular organism growth(GO:0035264)
0.0 2.1 GO:0009247 glycolipid biosynthetic process(GO:0009247)
0.0 0.5 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.3 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.4 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 1.2 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.1 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.2 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.2 GO:0032467 positive regulation of cytokinesis(GO:0032467) mitotic cell cycle arrest(GO:0071850)
0.0 0.5 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0 1.2 GO:0072329 monocarboxylic acid catabolic process(GO:0072329)
0.0 1.1 GO:0045010 actin nucleation(GO:0045010)
0.0 0.5 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 0.4 GO:0010737 protein kinase A signaling(GO:0010737)
0.0 0.1 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.0 0.3 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.1 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.3 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 1.2 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.2 GO:0044030 regulation of DNA methylation(GO:0044030)
0.0 0.2 GO:0006415 translational termination(GO:0006415)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.5 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.4 1.8 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.4 1.3 GO:0035339 SPOTS complex(GO:0035339)
0.3 3.3 GO:0030667 secretory granule membrane(GO:0030667)
0.2 1.1 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 0.4 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.1 1.5 GO:0031594 neuromuscular junction(GO:0031594)
0.1 4.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 0.8 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 0.7 GO:0045171 intercellular bridge(GO:0045171)
0.1 0.7 GO:0070938 contractile ring(GO:0070938)
0.1 0.2 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.1 0.3 GO:0070985 TFIIK complex(GO:0070985)
0.1 0.9 GO:0045335 phagocytic vesicle(GO:0045335)
0.1 0.5 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 3.2 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.1 0.4 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.1 0.4 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.7 GO:0036038 MKS complex(GO:0036038)
0.0 0.6 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 1.4 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.2 GO:0071818 BAT3 complex(GO:0071818)
0.0 0.9 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.4 GO:0005869 dynactin complex(GO:0005869)
0.0 1.5 GO:0005776 autophagosome(GO:0005776)
0.0 1.6 GO:0001726 ruffle(GO:0001726)
0.0 0.3 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 1.3 GO:0005884 actin filament(GO:0005884)
0.0 0.5 GO:0016605 PML body(GO:0016605)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 1.0 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 1.2 GO:0000786 nucleosome(GO:0000786)
0.0 0.9 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.2 GO:0000792 heterochromatin(GO:0000792)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 5.9 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.6 4.2 GO:0022889 serine transmembrane transporter activity(GO:0022889)
0.5 2.1 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.4 1.2 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.4 1.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.3 2.4 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.3 1.4 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.2 2.0 GO:0008199 ferric iron binding(GO:0008199)
0.2 0.6 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.2 1.1 GO:0015562 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450) efflux transmembrane transporter activity(GO:0015562)
0.2 1.4 GO:0035804 structural constituent of egg coat(GO:0035804)
0.1 4.3 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 1.9 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 1.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 0.6 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 1.8 GO:0004112 cyclic-nucleotide phosphodiesterase activity(GO:0004112)
0.1 0.9 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 2.5 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.2 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 1.7 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 0.5 GO:0008422 beta-glucosidase activity(GO:0008422)
0.1 0.9 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.8 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 0.4 GO:0070888 E-box binding(GO:0070888)
0.1 0.9 GO:0008198 ferrous iron binding(GO:0008198)
0.1 0.4 GO:0004679 AMP-activated protein kinase activity(GO:0004679) cAMP-dependent protein kinase activity(GO:0004691)
0.1 1.1 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.1 3.5 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.1 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0 0.9 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.2 GO:0003979 UDP-glucose 6-dehydrogenase activity(GO:0003979)
0.0 0.7 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.3 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 1.1 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.3 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.9 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.2 GO:0001047 core promoter sequence-specific DNA binding(GO:0001046) core promoter binding(GO:0001047)
0.0 3.0 GO:0019904 protein domain specific binding(GO:0019904)
0.0 2.7 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.2 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 1.8 GO:0003678 DNA helicase activity(GO:0003678)
0.0 1.1 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 1.7 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 0.4 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 1.6 GO:0019901 protein kinase binding(GO:0019901)
0.0 0.1 GO:0043014 alpha-tubulin binding(GO:0043014)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.5 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 4.2 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 0.5 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 1.0 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 0.3 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 2.5 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.5 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.2 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.6 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.9 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.8 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.4 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.4 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.4 PID ATM PATHWAY ATM pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 5.9 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.2 1.2 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.2 3.7 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 0.5 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 0.9 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 1.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.4 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 0.8 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.2 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.7 REACTOME KINESINS Genes involved in Kinesins
0.0 0.5 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.0 0.6 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.2 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.4 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.4 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 1.1 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression