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DANIO-CODE

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Results for MAZ

Z-value: 6.68

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Transcription factors associated with MAZ

Gene Symbol Gene ID Gene Info
MAZ
ENSDARG00000063555 si_ch211-166g5.4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ENSDARG00000063555dr10_dc_chr12_-_3741925_37419660.902.0e-06Click!

Activity profile of MAZ motif

Sorted Z-values of MAZ motif

Network of associatons between targets according to the STRING database.

First level regulatory network of MAZ

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr2_-_44330405 25.35 ENSDART00000111246
cadm3
cell adhesion molecule 3
chr3_-_32202533 21.91 ENSDART00000155757
si:dkey-16p21.8
si:dkey-16p21.8
chr7_-_57796486 16.40 ENSDART00000043984
ank2b
ankyrin 2b, neuronal
chr7_-_60525749 14.89 ENSDART00000136999
pcxb
pyruvate carboxylase b
chr25_+_31769985 14.36

chr19_+_31046291 14.03 ENSDART00000052124
fam49al
family with sequence similarity 49, member A-like
chr7_+_25758469 13.95 ENSDART00000101126
alox12
arachidonate 12-lipoxygenase
chr7_+_39130411 13.50 ENSDART00000144750
tnni2b.1
troponin I type 2b (skeletal, fast), tandem duplicate 1
chr12_-_26760324 13.40 ENSDART00000047724
zeb1b
zinc finger E-box binding homeobox 1b
chr8_-_11191783 13.27 ENSDART00000131171
unc45b
unc-45 myosin chaperone B
chr19_-_19290260 13.25

chr10_+_10252074 13.24 ENSDART00000144214
sh2d3ca
SH2 domain containing 3Ca
chr23_-_35657313 12.33 ENSDART00000043429
jph2
junctophilin 2
chr14_+_30390575 12.18 ENSDART00000087884
ccdc85b
coiled-coil domain containing 85B
chr19_+_42491631 12.00 ENSDART00000150949
nfyc
nuclear transcription factor Y, gamma
chr7_+_44373815 11.82 ENSDART00000170721
si:dkey-56m19.5
si:dkey-56m19.5
chr24_+_13780640 11.60 ENSDART00000136443
ENSDART00000081595
ENSDART00000012253
eya1
EYA transcriptional coactivator and phosphatase 1
chr23_-_27226280 11.47 ENSDART00000141305
si:dkey-157g16.6
si:dkey-157g16.6
chr23_-_15807415 11.47 ENSDART00000178557
BX005011.3
ENSDARG00000108083
chr8_-_9081109 11.45 ENSDART00000176850
slc6a8
solute carrier family 6 (neurotransmitter transporter), member 8
chr7_+_34482282 11.40

chr13_-_36996246 11.36 ENSDART00000133242
syne2b
spectrin repeat containing, nuclear envelope 2b
chr20_+_14979154 11.31 ENSDART00000118157
dre-mir-199-1
dre-mir-199-1
chr24_+_26944182 11.30 ENSDART00000089541
dip2ca
disco-interacting protein 2 homolog Ca
chr3_+_26896869 11.29 ENSDART00000065495
emp2
epithelial membrane protein 2
chr19_-_46396376 11.18

chr4_-_17066886 10.98 ENSDART00000134595
sox5
SRY (sex determining region Y)-box 5
chr19_-_6384776 10.93

chr16_+_23516127 10.60 ENSDART00000004679
icn
ictacalcin
chr3_+_53518347 10.46 ENSDART00000170461
col5a3a
collagen, type V, alpha 3a
chr14_-_9216303 10.44 ENSDART00000054689
atoh8
atonal bHLH transcription factor 8
chr20_-_21773202 10.36 ENSDART00000133286
si:ch211-207i1.2
si:ch211-207i1.2
chr14_-_25279835 10.28 ENSDART00000163669
cplx2
complexin 2
chr11_-_29316162 10.27 ENSDART00000163958
arhgef10la
Rho guanine nucleotide exchange factor (GEF) 10-like a
chr11_-_32461160 10.26 ENSDART00000155592
pcdh17
protocadherin 17
chr10_+_31358236 10.25 ENSDART00000145562
robo4
roundabout, axon guidance receptor, homolog 4 (Drosophila)
chr24_-_4941954 10.23 ENSDART00000127597
zic1
zic family member 1 (odd-paired homolog, Drosophila)
chr21_-_11554253 10.23 ENSDART00000133443
cast
calpastatin
chr1_-_37990863 10.17 ENSDART00000132402
gpm6ab
glycoprotein M6Ab
chr6_+_37881015 10.14 ENSDART00000087311
oca2
oculocutaneous albinism II
chr3_-_60929921 9.97 ENSDART00000055064
pvalb8
parvalbumin 8
chr7_+_21455138 9.97 ENSDART00000173992
kdm6ba
lysine (K)-specific demethylase 6B, a
chr19_-_2399429 9.88 ENSDART00000043595
twist1a
twist family bHLH transcription factor 1a
chr2_-_4277516 9.86

chr20_+_22321303 9.86 ENSDART00000049204
kdr
kinase insert domain receptor (a type III receptor tyrosine kinase)
chr4_-_12863235 9.79 ENSDART00000080536
hmga2
high mobility group AT-hook 2
chr17_+_48999061 9.78 ENSDART00000177390
tiam2a
T-cell lymphoma invasion and metastasis 2a
KN149946v1_-_12861 9.78 ENSDART00000163016
CABZ01048402.2
ENSDARG00000103875
chr11_-_25592102 9.77 ENSDART00000103549
skib
v-ski avian sarcoma viral oncogene homolog b
chr18_-_45750 9.66 ENSDART00000148821
gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr21_-_43020159 9.61 ENSDART00000065097
dpysl3
dihydropyrimidinase-like 3
chr5_-_13826859 9.59 ENSDART00000137355
tet3
tet methylcytosine dioxygenase 3
chr19_-_5338129 9.58 ENSDART00000081951
stx1b
syntaxin 1B
chr4_-_9172622 9.53 ENSDART00000042963
chst11
carbohydrate (chondroitin 4) sulfotransferase 11
chr10_+_10252239 9.44 ENSDART00000144214
sh2d3ca
SH2 domain containing 3Ca
chr7_+_20699191 9.41 ENSDART00000062003
efnb3b
ephrin-B3b
chr7_+_35769973 9.38 ENSDART00000168658
irx3a
iroquois homeobox 3a
chr2_-_39710140 9.34 ENSDART00000147821
spsb4a
splA/ryanodine receptor domain and SOCS box containing 4a
chr8_+_28493742 9.26 ENSDART00000053782
scrt2
scratch family zinc finger 2
chr18_-_39602605 9.20 ENSDART00000125116
tnfaip8l3
tumor necrosis factor, alpha-induced protein 8-like 3
chr20_-_54192057 9.19 ENSDART00000023550
hsp90aa1.2
heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2
chr19_+_4996328 9.07 ENSDART00000165082
ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr18_-_11216447 9.02 ENSDART00000040500
tspan9a
tetraspanin 9a
chr4_+_11312432 8.88 ENSDART00000051792
sema3aa
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Aa
chr20_-_29580624 8.83 ENSDART00000062370
actc1a
actin, alpha, cardiac muscle 1a
chr9_+_14180954 8.81 ENSDART00000148055
si:ch211-67e16.11
si:ch211-67e16.11
chr8_-_52952226 8.79 ENSDART00000168185
nr6a1a
nuclear receptor subfamily 6, group A, member 1a
chr7_-_23965038 8.70 ENSDART00000010124
slc7a8a
solute carrier family 7 (amino acid transporter light chain, L system), member 8a
chr3_-_38550961 8.65 ENSDART00000155042
mpp3a
membrane protein, palmitoylated 3a (MAGUK p55 subfamily member 3)
chr5_+_4372660 8.64 ENSDART00000067599
angptl2a
angiopoietin-like 2a
chr14_+_21531709 8.64 ENSDART00000144367
ctbp1
C-terminal binding protein 1
chr25_-_2485276 8.63 ENSDART00000154889
ENSDART00000155027
BX957346.1
ENSDARG00000096850
chr7_-_71958596 8.61

chr9_+_54688205 8.53 ENSDART00000067544
egfl6
EGF-like-domain, multiple 6
chr7_-_41188744 8.50 ENSDART00000174087
smarcd3b
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3b
chr3_+_32293441 8.45 ENSDART00000156464
prr12b
proline rich 12b
chr17_+_52736192 8.45 ENSDART00000158273
ENSDART00000161414
meis2a
Meis homeobox 2a
chr23_-_31502149 8.38 ENSDART00000053545
zgc:153284
zgc:153284
chr7_-_52283383 8.38 ENSDART00000165649
tcf12
transcription factor 12
chr19_-_5142310 8.35 ENSDART00000130062
chd4a
chromodomain helicase DNA binding protein 4a
chr2_+_23038657 8.27 ENSDART00000089012
kif1ab
kinesin family member 1Ab
chr8_+_39964695 8.22 ENSDART00000073782
ggt5a
gamma-glutamyltransferase 5a
chr17_+_22359660 8.21 ENSDART00000162670
slc8a1b
solute carrier family 8 (sodium/calcium exchanger), member 1b
chr2_+_43619752 8.14 ENSDART00000142078
ENSDART00000098265
ENSDART00000098267
nrp1b
neuropilin 1b
chr20_+_30917073 8.13

chr23_-_27226387 8.11 ENSDART00000141305
si:dkey-157g16.6
si:dkey-157g16.6
chr13_-_49826330 8.10 ENSDART00000099475
nid1a
nidogen 1a
chr18_+_44656323 8.10 ENSDART00000059063
ehd2b
EH-domain containing 2b
chr16_-_51390400 8.03 ENSDART00000148894
serpinb14
serpin peptidase inhibitor, clade B (ovalbumin), member 14
chr14_+_23986703 7.96 ENSDART00000079164
klhl3
kelch-like family member 3
chr19_+_9113356 7.93 ENSDART00000127755
ash1l
ash1 (absent, small, or homeotic)-like (Drosophila)
chr11_-_25592017 7.91 ENSDART00000103549
skib
v-ski avian sarcoma viral oncogene homolog b
chr20_+_26408687 7.89

chr13_-_508202 7.86 ENSDART00000066080
ENSDART00000128969
slit1a
slit homolog 1a (Drosophila)
chr19_+_42492029 7.85 ENSDART00000150949
nfyc
nuclear transcription factor Y, gamma
chr18_+_12207888 7.82

chr22_-_95158 7.77

chr19_-_47994946 7.76 ENSDART00000114549
CU695215.1
ENSDARG00000076126
chr16_+_23172295 7.71 ENSDART00000167518
ENSDART00000161087
efna3b
ephrin-A3b
chr16_-_37461878 7.69 ENSDART00000142916
si:ch211-208k15.1
si:ch211-208k15.1
chr3_-_24925189 7.68 ENSDART00000156459
ep300b
E1A binding protein p300 b
chr20_-_26521700 7.65 ENSDART00000110883
akap12b
A kinase (PRKA) anchor protein 12b
chr24_+_28364360 7.64 ENSDART00000018037
arhgap29a
Rho GTPase activating protein 29a
chr7_-_7164950 7.63 ENSDART00000012637
zgc:101810
zgc:101810
chr6_+_2849460 7.60

chr19_-_2011177 7.55 ENSDART00000108784
mturn
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr1_-_18709814 7.55 ENSDART00000145224
rbm47
RNA binding motif protein 47
chr10_-_31619761 7.43 ENSDART00000023575
robo3
roundabout, axon guidance receptor, homolog 3 (Drosophila)
chr4_-_12862869 7.36 ENSDART00000080536
hmga2
high mobility group AT-hook 2
chr5_-_47520995 7.25 ENSDART00000144252
BX465834.1
ENSDARG00000095715
chr21_+_26660833 7.22 ENSDART00000004109
gng3
guanine nucleotide binding protein (G protein), gamma 3
chr13_-_31304614 7.19

chr13_-_14978365 7.19

chr14_+_34146377 7.15 ENSDART00000131861
tmsb2
thymosin beta 2
chr18_+_22367874 7.13

KN149987v1_-_29629 7.08 ENSDART00000159555
ENSDART00000168161
ENSDARG00000103311
ENSDARG00000103311
chr24_-_25283218 7.03 ENSDART00000090010
phex
phosphate regulating endopeptidase homolog, X-linked
chr11_-_25803101 7.03 ENSDART00000088888
kaznb
kazrin, periplakin interacting protein b
chr15_-_2224784 6.97 ENSDART00000009564
shox2
short stature homeobox 2
chr6_+_55355763 6.94 ENSDART00000169240
pltp
phospholipid transfer protein
chr2_-_32572545 6.92 ENSDART00000056641
smarcd3a
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3a
chr25_+_30746445 6.91 ENSDART00000156916
lsp1
lymphocyte-specific protein 1
chr23_-_9924987 6.90 ENSDART00000005015
prkcbp1l
protein kinase C binding protein 1, like
chr12_-_10372055 6.87 ENSDART00000052001
eef2k
eukaryotic elongation factor 2 kinase
chr17_+_48999102 6.86 ENSDART00000177390
tiam2a
T-cell lymphoma invasion and metastasis 2a
chr17_-_52735615 6.80

chr16_-_51390484 6.79 ENSDART00000148894
serpinb14
serpin peptidase inhibitor, clade B (ovalbumin), member 14
chr8_-_23102555 6.79

chr17_-_44133941 6.75 ENSDART00000126097
otx2
orthodenticle homeobox 2
chr13_+_22350043 6.74 ENSDART00000136863
ldb3a
LIM domain binding 3a
chr5_+_37662896 6.73 ENSDART00000051231
gnb2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr1_-_50831155 6.73 ENSDART00000152719
spred2a
sprouty-related, EVH1 domain containing 2a
chr16_-_12579115 6.69 ENSDART00000147483
ephb6
eph receptor B6
chr3_+_17210396 6.65 ENSDART00000090676
si:ch211-210g13.5
si:ch211-210g13.5
chr15_-_23407388 6.58 ENSDART00000020425
mcamb
melanoma cell adhesion molecule b
chr22_-_21021645 6.57 ENSDART00000133982
ssbp4
single stranded DNA binding protein 4
chr9_-_49834232 6.56

chr16_+_25845432 6.51

chr15_+_19902697 6.51 ENSDART00000101204
alcamb
activated leukocyte cell adhesion molecule b
chr12_+_29994735 6.45 ENSDART00000042572
ENSDART00000153025
ablim1b
actin binding LIM protein 1b
chr11_+_23695123 6.44 ENSDART00000000486
cntn2
contactin 2
chr13_-_219661 6.40 ENSDART00000133731
si:ch1073-291c23.2
si:ch1073-291c23.2
chr21_-_25567978 6.39 ENSDART00000133134
efemp2b
EGF containing fibulin-like extracellular matrix protein 2b
chr18_-_47890567 6.34

chr20_+_15119519 6.32 ENSDART00000039345
myoc
myocilin
chr16_+_5466342 6.32 ENSDART00000160008
plecb
plectin b
chr2_-_9848848 6.29 ENSDART00000056901
zgc:153615
zgc:153615
chr3_-_60930025 6.28 ENSDART00000055064
pvalb8
parvalbumin 8
chr4_-_24310846 6.27 ENSDART00000017443
celf2
cugbp, Elav-like family member 2
chr13_-_18704185 6.27 ENSDART00000146795
lzts2a
leucine zipper, putative tumor suppressor 2a
chr25_-_4376129 6.26

chr5_-_13844114 6.23

chr11_-_11534819 6.21 ENSDART00000104254
krt15
keratin 15
chr24_+_19374200 6.17 ENSDART00000056081
ENSDART00000027022
sulf1
sulfatase 1
chr20_-_47123598 6.13 ENSDART00000100320
dnmt3aa
DNA (cytosine-5-)-methyltransferase 3 alpha a
chr20_+_15119754 6.11 ENSDART00000039345
myoc
myocilin
chr4_+_14361566 6.08 ENSDART00000007103
nuak1a
NUAK family, SNF1-like kinase, 1a
chr11_-_23226859 6.08 ENSDART00000159221
plekha6
pleckstrin homology domain containing, family A member 6
chr11_-_1792616 6.08

chr23_+_6298911 6.06 ENSDART00000139795
syt2a
synaptotagmin IIa
chr1_-_51862897 6.05 ENSDART00000136469
acy3.2
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr7_+_19300351 6.05 ENSDART00000169060
si:ch211-212k18.5
si:ch211-212k18.5
chr10_-_22834248 6.00 ENSDART00000079469
pcolcea
procollagen C-endopeptidase enhancer a
chr21_-_37509454 6.00 ENSDART00000175126
fgfr4
fibroblast growth factor receptor 4
chr25_+_558191 5.93 ENSDART00000126863
ENSDART00000166012
nell2a
neural EGFL like 2a
chr20_+_316191 5.91 ENSDART00000104807
si:dkey-119m7.4
si:dkey-119m7.4
chr11_-_37921642 5.85

chr20_+_35377079 5.83 ENSDART00000168216
fam49a
family with sequence similarity 49, member A
chr5_-_13826795 5.82 ENSDART00000137355
tet3
tet methylcytosine dioxygenase 3
chr19_-_27807312 5.82

chr6_+_37880936 5.82 ENSDART00000087311
oca2
oculocutaneous albinism II
chr11_-_21143897 5.78 ENSDART00000163008
RASSF5
Ras association domain family member 5
chr5_+_6054781 5.78 ENSDART00000060532
zgc:110796
zgc:110796
chr1_-_28241500 5.75 ENSDART00000019770
gpm6ba
glycoprotein M6Ba
chr15_-_20088439 5.73 ENSDART00000161379
auts2b
autism susceptibility candidate 2b
chr7_-_71638662 5.73 ENSDART00000162984
cacnb2a
calcium channel, voltage-dependent, beta 2a
chr20_+_6640497 5.73 ENSDART00000138361
tns3.2
tensin 3, tandem duplicate 2
chr15_-_17074348 5.67 ENSDART00000156768
hip1
huntingtin interacting protein 1
chr23_+_34079219 5.67 ENSDART00000132668
si:ch211-207e14.4
si:ch211-207e14.4
chr6_-_39278328 5.65 ENSDART00000148531
arhgef25b
Rho guanine nucleotide exchange factor (GEF) 25b
chr3_-_20888014 5.65 ENSDART00000002393
rundc3aa
RUN domain containing 3Aa
chr20_+_30910294 5.64

chr19_+_42491275 5.64

chr14_+_34207218 5.61 ENSDART00000135608
gabrp
gamma-aminobutyric acid (GABA) A receptor, pi
chr1_-_22144014 5.60 ENSDART00000043556
ldb2b
LIM domain binding 2b
chr12_+_47450923 5.59 ENSDART00000105328
fmn2b
formin 2b
chr5_+_8843643 5.57 ENSDART00000149417
ENSDART00000061616
tal2
T-cell acute lymphocytic leukemia 2
chr14_+_45895103 5.57

chr18_-_45892 5.57 ENSDART00000052641
gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr24_-_34449257 5.56 ENSDART00000128690
agap3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr8_+_22910147 5.54 ENSDART00000063096
sypa
synaptophysin a
chr10_+_22759607 5.52

chr14_-_6901415 5.48 ENSDART00000167994
ENSDART00000166532
stox2b
storkhead box 2b
chr18_+_21133694 5.47 ENSDART00000060015
chka
choline kinase alpha
chr18_+_45680282 5.45 ENSDART00000109948
qser1
glutamine and serine rich 1
chr20_+_23392782 5.45

chr24_-_11327087 5.44 ENSDART00000082264
pxdc1b
PX domain containing 1b
chr18_-_3741790 5.44

chr2_-_43318809 5.43 ENSDART00000132588
crema
cAMP responsive element modulator a
chr20_+_33972327 5.42 ENSDART00000170930
rxrgb
retinoid X receptor, gamma b

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.1 15.4 GO:0032616 interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)
5.1 15.2 GO:0006601 creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
4.5 13.4 GO:0070587 regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
4.3 21.3 GO:0036371 protein localization to T-tubule(GO:0036371)
3.5 14.0 GO:0019372 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
3.2 9.6 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
3.0 8.9 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582) axon regeneration at neuromuscular junction(GO:0014814) positive regulation of synaptic growth at neuromuscular junction(GO:0045887) positive regulation of neuromuscular junction development(GO:1904398)
2.8 11.3 GO:0048677 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
2.8 11.1 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
2.7 16.0 GO:0042438 melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438)
2.6 10.4 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
2.5 7.5 GO:2001017 regulation of retrograde axon cargo transport(GO:2001017)
2.3 6.9 GO:0050810 regulation of steroid biosynthetic process(GO:0050810)
2.3 9.1 GO:0006751 glutathione catabolic process(GO:0006751)
2.3 22.7 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
2.2 8.7 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910)
2.0 10.2 GO:0048853 forebrain morphogenesis(GO:0048853)
2.0 8.1 GO:0035767 endothelial cell chemotaxis(GO:0035767)
2.0 22.2 GO:0006337 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
2.0 8.0 GO:0070293 renal absorption(GO:0070293)
1.9 11.6 GO:0016576 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
1.9 9.6 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
1.9 5.7 GO:0010752 regulation of cGMP-mediated signaling(GO:0010752)
1.9 7.4 GO:0016199 axon midline choice point recognition(GO:0016199)
1.8 9.2 GO:0046677 response to antibiotic(GO:0046677)
1.8 16.2 GO:0050936 xanthophore differentiation(GO:0050936)
1.8 5.4 GO:0098810 neurotransmitter uptake(GO:0001504) regulation of neurotransmitter uptake(GO:0051580) neurotransmitter reuptake(GO:0098810)
1.8 8.9 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
1.8 8.8 GO:0003197 endocardial cushion development(GO:0003197)
1.7 6.9 GO:0034368 protein-lipid complex remodeling(GO:0034368) plasma lipoprotein particle remodeling(GO:0034369)
1.7 16.6 GO:0051489 regulation of filopodium assembly(GO:0051489)
1.6 6.3 GO:0035332 positive regulation of hippo signaling(GO:0035332)
1.6 26.6 GO:0051492 regulation of stress fiber assembly(GO:0051492)
1.5 10.8 GO:0001964 startle response(GO:0001964)
1.5 7.5 GO:0045639 positive regulation of myeloid cell differentiation(GO:0045639)
1.5 4.5 GO:0001955 blood vessel maturation(GO:0001955)
1.5 17.8 GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043516)
1.4 11.3 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
1.4 9.7 GO:0030104 water homeostasis(GO:0030104)
1.4 11.1 GO:0071557 histone H3-K27 demethylation(GO:0071557)
1.4 4.2 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
1.4 4.1 GO:0060898 eye field cell fate commitment involved in camera-type eye formation(GO:0060898)
1.3 4.0 GO:0072488 ammonium transmembrane transport(GO:0072488)
1.3 6.4 GO:0048251 elastic fiber assembly(GO:0048251)
1.3 7.5 GO:2000742 regulation of anterior head development(GO:2000742)
1.2 14.7 GO:0046686 response to cadmium ion(GO:0046686)
1.2 21.9 GO:0006825 copper ion transport(GO:0006825)
1.2 7.2 GO:0042989 sequestering of actin monomers(GO:0042989)
1.2 7.1 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
1.1 11.4 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
1.1 10.2 GO:0097341 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
1.1 4.4 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
1.1 3.3 GO:0071300 cellular response to retinoic acid(GO:0071300)
1.0 2.9 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154)
0.9 8.5 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.9 6.5 GO:0021885 forebrain cell migration(GO:0021885)
0.9 20.4 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.9 5.3 GO:0006703 estrogen biosynthetic process(GO:0006703) estrogen metabolic process(GO:0008210)
0.9 9.6 GO:1901797 negative regulation of signal transduction by p53 class mediator(GO:1901797) negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902254)
0.9 4.3 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.8 24.5 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.8 2.5 GO:0045217 cell-cell junction maintenance(GO:0045217)
0.8 8.2 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.8 16.9 GO:0030199 collagen fibril organization(GO:0030199)
0.8 9.6 GO:0061300 cerebellum vasculature development(GO:0061300)
0.8 6.3 GO:0051013 microtubule severing(GO:0051013)
0.8 3.1 GO:0030220 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.8 2.3 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.7 5.1 GO:2001044 regulation of integrin-mediated signaling pathway(GO:2001044) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.7 12.0 GO:0040023 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.7 2.1 GO:0070640 vitamin D3 metabolic process(GO:0070640)
0.6 3.2 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.6 12.1 GO:0001843 neural tube closure(GO:0001843)
0.6 13.9 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.6 5.4 GO:0032264 IMP salvage(GO:0032264)
0.6 4.2 GO:0060088 auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.6 14.7 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.6 1.7 GO:0032964 collagen biosynthetic process(GO:0032964)
0.6 12.0 GO:0030537 larval locomotory behavior(GO:0008345) larval behavior(GO:0030537)
0.6 4.5 GO:0006198 cAMP catabolic process(GO:0006198)
0.6 3.4 GO:0051601 exocyst localization(GO:0051601)
0.6 12.7 GO:0015804 neutral amino acid transport(GO:0015804)
0.5 9.9 GO:0035924 cellular response to vascular endothelial growth factor stimulus(GO:0035924)
0.5 3.8 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.5 4.2 GO:0006171 cAMP biosynthetic process(GO:0006171)
0.5 11.0 GO:0048268 clathrin coat assembly(GO:0048268)
0.5 7.1 GO:0045580 regulation of T cell differentiation(GO:0045580)
0.5 13.5 GO:0003009 skeletal muscle contraction(GO:0003009)
0.5 3.4 GO:0021553 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.5 4.8 GO:1900449 regulation of glutamate receptor signaling pathway(GO:1900449)
0.5 5.7 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.5 10.3 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.5 1.8 GO:0035124 embryonic caudal fin morphogenesis(GO:0035124)
0.5 4.5 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059) dopamine transport(GO:0015872)
0.4 3.1 GO:0099639 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.4 1.3 GO:1900271 regulation of presynaptic cytosolic calcium ion concentration(GO:0099509) regulation of long-term synaptic potentiation(GO:1900271)
0.4 8.4 GO:0097581 lamellipodium assembly(GO:0030032) lamellipodium organization(GO:0097581)
0.4 4.9 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.4 10.3 GO:0051588 regulation of neurotransmitter secretion(GO:0046928) regulation of neurotransmitter transport(GO:0051588)
0.4 3.2 GO:0006013 mannose metabolic process(GO:0006013)
0.4 7.9 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.4 6.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.4 2.7 GO:1903038 negative regulation of T cell activation(GO:0050868) negative regulation of leukocyte cell-cell adhesion(GO:1903038)
0.4 10.6 GO:0048484 enteric nervous system development(GO:0048484)
0.4 3.5 GO:0070654 sensory epithelium regeneration(GO:0070654) epithelium regeneration(GO:1990399)
0.4 5.4 GO:0032526 response to retinoic acid(GO:0032526)
0.4 3.4 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661)
0.4 3.4 GO:0042102 positive regulation of mononuclear cell proliferation(GO:0032946) positive regulation of T cell proliferation(GO:0042102) positive regulation of lymphocyte proliferation(GO:0050671) positive regulation of leukocyte proliferation(GO:0070665)
0.4 14.8 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.4 3.2 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.4 1.4 GO:0002762 negative regulation of myeloid leukocyte differentiation(GO:0002762)
0.3 4.2 GO:0019471 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.3 1.4 GO:0035908 ventral aorta development(GO:0035908) pharyngeal arch artery morphogenesis(GO:0061626)
0.3 13.3 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.3 4.0 GO:0031274 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.3 6.5 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277) intestinal epithelial structure maintenance(GO:0060729)
0.3 7.8 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.3 7.3 GO:0031103 axon regeneration(GO:0031103)
0.3 0.9 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.3 1.4 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.3 10.8 GO:0032456 endocytic recycling(GO:0032456)
0.3 12.0 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.3 2.3 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.3 14.0 GO:0045010 actin nucleation(GO:0045010)
0.2 2.5 GO:0097320 membrane tubulation(GO:0097320)
0.2 0.7 GO:0003222 ventricular trabecula myocardium morphogenesis(GO:0003222)
0.2 2.9 GO:0072576 gland morphogenesis(GO:0022612) liver morphogenesis(GO:0072576)
0.2 8.6 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.2 3.5 GO:0022010 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.2 3.5 GO:0032482 Rab protein signal transduction(GO:0032482)
0.2 9.9 GO:0060037 pharyngeal system development(GO:0060037)
0.2 4.9 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.2 5.6 GO:1902476 chloride transmembrane transport(GO:1902476)
0.2 6.3 GO:0006376 mRNA splice site selection(GO:0006376)
0.2 4.9 GO:0003323 type B pancreatic cell development(GO:0003323)
0.2 5.6 GO:0021514 ventral spinal cord interneuron differentiation(GO:0021514)
0.2 8.5 GO:0031018 endocrine pancreas development(GO:0031018)
0.2 17.2 GO:0030833 regulation of actin filament polymerization(GO:0030833)
0.2 2.6 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.2 11.4 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.2 6.1 GO:0006306 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.2 3.8 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.2 0.8 GO:0019532 oxalate transport(GO:0019532)
0.2 3.5 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.2 7.4 GO:0007160 cell-matrix adhesion(GO:0007160)
0.2 14.7 GO:0090630 activation of GTPase activity(GO:0090630)
0.2 0.5 GO:1990697 protein depalmitoleylation(GO:1990697)
0.2 7.0 GO:0008016 regulation of heart contraction(GO:0008016)
0.2 3.4 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.2 2.1 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.2 2.2 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.2 4.6 GO:0006909 phagocytosis(GO:0006909)
0.2 1.5 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 4.9 GO:0007416 synapse assembly(GO:0007416)
0.1 5.5 GO:0045214 sarcomere organization(GO:0045214)
0.1 3.4 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 8.2 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 2.3 GO:0043507 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.1 9.1 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015)
0.1 4.5 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.1 5.1 GO:0008284 positive regulation of cell proliferation(GO:0008284)
0.1 4.0 GO:0051781 positive regulation of cell division(GO:0051781)
0.1 9.4 GO:0016485 protein processing(GO:0016485)
0.1 1.7 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.1 3.4 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.1 5.3 GO:0033339 pectoral fin development(GO:0033339)
0.1 6.7 GO:0001756 somitogenesis(GO:0001756)
0.1 4.2 GO:0050808 synapse organization(GO:0050808)
0.1 3.5 GO:0006836 neurotransmitter transport(GO:0006836)
0.1 8.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 4.5 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.1 11.2 GO:0007018 microtubule-based movement(GO:0007018)
0.1 0.4 GO:0000305 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.1 1.2 GO:0045104 intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104)
0.1 14.0 GO:0001525 angiogenesis(GO:0001525)
0.1 0.8 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 1.5 GO:0046530 photoreceptor cell differentiation(GO:0046530)
0.0 1.4 GO:0071599 otic vesicle development(GO:0071599)
0.0 0.4 GO:0061035 regulation of cartilage development(GO:0061035)
0.0 0.8 GO:1901663 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.6 GO:0001706 endoderm formation(GO:0001706)
0.0 2.2 GO:0010506 regulation of autophagy(GO:0010506)
0.0 3.1 GO:0007368 determination of left/right symmetry(GO:0007368)
0.0 0.9 GO:0000077 DNA damage checkpoint(GO:0000077)
0.0 2.1 GO:0098609 cell-cell adhesion(GO:0098609)
0.0 3.0 GO:0032259 methylation(GO:0032259)
0.0 0.2 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 12.3 GO:0030314 junctional membrane complex(GO:0030314)
2.4 16.6 GO:0044295 axonal growth cone(GO:0044295)
2.2 11.0 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
2.0 19.9 GO:0016602 CCAAT-binding factor complex(GO:0016602)
2.0 7.9 GO:0016586 RSC complex(GO:0016586)
1.5 21.3 GO:0030315 T-tubule(GO:0030315)
1.4 22.0 GO:0071564 npBAF complex(GO:0071564)
1.3 15.5 GO:0005640 nuclear outer membrane(GO:0005640)
1.1 5.6 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
1.1 4.3 GO:0042584 chromaffin granule membrane(GO:0042584)
0.9 9.6 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.8 11.1 GO:0044666 MLL3/4 complex(GO:0044666)
0.8 13.3 GO:0031672 A band(GO:0031672)
0.8 11.6 GO:0043195 terminal bouton(GO:0043195)
0.8 9.2 GO:0043209 myelin sheath(GO:0043209)
0.7 8.8 GO:0005869 dynactin complex(GO:0005869)
0.7 7.2 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.6 4.9 GO:0005921 gap junction(GO:0005921)
0.6 13.5 GO:0005861 troponin complex(GO:0005861)
0.6 4.6 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.6 6.3 GO:0030056 hemidesmosome(GO:0030056)
0.6 4.5 GO:0016328 lateral plasma membrane(GO:0016328)
0.5 10.8 GO:0034707 chloride channel complex(GO:0034707)
0.5 5.4 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.5 21.9 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.5 9.7 GO:0048786 presynaptic active zone(GO:0048786)
0.5 22.3 GO:0042383 sarcolemma(GO:0042383)
0.4 4.9 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.4 2.5 GO:0005913 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.4 7.6 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.4 12.4 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.3 10.8 GO:0055038 recycling endosome membrane(GO:0055038)
0.3 16.7 GO:0005604 basement membrane(GO:0005604)
0.3 3.8 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.3 17.0 GO:0042641 actomyosin(GO:0042641)
0.3 8.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.3 9.6 GO:0030426 growth cone(GO:0030426)
0.3 3.0 GO:0099634 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.3 12.2 GO:0005581 collagen trimer(GO:0005581)
0.3 17.3 GO:0016324 apical plasma membrane(GO:0016324)
0.3 3.4 GO:0000145 exocyst(GO:0000145)
0.3 31.1 GO:0030424 axon(GO:0030424)
0.3 6.6 GO:0016342 catenin complex(GO:0016342)
0.2 7.7 GO:0031225 anchored component of membrane(GO:0031225)
0.2 2.8 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.2 4.2 GO:0032587 ruffle membrane(GO:0032587)
0.1 8.4 GO:0031012 extracellular matrix(GO:0031012)
0.1 3.3 GO:0043025 neuronal cell body(GO:0043025)
0.1 6.3 GO:0030496 midbody(GO:0030496)
0.1 77.0 GO:0005615 extracellular space(GO:0005615)
0.1 1.5 GO:0032783 ELL-EAF complex(GO:0032783)
0.1 7.1 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.1 8.8 GO:0005882 intermediate filament(GO:0005882)
0.1 64.4 GO:0005887 integral component of plasma membrane(GO:0005887)
0.1 6.0 GO:0030027 lamellipodium(GO:0030027)
0.1 27.8 GO:0030054 cell junction(GO:0030054)
0.1 3.5 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 25.6 GO:0005667 transcription factor complex(GO:0005667)
0.1 4.5 GO:0070382 exocytic vesicle(GO:0070382)
0.1 22.0 GO:0005576 extracellular region(GO:0005576)
0.1 2.6 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1 3.8 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 0.4 GO:0044453 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1 1.0 GO:0032156 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.1 2.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 2.7 GO:0031901 early endosome membrane(GO:0031901)
0.0 3.4 GO:0000793 condensed chromosome(GO:0000793)
0.0 8.0 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 8.8 GO:0005874 microtubule(GO:0005874)
0.0 8.1 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 6.7 GO:0005794 Golgi apparatus(GO:0005794)
0.0 0.2 GO:0005902 microvillus(GO:0005902)
0.0 2.4 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 2.7 GO:0016607 nuclear speck(GO:0016607)
0.0 70.8 GO:0016021 integral component of membrane(GO:0016021)
0.0 1.8 GO:0031410 cytoplasmic vesicle(GO:0031410)
0.0 0.8 GO:0035097 histone methyltransferase complex(GO:0035097)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 14.7 GO:0004736 pyruvate carboxylase activity(GO:0004736)
3.1 15.4 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
3.0 9.1 GO:0036374 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
2.8 11.4 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
2.4 21.9 GO:0016531 copper chaperone activity(GO:0016531)
2.0 18.0 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
1.8 10.8 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
1.7 6.9 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
1.6 4.9 GO:0005243 gap junction channel activity(GO:0005243)
1.5 6.1 GO:0004046 aminoacylase activity(GO:0004046)
1.4 5.7 GO:0030368 interleukin-17 receptor activity(GO:0030368)
1.4 5.6 GO:0030274 LIM domain binding(GO:0030274)
1.4 11.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
1.4 9.6 GO:0004157 dihydropyrimidinase activity(GO:0004157)
1.2 18.3 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
1.2 3.5 GO:0039706 co-receptor binding(GO:0039706)
1.1 10.2 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
1.1 5.6 GO:0004890 GABA-A receptor activity(GO:0004890)
1.1 5.4 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
1.1 5.4 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
1.1 5.4 GO:2001070 starch binding(GO:2001070)
1.1 3.2 GO:0004383 guanylate cyclase activity(GO:0004383)
1.0 4.2 GO:0004016 adenylate cyclase activity(GO:0004016)
1.0 3.1 GO:0035259 glucocorticoid receptor binding(GO:0035259)
1.0 3.9 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
1.0 6.7 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.9 13.2 GO:0038191 neuropilin binding(GO:0038191)
0.9 7.5 GO:0034452 dynactin binding(GO:0034452)
0.9 16.4 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.9 13.3 GO:0051879 Hsp90 protein binding(GO:0051879)
0.9 7.9 GO:0048495 Roundabout binding(GO:0048495)
0.9 8.7 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.9 3.5 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.8 4.7 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.8 11.0 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.8 3.8 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.7 13.9 GO:0046875 ephrin receptor binding(GO:0046875)
0.7 15.2 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.7 15.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.7 10.6 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.7 2.7 GO:0070412 R-SMAD binding(GO:0070412)
0.7 8.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.6 7.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.6 7.2 GO:0003785 actin monomer binding(GO:0003785)
0.6 8.3 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.6 2.3 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.6 9.2 GO:0002039 p53 binding(GO:0002039)
0.6 6.3 GO:0030506 ankyrin binding(GO:0030506)
0.6 5.7 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.6 8.0 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.6 8.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.6 2.8 GO:0015157 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.5 3.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.5 1.9 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.4 4.0 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.4 6.9 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.4 5.9 GO:0005080 protein kinase C binding(GO:0005080)
0.4 12.7 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.4 3.4 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.4 9.2 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.4 4.9 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.4 4.5 GO:0030552 cAMP binding(GO:0030552)
0.4 48.0 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.4 3.8 GO:0005504 fatty acid binding(GO:0005504)
0.4 8.8 GO:0001786 phosphatidylserine binding(GO:0001786)
0.3 4.5 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.3 4.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.3 4.2 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.3 6.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.3 14.2 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.3 2.3 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.3 3.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.3 6.7 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.3 6.7 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.3 3.4 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.3 21.5 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.3 7.9 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.3 23.4 GO:0015293 symporter activity(GO:0015293)
0.3 14.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.3 1.4 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.3 8.4 GO:0005178 integrin binding(GO:0005178)
0.3 54.9 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.3 8.8 GO:0008201 heparin binding(GO:0008201)
0.2 2.7 GO:0031267 small GTPase binding(GO:0031267)
0.2 5.3 GO:0004180 carboxypeptidase activity(GO:0004180)
0.2 4.7 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.2 12.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 4.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.2 9.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.2 17.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.2 2.8 GO:0070411 I-SMAD binding(GO:0070411)
0.2 2.1 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.2 8.7 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.2 2.0 GO:0050321 tau-protein kinase activity(GO:0050321)
0.2 0.5 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.2 3.2 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.2 7.6 GO:0008013 beta-catenin binding(GO:0008013)
0.2 3.8 GO:0016208 AMP binding(GO:0016208)
0.2 4.1 GO:0005044 scavenger receptor activity(GO:0005044)
0.2 0.8 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.2 5.0 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.1 8.6 GO:0051287 NAD binding(GO:0051287)
0.1 4.0 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.1 1.7 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 4.6 GO:0017124 SH3 domain binding(GO:0017124)
0.1 65.4 GO:0005509 calcium ion binding(GO:0005509)
0.1 3.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.8 GO:0048039 ubiquinone binding(GO:0048039)
0.1 5.2 GO:0003777 microtubule motor activity(GO:0003777)
0.1 0.9 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 9.2 GO:0051082 unfolded protein binding(GO:0051082)
0.1 0.4 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 11.1 GO:0019901 protein kinase binding(GO:0019901)
0.1 4.7 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 1.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 90.7 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.1 2.6 GO:0030145 manganese ion binding(GO:0030145)
0.1 5.2 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.1 3.4 GO:0000149 SNARE binding(GO:0000149)
0.1 1.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 24.9 GO:1990837 sequence-specific double-stranded DNA binding(GO:1990837)
0.1 9.7 GO:0008017 microtubule binding(GO:0008017)
0.1 21.9 GO:0003779 actin binding(GO:0003779)
0.1 11.8 GO:0005543 phospholipid binding(GO:0005543)
0.0 3.3 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 1.7 GO:0004497 monooxygenase activity(GO:0004497)
0.0 1.5 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.2 GO:0008301 DNA binding, bending(GO:0008301)
0.0 1.0 GO:0060090 binding, bridging(GO:0060090)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 9.9 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
1.8 5.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.8 9.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.5 6.9 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.5 8.9 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.4 19.9 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.4 8.5 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.3 4.5 PID S1P S1P2 PATHWAY S1P2 pathway
0.3 4.6 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.3 9.5 PID ATM PATHWAY ATM pathway
0.3 25.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.2 3.9 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.2 7.1 PID HNF3A PATHWAY FOXA1 transcription factor network
0.2 4.4 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.2 4.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.2 2.5 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.2 16.5 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.2 9.2 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 4.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 2.7 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 3.0 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 3.6 PID E2F PATHWAY E2F transcription factor network
0.0 0.1 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 1.0 PID FGF PATHWAY FGF signaling pathway
0.0 0.3 PID AP1 PATHWAY AP-1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 9.9 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
1.4 6.9 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
1.4 9.6 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
1.3 13.9 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
1.1 9.2 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
1.1 11.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
1.1 13.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
1.0 6.9 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.9 2.7 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.8 9.6 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.6 5.5 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.6 7.9 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.5 11.3 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.5 3.9 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.4 3.2 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.4 2.9 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.3 4.9 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.3 4.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.3 8.4 REACTOME MYOGENESIS Genes involved in Myogenesis
0.3 4.2 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.3 5.0 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.2 2.6 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.2 4.6 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1 4.0 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 22.0 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.1 1.9 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 2.6 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.1 4.9 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 1.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 2.7 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 3.8 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 2.9 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 3.8 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.9 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway