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Results for alx1

Z-value: 0.95

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Transcription factors associated with alx1

Gene Symbol Gene ID Gene Info
alx1
ENSDARG00000062824 ALX homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
alx1dr10_dc_chr18_+_16257606_16257627-0.802.1e-04Click!

Activity profile of alx1 motif

Sorted Z-values of alx1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of alx1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr19_+_15536640 5.19 ENSDART00000098970
lin28a
lin-28 homolog A (C. elegans)
chr8_+_45326435 4.53 ENSDART00000134161
pabpc1l
poly(A) binding protein, cytoplasmic 1-like
chr10_-_25246786 3.34 ENSDART00000036906
kpna7
karyopherin alpha 7 (importin alpha 8)
chr5_+_37303599 3.34 ENSDART00000097754
ENSDART00000162470
tmprss4b
transmembrane protease, serine 4b
chr5_+_57254393 3.30 ENSDART00000050949
btg4
B-cell translocation gene 4
chr21_+_25740782 3.30 ENSDART00000021620
cldnd
claudin d
chr10_-_21404605 3.22 ENSDART00000125167
avd
avidin
chr12_-_14104939 3.02 ENSDART00000152742
buc2l
bucky ball 2-like
chr7_-_51497945 3.00 ENSDART00000054591
bmp15
bone morphogenetic protein 15
chr11_-_1524107 2.90 ENSDART00000110097
si:ch73-303b9.1
si:ch73-303b9.1
chr19_-_20819477 2.80 ENSDART00000151356
dazl
deleted in azoospermia-like
chr16_+_39209567 2.70 ENSDART00000121756
sybu
syntabulin (syntaxin-interacting)
chr14_+_34150130 2.65 ENSDART00000132193
ENSDART00000141058
wnt8a
BX927327.1
wingless-type MMTV integration site family, member 8a
ENSDARG00000105311
chr24_-_14446593 2.61

chr24_+_12689711 2.59 ENSDART00000114762
nanog
nanog homeobox
chr3_+_32285237 2.57 ENSDART00000157324
prrg2
proline rich Gla (G-carboxyglutamic acid) 2
chr10_-_34971985 2.54 ENSDART00000141201
ccna1
cyclin A1
chr16_-_29452509 2.50 ENSDART00000148787
s100a1
S100 calcium binding protein A1
chr22_-_17627900 2.49 ENSDART00000138483
si:ch73-243b8.4
si:ch73-243b8.4
chr18_-_43890836 2.31 ENSDART00000087382
ddx6
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr19_-_20819101 2.29 ENSDART00000137590
dazl
deleted in azoospermia-like
chr17_+_16038358 2.28 ENSDART00000155336
si:ch73-204p21.2
si:ch73-204p21.2
chr10_+_6925373 2.12 ENSDART00000128866
ddx4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr11_-_34909095 2.12 ENSDART00000017393
traip
TRAF-interacting protein
chr24_+_8702288 2.05 ENSDART00000114810
sycp2l
synaptonemal complex protein 2-like
chr16_-_46613217 1.89 ENSDART00000127212
si:dkey-152b24.6
si:dkey-152b24.6
chr24_+_19270877 1.87

chr1_-_54570813 1.83 ENSDART00000098615
nanos3
nanos homolog 3
chr25_+_7261050 1.83 ENSDART00000163017
prc1a
protein regulator of cytokinesis 1a
chr11_-_6442588 1.78 ENSDART00000137879
zgc:162969
zgc:162969
chr20_-_23527234 1.73 ENSDART00000004625
zar1
zygote arrest 1
chr17_+_16038103 1.73 ENSDART00000155005
si:ch73-204p21.2
si:ch73-204p21.2
KN149710v1_+_38638 1.72

chr19_-_5186692 1.72 ENSDART00000037007
tpi1a
triosephosphate isomerase 1a
chr11_+_34909167 1.69 ENSDART00000110839
mon1a
MON1 secretory trafficking family member A
chr16_-_39209426 1.69

chr14_-_8634381 1.69 ENSDART00000129030
zgc:153681
zgc:153681
chr5_+_58936399 1.68

chr11_+_34909244 1.68 ENSDART00000110839
mon1a
MON1 secretory trafficking family member A
chr16_+_42567707 1.60 ENSDART00000166640
si:ch211-215k15.5
si:ch211-215k15.5
chr11_+_23799984 1.58

chr1_-_18118467 1.57 ENSDART00000142026
si:dkey-167i21.2
si:dkey-167i21.2
chr22_-_17627831 1.45 ENSDART00000138483
si:ch73-243b8.4
si:ch73-243b8.4
chr16_-_29451902 1.45

chr18_+_20571460 1.44 ENSDART00000151990
wee2
WEE1 homolog 2 (S. pombe)
chr10_-_25448712 1.44 ENSDART00000140023
grik1a
glutamate receptor, ionotropic, kainate 1a
chr10_+_19625897 1.43

chr24_+_12689887 1.43 ENSDART00000114762
nanog
nanog homeobox
chr8_+_41003546 1.42 ENSDART00000129344
gpat2
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr5_-_8712114 1.42 ENSDART00000134896
ENSDART00000147000
lrp13
low-density lipoprotein receptor related-protein 13
chr15_-_23484927 1.42 ENSDART00000148840
kmt2a
lysine (K)-specific methyltransferase 2A
chr12_-_13511174 1.41 ENSDART00000133895
ghdc
GH3 domain containing
chr10_-_34971926 1.40 ENSDART00000141201
ccna1
cyclin A1
chr11_-_40154790 1.39 ENSDART00000086296
trim62
tripartite motif containing 62
chr7_-_24604255 1.38 ENSDART00000173920
adad2
adenosine deaminase domain containing 2
chr7_+_28341426 1.36 ENSDART00000019991
slc7a6os
solute carrier family 7, member 6 opposite strand
chr24_-_30929990 1.35

chr1_+_50547385 1.32 ENSDART00000132141
btbd3a
BTB (POZ) domain containing 3a
chr22_+_4035577 1.32 ENSDART00000170620
ctxn1
cortexin 1
chr6_+_29702868 1.30 ENSDART00000114172
pde6d
phosphodiesterase 6D, cGMP-specific, rod, delta
chr2_-_26941084 1.30 ENSDART00000134685
ENSDART00000056787
zgc:113691
zgc:113691
chr1_-_7160294 1.29 ENSDART00000174972
BX908756.2
ENSDARG00000108483
chr2_+_6341404 1.27 ENSDART00000076700
zp3b
zona pellucida glycoprotein 3b
chr8_+_49128711 1.27 ENSDART00000079631
rad21l1
RAD21 cohesin complex component like 1
chr21_-_32027717 1.26 ENSDART00000131651
ENSDARG00000073961
ENSDARG00000073961
chr20_+_16740320 1.25 ENSDART00000152359
tmem30ab
transmembrane protein 30Ab
chr16_+_33209956 1.24 ENSDART00000101943
rragca
Ras-related GTP binding Ca
chr7_+_24855467 1.23 ENSDART00000077217
zgc:101765
zgc:101765
chr8_+_25126238 1.23 ENSDART00000136505
gnai3
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr15_+_35089305 1.23 ENSDART00000156515
zgc:55621
zgc:55621
chr13_+_24549364 1.22 ENSDART00000139854
zgc:66426
zgc:66426
chr20_+_32620786 1.22 ENSDART00000147319
scml4
sex comb on midleg-like 4 (Drosophila)
chr20_+_19304349 1.20

chr5_-_8712068 1.19 ENSDART00000134896
ENSDART00000147000
lrp13
low-density lipoprotein receptor related-protein 13
chr9_+_29737843 1.19 ENSDART00000176057
rnf17
ring finger protein 17
chr7_+_22042296 1.18 ENSDART00000123457
TMEM102
transmembrane protein 102
chr16_+_19831573 1.18 ENSDART00000135359
macc1
metastasis associated in colon cancer 1
chr8_+_28362546 1.18 ENSDART00000062682
adipor1b
adiponectin receptor 1b
chr3_+_28729443 1.18 ENSDART00000077235
alg1
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
chr24_-_10935904 1.17 ENSDART00000003195
chmp4c
charged multivesicular body protein 4C
chr6_+_40925259 1.17 ENSDART00000002728
ENSDART00000145153
eif4enif1
eukaryotic translation initiation factor 4E nuclear import factor 1
chr14_+_25950244 1.14 ENSDART00000113804
ENSDART00000159054
CCDC69
coiled-coil domain containing 69
chr18_-_50439653 1.13 ENSDART00000151038
CU862078.1
ENSDARG00000096262
chr2_+_23383492 1.13 ENSDART00000170669
csnk1g2a
casein kinase 1, gamma 2a
chr1_+_35253862 1.11 ENSDART00000139636
zgc:152968
zgc:152968
chr19_+_38262119 1.11 ENSDART00000042276
nxph1
neurexophilin 1
chr25_+_29219342 1.10 ENSDART00000108692
ENSDART00000077445
pim3
Pim-3 proto-oncogene, serine/threonine kinase
chr13_+_22973764 1.09 ENSDART00000110266
pik3ap1
phosphoinositide-3-kinase adaptor protein 1
chr18_+_20571400 1.09 ENSDART00000151990
wee2
WEE1 homolog 2 (S. pombe)
chr10_+_17277353 1.09 ENSDART00000038780
sppl3
signal peptide peptidase 3
chr21_+_31216418 1.08 ENSDART00000178521
asl
argininosuccinate lyase
chr17_+_26704439 1.07 ENSDART00000114927
nrde2
NRDE-2, necessary for RNA interference, domain containing
chr16_+_29574449 1.07 ENSDART00000148450
ctss2.1
cathepsin S, ortholog2, tandem duplicate 1
chr22_-_551324 1.07

chr5_+_6391432 1.05 ENSDART00000170564
ENSDART00000086666
stpg2
sperm-tail PG-rich repeat containing 2
chr14_-_33141111 1.04 ENSDART00000147059
lamp2
lysosomal-associated membrane protein 2
chr13_-_32595667 1.03 ENSDART00000012232
pdss2
prenyl (decaprenyl) diphosphate synthase, subunit 2
chr15_-_16241412 1.02 ENSDART00000156352
si:ch211-259g3.4
si:ch211-259g3.4
KN150065v1_-_622 1.02

chr14_-_26199859 1.01 ENSDART00000054175
ENSDART00000145625
smad5
SMAD family member 5
chr12_-_30244575 1.01 ENSDART00000152981
tdrd1
tudor domain containing 1
chr14_+_31265616 1.01

chr13_-_32768928 1.01 ENSDART00000163757
rock2a
rho-associated, coiled-coil containing protein kinase 2a
chr21_-_36710989 1.00 ENSDART00000086060
mrpl22
mitochondrial ribosomal protein L22
chr13_-_32595706 1.00 ENSDART00000012232
pdss2
prenyl (decaprenyl) diphosphate synthase, subunit 2
chr2_+_30013468 1.00 ENSDART00000139566
rbm33b
RNA binding motif protein 33b
chr13_-_25590425 1.00 ENSDART00000142404
si:dkey-192p21.6
si:dkey-192p21.6
chr20_+_54404987 0.99 ENSDART00000099338
actr10
ARP10 actin related protein 10 homolog
chr14_-_21816253 0.99 ENSDART00000113752
si:dkey-6i22.5
si:dkey-6i22.5
chr22_+_1153361 0.99 ENSDART00000159761
irf6
interferon regulatory factor 6
chr2_-_27892824 0.98

chr22_+_17803309 0.98 ENSDART00000136016
hapln4
hyaluronan and proteoglycan link protein 4
chr11_+_38858311 0.98 ENSDART00000155746
cdc42
cell division cycle 42
chr20_+_32620937 0.98 ENSDART00000147319
scml4
sex comb on midleg-like 4 (Drosophila)
chr23_-_35691369 0.98 ENSDART00000142369
mfsd5
major facilitator superfamily domain containing 5
chr21_+_34053739 0.97 ENSDART00000147519
mtmr1b
myotubularin related protein 1b
chr2_-_26941232 0.97 ENSDART00000134685
ENSDART00000056787
zgc:113691
zgc:113691
chr8_+_11387135 0.96

chr5_-_61134500 0.95 ENSDART00000079855
im:7138535
im:7138535
chr6_-_41031013 0.94 ENSDART00000134293
trub2
TruB pseudouridine (psi) synthase family member 2
chr8_+_19945820 0.94 ENSDART00000134124
znf692
zinc finger protein 692
chr12_-_30244042 0.94 ENSDART00000152878
tdrd1
tudor domain containing 1
chr23_+_28464194 0.94 ENSDART00000133736
CT025585.1
ENSDARG00000093306
chr8_-_22720007 0.93

chr20_-_37910887 0.92 ENSDART00000147529
batf3
basic leucine zipper transcription factor, ATF-like 3
chr8_-_1833095 0.90 ENSDART00000114476
ENSDART00000091235
ENSDART00000140077
pi4kab
phosphatidylinositol 4-kinase, catalytic, alpha b
chr18_+_19467527 0.90 ENSDART00000079695
zwilch
zwilch kinetochore protein
chr15_+_36075206 0.90 ENSDART00000019976
rhbdd1
rhomboid domain containing 1
chr21_-_25765319 0.90 ENSDART00000101219
mettl27
methyltransferase like 27
chr16_-_32865452 0.89

chr16_+_47283253 0.89 ENSDART00000062507
ica1
islet cell autoantigen 1
chr13_-_36015558 0.88 ENSDART00000133072
med6
mediator complex subunit 6
chr16_-_25452949 0.87 ENSDART00000167574
rbfa
ribosome binding factor A
chr7_+_12675166 0.87 ENSDART00000027329
fth1a
ferritin, heavy polypeptide 1a
chr21_-_14154489 0.87 ENSDART00000114715
man1b1a
mannosidase, alpha, class 1B, member 1a
chr23_+_32102030 0.85 ENSDART00000145501
tpx2
TPX2, microtubule-associated, homolog (Xenopus laevis)
chr1_+_8010026 0.85 ENSDART00000152142
zgc:77849
zgc:77849
chr3_-_40695299 0.84 ENSDART00000134026
wipi2
WD repeat domain, phosphoinositide interacting 2
chr23_-_43916621 0.83 ENSDART00000015777
abce1
ATP-binding cassette, sub-family E (OABP), member 1
chr17_+_25425914 0.82 ENSDART00000030691
clic4
chloride intracellular channel 4
chr24_+_16924542 0.82 ENSDART00000014787
pip4k2aa
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha a
chr19_-_20819057 0.82 ENSDART00000136826
dazl
deleted in azoospermia-like
chr9_+_35205519 0.81 ENSDART00000100700
gabpa
GA binding protein transcription factor, alpha subunit
chr8_-_44247277 0.81

chr8_+_50964745 0.81 ENSDART00000013870
ENSDARG00000007359
ENSDARG00000007359
chr1_+_50547341 0.81 ENSDART00000132141
btbd3a
BTB (POZ) domain containing 3a
chr25_-_28630138 0.80

chr16_+_35448634 0.80 ENSDART00000171608
rab42b
RAB42, member RAS oncogene family
chr20_+_27341244 0.80 ENSDART00000123950
ENSDARG00000077377
ENSDARG00000077377
chr24_-_2454189 0.80 ENSDART00000093331
rreb1a
ras responsive element binding protein 1a
chr1_+_18118735 0.79 ENSDART00000078610
slc25a51a
solute carrier family 25, member 51a
chr6_+_48188549 0.78

chr24_-_30930178 0.78

chr16_+_33209755 0.78 ENSDART00000101943
rragca
Ras-related GTP binding Ca
chr2_-_57826189 0.78 ENSDART00000131420
si:dkeyp-68b7.5
si:dkeyp-68b7.5
chr10_-_32550351 0.77 ENSDART00000129395
uvrag
UV radiation resistance associated gene
chr15_+_21327206 0.77 ENSDART00000101000
gkup
glucuronokinase with putative uridyl pyrophosphorylase
chr6_+_50382153 0.77 ENSDART00000055504
cyc1
cytochrome c-1
chr14_-_26093969 0.77 ENSDART00000037999
b4galt7
xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I)
chr10_+_43953171 0.77

chr3_-_40695407 0.77 ENSDART00000134026
wipi2
WD repeat domain, phosphoinositide interacting 2
chr18_+_5066229 0.76 ENSDART00000157671
CABZ01080599.1
ENSDARG00000100626
chr24_-_21788942 0.76 ENSDART00000113092
abhd10b
abhydrolase domain containing 10b
chr18_+_8362265 0.74 ENSDART00000092053
chkb
choline kinase beta
chr13_+_31271568 0.73 ENSDART00000019202
tdrd9
tudor domain containing 9
chr19_-_18664670 0.73 ENSDART00000108627
snx10a
sorting nexin 10a
chr16_+_39209538 0.73 ENSDART00000121756
sybu
syntabulin (syntaxin-interacting)
chr24_-_30929960 0.73

chr21_+_34053590 0.73 ENSDART00000147519
ENSDART00000158115
ENSDART00000029599
ENSDART00000145123
mtmr1b
myotubularin related protein 1b
chr20_+_32620873 0.73 ENSDART00000147319
scml4
sex comb on midleg-like 4 (Drosophila)
chr5_+_37303707 0.72 ENSDART00000097754
ENSDART00000162470
tmprss4b
transmembrane protease, serine 4b
chr3_+_37507517 0.72 ENSDART00000075039
gosr2
golgi SNAP receptor complex member 2
chr18_+_20571785 0.72 ENSDART00000040074
wee2
WEE1 homolog 2 (S. pombe)
chr2_-_38380883 0.72 ENSDART00000088026
prmt5
protein arginine methyltransferase 5
chr20_-_16271738 0.72 ENSDART00000012476
coa7
cytochrome c oxidase assembly factor 7
chr6_-_12665211 0.72 ENSDART00000150887
ical1
islet cell autoantigen 1-like
chr18_+_27769446 0.72

chr2_-_26940965 0.71 ENSDART00000134685
ENSDART00000056787
zgc:113691
zgc:113691
chr16_+_47283374 0.71 ENSDART00000062507
ica1
islet cell autoantigen 1
chr16_-_12582192 0.71

chr5_+_25133592 0.71 ENSDART00000098467
abhd17b
abhydrolase domain containing 17B
chr2_-_22980899 0.71 ENSDART00000056963
stk25b
serine/threonine kinase 25b
chr8_+_45326523 0.70 ENSDART00000145011
pabpc1l
poly(A) binding protein, cytoplasmic 1-like
chr4_-_66538843 0.70 ENSDART00000165173
BX548011.1
ENSDARG00000103357
chr21_-_13026036 0.70 ENSDART00000135623
fam219aa
family with sequence similarity 219, member Aa
chr19_+_40482359 0.69 ENSDART00000151365
ENSDART00000140926
zmym4
zinc finger, MYM-type 4
chr19_+_42657913 0.69 ENSDART00000131574
ENSDART00000135436
jtb
jumping translocation breakpoint
chr17_+_16082165 0.69 ENSDART00000132203
znf395a
zinc finger protein 395a
chr14_+_23420053 0.69 ENSDART00000006373
ndfip1
Nedd4 family interacting protein 1
chr23_+_28464298 0.69 ENSDART00000133736
CT025585.1
ENSDARG00000093306
chr15_-_43402935 0.68 ENSDART00000041677
serpine2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr16_+_42567668 0.68 ENSDART00000166640
si:ch211-215k15.5
si:ch211-215k15.5
chr23_+_17583666 0.68 ENSDART00000054738
gid8b
GID complex subunit 8 homolog b (S. cerevisiae)
chr24_-_14447519 0.68

chr5_-_19987344 0.68 ENSDART00000144232
ficd
FIC domain containing
chr23_+_28464143 0.68 ENSDART00000133736
CT025585.1
ENSDARG00000093306
chr18_+_36160190 0.68 ENSDART00000146068
BX927288.1
ENSDARG00000092309
chr3_-_39554099 0.67 ENSDART00000145303
b9d1
B9 protein domain 1
chr13_-_35346618 0.66 ENSDART00000057052
slx4ip
SLX4 interacting protein
chr21_-_36768113 0.66 ENSDART00000018350
cnot8
CCR4-NOT transcription complex, subunit 8

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 5.9 GO:0060965 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
1.2 4.6 GO:0043622 cortical microtubule organization(GO:0043622)
0.8 3.4 GO:0021512 spinal cord anterior/posterior patterning(GO:0021512) cell proliferation involved in pronephros development(GO:0039015) cell proliferation involved in kidney development(GO:0072111)
0.8 3.0 GO:0042698 ovarian follicle development(GO:0001541) ovulation cycle process(GO:0022602) ovulation cycle(GO:0042698)
0.7 2.0 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.6 3.2 GO:0060631 regulation of meiosis I(GO:0060631)
0.6 1.7 GO:0019242 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.5 1.5 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.4 4.4 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.4 2.1 GO:0048608 gonad development(GO:0008406) reproductive structure development(GO:0048608) reproductive system development(GO:0061458)
0.3 3.1 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.3 1.0 GO:0060775 protein catabolic process in the vacuole(GO:0007039) mediolateral intercalation(GO:0060031) planar cell polarity pathway involved in gastrula mediolateral intercalation(GO:0060775)
0.3 1.7 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.3 3.3 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.2 0.9 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.2 0.8 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.2 0.6 GO:1903895 regulation of endoplasmic reticulum unfolded protein response(GO:1900101) negative regulation of endoplasmic reticulum unfolded protein response(GO:1900102) regulation of IRE1-mediated unfolded protein response(GO:1903894) negative regulation of IRE1-mediated unfolded protein response(GO:1903895)
0.2 1.0 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.2 0.6 GO:0006680 glucosylceramide catabolic process(GO:0006680)
0.2 0.7 GO:0070986 left/right axis specification(GO:0070986)
0.2 1.8 GO:0000022 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231) mitotic spindle midzone assembly(GO:0051256)
0.2 0.9 GO:0072395 signal transduction involved in cell cycle checkpoint(GO:0072395)
0.2 1.5 GO:0048532 anatomical structure arrangement(GO:0048532)
0.2 1.3 GO:0034063 stress granule assembly(GO:0034063)
0.2 6.1 GO:0006623 protein targeting to vacuole(GO:0006623)
0.2 1.3 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.2 0.9 GO:0006083 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.2 0.9 GO:1902425 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987) regulation of mitotic attachment of spindle microtubules to kinetochore(GO:1902423) positive regulation of attachment of mitotic spindle microtubules to kinetochore(GO:1902425) RNA localization to chromatin(GO:1990280)
0.1 0.3 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.1 1.6 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.1 2.2 GO:0035803 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1 0.6 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.1 1.8 GO:2000223 regulation of BMP signaling pathway involved in heart jogging(GO:2000223)
0.1 3.3 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.1 1.7 GO:0050796 regulation of insulin secretion(GO:0050796)
0.1 1.1 GO:0006591 ornithine metabolic process(GO:0006591)
0.1 1.4 GO:0048339 paraxial mesoderm development(GO:0048339)
0.1 0.5 GO:0030238 male sex determination(GO:0030238) androst-4-ene-3,17-dione biosynthetic process(GO:1903449)
0.1 0.3 GO:0034643 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497) establishment of mitochondrion localization(GO:0051654)
0.1 1.3 GO:0045332 phospholipid translocation(GO:0045332)
0.1 0.6 GO:0006102 isocitrate metabolic process(GO:0006102)
0.1 1.1 GO:0006465 signal peptide processing(GO:0006465)
0.1 0.6 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 2.0 GO:0006743 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 1.2 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.1 0.7 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1 0.9 GO:1904356 regulation of telomere maintenance via telomere lengthening(GO:1904356)
0.1 0.6 GO:0006382 adenosine to inosine editing(GO:0006382)
0.1 0.6 GO:0051932 synaptic transmission, GABAergic(GO:0051932) regulation of postsynaptic membrane potential(GO:0060078)
0.1 0.3 GO:0030242 pexophagy(GO:0030242)
0.1 4.3 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.1 0.1 GO:0055064 chloride ion homeostasis(GO:0055064)
0.1 0.7 GO:0006004 fucose metabolic process(GO:0006004)
0.1 0.2 GO:0072116 kidney rudiment formation(GO:0072003) pronephros formation(GO:0072116)
0.1 0.2 GO:0071800 podosome assembly(GO:0071800)
0.1 0.2 GO:0051645 Golgi localization(GO:0051645)
0.1 0.6 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.1 3.5 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.1 2.0 GO:0071230 cellular response to amino acid stimulus(GO:0071230)
0.1 0.3 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 0.4 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.1 0.3 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 0.5 GO:0046386 deoxyribonucleotide catabolic process(GO:0009264) deoxyribose phosphate catabolic process(GO:0046386)
0.1 0.6 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.1 2.1 GO:0048813 dendrite morphogenesis(GO:0048813)
0.1 1.8 GO:0048599 oocyte development(GO:0048599)
0.1 1.4 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.1 0.4 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.1 0.6 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.1 0.3 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.1 0.5 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 0.7 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.1 0.8 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 0.4 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.9 GO:0006415 translational termination(GO:0006415)
0.0 4.1 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 3.8 GO:0045930 negative regulation of mitotic cell cycle(GO:0045930)
0.0 0.1 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0 0.3 GO:2001287 caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.5 GO:0042772 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.0 1.1 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.2 GO:0007063 regulation of sister chromatid cohesion(GO:0007063) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.9 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.3 GO:0010212 response to ionizing radiation(GO:0010212)
0.0 0.2 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 1.2 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.0 1.5 GO:0051225 spindle assembly(GO:0051225)
0.0 0.4 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.2 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0 0.4 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086)
0.0 0.4 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 1.7 GO:0007346 regulation of mitotic cell cycle(GO:0007346)
0.0 0.1 GO:1900364 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.0 1.4 GO:0030166 proteoglycan biosynthetic process(GO:0030166)
0.0 0.1 GO:0034505 tooth mineralization(GO:0034505)
0.0 1.3 GO:0007601 visual perception(GO:0007601)
0.0 0.7 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 1.9 GO:0015698 inorganic anion transport(GO:0015698)
0.0 1.0 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 1.4 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015)
0.0 0.1 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.0 0.4 GO:0031397 negative regulation of protein ubiquitination(GO:0031397) negative regulation of protein modification by small protein conjugation or removal(GO:1903321)
0.0 0.3 GO:0090481 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.1 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 1.2 GO:0008016 regulation of heart contraction(GO:0008016)
0.0 0.1 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.0 0.4 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0 0.8 GO:0042255 ribosome assembly(GO:0042255)
0.0 0.4 GO:0051014 actin filament severing(GO:0051014)
0.0 0.3 GO:0008354 germ cell migration(GO:0008354)
0.0 0.5 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.3 GO:0008078 mesodermal cell migration(GO:0008078)
0.0 0.2 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.4 GO:0030217 T cell differentiation(GO:0030217)
0.0 0.5 GO:0018198 peptidyl-cysteine modification(GO:0018198)
0.0 0.2 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.5 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.2 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.3 GO:0042493 response to drug(GO:0042493)
0.0 0.8 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.3 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.0 0.2 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.0 0.3 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.1 GO:1902766 wound healing, spreading of cells(GO:0044319) epiboly involved in wound healing(GO:0090505) skeletal muscle satellite cell migration(GO:1902766)
0.0 0.5 GO:0003341 cilium movement(GO:0003341)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.8 3.4 GO:0097189 apoptotic body(GO:0097189)
0.4 1.3 GO:0034990 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.3 1.0 GO:0031310 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.3 2.4 GO:0071546 pi-body(GO:0071546)
0.3 1.0 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.3 4.7 GO:0043186 P granule(GO:0043186)
0.3 2.0 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.2 1.2 GO:1990498 mitotic spindle microtubule(GO:1990498)
0.2 1.1 GO:0098553 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.2 6.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.2 2.7 GO:1990023 mitotic spindle midzone(GO:1990023)
0.2 1.7 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.2 1.0 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.2 3.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 1.9 GO:0070847 core mediator complex(GO:0070847)
0.1 1.6 GO:0030667 secretory granule membrane(GO:0030667)
0.1 0.9 GO:0070187 telosome(GO:0070187)
0.1 0.6 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 0.6 GO:0000796 condensin complex(GO:0000796)
0.1 1.6 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 1.2 GO:0000815 ESCRT III complex(GO:0000815)
0.1 0.7 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 1.0 GO:0005869 dynactin complex(GO:0005869)
0.1 0.4 GO:0071012 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.1 0.3 GO:0070876 SOSS complex(GO:0070876)
0.1 0.4 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 0.7 GO:0045180 basal cortex(GO:0045180)
0.1 0.5 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 1.1 GO:0034707 chloride channel complex(GO:0034707)
0.1 0.3 GO:0005749 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.7 GO:0005682 U5 snRNP(GO:0005682)
0.0 1.4 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.8 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 1.4 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.4 GO:0032039 integrator complex(GO:0032039)
0.0 1.6 GO:0030496 midbody(GO:0030496)
0.0 2.7 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 1.1 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.2 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 1.3 GO:0005930 axoneme(GO:0005930)
0.0 0.7 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 0.2 GO:0035101 FACT complex(GO:0035101)
0.0 0.3 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.2 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.8 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.2 GO:0002102 podosome(GO:0002102)
0.0 0.4 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.8 GO:0072686 mitotic spindle(GO:0072686)
0.0 1.1 GO:0016592 mediator complex(GO:0016592)
0.0 1.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.2 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.5 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.1 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.8 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.5 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 1.4 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 0.3 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.1 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 2.7 GO:0005815 microtubule organizing center(GO:0005815)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.2 GO:0009374 biotin binding(GO:0009374)
0.6 1.7 GO:0004807 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.5 5.9 GO:0008494 translation activator activity(GO:0008494)
0.5 3.2 GO:0070698 type I activin receptor binding(GO:0070698)
0.5 2.0 GO:0034584 piRNA binding(GO:0034584)
0.5 1.5 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.5 5.2 GO:0008266 poly(U) RNA binding(GO:0008266)
0.3 1.3 GO:1903231 mRNA binding involved in posttranscriptional gene silencing(GO:1903231)
0.3 2.0 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.3 1.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.2 3.4 GO:0019894 kinesin binding(GO:0019894)
0.2 0.9 GO:0050218 propionate-CoA ligase activity(GO:0050218)
0.2 0.8 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.2 3.3 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.2 1.8 GO:0035804 structural constituent of egg coat(GO:0035804)
0.2 0.6 GO:0004348 glucosylceramidase activity(GO:0004348)
0.2 1.7 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.2 2.0 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.2 1.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.2 0.6 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.2 0.9 GO:0034046 TFIIH-class transcription factor binding(GO:0001097) poly(C) RNA binding(GO:0017130) poly(G) binding(GO:0034046)
0.2 0.9 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 1.2 GO:0050699 WW domain binding(GO:0050699)
0.1 0.7 GO:0046922 peptide-O-fucosyltransferase activity(GO:0046922)
0.1 4.1 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.5 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.1 0.6 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 1.6 GO:0070411 I-SMAD binding(GO:0070411)
0.1 1.0 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.1 0.9 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 0.9 GO:0016724 ferroxidase activity(GO:0004322) ferric iron binding(GO:0008199) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.1 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.1 0.6 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.5 GO:0016805 dipeptidase activity(GO:0016805)
0.1 2.1 GO:0004659 prenyltransferase activity(GO:0004659)
0.1 0.3 GO:1990757 anaphase-promoting complex binding(GO:0010997) ubiquitin ligase activator activity(GO:1990757)
0.1 1.4 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 1.4 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.1 0.5 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.1 3.2 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.1 0.9 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 1.6 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 4.5 GO:0003724 RNA helicase activity(GO:0003724)
0.1 0.3 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.1 0.4 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.1 4.3 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 1.9 GO:0003727 single-stranded RNA binding(GO:0003727)
0.1 1.4 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.1 0.3 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 2.0 GO:0005109 frizzled binding(GO:0005109)
0.1 0.4 GO:0035197 siRNA binding(GO:0035197)
0.1 0.4 GO:0032190 acrosin binding(GO:0032190)
0.0 0.2 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.0 0.7 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 1.2 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.3 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.6 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 1.2 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.9 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 6.9 GO:0042802 identical protein binding(GO:0042802)
0.0 0.5 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.3 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.6 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.3 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.1 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.3 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.3 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.3 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.5 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.8 GO:0019209 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.0 0.8 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.5 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 1.1 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.5 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 0.5 GO:0005254 chloride channel activity(GO:0005254)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.7 GO:0015103 inorganic anion transmembrane transporter activity(GO:0015103)
0.0 2.7 GO:0008017 microtubule binding(GO:0008017)
0.0 0.8 GO:0004527 exonuclease activity(GO:0004527)
0.0 2.4 GO:0042393 histone binding(GO:0042393)
0.0 1.3 GO:0019904 protein domain specific binding(GO:0019904)
0.0 1.2 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.5 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.3 1.6 PID ALK2 PATHWAY ALK2 signaling events
0.3 2.2 PID S1P S1P4 PATHWAY S1P4 pathway
0.2 3.9 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 0.9 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 6.5 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.8 PID AURORA A PATHWAY Aurora A signaling
0.0 0.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.9 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.6 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.8 PID AURORA B PATHWAY Aurora B signaling
0.0 0.9 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.4 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.5 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.2 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.2 3.9 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.2 0.9 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 1.0 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 1.6 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 2.0 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 1.5 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 1.5 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 1.5 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 1.4 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 0.5 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 1.2 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.9 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.7 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 1.2 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.3 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.6 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 1.1 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.9 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 1.6 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.0 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.6 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.4 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.3 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.7 REACTOME PRE NOTCH EXPRESSION AND PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.0 0.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.6 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)